Publikationen/Publications

1. Oubari S, Naser E, Papathanasiou M, Luedike P, Hagenacker T, Thimm A, Rischpler C, Kessler L, Kimmich C, Hegenbart U, Schönland S, Rassaf T, Reinhardt HC, Jöckel KH, Dürig J, Dührsen U, Carpinteiro A. Impact of time to diagnosis on Mayo stages, treatment outcome, and survival in patients with AL amyloidosis and cardiac involvement. Eur J Haematol. 2021 Oct;107(4):449-457. doi: 10.1111/ejh.13681. Epub 2021 Jul 9.PMID: 34185342

2. Peruzzo R, Mattarei A, Azzolini M, Becker-Flegler KA, Romio M, Rigoni G, Carrer A, Biasutto L, Parrasia S, Kadow S, Managò A, Urbani A, Rossa A, Semenzato G, Soriano ME, Trentin L, Ahmad S, Edwards M, Gulbins E, Paradisi C, Zoratti M, Leanza L, Szabò I. Insight into the mechanism of cytotoxicity of membrane-permeant psoralenic Kv1.3 channel inhibitors by chemical dissection of a novel member of the family. Redox Biol. 2020 Oct;37:101705. doi: 10.1016/j.redox.2020.101705. Epub 2020 Sep 6. Erratum in: Redox Biol. 2021 Sep;45:102036. PMID: 33007503; PMCID: PMC7527709.

3. Carpinteiro A, Gripp B, Hoffmann M, Pöhlmann S, Hoertel N, Edwards MJ, Kamler M, Kornhuber J, Becker KA, Gulbins E. Inhibition of acid sphingomyelinase by ambroxol prevents SARS-CoV-2 entry into epithelial cells. J Biol Chem. 2021 Apr 22:100701. doi: 10.1016/j.jbc.2021.100701. Epub ahead of print. PMID: 33895135.

4. Carpinteiro A, Gulbins E. Analysis of Lipids in Ceramide-Enriched Membrane Domains. Methods Mol Biol. 2021;2187:207-213. doi: 10.1007/978-1-0716-0814-2_11.PMID: 32770508

5. Becker KA, Carpinteiro A, Hoffmann M, Pöhlmann S, Kornhuber J, Gulbins E. Ex vivo assay to evaluate the efficacy of drugs targeting sphingolipids in preventing SARS-CoV-2 infection of nasal epithelial cells. STAR Protoc. 2021 Mar 19;2(1):100356. doi: 0.1016/j.xpro.2021.100356. Epub 2021 Feb 3. PMID: 33558862; PMCID: PMC7857112

6. Carpinteiro A, Edwards MJ, Hoffmann M, Kochs G, Gripp B, Weigang S, Adams C, Carpinteiro E, Gulbins A, Keitsch S, Sehl C, Soddemann M, Wilker B, Kamler M, Bertsch T, Lang KS, Patel S, Wilson GC, Walter S, Hengel H, Pöhlmann S, Lang PA, Kornhuber J, Becker KA, Ahmad SA, Fassbender K, Gulbins E. Pharmacological Inhibition of Acid Sphingomyelinase Prevents Uptake of SARS-CoV-2 by Epithelial Cells. Cell Rep Med. 2020 Nov 17;1(8):100142. doi: 10.1016/j.xcrm.2020.100142. Epub 2020 Oct 29.PMID: 33163980

7. Kappe C, Mohamed ZH, Naser E, Carpinteiro A, Arenz A Novel Visible Range FRET Probe for Monitoring Acid Sphingomyelinase Activity in Living Cells.C.Chemistry. 2020 May 7;26(26):5780-5783. doi: 10.1002/chem.202000133. Epub 2020 Apr 21.PMID: 32092185

8. Papathanasiou M, Carpinteiro A, Rischpler C, Hagenacker T, Rassaf T, Luedike P. Diagnosing cardiac amyloidosis in every-day practice: A practical guide for the cardiologist. Int J Cardiol Heart Vasc. 2020 Apr 27;28:100519. doi: 10.1016/j.ijcha.2020.100519. eCollection 2020 Jun.PMID: 32373710

9. Naser E, Kadow S, Schumacher F, Mohamed ZH, Kappe C, Hessler G, Pollmeier B, Kleuser B, Arenz C, Becker KA, Gulbins E, Carpinteiro A. Characterization of the small molecule ARC39, a direct and specific inhibitor of acid sphingomyelinase in vitro.J Lipid Res. 2020 Jun;61(6):896-910. doi: 10.1194/jlr.RA120000682. Epub 2020 Mar 10.PMID: 32156719

10. Carpinteiro A, Becker KA, Gulbins E. Highlight: sphingolipids in infectious biology and immunology. Biol Chem. 2018 Sep 25;399(10):1113. doi: 10.1515/hsz-2018-0341. PubMed PMID: 30138109.

11. Beckmann N, Kadow S, Schumacher F, Göthert JR, Kesper S, Draeger A, Schulz-Schaeffer WJ, Wang J, Becker JU, Kramer M, Kühn C, Kleuser B, Becker KA, Gulbins E, Carpinteiro A. Pathological manifestations of Farber disease in a new mouse model. Biol Chem. 2018 Sep 25;399(10):1183-1202. doi: 10.1515/hsz-2018-0170. PubMed PMID: 29908121.
     
12. Beckmann N, Becker KA, Walter S, Becker JU, Kramer M, Hessler G, Weber S, Göthert JR, Fassbender K, Gulbins E, Carpinteiro A. Regulation of Arthritis Severity by the Acid Sphingomyelinase. Cell Physiol Biochem. 2017;43(4):1460-1471. doi: 10.1159/000481968. Epub 2017 Oct 16. PubMed PMID: 29035882.
     
13. Sydor S, Sowa JP, Megger DA, Schlattjan M, Jafoui S, Wingerter L, Carpinteiro A, Baba HA, Bechmann LP, Sitek B, Gerken G, Gulbins E, Canbay A. Acid sphingomyelinase deficiency in Western diet-fed mice protects against adipocyte hypertrophy and diet-induced liver steatosis. Mol Metab. 2017 Mar 12;6(5):416-427. doi: 10.1016/j.molmet.2017.03.002. eCollection 2017 May. PubMed PMID: 28462076; PubMed Central PMCID: PMC5404101.
     
14. Becker KA, Beckmann N, Adams C, Hessler G, Kramer M, Gulbins E, Carpinteiro A. Melanoma cell metastasis via P-selectin-mediated activation of acid sphingomyelinase in platelets. Clin Exp Metastasis. 2017 Jan;34(1):25-35. doi: 10.1007/s10585-016-9826-6. Epub 2016 Oct 15. PubMed PMID: 27744579.
     
15. Gassa A, Kalkavan H, Jian F, Duhan V, Khairnar V, Shaabani N, Honke N, Carpinteiro A, Botezatu L, Crivello P, Dolff S, Ferencik S, Häussinger D, Khandanpour C, Fleischhauer K, Witzke O, Wahlers T, Hardt C, Lang PA, Lang KS. High Frequencies of Anti-Host Reactive CD8+ T Cells Ignore Non-Hematopoietic Antigen after Bone Marrow Transplantation in a Murine Model. Cell Physiol Biochem. 2016;38(4):1343-53. doi: 10.1159/000443078. Epub 2016 Mar 24. PubMed PMID: 27007114.
     
16. Carpinteiro A, Beckmann N, Seitz A, Hessler G, Wilker B, Soddemann M, Helfrich I, Edelmann B, Gulbins E, Becker KA. Role of Acid Sphingomyelinase-Induced Signaling in Melanoma Cells for Hematogenous Tumor Metastasis. Cell Physiol Biochem. 2016;38(1):1-14. doi: 10.1159/000438604. Epub 2016 Jan 8. PubMed PMID: 26741636.
     
17. Carpinteiro A, Becker KA, Japtok L, Hessler G, Keitsch S, Požgajovà M, Schmid KW, Adams C, Müller S, Kleuser B, Edwards MJ, Grassmé H, Helfrich I, Gulbins E. Regulation of hematogenous tumor metastasis by acid sphingomyelinase. EMBO Mol Med. 2015 Jun;7(6):714-34. doi: 10.15252/emmm.201404571. PubMed PMID: 25851537; PubMed Central PMCID: PMC4459814.
     
18. Managò A, Becker KA, Carpinteiro A, Wilker B, Soddemann M, Seitz AP, Edwards MJ, Grassmé H, Szabò I, Gulbins E. Pseudomonas aeruginosa pyocyanin induces neutrophil death via mitochondrial reactive oxygen species and mitochondrial acid sphingomyelinase. Antioxid Redox Signal. 2015 May 1;22(13):1097-110. doi: 10.1089/ars.2014.5979. Epub 2015 Mar 18. PubMed PMID: 25686490; PubMed Central PMCID: PMC4403017.