Veröffentlichungen
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Diketopiperazine/piperidine alkaloid as a potential broad-spectrum coronaviral entry inhibitor identified by supercomputer-based virtual screening from a large natural product-based libraryIn: Biomedicine & Pharmacotherapy Jg. 183 (2025) 117841Online Volltext: dx.doi.org/ (Open Access)
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Reactivation of latent HIV-1 by the glucocorticoid receptor modulator AZD9567In: Journal of Virology (2025) in pressOnline Volltext: dx.doi.org/ (Open Access)
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Iron improves the antiviral activity of NK cellsIn: Frontiers in Immunology Jg. 15 (2025) 1526197Online Volltext: dx.doi.org/ (Open Access)
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Immunogenicity of the Monovalent Omicron XBB.1.5-Adapted BNT162b2 COVID-19 Vaccine in People Living with HIV (PLWH)In: Vaccines Jg. 12 (2024) Nr. 7, 785Online Volltext: dx.doi.org/ (Open Access)
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Diphyllin elicits a doubled-pronged attack on the entry of SARS-CoV-2 by inhibiting cathepsin L and furinIn: Virus Research Jg. 350 (2024) 199485Online Volltext: dx.doi.org/ (Open Access)
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Macrophage- and CD4+ T cell-derived SIV differ in glycosylation, infectivity and neutralization sensitivityIn: PLoS Pathogens Jg. 20 (2024) Nr. 5, e1012190Online Volltext: dx.doi.org/ (Open Access)
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Persistent low-level viraemia is associated with non-infectious comorbidities in an observational cohort in four African countriesIn: Journal of the International AIDS Society Jg. 27 (2024) Nr. 8, e26316Online Volltext: dx.doi.org/ (Open Access)
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Identification of nitrile-containing isoquinoline-related natural product derivatives as coronavirus entry inhibitors in silico and in vitroIn: Biomedicine & Pharmacotherapy Jg. 180 (2024) 117517Online Volltext: dx.doi.org/ (Open Access)
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T Cell Responses against Orthopoxviruses in HIV-Positive PatientsIn: Vaccines Jg. 12 (2024) Nr. 2, 131Online Volltext: dx.doi.org/ (Open Access)
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An efficient ELISA protocol for measurement of SARS-CoV-2 spike-specific IgG in human plasma and serum samplesIn: MethodsX Jg. 12 (2024) 102596Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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PD-1 knockout on cytotoxic primary murine CD8+ T cells improves their motility in retrovirus infected miceIn: Frontiers in Immunology Jg. 15 (2024) 1338218Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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IFNα Subtypes in HIV Infection and ImmunityIn: Viruses Jg. 16 (2024) Nr. 3, 364Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Multimodal HLA-I genotype regulation by human cytomegalovirus US10 and resulting surface patterningIn: eLife Jg. 13 (2024) e85560Online Volltext: dx.doi.org/ (Open Access)
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Receptor transfer between immune cells by autoantibody-enhanced, CD32-driven trogocytosis is hijacked by HIV-1 to infect resting CD4 T cellsIn: Cell Reports Medicine Jg. 5 (2024) Nr. 4, 101483Online Volltext: dx.doi.org/ (Open Access)
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The Association of HIV-Specific Risk Factors with Cardiovascular Events in Addition to Traditional Risk Factors in People Living with HIVIn: AIDS Research and Human Retroviruses Jg. 40 (2024) Nr. 4, S. 235 - 245Online Volltext: dx.doi.org/
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UnCoVar : A reproducible and scalable workflow for transparent and robust virus variant calling and lineage assignment using SARS-CoV-2 as an exampleIn: BMC Genomics Jg. 25 (2024) Nr. 1, 647Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Fatty acids are crucial to fuel NK cells upon acute retrovirus infectionIn: Frontiers in Immunology Jg. 14 (2023) 1296355Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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High hepatitis B vaccination coverage among a cohort of predominantly men who have sex with men in GermanyIn: Human Vaccines & Immunotherapeutics Jg. 19 (2023) Nr. 2, 2238576Online Volltext: dx.doi.org/ (Open Access)
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Immunotherapy-induced cytotoxic T follicular helper cells reduce numbers of retrovirus-infected reservoir cells in B cell folliclesIn: PLoS Pathogens Jg. 19 (2023) Nr. 10, e1011725Online Volltext: dx.doi.org/ (Open Access)
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Hypoxia-Inducible Factor–Prolyl Hydroxylase Inhibitor Improves Leukocyte Energy Metabolism in Hereditary Hemorrhagic TelangiectasiaIn: Life Jg. 13 (2023) Nr. 8, 1708Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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False-Positive Screening and Confirmatory HIV Diagnostic Test in a Patient with Cured SARS-CoV-2 Infection Is Not Mediated by Env/Spike Cross-Reactive AntibodiesIn: Viruses Jg. 15 (2023) Nr. 5, 1161Online Volltext: dx.doi.org/ (Open Access)
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PLA stereocomplex-chitosan nanoparticles loaded with tenofovir alafenamide as a long-acting antiretroviralsIn: Advanced Powder Technology Jg. 34 (2023) Nr. 11, 104205Online Volltext: dx.doi.org/
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Targeted mutations in IFNα2 improve its antiviral activity against various virusesIn: mBio Jg. 14 (2023) Nr. 6, e02357-23Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Regulatory T cells suppress the motility of cytotoxic T cells in Friend retrovirus-infected miceIn: JCI Insight Jg. 8 (2023) Nr. 13, e167482Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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The hypoxia-regulated ectonucleotidase CD73 is a host determinant of HIV latencyIn: Cell Reports Jg. 42 (2023) Nr. 11, 113285Online Volltext: dx.doi.org/ (Open Access)
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Changes in body mass index, weight, and waist-to-hip ratio over five years in HIV-positive individuals in the HIV Heart Aging Study compared to the general populationIn: Infection - A Journal of Infectious Disease Jg. 51 (2023) Nr. 4, S. 1081 - 1091Online Volltext: dx.doi.org/ (Open Access)
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Preparing for future European efficacy trials of interventions to prevent HIV and other sexually transmitted infections : Lessons on willingness to participate and barriers to participation from ten German clinics serving behaviorally vulnerable men who have sex with menIn: Vaccine: X Jg. 14 (2023) 100302Online Volltext: dx.doi.org/ (Open Access)
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Evolution of functional antibodies following acute Epstein-Barr virus infectionIn: PLoS Pathogens Jg. 18 (2022) Nr. 9, e1010738Online Volltext: dx.doi.org/ (Open Access)
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CCL2 : a Chemokine Potentially Promoting Early Seeding of the Latent HIV ReservoirIn: mBio Jg. 13 (2022) Nr. 5, e0189122Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Dissecting drivers of immune activation in chronic HIV-1 infectionIn: eBioMedicine Jg. 83 (2022) 104182Online Volltext: dx.doi.org/ (Open Access)
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The Bovine Seminal Plasma Protein PDC-109 Possesses Pan-Antiviral ActivityIn: Viruses Jg. 14 (2022) Nr. 9, 2031Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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A Hybrid Soluble gp130/Spike-Nanobody Fusion Protein Simultaneously Blocks Interleukin-6 trans-Signaling and Cellular Infection with SARS-CoV-2In: Journal of Virology Jg. 96 (2022) Nr. 4, e01622-21Online Volltext: dx.doi.org/ (Open Access)
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Distinct Type I Interferon Subtypes Differentially Stimulate T Cell Responses in HIV-1-Infected IndividualsIn: Frontiers in Immunology Jg. 13 (2022) 936918Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Characterization of Hantavirus N Protein Intracellular Dynamics and LocalizationIn: Viruses Jg. 14 (2022) Nr. 3, 457Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Design and Functional Analysis of Heterobifunctional Multivalent Phage Capsid Inhibitors Blocking the Entry of Influenza VirusIn: Bioconjugate Chemistry Jg. 33 (2022) Nr. 7, S. 1269 - 1278Online Volltext: dx.doi.org/ (Open Access)
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Reduction of CD8 T Cell Functionality but Not Inhibitory Capacity by Integrase InhibitorsIn: Journal of Virology Jg. 96 (2022) Nr. 5, e01730-21Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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SARS-CoV-2 antibodies protect against reinfection for at least 6 months in a multicentre seroepidemiological workplace cohortIn: PLoS Biology Jg. 20 (2022) Nr. 2, e3001531Online Volltext: dx.doi.org/ (Open Access)
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Structural and Mechanistic Evidence for Calcium Interacting Sites in the HIV Transmembrane Protein gp41 Involved in Membrane FusionIn: Biochemistry Jg. 61 (2022) Nr. 17, S. 1915 - 1922Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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HIV pre-exposure prophylaxis was associated with no impact on sexually transmitted infection prevalence in a high-prevalence population of predominantly men who have sex with men, Germany, 2018 to 2019In: Eurosurveillance Jg. 27 (2022) Nr. 14, 2100591Online Volltext: dx.doi.org/ (Open Access)
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Discrete SARS-CoV-2 antibody titers track with functional humoral stabilityIn: Nature Communications Jg. 12 (2021) Nr. 1, S. 1018Online Volltext: dx.doi.org/ (Open Access)
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Die HIV-Pandemie : Ein Problem weltweit, auch in DeutschlandIn: Unikate: Berichte aus Forschung und Lehre (2021) Nr. 56 : "Junge Wilde" - Die nächste Generation, S. 40 - 49Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Production of HIV-1 env-specific antibodies mediating innate immune functions depends on cognate interleukin-21-secreting CD4⁺T cellsIn: Journal of Virology Jg. 95 (2021) Nr. 8, S. e02097Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Sofosbuvir Activates EGFR-Dependent Pathways in Hepatoma Cells with Implications for Liver-Related Pathological ProcessesIn: Cells Jg. 9 (2020) Nr. 4, 1003Online Volltext: dx.doi.org/ (Open Access)
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An observational study identifying highly tuberculosis-exposed, HIV-1-positive but persistently TB, tuberculin and IGRA negative persons with M. tuberculosis specific antibodies in Cape Town, South AfricaIn: eBioMedicine Jg. 61 (2020) 103053Online Volltext: dx.doi.org/ (Open Access)
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Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulationsIn: npj Vaccines Jg. 5 (2020) Nr. 1, 72Online Volltext: dx.doi.org/ (Open Access)
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Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathologyIn: PLoS Pathogens Jg. 16 (2020) Nr. 3, e1008340Online Volltext: dx.doi.org/ (Open Access)
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Denken Sie bei HIV-Infizierten auch ans Herz! : Kardiovaskuläre ErkrankungenIn: MMW - Fortschritte der Medizin Jg. 162 (2020) S. 20 - 23Online Volltext: dx.doi.org/
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A high-throughput, bead-based, antigen-specific assay to assess the ability of antibodies to induce complement activationIn: Journal of Immunological Methods Jg. 473 (2019) S. 112630Online Volltext: dx.doi.org/ (Open Access)
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B-type natriuretic peptides for the prediction of cardiovascular events and mortality in patients living with HIV : Results from the HIV-HEART studyIn: International Journal of Cardiology Jg. 281 (2019) S. 127 - 132Online Volltext: dx.doi.org/
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Effect of HIV infection and antiretroviral therapy on immune cellular functionsIn: JCI Insight Jg. 4 (2019) Nr. 12, :e126675Online Volltext: dx.doi.org/ (Open Access)
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Expansion of Stem Cell-Like CD4⁺ Memory T Cells during Acute HIV-1 Infection Is Linked to Rapid Disease ProgressionIn: Journal of Virology Jg. 93 (2019) Nr. 14,Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Sex differences in vaccine-induced humoral immunityIn: Seminars in Immunopathology Jg. 41 (2019) Nr. 2, S. 239 - 249Online Volltext: dx.doi.org/ (Open Access)
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Gut Microbiota in Human Immunodeficiency Virus-Infected Individuals Linked to Coronary Heart DiseaseIn: The Journal of Infectious Diseases (JID) Jg. 219 (2019) Nr. 3, S. 497 - 508Online Volltext: dx.doi.org/ (Open Access)
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Modulation of Vaccine-Induced CD4 T Cell Functional Profiles by Changes in Components of HIV Vaccine Regimens in HumansIn: Journal of Virology Jg. 92 (2018) Nr. 23, S. e01143 - 18Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Transcriptomic signatures of NK cells suggest impaired responsiveness in HIV-1 infection and increased activity post-vaccinationIn: Nature Communications Jg. 9 (2018) Nr. 1, S. 1212Online Volltext: dx.doi.org/ (Open Access)
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Distinct biomarker signatures in HIV acute infection associate with viral dynamics and reservoir sizeIn: JCI Insight Jg. 3 (2018) Nr. 10, e98420Online Volltext: dx.doi.org/ (Open Access)
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Temporal variation in HIV-specific IgG subclass antibodies during acute infection differentiates spontaneous controllers from chronic progressorsIn: AIDS Jg. 32 (2018) Nr. 4, S. 443 - 450Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Antigen-specific antibody Fc glycosylation enhances humoral immunity via the recruitment of complementIn: Science Immunology Jg. 3 (2018) Nr. 26, S. eaat7796Online Volltext: dx.doi.org/ (Open Access)
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Limited immune surveillance in lymphoid tissue by cytolytic CD4+ T cells during health and HIV disease.In: PLoS Pathogens Jg. 14 (2018) Nr. 4, S. e1006973Online Volltext: dx.doi.org/ (Open Access)
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Exploiting glycan topography for computational design of Env glycoprotein antigenicityIn: PLoS Computational Biology Jg. 14 (2018) Nr. 4, S. e1006093Online Volltext: dx.doi.org/ (Open Access)
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Fas Ligand-mediated cytotoxicity of CD4+ T cells during chronic retrovirus infectionIn: Scientific Reports Jg. 7 (2017) S. 7785Online Volltext: dx.doi.org/ (Open Access)
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Preexposure prophylaxis failure with tenofovir disoproxilIn: AIDS Jg. 31 (2017) Nr. 9, S. 1344Online Volltext: dx.doi.org/
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Expression pattern of individual IFNA subtypes in chronic HIV infectionIn: Journal of Interferon & Cytokine Research Jg. 37 (2017) Nr. 12, S. 541 - 549Online Volltext: dx.doi.org/
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Pre-exposure prophylaxis failure with tenofovir disoproxilIn: AIDS Jg. 31 (2017) Nr. 1, S. 176 - 177Online Volltext: dx.doi.org/
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Preservation of peripheral T follicular helper cell function in HIV controllersIn: Journal of Virology Jg. 91 (2017) Nr. 14, S. e00497 - 17Online Volltext: dx.doi.org/ (Open Access)
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Differential inhibitory receptor expression on T cells delineates functional capacities in chronic viral infectionIn: Journal of Virology Jg. 91 (2017) Nr. 23, S. e01263 - 17Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Antigen-Specific Antibody Glycosylation Is Regulated via VaccinationIn: PLoS Pathogens Jg. 12 (2016) Nr. 3, S. e1005456Online Volltext: dx.doi.org/ (Open Access)
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Designing optimal HIV-vaccine T-cell responsesIn: Current Opinion in HIV and AIDS Jg. 11 (2016) Nr. 6, S. 593 - 600Online Volltext: dx.doi.org/
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Barriers to HIV CureIn: HLA: Immune Response Genetics (Human Leukocyte Antigens) Jg. 88 (2016) Nr. 4, S. 155 - 163Online Volltext: dx.doi.org/
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CD137 agonist therapy can reprogram regulatory T cells into cytotoxic CD4+ T cells with antitumor activityIn: The Journal of Immunology (JI) Jg. 196 (2016) Nr. 1, S. 484 - 492Online Volltext: dx.doi.org/ (Open Access)
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A Functional Role for Antibodies in TuberculosisIn: Cell Jg. 167 (2016) Nr. 2, S. 433 - 443.e14Online Volltext: dx.doi.org/ (Open Access)
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Enhanced binding of antibodies generated during chronic HIV infection to mucus component MUC16In: Mucosal Immunology Jg. 9 (2016) Nr. 6, S. 1549 - 1558Online Volltext: dx.doi.org/
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Antiviral CD8(+) T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal ExpansionIn: Immunity Jg. 45 (2016) Nr. 4, S. 917 - 930Online Volltext: dx.doi.org/ (Open Access)
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Fc receptor-mediated phagocytosis in tissues as a potent mechanism for preventive and therapeutic HIV vaccine strategiesIn: Mucosal Immunology Jg. 9 (2016) Nr. 6, S. 1584 - 1595Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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TGF-β receptor maintains CD4 T helper cell identity during chronic viral infectionsIn: The Journal of Clinical Investigation (JCI) Jg. 126 (2016) Nr. 10, S. 3799 - 3813Online Volltext: dx.doi.org/
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Subdominant Gag-specific anti-HIV efficacy in an HLA-B*57-positive elite controllerIn: AIDS Jg. 30 (2016) Nr. 6, S. 972 - 974Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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AIDS virus seeks refuge in B cell folliclesIn: Nature Medicine Jg. 21 (2015) Nr. 2, S. 111 - 112Online Volltext: dx.doi.org/
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Dissecting Polyclonal Vaccine-Induced Humoral Immunity against HIV Using Systems SerologyIn: Cell Jg. 163 (2015) Nr. 4, S. 988 - 998Online Volltext: dx.doi.org/ (Open Access)
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IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infectionIn: Nature Communications Jg. 6 (2015) S. 7562Online Volltext: dx.doi.org/ (Open Access)
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Cooperativity of HIV-Specific Cytolytic CD4 T Cells and CD8 T Cells in Control of HIV ViremiaIn: Journal of Virology Jg. 89 (2015) Nr. 15, S. 7494 - 7505Online Volltext: dx.doi.org/ (Open Access)
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HIV-specific TFH cells induced by vaccination and natural infectionIn: Journal of Medical Primatology Jg. 44 (2015) Nr. 5, Special Issue: 32nd Annual Symposium on Nonhuman Primate Models for AIDS, S. 321Online Volltext: dx.doi.org/