IMB: AG Becker-Flegler
Group Becker-Flegler Research Interests
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Role of sphingolipids in infection and inflammation
Sphingolipids in cystic fibrosis
Sphingolipids as target molecules during bacterial and viral infections, especially infections with Staphylococcus aureus, Pseudomonas aeruginosa and SARS-CoV-2
Bactericidal effect of sphingosine
Molecular mechanism how hypoxia contributes to reduced sphingosine levels in infected lungs
Sphingosine coating of endo-implants to fight against peri-implant infections
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Role of sphingolipids in tumor therapy
Role of tumor-host sphingolipids in response to tumor therapy
Role of the acid ceramidase and the acid sphingomyelinase within tumor therapy
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Inhibition of the mitochondrial Kv1.3 channel in cancer treatment