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Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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PDCD10 Is a Key Player in TMZ-Resistance and Tumor Cell Regrowth : Insights into Its Underlying Mechanism in Glioblastoma CellsIn: Cells Jg. 13 (2024) Nr. 17, 1442Online Volltext: dx.doi.org/ (Open Access)
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Effects of medication intake on the risk of hemorrhage in patients with sporadic cerebral cavernous malformationsIn: Frontiers in Neurology Jg. 13 (2023) 1010170Online Volltext: dx.doi.org/ (Open Access)
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Novel Function of Cancer Stem Cell Marker ALDH1A3 in Glioblastoma : Pro-Angiogenesis through Paracrine PAI-1 and IL-8In: Cancers Jg. 15 (2023) Nr. 17, 4422Online Volltext: dx.doi.org/ (Open Access)
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Cavernous Malformations : Updates in Surgical Management and BiologyIn: Neurosurgery Clinics of North America Jg. 33 (2022) Nr. 4, S. 449 - 460Online Volltext: dx.doi.org/
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Cerebral cavernous malformations do not fall in the spectrum of PIK3CA-related overgrowthIn: Journal of Neurology, Neurosurgery and Psychiatry Jg. 93 (2022) Nr. 8, S. 808 - 815Online Volltext: dx.doi.org/
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Characterization of Temozolomide Resistance Using a Novel Acquired Resistance Model in Glioblastoma Cell LinesIn: Cancers Jg. 14 (2022) Nr. 9, 2211Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Ischemia-induced inflammation in arteriovenous malformationsIn: Neurosurgical Focus Jg. 53 (2022) Nr. 1, E3Online Volltext: dx.doi.org/ (Open Access)
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Medication intake and hemorrhage risk in patients with familial cerebral cavernous malformationsIn: Journal of Neurosurgery (JNS) Jg. 137 (2022) Nr. 4, S. 1088 - 1094Online Volltext: dx.doi.org/ (Open Access)
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Multiple cerebral cavernous malformations : Clinical course of confirmed, assumed and non‐familial diseaseIn: European Journal of Neurology Jg. 29 (2022) Nr. 5, S. 1427 - 1434Online Volltext: dx.doi.org/ (Open Access)
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PDCD10 promotes the aggressive behaviors of pituitary adenomas by up-regulating CXCR2 and activating downstream AKT/ERK signalingIn: Aging Jg. 14 (2022) Nr. 15, S. 6066 - 6080Online Volltext: dx.doi.org/ (Open Access)
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Cerebral cavernous malformations : Prevalence of cardiovascular comorbidities and allergic diseases compared to the normal populationIn: European Journal of Neurology Jg. 28 (2021) Nr. 6, S. 2000 - 2005Online Volltext: dx.doi.org/ (Open Access)
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Health-related quality of life in patients with untreated cavernous malformations of the central nervous systemIn: European Journal of Neurology Jg. 28 (2021) Nr. 2, S. 491 - 499Online Volltext: dx.doi.org/ (Open Access)
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Modifiable Cardiovascular Risk Factors in Patients With Sporadic Cerebral Cavernous Malformations : Obesity MattersIn: Stroke Jg. 52 (2021) Nr. 4, S. 1259 - 1264Online Volltext: dx.doi.org/ (Open Access)
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DNA promoter methylation of CCM genes in human cerebral cavernous malformations : Importance of confirming MSP data through sequencingIn: European Journal of Medical Genetics (EJMG) Jg. 63 (2020) Nr. 12, 104090Online Volltext: dx.doi.org/
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Hemorrhage from cerebral cavernous malformations: The role of associated developmental venous anomaliesIn: Neurology Jg. 95 (2020) Nr. 1, S. e89 - e96Online Volltext: dx.doi.org/
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PDCD10-Deficiency Promotes Malignant Behaviors and Tumor Growth via Triggering EphB4 Kinase Activity in GlioblastomaIn: Frontiers in Oncology Jg. 10 (2020) S. 1377Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Pathophysiology of Intracranial Aneurysms : COX-2 Expression, Iron Deposition in Aneurysm Wall, and Correlation With Magnetic Resonance ImagingIn: Stroke Jg. 51 (2020) Nr. 8, S. 2505 - 2513Online Volltext: dx.doi.org/ (Open Access)
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TET2 promotor methylation and TET2 protein expression in pediatric posterior fossa ependymomaIn: Neuropathology Jg. 40 (2020) Nr. 2, S. 138 - 143Online Volltext: dx.doi.org/ (Open Access)
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The predominant expression of cancer stem cell marker ALDH1A3 in tumor infiltrative area is associated with shorter overall survival of human glioblastomaIn: BMC Cancer Jg. 20 (2020) Nr. 1, 672Online Volltext: dx.doi.org/ (Open Access)
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Loss of programmed cell death 10 activates tumor cells and leads to temozolomide-resistance in glioblastomaIn: Journal of Neuro-Oncology Jg. 141 (2019) Nr. 1, S. 31 - 41Online Volltext: dx.doi.org/
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Correlation of the venous angioarchitecture of multiple cerebral cavernous malformations with familial or sporadic disease : A susceptibility-weighted imaging study with 7-Tesla MRIIn: Journal of Neurosurgery (JNS) Jg. 126 (2017) Nr. 2, S. 570 - 577Online Volltext: dx.doi.org/
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EphB4 forward signalling mediates angiogenesis caused by CCM3/PDCD10-ablationIn: Journal of Cellular and Molecular Medicine Jg. 21 (2017) Nr. 9, S. 1848 - 1858Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Outcome after conservative management or surgical treatment for new-onset epilepsy in cerebral cavernous malformationIn: Journal of Neurosurgery (JNS) Jg. 126 (2017) Nr. 4, S. 1303 - 1311Online Volltext: dx.doi.org/
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Study of angiogenic signaling pathways in hemangioblastomaIn: Neuropathology Jg. 37 (2017) Nr. 1, S. 3 - 11Online Volltext: dx.doi.org/
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Activation of multiple angiogenic signaling pathways in hemangiopericytomaIn: Brain Tumor Pathology Jg. 33 (2016) Nr. 3, S. 200 - 208Online Volltext: dx.doi.org/
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Loss of endothelial programmed cell death 10 activates glioblastoma cells and promotes tumor growthIn: Neuro-Oncology Jg. 18 (2016) Nr. 4, S. 538 - 548Online Volltext: dx.doi.org/ (Open Access)
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Multiple cerebral arterio-venous malformations : impact of multiplicity and hemodynamics on treatment strategiesIn: Acta Neurochirurgica Jg. 158 (2016) Nr. 12, S. 2399 - 2407Online Volltext: dx.doi.org/
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Solitary Sporadic Cerebral Cavernous Malformations: Risk Factors of First or Recurrent Symptomatic Hemorrhage and Associated Functional ImpairmentIn: World Neurosurgery Jg. 91 (2016) S. 73 - 80Online Volltext: dx.doi.org/
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Associated aneurysms in supratentorial arteriovenous malformations : impact of aneurysm size on haemorrhageIn: Cerebrovascular Diseases Jg. 39 (2015) Nr. 2, S. 122 - 129Online Volltext: dx.doi.org/
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Comments: PTEN/PI3K/Akt/VEGF signaling and the cross talk to KRIT1, CCM2, and PDCD10 proteins in cerebral cavernous malformationsIn: Neurosurgical Review Jg. 38 (2015) Nr. 2, S. 236 - 237Online Volltext: dx.doi.org/
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Downregulation of programmed cell death 10 is associated with tumor cell proliferation, hyperangiogenesis and peritumoral edema in human glioblastomaIn: BMC Cancer Jg. 15 (2015) S. 759 - 770Online Volltext: dx.doi.org/ (Open Access)
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Regulation of β1 integrin-Klf2-mediated angiogenesis by CCM proteinsIn: Developmental Cell Jg. 32 (2015) Nr. 2, S. 181 - 190Online Volltext: dx.doi.org/ (Open Access)
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Posterior fossa arterio-venous malformations : current multimodal treatment strategies and resultsIn: Neurosurgical Review Jg. 37 (2014) Nr. 4, S. 619 - 628Online Volltext: dx.doi.org/
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Correlation of Aquaporin-1 Water Channel Protein Expression with Tumor Angiogenesis in Human AstrocytomaIn: Anticancer Research Jg. 33 (2013) Nr. 2, S. 609 - 613
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Implications of Dll4-Notch signaling activation in primary glioblastoma multiformeIn: Neuro-Oncology Jg. 15 (2013) Nr. 10, S. 1366 - 1378Online Volltext: dx.doi.org/
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Loss of CCM3 impairs DLL4-Notch signalling: implication in endothelial angiogenesis and in inherited cerebral cavernous malformationsIn: Journal of Cellular and Molecular Medicine Jg. 17 (2013) Nr. 3, S. 407 - 418Online Volltext: dx.doi.org/
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The functional Aquaporin 1 −783G/C-polymorphism is associated with survival in patients with glioblastoma multiformeIn: Journal of Surgical Oncology Jg. 108 (2013) Nr. 7, S. 492 - 498Online Volltext: dx.doi.org/
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The venous angioarchitecture of sporadic cerebral cavernous malformations : a susceptibility weighted imaging study at 7 T MRIIn: Journal of Neurology, Neurosurgery and Psychiatry Jg. 84 (2013) Nr. 2, S. 194 - 201Online Volltext: dx.doi.org/
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Two-hit mechanism in cerebral cavernous malformation? A case of monozygotic twins with a CCM1/KRIT1 germline mutationIn: Neurosurgical Review Jg. 36 (2013) Nr. 3, S. 483 - 486Online Volltext: dx.doi.org/
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Association of the CC genotype of the regulatory BCL2 promoter polymorphism (−938C>A) with better 2-year survival in patients with glioblastoma multiformeIn: Journal of Neurosurgery (JNS) Jg. 114 (2011) Nr. 6, S. 1631 - 1639Online Volltext: dx.doi.org/
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In vitro characterization of the angiogenic phenotype and genotype of the endothelia derived from sporadic cerebral cavernous malformationsIn: Neurosurgery Jg. 69 (2011) Nr. 3, S. 722 - 732Online Volltext: dx.doi.org/
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Role of the GNAS1 T393C polymorphism in patients with glioblastoma multiformeIn: Journal of Clinical Neuroscience Jg. 18 (2011) Nr. 11, S. 1495 - 1499Online Volltext: dx.doi.org/
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Cerebral cavernous malformation protein CCM1 inhibits sprouting angiogenesis by activating DELTA-NOTCH signalingIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 107 (2010) Nr. 28, S. 12640 - 12645Online Volltext: dx.doi.org/
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Differential angiogenesis function of CCM2 and CCM3 in cerebral cavernous malformationsIn: Neurosurgical Focus Jg. 29 (2010) Nr. 3, S. E1Online Volltext: dx.doi.org/
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Proliferation activity is significantly elevated in partially embolized cerebral arteriovenous malformationsIn: Cerebrovascular Diseases Jg. 30 (2010) Nr. 4, S. 396 - 401Online Volltext: dx.doi.org/
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Susceptibility weighted magnetic resonance imaging of cerebral cavernous malformations : prospects, drawbacks, and first experience at ultra–high field strength (7-Tesla) magnetic resonance imagingIn: Neurosurgical Focus Jg. 29 (2010) Nr. 3, S. E5Online Volltext: dx.doi.org/
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Involvement of PTEN Promoter Methylation in Cerebral Cavernous MalformationsIn: Stroke Jg. 40 (2009) Nr. 3, S. 820 - 826Online Volltext: dx.doi.org/
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Phosphatase and tensin homolog in cerebral cavernous malformation : a potential role in pathological angiogenesisIn: Journal of Neurosurgery (JNS) Jg. 110 (2009) Nr. 3, S. 530 - 539Online Volltext: dx.doi.org/
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Increased expression of EphA2 correlates with adverse outcome in primary and recurrent glioblastoma multiforme patientsIn: Oncology reports Jg. 19 (2008) Nr. 1, S. 151 - 156Online Volltext: dx.doi.org/
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Implication of PTEN in production of reactive oxygen species and neuronal death in in vitro models of stroke and Parkinson's diseaseIn: Neurochemistry international Jg. 50 (2007) Nr. 3, S. 507 - 516Online Volltext: dx.doi.org/
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Biological activity of paediatric cerebral cavernomas : an immunohistochemical study of 28 patientsIn: Child's nervous system Jg. 22 (2006) Nr. 7, S. 685 - 691Online Volltext: dx.doi.org/
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PTEN : A crucial mediator of mitochondria-dependent apoptosisIn: Apoptosis : an international journal on programmed cell death Jg. 11 (2006) Nr. 2, S. 197 - 207Online Volltext: dx.doi.org/
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Oleic acid causes apoptosis and dephosphorylates BadIn: Neurochemistry international Jg. 46 (2005) Nr. 2, S. 127 - 135Online Volltext: dx.doi.org/
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Unsaturated fatty acids isolated from human lipoproteins activate protein phosphatase type 2Cβ and induce apoptosis in endothelial cellsIn: Atherosclerosis Jg. 180 (2005) Nr. 2, S. 245 - 254Online Volltext: dx.doi.org/
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Neuroprotection by transforming growth factor-β1 involves activation of nuclear factor-κB through phosphatidylinositol-3-OH kinase/Akt and mitogen-activated protein kinase-extracellular-signal regulated kinase1,2 signaling pathwaysIn: Neuroscience Jg. 123 (2004) Nr. 4, S. 897 - 906Online Volltext: dx.doi.org/
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Protein kinase CK2 phosphorylates BAD at threonine-117In: Neurochemistry international Jg. 45 (2004) Nr. 5, S. 747 - 752Online Volltext: dx.doi.org/
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Cytosine arabinofuranoside-induced activation of astrocytes increases the susceptibility of neurons to glutamate due to the release of soluble factorsIn: Neurochemistry international Jg. 42 (2003) Nr. 7, S. 567 - 581Online Volltext: dx.doi.org/
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Neuroprotection by drug-induced growth factorsIn: International congress series : ICS Jg. 1252 (2003) S. 235 - 246Online Volltext: dx.doi.org/
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Increase in glutamate-induced neurotoxicity by activated astrocytes involves stimulation of protein kinase CIn: Journal of neurochemistry Jg. 82 (2002) Nr. 3, S. 504 - 515Online Volltext: dx.doi.org/
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Transforming Growth Factor-β1 Increases Bad Phosphorylation and Protects Neurons Against DamageIn: The Journal of Neuroscience Jg. 22 (2002) Nr. 10, S. 3898 - 3909
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Evidence for the involvement of Par-4 in ischemic neuron cell deathIn: Journal of Cerebral Blood Flow and Metabolism (JCBFM) Jg. 21 (2001) Nr. 4, S. 334 - 343Online Volltext: dx.doi.org/
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TGF-β1 inhibits caspase-3 activation and neuronal apoptosis in rat hippocampal culturesIn: Neurochemistry international Jg. 38 (2001) Nr. 3, S. 227 - 235Online Volltext: dx.doi.org/
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β2-Adrenoceptor stimulation enhances latent transforming growth factor-β-binding protein-1 and transforming growth factor-β1 expression in rat hippocampus after transient forebrain ischemiaIn: Neuroscience: IBRO, International Brain Research Organization Jg. 107 (2001) Nr. 4, S. 593 - 602Online Volltext: dx.doi.org/
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Stimulation of 5-HT1A receptors reduces apoptosis after transient forebrain ischemia in the ratIn: Brain research Jg. 883 (2000) Nr. 1, S. 41 - 50Online Volltext: dx.doi.org/
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The expression of transforming growth factor-beta1 (TGF-β1) in hippocampal neurons : a temporary upregulated protein level after transient forebrain ischemia in the ratIn: Brain research Jg. 866 (2000) Nr. 1-2, S. 286 - 298Online Volltext: dx.doi.org/
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The β2-adrenoceptor agonist clenbuterol modulates Bcl-2, Bcl-xl and Bax protein expression following transient forebrain ischemiaIn: Neuroscience Jg. 90 (1999) Nr. 4, S. 1255 - 1263Online Volltext: dx.doi.org/
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β2-Adrenoceptor Agonist Clenbuterol Causes NGF Expression and NeuroprotectionIn: CNS drug reviews Jg. 5 (1999) Nr. 4, S. 347 - 364Online Volltext: dx.doi.org/
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Lanzino G, Spetzler RF (Eds), Cavernous malformations of the brain and spinal cordIn: Neurosurgical Review Jg. 33 (2010) Nr. 2, S. 255 - 255Online Volltext: dx.doi.org/
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Activation of NF-kB by TGF-ß1 through PI3K/Akt and MAPK/Erk1,2 signalling pathwaysIn: Pharmacology of cerebral ischemia / International Symposium on Pharmacology of Cerebral Ischemia <10, 2004, Marburg> / Krieglstein, Josef (Hrsg.) 2004, S. 397 - 405
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Mechanisms of neuroprotection by THFβ1In: Pharmacology of cerebral ischemia 2002: with 35 tables / 9th International Symposium on Pharmacology of Cerebral Ischemia, 2002, Marburg / Krieglstein, Josef (Hrsg.) 2002, S. 363 - 371
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The novel molecular pathomechanism of cerebral cavernous malformations (CCMs)Duisburg, Essen (2011) CD-ROM