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Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Panitumumab plus 5-fluorouracil and folinic acid or 5-fluorouracil and folinic acid alone as maintenance therapy in RAS wild-type metastatic colorectal cancer (PanaMa, AIO KRK 0212) : final efficacy analysis of a randomised, open-label, phase 2 trialIn: eClinicalMedicine Jg. 79 (2025) 103004Online Volltext: dx.doi.org/ (Open Access)
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Applicability of a digital health application for cancer patients : A qualitative non-participation analysisIn: BMC Health Services Research Jg. 24 (2024) Nr. 1, 1187Online Volltext: dx.doi.org/ (Open Access)
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Cetuximab Every 2 Weeks Versus Standard Weekly Dosing Administration ScheduleIn: Future Oncology Jg. 20 (2024) Nr. 7, S. 393 - 407Online Volltext: dx.doi.org/ (Open Access)
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Comprehensive biomarker diagnostics of unfavorable cancer of unknown primary to identify patients eligible for precision medical therapiesIn: European Journal of Cancer (EJC) Jg. 200 (2024) 113540Online Volltext: dx.doi.org/ (Open Access)
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Current use of percutaneous image-guided tumor ablation for the therapy of liver tumors : Lessons learned from the registry of the German Society for Interventional Radiology and Minimally Invasive Therapy (DeGIR) 2018–2022In: European Radiology Jg. 34 (2024) Nr. 5, S. 3322 - 3330Online Volltext: dx.doi.org/ (Open Access)
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Dermatology-related quality-of-life outcomes in patients with RAS wild-type metastatic colorectal cancer treated with fluorouracil and folinic acid with or without panitumumab (Pmab) maintenance after FOLFOX + Pmab induction : A prespecified secondary analysis of the phase II randomized PanaMa (AIO KRK 0212) trialIn: ESMO Open Jg. 9 (2024) Nr. 7, 103628Online Volltext: dx.doi.org/ (Open Access)
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Diagnostic Accuracy of ⁶⁸Ga-FAPI Versus ¹⁸F-FDG PET in Patients with Various MalignanciesIn: Journal of Nuclear Medicine (JNM) Jg. 65 (2024) Nr. 3, S. 372 - 378Online Volltext: dx.doi.org/ (Open Access)
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Exploring the impact of durvalumab on biliary tract cancer : insights from real-world clinical dataIn: Cancer Immunology, Immunotherapy Jg. 73 (2024) Nr. 12, S. 251Online Volltext: dx.doi.org/ (Open Access)
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Head-to-head comparison of ⁶⁸ Ga-FAPI-46 PET/CT, ¹⁸F-FDG PET/CT, and contrast-enhanced CT for the detection of various tumorsIn: Annals of Nuclear Medicine (2024) in pressOnline Volltext: dx.doi.org/
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Negative Hyperselection of Resistance Mutations for Panitumumab Maintenance in RAS Wild-Type Metastatic Colorectal Cancer (PanaMa Phase II Trial, AIO KRK 0212)In: Clinical Cancer Research Jg. 30 (2024) Nr. 7, S. 1256 - 1263Online Volltext: dx.doi.org/
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P-move : A randomized control trial of exercise in patients with advanced pancreatic or biliary tract cancer (aPBC) receiving beyond first-line chemotherapyIn: Supportive Care in Cancer Jg. 32 (2024) Nr. 7, 437Online Volltext: dx.doi.org/ (Open Access)
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PD-L1 expression associates with favorable survival of patients with cancer of unknown primary (CUP) not treated with checkpoint inhibitorsIn: European Journal of Cancer (EJC) Jg. 210 (2024) 114268Online Volltext: dx.doi.org/ (Open Access)
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Prognostic Implications of ⁶⁸Ga-FAPI-46 PET/CT-Derived Parameters on Overall Survival in Various Types of Solid TumorsIn: Journal of Nuclear Medicine (JNM) Jg. 65 (2024) Nr. 7, S. 1027 - 1034Online Volltext: dx.doi.org/
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Prognostic and predictive impact of metastatic organ involvement on maintenance therapy in advanced metastatic colorectal cancer : Subgroup analysis of patients treated within the PanaMa trial (AIO KRK 0212)In: International Journal of Cancer Jg. 154 (2024) Nr. 5, S. 863 - 872Online Volltext: dx.doi.org/ (Open Access)
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Prognostic value of deep learning-derived body composition in advanced pancreatic cancer : A retrospective multicenter studyIn: ESMO Open Jg. 9 (2024) Nr. 1, 102219Online Volltext: dx.doi.org/ (Open Access)
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Understanding homologous recombination repair deficiency in biliary tract cancers : clinical implications and correlation with platinum sensitivityIn: ESMO Open Jg. 9 (2024) Nr. 8, 103630Online Volltext: dx.doi.org/ (Open Access)
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A Phase II Study of Nab-Paclitaxel and Gemcitabine as First-Line Therapy in Patients with Cholangiocarcinoma Ineligible for Cisplatin-Based Chemotherapy (NACHO)In: Oncology Research and Treatment Jg. 46 (2023) Nr. 3, S. 89 - 99Online Volltext: dx.doi.org/ (Open Access)
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A prognostic systemic inflammation score (SIS) in patients with advanced intrahepatic cholangiocarcinomaIn: Journal of Cancer Research and Clinical Oncology Jg. 149 (2023) Nr. 8, S. 5085 - 5094Online Volltext: dx.doi.org/ (Open Access)
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Clinical Outcome and Treatment Sequences of Patients with Advanced Pancreatic Cancer Treated with Contemporary Chemotherapy ProtocolsIn: Oncology Research and Treatment Jg. 46 (2023) Nr. 4, S. 140 - 150Online Volltext: dx.doi.org/
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Combination of the STING Agonist MIW815 (ADU-S100) and PD-1 Inhibitor Spartalizumab in Advanced/Metastatic Solid Tumors or Lymphomas : An Open-Label, Multicenter, Phase Ib StudyIn: Clinical Cancer Research Jg. 29 (2023) Nr. 1, S. 110 - 121Online Volltext: dx.doi.org/
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Consensus Molecular Subtypes as Biomarkers of Fluorouracil and Folinic Acid Maintenance Therapy With or Without Panitumumab in RAS Wild-Type Metastatic Colorectal Cancer (PanaMa, AIO KRK 0212)In: Journal of Clinical Oncology (JCO) Jg. 41 (2023) Nr. 16, S. 2975 - 2987Online Volltext: dx.doi.org/
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Deep learning-based assessment of body composition and liver tumour burden for survival modelling in advanced colorectal cancerIn: Journal of Cachexia, Sarcopenia and Muscle Jg. 14 (2023) Nr. 1, S. 545 - 552Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Depth of response of induction therapy and consecutive maintenance treatment in patients with RAS wild-type metastatic colorectal cancer : An analysis of the PanaMa trial (AIO KRK 0212)In: European Journal of Cancer (EJC) Jg. 178 (2023) S. 37 - 48Online Volltext: dx.doi.org/
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Durvalumab with or without tremelimumab versus the EXTREME regimen as first-line treatment for recurrent or metastatic squamous cell carcinoma of the head and neck : KESTREL, a randomized, open-label, phase III studyIn: Annals of Oncology Jg. 34 (2023) Nr. 3, S. 262 - 274Online Volltext: dx.doi.org/ (Open Access)
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FOLFOXIRI Plus Cetuximab or Bevacizumab as First-Line Treatment of BRAF V⁶⁰⁰E-Mutant Metastatic Colorectal Cancer : The Randomized Phase II FIRE-4.5 (AIO KRK0116) StudyIn: Journal of Clinical Oncology (JCO) Jg. 41 (2023) Nr. 25, S. 4143 - 4153Online Volltext: dx.doi.org/ (Open Access)
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Favorable survival outcomes in epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer sequentially treated with a tyrosine kinase inhibitor and osimertinib in a real-world settingIn: Journal of Cancer Research and Clinical Oncology Jg. 149 (2023) Nr. 11, S. 9243 - 9252Online Volltext: dx.doi.org/ (Open Access)
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Fibroblast-Activation Protein PET and Histopathology in a Single-Center Database of 324 Patients and 21 Tumor EntitiesIn: Journal of Nuclear Medicine (JNM) Jg. 64 (2023) Nr. 5, S. 711 - 716Online Volltext: dx.doi.org/ (Open Access)
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Fruquintinib versus placebo in patients with refractory metastatic colorectal cancer (FRESCO-2) : an international, multicentre, randomised, double-blind, phase 3 studyIn: Lancet Jg. 402 (2023) Nr. 10395, S. 41 - 53Online Volltext: dx.doi.org/
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Health-related quality of life in patients with RAS wild-type metastatic colorectal cancer treated with fluorouracil and folinic acid with or without panitumumab as maintenance therapy : A prespecified secondary analysis of the PanaMa (AIO KRK 0212) trialIn: European Journal of Cancer (EJC) Jg. 190 (2023) 112955Online Volltext: dx.doi.org/
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Identification of a new prognostic score for patients with high-grade metastatic GEP-NEN treated with palliative chemotherapyIn: Journal of Cancer Research and Clinical Oncology Jg. 149 (2023) Nr. 8, S. 4315 - 4325Online Volltext: dx.doi.org/ (Open Access)
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Impact of encorafenib on survival of patients with BRAFV⁶⁰⁰E-mutant metastatic colorectal cancer in a real-world settingIn: Journal of Cancer Research and Clinical Oncology Jg. 149 (2023) Nr. 14, S. 12903 - 12912Online Volltext: dx.doi.org/ (Open Access)
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New Prognostic Score (Essen Score) to Predict Postoperative Morbidity after Resection of Lung MetastasesIn: Cancers Jg. 15 (2023) Nr. 17, 4355Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Overall survival with cetuximab every-2-weeks versus standard once-weekly administration schedule for first-line treatment of RAS wild-type metastatic colorectal cancer in patients with left- and right-sided primary tumour locationIn: European Journal of Cancer (EJC) Jg. 180 (2023) S. 85 - 88Online Volltext: dx.doi.org/
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PSMA-Directed Imaging and Therapy of Salivary Gland Tumors : A Single-Center Retrospective StudyIn: Journal of Nuclear Medicine (JNM) Jg. 64 (2023) Nr. 3, S. 372 - 378Online Volltext: dx.doi.org/ (Open Access)
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Phase Ib/II Study of the Efficacy and Safety of Binimetinib (MEK162) Plus Panitumumab for Mutant or Wild-Type RAS Metastatic Colorectal CancerIn: The Oncologist Jg. 28 (2023) Nr. 12, S. e1209 - e1218Online Volltext: dx.doi.org/ (Open Access)
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Real-Life Experience in the Treatment of Intrahepatic Cholangiocarcinoma by ⁹⁰Y Radioembolization : A Multicenter Retrospective StudyIn: Journal of Nuclear Medicine (JNM) Jg. 64 (2023) Nr. 4, S. 529 - 535Online Volltext: dx.doi.org/ (Open Access)
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SUVmₐₓ Above 20 in ¹⁸F-FDG PET/CT at Initial Diagnostic Workup Associates with Favorable Survival in Patients with Cancer of Unknown PrimaryIn: Journal of Nuclear Medicine (JNM) Jg. 64 (2023) Nr. 8, S. 1191 - 1194Online Volltext: dx.doi.org/ (Open Access)
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Smaller panel, similar results : Genomic profiling and molecularly informed therapy in pancreatic cancerIn: ESMO Open Jg. 8 (2023) Nr. 3, 101539Online Volltext: dx.doi.org/ (Open Access)
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Superior Tumor Detection for ⁶⁸Ga-FAPI-46 Versus ¹⁸F-FDG PET/CT and Conventional CT in Patients with CholangiocarcinomaIn: Journal of Nuclear Medicine (JNM) Jg. 64 (2023) Nr. 7, S. 1049 - 1055Online Volltext: dx.doi.org/ (Open Access)
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Arbeitsgruppen zu kolorektalen Tumoren der AIO, der ACO und der ARO – „past, present, and future“In: Der Onkologe Jg. 28 (2022) Nr. Suppl. 1, S. 44 - 49Online Volltext: dx.doi.org/
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FOLFOX plus panitumumab or FOLFOX alone as additive therapy following R0/1 resection of RAS wild-type colorectal cancer liver metastases : The PARLIM trial (AIO KRK 0314)In: European Journal of Cancer (EJC) Jg. 173 (2022) S. 297 - 306Online Volltext: dx.doi.org/
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Heilung ohne Operation und Radiochemotherapie beim lokal fortgeschrittenen, Mismatch-Reparatur-defizienten Rektumkarzinom?In: Coloproctology Jg. 44 (2022) Nr. 5, S. 357 - 360Online Volltext: dx.doi.org/
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Long-term Outcomes with Nivolumab as First-line Treatment in Recurrent or Metastatic Head and Neck Cancer : Subgroup Analysis of CheckMate 141In: The Oncologist Jg. 27 (2022) Nr. 2, S. e194 - e198Online Volltext: dx.doi.org/ (Open Access)
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Multimodal survival prediction in advanced pancreatic cancer using machine learningIn: ESMO Open Jg. 7 (2022) Nr. 5, 100555Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Neue Therapieoption bei lokal fortgeschrittenem dMMR/MSIhigh RektumkarzinomIn: Die Innere Medizin Jg. 63 (2022) Nr. 11, S. 1213 - 1216Online Volltext: dx.doi.org/
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PET-directed combined modality therapy for gastroesophageal junction cancer : Results of the multicentre prospective MEMORI trial of the German Cancer Consortium (DKTK)In: European Journal of Cancer (EJC) Jg. 175 (2022) S. 99 - 106Online Volltext: dx.doi.org/
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Panitumumab Plus Fluorouracil and Folinic Acid Versus Fluorouracil and Folinic Acid Alone as Maintenance Therapy in RAS Wild-Type Metastatic Colorectal Cancer : The Randomized PANAMA Trial (AIO KRK 0212)In: Journal of Clinical Oncology (JCO) Jg. 40 (2022) Nr. 1, S. 72 - 82Online Volltext: dx.doi.org/ (Open Access)
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Photochemical Internalization of Gemcitabine Is Safe and Effective in Locally Advanced Inoperable CholangiocarcinomaIn: The Oncologist Jg. 27 (2022) Nr. 6, S. 430 - 431, e423 - e433Online Volltext: dx.doi.org/ (Open Access)
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Serial Analysis of Gene Mutations and Gene Expression during First-Line Chemotherapy against Metastatic Colorectal Cancer : Identification of Potentially Actionable Targets within the Multicenter Prospective Biomarker Study REVEALIn: Cancers Jg. 14 (2022) Nr. 15, 3631Online Volltext: dx.doi.org/ (Open Access)
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Survival after secondary liver resection in metastatic colorectal cancer : Comparing data of three prospective randomized European trials ( LICC , CELIM , FIRE ‐3)In: International Journal of Cancer Jg. 150 (2022) Nr. 8, S. 1341 - 1349Online Volltext: dx.doi.org/ (Open Access)
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⁶⁸Ga]FAPI-PET/CT for radiation therapy planning in biliary tract, pancreatic ductal adeno-, and adenoidcystic carcinomasIn: Scientific Reports Jg. 12 (2022) Nr. 1, 16261Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Adding cetuximab to paclitaxel and carboplatin for first-line treatment of carcinoma of unknown primary (CUP) : Results of the Phase 2 AIO trial PACET-CUPIn: British Journal of Cancer (BJC) Jg. 124 (2021) Nr. 4, S. 721 - 727Online Volltext: dx.doi.org/ (Open Access)
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Antitumor immune response is associated with favorable survival in GEP-NEN G3In: Endocrine-Related Cancer Jg. 28 (2021) Nr. 10, S. 683 - 693Online Volltext: dx.doi.org/
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Changes in fatigue, barriers, and predictors towards physical activity in advanced cancer patients over a period of 12 months : A comparative studyIn: Supportive Care in Cancer Jg. 29 (2021) Nr. 9, S. 5127 - 5137Online Volltext: dx.doi.org/ (Open Access)
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Combined systemic inflammation score (SIS) correlates with prognosis in patients with advanced pancreatic cancer receiving palliative chemotherapyIn: Journal of Cancer Research and Clinical Oncology Jg. 147 (2021) Nr. 2, S. 579 - 591Online Volltext: dx.doi.org/ (Open Access)
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Dose-escalated radiotherapy with PET/CT based treatment planning in combination with induction and concurrent chemotherapy in locally advanced (uT3/T4) squamous cell cancer of the esophagus : mature results of a phase I/II trialIn: Radiation Oncology Jg. 16 (2021) Nr. 1, S. 59Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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GPR15 facilitates recruitment of regulatory T cells to promote colorectal cancerIn: Cancer Research Jg. 81 (2021) Nr. 11, S. 2970 - 2982Online Volltext: dx.doi.org/; Online Volltext: dx.doi.org/ (Open Access)
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Identification of a Prognostic Clinical Score for Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck Treated With Systemic Therapy Including CetuximabIn: Frontiers in Oncology Jg. 11 (2021) 635096Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Noninferiority of cetuximab every-2-weeks versus standard once-weekly administration schedule for the first-line treatment of RAS wild-type metastatic colorectal cancerIn: European Journal of Cancer (EJC) Jg. 144 (2021) S. 291 - 301Online Volltext: dx.doi.org/ (Open Access)
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A phase 1b study of the MET inhibitor capmatinib combined with cetuximab in patients with MET-positive colorectal cancer who had progressed following anti-EGFR monoclonal antibody treatmentIn: Investigational New Drugs: The Journal of New Anticancer Agents Jg. 38 (2020) S. 1774 - 1783Online Volltext: dx.doi.org/
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Adjuvant MUC vaccination with tecemotide after resection of colorectal liver metastases : A randomized, double-blind, placebo-controlled, multicenter AIO phase II trial (LICC)In: OncoImmunology Jg. 9 (2020) Nr. 1, 1806680Online Volltext: dx.doi.org/ (Open Access)
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Biweekly Cetuximab Plus FOLFOX6 as First-Line Therapy in Patients With RAS Wild-Type Metastatic Colorectal Cancer : The CEBIFOX TrialIn: Clinical Colorectal Cancer Jg. 19 (2020) Nr. 4, S. 236 - 247.e6Online Volltext: dx.doi.org/
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Effcacy and safety of CAP7.1 as second-line treatment for advanced biliary tract cancers : Data from a randomised phase II studyIn: Cancers Jg. 12 (2020) Nr. 11, S. 1 - 16Online Volltext: dx.doi.org/ (Open Access)
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Fatigue, barriers to physical activity and predictors for motivation to exercise in advanced Cancer patientsIn: BMC Palliative Care Jg. 19 (2020) Nr. 1, S. 43Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Mapping Patient Data to Colorectal Cancer Clinical Algorithms for Personalized Guideline-Based TreatmentIn: Applied Clinical Informatics Jg. 11 (2020) Nr. 2, S. 200 - 209Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Photochemical internalization and gemcitabine combined with first-line chemotherapy in perihilar cholangiocarcinoma: observations in three patientsIn: Endoscopy International Open Jg. 08 (2020) Nr. 12, S. E1878 - E1883Online Volltext: dx.doi.org/ (Open Access)
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Stellenwert und qualitative Voraussetzungen der Magnetresonanztomografie für die Therapieplanung beim lokal fortgeschrittenen Rektumkarzinom - Interdisziplinäre EmpfehlungenIn: Zeitschrift für Gastroenterologie Jg. 58 (2020) Nr. 6, S. 577 - 582Online Volltext: dx.doi.org/
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Stellenwert und qualitative Voraussetzungen der Magnetresonanztomographie für die Therapieplanung beim lokal fortgeschrittenen Rektumkarzinom – interdisziplinäre EmpfehlungenIn: Best Practice Onkologie Jg. 15 (2020) Nr. 7-8, S. 300 - 306Online Volltext: dx.doi.org/
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Was erwartet der Nichtradiologe vom Radiologen?In: Der Radiologe Jg. 60 (2020) Nr. 5, S. 421 - 429Online Volltext: dx.doi.org/
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Immunonkologie von Kopf-Hals-TumorenIn: HNO Jg. 67 (2019) Nr. 3, S. 221 - 235Online Volltext: dx.doi.org/
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Impact of RAS mutation subtype on clinical outcome : A cross-entity comparison of patients with advanced non-small cell lung cancer and colorectal cancerIn: Oncogene Jg. 38 (2019) Nr. 16, S. 2953 - 2966Online Volltext: dx.doi.org/
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Long-term Survival after resection for perihilar cholangiocarcinoma : Impact of UICC staging and surgical procedureIn: The Turkish Journal of Gastroenterology Jg. 30 (2019) Nr. 5, S. 454 - 460Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Long-term outcome of patients with advanced pancreatic cancer treated with sequential chemotherapies before the era of modern combination therapy protocolsIn: Journal of Cancer Research and Clinical Oncology Jg. 145 (2019) Nr. 2, S. 445 - 455Online Volltext: dx.doi.org/
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Natural Language Processing of German Clinical Colorectal Cancer Notes for Guideline-Based Treatment EvaluationIn: International Journal of Medical Informatics Jg. 127 (2019) S. 141 - 146Online Volltext: dx.doi.org/ (Open Access)
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Nivolumab treatment beyond RECIST‐defined progression in recurrent or metastatic squamous cell carcinoma of the head and neck in CheckMate 141 : A subgroup analysis of a randomized phase 3 clinical trialIn: Cancer Jg. 125 (2019) Nr. 18, S. 3208 - 3218Online Volltext: dx.doi.org/ (Open Access)
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Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4) : A randomised, phase 2/3 trialIn: Lancet Jg. 393 (2019) Nr. 10184, S. 1948 - 1957Online Volltext: dx.doi.org/
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Randomized phase II trial of the carboxylesterase (CES)-converted novel drug EDO-S7.1 in patients (pts) with advanced biliary tract cancers (BTC)In: Journal of Clinical Oncology (JCO) Jg. 37 (2019) Nr. 4_Suppl, S. 264 - 264Online Volltext: dx.doi.org/
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The IL-33/ST2 pathway shapes the regulatory T cell phenotype to promote intestinal cancerIn: Mucosal Immunology Jg. 12 (2019) Nr. 4, S. 990 - 1003Online Volltext: dx.doi.org/ (Open Access)
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A novel biomarker combination and its association with resistance to chemotherapy combinations with bevacizumab : First results of the PERMAD trialIn: Annals of Oncology Jg. 29 (2018) Nr. Suppl. 8, S. viii159Online Volltext: dx.doi.org/ (Open Access)
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CA19-9 beim intrahepatischen Cholangiokarzinom : Ein diagnostisches und prognostisches Armamentarium?In: Der Chirurg Jg. 89 (2018) Nr. 6, S. 466 - 471Online Volltext: dx.doi.org/
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CheckMate 141 : 1-Year Update and Subgroup Analysis of Nivolumab as First-Line Therapy in Patients with Recurrent/Metastatic Head and Neck CancerIn: The Oncologist Jg. 23 (2018) Nr. 9, S. 1079 - 1082Online Volltext: dx.doi.org/ (Open Access)
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Comparison of the sixth and the seventh editions of the UICC classification for intrahepatic cholangiocarcinomaIn: European Journal of Medical Research Jg. 23 (2018) Nr. 1, S. 29Online Volltext: dx.doi.org/ (Open Access)
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Immunonkologie von Kopf-Hals-TumorenIn: Best Practice Onkologie Jg. 13 (2018) Nr. 6, S. 336 - 349Online Volltext: dx.doi.org/
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MET Expression in Advanced Non–Small-Cell Lung Cancer : Effect on Clinical Outcomes of Chemotherapy, Targeted Therapy, and ImmunotherapyIn: Clinical Lung Cancer Jg. 19 (2018) Nr. 4, S. e441 - e463Online Volltext: dx.doi.org/
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Nivolumab vs investigator's choice in recurrent or metastatic squamous cell carcinoma of the head and neck : 2-year long-term survival update of CheckMate 141 with analyses by tumor PD-L1 expressionIn: Oral Oncology Jg. 81 (2018) S. 45 - 51Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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PICCA study : panitumumab in combination with cisplatin/gemcitabine chemotherapy in KRAS wild-type patients with biliary cancer—a randomised biomarker-driven clinical phase II AIO studyIn: European Journal of Cancer (EJC) Jg. 92 (2018) S. 11 - 19Online Volltext: dx.doi.org/
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Phosphorylation of p70 Ribosomal Protein S6 Kinase β-1 is an Independent Prognostic Parameter in Metastatic Colorectal CancerIn: Clinical Colorectal Cancer Jg. 17 (2018) Nr. 2, S. e331 - e352Online Volltext: dx.doi.org/
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PhotoChemical internalization of gemcitabine followed by gemcitabine/cisplatin in perihilar cholangiocarcinoma : Results from a phase I dose escalation trialIn: Annals of Oncology Jg. 29 (2018) Nr. Suppl. 8, S. viii259 - viii260Online Volltext: dx.doi.org/ (Open Access)
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Safety profile of trifluridine/tipiracil monotherapy in clinical practice : results of the German compassionate-use program for patients with metastatic colorectal cancerIn: BMC Cancer Jg. 18 (2018) S. 1124Online Volltext: dx.doi.org/ (Open Access)
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Buparlisib and paclitaxel in patients with platinum-pretreated recurrent or metastatic squamous cell carcinoma of the head and neck (BERIL-1) : a randomised, double-blind, placebo-controlled phase 2 trialIn: The Lancet Oncology Jg. 18 (2017) Nr. 3, S. 323 - 335Online Volltext: dx.doi.org/
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Characterisation of Potential Predictive Biomarkers of Response to Nivolumab in Checkmate 141 in Patients With Squamous Cell Carcinoma of the Head and Neck (SCCHN)In: Asia-Pacific Journal of Clinical Oncology Jg. 13 4 (2017) S. 141 - 141
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Comprehensive biomarker analyses in patients with advanced or metastatic non-small cell lung cancer prospectively treated with the polo-like Kinase 1 Inhibitor BI2536In: Oncology Research and Treatment Jg. 40 (2017) Nr. 7-8, S. 435 - 439Online Volltext: dx.doi.org/
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Docetaxel, oxaliplatin, and fluorouracil/leucovorin (FLOT) for resectable esophagogastric cancer : Updated results from multicenter, randomized phase 3 FLOT4-AIO trial (German Gastric Group at AIO)In: Annals of Oncology Jg. 28 (2017) Nr. Suppl. 5,
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High Prevalence of Concomitant Oncogene Mutations in Prospectively Identified Patients with ROS1-Positive Metastatic Lung CancerIn: Journal of Thoracic Oncology Jg. 12 (2017) Nr. 1, S. 54 - 64Online Volltext: dx.doi.org/ (Open Access)
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Molecular dissection of effector mechanisms of RAS-mediated resistance to anti-EGFR antibody therapyIn: OncoTarget Jg. 8 (2017) Nr. 28, S. 45898 - 45917Online Volltext: dx.doi.org/ (Open Access)
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Nivolumab versus standard, single-agent therapy of investigator's choice in recurrent or metastatic squamous cell carcinoma of the head and neck (CheckMate 141) : health-related quality-of-life results from a randomised, phase 3 trialIn: The Lancet Oncology Jg. 18 (2017) Nr. 8, S. 1104 - 1115Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Perioperative chemotherapy with docetaxel, oxaliplatin and fluorouracil/leucovorin (FLOT) versus epirubicin, cisplatin and fluorouracil or capecitabine (ECF/ECX) for resectable gastric or gastroesophageal junction (GEJ) adenocarcinoma (FLOT4-AIO) : a randoIn: Oncology Research and Treatment Jg. 40 (2017) Nr. Suppl. 3: Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, Stuttgart, 29. September-3. Oktober 2017: Abstracts, S. 200 - 201Online Volltext: dx.doi.org/
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Phase I clinical study with photochemical internalisation, a novel technology for treatment of perihilar cholangiocarcinomaIn: Journal of Hepatology Jg. 66 (2017) Nr. 1, S. S452Online Volltext: dx.doi.org/
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Spatiotemporally restricted arenavirus replication induces immune surveillance and type i interferon-dependent tumour regressionIn: Nature Communications Jg. 8 (2017) S. 14447Online Volltext: dx.doi.org/ (Open Access)
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Treatment beyond progression with nivolumab (nivo) in patients with recurrent or metastatic (R/M) Squamous Cell Carcinoma of the Head and Neck (SCCHN) in the phase 3 CheckMate 141 studyIn: Oncology Research and Treatment Jg. 40 (2017) Nr. Suppl. 3, S. 250 - 251
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Cholangiozelluläres Karzinom : Interventionelle und systemische TherapieoptionenIn: Der Gastroenterologe Jg. 11 (2016) Nr. 5, S. 400 - 409Online Volltext: dx.doi.org/
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Circulating U2 small nuclear RNA fragments as a diagnostic and prognostic biomarker in lung cancer patientsIn: Journal of Cancer Research and Clinical Oncology Jg. 142 (2016) Nr. 4, S. 795 - 805Online Volltext: dx.doi.org/
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Differences in gene-expression in mCRC tissue samples with regard to tumor location and used chemotherapeutic substances : Data of the FIRE-1 studyIn: Journal of Clinical Oncology (JCO) Jg. 34 (2016) Nr. Suppl. 4, S. 562Online Volltext: dx.doi.org/
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Klatskin-Tumor : Langzeitüberleben nach OperationIn: Der Chirurg Jg. 87 (2016) Nr. 6, S. 514 - 519Online Volltext: dx.doi.org/
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Cetuximab biweekly plus mFOLFOX6 as first-line therapy in patients (pts) with KRAS wild-type (wt) (exon 2) metastatic colorectal cancer (mCRC) : Primary endpoint and subgroup analysis of the CEBIFOX trialIn: Journal of Clinical Oncology (JCO) Jg. 33 (2015) Nr. 15 Suppl., S. 3568Online Volltext: dx.doi.org/
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HER2 expression and markers of phosphoinositide-3-kinase pathway activation define a favorable subgroup of metastatic pulmonary adenocarcinomasIn: Lung Cancer Jg. 88 (2015) Nr. 1, S. 34 - 41Online Volltext: dx.doi.org/
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Molecular dissection of the impact of frequent genetic alterations on the response of head and neck cancers to anti-epidermal growth factor receptor-directed therapiesIn: Oral Oncology Jg. 51 (2015) Nr. 5, S. e39Online Volltext: dx.doi.org/
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Development of a Highly Sensitive and Specific Method for Detection of Circulating Tumor Cells Harboring Somatic Mutations in Non-Small-Cell Lung Cancer PatientsIn: PLoS ONE Jg. 9 (2014) Nr. 1, e85350Online Volltext: dx.doi.org/ (Open Access)
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Functional expression cloning identifies COX-2 as a suppressor of antigen-specific cancer immunityIn: Cell Death and Disease Jg. 5 (2014) Nr. 12, 1568Online Volltext: dx.doi.org/ (Open Access)
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Impact of human papilloma virus infection on the response of head and neck cancers to anti-epidermal growth factor receptor antibody therapyIn: Cell Death and Disease Jg. 5 (2014) Nr. 2, e1091Online Volltext: dx.doi.org/ (Open Access)
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Transient ablation of regulatory T cells improves antitumor immunity in colitis-associated colon cancerIn: Cancer Research Jg. 74 (2014) Nr. 16, S. 4258 - 4269Online Volltext: dx.doi.org/
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Cetuximab biweekly plus mFOLFOX6 as first-line therapy in patients (pts) with KRAS wild-type (wt) metastatic colorectal cancer (mCRC) : An interim analysis of the CEBIFOX trialIn: Journal of Clinical Oncology (JCO) Jg. 31 (2013) Nr. 15 Suppl., S. e14502Online Volltext: dx.doi.org/
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Feasibility of preemptive biomarker profiling for personalised early clinical drug development at a Comprehensive Cancer CenterIn: European Journal of Cancer (EJC) Jg. 49 (2013) Nr. 15, S. 3076 - 3082Online Volltext: dx.doi.org/
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Oncogenic RAS simultaneously protects against anti-EGFR antibody-dependent cellular cytotoxicity and EGFR signaling blockadeIn: Oncogene Jg. 32 (2013) Nr. 23, S. 2873 - 2881Online Volltext: dx.doi.org/
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Preemptive tumor profiling for biomarker-stratified early clinical drug development in metastatic breast cancer patientsIn: Breast Cancer Research and Treatment Jg. 142 (2013) Nr. 1, S. 81 - 88Online Volltext: dx.doi.org/
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Stabilization of Physical RAF/14-3-3 Interaction by Cotylenin A as Treatment Strategy for RAS Mutant CancersIn: ACS Chemical Biology Jg. 8 (2013) Nr. 9, S. 1869 - 1875Online Volltext: dx.doi.org/
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Antikörper zur adoptiven Immuntherapie solider TumorenIn: Der Onkologe Jg. 18 (2012) Nr. 9, S. 757 - 769Online Volltext: dx.doi.org/
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LICC: L-BLP25 in patients with colorectal carcinoma after curative resection of hepatic metastases-a randomized, placebo-controlled, multicenter, multinational, double-blinded phase II trialIn: BMC Cancer Jg. 12 (2012) S. 144Online Volltext: dx.doi.org/ (Open Access)
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Pharmacologic inhibition of mTOR antagonizes the cytotoxic activity of pemetrexed in non-small cell lung cancerIn: Journal of Cancer Research and Clinical Oncology Jg. 138 (2012) Nr. 4, S. 545 - 554Online Volltext: dx.doi.org/
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Targeting MCL-1 sensitizes FLT3-ITD-positive leukemias to cytotoxic therapiesIn: Blood Cancer Journal Jg. 2 (2012) Nr. 3, S. e60Online Volltext: dx.doi.org/ (Open Access)
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Targeting the anti-apoptotic protein BCL-XL to overcome RAS mediated resistance to anti-EGFR antibody therapy in colorectal cancerIn: Onkologie Jg. 35 (2012) Nr. Suppl. 6, S. 253
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VVTZ-Tumorprofil - First results of a preemptive biomarker profiling program in relation to personalized clinical drug development at a large German Comprehensive Cancer CenterIn: Onkologie Jg. 35 (2012) Nr. Suppl. 6, S. 204 - 204
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Βv-tubulin expression is associated with outcome following taxane-based chemotherapy in non-small cell lung cancerIn: British Journal of Cancer (BJC) Jg. 107 (2012) Nr. 5, S. 823 - 830Online Volltext: dx.doi.org/ (Open Access)
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Comparison of PIK3CA Hot Spot Mutations in the Primary Tumor or Metastases with PIK3CA Mutations or PIK3CA Over-Expression in Circulating Tumor Cells of Metastatic Breast Cancer Patients under Sequential Palliative TherapyIn: Cancer Research Jg. 71 (2011) Nr. Suppl. 24,Online Volltext: dx.doi.org/
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Evaluation of Betav-Tubulin expression as novel predictive biomarker for clinical benefit from treatment with taxanes in non-small cell lung cancerIn: Journal of Thoracic Oncology Jg. 6 (2011) Nr. Suppl. 6, S. 1078
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Pharmacological Inhibition of NF-k and PLK-1 to the Opening of the RAS-mediated Resistance to anti-EGFR Antibody therapies in Colorectal cancer *In: Der Internist Jg. 52 (2011) Nr. 6, S. 726 - 726
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Simultaneous protection against anti-EGFR antibody-dependent cellular cytotoxicity and EGFR-signaling blockade by oncogenic RASIn: Journal of Clinical Oncology (JCO) Jg. 29 (2011) Nr. Suppl. 4, S. 440Online Volltext: dx.doi.org/
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Tumor immunology : The new fourth pillar of tumor treatmentIn: Der Onkologe Jg. 27 (2021) Nr. 11, S. 1046 - 1048Online Volltext: dx.doi.org/ (Open Access)
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Dermatology-related quality of life outcomes in patients with RAS wild-type (wt) metastatic colorectal cancer (mCRC) treated with fluorouracil and folinic acid with or without panitumumab (Pmab) maintenance after FOLFOX + Pmab induction : A prespecified secondary analysis of the phase 2 randomized PanaMa (AIO KRK 0212) trialIn: Journal of Clinical Oncology (JCO) Jg. 42 (2024) Nr. Suppl. 16, e15539Online Volltext: dx.doi.org/ (Open Access)
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FU/FA maintenance therapy with or without panitumumab (pmab) in RAS wild-type metastatic colorectal cancer (mCRC) (PanaMa, AIO KRK 0212) : Updated efficacy analysesIn: Journal of Clinical Oncology (JCO) Jg. 42 (2024) Nr. Suppl. 16, 3506Online Volltext: dx.doi.org/ (Open Access)
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Prediction of resistance to bevacizumab plus FOLFOX in metastatic colorectal cancer using a multi-marker panel and a machine-learning approach : Final results of the prospective multicenter PERMAD trialIn: Journal of Clinical Oncology (JCO) Jg. 42 (2024) Nr. Suppl. 3, S. 204 - 204Online Volltext: dx.doi.org/
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Quality-adjusted time without symptoms of disease or toxicity (Q-TWiST) analysis of fruquintinib + best supportive care (BSC) compared with placebo + BSC in metastatic colorectal cancer (mCRC) : Results from the FRESCO-2 trialIn: Journal of Clinical Oncology (JCO) Jg. 42 (2024) Nr. Suppl. 3, 116Online Volltext: dx.doi.org/
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HER2-low as potential prognostic biomarker in patients (pts) with metastatic or recurrent Gastric Cancer (GC) or esophageal-gastric junction (AEG) adenocarcinoma
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 13. bis 16. Oktober 2023, Hamburg, Germany,In: Oncology Research and Treatment Jg. 46 (2023) Nr. Supplement 5: DGHO Abstracts, S. 117 - 118Online Volltext: dx.doi.org/ (Open Access) -
Consensus molecular subtypes (CMS) as prognostic and predictive biomarkers of panitumumab (Pmab), fluorouracil and folinic acid (FU/FA) or FU/FA maintenance therapy following Pmab-FOLFOX induction in RAS wildtype metastatic colorectal cancer (mCRC) : PANAMA trial (AIO-KRK-0212)In: Journal of Clinical Oncology (JCO) Jg. 40 (2022) Nr. 16_Suppl., S. 3537Online Volltext: dx.doi.org/
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Negative hyperselection for mutations associated with anti-EGFR antibody resistance in RAS wildtype metastatic colorectal cancer (mCRC) : Evaluation of the PANAMA trial (AIO-KRK-0212, maintenance therapy with 5-FU, folinic acid (FU/FA) with or without panitumumab)In: Journal of Clinical Oncology (JCO) Jg. 40 (2022) Nr. 16_Suppl., S. 3536Online Volltext: dx.doi.org/
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P-23 Phase II study (daNIS-3) of the anti–TGF-β monoclonal antibody NIS793 and other new investigational drug combinations with standard-of-care therapy vs standard-of-care alone in patients with second-line metastatic colorectal cancerIn: Annals of Oncology Jg. 33 (2022) S. 254 - S255Online Volltext: dx.doi.org/ (Open Access)
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PSMA-directed imaging and therapy of salivary gland tumors : a single-center retrospective study
EANM‘22 ; 35th Annual Congress of the European Association of Nuclear Medicine ; October 15-19, 2022, Barcelona, Spain,In: European Journal of Nuclear Medicine and Molecular Imaging Jg. 49 (2022) Nr. Supplement 1, S. S229Online Volltext: dx.doi.org/ (Open Access) -
Predictive and prognostic value of carcinoembryonic antigen (CEA) on maintenance therapy with 5-fluoruracil/leucovorin plus panitumumab or 5-fluoruracil/leucovorin alone in RAS wildtype metastatic colorectal cancer : Evaluation of the phase II PanaMa trial (AIO KRK 0212)In: Journal of Clinical Oncology (JCO) Jg. 40 (2022) Nr. 16_Suppl., S. 3587Online Volltext: dx.doi.org/ (Open Access)
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Randomized study to investigate a switch maintenance concept with 5-FU plus bevacizumab after FOLFIRI plus cetuximab induction treatment versus continued treatment with FOLFIRI plus cetuximab : Report of a secondary endpoint of the phase-III FIRE-4 study (AIO KRK-0114)In: Journal of Clinical Oncology (JCO) Jg. 40 (2022) Nr. 16_Suppl., S. 3519Online Volltext: dx.doi.org/ (Open Access)
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SO-16 FIRE-4 (AIO-KRK-0114) : Randomized study for a switch maintenance concept with 5-FU plus bevacizumab after induction treatment with FOLFIRI plus cetuximab versus continued treatment with FOLFIRI plus cetuximab – secondary endpoint
ESMO 24th World Congress on Gastrointestinal Cancer 2022, 29 June -2 July 2022, Barcelona, Spain,In: Annals of Oncology Jg. 33 (2022) Nr. Suppl. 4, S. S363 - S364Online Volltext: dx.doi.org/ (Open Access) -
Superiority of [68Ga]Ga-FAPI-46 over [18F]F-FDG PET/CT for cholangiocarcinoma imaging
EANM‘22 ; 35th Annual Congress of the European Association of Nuclear Medicine ; October 15-19, 2022 Barcelona, Spain,In: European Journal of Nuclear Medicine and Molecular Imaging Jg. 49 (2022) Nr. Supplement 1, S. S192 - S193Online Volltext: dx.doi.org/ (Open Access) -
Target Expression and FAP-Directed Tumour Imaging in a Large, Single-Centre PET Database of 324 Patients and 21 Tumour Entities
EANM‘22 ; 35th Annual Congress of the European Association of Nuclear Medicine ; October 15-19, 2022, Barcelona, Spain,In: European Journal of Nuclear Medicine and Molecular Imaging Jg. 49 (2022) Nr. Supplement 1, S. S119 - S120Online Volltext: dx.doi.org/ (Open Access) -
ELDORANDO : Pembrolizumab compared with methotrexate in elderly, frail or cisplatin-ineligible patients with relapsed or metastatic squamous cell carcinoma of the head and neck (RM-SCCHN) (ELDORANDO-AIO-KHT-0115)
Gemeinsame Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 01.-04. Oktober 2021, Hybrid-Kongress,In: Oncology Research and Treatment Jg. 44 (2021) Nr. Supplement 2, S. 56 - 57Online Volltext: dx.doi.org/ (Open Access) -
Efficacy of immunotherapy (IO) and subsequent systemic treatment after failure of IO in patients with recurrent or metastatic head and neck cancer in a real-world settingIn: Annals of Oncology Jg. 32 (2021) Nr. Suppl. 5, S. 812Online Volltext: dx.doi.org/ (Open Access)
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Maintenance therapy with 5-fluoruracil/leucovorin (5FU/LV) plus panitumumab (pmab) or 5FU/LV alone in RAS wildtype (WT) metastatic colorectal cancer (mCRC) - the PANAMA trial (AIO KRK 0212)In: Journal of Clinical Oncology (JCO) Jg. 39 (2021) Nr. 15_Suppl, S. 3503 - 3503Online Volltext: dx.doi.org/
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Phase (Ph) II study of taminadenant (NIR178) + spartalizumab (PDR001) in patients (pts) with microsatellite stable (MSS) colorectal cancer (CRC)In: Annals of Oncology Jg. 32 (2021) Nr. Suppl. 5, S. 552 - S553Online Volltext: dx.doi.org/ (Open Access)
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Predicting resistance to first-line FOLFOX plus bevacizumab in metastatic colorectal cancer : Final results of the multicenter, international PERMAD trial
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Prognostic Significance of the metabolic Response during Induction Chemotherapy for the definitive Chemoradiotherapy of locally advanced Squamous Cell Carcinoma of the EsophagusIn: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 197 (2021) Nr. Suppl. 1, S. 154 - S155
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RAMucirumab in combination with TAS102 versus TAS102 monotherapy in metastatic colorectal cancer : Safety results from the phase IIb part of the RAMTAS phase II/III trial of the German AIO (AIO-KRK-0316)In: Journal of Clinical Oncology (JCO) Jg. 39 (2021) Nr. 15_Suppl, S. 3566 - 3566Online Volltext: dx.doi.org/
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Randomized study to investigate FOLFOXIRI plus either bevacizumab or cetuximab as first-line treatment of BRAF V600E-mutant mCRC : The phase-II FIRE-4.5 study (AIO KRK-0116)In: Journal of Clinical Oncology (JCO) Jg. 39 (2021) Nr. 15_Suppl, S. 3502 - 3502Online Volltext: dx.doi.org/
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Results of a randomized phase II study comparing pembrolizumab with methotrexate in elderly, frail or cisplatin-ineligible patients with relapsed or metastatic squamous cell carcinoma of the head and neck (RM-SCCHN) (ELDORANDO-AIO-KHT-0115)In: Annals of Oncology Jg. 32 (2021) Nr. Suppl. 5, S. 807 - S808Online Volltext: dx.doi.org/ (Open Access)
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Interim safety analysis of the phase IIb study of ramucirumab in combination with TAS102 vs. TAS102 monotherapy in metastatic colorectal cancer : The RAMTAS trial of the German AIOIn: Annals of Oncology Jg. 31 (2020) Nr. Suppl. 4, S. S427 - S428Online Volltext: dx.doi.org/ (Open Access)
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Patients with metastatic EGFR-mutated non-small cell lung cancer (NSCLC) show highly favorable outcomes with treatment sequences provided at a comprehensive cancer center
Virtuelle Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 09.–11. Oktober 2020,In: Oncology Research and Treatment Jg. 43 (2020) Nr. Suppl. 4, S. 137Online Volltext: dx.doi.org/ (Open Access) -
A phase IIb study of ramucirumab in combination with TAS102 versus TAS102 monotherapy in metastatic, chemotherapy refractory colorectal cancer patients : The RAMTAS trial of the German AIO (KRK-0316)In: Journal of Clinical Oncology (JCO) Jg. 37 (2019) Nr. 15, S. TPS3617 - TPS3617Online Volltext: dx.doi.org/
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PET-directed combined modality therapy for gastroesophageal junction cancer : First results of the prospective MEMORI trialIn: Journal of Clinical Oncology (JCO) Jg. 37 (2019) Nr. 15, S. 4018 - 4018Online Volltext: dx.doi.org/
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Paclitaxel/carboplatin with or without cetuximab for treatment of carcinoma with unknown primary (PACET-CUP) : Results of a multi-center randomized phase II AIO trialIn: Journal of Clinical Oncology (JCO) Jg. 37 (2019) Nr. 15, S. 4120Online Volltext: dx.doi.org/ (Open Access)
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Phase Ib study of MIW815 (ADU-S100) in combination with spartalizumab (PDR001) in patients (pts) with advanced/metastatic solid tumors or lymphomasIn: Journal of Clinical Oncology (JCO) Jg. 37 (2019) Nr. 15, S. 2507 - 2507Online Volltext: dx.doi.org/ (Open Access)
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A novel biomarker combination and its association with resistance to chemotherapy combinations with bevacizumab : First results of the PERMAD trialIn: Journal of Clinical Oncology (JCO) Jg. 36 (2018) Nr. Suppl. 15, S. e15545 - e15545Online Volltext: dx.doi.org/ (Open Access)
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Efficacy and safety of Trifluridin/Tipiracil (FTD/TPI) (Lonsurf (R)) in patients with metastatic colorectal cancer (CRC) in clinical-routine use
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 4, S. 289Online Volltext: dx.doi.org/ (Open Access) -
Evaluation of prognostic markers in patients (pts) with advanced gastric cancer (GC) and adenocarcinoma of the gastroesophageal junction (AEG) treated with systemic chemothearpy (ctx) at the West German Cancer Center
33. Deutscher Krebskongress - Perspektiven verändern Krebs - Krebs verändert Perspektiven. Diagnose - Therapie - (Über-)Leben ; 21.-24. Februar 2018, Berlin,In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 1, S. 67Online Volltext: dx.doi.org/ (Open Access) -
Nivolumab (Nivo) vs Investigator‘s Choice (IC) for Platinum-Refractory (PR) Recrrent or Metastatic (R/M) Squamous Cell Carcinoma of the Head and Neck (SCCHN; CheckMate 141) : Outcomes in First-line (1L) R/M Patients (Pts) and Updated Safety and Efficacy
33. Deutscher Krebskongress - Perspektiven verändern Krebs - Krebs verändert Perspektiven. Diagnose - Therapie - (Über-)Leben ; 21.-24. Februar 2018, Berlin,In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 1, S. 96Online Volltext: dx.doi.org/ (Open Access) -
Nivolumab (Nivo) vs investigator's choice (IC) in recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN) : 2-yr outcomes in the overall population and PD-L1 subgroups of CheckMate 141In: Cancer Research Jg. 78 (2018) Nr. Suppl. 13,Online Volltext: dx.doi.org/
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PD-L1 mRNA expression in patients with resectable gastric cancer and adenocarcinoma of the oesophago-gastric junction undergoing perioperative chemotherapy : Results from the FLOT4 phase III trial of the AIOIn: Journal of Clinical Oncology (JCO) Jg. 36 (2018) Nr. Suppl. 15, S. e24277 - e24277Online Volltext: dx.doi.org/ (Open Access)
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Signaling network activation in colorectal cancer : p70S6K phosphorylation as a prognostic marker
33. Deutscher Krebskongress - Perspektiven verändern Krebs - Krebs verändert Perspektiven. Diagnose - Therapie - (Über-)Leben ; 21.-24. Februar 2018, Berlin,In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 1, S. 55Online Volltext: dx.doi.org/ (Open Access) -
The prognostic impact of UDP-glucuronyltransferase 1A1*1 (UGT1A1*1) polymorphism in patients with advanced colorectal and non-colorectal cancer treated with irinotecan-based systemic chemotherapies
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie ; 28. September - 2. Oktober 2018, Wien,In: Oncology Research and Treatment Jg. 41 (2018) Nr. Suppl. 4, S. 122 - 123Online Volltext: dx.doi.org/ (Open Access) -
Two-year Update From CheckMate 141 : Outcomes With Nivolumab (Nivo) vs Investigator's Choice (IC) in Recurrent or Metastatic (R/M) Squamous Cell Carcinoma of the Head and Neck (SCCHN) in the Overall Population and PD-L1 Subgroups
2018 Multidisciplinary Head and Neck Cancers Symposium ; Expanding Treatment Horizons ; February 15-17, 2018, Scottsdale, Arizona, USA,In: International Journal of Radiation Oncology, Biology, Physics Jg. 100 (2018) Nr. 5, S. 1317 - 1317Online Volltext: dx.doi.org/ (Open Access) -
Nivolumab vs investigator's choice (IC) in patients with recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN) : treatment effect on clinical outcomes by best overall response in checkmate 141
42nd ESMO Congress (ESMO 2017) ; 8-12 September 2017, Madrid, Spain,In: Annals of Oncology Jg. 28 (2017) Nr. Suppl. 5, S. v377 - v378Online Volltext: dx.doi.org/ -
Treatment beyond progression with nivolumab in patients with recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN) in the phase 3 checkmate 141 study : A biomarker analysis and updated clinical outcomes
42nd ESMO Congress (ESMO 2017) ; 8-12 September 2017, Madrid, Spain,In: Annals of Oncology Jg. 28 (2017) Nr. Suppl. 5, S. v372 - v373Online Volltext: dx.doi.org/ -
Evaluation of prognostic markers in patients (pts) with metastatic colorectal cancer (mCRC) treated with a bevacizumab (bev) based chemotherapy (ctx) at the West German Cancer Center
Krebsmedizin heute: präventiv, personalisiert, präzise und partizipativ ; 32. Deutscher Krebskongress ; 24.-27. Februar 2016, Berlin,In: Oncology Research and Treatment Jg. 39 (2016) Nr. Suppl. 1, S. 77Online Volltext: dx.doi.org/ -
Evaluation of systemic inflammatory response (SIR) markers in recurrent or metastatic head and neck squamous cell carcinoma (r/m HNSCC)In: Oncology Research and Treatment Jg. 39 (2016) Nr. Suppl. 3, S. 307 - 308Online Volltext: dx.doi.org/
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Evaluation of systemic inflammatory response (SIR) markers in advanced biliary tract cancer (ABTC)
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 9.-13. Oktober 2015, Basel, Schweiz,In: Oncology Research and Treatment Jg. 38 (2015) Nr. Suppl. 5, S. 5 - 6Online Volltext: dx.doi.org/ -
Evaluation of systemic inflammatory response (SIR) markers in pancreatic ductal adenocarcinoma (PDAC)In: Oncology Research and Treatment Jg. 38 (2015) Nr. S 5, Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 9.-13. Oktober 2015, Basel, Schweiz, S. 4 - 5Online Volltext: dx.doi.org/
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Prognostische Faktoren bei Patienten mit fortgeschrittenen Pankreaskarzinomen, die am Westdeutschen Tumorzentrum (WTZ) sequentielle Chemotherapien erhalten haben
121. Kongress der Deutschen Gesellschaft für Innere Medizin ; DGIM 2015 ; 18. - 21. April 2015, Mannheim, Germany,In: Der Internist Jg. 56 (2015) Nr. Supplement 1: Abstracts zum 121. Kongress der Deutschen Gesellschaft für Innere Medizin e.V., S. 38 - 39Online Volltext: dx.doi.org/ -
Prognostische Faktoren bei Patienten mit fortgeschrittenen cholangiozellulären Karzinomen, die am Westdeutschen Tumorzentrum (WTZ) sequentielle Chemotherapien erhalten haben
121. Kongress der Deutschen Gesellschaft für Innere Medizin ; DGIM 2015 ; 18. - 21. April 2015, Mannheim, Germany,In: Der Internist Jg. 56 (2015) Nr. Supplement 1: Abstracts zum 121. Kongress der Deutschen Gesellschaft für Innere Medizin e.V., S. 37Online Volltext: dx.doi.org/ -
A randomized, double-blind, placebo-controlled, multicenter, binational, phase II trial of immunotherapy with L-BLP25 (tecemotide) in patients with colorectal carcinoma following R0/R1 hepatic metastasectomyIn: Journal of Clinical Oncology (JCO) Jg. 32 (2014) Nr. 15, suppl., S. TPS3658Online Volltext: dx.doi.org/
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Cetuximab biweekly plus mFOLFOX6 as first-line therapy in patients (pts) with KRAS wild-type (wt) metastatic colorectal cancer (mCRC) - Primary endpoint analysis of the CEBIFOX trial
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 10.-14. Oktober 2014, Hamburg,In: Oncology Research and Treatment Jg. 37 (2014) Nr. Suppl. 5, S. 99 - 100Online Volltext: dx.doi.org/ -
Circulating U2 small nuclear RNA fragments as a diagnostic and prognostic biomarker in lung cancer patients
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 10.-14. Oktober 2014, Hamburg,In: Oncology Research and Treatment Jg. 37 (2014) Nr. Suppl. 5, S. 226 - 227Online Volltext: dx.doi.org/ -
Impact of human papilloma virus infection on the response of head and neck cancers (HNSCC) to anti-epidermal growth factor receptor (EGFR) antibody therapy
31. Deutscher Krebskongress iKON - intelligente Konzepte in der Onkologie, 19.-22. Februar 2014, Berlin,In: Oncology Research and Treatment Jg. 37 (2014) Nr. Suppl. 1, S. 76Online Volltext: dx.doi.org/ -
Molecular and clinical predictors of the efficacy of cetuximab in combination with mFOLFOX6 in 1st line treatment of patients (pts) with metastatic colorectal cancer (mCRC) – subgroup analyses of the CEBIFOX trial
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 10.-14. Oktober 2014, Hamburg,In: Oncology Research and Treatment Jg. 37 (2014) Nr. Suppl. 5, S. 100 - 101Online Volltext: dx.doi.org/ -
Outcome of patients (pts) with advanced pancreaticobiliary cancers treated with sequential chemotherapies at the West German Cancer Center (WTZ)
Deutscher Krebskongress iKON - intelligente Konzepte in der Onkologie, 19.-22. Februar 2014, Berlin,In: Oncology Research and Treatment Jg. 37 (2014) Nr. Suppl. 1, S. 51Online Volltext: dx.doi.org/ -
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WTZ-Tumorprofil-A preemptive biomarker profiling program in relation to personalized clinical drug development at a large German Comprehensive Cancer Center : Two years experience
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Molecular dissection of effector mechanisms of RAS-induced resistance to monoclonal anti-EGFR antibodies
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Preemptive tumor profiling for biomarker-stratified early clinical drug development in metastastic breast cancer patients
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Targeting NF-kappa B and PLK-1 to overcome RAS-mediated resistance to anti-EGFR antibody therapy in colorectal cancer
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Therapeutische Modulation onkogener Signaltransduktion bei malignen Erkrankungen und Mechanismen der ResistenzentwicklungDuisburg, Essen (2014) 1 CD-ROM
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Combined amphiregulin and epiregulin expression as a prognostic and predictive biomarker of panitumumab (Pmab), fluorouracil, and folinic acid (FU/FA) or FU/FA maintenance therapy following Pmab+FOLFOX induction in RAS wildtype metastatic colorectal cancer (mCRC) : PANAMA trial (AIO-KRK-0212)
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Analysis of ecacy and treatment pattern of second-line therapy after failure of immunotherapy-based treatment in recurrent or metastatic head and neck squamous cell carcinoma (r/m SCCHN) using the head and neck clinical research platform (HEAT)
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Highly sensitive detection of somatic epidermal growth factor receptor (EGFR) gene mutations in circulating tumor cells (CTC) from patients with non-small cell lung cancer treated with cisplatin/pemetrexed or afatinib
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