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Biologie / ZMB / AG Bioinformatik

Anschrift
Universitätsstr. 2-5
45141 Essen
Raum
S03 S03 A44

Funktionen

  • Doktorand/in, Bioinformatik and Computational Biophysics

Aktuelle Veranstaltungen

Keine aktuellen Veranstaltungen.

Vergangene Veranstaltungen (max. 10)

Keine vergangenen Veranstaltungen.

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Budeus, Bettina; Álvaro-Benito, Miguel; Crivello, Pietro
    HLA-DM and HLA-DO interplay for the peptide editing of HLA class II in healthy tissues and leukemia
    In: Best Practice & Research Clinical Haematology Jg. 37 (2024) Nr. 2, 101561
  • Sentek, Hanna; Braun, Annika; Budeus, Bettina; Klein, Diana
    Non-small cell lung cancer cells and concomitant cancer therapy induce a resistance-promoting phenotype of tumor-associated mesenchymal stem cells
    In: Frontiers in Oncology Jg. 14 (2024) 1406268
  • Kibler, Artur; Seifert, Marc; Budeus, Bettina
    Age-related changes of the human splenic marginal zone B cell compartment
    In: Immunology Letters Jg. 256-257 (2023) S. 59 - 65
  • Küppers, Ralf; Budeus, Bettina; Hartmann, Sylvia; Hansmann, Martin-Leo
    Clonal composition and differentiation stage of human CD30⁺ B cells in reactive lymph nodes
    In: Frontiers in Immunology Jg. 14 (2023) 1208610
  • Budeus, Bettina; Unger, Kristian; Hess, Julia; Sentek, Hanna; Klein, Diana
    Comparative computational analysis to distinguish mesenchymal stem cells from fibroblasts
    In: Frontiers in Immunology Jg. 14 (2023) 1270493
  • Zec, Kristina; Thiebes, Stephanie; Bottek, Jenny; Siemes, Devon; Spangenberg, Philippa; Trieu, Duc Viet; Kirstein, Nils; Subramaniam, Nirojah; Christ, Robin; Klein, Diana; Jendrossek, Verena; Loose, Maria; Wagenlehner, Florian; Jablonska, Jadwiga; Bracht, Thilo; Sitek, Barbara; Budeus, Bettina; Klein-Hitpaß, Ludger; Theegarten, Dirk; Shevchuk, Olga; Engel, Daniel Robert
    Comparative transcriptomic and proteomic signature of lung alveolar macrophages reveals the integrin CD11b as a regulatory hub during pneumococcal pneumonia infection
    In: Frontiers in Immunology Jg. 14 (2023) 1227191
  • Kronimus, Yannick; Albus, Alexandra; Hasenberg, Mike; Walkenfort, Bernd; Seifert, Marc; Budeus, Bettina; Gronewold, Janine; Hermann, Dirk M.; Ross, J. Alexander; Lochnit, Günter; Galuska, Sebastian P.; Marcus, Katrin; Sitek, Barbara; Klotsche, Jens; Mengel, David; Neumann, Sascha; Dodel, Richard
    Fc N-glycosylation of autoreactive Aβ antibodies as a blood-based biomarker for Alzheimer's disease
    In: Alzheimer's & Dementia Jg. 19 (2023) Nr. 12, S. 5563 - 5572
  • Budeus, Bettina; Kibler, Artur; Küppers, Ralf
    Human IgM–expressing memory B cells
    In: Frontiers in Immunology Jg. 14 (2023) 1308378
  • Dubler, Simon; Etringer, Michael; Weigand, Markus A.; Brenner, Thorsten; Zimmermann, Stefan; Schnitzler, Paul; Budeus, Bettina; Rengier, Fabian; Kalinowska, Paulina; Hoo, Yuan Lih; Lichtenstern, Christoph
    Impact of Invasive Pulmonary Aspergillosis in Critically Ill Surgical Patients with or without Solid Organ Transplantation
    In: Journal of Clinical Medicine (JCM) Jg. 12 (2023) Nr. 9, 3282
  • Röder, Bettina; Fahnenstiel, Hannah; Schäfer, Simon; Budeus, Bettina; Dampmann, Maria; Eichhorn, Melanie; Angermüller, Sieglinde; Brost, Claudia; Winkler, Thomas H; Seifert, Marc; Nitschke, Lars
    The inhibitory receptor Siglec-G controls the severity of chronic lymphocytic leukemia
    In: EMBO Reports Jg. 24 (2023) Nr. 8, e56420
  • Miroschnikov, Natalia; Dräger, Oliver; Van Meenen, Dario; Metz, Klaus; Budeus, Bettina; Dünker, Nicole; Busch, Maike
    Tumor Suppressor Role of INPP4B in Chemoresistant Retinoblastoma
    In: Journal of Oncology (2023) 2270097
  • Antoni, Anne-Charlotte; Pylaeva, Ekaterina; Budeus, Bettina; Jablonska, Jadwiga; Klein-Hitpaß, Ludger; Dudda, Marcel; Flohé, Stefanie B.
    TLR2-induced CD8⁺ T-cell deactivation shapes dendritic cell differentiation in the bone marrow during sepsis
    In: Frontiers in Immunology Jg. 13 (2022) 945409
  • Kibler, Artur; Budeus, Bettina; Küppers, Ralf; Seifert, Marc
    The Splenic Marginal Zone in Children Is Characterized by a Subpopulation of CD27-Negative, Lowly IGHV-Mutated B Cells
    In: Frontiers in Immunology Jg. 13 (2022) 825619
  • Weiß, Annika L.; Meijer, Mandy; Budeus, Bettina; Pauper, Marc; Hakobjan, Marina; Groothuismink, Johanne; Shi, Yan; Neveling, Kornelia; Buitelaar, Jan K.; Hoogman, Martine; Franke, Barbara; Klein, Marieke
    DNA methylation associated with persistent ADHD suggests TARBP1 as novel candidate
    In: Neuropharmacology Jg. 184 (2021) S. 108370
  • Budeus, Bettina; Kibler, Artur; Brauser, Martina; Homp, Ekaterina; Bronischewski, Kevin; Ross, J. Alexander; Görgens, Andre; Weniger, Marc; Dunst, Josefine; Kreslavsky, Taras; da Conceição Castro, Symone Vitoriano; Murke, Florian; Oakes, Christopher C.; Rusch, Peter; Andrikos, Dimitrios; Kern, Peter; Köninger, Angela; Lindemann, Monika; Johansson, Patricia; Hansen, Wiebke; Lundell, Anna-Carin; Rudin, Anna; Dürig, Jan; Giebel, Bernd; Hoffmann, Daniel; Küppers, Ralf; Seifert, Marc
    Human cord blood b cells differ from the adult counterpart by conserved ig repertoires and accelerated response dynamics
    In: The Journal of Immunology (JI) Jg. 206 (2021) Nr. 12, S. 2839 - 2851
  • Kibler, Artur; Budeus, Bettina; Homp, Ekaterina; Bronischewski, Kevin; Berg, Victoria; Sellmann, Ludger; Murke, Florian; Heinold, Andreas; Heinemann, Falko M.; Lindemann, Monika; Bekeredjian-Ding, Isabelle; Horn, Peter; Kirschning, Carsten Jürgen; Küppers, Ralf; Seifert, Marc
    Systematic memory B cell archiving and random display shape the human splenic marginal zone throughout life
    In: Journal of Experimental Medicine (JEM) Jg. 218 (2021) Nr. 4, S. e20201952
  • Johansson, Patricia; Klein-Hitpaß, Ludger; Budeus, Bettina; Kuhn, Matthias; Lauber, Chris; Seifert, Michael; Roeder, Ingo; Pförtner, Roman; Stuschke, Martin; Dührsen, Ulrich; Eckstein, Anja; Dürig, Jan; Küppers, Ralf
    Identifying genetic lesions in ocular adnexal extranodal marginal zone lymphomas of the malt subtype by whole genome, whole exome and targeted sequencing
    In: Cancers Jg. 12 (2020) Nr. 4, S. 986
  • Karimzadeh, Hadi; Kiraithe, Muthamia M.; Oberhardt, Valerie; Salimi Alizei, Elahe; Bockmann, Jan; Schulze zur Wiesch, Julian; Budeus, Bettina; Hoffmann, Daniel; Wedemeyer, Heiner; Cornberg, Markus; Krawczyk, Adalbert; Rashidi-Alavijeh, Jassin; Rodríguez-Frías, Francisco; Casillas, Rosario; Buti, Maria; Smedile, Antonina; Alavian, Seyed Moayed; Heinold, Andreas; Emmerich, Florian; Panning, Marcus; Gostick, Emma; Price, David A.; Timm, Jörg; Hofmann, Maike; Raziorrouh, Bijan; Thimme, Robert; Protzer, Ulrike; Roggendorf, Michael; Neumann-Haefelin, Christoph
    Mutations in Hepatitis D Virus Allow It to Escape Detection by CD8⁺ T Cells and Evolve at the Population Level
    In: Gastroenterology Jg. 156 (2019) Nr. 6, S. 1820 - 1833
  • Alavian, Seyed Moayed; Price, David A.; Panning, Marcus; Neumann-Haefelin, Christoph; Bockmann, Jan; Wiesch, Julian Schulze zur; Wedemeyer, Heiner; Heinold, Andreas; Alizei, Elahe Salimi; Timm, Jörg; Casillas, Rosario; Protzer, Ulrike; Raziorrouh, Bijan; Smedile, Antonina; Rodríguez-Frías, Francisco; Hoffmann, Daniel; Oberhardt, Valerie; Buti, Maria; Thimme, Robert; Roggendorf, Michael; Hofmann, Maike; Gostick, Emma; Budeus, Bettina; Emmerich, Florian; Kiraithe, Muthamia M.; Karimzadeh, Hadi
    Viral escape contributes to the failure of hepatitis D virus-specific CD8+ T-cells and drives evolution of HDV
    In: Journal of Hepatology Jg. 70 (2019) Nr. Suppl. 1, S. e21
  • Karimzadeh, Hadi; Kiraithe, Muthamia M.; Kosinska, Anna D.; Glaser, Manuel; Fiedler, Melanie; Oberhardt, Valerie; Alizei, Elahe Salimi; Hofmann, Maike; Mok, Juk Yee; Nguyen, Melanie; van Esch, Wim J.E.; Budeus, Bettina; Grabowski, Jan; Homs, Maria; Olivero, Antonella; Keyvani, Hossein; Rodríguez-Frías, Francisco; Tabernero, David; Buti, Maria; Heinold, Andreas; Alavian, Seyed Moayed; Bauer, Tanja; Wiesch, Julian Schulze zur; Raziorrouh, Bijan; Hoffmann, Daniel; Smedile, Antonina; Rizzetto, Mario; Wedemeyer, Heiner; Timm, Jörg; Antes, Iris; Neumann-Haefelin, Christoph; Protzer, Ulrike; Roggendorf, Michael
    Amino acid substitutions within HLA-B*27- restricted T cell epitopes prevent recognition by hepatitis delta virus-specific CD8⁺ T cells
    In: Journal of Virology Jg. 92 (2018) Nr. 13, S. e01891 - 17
  • Saeedghalati, Mohammadkarim; Farahpour, Farnoush; Budeus, Bettina; Lange, Anja; Westendorf, Astrid; Seifert, Marc; Küppers, Ralf; Hoffmann, Daniel
    Quantitative Comparison of Abundance Structures of Generalized Communities : from B-Cell Receptor Repertoires to Microbiomes
    In: PLoS Computational Biology Jg. 13 (2017) Nr. 1, e1005362
  • Riemenschneider, Mona; Heider, Dominik; Gorry, Paul R.; Kaiser, Rolf; Bayanolhagh, Saeed; Shirvani-Dastgerdi, Elham; Sierra, Saleta; Budeus, Bettina; Cash, Kieran Y.
    Genotypic Prediction of Co-receptor Tropism of HIV-1 Subtypes A and C
    In: Scientific Reports Jg. 6 (2016) S. 24883
  • Budeus, Bettina; Timm, Jörg; Hoffmann, Daniel
    SeqFeatR for the Discovery of Feature-Sequence Associations
    In: PLoS ONE Jg. 11 (2016) Nr. 1, S. e0146409
  • Kefalakes, Helenie; Budeus, Bettina; Walker, Andreas; Jochum, Christoph; Hilgard, Gudrun; Heinold, Andreas; Heinemann, Falko M.; Gerken, Guido; Hoffmann, Daniel; Timm, Jörg
    Adaptation of the Hepatitis B Virus Core Protein to CD8+ T-Cell Selection Pressure
    In: Hepatology Jg. 62 (2015) Nr. 1, S. 47 - 56
  • Lange, Anja; Jost, Steffen Oliver; Heider, Dominik; Bock, Christina; Budeus, Bettina; Schilling, Elmar; Strittmatter, Axel; Boenigk, Jens; Hoffmann, Daniel
    AmpliconDuo : a split-sample filtering protocol for high-throughput amplicon sequencing of microbial communities
    In: PLoS ONE Jg. 10 (2015) Nr. 11, S. e0141590
  • Budeus, Bettina; De Reynoso, Stefanie Schweigle; Przekopowitz, Martina; Hoffmann, Daniel; Seifert, Marc; Küppers, Ralf
    Complexity of the human memory B-cell compartment is determined by the versatility of clonal diversification in germinal centers
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 112 (2015) Nr. 38, S. E5281 - E5289
  • Dang, S.; Wang, Yan; Budeus, Bettina; Verheyen, Jens; Yang, R.; Hoffmann, Daniel
    Differential selection in HIV-1 gp120 between subtype B and East Asian variant B'
    In: Virologica Sinica Jg. 29 (2014) Nr. 1, S. 40 - 47
  • Skibbe, K.; Budeus, Bettina; Heinemann, Falko M.; Timmer, L.; Horn, Peter; van Esch, W.; Hoffmann, Daniel; Siemann, H.; Scherbaum, Norbert; Timm, Jörg
    HLA-B*27 is protective against HCV genotype 1 and 3 and associated with targeting of distinct genotype-specific CD8(+) cell epitopes
    In: Journal of Hepatology Jg. 60 (2014) Nr. Suppl. 1, S. 140
  • Qin, Bo; Budeus, Bettina; Cao, Liang; Wu, Chunchen; Wang, Yun; Zhang, Xiaoyong; Rayner, Simon; Hoffmann, Daniel; Lu, Mengji; Chen, Xinwen
    The amino acid substitutions rtP177G and rtF249A in the reverse transcriptase domain of hepatitis B virus polymerase reduce the susceptibility to tenofovir
    In: Antiviral Research Jg. 97 (2013) Nr. 2, S. 93 - 100
  • Abstracts

  • Fitzgerald, Donnacha; Roider, Tobias; Baertsch, Marc-A.; Vöhringer, Harald; Knoll, Mareike; Budeus, Bettina; Kibler, Artur; Mathioudaki, Anna; Caillé, Léandra; Li, Linsha; Mammen, Johannes; Seifert, Marc; Huber, Wolfgang; Dietrich, Sascha
    Single-Cell Multi-Omic and Spatial Analysis of Nodal B Cell Non-Hodgkin Lymphomas Reveals Plasticity in B Cell Maturation As a Driver of Intratumor Heterogeneity
    In: Blood Jg. 140 (2022) Nr. Supplement 1: 64th ASH Annual Meeting and Exposition, 10-13 December 2022, New Orleans, S. 752 - 753
  • Karimzadeh, H.; Budeus, Bettina; Kosinska, A.; Bauer, T.; Heinold, Andreas; Hoffmann, D.; Protzer, U.; Roggendorf, Michael
    Correlation of Mutations within HDV-Protein with HLA Backgrounds of Patients Leads to Identification of Novel CD8 T Cell Epitopes
    In: Journal of Hepatology Jg. 64 (2016) Nr. 2, Suppl., S. S361
  • Seifert, Marc; Przekopowitz, Martina; Schweigle, Stefanie; Budeus, Bettina; Taudien, Sarah; Lollies, Anna; Ronge, Viola; Sellmann, Ludger; Hillen, Uwe; Engler, Harald; Schedlowski, Manfred; Singer, Bernhard B.; Hoffmann, Daniel; Küppers, Ralf
    Functional Characterization and Clonal Composition of Human Post-germinal Center Memory B Cells
    In: Scandinavian Journal of Immunology Jg. 80 (2014) Nr. 3: The 18th germinal centre conferenceUddevalla, SwedenSeptember 11–14, 2014, Abstracts, S. 233
  • Beiträge in Sammelwerken und Tagungsbänden

  • Schnormeier, Ann-Kathrin; Budeus, Bettina
    Single Cell VDJ Sequencing of Normal and Malignant B and T Cells
    In: Lymphoma: Methods and Protocols / Küppers, Ralf (Hrsg.) 2025, S. 295 - 346
  • Dissertation

  • Budeus, Bettina;
    Statistical analysis of sequence populations in virology and immunology
    Duisburg, Essen (2017) xii, 154, A-33 Seiten
  • Poster / Posterbeiträge

  • Jehn, L; Berg, V; Kibler, Artur; Boerner, E; Wälscher, J; Budeus, Bettina; Seifert, M; Taube, Christian; Bonella, Francesco;
    Die durchflusszytometrische Untersuchung von T-Lymphozytensubpopulationen in der Ganzlungen-Lavage (GLL) bei der pulmonalen Alveolarproteinose : eine Pilot-Studie
    64. Kongress der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin, 20.–23.03.2024, Mannheim, Germany,
    In: Pneumologie Jg. 78 (2024) Nr. Suppl. 1, S. S11 - S12
  • Jehn, Lutz-Bernhard; Berg, Victoria; Kibler, Artur; Boerner, Eda; Waelscher, Julia; Budeus, Bettina; Seifert, Marc; Taube, Christian; Bonella, Francesco;
    Flow cytometric evaluation of whole lung lavage (WLL) fluid from patients with pulmonary alveolar proteinosis (PAP) : preliminary findings
    International Congress of the European Respiratory Society (ERS) 2023 ; 9 - 13 September 2023, Milan, Italy,
    In: European Respiratory Journal (ERJ) Jg. 62 (2023) Nr. Supplement 67: ERS International Congress 2023 abstracts, PA3946