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Dr. rer. nat. Florian Wirsdörfer

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Guberina, Nika; Wirsdörfer, Florian; Stuschke, Martin; Jendrossek, Verena
    Combined radiation- and immune checkpoint-inhibitor-induced pneumonitis : The challenge to predict and detect overlapping immune-related adverse effects from evolving laboratory biomarkers and clinical imaging
    In: Neoplasia: An International Journal for Oncology Research Jg. 39 (2023) 100892
    Online Volltext: dx.doi.org/ (Open Access)
  • Martins Nascentes Melo, Luiza; Herrera-Rios, Dayana; Hinze, Daniel; Löffek, Stefanie; Oezel, Irem; Turiello, Roberta; Klein, Juliane; Leonardelli, Sonia; Westedt, Isa-Vanessa; Al-Matary, Yahya; Egea-Rodriguez, Sara; Brenzel, Alexandra; Bau, Maja; Sucker, Antje; Hadaschik, Eva; Wirsdörfer, Florian; Hanenberg, Helmut; Uhlenbrock, Niklas; Rauh, Daniel; Poźniak, Joanna; Rambow, Florian; Marine, Jean-Christophe; Effern, Maike; Glodde, Nicole; Schadendorf, Dirk; Jablonska, Jadwiga; Hölzel, Michael; Helfrich, Iris
    Glucocorticoid activation by HSD11B1 limits T cell-driven interferon signaling and response to PD-1 blockade in melanoma
    In: Journal for ImmunoTherapy of Cancer Jg. 11 (2023) Nr. 4, e004150
    Online Volltext: dx.doi.org/ (Open Access)
  • Wenzek, Christina; Steinbach, Philine; Wirsdörfer, Florian; Sutter, Kathrin; Boehme, Julia D.; Geffers, Robert; Klopfleisch, Robert; Bruder, Dunja; Jendrossek, Verena; Buer, Jan; Westendorf, Astrid; Knuschke, Torben
    CD47 restricts antiviral function of alveolar macrophages during influenza virus infection
    In: iScience Jg. 25 (2022) Nr. 12, 105540
    Online Volltext: dx.doi.org/
  • Meyer, Alina V.; Klein, Diana; de Leve, Simone; Szymonowicz, Klaudia; Stuschke, Martin; Robson, Simon C.; Jendrossek, Verena; Wirsdörfer, Florian
    Host CD39 Deficiency Affects Radiation-Induced Tumor Growth Delay and Aggravates Radiation-Induced Normal Tissue Toxicity
    In: Frontiers in Oncology Jg. 10 (2020) S. 554883
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • de Leve, Simone; Wirsdörfer, Florian; Jendrossek, Verena
    Addendum: de Leve, S.; et al. The CD73/Ado System—A New Player in RT Induced Adverse Late Effects. Cancers 2019, 11, 1578
    In: Cancers Jg. 11 (2019) Nr. 12, S. 1898
    Online Volltext: dx.doi.org/ (Open Access)
  • Wiesemann, Alina; Ketteler, Julia; Slama, Alexis; Wirsdörfer, Florian; Hager, Thomas; Röck, Katharina; Engel, Daniel Robert; Fischer, Jens W.; Aigner, Clemens; Jendrossek, Verena; Klein, Diana
    Inhibition of Radiation-Induced Ccl2 Signaling Protects Lungs from Vascular Dysfunction and Endothelial Cell Loss
    In: Antioxidants and Redox Signaling Jg. 30 (2019) Nr. 2, S. 213 - 231
    Online Volltext: dx.doi.org/
  • de Leve, Simone; Wirsdörfer, Florian; Jendrossek, Verena
    Targeting the Immunomodulatory CD73/Adenosine System to Improve the Therapeutic Gain of Radiotherapy
    In: Frontiers in Immunology Jg. 10 (2019) S. 698
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • de Leve, Simone; Wirsdörfer, Florian; Jendrossek, Verena
    The CD73/Ado System - A New Player in RT Induced Adverse Late Effects
    In: Cancers Jg. 11 (2019) Nr. 10, S. 1578
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Wirsdörfer, Florian; de Leve, Simone; Jendrossek, Verena
    Combining Radiotherapy and Immunotherapy in Lung Cancer : Can We Expect Limitations Due to Altered Normal Tissue Toxicity?
    In: International Journal of Molecular Sciences (IJMS) Jg. 20 (2018) Nr. 1, S. 24
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Hlouschek, Julian; Ritter, Violetta; Wirsdörfer, Florian; Klein, Diana; Jendrossek, Verena; Matschke, Johann
    Targeting SLC25A10 alleviates improved antioxidant capacity and associated radioresistance of cancer cells induced by chronic-cycling hypoxia
    In: Cancer Letters Jg. 439 (2018) S. 24 - 38
    Online Volltext: dx.doi.org/
  • De Leve, Simone; Wirsdörfer, Florian; Cappuccini, Federica; Schütze, Alexandra; Meyer, Alina V.; Röck, Katharina; Thompson, Linda F.; Fischer, Jens W.; Stuschke, Martin; Jendrossek, Verena
    Loss of CD73 prevents accumulation of alternatively activated macrophages and the formation of prefibrotic macrophage clusters in irradiated lungs
    In: The FASEB Journal Jg. 31 (2017) Nr. 7, S. 2869 - 2880
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Klein, Diana; Steens, Jennifer; Wiesemann, Alina; Schulz, Florian; Kaschani, Farnusch; Röck, Katharina; Yamaguchi, Masahiro; Wirsdörfer, Florian; Kaiser, Markus; Fischer, Jens W.; Stuschke, Martin; Jendrossek, Verena
    Mesenchymal stem cell therapy protects lungs from radiation-induced endothelial cell loss by restoring superoxide dismutase 1 expression
    In: Antioxidants and Redox Signaling Jg. 26 (2017) Nr. 11, S. 563 - 582
    Online Volltext: dx.doi.org/ (Open Access)
  • Wirsdörfer, Florian; Jendrossek, Verena
    Modeling DNA damage-induced pneumopathy in mice : insight from danger signaling cascades
    In: Radiation Oncology Jg. 12 (2017) S. 142
    Online Volltext: dx.doi.org/ (Open Access)
  • Smirnov, Anna; Pohlmann, Stephanie; Nehring, Melanie; Ali, Shafaqat; Mann-Nüttel, Ritu; Scheu, Stefanie; Antoni, Anne-Charlotte; Hansen, Wiebke; Büettner, Manuela; Gardiasch, Miriam J.; Westendorf, Astrid; Wirsdörfer, Florian; Pastille, Eva; Dudda, Marcel; Flohe, Stefanie
    Sphingosine 1-Phosphate- and C-C Chemokine Receptor 2-Dependent Activation of CD4+ Plasmacytoid Dendritic Cells in the Bone Marrow Contributes to Signs of Sepsis-Induced Immunosuppression
    In: Frontiers in Immunology Jg. 8 (2017) 1622
    Online Volltext: dx.doi.org/ (Open Access)
  • Wirsdörfer, Florian; Bangen, Jörg-Martin; Pastille, Eva; Schmitz, Daniel; Flohé, Sascha; Schumak, Beatrix; Flohe, Stefanie
    Dendritic Cell-Like Cells Accumulate in Regenerating Murine Skeletal Muscle after Injury and Boost Adaptive Immune Responses Only upon a Microbial Challenge
    In: PLoS ONE Jg. 11 (2016) Nr. 5, S. e0155870
    Online Volltext: dx.doi.org/ (Open Access)
  • Wirsdörfer, Florian; de Leve, Simone; Cappuccini, Federica; Eldh, Therese; Meyer, Alina V; Gau, Eva; Thompson, Linda F; Chen, Ning-Yuan; Karmouty-Quintana, Harry; Fischer, Ute; Kasper, Michael; Klein, Diana; Ritchey, Jerry W; Blackburn, Michael R; Westendorf, Astrid; Stuschke, Martin; Jendrossek, Verena
    Extracellular Adenosine Production by ecto-5'-Nucleotidase (CD73) Enhances Radiation-Induced Lung Fibrosis
    In: Cancer Research Jg. 76 (2016) Nr. 10, S. 3045 - 3056
    Online Volltext: dx.doi.org/ (Open Access)
  • Wirsdörfer, Florian; Jendrossek, Verena
    The Role of Lymphocytes in Radiotherapy-Induced Adverse Late Effects in the Lung
    In: Frontiers in Immunology Jg. 7 (2016) S. 591
    Online Volltext: dx.doi.org/ (Open Access)
  • Klein, Diana; Schmetter, Alexandra; Imsak, Roze; Wirsdörfer, Florian; Unger, Kristian; Jastrow, Holger; Stuschke, Martin; Jendrossek, Verena
    Therapy with multipotent mesenchymal stromal cells protects lungs from radiation-induced injury and reduces the risk of lung metastasis
    In: Antioxidants and Redox Signaling Jg. 24 (2016) Nr. 2, S. 53 - 69
    Online Volltext: dx.doi.org/
  • Pastille, Eva; Pohlmann, Stephanie; Wirsdörfer, Florian; Reib, Anna; Flohe, Stefanie
    A disturbed interaction with accessory cells upon opportunistic infection with Pseudomonas aeruginosa contributes to an impaired IFN-γ production of NK cells in the lung during sepsis-induced immunosuppression
    In: Innate Immunity Jg. 21 (2015) Nr. 2, S. 115 - 126
    Online Volltext: dx.doi.org/
  • Wirsdörfer, Florian; Bangen, Jörg-Martin; Pastille, Eva; Hansen, Wiebke; Flohe, Stefanie
    Breaking the co-operation between bystander T-cells and natural killer cells prevents the development of immunosuppression after traumatic skeletal muscle injury in mice
    In: Clinical Science Jg. 128 (2015) Nr. 11, S. 825 - 838
    Online Volltext: dx.doi.org/ (Open Access)
  • Ring, Sabine; Pushkarevskaya, Anna; Schild, Hansjörg; Probst, Hans Christian; Jendrossek, Verena; Wirsdörfer, Florian; Ledent, Catherine; Robson, Simon Christopher; Enk, Alexander H.; Mahnke, Karsten
    Regulatory T Cell–Derived Adenosine Induces Dendritic Cell Migration through the Epac-Rap1 Pathway
    In: The Journal of Immunology (JI) Jg. 194 (2015) Nr. 8, S. 3735 - 3744
    Online Volltext: dx.doi.org/
  • De Haan, Jacco Juri; Pastille, Eva; Wirsdörfer, Florian; Lubbers, Tim; Greve, Jan Willem M; Zhang, Yang; Buurman, Wim A.; Flohe, Stefanie
    Lipid-rich enteral nutrition improves the defense against an opportunistic infection during polymicrobial sepsis
    In: Shock Jg. 41 (2014) Nr. 2, S. 109 - 114
    Online Volltext: dx.doi.org/
  • Wirsdörfer, Florian; Cappuccini, Federica; Niazman, Musca; Leve, Simone de; Westendorf, Astrid; Lüdemann, Lutz; Stuschke, Martin; Jendrossek, Verena
    Thorax irradiation triggers a local and systemic accumulation of immunosuppressive CD4+ FoxP3+ regulatory T cells
    In: Radiation Oncology Jg. 9 (2014) Nr. 1, 98
    Online Volltext: dx.doi.org/ (Open Access)
  • Wirsdörfer, Florian; Cappucini, F.; Drabczyk, M.; Stuschke, Martin; Hagemann, T.; Jendrossek, Verena
    Thorax irradiation triggers local and systemic immune changes
    In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 189 (2013) Nr. Suppl. 1, S. 125 - 126

    • Abstracts

  • Herz, Andreas; Guberina, Maja; Pöttgen, Christoph; Freisleben, Fabian; Hlouschek, Julian; Jendrossek, Verena; Wirsdörfer, Florian; Gauler, Thomas; Fischedick, Gerrit; Hoffmann, Christian; Stuschke, Martin; Guberina, Nika
    Gibt es unterschiedliche Verteilungsmuster zwischen strahlen- oder immuninduzierten Pneumonitiden in Abhängigkeit von der Dosisverteilung?
    In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 199 (2023) Nr. Suppl. 1, S. S167 - S168
    Online Volltext: dx.doi.org/ (Open Access)
  • Wirsdörfer, Florian; Gockeln, Lena; De Leve, Simone; Stuschke, Martin; Jendrossek, Verena;
    CD4+T-Lymphocytes impact macrophage polarization in irradiated lungs and promote progression of radiation-induced lung fibrosis
    26. Jahrestagung der Deutschen Gesellschaft für Radioonkologie (DEGRO) ; 24. - 28. Juni 2020, Wiesbaden, Germany,
    In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 196 (2020) Nr. 1 Supplement: Abstracts DEGRO 2020, S. S26 - S27
    Online Volltext: dx.doi.org/ (Open Access)
  • Wirsdörfer, Florian; Gockeln, Lena; de Leve, Simone; Stuschke, Martin; Jendrossek, Verena;
    Cross talk between T lymphocytes and macrophages promotes progression of radiation induced lung fibrosis
    Annual Meeting of the American Association for Cancer Research 2020; 2020 Apr 27-28 and Jun 22-24; Philadelphia, USA,
    In: Cancer Research Jg. 80 (2020) Nr. Suppl. 16, S. LB - 071
    Online Volltext: dx.doi.org/
  • deLeve, Simone; Wirsdörfer, Florian; Meyer, A. V.; Thompson, L. F.; Jendrossek, Verena;
    The immunoregulatory CD73/Adenosine system limits successful radiotherapy
    24. Jahrestagung der Deutschen Gesellschaft für Radioonkologie, 21. Juni 2018 - 24. Juni 2018, Leipzig,
    In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 194 (2018) Nr. 1 Supplement, Abstracts DEGRO 2018, S. 95
    Online Volltext: dx.doi.org/ (Open Access)
  • Wirsdörfer, Florian; de Leve, S.; Cappuccini, F.; Mayer, A.; Klein, Diana; Eldh, T.; Fischer, U.; Kasper, M.; Karmouty-Quintana, H.; Blackburn, M.; Stuschke, Martin; Thompson, L. F.; Jendrossek, Verena;
    Loss or therapeutic inhibition of extracellular adenosine production by ecto-5 -nucleotidase (CD73) attenuates radiation-induced lung fibrosis
    21. Jahrestagung der Deutschen Gesellschaft für Radioonkologie, 25. Juni 2015, Hamburg,
    In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 191 (2015) Nr. Suppl.1, S. 14 - S15
    Online Volltext: dx.doi.org/
  • Jendrossek, Verena; Wirsdörfer, Florian; Simone, D. L.; Cappuccini, F.; Therese, E.; Meyer, A.; Karmouty-Quintana, H.; Thompson, L.; Fischer, U.; Kasper, M.; Klein, Diana; Ritchey, J.; Westendorf, Astrid; Stuschke, Martin;
    Loss or therapeutic inhibition of extracellular adenosine production by ecto-5 -nucleotidase(CD73) attenuates radiation-induced lung fibrosis
    European Cancer Congress (ECC 2015), 25.-29.09.2015, Wien,
    In: European Journal of Cancer (EJC) Jg. 51 (2015) Nr. Supplement 3, S. S117 - S118
    Online Volltext: dx.doi.org/
  • Wirsdörfer, Florian; Niazman, M.; Cappuccini, F.; De Leve, S.; Westendorf, Astrid; Lüdemann, Lutz; Stuschke, Martin; Jendrossek, Verena;
    Whole thorax irradiation initiates a local and systemic accumulation of immunosuppressive FoxP3+regulatory T cells
    23rd Biennial Congress of the European Association for Cancer Research, 05.–08.07.2014, München,
    In: European Journal of Cancer (EJC) Jg. 50 (2014) Nr. Suppl. 5, S. S223
    Online Volltext: dx.doi.org/
  • Cappuccini, F.; Wirsdörfer, Florian; Maniati, E.; Hagemann, T.; Westendorf, Astrid; Stuschke, Martin; Jendrossek, Verena
    Lymphocytes play a role in radiation-induced pneumopathy
    In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 188 (2012) Nr. Suppl.1: Abstract-Band DEGRO 2014, S. 126 - 127
    Online Volltext: dx.doi.org/
  • Wirsdörfer, Florian; Bangen, Jörg-Martin; Schmitz, Daniel; Schade, Fritz Ulrich; Flohe, Stefanie
    Dendritic cells that infiltrate damaged skeletal muscle tissue reverse impaired Th-cell responses after trauma
    In: Inflammation Research Jg. 59 (2010) Nr. Suppl. 1, S. S42
    Online Volltext: dx.doi.org/