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DKFZ-Abteilung für Translationale Neuroonkologie am WTZ - Universitätsklinikum Essen
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Professorinnen/Professoren, Experimentelle Immunologie und Bildgebung
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2024 SS
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2021 SS
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Cranioencephalic functional lymphoid units in glioblastomaIn: Nature Medicine (2024) in pressOnline Volltext: dx.doi.org/ (Open Access)
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KDM5B predicts temozolomide-resistant subclones in glioblastomaIn: iScience Jg. 27 (2024) Nr. 1, 108596Online Volltext: dx.doi.org/ (Open Access)
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Predictors and surgical outcome of hemorrhagic metastatic brain malignanciesIn: Journal of Neuro-Oncology Jg. 169 (2024) Nr. 1, S. 165 - 173Online Volltext: dx.doi.org/ (Open Access)
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The Role of Fibroblast Activation Protein in Glioblastoma and Gliosarcoma : A Comparison of Tissue, ⁶⁸Ga-FAPI-46 PET Data, and Survival DataIn: Journal of Nuclear Medicine (JNM) Jg. 65 (2024) Nr. 8, S. 1217 - 1223Online Volltext: dx.doi.org/
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The influence of radiological tumor growth pattern on sino‑nasal health in pituitary adenomasIn: Oncology Letters Jg. 27 (2024) Nr. 3, 125Online Volltext: dx.doi.org/ (Open Access)
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Treatment Strategies for Glioblastoma in the Elderly : What Should We Focus on Compared to Younger PatientsIn: Cancers Jg. 16 (2024) Nr. 6, 1231Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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A Sequential Targeting Strategy Interrupts AKT-Driven Subclone-Mediated Progression in GlioblastomaIn: Clinical Cancer Research Jg. 29 (2023) Nr. 2, S. 488 - 500Online Volltext: dx.doi.org/ (Open Access)
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A novel serum extracellular vesicle protein signature to monitor glioblastoma tumor progressionIn: International Journal of Cancer Jg. 152 (2023) Nr. 2, S. 308 - 319Online Volltext: dx.doi.org/ (Open Access)
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Are we providing best available care to newly diagnosed glioblastoma patients? : Systematic review of phase III trials in newly diagnosed glioblastoma 2005-2022In: Neuro-Oncology Advances Jg. 5 (2023) Nr. 1, vdad105Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Feasibility and tolerability of trofosfamide and etoposide in progressive glioblastomaIn: Neuro-Oncology Advances Jg. 5 (2023) Nr. 1, vdad090Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Heparins are potent inhibitors of ectonucleotide pyrophosphatase/phospho-diesterase-1 (NPP1) : a promising target for the immunotherapy of cancerIn: Frontiers in Immunology Jg. 14 (2023) 1173634Online Volltext: dx.doi.org/ (Open Access)
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Individual glioblastoma cells harbor both proliferative and invasive capabilities during tumor progressionIn: Neuro-Oncology Jg. 25 (2023) Nr. 12, S. 2150 - 2162Online Volltext: dx.doi.org/
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Location of Recurrences after Trimodality Treatment for Glioblastoma with Respect to the Delivered Radiation Dose Distribution and Its Influence on PrognosisIn: Cancers Jg. 15 (2023) Nr. 11, 2982Online Volltext: dx.doi.org/ (Open Access)
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Precision neuro-oncology : A pilot analysis of personalized treatment in recurrent gliomaIn: Journal of Cancer Research and Clinical Oncology Jg. 149 (2023) Nr. 7, S. 3513 - 3526Online Volltext: dx.doi.org/ (Open Access)
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Surface Chemistry and Specific Surface Area Rule the Efficiency of Gold Nanoparticle Sensitizers in Proton TherapyIn: Chemistry - A European Journal Jg. 29 (2023) Nr. 50, e202301260Online Volltext: dx.doi.org/ (Open Access)
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TERT expression is associated with metastasis from thin primaries, exhausted CD4+ T cells in melanoma and with DNA repair across cancer entitiesIn: PLoS ONE Jg. 18 (2023) Nr. 7, e0281487Online Volltext: dx.doi.org/ (Open Access)
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Telemedicine in Neuro-Oncology : An Evaluation of Remote Consultations during the COVID-19 PandemicIn: Cancers Jg. 15 (2023) Nr. 16, 4054Online Volltext: dx.doi.org/ (Open Access)
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First multicentric real-life experience with the combination of CCNU and temozolomide in newly diagnosed MGMT promoter methylated IDH wildtype glioblastomaIn: Neuro-Oncology Advances Jg. 4 (2022) Nr. 1, S. vdac137Online Volltext: dx.doi.org/ (Open Access)
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Machine Learning Applications for Differentiation of Glioma from Brain Metastasis : A Systematic ReviewIn: Cancers Jg. 14 (2022) Nr. 6, 1369Online Volltext: dx.doi.org/ (Open Access)
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Progranulin mediates immune evasion of pancreatic ductal adenocarcinoma through regulation of MHCI expressionIn: Nature Communications Jg. 13 (2022) Nr. 1, 156Online Volltext: dx.doi.org/ (Open Access)
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The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumorsIn: Nature Communications Jg. 13 (2022) Nr. 1, 4061Online Volltext: dx.doi.org/ (Open Access)
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Case Report : Pseudomeningeosis and Demyelinating Metastasis-Like Lesions From Checkpoint Inhibitor Therapy in Malignant MelanomaIn: Frontiers in Oncology Jg. 11 (2021) S. 637185Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Dosimetric impact of the positioning variation of tumor treating field electrodes in the PriCoTTF-phase I/II trialIn: Journal of Applied Clinical Medical Physics Jg. 22 (2021) Nr. 1, S. 242 - 250Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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How about levetiracetam in glioblastoma? An institutional experience and meta‐analysisIn: Cancers Jg. 13 (2021) Nr. 15, 3770Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Leptomeningeal disease from melanoma : Poor prognosis despite new therapeutic modalitiesIn: European Journal of Cancer (EJC) Jg. 148 (2021) S. 395 - 404Online Volltext: dx.doi.org/
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Machine learning-based differentiation between multiple sclerosis and glioma WHO II°-IV° using O-(2-[18F] fluoroethyl)-L-tyrosine positron emission tomographyIn: Journal of Neuro-Oncology Jg. 152 (2021) S. 325 - 332Online Volltext: dx.doi.org/
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Preoperative and early postoperative seizures in patients with glioblastoma : two sides of the same coin?In: Neuro-Oncology Advances Jg. 3 (2021) Nr. 1, vdaa158Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Tumor-associated hematopoietic stem and progenitor cells positively linked to glioblastoma progressionIn: Nature Communications Jg. 12 (2021) Nr. 1, 3895Online Volltext: dx.doi.org/ (Open Access)
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Analysis of serum mirna in glioblastoma patients : Cd44-based enrichment of extracellular vesicles enhances specificity for the prognostic signatureIn: International Journal of Molecular Sciences (IJMS) Jg. 21 (2020) Nr. 19, S. 7211Online Volltext: dx.doi.org/ (Open Access)
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Challenging Implications of Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids Syndrome with an Atypical Presentation : Report of Two CasesIn: World Neurosurgery Jg. 143 (2020) S. 507 - 512.e1Online Volltext: dx.doi.org/
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Characterization of a dual BET/HDAC inhibitor for treatment of pancreatic ductal adenocarcinomaIn: International Journal of Cancer Jg. 147 (2020) Nr. 10, S. 2847 - 2861Online Volltext: dx.doi.org/ (Open Access)
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Combined radiotherapy and concurrent tumor treating fields (TTFields) for glioblastoma : Dosimetric consequences on non-coplanar IMRT as initial results from a phase i trialIn: Radiation Oncology Jg. 15 (2020) Nr. 1, S. 83Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Drug repositioning of antiretroviral ritonavir for combinatorial therapy in glioblastomaIn: European Journal of Cancer (EJC) Jg. 140 (2020) S. 130 - 139Online Volltext: dx.doi.org/
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Exosome/microvesicle content is altered in leucine-rich repeat kinase 2 mutant induced pluripotent stem cell-derived neural cellsIn: Journal of Comparative Neurology Jg. 528 (2020) Nr. 7, S. 1203 - 1215Online Volltext: dx.doi.org/
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Olfactory function as an independent prognostic factor in glioblastomaIn: Neurology Jg. 94 (2020) Nr. 5, S. e529 - e537Online Volltext: dx.doi.org/
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Plasma next generation sequencing and droplet digital-qpcr-based quantification of circulating cell-free rna for noninvasive early detection of cancerIn: Cancers Jg. 12 (2020) Nr. 2, S. 353Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Tumour Treating Fields (TTFields) in combination with lomustine and temozolomide in patients with newly diagnosed glioblastomaIn: Journal of Cancer Research and Clinical Oncology Jg. 146 (2020) Nr. 3, S. 787 - 792Online Volltext: dx.doi.org/
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3D extracellular matrix microenvironment in bioengineered tissue models of primary pediatric and adult brain tumorsIn: Nature Communications Jg. 10 (2019) S. 4529Online Volltext: dx.doi.org/ (Open Access)
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Comparison of L-Methyl-11C-Methionine PET With Magnetic Resonance Spectroscopy in Detecting Newly Diagnosed GliomaIn: Clinical Nuclear Medicine Jg. 44 (2019) Nr. 6, S. e375 - e381Online Volltext: dx.doi.org/
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Hybrid 11C-MET PET/MRI Combined With "Machine Learning" in Glioma Diagnosis According to the Revised Glioma WHO Classification 2016In: Clinical Nuclear Medicine Jg. 44 (2019) Nr. 3, S. 214 - 220Online Volltext: dx.doi.org/
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Longitudinal heterogeneity in glioblastoma : moving targets in recurrent versus primary tumorsIn: Journal of Translational Medicine Jg. 17 (2019) Nr. 1, S. 96Online Volltext: dx.doi.org/ (Open Access)
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Regorafenib in patients with recurrent high-grade astrocytomaIn: Journal of Cancer Research and Clinical Oncology Jg. 145 (2019) Nr. 4, S. 1037 - 1042Online Volltext: dx.doi.org/
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Sequence-dependent cross-resistance of combined radiotherapy plus BRAFV⁶⁰⁰E inhibition in melanomaIn: European Journal of Cancer (EJC) Jg. 109 (2019) S. 137 - 153Online Volltext: dx.doi.org/
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Simultaneous primary cancer occurrence of melanoma and pulmonary adenocarcinoma in leptomeningeal metastases: a case reportIn: BMC Cancer Jg. 19 (2019) Nr. 1, S. 995Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Recurrent pseudoprogression in isocitrate dehydrogenase 1 mutant glioblastomaIn: Journal of Clinical Neuroscience Jg. 53 (2018) S. 255 - 258Online Volltext: dx.doi.org/
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Functional Subclone profiling for prediction of treatment-induced intratumor population shifts and discovery of rational drug combinations in human glioblastomaIn: Clinical Cancer Research Jg. 23 (2017) Nr. 2, S. 562 - 574Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Unsupervised consensus cluster analysis of [18F]-fluoroethyl- L-tyrosine positron emission tomography identified textural features for the diagnosis of pseudoprogression in high-grade gliomaIn: OncoTarget Jg. 8 (2017) Nr. 5, S. 8294 - 8304Online Volltext: dx.doi.org/ (Open Access)
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Dynamic O-(2-[18F]fluoroethyl)-L-tyrosine PET imaging for the detection of checkpoint inhibitor-related pseudoprogression in melanoma brain metastasesIn: Neuro-Oncology Jg. 18 (2016) Nr. 10, S. 1462 - 1464Online Volltext: dx.doi.org/
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Late Pseudoprogression in Glioblastoma : Diagnostic Value of Dynamic O-(2-[¹⁸ F]fluoroethyl)-L-Tyrosine PETIn: Clinical Cancer Research Jg. 22 (2016) Nr. 9, S. 2190 - 2196Online Volltext: dx.doi.org/
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Phase I trial of dovitinib (TKI258) in recurrent glioblastomaIn: Journal of Cancer Research and Clinical Oncology Jg. 142 (2016) Nr. 7, S. 1581 - 1589Online Volltext: dx.doi.org/
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Carmustine (BCNU) plus Teniposide (VM26) in recurrent malignant gliomaIn: Oncology Jg. 86 (2014) Nr. 5-6, S. 369 - 372Online Volltext: dx.doi.org/
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Anticancer effects of niclosamide in human glioblastomaIn: Clinical Cancer Research Jg. 19 (2013) Nr. 15, S. 4124 - 4136Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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FLAIR-Only progression in bevacizumab-treated relapsing glioblastoma does not predict short survivalIn: Oncology Jg. 85 (2013) Nr. 3, S. 191 - 195Online Volltext: dx.doi.org/
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Vemurafenib for leptomeningeal melanomatosisIn: Journal of Clinical Oncology (JCO) Jg. 31 (2013) Nr. 11,Online Volltext: dx.doi.org/
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c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotypeIn: Proceedings of the National Academy of Sciences of the United States of America Jg. 108 (2011) Nr. 24, S. 9951 - 9956Online Volltext: dx.doi.org/ (Open Access)
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Residual tumor cells are unique cellular targets in glioblastomaIn: Annals of Neurology Jg. 68 (2010) Nr. 2, S. 264 - 269Online Volltext: dx.doi.org/ (Open Access)
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Temporally restricted substrate interactions direct fate and specification of neural precursors derived from embryonic stem cellsIn: Proceedings of the National Academy of Sciences of the United States of America Jg. 103 (2006) Nr. 29, S. 11063 - 11068Online Volltext: dx.doi.org/ (Open Access)
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Phenotypic and functional characterization of adult brain neuropoiesisIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 102 (2005) Nr. 26, S. 9353 - 9358Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Functional integration of embryonic stem cell-derived neurons in hippocampal slice culturesIn: Journal of Neuroscience Jg. 23 (2003) Nr. 18, S. 7075 - 7083Online Volltext: dx.doi.org/ (Open Access)
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Marrow-mindedness : a perspective on neuropoiesisIn: Trends in Neurosciences: TINS Jg. 22 (1999) Nr. 8, S. 348 - 357Online Volltext: dx.doi.org/
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68Ga-NeoB PET for Glioma and Breast Cancer : First Results from a Prospective Observational Trial
Annual Congress of the European Association of Nuclear Medicine, 9-13 September 2023 Vienna, Austria,In: European Journal of Nuclear Medicine and Molecular Imaging Jg. 50 (2023) Nr. 1 supplement, S. S265Online Volltext: dx.doi.org/ (Open Access) -
Decoding glioblastoma survival : unraveling the prognostic potential of olfactory function in a prospective observational study
28th Annual Scientific Meeting of the Society-for-Neuro-Oncology (SNO); NOV 15-19, 2023; Vancouver, Canada,In: Neuro-Oncology Jg. 25 (2023) Nr. Suppl. 5, S. v92 - v92Online Volltext: dx.doi.org/ -
Fet pet sensitivity in primary brain tumors according to cns who 2021 : value and pitfalls in presurgical implementationIn: Neuro-Oncology Jg. 25 (2023) Nr. Suppl. 5, S. v204 - v205Online Volltext: dx.doi.org/
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Immunogenicity of an additional dose of covid-19 vaccine in fully vaccinated patients with glioma to evaluate new national vaccination guidelines : a prospective cohort studyIn: Neuro-Oncology Jg. 25 (2023) Nr. Suppl. 5, S. v63 - v64Online Volltext: dx.doi.org/
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Investigating safety and efficacy of ttfields prior and concomitant to radiotherapy in newly diagnosed glioblastoma : First results of the pricottf phase I/II trial
28th Annual Scientific Meeting of the Society-for-Neuro-Oncology (SNO); NOV 15-19, 2023; Vancouver, Canada,In: Neuro-Oncology Jg. 25 (2023) Nr. Suppl. 5, S. v91 - v92Online Volltext: dx.doi.org/ -
Predicting and targeting clonally expanding, tmz-resistant tumor cells in glioblastoma
28th Annual Scientific Meeting of the Society-for-Neuro-Oncology (SNO); NOV 15-19, 2023; Vancouver, Canada,In: Neuro-Oncology Jg. 25 (2023) Nr. Suppl. 5, S. v110 - v110Online Volltext: dx.doi.org/ -
Safety and efcacy of TTFields therapy prior and concomitant to radiotherapy in newly diagnosed glioblastoma : the PriCoTTF phase I/II trialIn: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 199 (2023) Nr. Suppl. 1, S. S32Online Volltext: dx.doi.org/ (Open Access)
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Temporal muscle thickness as a prognostic marker in a real-life cohort of newly diagnosed MGMT promoter methylated glioblastoma patients : a multicentric imaging analysisIn: Neuro-Oncology Jg. 25 (2023) Nr. Suppl. 5, S. v192 - v193Online Volltext: dx.doi.org/
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A Investigating safety and efficacy of TTFields prior and concomitant to radiotherapy in newly diagnosed glioblastoma : The PriCoTTF phase I/II trialIn: Neuro-Oncology Jg. 24 (2022) Nr. Suppl. 2, S. ii14 - ii14Online Volltext: dx.doi.org/ (Open Access)
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Combination of Trofosfamide and Etoposide in Recurrent GliomaIn: Neuro-Oncology Jg. 24 (2022) Nr. Suppl. 2, S. ii89 - ii89Online Volltext: dx.doi.org/ (Open Access)
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BIOM-24. PROTEIN SURFACE SIGNATURE ON SERUM EXTRACELLULAR VESICLES FOR NON-INVASIVE DETECTION OF TUMOR PROGRESSION IN GLIOBLASTOMA PATIENTS
2021 Society for Neuro-Oncology’s 26th Annual Scientific Meeting and Education Day,In: Neuro-Oncology Jg. 23 (2021) Nr. Supplement_6, S. vi15 - vi16Online Volltext: dx.doi.org/ (Open Access) -
PRICOTTF trial : A phase I/II trial of TTfields prior and concomitant to radiotherapy in newly diagnosed glioblastomaIn: Neuro-Oncology Jg. 23 (2021) Nr. Suppl. 2, S. 50
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PriCoTTF Trial : A Phase I//II Trial of TTFields Prior and Concomitant to Radiotherapy in newly diagnosed Glioblastoma
2021 Society for Neuro-Oncology’s 26th Annual Scientific Meeting and Education Day,In: Neuro-Oncology Jg. 23 (2021) Nr. Supplement_6, S. vi68 - vi68Online Volltext: dx.doi.org/ (Open Access) -
Analysis of serum mirna in glioblastoma patients : Targeted erichment of extracellular vesicles enhances specificity for prognostic signatureIn: Neuro-Oncology Jg. 22 (2020) Nr. Supplement 2, S. 10Online Volltext: dx.doi.org/ (Open Access)
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Deep learning enabled prediction of isocitrate dehydrogenase mutation status from digtial histapathology data in glioblastomaIn: Neuro-Oncology Jg. 22 (2020) Nr. Supplement 2, S. ii167Online Volltext: dx.doi.org/ (Open Access)
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Evaluation der dosimetrischen Auswirkungen der geometrischen Variation der Tumor Treating Field (TTF) Elektroden-Positionierung in der PriCoTTF-Phase I/II Studie
26. Jahrestagung der Deutschen Gesellschaft für Radioonkologie (DEGRO) ; 24. Juni - 28. Juni 2020, Wiesbaden, Germany,In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 196 (2020) Nr. 1 Supplement: Abstracts DEGRO 2020, S. S65Online Volltext: dx.doi.org/ (Open Access) -
PriCoTTF Trial : A phase I/II trial of TTFields prior and concomitant to radiotherapy in newly diagnosed glioblastoma
26. Jahrestagung der Deutschen Gesellschaft für Radioonkologie (DEGRO) ; 24. - 28. Juni 2020, Wiesbaden, Germany,In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 196 (2020) Nr. 1 Supplement: Abstracts DEGRO 2020, S. S74Online Volltext: dx.doi.org/ (Open Access) -
Pricottf trial : a phase I/II trial of ttfields prior and concomitant to radiotherapy in newly diagnosed glioblastomaIn: Neuro-Oncology Jg. 22 (2020) Nr. Supplement_2, S. ii61 - ii61Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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ACTR-49. PriCoTTF: A PHASE I/II TRIAL OF TUMOR TREATING FIELDS PRIOR AND CONCOMITANT TO RADIOTHERAPY IN NEWLY DIAGNOSED GLIOBLASTOMA
23rd Annual Scientific Meeting and Education Day of the Society for Neuro-Oncology November 15 – 18, 2018 New Orleans, USA,In: Neuro-Oncology Jg. 20 (2018) Nr. suppl_6, S. vi22 - vi23Online Volltext: dx.doi.org/ (Open Access) -
CBMT-17. NOVEL APPROACH OF UTILISING SERUM/PLASMA EV AND CELL-FREE RNA FOR TREATMENT MONITORING IN GLIOBLASTOMA PATIENTSIn: Neuro-Oncology Jg. 20 (2018) Nr. suppl_6, S. vi35 - vi36Online Volltext: dx.doi.org/ (Open Access)
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HOUT-30. TUMOR TREATING FIELDS (TTFIELDS) IN COMBINATION WITH LOMUSTINE (CCNU) AND TEMOZOLOMIDE (TMZ) IN PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA (GBM)
23rd Annual Scientific Meeting and Education Day of the Society for Neuro-Oncology November 15 – 18, 2018 New Orleans, USA,In: Neuro-Oncology Jg. 20 (2018) Nr. suppl_6, S. vi119 - vi120Online Volltext: dx.doi.org/ (Open Access) -
NIMG-32. COMPARISON OF L-METHYL-11C-METHIONINE POSITRON EMISSION TOMOGRAPHY WITH MAGNETIC RESONANCE SPECTROSCOPY IN DETECTING NEWLY DIAGNOSED GLIOMA
23rd Annual Scientific Meeting and Education Day of the Society for Neuro-Oncology November 15 – 18, 2018 New Orleans, USA,In: Neuro-Oncology Jg. 20 (2018) Nr. suppl_6, S. vi182 - vi183Online Volltext: dx.doi.org/ (Open Access)