01.02.2024 - 17:47:33

How Cells migrate

Two new papers on cell migration were published by Prof. Dr. Perihan Nalbant (MB) in cooperation with Dr. Leif Dehmelt (Chemistry and Chemical Biology, TU Dortmund). For efficient cell migration dynamic cell shape changes need to be coordinated. Most cell types form protrusions in the front and a retracting tail. In these two papers the groups used TIRF microscopy and translocation sensors to measure Rho GTPase activity which play a key role in the spatio-temporal coordination of the relevant cytoskeletal dynamics.