Publikationen
2024
1. Treatment of Staphylococcus aureus infection with sphingosine in ex vivo perfused and ventilated lungs.
Liu Y, Wu Y, Leukers L, Schimank K, Wilker J, Wissmann A, Rauen U, Pizanis N, Taube C, Koch A, Gulbins E, Kamler M.
J Heart Lung Transplant 43(1):100-110 (2024)
2023
1. Composition of ex vivo perfusion solutions and kinetics define differential cytokine/chemokine secretion in a porcine cardiac arrest model of lung preservation.
Radomsky L, Koch A, Olbertz C, Liu Y, Beushausen K, Keil J, Rauen U, Falk CS, Kühne JF, Kamler M.
Front Cardiovasc Med 10:1245618 (2023)
2022
1. Custodiol-MP for ex vivo lung perfusion - A comparison in a porcine model of donation after circulatory determination of death.
Kalka K, Keldenich Z, Carstens H, Walter B, Rauen U, Ruhparwar A, Weymann A, Kamler M, Reiner G, Koch A.
Mol Med 28(1):13 (2022)
2. Recovery from cold-induced mitochondrial fission in endothelial cells requires reconditioning temperatures of ≥ 25◦C.
Quiring L, Caponi L, Schwan D, Rech A, Rauen U.
Front Transplant 1:1044551 (2022)
3. Antimicrobial effects of inhaled sphingosine against Pseudomonas aeruginosa in isolated ventilated and perfused pig lungs.
Carstens H, Kalka K, Verhaegh R, Schumacher F, Soddemann M, Wilker B, Keitsch S, Sehl C, Kleuser B, Hübler M, Rauen U, Becker AK, Koch A, Gulbins E, Kamler M.
PLoS One. 17(7):e0271620 (2022)
4. Characterisation of cold-induced mitochondrial fission in porcine aortic endothelial cells.
Quiring L, Walter B, Lohaus N, Schwan D, Rech A, Dlugos A, Rauen U.
Mol Med 28(1):13 (2022)
5. HTK-N as a new preservation solution for human kidney preservation: Results of a pilot randomized controlled clinical phase II trial in living donor transplantation.
Hoyer DP, Benkö T, Gallinat A, Lefering R, Kaths M, Kribben A, Korth J, Rauen U, Treckmann JW, Paul A.
Clin Transplant 36(3):e14543 (2022)
2021
1. Use of the new preservation solution Custodiol-MP for ex vivo reconditioning of kidney grafts.
von Horn C, Wilde B, Rauen U, Paul A, Minor T.
Artif Organs 45(9):1117-1123. (2021)
2. Inhaled sphingosine has no adverse side effects in isolated ventilated and perfused pig lungs.
Carstens H, Kalka K, Verhaegh R, Schumacher F, Soddemann M, Wilker B, Keitsch S, Sehl C, Kleuser B, Wahlers T, Reiner G, Koch A, Rauen U, Gulbins E, Kamler M.
Sci Rep 11(1):18607 (2021)
2020
1. Use of modified Custodiol-N as perfusion solution in ex vivo lung perfusion.
Olbertz C, Pizanis N, Bäumker H, Kalka K, Aigner C, Rauen U, Nolte I, Kamler M, Koch A.
Am J Transl Res 12(1):153-161 (2020)
2019
1. Effects of immediate versus delayed ex-vivo lung perfusion in a porcine cardiac arrest donation model.
Olbertz C, Pizanis N, Bäumker H, Becker S, Aigner C, Rauen U, Nolte I, Kamler M, Koch A.
Int J Artif Organs. 42(7):362-369 (2019)
2018
1. Methylene Blue Treatment of Grafts During Cold Ischemia Time Reduces the Risk of Hepatitis C Virus Transmission.
Helfritz FA, Bojkova D, Wanders V, Kuklinski N, Westhaus S, von Horn C, Rauen U, Gallinat A, Baba HA, Skyschally A, Swoboda S, Kinast V, Steinmann E, Heusch G, Minor T, Meuleman P, Paul A, Ciesek S.
J Infect Dis 20;218(11):1711-1721 (2018)
2017
1. Resveratrol Does Not Protect from Ischemia-Induced Acute Kidney Injury in an in Vivo Rat Model.
Bienholz A, Mae Pang R, Guberina H, Rauen U, Witzke O, Wilde B, Petrat F, Feldkamp T, Kribben A.
Kidney Blood Press Res. 42(6):1090-1103 (2017)
2. Characterization of injury in isolated rat proximal tubules during cold incubation and rewarming.
Bienholz A, Walter B, Pless-Petig G, Guberina H, Kribben A, Witzke O, Rauen U.
PLoS One 3;12(7):e0180553 (2017)
2016
1. Controlled Oxygenated Rewarming of Cold Stored Livers Prior to Transplantation: First Clinical Application of a New Concept.
Hoyer DP, Mathé Z, Gallinat A, Canbay AC, Treckmann JW, Rauen U, Paul A, Minor T.
Transplantation 100(1):147-52 (2016)
2015
1. Minor T, Paul A, Efferz P, Wohlschlaeger J, Rauen U, Gallinat A.
Kidney transplantation after oxygenated machine perfusion with Custodiol-N solution.
Transpl Int. 28(9):1102-8 (2015)
2014
1. Hoyer DP, Gallinat A, Swoboda S, Wohschlaeger J, Rauen U, Paul A, Minor T.
Influence of oxygen concentration during hypothermic machine perfusion on porcine kidneys from donation after circulatory death.
Transplantation 98, 944-50 (2014)
2. Hoyer DP, Gallinat A, Swoboda S, Wohschlaeger J, Rauen U, Paul A, Minor T.
Subnormothermic machine perfusion for preservation of porcine kidneys in a donation after circulatory death model.
Transpl Int 27, 1097-106 (2014)
2013
1. Sydor S, Gu Y, Schlattjan M, Bechmann LP, Rauen U, Best J, Paul A, Baba HA, Sowa JP, Gerken G, Canbay A.
Steatosis does not impair liver regeneration after partial hepatectomy.
Lab Invest 93, 20-30 (2013)
2. Gallinat A, Lüer B, Swoboda S, Rauen U, Paul A, Minor T.
Use of the new preservation solution Custodiol-N supplemented with dextran for hypothermic machine perfusion of the kidney. Cryobiology 66, 131-5 (2013)
3. Hagemann S, Wohlschlaeger J, Bertram S, Levkau B, Musacchio A, Conway EM, Moellmann D, Kneiseler G, Pless-Petig G, Lorenz K, Sitek B, Baba HA.
Loss of Survivin influences liver regeneration and is associated with impaired Aurora B function.
Cell Death Differ 20, 834-44 (2013)
2012
1. Pizanis N, Petrov A, Heckmann J, Wiswedel I, Wohlschläger J, de Groot H, Jakob H, Rauen U, Kamler M.
A new preservation solution for lung transplantation. Evaluation in a porcine transplantation model.
J Heart Lung Transplant 31, 310-7 (2012)
2. Liu Q, Bruns H, Schultze D, Xue Y, Zorn M, Flechtenmacher C, Straub BK, Rauen U, Schemmer P.
HTK-N, a modified HTK solution, decreases preservation injury in a model of microsteatotic rat liver transplantation.
Langenbecks Arch Surg 397, 1323-31 (2012)
2011
1. Wu K, Türk TR, Rauen U, Su S, Feldkamp T, de Groot H, Wiswedel I, Baba HA, Kribben A, Witzke O.
Prolonged cold storage using a new histidine-tryptophan-ketoglutarate-based preservation solution in isogeneic cardiac mouse grafts.
Eur Heart J 32, 509-516 (2011)
2. Fingas CD, Wu S, Gu Y, Wohlschlaeger J, Scherag A, Dahmen U, Paul A, de Groot H, Rauen U.
Assessment of a chloride-poor vs. a chloride-containing modified HTK solution in a rat liver transplantation model.
Liver Transpl Jun;17(6):650-60 (2011)
2010
1. Benko T, Frede S, Gu Y, Best J, Baba HA, Schlaak JF, de Groot H, Fandrey J, Rauen U.
Glycine pretreatment ameliorates liver injury after partial hepatectomy in the rat.
J Invest Surg 23, 12-20 (2010)
2. Stegemann J, Hirner A, Rauen U, Minor T.
Use of a new modified HTK solution for machine preservation of marginal liver grafts.
J Surg Res 160, 155-162 (2010)
3. Heuer M, Reinhardt R, Kneiseler G, Würzinger P, Zou X, Hua F, Jian F, Paul A, Kaiser GM.
Liver transplantation in swine without venovenous bypass.
Eur Surg Res 45, 20-25 (2010)
2009
1. Stegemann J, Hirner A, Rauen U, Minor T.
Gaseous oxygen persufflation of oxygenated machine perfusion with Custodiol-N for long-term preservation of ischemic rat livers?
Cryobiology 58, 45-51 (2009)
2. Wu S, Wohlschlaeger J, de Groot H, Rauen U.
Evaluation of a modified HTK solution containing the new iron chelator LK 614 in an isolated rat liver perfusion model.
J Invest Surg 22, 340-347 (2009)
3. Bramey T, Freitag P, Fandrey J, Rauen U, Pamp K, Erhard J, Frede S, de Groot H, Petrat F.
No evidence for protective erythropoietin alpha signalling in rat hepatocytes.
BMC Gastroenterology 9, 26 (2009)
2008
Extent of liver resection modulates the activation of transcription factors and the production of cytokines involved in liver regeneration.
World J Gastroenterol 14, 7093-7100 (2008).
Erythropoietin treatment improves liver regeneration and survival in rat models of extended liver resection and living donor liver transplantation.
Transplantation 86, 1578-85 (2008).