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Universitätsprofessor/in, Institut für Zellbiologie (Tumorforschung)
Aktuelle Veranstaltungen
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2024 WS
- Modern Biomedicine/Beispiele biologischer Forschung (Teil 1)
- Molekular- und Zellbiologie für Biomediziner
- Laborpraktikum I für Masterstudenten der medizinischen Biologie (WP)
- Molekular- und Zellbiologie für Biomediziner (PV)
- Laborpraktikum II für Masterstudenten der medizinischen Biologie (WP)
- Laborpraktikum III für Masterstudenten der medizinischen Biologie (WP)
- Anleitung zu selbständigen wissenschaftlichen Arbeiten (*)
- Neue Literatur (Zellbiologie, experimentelle Krebsforschung) (*)
- Seminar für Zellbiologie und experimentelle Krebsforschung (mit Gastsprechern) (*)
- Mitarbeiterseminar in englischer Sprache (Lymphome)
- Mitarbeiterseminar in englischer Sprache (Immunologie)
- Mitarbeiterseminar zur Besprechung aktueller Arbeiten
Vergangene Veranstaltungen (max. 10)
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2024 SS
- Neue Literatur der Zell- und Molekularbiologie für Med. Biologen
- Vorlesung Immunologie für medizinische Biologen (Masters)
- Seminar Neue Literatur der Zell- und Molekularbiologie für med. Biologen (Bachelor) Gruppe II
- Seminar Molekulare Immunologie für medizinische Biologen (Master)
- Praktikum Zell- und Molekularbiologie für med. Biologen (Bachelor) (PV)
- Seminar Neue Literatur der Zell- und Molekularbiologie für med. Biologen (Bachelor) Gruppe I
- Mitarbeiterseminar zur Besprechung aktueller Arbeiten
- Anleitung zu selbständigen wissenschaftlichen Arbeiten (*)
- Neue Literatur (Zellbiologie, experimentelle Krebsforschung) (*)
- Seminar für Zellbiologie und experimentelle Krebsforschung (mit Gastsprechern) (*)
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Advances in Hodgkin lymphoma researchIn: Trends in Molecular Medicine (2024) in pressOnline Volltext: dx.doi.org/ (Open Access)
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An atlas of cells in the human tonsilIn: Immunity Jg. 57 (2024) Nr. 2, S. 379 - 399.e18Online Volltext: dx.doi.org/ (Open Access)
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Checkpoint blockade therapy in Hodgkin lymphoma : improved response through combination with JAK inhibitionIn: Signal Transduction and Targeted Therapy Jg. 9 (2024) Nr. 1, 250Online Volltext: dx.doi.org/ (Open Access)
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Distinct t(14;19) translocation patterns in atypical chronic lymphocytic leukemia and marginal zone lymphomasIn: Haematologica / The Hematology Journal Jg. 109 (2024) Nr. 2, S. 376 - 378Online Volltext: dx.doi.org/ (Open Access)
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Mapping T cell landscapes in B cell lymphomasIn: Nature Cell Biology Jg. 26 (2024) Nr. 3, S. 323 - 324Online Volltext: dx.doi.org/
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Single-cell analysis of a bi-clonal chronic lymphocytic leukemia reveals two clones with distinct gene expression patternIn: Leukemia and Lymphoma (2024) in pressOnline Volltext: dx.doi.org/ (Open Access)
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Analyses of non-coding somatic drivers in 2,658 cancer whole genomesIn: Nature Jg. 578 (2023) Nr. 7793, S. 102 - 111Online Volltext: dx.doi.org/
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Author Correction : Analyses of non-coding somatic drivers in 2,658 cancer whole genomesIn: Nature Jg. 614 (2023) S. E40Online Volltext: dx.doi.org/ (Open Access)
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Author Correction : The evolutionary history of 2,658 cancersIn: Nature Jg. 614 (2023) S. E42Online Volltext: dx.doi.org/
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Author Correction : Genomic basis for RNA alterations in cancerIn: Nature Jg. 614 (2023) Nr. 7948, S. E37Online Volltext: dx.doi.org/
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Author Correction : Butler enables rapid cloud-based analysis of thousands of human genomesIn: Nature Biotechnology Jg. 41 (2023) Nr. 4, S. 577Online Volltext: dx.doi.org/
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Author Correction : Patterns of somatic structural variation in human cancer genomesIn: Nature Jg. 614 (2023) Nr. 7948, S. E38Online Volltext: dx.doi.org/ (Open Access)
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Author Correction: : The repertoire of mutational signatures in human cancerIn: Nature Jg. 614 (2023) S. E41Online Volltext: dx.doi.org/ (Open Access)
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Author Correction: Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencingIn: Nature Genetics Jg. 55 (2023) Nr. 6, 1076Online Volltext: dx.doi.org/ (Open Access)
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Author Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancersIn: Nature Genetics Jg. 55 (2023) Nr. 6, S. 1078Online Volltext: dx.doi.org/ (Open Access)
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Author Correction: Disruption of chromatin folding domains by somatic genomic rearrangements in human cancerIn: Nature Genetics Jg. 55 (2023) Nr. 6, S. 1079Online Volltext: dx.doi.org/ (Open Access)
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Author Correction: Pan-cancer analysis of whole genomesIn: Nature Jg. 614 (2023) Nr. 7948, S. E39Online Volltext: dx.doi.org/ (Open Access)
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Author Correction: Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotranspositionIn: Nature Genetics Jg. 55 (2023) Nr. 6, 1080Online Volltext: dx.doi.org/ (Open Access)
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B-cell receptor reactivity against Rothia mucilaginosa in nodular lymphocyte-predominant Hodgkin lymphomaIn: Haematologica / The Hematology Journal Jg. 108 (2023) Nr. 12, S. 3347 - 3358Online Volltext: dx.doi.org/ (Open Access)
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Clonal composition and differentiation stage of human CD30⁺ B cells in reactive lymph nodesIn: Frontiers in Immunology Jg. 14 (2023) 1208610Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencingIn: Nature Genetics Jg. 52 (2023) S. 331 - 341Online Volltext: dx.doi.org/ (Open Access)
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Comprehensive molecular characterization of mitochondrial genomes in human cancersIn: Nature Genetics Jg. 52 (2023) S. 342 - 352Online Volltext: dx.doi.org/ (Open Access)
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Disruption of chromatin folding domains by somatic genomic rearrangements in human cancerIn: Nature Genetics Jg. 52 (2023) Nr. 3, S. 294 - 305Online Volltext: dx.doi.org/ (Open Access)
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Focal structural variants revealed by whole genome sequencing disrupt the histone demethylase KDM4C in B-cell lymphomasIn: Haematologica / The Hematology Journal Jg. 108 (2023) Nr. 2, S. 543 - 554Online Volltext: dx.doi.org/ (Open Access)
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Genomic basis for RNA alterations in cancerIn: Nature Jg. 578 (2023) Nr. 7793, S. 129 - 136Online Volltext: dx.doi.org/
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Human IgM–expressing memory B cellsIn: Frontiers in Immunology Jg. 14 (2023) 1308378Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotranspositionIn: Nature Genetics Jg. 52 (2023) Nr. 3, S. 306 - 319Online Volltext: dx.doi.org/ (Open Access)
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Patterns of somatic structural variation in human cancer genomesIn: Nature Jg. 578 (2023) Nr. 7793, S. 112 - 121Online Volltext: dx.doi.org/
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Publisher Correction: Epigenome-wide analysis of T-cell large granular lymphocytic leukemia identifies BCL11B as a potential biomarkerIn: Clinical Epigenetics Jg. 15 (2023) Nr. 1, 3Online Volltext: dx.doi.org/ (Open Access)
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The landscape of viral associations in human cancersIn: Nature Genetics (2023) Nr. 52, S. 320 - 330Online Volltext: dx.doi.org/ (Open Access)
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The repertoire of mutational signatures in human cancerIn: Nature Jg. 578 (2023) Nr. 7793, S. 94 - 101Online Volltext: dx.doi.org/ (Open Access)
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Transcriptional reprogramming by mutated IRF4 in lymphomaIn: Nature Communications Jg. 14 (2023) Nr. 1, 6947Online Volltext: dx.doi.org/ (Open Access)
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Author Correction : Pathway and network analysis of more than 2500 whole cancer genomesIn: Nature Communications Jg. 13 (2022) 7566Online Volltext: dx.doi.org/ (Open Access)
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Author Correction : Combined burden and functional impact tests for cancer driver discovery using DriverPowerIn: Nature Communications Jg. 13 (2022) 7571Online Volltext: dx.doi.org/ (Open Access)
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Author Correction : Integrative pathway enrichment analysis of multivariate omics dataIn: Nature Communications Jg. 13 (2022) 7570Online Volltext: dx.doi.org/ (Open Access)
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Author Correction : A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patternsIn: Nature Communications Jg. 13 (2022) 7573Online Volltext: dx.doi.org/ (Open Access)
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Author Correction : Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSigIn: Nature Communications Jg. 13 (2022) 7567Online Volltext: dx.doi.org/ (Open Access)
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Author Correction : Divergent mutational processes distinguish hypoxic and normoxic tumoursIn: Nature Communications Jg. 13 (2022) 7569Online Volltext: dx.doi.org/ (Open Access)
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Author Correction : High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterationsIn: Nature Communications Jg. 13 (2022) 7572Online Volltext: dx.doi.org/ (Open Access)
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Author Correction : Inferring structural variant cancer cell fractionIn: Nature Communications Jg. 13 (2022) 7568Online Volltext: dx.doi.org/ (Open Access)
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Author Correction : Genomic footprints of activated telomere maintenance mechanisms in cancerIn: Nature Communications Jg. 13 (2022) 7574Online Volltext: dx.doi.org/ (Open Access)
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Distinct Chemokine Receptor Expression Profiles in De Novo DLBCL, Transformed Follicular Lymphoma, Richter's Trans-Formed DLBCL and Germinal Center B-CellsIn: International Journal of Molecular Sciences (IJMS) Jg. 23 (2022) Nr. 14,Online Volltext: dx.doi.org/ (Open Access)
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Epigenome-wide analysis of T-cell large granular lymphocytic leukemia identifies BCL11B as a potential biomarkerIn: Clinical Epigenetics Jg. 14 (2022) Nr. 1, 148Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Loss of function mutations of BCOR in classical Hodgkin lymphomaIn: Leukemia and Lymphoma Jg. 63 (2022) Nr. 5, S. 1080 - 1090Online Volltext: dx.doi.org/
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The Biology of Ocular Adnexal Marginal Zone LymphomasIn: Cancers Jg. 14 (2022) Nr. 5, 1264Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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The Splenic Marginal Zone in Children Is Characterized by a Subpopulation of CD27-Negative, Lowly IGHV-Mutated B CellsIn: Frontiers in Immunology Jg. 13 (2022) 825619Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Context-dependent regulation of immunoglobulin mutagenesis by p53In: Molecular Immunology Jg. 138 (2021) S. 128 - 136Online Volltext: dx.doi.org/
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Human cord blood b cells differ from the adult counterpart by conserved ig repertoires and accelerated response dynamicsIn: The Journal of Immunology (JI) Jg. 206 (2021) Nr. 12, S. 2839 - 2851Online Volltext: dx.doi.org/ (Open Access)
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Impact of a faulty germinal center reaction on the pathogenesis of primary diffuse large b cell lymphoma of the central nervous systemIn: Cancers Jg. 13 (2021) Nr. 24, 6334Online Volltext: dx.doi.org/ (Open Access)
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Molecular biology of Hodgkin lymphomaIn: Leukemia Jg. 35 (2021) Nr. 4, S. 968 - 981Online Volltext: dx.doi.org/ (Open Access)
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Mutational mechanisms shaping the coding and noncoding genome of germinal center derived B-cell lymphomasIn: Leukemia Jg. 35 (2021) S. 2002 - 2016Online Volltext: dx.doi.org/ (Open Access)
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PLK1-dependent phosphorylation restrains EBNA2 activity and lymphomagenesis in EBV-infected miceIn: EMBO Reports (2021) e53007Online Volltext: dx.doi.org/ (Open Access)
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Sugar-modified B-cell receptors in DLBCLIn: Blood Jg. 138 (2021) Nr. 17, S. 1512 - 1514Online Volltext: dx.doi.org/ (Open Access)
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Systematic memory B cell archiving and random display shape the human splenic marginal zone throughout lifeIn: Journal of Experimental Medicine (JEM) Jg. 218 (2021) Nr. 4, S. e20201952Online Volltext: dx.doi.org/ (Open Access)
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The life of B cells according to JEMIn: Journal of Experimental Medicine (JEM) Jg. 218 (2021) Nr. 5, S. e20210647Online Volltext: dx.doi.org/ (Open Access)
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The process of somatic hypermutation increases polyreactivity for central nervous system antigens in primary central nervous system lymphomaIn: Haematologica / The Hematology Journal Jg. 106 (2021) Nr. 3, S. 708 - 717Online Volltext: dx.doi.org/ (Open Access)
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UMI or not UMI, that is the question for scRNA-seq zero-inflationIn: Nature Biotechnology Jg. 39 (2021) Nr. 2, S. 158 - 159Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patternsIn: Nature Communications Jg. 11 (2020) 728Online Volltext: dx.doi.org/ (Open Access)
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Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samplesIn: Nature Communications Jg. 11 (2020) Nr. 1, S. 6232Online Volltext: dx.doi.org/ (Open Access)
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Combined burden and functional impact tests for cancer driver discovery using DriverPowerIn: Nature Communications Jg. 11 (2020) 734Online Volltext: dx.doi.org/ (Open Access)
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Divergent mutational processes distinguish hypoxic and normoxic tumoursIn: Nature Communications Jg. 11 (2020) 737Online Volltext: dx.doi.org/ (Open Access)
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Genomic and epigenomic insights into the origin, pathogenesis, and clinical behavior of mantle cell lymphoma subtypesIn: Blood Jg. 136 (2020) Nr. 12, S. 1419 - 1432Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Genomic footprints of activated telomere maintenance mechanisms in cancerIn: Nature Communications Jg. 11 (2020) 733Online Volltext: dx.doi.org/ (Open Access)
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High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterationsIn: Nature Communications Jg. 11 (2020) 736Online Volltext: dx.doi.org/ (Open Access)
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Identifying genetic lesions in ocular adnexal extranodal marginal zone lymphomas of the malt subtype by whole genome, whole exome and targeted sequencingIn: Cancers Jg. 12 (2020) Nr. 4, 986Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Inferring structural variant cancer cell fractionIn: Nature Communications Jg. 11 (2020) 730Online Volltext: dx.doi.org/ (Open Access)
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Integrative pathway enrichment analysis of multivariate omics dataIn: Nature Communications Jg. 11 (2020) 735Online Volltext: dx.doi.org/ (Open Access)
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Lymphocyte predominant cells detect Moraxella catarrhalis-derived antigens in nodular lymphocyte-predominant Hodgkin lymphomaIn: Nature Communications Jg. 11 (2020) Nr. 1, S. 2465Online Volltext: dx.doi.org/ (Open Access)
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Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLLIn: Genome Medicine Jg. 12 (2020) Nr. 1, 29Online Volltext: dx.doi.org/ (Open Access)
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Pan-cancer analysis of whole genomesIn: Nature Jg. 578 (2020) Nr. 7793, S. 82 - 93Online Volltext: dx.doi.org/ (Open Access)
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Pathway and network analysis of more than 2500 whole cancer genomesIn: Nature Communications Jg. 11 (2020) 729Online Volltext: dx.doi.org/ (Open Access)
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Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSigIn: Nature Communications Jg. 11 (2020) 731Online Volltext: dx.doi.org/ (Open Access)
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Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samplesIn: Nature Communications Jg. 11 (2020) Nr. 1, S. 4748Online Volltext: dx.doi.org/ (Open Access)
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Role of Specific B-Cell Receptor Antigens in LymphomagenesisIn: Frontiers in Oncology Jg. 10 (2020) S. 604685Online Volltext: dx.doi.org/ (Open Access)
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Sex differences in oncogenic mutational processesIn: Nature Communications Jg. 11 (2020) Nr. 1, S. 4330Online Volltext: dx.doi.org/ (Open Access)
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The Genomic Landscape of HIV-Associated Plasmablastic LymphomaIn: Blood Cancer Discovery Jg. 1 (2020) Nr. 1, S. 23 - 25Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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γδ T-cell receptors derived from breast cancer-infiltrating T lymphocytes mediate antitumor reactivityIn: Cancer Immunology Research Jg. 8 (2020) Nr. 4, S. 530 - 543Online Volltext: dx.doi.org/
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CD30 expression in neoplastic T cells of follicular T cell lymphoma is a helpful diagnostic tool in the differential diagnosis of Hodgkin lymphomaIn: Modern Pathology Jg. 32 (2019) Nr. 1, S. 37 - 47Online Volltext: dx.doi.org/ (Open Access)
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CD81 as target for B cell lymphomasIn: Journal of Experimental Medicine (JEM) Jg. 216 (2019) Nr. 7, S. 1469 - 1470Online Volltext: dx.doi.org/ (Open Access)
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Fibroblasts in nodular sclerosing classical Hodgkin lymphoma are defined by a specific phenotype and protect tumor cells from brentuximab-Vedotin induced injuryIn: Cancers Jg. 11 (2019) Nr. 11, Article-No: 1687Online Volltext: dx.doi.org/ (Open Access)
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Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphomaIn: Nature Communications Jg. 10 (2019) Nr. 1, S. 1459Online Volltext: dx.doi.org/ (Open Access)
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JUNB, DUSP2, SGK1, SOCS1 and CREBBP are frequently mutated in T-cell/histiocyte-rich large B-cell lymphomaIn: Haematologica / The Hematology Journal Jg. 104 (2019) Nr. 2, S. 330 - 337Online Volltext: dx.doi.org/ (Open Access)
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MDM4 Is Targeted by 1q Gain and Drives Disease in Burkitt LymphomaIn: Cancer Research Jg. 79 (2019) Nr. 12, S. 3125 - 3138Online Volltext: dx.doi.org/ (Open Access)
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Migration properties distinguish tumor cells of classical hodgkin lymphoma from anaplastic large cell lymphoma cellsIn: Cancers Jg. 11 (2019) Nr. 10, S. 1484Online Volltext: dx.doi.org/ (Open Access)
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An oncogenic axis of STAT-mediated BATF3 upregulation causing MYC activity in classical Hodgkin lymphoma and anaplastic large cell lymphomaIn: Leukemia Jg. 32 (2018) Nr. 1, S. 92 - 101Online Volltext: dx.doi.org/
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Biased IGH VDJ gene repertoire and clonal expansions in B cells of chronically hepatitis C virus–infected individualsIn: Blood Jg. 131 (2018) Nr. 5, S. 546 - 557Online Volltext: dx.doi.org/ (Open Access)
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CD83 in Hodgkin lymphomaIn: Haematologica / The Hematology Journal Jg. 103 (2018) Nr. 4, S. 561 - 562Online Volltext: dx.doi.org/ (Open Access)
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Critical influences on the pathogenesis of follicular lymphomaIn: Blood Jg. 131 (2018) Nr. 21, S. 2297 - 2306Online Volltext: dx.doi.org/ (Open Access)
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Ectopic expression of transcription factor BATF3 induces B-cell lymphomas in a murine B-cell transplantation modelIn: OncoTarget Jg. 9 (2018) Nr. 22, S. 15942 - 15951Online Volltext: dx.doi.org/ (Open Access)
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Expression profile of translation initiation factor eIF2B5 in diffuse large B-cell lymphoma and its correlation to clinical outcome.In: Blood Cancer Journal Jg. 8 (2018) Nr. 9, S. 79Online Volltext: dx.doi.org/ (Open Access)
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Human CD30⁺ B cells represent a unique subset related to Hodgkin lymphoma cellsIn: The Journal of Clinical Investigation (JCI) Jg. 128 (2018) Nr. 7, S. 2996 - 3007Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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IG-MYC⁺ neoplasms with precursor B-cell phenotype are molecularly distinct from Burkitt lymphomasIn: Blood Jg. 132 (2018) Nr. 21, S. 2280 - 2285Online Volltext: dx.doi.org/ (Open Access)
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SAMHD1 is recurrently mutated in T-cell prolymphocytic leukemiaIn: Blood Cancer Journal Jg. 8 (2018) Nr. 1, 11Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Complex Immune Evasion Strategies in Classical Hodgkin LymphomaIn: Cancer Immunology Research Jg. 5 (2017) Nr. 12, S. 1122 - 1132Online Volltext: dx.doi.org/
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Concepts in mature T-cell lymphomas – highlights from an international joint symposium on T-cell immunology and oncologyIn: Leukemia and Lymphoma Jg. 58 (2017) Nr. 4, S. 788 - 796Online Volltext: dx.doi.org/
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Quantitative Comparison of Abundance Structures of Generalized Communities : from B-Cell Receptor Repertoires to MicrobiomesIn: PLoS Computational Biology Jg. 13 (2017) Nr. 1, e1005362Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Structure and diversification of immunoglobulin genes in African Burkitt lymphomaIn: Blood Advances Jg. 1 (2017) Nr. 16, S. 1259 - 1260Online Volltext: dx.doi.org/ (Open Access)
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TET2 mutations in B cells of patients affected by angioimmunoblastic T-cell lymphomaIn: The Journal of Pathology Jg. 242 (2017) Nr. 2, S. 129 - 133Online Volltext: dx.doi.org/
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A strong host response and lack of MYC expression are characteristic for diffuse large B cell lymphoma transformed from nodular lymphocyte predominant Hodgkin lymphomaIn: OncoTarget Jg. 7 (2016) Nr. 44, S. 72197 - 72210Online Volltext: dx.doi.org/ (Open Access)
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Alterations of microRNA and microRNA-regulated messenger RNA expression in germinal center B-cell lymphomas determined by integrative sequencing analysisIn: Haematologica / The Hematology Journal Jg. 101 (2016) Nr. 11, S. 1380 - 1389Online Volltext: dx.doi.org/ (Open Access)
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DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemiaIn: Nature Genetics Jg. 48 (2016) Nr. 3, S. 253 - 264Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphomaIn: Blood Jg. 128 (2016) Nr. 23, S. 2666 - 2670Online Volltext: dx.doi.org/ (Open Access)
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Highly recurrent mutations of SGK1, DUSP2 and JUNB in nodular lymphocyte predominant Hodgkin lymphomaIn: Leukemia Jg. 30 (2016) Nr. 4, S. 844 - 853Online Volltext: dx.doi.org/
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Hodgkin lymphoma : Pathology and biologyIn: Seminars in Hematology Jg. 53 (2016) Nr. 3, S. 139 - 147Online Volltext: dx.doi.org/
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Mikrofluidik-Chip-Architekturen für eine Zell-Sortieranlage basierend auf der Elektrowetting-TechnologieIn: Technisches Messen: tm Jg. 83 (2016) Nr. 5, S. 274 - 288Online Volltext: dx.doi.org/
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NF-κB deregulation in Hodgkin lymphomaIn: Seminars in Cancer Biology Jg. 39 (2016) S. 32 - 39Online Volltext: dx.doi.org/
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Novel IGH and MYC Translocation Partners in Diffuse Large B-Cell LymphomasIn: Genes, Chromosomes and Cancer Jg. 55 (2016) Nr. 12, S. 932 - 943Online Volltext: dx.doi.org/
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Recurrent alterations of TNFAIP3 (A20) in T-cell large granular lymphocytic leukemiaIn: International Journal of Cancer Jg. 138 (2016) Nr. 1, S. 121 - 124Online Volltext: dx.doi.org/ (Open Access)
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Recurrent mutations in NF-κB pathway components, KMT2D, and NOTCH1/2 in ocular adnexal MALT-type marginal zone lymphomasIn: OncoTarget Jg. 7 (2016) Nr. 38, S. 62627 - 62639Online Volltext: dx.doi.org/ (Open Access)
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The International Human Epigenome Consortium : A Blueprint for Scientific Collaboration and DiscoveryIn: Cell Jg. 167 (2016) Nr. 5, S. 1145 - 1149Online Volltext: dx.doi.org/ (Open Access)
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The role of t cells in the microenvironment of hodgkin lymphomaIn: Journal of Leukocyte Biology (JLB) Jg. 99 (2016) Nr. 1, S. 45 - 50Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Tumor-infiltrating HLA-matched CD4(+) T cells retargeted against Hodgkin and Reed-Sternberg cellsIn: OncoImmunology Jg. 5 (2016) Nr. 6, e1160186Online Volltext: dx.doi.org/ (Open Access)
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A large fraction of human tonsillar B cells expressing CD27 are germinal center B cellsIn: Immunology and Cell Biology Jg. 93 (2015) Nr. 5, S. 429 - 430Online Volltext: dx.doi.org/
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Alterations of the CD58 gene in classical Hodgkin lymphomaIn: Genes, Chromosomes and Cancer Jg. 54 (2015) Nr. 10, S. 638 - 645Online Volltext: dx.doi.org/
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Analysis of mechanisms of malignant transformation in TP53 wild-type burkitts lymphoma by integration of molecular and functional genomics dataIn: Haematologica / The Hematology Journal Jg. 100 (2015) Nr. Suppl. 1, S. 105Online Volltext (Open Access)
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Characterization of genomic imbalances in diffuse large B-cell lymphoma by detailed SNP-chip analysisIn: International Journal of Cancer Jg. 136 (2015) Nr. 5, S. 1033 - 1042Online Volltext: dx.doi.org/ (Open Access)
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Complexity of the human memory B-cell compartment is determined by the versatility of clonal diversification in germinal centersIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 112 (2015) Nr. 38, S. E5281 - E5289Online Volltext: dx.doi.org/ (Open Access)
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DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional controlIn: Nature Genetics Jg. 47 (2015) Nr. 11, S. 1316 - 1325Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Functional capacities of human igm memory b cells in early inflammatory responses and secondary germinal center reactionsIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 112 (2015) Nr. 6, S. E546 - E555Online Volltext: dx.doi.org/ (Open Access)
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Genomic and epigenomic co-evolution in follicular lymphomasIn: Leukemia Jg. 29 (2015) Nr. 2, S. 456 - 463Online Volltext: dx.doi.org/
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IRAK4 inhibition to shut down TLR signaling in autoimmunity and MyD88-dependent lymphomasIn: Journal of Experimental Medicine (JEM) Jg. 212 (2015) Nr. 13, S. 2184Online Volltext: dx.doi.org/ (Open Access)
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MINCR is a MYC-induced lncRNA able to modulate MYC's transcriptional network in Burkitt lymphoma cellsIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 112 (2015) Nr. 38, S. E5261 - E5270Online Volltext: dx.doi.org/ (Open Access)
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Potential role of hypoxia in early stages of Hodgkin lymphoma pathogenesisIn: Haematologica / The Hematology Journal Jg. 100 (2015) Nr. 10, S. 1320 - 1326Online Volltext: dx.doi.org/ (Open Access)
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Progressive Epigenetic Programming during B Cell Maturation Is Reflected in a Continuum of Epigenetic Disease Phenotypes in Chronic Lymphocytic LeukemiaIn: Blood Jg. 126 (2015) Nr. 23, S. 2436Online Volltext: dx.doi.org/
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Progressive epigenetic programming during B cell maturation yields a continuum of clonal disease phenotypes with distinct etiologies in chronic lymphocytic leukemiaIn: Clinical Cancer Research Jg. 21 (2015) Nr. 17 Suppl., S. B25 - B25Online Volltext: dx.doi.org/
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Immunoglobulin repertoire of Primary lymphomas of the central nervous systemIn: Journal of Neuropathology & Experimental Neurology (JNEN) Jg. 73 (2014) Nr. 12, S. 1116 - 1125Online Volltext: dx.doi.org/ (Open Access)
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Intrahepatic B-cell follicles of chronically hepatitis C virus-infected individuals lack signs of an ectopic germinal center reactionIn: European Journal of Immunology Jg. 44 (2014) Nr. 6, S. 1842 - 1850Online Volltext: dx.doi.org/
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Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphomaIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 111 (2014) Nr. 42, S. E4513 - E4522Online Volltext: dx.doi.org/
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Subclonal evolution of a classical Hodgkin lymphoma from a germinal center B-cell-derived mantle cell lymphomaIn: International Journal of Cancer Jg. 134 (2014) Nr. 4, S. 832 - 843Online Volltext: dx.doi.org/
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The PRDX2 gene is transcriptionally silenced and de novo methylated in Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphomaIn: Blood Jg. 123 (2014) Nr. 23, S. 3672 - 3674Online Volltext: dx.doi.org/
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B Cells in Chronically Hepatitis C Virus-Infected Individuals Lack a Virus-Induced Mutation Signature in the TP53, CTNNB1, and BCL6 GenesIn: Journal of Virology Jg. 87 (2013) Nr. 5, S. 2956 - 2962Online Volltext: dx.doi.org/
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Hodgkin-Reed-Sternberg cells in classical Hodgkin lymphoma show alterations of genes encoding the NADPH oxidase complex and impaired reactive oxygen species synthesis capacityIn: PLoS ONE Jg. 8 (2013) Nr. 12, S. e84928Online Volltext: dx.doi.org/ (Open Access)
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Incomplete cytokinesis and re-fusion of small mononucleated Hodgkin cells lead to giant multinucleated Reed-Sternberg cellsIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 110 (2013) Nr. 51, S. 20729 - 20734Online Volltext: dx.doi.org/
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Macrophages in T cell/histiocyte rich large B cell lymphoma strongly express metal-binding proteins and show a bi-activated phenotypeIn: International Journal of Cancer Jg. 133 (2013) Nr. 11, S. 2609 - 2618Online Volltext: dx.doi.org/
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Next generation transcriptome sequencing confirms the presence of somatic STAT3 mutations and identifies novel TNFAIP3 mutations in T Large Granular Lymphocytic Leukemia (T-LGL)In: Onkologie Jg. 36 (2013) Nr. Suppl. 7, S. 196
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Nodular lymphocyte predominant hodgkin lymphoma and T cell/histiocyte rich large B cell lymphoma : Endpoints of a spectrum of one disease?In: PLoS ONE Jg. 8 (2013) Nr. 11,Online Volltext: dx.doi.org/ (Open Access)
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Whole exome massive parallel sequencing of splenic marginal zone lymphoma reveals novel somatic mutations in NOTCH2 and SMYD1 genesIn: European Journal of Cancer (EJC) Jg. 49 (2013) Nr. Suppl. 2, S. 837
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Analyzing primary Hodgkin and Reed-Sternberg cells to capture the molecular and cellular pathogenesis of classical Hodgkin lymphomaIn: Blood Jg. 120 (2012) Nr. 23, S. 4609 - 4620Online Volltext: dx.doi.org/
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Array-based DNA methylation analysis in classical Hodgkin lymphoma reveals new insights into the mechanisms underlying silencing of B cell-specific genesIn: Leukemia Jg. 26 (2012) Nr. 1, S. 185 - 188Online Volltext: dx.doi.org/
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BLUEPRINT to decode the epigenetic signature written in bloodIn: Nature Biotechnology Jg. 30 (2012) Nr. 3, S. 224 - 226Online Volltext: dx.doi.org/
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Combined SNP Microarray Based Genomic Mapping and Next Generation Transcriptome Sequencing Confirms the Presence of Somatic STAT3 Mutations and Identifies Novel Chromosomal Imbalances and Candidate Genes in T Large Granular Lymphocytic Leukemia (T-LGL)In: Blood Jg. 120 (2012) Nr. 21, S. 3512Online Volltext: dx.doi.org/
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Differential Protein Stability and ALK Inhibitor Sensitivity of EML4-ALK Fusion VariantsIn: Clinical Cancer Research Jg. 18 (2012) Nr. 17, S. 4682 - 4690Online Volltext: dx.doi.org/ (Open Access)
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Genetic lesions of the TRAF3 and MAP3K14 genes in classical Hodgkin lymphomaIn: British Journal of Haematology Jg. 157 (2012) Nr. 6, S. 702 - 708Online Volltext: dx.doi.org/ (Open Access)
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Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adultsIn: Blood Jg. 118 (2011) Nr. 1, S. 139 - 147Online Volltext: dx.doi.org/
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MYC translocation architecture in B-NHLIn: Blood Jg. 144 (2024) Nr. 5, S. 469 - 471Online Volltext: dx.doi.org/
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Hodgkin lymphomaIn: The Journal of Clinical Investigation (JCI) Jg. 122 (2012) Nr. 10, S. 3439 - 3447Online Volltext: dx.doi.org/
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Elucidating the Enigmatic Pathobiology of Hodgin LymphomaIn: Hematological Oncology Jg. 41 (2023) Nr. S2, Supplement: 17th International Conference on Malignant Lymphoma, Palazzo dei Congressi, Lugano, Switzerland, 13 ‐ 17 June, 2023, S. 30Online Volltext: dx.doi.org/ (Open Access)
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Molecular Mechanisms in the Pathogenesis of Composite Lymphomas
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Genomic Analysis of Hodgkin Lymphoma
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IG‐MYC ‐positive leukemia and lymphoma with precursor B‐cell phenotype are genetically and epigenetically distinct from Burkitt lymphomas
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Low NR4A1 expression is associated with an up-regulation of immune checkpoints and their ligands in DLBCL
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Modeling of the Epigenome of the Cell-of-Origin Identifies Cancer-Specific DNA Methylation Patterns in CLL
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Reduced NR4A1 levels are associated with high expression of miR-15a and miR-15a*in DLBCL
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The DNA-methylation status of BCL11B in T-Cell-Large Granular Lymphocytic Leukemia - a diagnostic target
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Translation initiation factors are over-expressed in aggressive lymphomas and influence their clinical course
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CD30+ Germinal Center (GC) B cells are transciptionally related to light zone GC B cells reentering the dark zone, and to tumor cells of Classical Hodkin Lymphoma (CHL)In: Haematologica / The Hematology Journal Jg. 102 (2017) Nr. Suppl. 3, S. 30
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CDK9 Inhibition with LDC526 Is an Effective Treatment for T-Cell Prolymphocytic Leukemia (T-PLL) in VitroIn: Blood Jg. 130 (2017) Nr. Suppl. 1, S. 1262Online Volltext: dx.doi.org/
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Epigenetic analyses of T-cell large granular lymphocytic leukemia identify differentially methylated enhancer regions leading to deregulation of gene interactionsIn: Oncology Research and Treatment Jg. 40 (2017) Nr. Suppl. 3, Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, Stuttgart, 29. September-3. Oktober 2017: Abstracts, S. 109 - 110Online Volltext: dx.doi.org/
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Efficient chip architectures for a microfluidic cell sorter actuated by electrowetting and its electro-hydrodynamic analysisIn: 1st YRA MedTech Symposium 2016: April 8th / 2016 / University of Duisburg-Essen / 1st YRA MedTech Symposium (YRA-MedTech 2016), April 8th 2016 University of Duisburg-Essen, Duisburg, Germany / Erni, Daniel (Hrsg.) (2016) S. 31 - 32Online Volltext (Open Access)
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Genomic profiling of T-cell Prolymphocytic Leukemia (T-PLL) identifies novel recurrent mutations in SAMHD1 and PTPRC
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The AP-1 transcription factor BATF3 regulates MYC expression and is required for tumor cell survival in classical Hodgkin lymphoma and anaplastic large cell lymphomaIn: Haematologica / The Hematology Journal Jg. 101 (2016) Nr. S 5: You have access 10th International Symposium on Hodgkin Lymphoma, Cologne, Germany, October 22–25, 2016, Abstract Book, S. 2(Open Access)
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Cellular origin of CLL
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Moraxella Catarrhalis-A bacterial involvement in the origin of nodular lymphocyte predominant Hodgkin Lymphoma of IGD type?In: Haematologica / The Hematology Journal Jg. 100 (2015) Nr. Suppl.1, S. 106 - 107(Open Access)
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Moraxella catarrhalis - the infectious origin of nodular lymphocyte predominant Hodgkin lymphoma of IgD type?
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Aspects of Hodgkin lymphoma pathogenesis
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Autoreactivity of B cell receptors of nodular lymphocyte predominant Hodgkin lymphoma
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A Multimodal Single Cell Atlas of Human Tonsils Reveals New Insights into T and B Cell Differentiation
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