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Prof. Dr. phil. nat. George Iliakis

Telefon
K 41 52/41 53
E-Mail
Georg.Iliakis@uk-essen.de
Webseite
http://www.uni-due.de/zmb/members/iliakis/overview.shtml

Funktionen

  • Geschäftsführende/r Direktor/in, Institut für Medizinische Strahlenbiologie

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Lin, Xixi; Soni, Aashish; Hessenow, Razan; Sun, Yanjie; Mladenov, Emil; Guberina, Maja; Stuschke, Martin; Iliakis, George
    Talazoparib enhances resection at DSBs and renders HR-proficient cancer cells susceptible to Polθ inhibition
    In: Radiotherapy and Oncology (The Green Journal) Jg. 200 (2024) 110475
    Online Volltext: dx.doi.org/ (Open Access)
  • Dueva, Rositsa; Krieger, Lisa Marie; Li, Fanghua; Luo, Daxian; Xiao, Huaping; Stuschke, Martin; Metzen, Eric; Iliakis, George
    Chemical Inhibition of RPA by HAMNO Alters Cell Cycle Dynamics by Impeding DNA Replication and G2-to-M Transition but Has Little Effect on the Radiation-Induced DNA Damage Response
    In: International Journal of Molecular Sciences (IJMS) Jg. 24 (2023) Nr. 19, 14941
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Haberland, Vivien M. M.; Magin, Simon; Iliakis, George; Hartwig, Andrea
    Impact of Manganese and Chromate on Specific DNA Double-Strand Break Repair Pathways
    In: International Journal of Molecular Sciences (IJMS) Jg. 24 (2023) Nr. 12, 10392
    Online Volltext: dx.doi.org/ (Open Access)
  • Li, Fanghua; Mladenov, Emil; Sun, Yanjie; Soni, Aashish; Stuschke, Martin; Timmermann, Beate; Iliakis, George
    Low CDK Activity and Enhanced Degradation by APC/CCDH¹ Abolishes CtIP Activity and Alt-EJ in Quiescent Cells
    In: Cells Jg. 12 (2023) Nr. 11, 1530
    Online Volltext: dx.doi.org/ (Open Access)
  • Mladenov, Emil; Mladenova, Veronika; Stuschke, Martin; Iliakis, George
    New Facets of DNA Double Strand Break Repair : Radiation Dose as Key Determinant of HR versus c-NHEJ Engagement
    In: International Journal of Molecular Sciences (IJMS) Jg. 24 (2023) Nr. 19, 14956
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Luo, Daxian; Mladenov, Emil; Soni, Aashish; Stuschke, Martin; Iliakis, George
    The p38/MK2 Pathway Functions as Chk1-Backup Downstream of ATM/ATR in G₂-Checkpoint Activation in Cells Exposed to Ionizing Radiation
    In: Cells Jg. 12 (2023) Nr. 10, 1387
    Online Volltext: dx.doi.org/ (Open Access)
  • Soni, Aashish; Duan, Xiaolu; Stuschke, Martin; Iliakis, George
    ATR Contributes More Than ATM in Intra-S-Phase Checkpoint Activation after IR, and DNA-PKcs Facilitates Recovery : Evidence for Modular Integration of ATM/ATR/DNA-PKcs Functions
    In: International Journal of Molecular Sciences (IJMS) Jg. 23 (2022) Nr. 14, 7506
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Soni, Aashish; Lin, Xixi; Mladenov, Emil; Mladenova, Veronika; Stuschke, Martin; Iliakis, George
    BMN673 Is a PARP Inhibitor with Unique Radiosensitizing Properties: : Mechanisms and Potential in Radiation Therapy
    In: Cancers Jg. 14 (2022) Nr. 22, 5619
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Tremi, Ioanna; Havaki, Sophia; Georgitsopoulou, Sofia; Terzoudi, Georgia; Lykakis, Ioannis N.; Iliakis, George; Georgakilas, Vasilios; Gorgoulis, Vassilis G.; Georgakilas, Alexandros G.
    Biological Response of Human Cancer Cells to Ionizing Radiation in Combination with Gold Nanoparticles
    In: Cancers Jg. 14 (2022) Nr. 20, 5086
    Online Volltext: dx.doi.org/ (Open Access)
  • Mladenova, Veronika; Mladenov, Emil; Stuschke, Martin; Iliakis, George
    DNA Damage Clustering after Ionizing Radiation and Consequences in the Processing of Chromatin Breaks
    In: Molecules: A Journal of Synthetic Chemistry and Natural Product Chemistry Jg. 27 (2022) Nr. 5, 1540
    Online Volltext: dx.doi.org/ (Open Access)
  • Hamidi, Akram; Wolf, Alexandra; Dueva, Rositsa; Kaufmann, Melanie; Göpelt, Kirsten; Iliakis, George; Metzen, Eric
    Depletion of HIF-1α by Inducible Cre/loxP Increases the Sensitivity of Cultured Murine Hepatocytes to Ionizing Radiation in Hypoxia
    In: Cells Jg. 11 (2022) Nr. 10, 1671
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Khozooei, Shayan; Lettau, Konstanze; Barletta, Francesca; Jost, Tina; Rebholz, Simone; Veerappan, Soundaram; Franz-Wachtel, Mirita; Macek, Boris; Iliakis, George; Distel, Luitpold V.; Zips, Daniel; Toulany, Mahmoud
    Fisetin induces DNA double-strand break and interferes with the repair of radiation-induced damage to radiosensitize triple negative breast cancer cells
    In: Journal of Experimental & Clinical Cancer Research Jg. 41 (2022) Nr. 1, 256
    Online Volltext: dx.doi.org/ (Open Access)
  • Mladenov, Emil; Paul-Konietzko, Katja; Mladenova, Veronika; Stuschke, Martin; Iliakis, George
    Increased Gene Targeting in Hyper-Recombinogenic LymphoBlastoid Cell Lines Leaves Unchanged DSB Processing by Homologous Recombination
    In: International Journal of Molecular Sciences (IJMS) Jg. 23 (2022) Nr. 16, 9180
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Xiao, Huaping; Li, Fanghua; Mladenov, Emil; Soni, Aashish; Mladenova, Veronika; Pan, Bing; Dueva, Rositsa; Stuschke, Martin; Timmermann, Beate; Iliakis, George
    Increased Resection at DSBs in G₂-Phase Is a Unique Phenotype Associated with DNA-PKcs Defects That Is Not Shared by Other Factors of c-NHEJ
    In: Cells Jg. 11 (2022) Nr. 13, 2099
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Pei, Xile; Mladenov, Emil; Soni, Aashish; Li, Fanghua; Stuschke, Martin; Iliakis, George
    PTEN Loss Enhances Error-Prone DSB Processing and Tumor Cell Radiosensitivity by Suppressing RAD51 Expression and Homologous Recombination
    In: International Journal of Molecular Sciences (IJMS) Jg. 23 (2022) Nr. 21, 12876
    Online Volltext: dx.doi.org/ (Open Access)
  • Xu, Shan; Sak, Ali; Niedermaier, Ben; Erol, Yasin Bahadir; Groneberg, Michael; Mladenov, Emil; Kang, MingWei; Iliakis, George; Stuschke, Martin
    Selective vulnerability of ARID1A deficient colon cancer cells to combined radiation and ATR-inhibitor therapy
    In: Frontiers in Oncology Jg. 12 (2022) 999626
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Li, Fanghua; Mladenov, Emil; Dueva, Rositsa; Stuschke, Martin; Timmermann, Beate; Iliakis, George
    Shift in g₁-checkpoint from atm-alone to a cooperative atm plus atr regulation with increasing dose of radiation
    In: Cells Jg. 11 (2022) Nr. 1, 63
    Online Volltext: dx.doi.org/ (Open Access)
  • Mladenova, Veronika; Mladenov, Emil; Chaudhary, Shipra; Stuschke, Martin; Iliakis, George
    The high toxicity of DSB-clusters modelling high-LET-DNA damage derives from inhibition of c-NHEJ and promotion of alt-EJ and SSA despite increases in HR
    In: Frontiers in Cell and Developmental Biology Jg. 10 (2022) 1016951
    Online Volltext: dx.doi.org/ (Open Access)
  • Ehlert, Jens; Piel, Matthieu; Boege, Fritz; Cerchez, Mirela; Haas, Rainer J.; Iliakis, George; Prasad, Rajendra; Willi, Oswald; Monzel, Cornelia
    An experimental platform for studying the radiation effects of laser accelerated protons on mammalian cells
    In: AIP Advances Jg. 11 (2021) Nr. 6, 065208
    Online Volltext: dx.doi.org/ (Open Access)
  • Murmann-Konda, Tamara; Soni, Aashish; Stuschke, Martin; Iliakis, George
    Analysis of chromatid-break-repair detects a homologous recombination to non-homologous end-joining switch with increasing load of DNA double-strand breaks
    In: Mutation Research / Genetic Toxicology and Environmental Mutagenesis Jg. 867 (2021) 503372
    Online Volltext: dx.doi.org/
  • Krieger, Lisa Marie; Mladenov, Emil; Soni, Aashish; Demond, Marilen; Stuschke, Martin; Iliakis, George
    Disruption of chromatin dynamics by hypotonic stress suppresses hr and shifts dsb processing to error-prone ssa
    In: International Journal of Molecular Sciences (IJMS) Jg. 22 (2021) Nr. 20, 10957
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Nikolakopoulou, Aggeliki; Soni, Aashish; Habibi, Martha; Karaiskos, Pantelis; Pantelias, Gabriel; Terzoudi, Georgia I.; Iliakis, George
    G2/M Checkpoint Abrogation With Selective Inhibitors Results in Increased Chromatid Breaks and Radiosensitization of 82-6 hTERT and RPE Human Cells
    In: Frontiers in Public Health Jg. 9 (2021) 675095
    Online Volltext: dx.doi.org/ (Open Access)
  • Liu, Qi; Palomero, Luis; Moore, Jade; Guix, Ines; Espín, Roderic; Aytés, Alvaro; Mao, Jian-Hua; Paulovich, Amanda G.; Whiteaker, Jeffrey R.; Ivey, Richard G.; Iliakis, George; Luo, Daxian; Chalmers, Anthony J.; Murnane, John; Pujana, Miquel Angel; Barcellos-Hoff, Mary Helen
    Loss of TGFB signaling increases alternative end-joining DNA repair that sensitizes to genotoxic therapies across cancer types
    In: Science Translational Medicine Jg. 13 (2021) Nr. 580, eabc4465
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Hassiepen, Christina; Soni, Aashish; Rudolf, Ines; Boron, Vivian; Oeck, Sebastian; Iliakis, George; Schramm, Alexander
    NTRK1/TrkA activation overrides the G₂ /M-checkpoint upon irradiation
    In: Cancers Jg. 13 (2021) Nr. 23, 6023
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Iliakis, George E.
    New players in the regulation of DNA-PK activity : Survivin joins the crowd
    In: Cancer Research Jg. 81 (2021) Nr. 9, S. 2270 - 2271
    Online Volltext: dx.doi.org/ (Open Access)
  • Magin, Simon; Meher, Prabodha Kumar; Iliakis, George
    Nucleoside Analogs Radiosensitize G0 Cells by Activating DNA End Resection and Alternative End-Joining
    In: Radiation Research Jg. 195 (2021) Nr. 5, S. 412 - 426
    Online Volltext: dx.doi.org/
  • Soni, Aashish; Mladenov, Emil; Iliakis, George
    Proficiency in homologous recombination repair is prerequisite for activation of G₂-checkpoint at low radiation doses
    In: DNA Repair Jg. 101 (2021) S. 103076
    Online Volltext: dx.doi.org/
  • Mladenova, Veronika; Mladenov, Emil; Scholz, Michael; Stuschke, Martin; Iliakis, George
    Strong shift to atr-dependent regulation of the g₂-checkpoint after exposure to high-let radiation
    In: Life Jg. 11 (2021) Nr. 6, 560
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Wang, Huichen; Perrault, Ange Ronel; Takeda, Yoshihiko; Qin, Wei; Wang, Hongyan; Iliakis, George
    Biochemical evidence for Ku-independent backup pathways of NHEJ
    In: Nucleic Acids Research Jg. 48 (2020) Nr. 9, S. 5200
    Online Volltext: dx.doi.org/ (Open Access)
  • Soni, Aashish; Murmann-Konda, Tamara; Siemann-Loekes, Maria; Pantelias, Gabriel E.; Iliakis, George
    Chromosome breaks generated by low doses of ionizing radiation in G₂-phase are processed exclusively by gene conversion
    In: DNA Repair Jg. 89 (2020) S. 102828
    Online Volltext: dx.doi.org/
  • Magin, Simon; Georgoulis, Anastasios; Papadimitriou, Konstantinos; Iliakis, George; Vorgias, Constantinos E.
    Complete Genome Sequence of the Deep-Sea Bacterium Moritella marina MP-1 (ATCC 15381)
    In: Microbiology Resource Announcements Jg. 9 (2020) Nr. 4, S. e01321 - 19
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Wang, Xiang; Guan, Jun; Hu, Baocheng; Weiss, Robert S.; Iliakis, George; Wang, Ya
    Involvement of Hus1 in the chain elongation step of DNA replication after exposure to camptothecin or ionizing radiation
    In: Nucleic Acids Research Jg. 48 (2020) Nr. 6, S. 3396
    Online Volltext: dx.doi.org/ (Open Access)
  • Li, Fanghua; Mladenov, Emil; Mortoga, Sharif; Iliakis, George
    SCFSKP² regulates APC/CCDH¹-mediated degradation of CTIP to adjust DNA-end resection in G₂-phase
    In: Cell Death and Disease Jg. 11 (2020) Nr. 7, 548
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Mladenov, Emil; Staudt, Christian; Soni, Aashish; Murmann-Konda, Tamara; Siemann-Loekes, Maria; Iliakis, George
    Strong suppression of gene conversion with increasing DNA double-strand break load delimited by 53BP1 and RAD52
    In: Nucleic Acids Research Jg. 48 (2020) Nr. 4, S. 1905 - 1924
    Online Volltext: dx.doi.org/ (Open Access)
  • Soni, Aashish; Murmann-Konda, Tamara; Magin, Simon; Iliakis, George
    A method for the cell-cycle-specific analysis of radiation-induced chromosome aberrations and breaks
    In: Mutation Research / Fundamental and Molecular Mechanisms of Mutagenesis Jg. 815 (2019) S. 10 - 19
    Online Volltext: dx.doi.org/
  • Mladenov, Emil; Fan, Xiaoxiang; Paul-Konietzko, Katja; Soni, Aashish; Iliakis, George
    DNA-PKcs and ATM epistatically suppress DNA end resection and hyperactivation of ATR-dependent G₂-checkpoint in S-phase irradiated cells
    In: Scientific Reports Jg. 9 (2019) S. 14597
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Iliakis, George; Mladenova, Veronika; Sharif, Mortoga; Chaudhary, Shipra; Mavragani, Ifigeneia V.; Soni, Aashish; Saha, Janapriya; Schipler, Agnes; Mladenov, Emil
    Defined biological models of high-let radiation lesions
    In: Radiation Protection Dosimetry Jg. 183 (2019) Nr. 1-2, S. 60 - 68
    Online Volltext: dx.doi.org/
  • Iliakis, George; Mladenov, Emil; Mladenova, Veronika
    Necessities in the processing of DNA double strand breaks and their effects on genomic instability and cancer
    In: Cancers Jg. 11 (2019) Nr. 11, S. 1671
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Mladenov, Emil; Fan, Xiaoxiang; Dueva, Rositsa; Soni, Aashish; Iliakis, George
    Radiation-dose-dependent functional synergisms between ATM, ATR and DNA-PKcs in checkpoint control and resection in G₂-phase
    In: Scientific Reports Jg. 9 (2019) S. 8255
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Vaidya, Mithila; Jentsch, Julian A.; Peters, Susann; Keul, Petra; Weske, Sarah; Gräler, Markus H.; Mladenov, Emil; Iliakis, George; Heusch, Gerd; Levkau, Bodo
    Regulation of ABCA1-mediated cholesterol efflux by sphingosine-1-phosphate signaling in macrophages
    In: Journal of Lipid Research Jg. 60 (2019) Nr. 3, S. 506 - 515
    Online Volltext: dx.doi.org/ (Open Access)
  • Richter, Christin; Marquardt, Stephan; Li, Fanghua; Spitschak, Alf; Murr, Nico; Edelhäuser, Berdien A. H.; Iliakis, George; Pützer, Brigitte M.; Logotheti, Stella
    Rewiring E2F1 with classical NHEJ via APLF suppression promotes bladder cancer invasiveness
    In: Journal of Experimental & Clinical Cancer Research Jg. 38 (2019) Nr. 1, 292
    Online Volltext: dx.doi.org/ (Open Access)
  • Suntharalingam, Saravanabavaan; Mladenov, Emil; Sarabhai, Theresia; Wetter, Axel; Kraff, Oliver; Quick, Harald H.; Forsting, Michael; Iliakis, George; Naßenstein, Kai
    Abdominopelvic 1.5-T and 3.0-T MR imaging in healthy volunteers : Relationship to formation of DNA double-Strand breaks
    In: Radiology Jg. 288 (2018) Nr. 2, S. 529 - 535
    Online Volltext: dx.doi.org/ (Open Access)
  • Soni, Aashish; Li, Fanghua; Wang, You; Grabos, Martha; Krieger, Lisa Marie; Chaudhary, Shipra; Hasan, Mohammad Sharif Mortoga; Ahmed, Mansoor; Coleman, C Norman; Teicher, Beverly A.; Piekarz, Richard L.; Wang, Dian; Iliakis, George
    Inhibition of Parp1 by BMN673 Effectively Sensitizes Cells to Radiotherapy by Upsetting the Balance of Repair Pathways Processing DNA Double-Strand Breaks
    In: Molecular Cancer Therapeutics Jg. 17 (2018) Nr. 10, S. 2206 - 2216
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Mladenov, Emil; Li, Fanghua; Zhang, Lihua; Klammer, Holger; Iliakis, George
    Intercellular communication of DNA damage and oxidative status underpin bystander effects
    In: International Journal of Radiation Biology (RAB) Jg. 94 (2018) Nr. 8, S. 719 - 726
    Online Volltext: dx.doi.org/
  • Oeck, Sebastian; Szymonowicz, Klaudia; Wiel, Gesa; Krysztofiak, Adam; Lambert, Jamil; Koska, Benjamin; Iliakis, George; Timmermann, Beate; Jendrossek, Verena
    Relating Linear Energy Transfer to the Formation and Resolution of DNA Repair Foci After Irradiation with Equal Doses of X-ray Photons, Plateau, or Bragg-Peak Protons
    In: International Journal of Molecular Sciences (IJMS) Jg. 19 (2018) Nr. 12, S. 3779
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Szymonowicz, Klaudia; Oeck, Sebastian; Krysztofiak, Adam; van der Linden, Jansje; Iliakis, George; Jendrossek, Verena
    Restraining Akt1 Phosphorylation Attenuates the Repair of Radiation-Induced DNA Double-Strand Breaks and Reduces the Survival of Irradiated Cancer Cells
    In: International Journal of Molecular Sciences (IJMS) Jg. 19 (2018) Nr. 8, S. 2233
    Online Volltext: dx.doi.org/ (Open Access)
  • Pompsch, Mosche; Vogel, Julia; Classen, Fabian; Kranz, Philip; Iliakis, George; Riffkin, Helena; Brockmeier, Ulf; Metzen, Eric
    The presumed MTH1-inhibitor TH588 sensitizes colorectal carcinoma cells to ionizing radiation in hypoxia.
    In: BMC Cancer Jg. 18 (2018) S. 1190
    Online Volltext: dx.doi.org/ (Open Access)
  • Mothersill, Carmel; Abend, Michael; Bréchignac, François; Iliakis, George; Impens, Nathalie; Kadhim, Munira; Møller, Anders Pape; Oughton, Deborah; Powathil, Gibin; Saenen, Eline; Seymour, Colin; Sutcliffe, Jill; Tang, Fen-Ru; Schofield, Paul N.
    When a duck is not a duck : a new interdisciplinary synthesis for environmental radiation protection
    In: Environmental Research Jg. 162 (2018) S. 318 - 324
    Online Volltext: dx.doi.org/ (Open Access)
  • Oeck, S.; Al-Refae, K.; Riffkin, H.; Wiel, G.; Handrick, R.; Klein, Diana; Iliakis, George; Jendrossek, Verena
    Activating Akt1 mutations alter DNA double strand break repair and radiosensitivity
    In: Scientific Reports Jg. 7 (2017) S. 42700
    Online Volltext: dx.doi.org/ (Open Access)
  • Wieczorek, Sarah A.; Breitenbücher, Frank; Soni, Aashish; Paul-Konietzko, Katja; Ziegler, Sophie; Sak, Ali; Iliakis, George; Schuler, Martin
    Deregulated BCL-2 family proteins impact on repair of DNA double-strand breaks and are targets to overcome radioresistance in lung cancer
    In: Journal of Cancer Research and Clinical Oncology Jg. 143 (2017) Nr. 9, S. 1733 - 1744
    Online Volltext: dx.doi.org/
  • Krieger, Lisa Marie; Iliakis, George
    Wenn Stränge reißen : Wege der DNA-Doppelstrangbruch-Reparatur
    In: Biospektrum Jg. 23 (2017) Nr. 5, S. 502 - 505
    Online Volltext: dx.doi.org/
  • Schipler, Agnes; Mladenova, Veronika; Soni, Aashish; Nikolov, Vladimir; Saha, Janapriya; Mladenov, Emil; Iliakis, George
    Chromosome thripsis by DNA double strand break clusters causes enhanced cell lethality, chromosomal translocations and 53BP1-recruitment
    In: Nucleic Acids Research Jg. 44 (2016) Nr. 16, S. 7673 - 7690
    Online Volltext: dx.doi.org/ (Open Access)
  • Mladenov, Emil; Magin, Simon; Soni, Aashish; Iliakis, George
    DNA double-strand-break repair in higher eukaryotes and its role in genomic instability and cancer : Cell cycle and proliferation-dependent regulation
    In: Seminars in Cancer Biology Jg. 37-38 (2016) S. 51 - 64
    Online Volltext: dx.doi.org/
  • Nikitaki, Zacharenia; Nikolov, Vladimir; Mavragani, Ifigeneia V; Mladenov, Emil; Mangelis, Anastasios; Laskaratou, Danae A; Fragkoulis, Georgios I; Hellweg, Christine E; Martin, Olga A; Emfietzoglou, Dimitris; Hatzi, Vasiliki I; Terzoudi, Georgia I; Iliakis, George; Georgakilas, Alexandros G
    Measurement of complex DNA damage induction and repair in human cellular systems after exposure to ionizing radiations of varying linear energy transfer (LET)
    In: Free Radical Research Jg. 50 (2016) Nr. Suppl. 1, S. S64 - S78
    Online Volltext: dx.doi.org/ (Open Access)
  • Nikitaki, Z.; Nikolov, V.; Mavragani, I. V.; Plante, I.; Emfietzoglou, D.; Iliakis, George; Georgakilas, A. G.
    Non-DSB clustered DNA lesions. Does theory colocalize with the experiment?
    In: Radiation Physics and Chemistry Jg. 128 (2016) S. 26 - 35
    Online Volltext: dx.doi.org/
  • Mladenova, Veronika; Mladenov, Emil; Iliakis, George
    Novel Biological Approaches for Testing the Contributions of Single DSBs and DSB Clusters to the Biological Effects of High LET Radiation
    In: Frontiers in Oncology Jg. 6 (2016) S. 163
    Online Volltext: dx.doi.org/
  • Raschke, S; Spickermann, S; Toncian, T; Swantusch, M; Boeker, J; Giesen, U; Iliakis, George; Willi, O; Boege, F
    Ultra-short laser-accelerated proton pulses have similar DNA-damaging effectiveness but produce less immediate nitroxidative stress than conventional proton beams
    In: Scientific Reports Jg. 6 (2016) S. 32441
    Online Volltext: dx.doi.org/ (Open Access)
  • van den Boom, Johannes; Wolf, Markus; Weimann, Lena; Schulze, Nina; Li, Fanghua; Kaschani, Farnusch; Riemer, Anne; Zierhut, Christian; Kaiser, Markus; Iliakis, George; Funabiki, Hironori; Meyer, Hemmo
    VCP/p97 Extracts Sterically Trapped Ku70/80 Rings from DNA in Double-Strand Break Repair
    In: Molecular Cell Jg. 64 (2016) Nr. 1, S. 189 - 198
    Online Volltext: dx.doi.org/ (Open Access)
  • Iliakis, George; Murmann, Tamara; Soni, Aashish
    Alternative end-joining repair pathways are the ultimate backup for abrogated classical non-homologous end-joining and homologous recombination repair : Implications for the formation of chromosome translocations
    In: Mutation Research / Genetic Toxicology and Environmental Mutagenesis Jg. 793 (2015) S. 166 - 175
    Online Volltext: dx.doi.org/
  • Arakawa, Hiroshi; Iliakis, George
    Alternative okazaki fragment ligation pathway by dna ligase III
    In: Genes Jg. 6 (2015) Nr. 2, S. 385 - 398
    Online Volltext: dx.doi.org/ (Open Access)
  • Iliakis, George; Magin, Simon
    Balance shift between error-free and error prone DNA double-strand break repair as a novel mechanism of radiosensitization by nucleoside analogs
    In: Cancer Research Jg. 75 (2015) Nr. Suppl. 15, S. 3629
    Online Volltext: dx.doi.org/
  • Klammer, Holger; Mladenov, Emil; Li, Fanghua; Iliakis, George
    Bystander effects as manifestation of intercellular communication of DNA damage and of the cellular oxidative status
    In: Cancer Letters Jg. 356 (2015) Nr. 1, S. 58 - 71
    Online Volltext: dx.doi.org/
  • Paul-Konietzko, Katja; Thomale, Jürgen; Arakawa, Hiroshi; Iliakis, George
    DNA Ligases I and III Support Nucleotide Excision Repair in DT40 Cells with Similar Efficiency
    In: Photochemistry and Photobiology Jg. 91 (2015) Nr. 5, S. 1173 - 1180
    Online Volltext: dx.doi.org/
  • Magin, Simon; Papaioannou, Maria; Saha, Janapriya; Staudt, Christian; Iliakis, George
    Inhibition of homologous recombination and promotion of mutagenic repair of DNA double-strand breaks underpins arabinoside-nucleoside analogue radiosensitization
    In: Molecular Cancer Therapeutics Jg. 14 (2015) Nr. 6, S. 1424 - 1433
    Online Volltext: dx.doi.org/ (Open Access)
  • Soni, Aashish; Iliakis, George; Pantelias, Gabriel E.; Siemann, Maria
    Marked contribution of alternative end-joining to chromosome-translocation-formation by stochastically induced DNA double-strand-breaks in G2-phase human cells
    In: Mutation Research / Genetic Toxicology and Environmental Mutagenesis Jg. 793 (2015) S. 2 - 8
    Online Volltext: dx.doi.org/
  • Moscariello, Mario; Wieloch, Radi; Kurosawa, Aya; Li, Fanghua; Adachi, Noritaka; Mladenov, Emil; Iliakis, George
    Role for Artemis nuclease in the repair of radiation-induced DNA double strand breaks by alternative end joining
    In: DNA Repair Jg. 31 (2015) S. 29 - 40
    Online Volltext: dx.doi.org/
  • Li, Fanghua; Cheng, Yanlei; Iliakis, George
    The contribution of thermally labile sugar lesions to DNA double-strand break formation in cells grown in the presence of BrdU
    In: International Journal of Radiation Biology (RAB) Jg. 91 (2015) Nr. 4, S. 312 - 320
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  • Cheng, Yanlei; Li, Fanghua; Mladenov, Emil; Iliakis, George
    The yield of DNA double strand breaks determined after exclusion of those forming from heat-labile lesions predicts tumor cell radiosensitivity to killing
    In: Radiotherapy and Oncology (The Green Journal) Jg. 116 (2015) Nr. 3, S. 366 - 373
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  • Costantino, L.; Sotiriou, S. K.; Rantala, J. K.; Magin, S.; Mladenov, E.; Helleday, T.; Haber, J. E.; Iliakis, George; Kallioniemi, O. P.; Halazonetis, T. D.
    Break-induced replication repair of damaged forks induces genomic duplications in human cells
    In: Science Jg. 343 (2014) Nr. 6166, S. 88 - 91
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  • Soni, Aashish; Siemann, Maria; Grabos, Martha; Murmann, Tamara; Pantelias, Gabriel E; Iliakis, George
    Requirement for Parp-1 and DNA ligases 1 or 3 but not of Xrcc1 in chromosomal translocation formation by backup end joining
    In: Nucleic Acids Research Jg. 42 (2014) Nr. 10, S. 6380 - 6392
    Online Volltext: dx.doi.org/ (Open Access)
  • Dressler, A.; Riemer, Anne; Dobrynin, Grzegorz; Bremer, Sebastian; Soni, A.; Iliakis, George; Meyer, Hemmo
    The p97-Ufd1-Npl4 ATPase complex ensures robustness of the G2/M checkpoint by facilitating CDC25A degradation
    In: The FEBS Journal Jg. 281 (2014) Nr. Suppl. 1, S. 82
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  • Riemer, Anne; Dobrynin, Grzegorz; Dressler, Alina; Bremer, Sebastian; Soni, Aashish; Iliakis, George; Meyer, Hemmo
    The p97-Ufd1-Npl4 ATPase complex ensures robustness of the G2/M checkpoint by facilitating CDC25A degradation
    In: Cell Cycle Jg. 13 (2014) Nr. 6, S. 919 - 927
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  • Dueva, Rositsa; Iliakis, George
    Alternative pathways of non-homologous end joining (NHEJ) in genomic instability and cancer
    In: Translational Cancer Research Jg. 2 (2013) Nr. 3, S. 163 - 177
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  • Paul, Katja; Wang, Minli; Mladenov, Emil; Bencsik-Theilen, Alena; Bednar, Theresa; Wu, Wenqi; Arakawa, Hiroshi; Iliakis, George
    DNA Ligases I and III Cooperate in Alternative Non-Homologous End-Joining in Vertebrates
    In: PLoS ONE Jg. 8 (2013) Nr. 3, S. e59505
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  • Mladenov, Emil; Magin, Simon; Soni, Aashish; Iliakis, George
    DNA double-strand break repair as determinant of cellular radiosensitivity to killing and target in radiation therapy
    In: Frontiers in Oncology Jg. 3 (2013) S. 113
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Schipler, Agnes; Iliakis, George
    DNA double-strand-break complexity levels and their possible contributions to the probability for error-prone processing and repair pathway choice
    In: Nucleic Acids Research Jg. 41 (2013) Nr. 16, S. 7589 - 7605
    Online Volltext: dx.doi.org/ (Open Access)
  • Moscariello, Mario; Iliakis, George
    Effects of chromatin decondensation on alternative NHEJ
    In: DNA Repair Jg. 12 (2013) Nr. 11, S. 972 - 981
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  • Wu, Wenqi; Kong, Zhenzhen; Duan, Xiaolu; Zhu, Hanliang; Li, Shujue; Zeng, Shaohua; Liang, Yeping; Iliakis, George; Gui, Zhiming; Yang, Dong
    Inhibition of PARP1 by small interfering RNA enhances docetaxel activity against human prostate cancer PC3 cells
    In: Biochemical and Biophysical Research Communications (BBRC) Jg. 442 (2013) Nr. 1-2, S. 127 - 132
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  • Magin, Simon; Saha, Janapriya; Wang, Minli; Mladenova, Veronika; Coym, Nadine; Iliakis, George
    Lipofection and nucleofection of substrate plasmid can generate widely different readings of DNA end-joining efficiency in different cell lines
    In: DNA Repair Jg. 12 (2013) Nr. 2, S. 148 - 160
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  • Singh, Satyendra K; Bencsik-Theilen, Alena; Mladenov, Emil; Jakob, Burkhard; Taucher-Scholz, Gisela; Iliakis, George
    Reduced contribution of thermally labile sugar lesions to DNA double strand break formation after exposure to heavy ions
    In: Radiation Oncology Jg. 8 (2013) Nr. 1, S. 77
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  • Honke, Nadine; Shaabani, Namir; Zhang, Dong-Er; Iliakis, George; Xu, Haifeng C.; Häussinger, Dieter; Recher, Mike; Löhning, Max; Lang, Philipp A.; Lang, Karl S.
    Usp18 driven enforced viral replication in dendritic cells contributes to break of immunological tolerance in autoimmune diabetes
    In: PLoS Pathogens Jg. 9 (2013) Nr. 10,
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  • Mothersill, Carmel; Antonelli, Francesca; Dahle, Jostein; Dini, Valentina; Hegyesi, Hargita; Iliakis, George; Kämäräinen, Kamy; Launonen, Virpi; Lumniczky, Katalin; Lyng, Fiona; Safrany, Géza; Salomaa, Sisko; Schilling-Tóth, Boglárka; Tabocchini, Antonella; Kadhim, Munira A.
    A laboratory inter-comparison of the importance of serum serotonin levels in the measurement of a range of radiation-induced bystander effects : Overview of study and results presentation
    In: International Journal of Radiation Biology (RAB) Jg. 88 (2012) Nr. 10, S. 763 - 769
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  • Stankova, Katia; Ivanova, Katia; Mladenov, Emil; Rosidi, Bustanur; Sharma, Aparna; Boteva, Rayna; Iliakis, George
    Conformational transitions of proteins engaged in DNA double-strand break repair, analysed by tryptophan fluorescence emission and FRET
    In: Biochemical Journal Jg. 443 (2012) Nr. 3, S. 701 - 709
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  • Klammer, Holger; Zhang, Lihua; Kadhim, Munira; Iliakis, George
    Dependence of adaptive response and its bystander transmission on the genetic background of tested cells
    In: International Journal of Radiation Biology (RAB) Jg. 88 (2012) Nr. 10, S. 720 - 726
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  • Arakawa, Hiroshi; Bednar, Theresa; Wang, Minli; Paul, Katja; Mladenov, Emil; Bencsik-Theilen, Alena A.; Iliakis, George
    Functional redundancy between DNA ligases i and III in DNA replication in vertebrate cells
    In: Nucleic Acids Research Jg. 40 (2012) Nr. 6, S. 2599 - 2610
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  • Singh, Satyendra K.; Bednar, Theresa; Zhang, Lihua; Wu, Wenqi; Mladenov, Emil; Iliakis, George
    Inhibition of B-NHEJ in plateau-phase cells is not a direct consequence of suppressed growth factor signaling
    In: International Journal of Radiation Oncology, Biology, Physics Jg. 84 (2012) Nr. 2, S. e237 - e243
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  • Manova, Vasilissa; Singh, Satyendra K.; Iliakis, George
    Processing of DNA double strand breaks by alternative non-homologous end-joining in hyperacetylated chromatin
    In: Genome Integrity Jg. 3 (2012) S. 4
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  • Singh, Satyendra K.; Wu, Wenqi; Stuschke, Martin; Bockisch, Andreas; Iliakis, George
    Reduced contribution of thermally-labile sugar lesions to DNA double-strand break formation after exposure to neutrons
    In: Radiation Research Jg. 178 (2012) Nr. 6, S. 581 - 590
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  • Aziz, K.; Nowsheen, S.; Pantelias, G.; Iliakis, George; Gorgoulis, V.G.; Georgakilas, A.G.
    Targeting DNA damage and repair : Embracing the pharmacological era for successful cancer therapy
    In: Pharmacology & Therapeutics Jg. 133 (2012) Nr. 3, S. 334 - 350
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  • Klammer, Holger; Iliakis, George
    The impact of serotonin on the development of bystander damage assessed by γ-H2AX foci analysis
    In: International Journal of Radiation Biology (RAB) Jg. 88 (2012) Nr. 10, S. 777 - 780
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  • Mladenov, Emil; Iliakis, George
    Induction and repair of DNA double strand breaks : The increasing spectrum of non-homologous end joining pathways
    In: Mutation Research / Fundamental and Molecular Mechanisms of Mutagenesis Jg. 711 (2011) Nr. 1-2, S. 61 - 72
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  • Singh, Satyendra K.; Wang, Minli; Staudt, Christian; Iliakis, George
    Post-irradiation chemical processing of DNA damage generates double-strand breaks in cells already engaged in repair
    In: Nucleic Acids Research Jg. 39 (2011) Nr. 19, S. 8416 - 8429
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  • Singh, Satyendra K.; Wu, Wenqi; Zhang, Lihua; Klammer, Holger; Wang, Minli; Iliakis, George
    Widespread dependence of backup NHEJ on growth state : Ramifications for the use of DNA-PK inhibitors
    In: International Journal of Radiation Oncology, Biology, Physics Jg. 79 (2011) Nr. 2, S. 540 - 548
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  • Klammer, Holger; Kadhim, Munira; Iliakis, George
    Evidence of an adaptive response targeting DNA nonhomologous end joining and its transmission to bystander cells
    In: Cancer Research Jg. 70 (2010) Nr. 21, S. 8498 - 8506
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  • Fan, Xiaoxiang; Cheong, Nge; Iliakis, George
    Initial characterization of a low-molecular-weight factor enhancing the checkpoint response
    In: Radiation Research Jg. 174 (2010) Nr. 4, S. 424 - 435
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  • Terzoudi, G.I.; Donta-Bakoyianni, C.; Iliakis, George; Pantelias, G.E.
    Investigation of bystander effects in hybrid cells by means of cell fusion and premature chromosome condensation induction
    In: Radiation Research Jg. 173 (2010) Nr. 6, S. 789 - 801
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  • Iliakis, George
    New partners for Chk1
    In: Cell Cycle Jg. 9 (2010) Nr. 11, S. 2061 - 2062
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  • Iliakis, George
    The anatomy and cell cycle evolution of DNA damage signaling and repair foci
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  • Iliakis, George
    Backup pathways of NHEJ in cells of higher eukaryotes : Cell cycle dependence
    In: Radiotherapy and Oncology (The Green Journal) Jg. 92 (2009) Nr. 3, S. 310 - 315
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  • Singh, Satyendra K.; Wu, Weizhong; Wu, Wenqi; Wang, Minli; Iliakis, George
    Extensive repair of DNA double-strand breaks in cells deficient in the DNA-PK-dependent pathway of NHEJ after exclusion of heat-labile sites
    In: Radiation Research Jg. 172 (2009) Nr. 2, S. 152 - 164
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  • Iliakis, George; Wu, Wenqi; Wang, Minli
    DNA double strand break repair inhibition as a cause of heat radiosensitization : Re-evaluation considering backup pathways of NHEJ
    In: International Journal of Hyperthermia Jg. 24 (2008) Nr. 1, S. 17 - 29
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  • Wu, Wenqi; Wang, Minli; Mussfeldt, Tamara; Iliakis, George
    Enhanced use of backup pathways of NHEJ in G₂ in Chinese hamster mutant cells with defects in the classical pathway of NHEJ
    In: Radiation Research Jg. 170 (2008) Nr. 4, S. 512 - 520
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  • Kinner, Andrea; Wu, Wenqi; Staudt, Christian; Iliakis, George
    Gamma-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin.
    In: Nucleic Acids Research Jg. 36 (2008) Nr. 17, S. 5678 - 5694
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  • Rosidi, Bustanur; Wang, Minli; Wu, Wenqi; Sharma, Aparna; Wang, Huichen; Iliakis, George
    Histone H1 functions as a stimulatory factor in backup pathways of NHEJ
    In: Nucleic Acids Research Jg. 36 (2008) Nr. 5, S. 1610 - 1623
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  • Terzoudi, Georgia I; Singh, Satyendra Kumar; Pantelias, Gabriel E; Iliakis, George
    Premature chromosome condensation reveals DNA-PK independent pathways of chromosome break repair
    In: International Journal of Oncology Jg. 33 (2008) Nr. 4, S. 871 - 879
  • Wu, Wenqi; Wang, Minli; Wu, Weizhong; Singh, Satyendra K.; Mussfeldt, Tamara; Iliakis, George
    Repair of radiation induced DNA double strand breaks by backup NHEJ is enhanced in G2
    In: DNA Repair Jg. 7 (2008) Nr. 2, S. 329 - 338
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  • Tamulevicius, Peter; Wang, Minli; Iliakis, George
    Homology-directed repair is required for the development of radioresistance during S phase : Interplay between double-strand break repair and checkpoint response
    In: Radiation Research Jg. 167 (2007) Nr. 1, S. 1 - 11
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  • Windhofer, Frank; Wu, Wenqi; Iliakis, George
    Low levels of DNA ligases III and IV sufficient for effective NHEJ
    In: Journal of Cellular Physiology Jg. 213 (2007) Nr. 2, S. 475 - 483
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  • Windhofer, Frank; Wu, Wenqi; Wang, Minli; Singh, Satyendra K.; Saha, Janapriya; Rosidi, Bustanur; Iliakis, George
    Marked Dependence on Growth State of Backup Pathways of NHEJ
    In: International Journal of Radiation Oncology, Biology, Physics Jg. 68 (2007) Nr. 5, S. 1462 - 1470
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  • Böcker, Wilfried; Iliakis, George
    Computational methods for analysis of foci : Validation for radiation-induced γ-H2AX foci in human cells
    In: Radiation Research Jg. 165 (2006) Nr. 1, S. 113 - 124
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  • Wang, Minli; Wu, Weizhong; Wu, Wenqi; Rosidi, Bustanur; Zhang, Lihua; Wang, Huichen; Iliakis, George
    PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways
    In: Nucleic Acids Research Jg. 34 (2006) Nr. 21, S. 6170 - 6182
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  • Banaz-Yaşar, Ferya; Tischka, Rabea; Iliakis, George; Winterhager, Elke; Gellhaus, Alexandra
    Cell line specific modulation of connexin43 expression after exposure to ionizing radiation
    In: Cell Communication and Adhesion Jg. 12 (2005) Nr. 5-6, S. 249 - 259
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  • Terzoudi, Georgia I.; Manola, Kaliopi N.; Pantelias, Gabriel E.; Iliakis, George
    Checkpoint abrogation in G₂ compromises repair of chromosomal breaks in ataxia telangiectasia cells
    In: Cancer Research Jg. 65 (2005) Nr. 24, S. 11292 - 11296
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  • Wang, Hongyan; Wang, Minli; Wang, Huichen; Böcker, Wilfried; Iliakis, George
    Complex H2AX phosphorylation patterns by multiple kinases including ATM and DNA-PK in human cells exposed to ionizing radiation and treated with kinase inhibitors
    In: Journal of Cellular Physiology Jg. 202 (2005) Nr. 2, S. 492 - 502
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  • Wang, Huichen; Rosidi, Bustanur; Perrault, Ronel; Wang, Minli; Zhang, Lihua; Windhofer, Frank; Iliakis, George
    DNA ligase III as a candidate component of backup pathways of nonhomologous end joining
    In: Cancer Research Jg. 65 (2005) Nr. 10, S. 4020 - 4030
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  • Wu, Wei-Zhong; Sun, Hui-Chuan; Shen, Yue-Fang; Chen, Jie; Wang, Lu; Tang, Zhao-You; Iliakis, George; Liu, Kang-Da
    Interferon alpha 2a downregulates VEGF expression through PI3 kinase and MAP kinase signaling pathways
    In: Journal of Cancer Research and Clinical Oncology Jg. 131 (2005) Nr. 3, S. 169 - 178
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  • Martín, Marta; Genescà, Anna; Latre, Laura; Jaco, Isabel; Taccioli, Guillermo E.; Egozcue, Josep; Blasco, María A.; Iliakis, George; Tusell, Laura
    Postreplicative joining of DNA double-strand breaks causes genomic instability in DNA-PKcs-deficient mouse embryonic fibroblasts
    In: Cancer Research Jg. 65 (2005) Nr. 22, S. 10223 - 10232
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  • Wang, Hongyan; Wang, Huichen; Powell, Simon N.; Iliakis, George; Wang, Ya
    ATR affecting cell radiosensitivity is dependent on homologous recombination repair but independent of nonhomologous end joining
    In: Cancer Research Jg. 64 (2004) Nr. 19, S. 7139 - 7143
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  • Perrault, Ronel; Wang, Huichen; Wang, Minli; Rosidi, Bustanur; Iliakis, George
    Backup pathways of NHEJ are suppressed by DNA-PK
    In: Journal of Cellular Biochemistry Jg. 92 (2004) Nr. 4, S. 781 - 794
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  • Wang, Huichen; Böcker, Wilfried; Wang, Hongyan; Wang, Xiang; Guan, Jun; Thompson, Larry H.; Nickoloff, Jac A.; Iliakis, George
    Caffeine inhibits homology-directed repair of I-SceI-induced DNA double-strand breaks
    In: Oncogene Jg. 23 (2004) Nr. 3, S. 824 - 834
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  • Iliakis, George; Krieg, T.; Guan, J.; Wang, Y.; Leeper, D.
    Evidence for an S-Phase checkpoint regulating DNA replication after heat shock : A review
    In: International Journal of Hyperthermia Jg. 20 (2004) Nr. 2, S. 240 - 249
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  • Iliakis, George; Wang, H.; Perrault, A.R.; Böcker, Wilfried; Rosidi, B.; Windhofer, F.; Wu, W.; Guan, J.; Terzoudi, G.; Panteliasc, G.; Pantelias, G.
    Mechanisms of DNA double strand break repair and chromosome aberration formation
    In: Cytogenetic and Genome Research Jg. 104 (2004) Nr. 1-4, S. 14 - 20
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  • Wang, Xiang; Khadpe, Jay; Hu, Baocheng; Iliakis, George; Wang, Ya
    An overactivated ATR/CHK1 pathway is responsible for the prolonged G ₂ accumulation in irradiated AT cells
    In: The Journal of Biological Chemistry (JBC) Jg. 278 (2003) Nr. 33, S. 30869 - 30874
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  • Wang, Huichen; Wang, Xiang; Iliakis, George; Wang, Ya
    Caffeine Could Not Efficiently Sensitize Homologous Recombination Repair-Deficient Cells to Ionizing Radiation-Induced Killing
    In: Radiation Research Jg. 159 (2003) Nr. 3, S. 420 - 425
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  • Wang, Xiang; Wang, Huichen; Iliakis, George; Wang, Ya
    Caffeine-Induced Radiosensitization is Independent of Nonhomologous End Joining of DNA Double-Strand Breaks
    In: Radiation Research Jg. 159 (2003) Nr. 3, S. 426 - 432
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  • Iliakis, George; Wang, Ya; Guan, Jun; Wang, Huichen
    DNA damage checkpoint control in cells exposed to ionizing radiation
    In: Oncogene Jg. 22 (2003) Nr. 37, S. 5834 - 5847
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  • Dicker, Adam P.; Williams, Torian L.; Iliakis, George; Grant, Derrick S.
    Targeting Angiogenic Processes by Combination Low-Dose Paclitaxel and Radiation Therapy
    In: American Journal of Clinical Oncology Jg. 26 (2003) Nr. 3, S. e45 - e53
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  • Sharma, Girdhar G.; Gupta, Arun; Wang, Huichen; Scherthan, Harry; Dhar, Sonu; Gandhi, Varsha; Iliakis, George; Shay, Jerry W.; Young, Charles S.H.; Pandita, Tej K.
    hTERT associates with human telomeres and enhances genomic stability and DNA repair
    In: Oncogene Jg. 22 (2003) Nr. 1, S. 131 - 146
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  • Zhou, Xiang-Yang; Wang, Xiang; Hu, Baocheng; Guan, Jun; Iliakis, George; Wang, Ya
    An ATM-independent S-phase checkpoint response involves CHK1 pathway
    In: Cancer Research Jg. 62 (2002) Nr. 6, S. 1598 - 1603
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  • Wang, Jia-Lun; Wang, Xiang; Wang, Hongyan; Iliakis, George; Wang, Ya
    CHK1-regulated S-phase checkpoint response reduces camptothecin cytotoxicity
    In: Cell Cycle Jg. 1 (2002) Nr. 4, S. 267 - 272
  • Zeng, Zhao-Chong; Jiang, Guo-Liang; Wang, Guo-Min; Tang, Zhao-You; Curran, Walter J.; Iliakis, George
    DNA-PKcs subunits in radiosensitization by hyperthermia on hepatocellular carcinoma hepG₂ cell line
    In: World Journal of Gastroenterology Jg. 8 (2002) Nr. 5, S. 797 - 803
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  • Guan, Jun; Stavridi, Elena; Leeper, Dennis B.; Iliakis, George
    Effects of hyperthermia on p53 protein expression and activity
    In: Journal of Cellular Physiology Jg. 190 (2002) Nr. 3, S. 365 - 374
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  • Zhou, Xiang-Yang; Wang, Xiang; Wang, Hongyan; Chen, David J.; Li, Gloria C.; Iliakis, George; Wang, Ya
    Ku affects the ATM-dependent S phase checkpoint following ionizing radiation
    In: Oncogene Jg. 21 (2002) Nr. 41, S. 6377 - 6381
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  • Wang, Xiang; Li, Gloria C; Iliakis, George; Wang, Ya
    Ku affects the CHK1-dependent G(2) checkpoint after ionizing radiation
    In: Cancer Research Jg. 62 (2002) Nr. 21, S. 6031 - 6034
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  • Wang, Hongyan; Wang, Xiang; Zhou, Xiang-Yang; Chen, David J; Li, Gloria C; Iliakis, George; Wang, Ya
    Ku affects the ataxia and Rad 3-related/CHK1-dependent S phase checkpoint response after camptothecin treatment.
    In: Cancer Research Jg. 62 (2002) Nr. 9, S. 2483 - 2487
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  • Xia, Fen; Taghian, Danielle G.; DeFrank, Jeffrey S.; Zeng, Zhao-Chong; Willers, Henning; Iliakis, George; Powell, Simon N.; Zeng, Z.-C.
    Deficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joining
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 98 (2001) Nr. 15, S. 8644 - 8649
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  • Wang, Huichen; Zeng, Zhao-Chong; Bui, Tu-Anh; Sonoda, Eiichiro; Takata, Minoru; Takeda, Shunichi; Iliakis, George
    Efficient rejoining of radiation-induced DNA double-strand breaks in vertebrate cells deficient in genes of the RAD52 epistasis group
    In: Oncogene Jg. 20 (2001) Nr. 18, S. 2212 - 2224
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  • Cheong, N; Zeng, Z C; Wang, Y; Iliakis, George
    Evidence for factors modulating radiation-induced G2-delay : potential application as radioprotectors.
    In: Physica Medica: European Journal of Medical Physics Jg. 17 (2001) Nr. Suppl. 1, S. 205 - 209
  • Wang, Huichen; Zeng, Zhao-Chong; Perrault, Ange R.; Cheng, Xinbo; Qin, Wei; Iliakis, George
    Genetic evidence for the involvement of DNA ligase IV in the DNA-PK-dependent pathway of non-homologous end joining in mammalian cells
    In: Nucleic Acids Research Jg. 29 (2001) Nr. 8, S. 1653 - 1660
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  • Peters, K B; Wang, H; Brown, J M; Iliakis, George
    Inhibition of DNA replication by tirapazamine
    In: Cancer Research Jg. 61 (2001) Nr. 14, S. 5425 - 5431
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  • Wang, H; Zeng, Z C; Bui, T A; DiBiase, S J; Qin, W; Xia, F; Powell, S N; Iliakis, George
    Nonhomologous end-joining of ionizing radiation-induced DNA double-stranded breaks in human tumor cells deficient in BRCA1 or BRCA2
    In: Cancer Research Jg. 61 (2001) Nr. 1, S. 270 - 277
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  • Perrault, R.; Cheong, Nge; Wang, Huichen; Wang, Hongyan; Iliakis, George
    RPA facilitates rejoining of DNA double-strand breaks in an in vitro assay utilizing genomic DNA as substrate
    In: International Journal of Radiation Biology (RAB) Jg. 77 (2001) Nr. 5, S. 593 - 607
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  • Wang, Yizheng; Guan, Jun; Wang, Hongyan; Wang, Ya; Leeper, Dennis; Iliakis, George
    Regulation of DNA Replication after Heat Shock by Replication Protein A-Nucleolin Interactions
    In: The Journal of Biological Chemistry (JBC) Jg. 276 (2001) Nr. 23, S. 20579 - 20588
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  • Wang, H; Guan, J; Perrault, A R; Wang, Y; Iliakis, George
    Replication protein A2 phosphorylation after DNA damage by the coordinated action of ataxia telangiectasia-mutated and DNA-dependent protein kinase
    In: Cancer Research Jg. 61 (2001) Nr. 23, S. 8554 - 8563
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  • Andrews, D.W.; Resnicoff, M.; Flanders, A.E.; Kenyon, L.; Curtis, M.; Merli, G.; Baserga, R.; Iliakis, George; Aiken, R.D.
    Results of a pilot study involving the use of an antisense oligodeoxynucleotide directed against the insulin-like growth factor type I receptor in malignant astrocytomas
    In: Journal of Clinical Oncology Jg. 19 (2001) Nr. 8, S. 2189 - 2200
    Online Volltext: dx.doi.org/
  • Hu, Baocheng; Zhou, Xiang-Yang; Wang, Xiang; Zeng, Zhao-Chong; Iliakis, George; Wang, Ya
    The Radioresistance to Killing of A1-5 Cells Derives from Activation of the Chk1 Pathway
    In: The Journal of Biological Chemistry (JBC) Jg. 276 (2001) Nr. 21, S. 17693 - 17698
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • DiBiase; Zeng; Chen; Hyslop; Curran; Iliakis, George
    DNA-dependent protein kinase stimulates an independently active, nonhomologous, end-joining apparatus.
    In: Cancer Research Jg. 60 (2000) Nr. 5, S. 1245 - 1253
    Online Volltext
  • Asaad, Nesrin A.; Zeng, Zhao-Chong; Guan, Jun; Thacker, John; Iliakis, George
    Homologous recombination as a potential target for caffeine radiosensitization in mammalian cells : Reduced caffeine radiosensitization in XRCC2 and XRCC3 mutants
    In: Oncogene Jg. 19 (2000) Nr. 50, S. 5788 - 5800
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Wachsberger, P.R.; Iliakis, George
    Hyperthermia does not affect rejoining of DNA double-strand breaks in a cell-free assay
    In: International Journal of Radiation Biology (RAB) Jg. 76 (2000) Nr. 3, S. 313 - 326
    Online Volltext: dx.doi.org/
  • Guan, Jun; DiBiase, Steven; Iliakis, George
    The catalytic subunit DNA-dependent protein kinase (DNA-PKcs) facilitates recovery from radiation-induced inhibition of DNA replication
    In: Nucleic Acids Research Jg. 28 (2000) Nr. 5, S. 1183 - 1192
    Online Volltext: dx.doi.org/ (Open Access)

    • Vorworte / Nachworte

  • Hamada, Nobuyuki; Mothersill, Carmel E.; Iliakis, George
    Preface to the IJRB 60th anniversary special issue “back to our future”
    In: International Journal of Radiation Biology (RAB) Jg. 95 (2019) Nr. 7, 60th Anniversary Special Issue: Back to our Future, S. 799 - 801
    Online Volltext: dx.doi.org/ (Open Access)

    • Abstracts

  • Qiu, Ye; Mladenov, Emil; Thomale, Jürgen; Sak, Ali; Stuschke, Martin; Iliakis, George
    Cell cycle specific analysis of cisplatin-radiation interactions : Focus on DNA double strand break induction and processing
    In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 199 (2023)
    Online Volltext: dx.doi.org/ (Open Access)
  • Hessenow, Razan; Behrends, Carina; Xixi, Lin; Mladenov, Emil; Matschke, Johann; Aashish, Soni; Stuschke, Martin; Iliakis, George; Jendrossek, Verena; Timmermann, Beate
    Defects in DNA Damage Response Reinforce Proton Beam Specific Radiosensitivity of Cancer Cells
    In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 199 (2023) Nr. Suppl. 1, S. S36 - S37
    Online Volltext: dx.doi.org/ (Open Access)
  • Yasin Bahadir, Erol; Sak, Ali; Groneberg, Michael; Thomale, Jürgen; Iliakis, George; Stuschke, Martin
    Effect of combined Cisplatin treatment and Mre11 inhibition on radiation induced DSB Repair in NSCLC cell lines and human fibroblast cells
    In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 199 (2023) Nr. Suppl. 1, S. S138
    Online Volltext: dx.doi.org/ (Open Access)
  • Mladenov, Emil; Staudt, Christian; Aashish, Soni; Mladenova, Veronika; Stuschke, Martin; Iliakis, George
    Enhanced engagement of homologous recombination repair at low doses of radiation provides rationale for dose fractionation in the clinic
    In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 199 (2023) Nr. Suppl. 1, S. S135
    Online Volltext: dx.doi.org/ (Open Access)
  • Mladenova, Veronika; Mladenov, Emil; Chaudhary, Shipra; Stuschke, Martin; Iliakis, George
    Rationale for increased implementation of high LET ionizing radiation in cancer therapy
    In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 199 (2023) Nr. Suppl. 1, S. S135 - S136
    Online Volltext: dx.doi.org/ (Open Access)
  • Lin, Xixi; Soni, Aashish; Hassenow, Razan; Stuschke, Martin; Iliakis, George
    Targeting Polθ robustly enhances radiosensitization by talazoparib in cancer cells
    In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 199 (2023) Nr. Suppl. 1, S. S135
    Online Volltext: dx.doi.org/ (Open Access)
  • Iliakis, George; Mladenov, E.; Mladenova, V.; Soni, A.; Stuschke, Martin; Scholz, M.
    DSB complexity : A key to cell lethality
    In: Radiotherapy and Oncology (The Green Journal) Jg. 170 (2022) Nr. Suppl. 1, S. 754 - S754
  • Perez, Lopez; Mladenov, E.; Mladenov, V.; Weber, K.-J.; Engelhardt, J.; Iliakis, George; Huber, P.E.
    On the Importance of Ultrastructural Organization of DNA Double Strand Break-Repair Foci
    In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 194 (2018) Nr. Suppl. 1, S. 27 - S28
    Online Volltext: dx.doi.org/; Online Volltext: dx.doi.org/ (Open Access)
  • Oeck, S.; Riffkin, H.; Madel, R.; Handrick, R.; Al-Refae, K.; Iliakis, George; Jendrossek, Verena
    The role of protein kinase B alpha (Akt1) in the cellular response to ionizing radiation
    In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 191 (2015) Nr. Suppl.1, S. S74 - S75
    Online Volltext: dx.doi.org/
  • Ontikatze, T.; Matschke, Johann; Grimm, F.; Brost, R.; Moscariello, M.; Iliakis, George; Jendrossek, Verena;
    Dihydroartemisinin exerts context-dependent lethal effects in combination with ionizing radiation
    19. Jahreskongress der Deutschen Gesellschaft für Radioonkologie; 9. bis 12. Mai 2013, Berlin,
    In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 189 (2013) Nr. SUPPL. 1, S. 128 - 129
    Online Volltext: dx.doi.org/

    • Beiträge in Sammelwerken und Tagungsbänden

  • Mladenov, Emil; Saha, Janapriya; Iliakis, George
    Processing-challenges generated by clusters of DNA double-strand breaks underpin increased effectiveness of high-LET radiation and chromothripsis
    In: Chromosome Translocation / Yu, Zhang (Hrsg.) 2018, S. 149 - 168
    Online Volltext: dx.doi.org/
  • Iliakis, George; Mladenov, Emil; Wang, Ya; Wang, Hong Yan
    Analysis of Inhibition of DNA Replication in Irradiated Cells Using the SV40 Based In Vitro Assay of DNA Replication
    In: DNA Repair Protocols / Bjergbæk, Lotte (Hrsg.) 2012, S. 591 - 602
    Online Volltext: dx.doi.org/
  • Iliakis, George; Mladenov, Emil; Cheong, Nge
    In vitro rejoining of double strand breaks in genomic DNA
    In: DNA Repair Protocols / Bjergbæk, Lotte (Hrsg.) 2012, S. 471 - 484
    Online Volltext: dx.doi.org/
  • Raschke, Sascha; Guan, Jun; Iliakis, George
    Application of alkaline sucrose gradient centrifugation in the analysis of DNA replication after DNA damage
    In: DNA Replication: Methods and Protocols / Vengrova, Sonya; Dalgaard, Jacob Z. (Hrsg.) 2009, S. 329 - 342
    Online Volltext: dx.doi.org/
  • Iliakis, George; Rosidi, Bustanur; Wang, Minli; Wang, Huichen
    Plasmid-based assays for DNA end-joining in vitro
    In: DNA Repair Protocols: Mammalian Systems / Henderson, Daryl S. (Hrsg.) 2006, S. 123 - 131
    Online Volltext: dx.doi.org/