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Institut für Medizinische Mikrobiologie am Universitätsklinikum Essen
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Hufelandstr. 55
45122 Essen
45122 Essen
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Universitätsprofessor/in, Institut für Medizinische Mikrobiologie
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Prorektorin, Rektorat
Prorektorin für Forschung und wissenschaftlichen Nachwuchs
AnschriftUniversitätsstr. 2, 45141 Essen
Postanschrift: Forsthausweg 2,LG502,47057 DuisburgRaumT01 S06 B34Telefon -
Beratendes Mitglied, Kommission für Forschung, wissenschaftlichen Nachwuchs und Wissenstransfer
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Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Direct effects of heroin and methadone on T cell functionIn: International Immunopharmacology Jg. 140 (2024) 112736Online Volltext: dx.doi.org/ (Open Access)
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Evaluation of a Multimodal Stress Management and Comprehensive Lifestyle Modification Program on Quality of Life and Gastrointestinal Symptoms in Patients with Crohn's Disease : A Randomized Controlled Pilot Trial with 9-Month Follow-UpIn: Digestion Jg. 105 (2024) Nr. 3, S. 201 - 212Online Volltext: dx.doi.org/
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Influenza virus infection enhances tumour-specific CD8+ T-cell immunity, facilitating tumour controlIn: PLoS Pathogens Jg. 20 (2024) Nr. 1, e1011982Online Volltext: dx.doi.org/ (Open Access)
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Lack of canonical thyroid hormone receptor α signaling changes regulatory T cell phenotype in female miceIn: iScience Jg. 27 (2024) Nr. 8, 110547Online Volltext: dx.doi.org/ (Open Access)
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Lifestyle Intervention Modulates the CD4+ T Cell Profile in the Blood of Crohn’s Disease PatientsIn: Inflammatory Bowel Diseases (2024) in pressOnline Volltext: dx.doi.org/
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The ST2⁺ Treg/amphiregulin axis protects from immune-mediated hepatitisIn: Frontiers in Immunology Jg. 15 (2024) 1351405Online Volltext: dx.doi.org/ (Open Access)
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Acute cytomegalovirus infection modulates the intestinal microbiota and targets intestinal epithelial cellsIn: European Journal of Immunology Jg. 53 (2023) Nr. 2, 2249940Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Barium sulphate microparticles are taken up by three different cell types: HeLa, THP-1, and hMSCIn: Acta Biomaterialia Jg. 164 (2023) S. 577 - 587Online Volltext: dx.doi.org/
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CD47 blockade enhances phagocytosis of cardiac cell debris by neutrophilsIn: International Journal of Cardiology (IJC) Heart & Vasculature Jg. 48 (2023) 101269Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Independent human mesenchymal stromal cell–derived extracellular vesicle preparations differentially attenuate symptoms in an advanced murine graft-versus-host disease modelIn: Cytotherapy (2023)Online Volltext: dx.doi.org/ (Open Access)
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Maternal antibodies induced by a live attenuated vaccine protect neonatal mice from cytomegalovirusIn: npj Vaccines Jg. 8 (2023) Nr. 1, 8Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Neuropilin-1 identifies a subset of highly activated CD8⁺ T cells during parasitic and viral infectionsIn: PLoS Pathogens Jg. 19 (2023) Nr. 11, e1011837Online Volltext: dx.doi.org/ (Open Access)
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Substantial heterogeneity of inflammatory cytokine production and its inhibition by a triple cocktail of toll-like receptor blockers in early sepsisIn: Frontiers in Immunology Jg. 14 (2023) 1277033
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Treatment with Helicobacter pylori-derived VacA attenuates allergic airway diseaseIn: Frontiers in Immunology Jg. 14 (2023) 1092801Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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B cell expansion hinders the stroma-epithelium regenerative cross talk during mucosal healingIn: Immunity Jg. 55 (2022) Nr. 12, S. 2336 - 2351.e12Online Volltext: dx.doi.org/ (Open Access)
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Bacteria (E. coli) take up ultrasmall gold nanoparticles (2 nm) as shown by different optical microscopic techniques (CLSM, SIM, STORM)In: Nano Select Jg. 3 (2022) Nr. 10, S. 1407 - 1420Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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CD47 restricts antiviral function of alveolar macrophages during influenza virus infectionIn: iScience Jg. 25 (2022) Nr. 12, 105540Online Volltext: dx.doi.org/
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Cell-intrinsic ceramides determine T cell function during melanoma progressionIn: eLife Jg. 11 (2022) e83073Online Volltext: dx.doi.org/ (Open Access)
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DJ-1 depletion prevents immunoaging in T-cell compartmentsIn: EMBO Reports Jg. 23 (2022) Nr. 3, e53302Online Volltext: dx.doi.org/ (Open Access)
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Immune hyporeactivity to bacteria and multiple TLR-ligands, yet no response to checkpoint inhibition in patients just after meeting Sepsis-3 criteriaIn: PLoS ONE Jg. 17 (2022) Nr. 8, e0273247Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Peripheral blood iNKT cell activation correlates with liver damage during acute hepatitis CIn: JCI Insight Jg. 7 (2022) Nr. 2, e155432Online Volltext: dx.doi.org/ (Open Access)
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The Fungal Gut Microbiome Exhibits Reduced Diversity and Increased Relative Abundance of Ascomycota in Severe COVID-19 Illness and Distinct Interconnected Communities in SARS-CoV-2 Positive PatientsIn: Frontiers in Cellular and Infection Microbiology Jg. 12 (2022) 848650Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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The acid ceramidase/ceramide axis controls parasitemia in Plasmodium yoelii-infected mice by regulating erythropoiesisIn: eLife Jg. 11 (2022) e77975Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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The interplay of thyroid hormones and the immune system : where we stand and why we need to know about itIn: European Journal of Endocrinology (EJE) Jg. 168 (2022) Nr. 5, S. R65 - R77Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Uptake of Functional Ultrasmall Gold Nanoparticles in 3D Gut Cell ModelsIn: Small (2022) 2201167Online Volltext: dx.doi.org/ (Open Access)
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A Pro-Inflammatory Gut Microbiome Characterizes SARS-CoV-2 Infected Patients and a Reduction in the Connectivity of an Anti-Inflammatory Bacterial Network Associates With Severe COVID-19In: Frontiers in Cellular and Infection Microbiology Jg. 11 (2021) 747816Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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A combination of anti-pd-l1 treatment and therapeutic vaccination facilitates improved retroviral clearance via reactivation of highly exhausted t cellsIn: mBio Jg. 12 (2021) Nr. 1, S. e02121 - 20Online Volltext: dx.doi.org/ (Open Access)
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Epigenetic mechanisms mediating cell state transitions in chondrocytesIn: Journal of Bone and Mineral Research (JBMR) Jg. 36 (2021) Nr. 5, S. 968 - 985Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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GPR15 facilitates recruitment of regulatory T cells to promote colorectal cancerIn: Cancer Research Jg. 81 (2021) Nr. 11, S. 2970 - 2982Online Volltext: dx.doi.org/; Online Volltext: dx.doi.org/ (Open Access)
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Heroin-assisted treatment of heroin-addicted patients normalizes regulatory T cells but does not restore CD4⁺ T cell proliferationIn: Addiction Biology Jg. 26 (2021) Nr. 4, S. e12998Online Volltext: dx.doi.org/ (Open Access)
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IL-33 Drives Expansion of Type 2 Innate Lymphoid Cells and Regulatory T Cells and Protects Mice From Severe, Acute ColitisIn: Frontiers in Immunology Jg. 12 (2021) 669787Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Inhibition of TLR4 Signaling Impedes Tumor Growth in Colitis-Associated Colon CancerIn: Frontiers in Immunology Jg. 12 (2021) 669747Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Interleukin-33 signaling exacerbates experimental infectious colitis by enhancing gut permeability and inhibiting protective Th17 immunityIn: Mucosal Immunology Jg. 14 (2021) Nr. 4, S. 923 - 936Online Volltext: dx.doi.org/ (Open Access)
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Modulating gut microbiota in a mouse model of Graves’ orbitopathy and its impact on induced diseaseIn: Microbiome Jg. 9 (2021) Nr. 1, 45Online Volltext: dx.doi.org/ (Open Access)
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Neuropilin-1 is expressed on highly activated cd4+ effector t cells and dysfunctional cd4+ conventional t cells from naive miceIn: The Journal of Immunology (JI) Jg. 207 (2021) Nr. 5, S. 1288 - 1297Online Volltext: dx.doi.org/ (Open Access)
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Permissive HLA-DPB1 mismatches in HCT depend on immunopeptidome divergence and editing by HLA-DMIn: Blood Jg. 137 (2021) Nr. 7, S. 923 - 928Online Volltext: dx.doi.org/ (Open Access)
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CEACAM1 regulates CD8⁺ T cell immunity and protects from severe pathology during Citrobacter rodentium induced colitisIn: Gut Microbes Jg. 11 (2020) Nr. 6, S. 1790 - 1805Online Volltext: dx.doi.org/ (Open Access)
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Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathologyIn: PLoS Pathogens Jg. 16 (2020) Nr. 3, e1008340Online Volltext: dx.doi.org/ (Open Access)
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Common Pathways in Depression and Obesity : The Role of Gut Microbiome and DietsIn: Current Behavioral Neuroscience Reports Jg. 7 (2020) Nr. 1, S. 15 - 21Online Volltext: dx.doi.org/
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Depletion of Foxp3⁺ regulatory T cells is accompanied by an increase in the relative abundance of Firmicutes in the murine gut microbiomeIn: Immunology Jg. 159 (2020) Nr. 3, S. 344 - 353Online Volltext: dx.doi.org/ (Open Access)
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Effective Activation of Human Antigen-Presenting Cells and Cytotoxic CD8+ T Cells by a Calcium Phosphate-Based Nanoparticle Vaccine Delivery SystemIn: Vaccines Jg. 8 (2020) Nr. 1, 110Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Endogenous CD83 Expression in CD4⁺ Conventional T Cells Controls Inflammatory Immune ResponsesIn: The Journal of Immunology (JI) Jg. 204 (2020) Nr. 12, S. 3217 - 3226Online Volltext: dx.doi.org/ (Open Access)
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Gute Mikroben, schlechte Mikroben : Ist die Darm-Mikrobiota Teil des Problems oder die Lösung bei chronisch-entzündlichen Darmerkrankungen?In: Unikate: Berichte aus Forschung und Lehre (2020) Nr. 54: Medizin: Infektionskrankheiten - ein globales Problem, S. 48 - 61Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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In vivo biodistribution of calcium phosphate nanoparticles after intravascular, intramuscular, intratumoral, and soft tissue administration in mice investigated by small animal PET/CTIn: Acta Biomaterialia Jg. 109 (2020) S. 244 - 253Online Volltext: dx.doi.org/
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A network of trans-cortical capillaries as mainstay for blood circulation in long bonesIn: Nature Metabolism Jg. 1 (2019) Nr. 2, S. 236 - 250Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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A tumor-peptide–based nanoparticle vaccine elicits efficient tumor growth control in antitumor immunotherapyIn: Molecular Cancer Therapeutics Jg. 18 (2019) Nr. 6, S. 1069 - 1080Online Volltext: dx.doi.org/ (Open Access)
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Diverse immunomodulatory effects of individual IFNα subtypes on virus-specific CD8⁺ T cell responsesIn: Frontiers in Immunology Jg. 10 (2019) 2255Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Early suppression of peripheral mononuclear blood cells in sepsis in response to stimulation with cytomegalovirus, OKT3, and pokeweed mitogenIn: Journal of Applied Physiology Jg. 127 (2019) Nr. 6, S. 1539 - 1547Online Volltext: dx.doi.org/ (Open Access)
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Intestinal acid sphingomyelinase protects from severe pathogen-driven colitisIn: Frontiers in Immunology Jg. 10 (2019) 1386Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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MicroRNA-183 and microRNA-96 are associated with autoimmune responses by regulating T cell activationIn: Journal of Autoimmunity Jg. 96 (2019) S. 94 - 103Online Volltext: dx.doi.org/
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T cell-specific overexpression of acid sphingomyelinase results in elevated T cell activation and reduced parasitemia during Plasmodium yoelii infectionIn: Frontiers in Immunology Jg. 10 (2019) S. 1225Online Volltext: dx.doi.org/ (Open Access)
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The IL-33/ST2 pathway shapes the regulatory T cell phenotype to promote intestinal cancerIn: Mucosal Immunology Jg. 12 (2019) Nr. 4, S. 990 - 1003Online Volltext: dx.doi.org/ (Open Access)
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A systematic electron microscopic study on the uptake of barium sulphate nano-, submicro-, microparticles by bone marrow-derived phagocytosing cellsIn: Acta Biomaterialia Jg. 80 (2018) S. 352 - 363Online Volltext: dx.doi.org/
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CEACAM1 promotes CD8⁺ T cell responses and improves control of a chronic viral infectionIn: Nature Communications Jg. 9 (2018) 2561Online Volltext: dx.doi.org/ (Open Access)
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IL-1β as mucosal vaccine adjuvant : the specific induction of tissue-resident memory T cells improves the heterosubtypic immunity against influenza A virusesIn: Mucosal Immunology Jg. 11 (2018) Nr. 4, S. 1265 - 1278Online Volltext: dx.doi.org/ (Open Access)
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Induction of Type I Interferons by Therapeutic Nanoparticle-Based Vaccination Is Indispensable to Reinforce Cytotoxic CD8+ T Cell Responses During Chronic Retroviral InfectionIn: Frontiers in Immunology Jg. 9 (2018) 614Online Volltext: dx.doi.org/ (Open Access)
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Acquired IFNγ 3 resistance impairs anti-Tumor immunity and gives rise to T-cell-resistant melanoma lesionsIn: Nature Communications Jg. 8 (2017) 15440Online Volltext: dx.doi.org/ (Open Access)
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Avidin-conjugated calcium phosphate nanoparticles as a modular targeting system for the attachment of biotinylated molecules in vitro and in vivoIn: Acta Biomaterialia Jg. 57 (2017) S. 414 - 425Online Volltext: dx.doi.org/
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Conventional CD11chigh Dendritic Cells Are Important for T Cell Priming during the Initial Phase of Plasmodium yoelii Infection, but Are Dispensable at Later Time PointsIn: Frontiers in Immunology Jg. 8 (2017) 1333Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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DC-Derived IL-10 Modulates Pro-inflammatory Cytokine Production and Promotes Induction of CD4+IL-10+ Regulatory T Cells during Plasmodium yoelii InfectionIn: Frontiers in Immunology Jg. 8 (2017) 152Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Delivery of the TLR ligand poly(I:C) to liver cells in vitro and in vivo by calcium phosphate nanoparticles leads to a pronounced immunostimulationIn: Acta Biomaterialia Jg. 64 (2017) S. 401 - 410Online Volltext: dx.doi.org/
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Differential expression of GPR15 on T cells during ulcerative colitisIn: JCI Insight Jg. 2 (2017) Nr. 8, e90585Online Volltext: dx.doi.org/ (Open Access)
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Helminth-induced intestinal inflammation facilitates tumor growth and progression in colitis-associated colon cancer
47th Annual meeting [of the] German Society of Immunology (DGfI), 15.–17.09.2017, Erlangen,In: European Journal of Immunology Jg. 47 (2017) Nr. S2: 47th Annual Meeting of the German Society for Immunology, 12–15 September, 2017, Erlangen, Germany, S. 67Online Volltext: dx.doi.org/ -
Hypoxia enhances immunosuppression by inhibiting CD4+ Effector T cell function and promoting treg activityIn: Cellular Physiology and Biochemistry Jg. 41 (2017) Nr. 4, S. 1271 - 1284Online Volltext: dx.doi.org/ (Open Access)
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Intestinal helminth infection drives carcinogenesis in colitis-associated colon cancerIn: PLoS Pathogens Jg. 13 (2017) Nr. 9, e1006649Online Volltext: dx.doi.org/ (Open Access)
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Local delivery of siRNA-loaded calcium phosphate nanoparticles abates pulmonary inflammationIn: Nanomedicine: Nanotechnology, Biology, and Medicine Jg. 13 (2017) Nr. 8, S. 2395 - 2403Online Volltext: dx.doi.org/
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Quantitative Comparison of Abundance Structures of Generalized Communities : from B-Cell Receptor Repertoires to MicrobiomesIn: PLoS Computational Biology Jg. 13 (2017) Nr. 1, e1005362Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Sphingosine 1-Phosphate- and C-C Chemokine Receptor 2-Dependent Activation of CD4+ Plasmacytoid Dendritic Cells in the Bone Marrow Contributes to Signs of Sepsis-Induced ImmunosuppressionIn: Frontiers in Immunology Jg. 8 (2017) 1622Online Volltext: dx.doi.org/ (Open Access)
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Colonic gene silencing using siRNA-loaded calcium phosphate/PLGA nanoparticles ameliorates intestinal inflammation in vivoIn: Journal of Controlled Release Jg. 222 (2016) S. 86 - 96Online Volltext: dx.doi.org/
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Combination of nanoparticle‑based therapeutic vaccination and transient ablation of regulatory T cells enhances anti‑viral immunity during chronic retroviral infectionIn: Retrovirology Jg. 13 (2016) 24Online Volltext: dx.doi.org/ (Open Access)
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Efficient nucleic acid delivery to murine regulatory T cells by gold nanoparticle conjugatesIn: Scientific Reports Jg. 6 (2016) 28709Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Extracellular Adenosine Production by ecto-5'-Nucleotidase (CD73) Enhances Radiation-Induced Lung FibrosisIn: Cancer Research Jg. 76 (2016) Nr. 10, S. 3045 - 3056Online Volltext: dx.doi.org/ (Open Access)
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IL-10 downregulates CXCR3 expression on Th1 cells and interferes with their migration to intestinal inflammatory sitesIn: Mucosal Immunology Jg. 9 (2016) Nr. 5, S. 1263 - 1277Online Volltext: dx.doi.org/ (Open Access)
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Mitochondrial DNA : an endogenous trigger for immune paralysisIn: Anesthesiology Jg. 124 (2016) Nr. 4, S. 923 - 933Online Volltext: dx.doi.org/
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Nanoparticles as transfection agents : a comprehensive study with ten different cell linesIn: RSC Advances Jg. 6 (2016) Nr. 22, S. 18102 - 18112Online Volltext: dx.doi.org/ (Open Access)
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Plasmodium yoelii infection of BALB/c mice results in expansion rather than induction of CD4+ Foxp3+ regulatory T cellsIn: Immunology Jg. 148 (2016) Nr. 2, S. 197 - 205Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Targeting Antigens to Dec-205 on Dendritic Cells Induces Immune Protection in Experimental Colitis in MiceIn: European Journal of Microbiology and Immunology Jg. 6 (2016) Nr. 1, S. 1 - 8Online Volltext: dx.doi.org/ (Open Access)
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Gene silencing of the pro-inflammatory cytokine TNF-alpha with siRNA delivered by calcium phosphate nanoparticles, quantified by different methodsIn: Journal of Materials Chemistry B: Materials for Biology and Medicine Jg. 3 (2015) Nr. 36, S. 7186 - 7193Online Volltext: dx.doi.org/ (Open Access)
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IL10-Deficiency in CD4⁺ T Cells Exacerbates the IFNγ and IL17 Response During Bacteria Induced ColitisIn: Cellular Physiology and Biochemistry Jg. 36 (2015) Nr. 4, S. 1259 - 1273Online Volltext: dx.doi.org/ (Open Access)
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Relevance of Foxp3+ regulatory T cells for early and late phases of murine sepsisIn: Immunology Jg. 146 (2015) Nr. 1, S. 144 - 156Online Volltext: dx.doi.org/ (Open Access)
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The potential of nanoparticles for the immunization against viral infectionsIn: Journal of Materials Chemistry B: Materials for Biology and Medicine Jg. 3 (2015) Nr. 24, S. 4767 - 4779Online Volltext: dx.doi.org/ (Open Access)
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Three-dimensional tumor spheroids for in vitro analysis of bacteria as gene delivery vectors in tumor therapyIn: Microbial Cell Factories Jg. 14 (2015) 199Online Volltext: dx.doi.org/ (Open Access)
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Virus-induced type i interferon deteriorates control of systemic pseudomonas aeruginosa infectionIn: Cellular Physiology and Biochemistry Jg. 36 (2015) Nr. 6, S. 2379 - 2392Online Volltext: dx.doi.org/ (Open Access)
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Calcium phosphate nanoparticles show an effective activation of the innate immune response in vitro and in vivo after functionalization with flagellinIn: Virologica Sinica Jg. 29 (2014) Nr. 1, S. 33 - 39Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Distinct Kinetics in the Frequency of Peripheral CD4+ T Cells in Patients with Ulcerative Colitis Experiencing a Flare during Treatment with Mesalazine or with a Herbal Preparation of Myrrh, Chamomile, and Coffee CharcoalIn: PLoS ONE Jg. 9 (2014) Nr. 8, e104257Online Volltext: dx.doi.org/ (Open Access)
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Hydrocortisone Fails to Abolish NF-κB1 Protein Nuclear Translocation in Deletion Allele Carriers of the NFKB1 Promoter Polymorphism (-94ins/delATTG) and Is Associated with Increased 30-Day Mortality in Septic ShockIn: PLoS ONE Jg. 9 (2014) Nr. 8, e104953Online Volltext: dx.doi.org/ (Open Access)
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Prophylactic and therapeutic vaccination with a nanoparticle-based peptide vaccine induces efficient protective immunity during acute and chronic retroviral infectionIn: Nanomedicine: Nanotechnology, Biology, and Medicine Jg. 10 (2014) Nr. 8, S. 1787 - 1798Online Volltext: dx.doi.org/
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Regulatory T cells and T-cell-derived IL-10 interfere with effective anti-cytomegalovirus immune responseIn: Immunology and Cell Biology Jg. 92 (2014) Nr. 10, S. 860 - 871Online Volltext: dx.doi.org/
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The sympathetic nervous system modulates CD4+Foxp3+ regulatory T cells via noradrenaline-dependent apoptosis in a murine model of lymphoproliferative diseaseIn: Brain, Behavior and Immunity Jg. 38 (2014) S. 100 - 110Online Volltext: dx.doi.org/
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The type of adjuvant strongly influences the T-cell response during nanoparticle-based immunizationIn: Human Vaccines & Immunotherapeutics Jg. 10 (2014) Nr. 1, S. 164 - 169
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Thorax irradiation triggers a local and systemic accumulation of immunosuppressive CD4+ FoxP3+ regulatory T cellsIn: Radiation Oncology Jg. 9 (2014) Nr. 1, 98Online Volltext: dx.doi.org/ (Open Access)
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Transient ablation of regulatory T cells improves antitumor immunity in colitis-associated colon cancerIn: Cancer Research Jg. 74 (2014) Nr. 16, S. 4258 - 4269Online Volltext: dx.doi.org/
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An increased alveolar CD4 + CD25 + Foxp3 + T-regulatory cell ratio in acute respiratory distress syndrome is associated with increased 30-day mortalityIn: Intensive Care Medicine Jg. 39 (2013) Nr. 10, S. 1743 - 1751Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Applications of nanoparticles for treating cutaneous infectionIn: Journal of Investigative Dermatology Jg. 133 (2013) Nr. 5, S. 1133 - 1135Online Volltext: dx.doi.org/ (Open Access)
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Immunization with biodegradable nanoparticles efficiently induces cellular immunity and protects against influenza virus infectionIn: The Journal of Immunology (JI) Jg. 190 (2013) Nr. 12, S. 6221 - 6229Online Volltext: dx.doi.org/ (Open Access)
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Mechanism of the uptake of cationic and anionic calcium phosphate nanoparticles by cellsIn: Acta Biomaterialia Jg. 9 (2013) Nr. 7, S. 7527 - 7535Online Volltext: dx.doi.org/
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Calcium phosphate nanoparticles as versatile carrier for small and large molecules across cell membranesIn: Journal of Nanoparticle Research Jg. 14 (2012) Nr. 6, 0910Online Volltext: dx.doi.org/
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Cell targeting by antibody-functionalized calcium phosphate nanoparticlesIn: Journal of Materials Chemistry Jg. 22 (2012) Nr. 2, S. 396 - 404Online Volltext: dx.doi.org/
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Gut inflammation can boost horizontal gene transfer between pathogenic and commensal EnterobacteriaceaeIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 109 (2012) Nr. 4, S. 1269 - 1274Online Volltext: dx.doi.org/ (Open Access)
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HMGB1 conveys immunosuppressive characteristics on regulatory and conventional T cellsIn: International Immunology Jg. 24 (2012) Nr. 8, S. 485 - 494Online Volltext: dx.doi.org/ (Open Access)
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Neuropilin 1 deficiency on CD4⁺Foxp3⁺ regulatory T cells impairs mouse melanoma growthIn: Journal of Experimental Medicine (JEM) Jg. 209 (2012) Nr. 11, S. 2001 - 2016Online Volltext: dx.doi.org/ (Open Access)
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Opioid maintenance therapy restores CD4⁺ T cell function by normalizing CD4⁺CD25hⁱgh regulatory T cell frequencies in heroin userIn: Brain, Behavior and Immunity Jg. 26 (2012) Nr. 6, S. 972 - 978Online Volltext: dx.doi.org/
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Strong impact of CD4 ⁺Foxp3 ⁺ regulatory T cells and limited effect of T cell-derived IL-10 on pathogen clearance during Plasmodium yoelii infectionIn: The Journal of Immunology (JI) Jg. 188 (2012) Nr. 11, S. 5467 - 5477Online Volltext: dx.doi.org/ (Open Access)
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ATP Inhibits the Generation and Function of Regulatory T Cells Through the Activation of Purinergic P2X ReceptorsIn: Science Signaling Jg. 4 (2011) Nr. 162, ra12Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Generation and function of immunosuppressive human and murine CD8⁺ T cells by transforming growth factor-β and retinoic acidIn: Immunology Jg. 134 (2011) Nr. 1, S. 82 - 92Online Volltext: dx.doi.org/ (Open Access)
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In vitro induced CD8+ regulatory T cells inhibit skin inflammationIn: European Journal of Microbiology and Immunology Jg. 1 (2011) Nr. 3, S. 208 - 214Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Quantitative determination of the composition of multi-shell calcium phosphate-oligonucleotide nanoparticles and their application for the activation of dendritic cellsIn: Acta Biomaterialia Jg. 7 (2011) Nr. 11, S. 4029 - 4036Online Volltext: dx.doi.org/
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Inflammation in vivo is modulated by gpr83 isoform-4 but not GPR83 isoform-1 expression in regulatory T cellsIn: Genes and Immunity Jg. 11 (2010) Nr. 4, S. 357 - 361Online Volltext: dx.doi.org/
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Local induction of immunosuppressive CD⁸ T cells in the gut-associated lymphoid tissuesIn: PLoS ONE Jg. 5 (2010) Nr. 10, e15373Online Volltext: dx.doi.org/ (Open Access)
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Retinoic acid-induced gut tropism improves the protective capacity of Treg in acute but not in chronic gut inflammationIn: European Journal of Immunology Jg. 40 (2010) Nr. 9, S. 2539 - 2548Online Volltext: dx.doi.org/ (Open Access)
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T cells, dendritic cells and epithelial cells in intestinal homeostasisIn: International Journal of Medical Microbiology (IJMM) Jg. 300 (2010) Nr. 1, S. 11 - 18Online Volltext: dx.doi.org/
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The use of calcium phosphate nanoparticles encapsulating toll-like receptor ligands and the antigen hemagglutinin to induce dendritic cell maturation and T cell activationIn: Biomaterials Jg. 31 (2010) Nr. 21, S. 5627 - 5633Online Volltext: dx.doi.org/
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CD4⁺Foxp3⁺ regulatory T cell expansion induced by antigen-driven interaction with intestinal epithelial cells independent of local dendritic cellsIn: Gut Jg. 58 (2009) Nr. 2, S. 211 - 219Online Volltext: dx.doi.org/
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CD83 expression in CD4⁺ T cells modulates inflammation and autoimmunityIn: The Journal of Immunology (JI) Jg. 180 (2008) Nr. 9, S. 5890 - 5897Online Volltext: dx.doi.org/ (Open Access)
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The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxinsIn: Nature Jg. 453 (2008) Nr. 7191, S. 106 - 109Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Chronic antigen stimulation in vivo induces a distinct population of antigen-specific Foxp3⁻CD25⁻ regulatory T cellsIn: The Journal of Immunology (JI) Jg. 179 (2007) Nr. 12, S. 8059 - 8068Online Volltext: dx.doi.org/ (Open Access)
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Probiotic Escherichia coli Nissle 1917 inhibits leaky gut by enhancing mucosal integrityIn: PLoS ONE Jg. 2 (2007) Nr. 12, e1308Online Volltext: dx.doi.org/ (Open Access)
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Autoimmune-Mediated Intestinal Inflammation-Impact and Regulation of Antigen-Specific CD8⁺ T CellsIn: Gastroenterology Jg. 131 (2006) Nr. 2, S. 510 - 524Online Volltext: dx.doi.org/
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Cd14, Gbp1, and Pla2g2a : Three major candidate genes for experimental IBD identified by combining QTL and microarray analysesIn: Physiological Genomics Jg. 25 (2006) Nr. 3, S. 426 - 434Online Volltext: dx.doi.org/ (Open Access)
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G protein-coupled receptor 83 overexpression in naive CD4 ⁺CD25⁻ T cells leads to the induction of Foxp3⁺ regulatory T cells in vivoIn: The Journal of Immunology (JI) Jg. 177 (2006) Nr. 1, S. 209 - 215Online Volltext: dx.doi.org/ (Open Access)
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Signatures of human regulatory T cells : An encounter with old friends and new playersIn: Genome Biology Jg. 7 (2006) Nr. 7, R54Online Volltext: dx.doi.org/ (Open Access)
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CD4⁺ T cell mediated intestinal immunity : Chronic inflammation versus immune regulationIn: Gut Jg. 54 (2005) Nr. 1, S. 60 - 69Online Volltext: dx.doi.org/ (Open Access)
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Mechanisms of central and peripheral T-cell tolerance : An updateIn: Transfusion Medicine and Hemotherapy Jg. 32 (2005) Nr. 6, S. 384 - 399Online Volltext: dx.doi.org/
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On the edge of autoimmunity : T-cell stimulation by steady-state dendritic cells prevents autoimmune diabetesIn: Diabetes Jg. 54 (2005) Nr. 12, S. 3395 - 3401Online Volltext: dx.doi.org/
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The host response to the probiotic Escherichia coli strain Nissle 1917 : Specific up-regulation of the proinflammatory chemokine MCP-1In: BMC Medical Genetics Jg. 6 (2005) 43Online Volltext: dx.doi.org/ (Open Access)
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Frontline: Neuropilin-1 : A surface marker of regulatory T cellsIn: European Journal of Immunology Jg. 34 (2004) Nr. 3, S. 623 - 630Online Volltext: dx.doi.org/ (Open Access)
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The Mycoplasma-derived macrophage-activating 2-kilodalton lipopeptide triggers global immune activation on nasal mucosa-associated lymphoid tissuesIn: Infection and Immunity Jg. 72 (2004) Nr. 12, S. 6978 - 6986Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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EditorialIn: Unikate: Berichte aus Forschung und Lehre (2020) Nr. 54: Medizin: Infektionskrankheiten - ein globales Problem, S. 6 - 7Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Editorial : Cancer, drugs, and bugs—Bacteriotherapy on the rise?In: Journal of Leukocyte Biology (JLB) Jg. 103 (2018) Nr. 5, S. 795 - 797Online Volltext: dx.doi.org/
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Graduiertenkollegs sind ein großes Plus : Ein Gespräch mit der Sprecherin des Graduiertenkollegs „Immunantwort in Infektionskrankheiten“ (GRK 1949), Prof. Dr. Astrid Westendorf und der Koordinatorin des Kollegs, Daniela Catrini M.A.In: Unikate: Berichte aus Forschung und Lehre (2020) Nr. 54: Medizin: Infektionskrankheiten - ein globales Problem, S. 82 - 85Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Das vakuolsisierende Zytotoxin (VacA) reduziert Atemwegsinflammation, Mukusproduktion und subepitheliale Fibrose in einem therapeutischen Modell
63. Kongress der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e. V.,In: Pneumologie Jg. 77 (2023) Nr. S 01, S. S62Online Volltext: dx.doi.org/ -
Session 5: Biomaterials - Inorganic : Calcium phosphate nanoparticles as a delivery of bioactive compounds to the liver and for imaging and vaccination
Annual Conference of the German Society for Biomaterials e.V., 08,-10.11.2018, Braunschweig-Stöckheim,In: Biomedical engineering = Biomedizinische Technik Jg. 64 (2019) Nr. s1: Abstracts of the 2018 Annual Meeting of the German Society for Biomaterials, S. 36 - 40Online Volltext: dx.doi.org/ (Open Access) -
Analysis of the gut microbiome in Foxp3+Regulatory T cell depleted mice
47th Annual meeting [of the] German Society of Immunology (DGfI), 15.–17.09.2017, Erlangen,In: European Journal of Immunology Jg. 47 (2017) Nr. S2: 47th Annual Meeting of the German Society for Immunology, 12–15 September, 2017, Erlangen, Germany, S. 212Online Volltext: dx.doi.org/ (Open Access) -
Loss or therapeutic inhibition of extracellular adenosine production by ecto-5 -nucleotidase(CD73) attenuates radiation-induced lung fibrosis
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Ein Vergleich der Genstummschaltungseffizienz unterschiedlicher nanopartikulärer SystemeIn: BioNanoMaterials Jg. 15 (2014) Nr. S 1, S. 80Online Volltext: dx.doi.org/
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Prophylaktische Vakzinierung gegen Tumoren mit funktionalisierten Calciumphosphat-Nanopartikeln in einem murinen Tumortransplantations- Modell
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Thorax irradiation triggers a local and systemic accumulation of immunosuppressive CD4+FoxP3+regulatory T cells
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Whole thorax irradiation initiates a local and systemic accumulation of immunosuppressive FoxP3+regulatory T cells
23rd Biennial Congress of the European Association for Cancer Research, 05.–08.07.2014, München,In: European Journal of Cancer (EJC) Jg. 50 (2014) Nr. Suppl. 5, S. S223Online Volltext: dx.doi.org/ -
Effective immunmodulation by biodegradable calcium phosphate nanoparticles confers strong antiviral protection
65th Annual Meeting of the German Society for Hygiene and Microbiology (DGHM), 22.-25.09.2013, Rostock,In: International Journal of Medical Microbiology (IJMM) Jg. 303 (2013) Nr. Suppl. 1, S. 38 - 38 -
Impact of IL-10 in Citrobacter rodentium induced intestinal inflammation
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Lymphocytes play a role in radiation-induced pneumopathyIn: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 188 (2012) Nr. Suppl.1: Abstract-Band DEGRO 2014, S. 126 - 127Online Volltext: dx.doi.org/
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Intestinal epithelial antigen induces CD4⁺ T cells with regulatory phenotype in a transgenic autoimmune mouse modelIn: Inflammatory Bowel Disease: Genetics, Barrier Function, Immunologic Mechanisms, and Microbial Pathways / International Symposium Inflammatory Bowel Disease: Research Drives Clinics Genetics, Barrier Function, Immunological and Microbial Pathways, 01.-03.09.2005, Münster / Domschke, Wolfram W. (Hrsg.) 2006, S. 401 - 406Online Volltext: dx.doi.org/
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Cytomegalovirus infection aggravates intestinal inflammation during colitis and impairs the convalescence of the intestinal niche
Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI) ; 26-29 September, 2023, Strasbourg, France,In: European Journal of Immunology Jg. 53 (2023) Nr. S2, Special issue: Abstracts: Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), 26–29 September, 2023, Strasbourg, France, S. 354Online Volltext: dx.doi.org/ (Open Access) -
Impact of chronic intestinal inflammation on colonic immune responses to secondary challenge with Citrobacter rodentium
Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI) ; 26-29 September, 2023, Strasbourg, France,In: European Journal of Immunology Jg. 53 (2023) Nr. S2, Special issue: Abstracts: Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), 26–29 September, 2023, Strasbourg, France, S. 362Online Volltext: dx.doi.org/ (Open Access) -
Respiratory but not systemic viral infection induces tumour growth inhibition through CD8+T-cell activation
Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI) ; 26-29 September, 2023, Strasbourg, France,In: European Journal of Immunology Jg. 53 (2023) Nr. S2, Special issue: Abstracts: Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), 26–29 September, 2023, Strasbourg, France, S. 189Online Volltext: dx.doi.org/ (Open Access) -
Vacuolating Cytotoxin A (VacA) : Therapeutic Potential of a Helicobacter Derived Molecule for Asthma
International Conference of the American Thoracic Society (ATS) 2022 ; May 13-18, 2022, San Francisco, CA, USA,In: American Journal of Respiratory and Critical Care Medicine (AJRCCM) Jg. 205 (2022) Nr. Supplement, A3749Online Volltext: dx.doi.org/