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Prof. Dr. med. Ulrich Frey

Funktionen

  • Wiss. Mitarbeiterinnen/Mitarbeiter, Klinik für Anästhesiologie und Intensivmedizin

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Komanek, Thomas; Rabis, Marco; Omer, Saed; Peters, Jürgen; Frey, Ulrich H.
    Quantification of left ventricular ejection fraction and cardiac output using a novel semi-automated echocardiographic method : a prospective observational study in coronary artery bypass patients
    In: BMC Anesthesiology Jg. 23 (2023) Nr. 1, 65
    Online Volltext: dx.doi.org/ (Open Access)
  • Fassbender, Philipp; Klenke, Stefanie; Omer, Saed; Komanek, Tomas; Ochsenfarth, Crista; Frey, Ulrich; Peters, Jürgen
    Polymorphic Variants in the GRK5 Gene Promoter Are Associated With Diastolic Dysfunction in Coronary Artery Bypass Graft Surgery Patients
    In: Anesthesia & Analgesia Jg. 134 (2022) Nr. 4, S. 858 - 868
    Online Volltext: dx.doi.org/
  • Stegen, Maike; Frey, Ulrich
    The Role of G Protein-Coupled Receptor Kinase 6 Regulation in Inflammation and Pain
    In: International Journal of Molecular Sciences (IJMS) Jg. 23 (2022) Nr. 24, 15880
    Online Volltext: dx.doi.org/ (Open Access)
  • Abel, Frederik; Giebel, Bernd; Frey, Ulrich H.
    Agony of choice : How anesthetics affect the composition and function of extracellular vesicles
    In: Advanced Drug Delivery Reviews Jg. 175 (2021) 113813
    Online Volltext: dx.doi.org/
  • Stegen, Maike; Engler, Andrea; Ochsenfarth, Crista; Manthey, Iris; Peters, Jürgen; Siffert, Winfried; Frey, Ulrich
    Characterization of the G protein-coupled receptor kinase 6 promoter reveals a functional CREB binding site
    In: PLoS ONE Jg. 16 (2021) Nr. 2, S. e0247087
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Klenke, Stefanie; Schiefer, Laura; Peters, Jürgen; Frey, Ulrich
    Postoperative nausea and vomiting : The role of the serotonin transporter 5-HTTLPR polymorphism
    In: European Journal of Anaesthesiology EJA Jg. 38 (2021) Nr. 1, S. 92 - 93
    Online Volltext: dx.doi.org/
  • Abel, Frederik; Murke, Florian; Gaida, Morten; Garnier, Nicolas; Ochsenfarth, Crista; Theiss, Carsten; Thielmann, Matthias Klaus; Kleinbongard, Petra; Giebel, Bernd; Peters, Jürgen; Frey, Ulrich
    Extracellular vesicles isolated from patients undergoing remote ischemic preconditioning decrease hypoxia-evoked apoptosis of cardiomyoblasts after isoflurane but not propofol exposure
    In: PLoS ONE Jg. 15 (2020) Nr. 2, S. e0228948
    Online Volltext: dx.doi.org/ (Open Access)
  • Klenke, Stefanie; de Vries, Gudrun J.; Schiefer, Laura; Seyffert, Nina; Bachmann, Hagen Sjard; Peters, Jürgen; Frey, Ulrich
    Genetic contribution to PONV risk
    In: Anaesthesia Critical Care & Pain Medicine Jg. 39 (2020) Nr. 1, S. 45 - 51
    Online Volltext: dx.doi.org/
  • Klenke, Stefanie; Frey, Ulrich H.
    Genetic variability in postoperative nausea and vomiting : A systematic review
    In: European Journal of Anaesthesiology EJA Jg. 37 (2020) Nr. 11, S. 959 - 968
    Online Volltext: dx.doi.org/ (Open Access)
  • Klenke, Stefanie; Lehmann, Nils; Erbel, Raimund; Jöckel, Karl-Heinz; Siffert, Winfried; Frey, Ulrich; Peters, Jürgen
    Genetic variations in G-protein signal pathways influence progression of coronary artery calcification : Results from the Heinz Nixdorf Recall study
    In: Atherosclerosis Jg. 310 (2020) S. 102 - 108
    Online Volltext: dx.doi.org/
  • Wendt, Daniel; Shehada, Sharaf-Eldin; König, Luisa; Kahlert, Philipp; Frey, Ulrich; Mourad, Fanar; Jakob, Heinz G.; Thielmann, Matthias Klaus; El-Gabry, Mohamed
    Modified implantation height of the Sapien3™ transcatheter heart valve
    In: Minimally Invasive Therapy and Allied Technologies Jg. 29 (2020) Nr. 2, S. 70 - 77
    Online Volltext: dx.doi.org/
  • Benson, Sven; Hagen, Susanne; Hoffmann, Oliver; Pasler, Annika; Bingel, Ulrike; Schedlowski, Manfred; Peters, Jürgen; Elsenbruch-Harnish, Sigrid; Frey, Ulrich
    Can a brief psychological expectancy intervention improve postoperative pain? : A randomized, controlled trial in patients with breast cancer
    In: Pain Jg. 160 (2019) Nr. 7, S. 1562 - 1571
    Online Volltext: dx.doi.org/
  • Frey, Ulrich; Klaassen, Marina; Ochsenfarth, Crista; Murke, Florian; Thielmann, Matthias Klaus; Kottenberg, Eva; Kleinbongard, Petra; Klenke, Stefanie; Engler, Andrea; Heusch, Gerd; Giebel, Bernd; Peters, Jürgen
    Remote ischaemic preconditioning increases serum extracellular vesicle concentrations with altered micro-RNA signature in CABG patients
    In: Acta Anaesthesiologica Scandinavica Jg. 63 (2019) Nr. 4, S. 483 - 492
    Online Volltext: dx.doi.org/
  • Tsagakis, Konstantinos; Janosi, Rolf Alexander; Frey, Ulrich; Schlosser, Thomas Wilfried; Chiesa, Roberto; Rassaf, Tienush; Jakob, Heinz G.
    True Lumen Stabilization to Overcome Malperfusion in Acute Type I Aortic Dissection
    In: Seminars in Thoracic and Cardiovascular Surgery Jg. 31 (2019) Nr. 4, S. 740 - 748
    Online Volltext: dx.doi.org/ (Open Access)
  • Klenke, Stefanie; de Vries, G.J.; Schiefer, L.; Seyffert, N.; Bachmann, Hagen Sjard; Peters, Jürgen; Frey, Ulrich
    CHRM3 rs2165870 polymorphism is independently associated with postoperative nausea and vomiting, but combined prophylaxis is effective
    In: British Journal of Anaesthesia (BJA) Jg. 121 (2018) Nr. 1, S. 58 - 65
    Online Volltext: dx.doi.org/ (Open Access)
  • Klenke, Stefanie; Eul, Sebastian; Peters, Jürgen; Neumann, Till; Adamzik, Michael; Frey, Ulrich
    Circulating miR-192 is a prognostic marker in patients with ischemic cardiomyopathy
    In: Future Cardiology Jg. 14 (2018) Nr. 4, S. 283 - 289
    Online Volltext: dx.doi.org/
  • Engler, Andrea; Dreja, Florian; Köberle, Sarah; Thielmann, Matthias Klaus; Peters, Jürgen; Frey, Ulrich
    Establishment of an easy and straight forward heparinase protocol to analyse circulating and myocardial tissue micro-RNA during coronary artery-bypass-graft surgery
    In: Scientific Reports Jg. 8 (2018) Nr. 1, S. 1361
    Online Volltext: dx.doi.org/ (Open Access)
  • Kleinbongard, Petra; Gedik, N.; Kirca, M.; Stoian, L.; Frey, Ulrich; Zandi, A.; Thielmann, Matthias Klaus; Jakob, Heinz G.; Peters, Jürgen; Kamler, Markus; Heusch, Gerd
    Impact of remote ischemic preconditioning in cardiosurgical patients on contractile and mitochondrial function of right atrial tissue
    In: European Heart Journal Jg. 39 (2018) Nr. Suppl. 1, S. 453
    Online Volltext: dx.doi.org/ (Open Access)
  • Kleinbongard, Petra; Gedik, N.; Frey, Ulrich; Zandi, A.; Thielmann, Matthias Klaus; Jakob, Heinz G.; Peters, Jürgen; Kamler, Markus; Heusch, Gerd
    Improvement of mitochondrial function in human atrial tissue by remote ischemic conditioning
    In: The FASEB Journal Jg. 32 (2018) Nr. S1, S. 580.1
  • Rahmel, Tim; Rump, Katharina; Adamzik, Michael; Peters, Jürgen; Frey, Ulrich
    Increased circulating microRNA-122 is associated with mortality and acute liver injury in the acute respiratory distress syndrome
    In: BMC Anesthesiology Jg. 18 (2018) S. 75
    Online Volltext: dx.doi.org/ (Open Access)
  • Rahmel, Tim; Schäfer, Simon; Frey, Ulrich; Adamzik, Michael; Peters, Jürgen
    Increased circulating microrna-122 is a biomarker for discrimination and risk stratification in patients defined by sepsis-3 criteria
    In: PLoS ONE Jg. 13 (2018) Nr. 5, S. e0197637
    Online Volltext: dx.doi.org/ (Open Access)
  • Kleinbongard, Petra; Gedik, Nilguen; Kirca, Mücella; Stoian, Leanda; Frey, Ulrich; Zandi, Afsaneh; Thielmann, Matthias Klaus; Jakob, Heinz G.; Peters, Jürgen; Kamler, Markus; Heusch, Gerd
    Mitochondrial and contractile function of human right atrial tissue in response to remote ischemic conditioning
    In: Journal of the American Heart Association Jg. 7 (2018) Nr. 15, S. e009540
    Online Volltext: dx.doi.org/ (Open Access)
  • Dirkmann, Daniel; Britten, Martin W.; Frey, Ulrich
    Point-of-Care-Diagnostik in der Traumatologie - Methoden und Evidenz
    In: AINS - Anästhesiologie Intensivmedizin Notfallmedizin Schmerztherapie Jg. 53 (2018) Nr. 6, S. 440 - 457
    Online Volltext: dx.doi.org/
  • Klenke, Stefanie; Engler, Andrea; Ecker, Daniel; Ochsenfarth, Crista; Danowski, Nina; Peters, Jürgen; Siffert, Winfried; Frey, Ulrich
    The GRK2 Promoter Is Regulated by Early-Growth Response Transcription Factor EGR-1
    In: Basic and Clinical Pharmacology and Toxicology (BCPT) Jg. 123 (2018) Nr. 6, S. 660 - 669
    Online Volltext: dx.doi.org/ (Open Access)
  • Lorenz, Benedikt; Peters, Jürgen; Frey, Ulrich
    Alarm-Fatigue - wieviel Alarm verträgt der Mensch?
    In: AINS - Anästhesiologie Intensivmedizin Notfallmedizin Schmerztherapie Jg. 52 (2017) Nr. 7-8, S. 564 - 570
    Online Volltext: dx.doi.org/
  • Kleinbongard, Petra; Gedik, N.; Stoian, L.; Frey, Ulrich; Zandi, A.; Thielmann, Matthias Klaus; Jakob, Heinz G.; Peters, Jürgen; Kamler, Markus; Heusch, Gerd
    Cardioprotection by Remote Ischemic Conditioning in Humans : Improved Contractile Function and Mitochondrial Respiration of Atrial Trabeculae
    In: Circulation Jg. 136 (2017) Nr. Suppl. 1,
  • Hilder, Michael; Herbstreit, Frank; Adamzik, Michael; Beiderlinden, Martin; Bürschen, Markus; Peters, Jürgen; Frey, Ulrich
    Comparison of mortality prediction models in acute respiratory distress syndrome undergoing extracorporeal membrane oxygenation and development of a novel prediction score: the PREdiction of Survival on ECMO Therapy-Score (PRESET-Score).
    In: Critical Care: The Online Intensive Care Journal Jg. 21 (2017) Nr. 1, S. 301
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Thielmann, Matthias Klaus; Sharma, Vikram; Al-Attar, Nawwar; Bulluck, Heerajnarain; Bisleri, Gianluigi; Bunge, Jeroen J.H.; Czerny, Martin; Ferdinandy, Peter; Frey, Ulrich; Heusch, Gerd; Holfeld, Johannes; Kleinbongard, Petra; Kunst, Gudrun; Lang, Irene; Lentini, Salvatore; Madonna, Rosalinda; Meybohm, Patrick; Muneretto, Claudio; Obadia, Jean-Francois; Perrino, Cinzia; Prunier, Fabrice; Sluijter, Joost P.G.; Van Laake, Linda W.; Sousa-Uva, Miguel; Hausenloy, Derek J.
    ESC Joint Working Groups on Cardiovascular Surgery and the Cellular Biology of the Heart Position Paper : Peri-operativemyocardial injury and infarction in patients undergoing coronary artery bypass graft surgery
    In: European Heart Journal Jg. 38 (2017) Nr. 31, S. 2392 - 2411
    Online Volltext: dx.doi.org/ (Open Access)
  • Frey, Ulrich; Klenke, Stefanie; Mitchell, Anna; Knüfermann, Tim; Jakob, Heinz G.; Thielmann, Matthias Klaus; Siffert, Winfried; Peters, Jürgen
    GNAQ TT(-695/-694)GC Polymorphism Is Associated with Increased Gq Expression, Vascular Reactivity, and Myocardial Injury after Coronary Artery Bypass Surgery
    In: Anesthesiology Jg. 127 (2017) Nr. 1, S. 70 - 77
    Online Volltext: dx.doi.org/
  • Kahlert, Philipp; Hildebrandt, Heike A.; Patsalis, Polykarpos Christos; Al-Rashid, Fadi; Janosi, Rolf Alexander; Nensa, Felix; Schlosser, Thomas Wilfried; Schlamann, Marc; Wendt, Daniel; Thielmann, Matthias Klaus; Kottenberg, Eva; Frey, Ulrich; Neuhäuser, Markus; Forsting, Michael; Jakob, Heinz G.; Rassaf, Tienush; Peters, Jürgen; Heusch, Gerd; Kleinbongard, Petra
    No protection of heart, kidneys and brain by remote ischemic preconditioning before transfemoral transcatheter aortic valve implantation : Interim-analysis of a randomized single-blinded, placebo-controlled, single-center trial
    In: International Journal of Cardiology Jg. 231 (2017) S. 248 - 254
    Online Volltext: dx.doi.org/
  • Gedik, Nilgün; Kottenberg, Eva; Thielmann, Matthias Klaus; Frey, Ulrich; Jakob, Heinz G.; Peters, Jürgen; Heusch, Gerd; Kleinbongard, Petra
    Potential humoral mediators of remote ischemic preconditioning in patients undergoing surgical coronary revascularization
    In: Scientific Reports Jg. 7 (2017) S. 12660
    Online Volltext: dx.doi.org/ (Open Access)
  • Gedik, Nilgün; Krüger, Marcus; Thielmann, Matthias Klaus; Kottenberg, Eva; Skyschally, Andreas; Frey, Ulrich; Cario, Elke; Peters, Jürgen; Jakob, Heinz G.; Heusch, Gerd; Kleinbongard, Petra
    Proteomics/phosphoproteomics of left ventricular biopsies from patients with surgical coronary revascularization and pigs with coronary occlusion/reperfusion : Remote ischemic preconditioning
    In: Scientific Reports Jg. 7 (2017) Nr. 1,
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Klenke, Stefanie; Renckhoff, Kristina; Engler, Andrea; Peters, Jürgen; Frey, Ulrich
    Easy-to-use strategy for reference gene selection in quantitative real-time PCR experiments
    In: Naunyn-Schmiedeberg's Archives of Pharmacology Jg. 389 (2016) Nr. 12, S. 1353 - 1366
    Online Volltext: dx.doi.org/
  • Frey, Ulrich; Peters, Jürgen; Esser, Joachim; Schnee, Christoph; Achilles, Marc; Silvanus, Maria-Theresia
    Postoperative nausea and vomiting : The role of the dopamine D2 receptor TaqIA polymorphism
    In: European Journal of Anaesthesiology EJA Jg. 33 (2016) Nr. 2, S. 84 - 89
    Online Volltext: dx.doi.org/
  • Klenke, Stefanie; Frey, Ulrich; Siffert, Winfried; Peters, Jürgen; Engler, Andrea; Buschkamp, Kai; Rump, Katharina
    Characterization of the PLCB1 promoter and regulation by early growth response transcription factor EGR-1
    In: European Journal of Pharmacology Jg. 742 (2014) Nr. 5, S. 8 - 14
    Online Volltext: dx.doi.org/
  • Frey, Ulrich; Muehlschlegel, Jochen D; Ochterbeck, Christoph; Fox, Amanda A; Shernan, Stanton K; Collard, Charles D; Lichtner, Peter; Peters, Jürgen; Body, Simon
    GNAS Gene Variants Affect β-blocker–related Survival after Coronary Artery Bypass Grafting
    In: Anesthesiology Jg. 120 (2014) Nr. 5, S. 1109 - 1117
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Frey, Ulrich; Moebus, Susanne; Möhlenkamp, Stefan; Kälsch, Hagen; Bauer, Marcus; Lehmann, Nils; Nöthen, Markus; Mühleisen, Thomas W; Stang, Andreas; Erbel, Raimund; Jöckel, Karl-Heinz; Peters, Jürgen; Siffert, Winfried
    GNB3 gene 825 TT variant predicts hard coronary events in the population-based Heinz Nixdorf Recall study
    In: Atherosclerosis Jg. 237 (2014) Nr. 2, S. 437 - 442
    Online Volltext: dx.doi.org/
  • Schäfer, Simon; Gessner, Sophia; Scherag, Andre; Rump, Katharina; Frey, Ulrich; Siffert, Winfried; Westendorf, Astrid; Steinmann, Jörg; Peters, Jürgen; Adamzik, Michael
    Hydrocortisone Fails to Abolish NF-κB1 Protein Nuclear Translocation in Deletion Allele Carriers of the NFKB1 Promoter Polymorphism (-94ins/delATTG) and Is Associated with Increased 30-Day Mortality in Septic Shock
    In: PLoS ONE Jg. 9 (2014) Nr. 8, e104953
    Online Volltext: dx.doi.org/ (Open Access)
  • Kottenberg, Eva; Peters, Jürgen; Heusch, Gerd; Jakob, Heinz G.; Heine, Torsten; Thielmann, Matthias Klaus; Kleinbongard, Petra; Frey, Ulrich
    Myocardial protection by remote ischaemic pre-conditioning is abolished in sulphonylurea-treated diabetics undergoing coronary revascularisation
    In: Acta Anaesthesiologica Scandinavica Jg. 58 (2014) Nr. 4, S. 453 - 462
    Online Volltext: dx.doi.org/
  • Heubner, Martin; Kimmig, Rainer; Aktas, Bahriye; Siffert, Winfried; Frey, Ulrich
    The haplotype of three polymorphisms in the SATB1 promoter region impacts survival in breast cancer patients
    In: Oncology Letters Jg. 7 (2014) Nr. 6, S. 2007 - 2012
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Kottenberg, Eva; Dumont, M; Frey, Ulrich; Heine, Torsten; Plicht, Björn; Kahlert, Philipp; Erbel, Raimund; Peters, Jürgen
    The minimally invasive MitraClip(TM) procedure for mitral regurgitation under general anaesthesia : immediate effects on the pulmonary circulation and right ventricular function
    In: Anaesthesia Jg. 69 (2014) Nr. 8, S. 860 - 867
    Online Volltext: dx.doi.org/ (Open Access)
  • Frey, Ulrich; Karlik, J.; Herbstreit, Frank; Peters, Jürgen
    β2-Adrenoceptor gene variants affect vasopressor requirements in patients after thoracic epidural anaesthesia
    In: British Journal of Anaesthesia (BJA) Jg. 112 (2014) Nr. 3, S. 477 - 484
    Online Volltext: dx.doi.org/ (Open Access)
  • Rump, Katharina; Brendt, Peter; Frey, Ulrich; Schäfer, Simon; Siffert, Winfried; Peters, Jürgen; Adamzik, Michael
    Aquaporin 1 and 5 expression evoked by the β2 adrenoreceptor agonist terbutaline and lipopolysaccharide in mice and in the human monocytic cell line THP-1 is differentially regulated
    In: Shock Jg. 40 (2013) Nr. 5, S. 430 - 436
    Online Volltext: dx.doi.org/
  • Klenke, Stefanie; Siffert, Winfried; Frey, Ulrich
    Cloning and characterization of the GNA11 promoter and its regulation by early growth response 1
    In: Basic and Clinical Pharmacology and Toxicology (BCPT) Jg. 113 (2013) Nr. 5, S. 316 - 324
    Online Volltext: dx.doi.org/
  • Danowski, Nina; Manthey, Iris; Jakob, Heinz G.; Siffert, Winfried; Peters, Jürgen; Frey, Ulrich
    Decreased expression of miR-133a but not of miR-1 is associated with signs of heart failure in patients undergoing coronary bypass surgery
    In: Cardiology Jg. 125 (2013) Nr. 2, S. 125 - 130
    Online Volltext: dx.doi.org/
  • Adamzik, Michael; Schäfer, Simon; Frey, Ulrich; Becker, Arne; Kreuzer, Maximiliane; Winning, Sandra; Frede, Stilla; Steinmann, Jörg; Fandrey, Joachim; Zacharowski, Kai; Siffert, Winfried; Peters, Jürgen; Hartmann, Matthias
    The NFKB1 promoter polymorphism (-94ins/delATTG) alters nuclear translocation of NF-κB1 in monocytes after lipopolysaccharide stimulation and is associated with increased mortality in sepsis.
    In: Anesthesiology Jg. 118 (2013) Nr. 1, S. 123 - 133
    Online Volltext: dx.doi.org/
  • El Hindy, Nicolai; Sandalcioglu, Ibrahim Erol; Adamzik, Michael; Peters, Jürgen; Sure, Ulrich; Siffert, Winfried; Bankfalvi, Agnes; Frey, Ulrich; Zhu, Yuan; Lambertz, Nicole; Rump, Katharina
    The functional Aquaporin 1 −783G/C-polymorphism is associated with survival in patients with glioblastoma multiforme
    In: Journal of Surgical Oncology Jg. 108 (2013) Nr. 7, S. 492 - 498
    Online Volltext: dx.doi.org/
  • Dusse, Fabian; Frey, Ulrich; Bilalic, Adisa; Dirkmann, Daniel; Görlinger, Klaus; Siffert, Winfried; Peters, Jürgen
    The GNB3 C825T polymorphism influences platelet aggregation in human whole blood
    In: Pharmacogenetics and Genomics Jg. 22 (2012) Nr. 1, S. 43 - 49
    Online Volltext: dx.doi.org/
  • Adamzik, Michael; Frey, Ulrich H.; Möhlenkamp, Stephan; Scherag, Andre; Waydhas, Christian; Marggraf, Günther; Dammann, Marc; Steinmann, Jörg; Siffert, Winfried; Peters, Jürgen
    Aquaporin 5 gene promoter -1364A/C polymorphism associated with 30-day survival in severe sepsis
    In: Anesthesiology Jg. 114 (2011) Nr. 4, S. 912 - 917
    Online Volltext: dx.doi.org/ (Open Access)
  • Klenke, Stefanie; Siffert, Winfried; Frey, Ulrich
    Characterization of the GNA11 promoter and regulation by Egr-1
    In: Naunyn-Schmiedeberg's Archives of Pharmacology Jg. 383 (2011) Nr. Suppl. 1, S. 29 - 30
  • Adamzik, Michael; Langemeier, Tanja; Frey, Ulrich; Görlinger, Klaus; Saner, Fuad; Eggebrecht, Holger; Peters, Jürgen; Hartmann, Matthias
    Comparison of Thrombelastometry with Simplified Acute Physiology Score II and Sequential Organ Failure Assessment Scores for the Prediction of 30-Day Survival : A Cohort Study
    In: Shock Jg. 35 (2011) Nr. 4, S. 339 - 342
    Online Volltext: dx.doi.org/ (Open Access)
  • Frey, Ulrich; Kottenberg, Eva; Kamler, Markus; Leineweber, Kirsten; Manthey, I.; Heusch, Gerd; Siffert, Winfried; Peters, Jürgen
    Genetic interactions in the β-adrenoceptor/G-protein signal transduction pathway and survival after coronary artery bypass grafting : a pilot study
    In: British Journal of Anaesthesia (BJA) Jg. 107 (2011) Nr. 6, S. 869 - 878
    Online Volltext: dx.doi.org/ (Open Access)
  • El Hindy, Nicolai; Sandalcioglu, Ibrahim Erol; Siffert, Winfried; Sure, Ulrich; Zhu, Yuan; Adamzik, Michael; Frey, Ulrich; Lambertz, Nicole
    Role of the GNAS1 T393C polymorphism in patients with glioblastoma multiforme
    In: Journal of Clinical Neuroscience Jg. 18 (2011) Nr. 11, S. 1495 - 1499
    Online Volltext: dx.doi.org/
  • Adamzik, Michael; Schaefer, S.; Frey, Ulrich; Becker, A.; Kreutzer, M.; Winning, S.; Frede, Stilla; Steinmann, Jörg; Fandrey, Joachim; Zacharowski, K.; Siffert, Winfried; Peters, Jürgen; Hartmann, Matthias
    The NFKB1 promoter polymorphism (94ins/delATTG) alters nuclear translocation of NF-KB1 in monocytes following lipopolysaccharide stimulation and is associated with increased mortality in sepsis
    In: Infection - A Journal of Infectious Disease Jg. 39 (2011) Nr. Suppl. 2, S. 102
  • Bergmann, Lars; Kahlert, Philipp; Eggebrecht, Holger; Frey, Ulrich; Peters, Jürgen; Kottenberg, Eva
    Transfemoral aortic valve implantation under sedation and monitored anaesthetic care : a feasibility study
    In: Anaesthesia Jg. 66 (2011) Nr. 11, S. 977 - 982
    Online Volltext: dx.doi.org/
  • Klenke, Stefanie; Tan, Susanne; Hahn, Susanne; Mann, Klaus; Hauner, Hans; Manthey, Iris; Peters, Jürgen; Siffert, Winfried; Frey, Ulrich
    A functional GNAQ promoter haplotype is associated with altered Gq expression and with insulin resistance and obesity in women with polycystic ovary syndrome
    In: Pharmacogenetics and Genomics Jg. 20 (2010) Nr. 8, S. 476 - 484
    Online Volltext: dx.doi.org/
  • El Hindy, Nicolai; Adamzik, Michael; Lambertz, Nicole; Bachmann, Hagen Sjard; Worm, Karl; Egensperger, Rupert; Frey, Ulrich; Asgari, Siamak; Sure, Ulrich; Siffert, Winfried; Sandalcioglu, Erol
    Association of the GNB3 825T-allele with better survival in patients with glioblastoma multiforme
    In: Journal of Cancer Research and Clinical Oncology Jg. 136 (2010) Nr. 9, S. 1423 - 1429
    Online Volltext: dx.doi.org/
  • Leineweber, Kirsten; Frey, Ulrich; Tenderich, Gero; Toliat, Mohammad Reza; Zittermann, Armin; Nürnberg, Peter; Körfer, Reiner; Siffert, Winfried; Heusch, Gerd
    The Arg16Gly-β2-adrenoceptor single nucleotide polymorphism : exercise capacity and survival in patients with end-stage heart failure
    In: Naunyn-Schmiedeberg's Archives of Pharmacology Jg. 382 (2010) Nr. 4, S. 357 - 365
    Online Volltext: dx.doi.org/
  • Bachmann, Hagen Sjard; Novotny, Jürgen; Sixt, Stephan Urs; Liebisch, Peter; Frey, Ulrich; Dührsen, Ulrich; Siffert, Winfried; Nückel, Holger
    The G-Allele of the PSMA6-8C>G polymorphism is associated with poor outcome in multiple myeloma independently of circulating proteasome serum levels
    In: European Journal of Haematology Jg. 85 (2010) Nr. 2, S. 108 - 113
    Online Volltext: dx.doi.org/
  • Frey, Ulrich; Hauner, Hans; Jöckel, Karl-Heinz; Manthey, Iris; Brockmeyer, Norbert; Siffert, Winfried
    A novel promoter polymorphism in the human gene GNAS affects binding of transcription factor upstream stimulatory factor 1, Gαs protein expression and body weight regulation
    In: Pharmacogenetics and Genomics Jg. 18 (2008) Nr. 2, S. 141 - 151
    Online Volltext: dx.doi.org/
  • Adamzik, Michael; Frey, Ulrich; Bitzer, Kathrin; Jakob, Heinz G.; Baba, Hideo Andreas; Schmieder, Roland E.; Schneider, Markus P.; Heusch, Gerd; Peters, Jürgen; Siffert, Winfried
    A novel-1364A/C aquaporin 5 gene promoter polymorphism influences the responses to salt loading of the renin-angiotensin-aldosterone system and of blood pressure in young healthy men
    In: Basic Research in Cardiology Jg. 103 (2008) Nr. 6, S. 598 - 610
    Online Volltext: dx.doi.org/
  • Lehnerdt, Götz; Franz, Peter; Bankfalvi, Agnes; Grehl, Sara; Jahnke, Klaus; Lang, Stephan; Schmid, Kurt Werner; Siffert, Winfried; Frey, Ulrich
    Association study of the G-protein β3 subunit C825T polymorphism with disease progression an overall survival in patients with head and neck squamous cell carcinoma
    In: Cancer Epidemiology, Biomarkers & Prevention Jg. 17 (2008) Nr. 11, S. 3203 - 3207
    Online Volltext: dx.doi.org/ (Open Access)
  • Bockhorn, Maximilian; Fingas, Christian; Rauen, Ursula; Canbay, Aliekber; Sotiropoulos, Georgios; Frey, Ulrich; Sheu, Sien-Yi; Wohlschläger, Jeremias; Broelsch, Christoph E.; Schlaak, Jörg Friedrich
    Erythropoietin treatment improves liver regeneration and survival in rat models of extended liver resection and living donor liver transplantation
    In: Transplantation Jg. 86 (2008) Nr. 11, S. 1578 - 1585
    Online Volltext: dx.doi.org/
  • Adamzik, Michael; Frey, Ulrich; Riemann, Kathrin; Sixt, Stephan Urs; Lehmann, Nils; Siffert, Winfried; Peters, Jürgen
    Factor v Leiden mutation is associated with improved 30-day survival in patients with acute respiratory distress syndrome
    In: Critical Care Medicine Jg. 36 (2008) Nr. 6, S. 1776 - 1779
    Online Volltext: dx.doi.org/
  • Lehnerdt, Götz; Franz, Peter; Winterhoff, Sebastian M.; Bankfalvi, Agnes; Grehl, Sara; Lang, Stephan; Schmid, Kurt Werner; Siffert, Winfried; Jahnke, Klaus; Frey, Ulrich
    The GNAS1 T393C polymorphism predicts survival in patients with advanced squamous cell carcinoma of the larynx
    In: Laryngoscope Jg. 118 (2008) Nr. 12, S. 2172 - 2176
    Online Volltext: dx.doi.org/
  • Schmitz, Klaus Jürgen; Langy, Hauke; Frey, Ulrich; Sotiropoulos, Georgios; Wohlschläger, Jeremias; Reis, Henning; Takeda, Atsushi; Siffert, Winfried; Schmid, Kurt Werner; Baba, Hideo Andreas
    GNAS1 T393C polymorphism is associated with clinical course in patients with intrahepatic cholangiocarcinoma
    In: Neoplasia: An International Journal for Oncology Research Jg. 9 (2007) Nr. 2, S. 159 - 165
    Online Volltext: dx.doi.org/ (Open Access)
  • Sheu, Sien-Yi; Handke, S.; Bröcker-Preuß, Martina; Görges, Rainer; Frey, Ulrich; Ensinger, C.; Öfner, D.; Farid, N.R.; Siffert, Winfried; Schmid, Kurt Werner
    The C allele of the GNB3 C825T polymorphism of the G protein β3-subunit is associated with an increased risk for the development of oncocytic thyroid tumours
    In: The Journal of Pathology Jg. 211 (2007) Nr. 1, S. 60 - 66
    Online Volltext: dx.doi.org/
  • Otterbach, Friedrich; Callies, Rainer; Frey, Ulrich; Schmitz, Klaus Jürgen; Wreczycki, Christof; Kimmig, Rainer; Siffert, Winfried; Schmid, Kurt Werner
    The T393C polymorphism in the gene GNAS1 of G protein is associated with survival of patients with invasive breast carcinoma
    In: Breast Cancer Research and Treatment Jg. 105 (2007) Nr. 3, S. 311 - 317
    Online Volltext: dx.doi.org/
  • Frey, Ulrich; Lümmen, Gerd; Jäger, Tobias; Jöckel, Karl-Heinz; Schmid, Kurt Werner; Rübben, Herbert; Müller, Norbert; Siffert, Winfried; Eisenhardt, Andreas
    The GNAS1 T393C polymorphism predicts survival in patients with clear cell renal cell carcinoma
    In: Clinical Cancer Research Jg. 12 (2006) Nr. 3, S. 759 - 763
    Online Volltext: dx.doi.org/ (Open Access)
  • Frey, Ulrich; Alakus, Hakan; Wohlschläger, Jeremias; Schmitz, Klaus Jürgen; Winde, Günther; Van Calker, Hans G.; Jöckel, Karl-Heinz; Siffert, Winfried; Schmid, Kurt Werner
    GNAS1 T393C polymorphism and survival in patients with sporadic colorectal cancer
    In: Clinical Cancer Research Jg. 11 (2005) Nr. 14, S. 5071 - 5077
    Online Volltext: dx.doi.org/ (Open Access)
  • Frey, Ulrich; Eisenhardt, Andreas; Lümmen, Gerd; Rübben, Herbert; Jöckel, Karl-Heinz; Schmid, Kurt Werner; Siffert, Winfried
    The T393C polymorphism of the Gαs gene (GNAS1) is a novel prognostic marker in bladder cancer
    In: Cancer Epidemiology, Biomarkers & Prevention Jg. 14 (2005) Nr. 4, S. 871 - 877
    Online Volltext: dx.doi.org/ (Open Access)
  • Frey, Ulrich; Nückel, Holger; Dobrev, Dobromir; Manthey, Iris; Sandalcioglu, Erol; Eisenhardt, Andreas; Worm, Karl; Hauner, Hans; Siffert, Winfried
    Quantification of G protein Gαs subunit splice variants in different human tissues and cells using pyrosequencing
    In: Gene Expression Jg. 12 (2004) Nr. 2, S. 69 - 81
    Online Volltext: dx.doi.org/ (Open Access)

    • Abstracts

  • Kapp, Johanna; Ochsenfarth, Crista; Switala, Magdalena; Frey, Ulrich; Sellmann, Ludger; Dürig, Jan; Horn, Peter; Dührsen, Ulrich; Rebmann, Vera; Nuckel, Holger
    Association of HLA-G Haplotype Risk Model with Treatment Free Survival In Chronic Lymphocytic Leukemia Patients
    In: Blood Jg. 116 (2010) Nr. 21, S. 1002 - 1003
    Online Volltext: dx.doi.org/
  • Kapp, Johanna; Ochsenfarth, Crista; Switala, Magdalena; Frey, Ulrich; Sellmann, Ludger; Dürig, Jan; Horn, Peter; Dührsen, Ulrich; Rebmann, Vera; Nückel, Holger;
    Association of HLA-G haplotype risk model with treatment free survival in chronic lymphocytic leukemia patients
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie, Berlin, Oktober 2010,
    In: Onkologie Jg. 33 (2010) Nr. Suppl. 6, S. 45
    Online Volltext: dx.doi.org/
  • Klenke, Stefanie; Frey, Ulrich; Nürnberger, Jens; Erbel, Raimund; Siffert, Winfried; Naber, Christoph;
    The functional GNAQ promoter polymorphism TT(-695/-694) GC is associated with increased cardiac output in healthy subjects and patients with coronary artery disease
    51th Annual Meeting Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie Mainz, March 23 – 25, 2010,
    In: Naunyn-Schmiedeberg's Archives of Pharmacology Jg. 381 (2010) Nr. Suppl. 1, S. 87
    Online Volltext: dx.doi.org/

    • Bücher/Sammelwerke/Tagungsbände

  • Frey, Ulrich
    Auswirkung funktionell wirksamer Polymoriphismen im β- adrenergen Signaltransduktionsweg auf Gen- und Proteinexpression sowie perioperative Hämodynamik, Myokardschädigung und Prognose
    Duisburg, Essen (2011) 1 CD-ROM