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PD Dr. rer. nat. Annette Kaiser

Funktionen

  • ---, Institut für Pharmakologie

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Makhoba, Xolani H.; Ragno, Rino; Kaiser, Annette; Agostinelli, Enzo
    An Undefined Interaction between Polyamines and Heat Shock Proteins Leads to Cellular Protection in Plasmodium falciparum and Proliferating Cells in Various Organisms
    In: Molecules: A Journal of Synthetic Chemistry and Natural Product Chemistry Jg. 28 (2023) Nr. 4, 1686
    Online Volltext: dx.doi.org/ (Open Access)
  • Kaiser, Annette
    The Role of Spermidine and Its Key Metabolites in Important, Pathogenic Human Viruses and in Parasitic Infections Caused by Plasmodium falciparum and Trypanosoma brucei
    In: Biomolecules Jg. 13 (2023) Nr. 5, 803
    Online Volltext: dx.doi.org/ (Open Access)
  • Kaiser, Annette; Agostinelli, Enzo
    Hypusinated EIF5A as a feasible drug target for Advanced Medicinal Therapies in the treatment of pathogenic parasites and therapy-resistant tumors
    In: Amino Acids Jg. 54 (2022) Nr. 4, S. 501 - 511
    Online Volltext: dx.doi.org/
  • Aroonsri, Aiyada; Wongsombat, Chayaphat; Shaw, Philip; Franke, Siegrid; Przyborski, Jude; Kaiser, Annette
    Investigation of an Allosteric Deoxyhypusine Synthase Inhibitor in P. falciparum
    In: Molecules: A Journal of Synthetic Chemistry and Natural Product Chemistry Jg. 27 (2022) Nr. 8, 2463
    Online Volltext: dx.doi.org/ (Open Access)
  • Baskal, Svetlana; Kaiser, Annette; Mels, Catharina; Kruger, Ruan; Tsikas, Dimitrios
    Specific and sensitive GC–MS analysis of hypusine, N ε-(4-amino-2-hydroxybutyl)lysine, a biomarker of hypusinated eukaryotic initiation factor eIF5A, and its application to the bi-ethnic ASOS study
    In: Amino Acids Jg. 54 (2022) Nr. 7, S. 1083 - 1099
    Online Volltext: dx.doi.org/ (Open Access)
  • Kaiser, Annette; Heiss, Kirsten; Mueller, Ann-Kristin; Fimmers, Rolf; Matthes, Jan; Njuguna, James Thujon
    Inhibition of EIF-5A prevents apoptosis in human cardiomyocytes after malaria infection
    In: Amino Acids Jg. 52 (2020) Nr. 5, S. 693 - 710
    Online Volltext: dx.doi.org/
  • Kaiser, Annette
    Druggable targets in cyclic nucleotide signaling pathways in apicomplexan parasites and kinetoplastids against disabling protozoan diseases in humans
    In: International Journal of Molecular Sciences (IJMS) Jg. 20 (2019) Nr. 1, S. 138
    Online Volltext: dx.doi.org/ (Open Access)
  • Kersting, David; Krüger, Mirko; Sattler, Julia M; Mueller, Ann-Kristin; Kaiser, Annette
    A suggested vital function for eIF-5A and dhs genes during murine malaria blood-stage infection
    In: FEBS Open Bio Jg. 6 (2016) Nr. 8, S. 860 - 872
    Online Volltext: dx.doi.org/ (Open Access)
  • Van Voorhis, Wesley C; Adams, John H; Adelfio, Roberto; Ahyong, Vida; Akabas, Myles H; Alano, Pietro; Alday, Aintzane; Alemán Resto, Yesmalie; Alsibaee, Aishah; Alzualde, Ainhoa; Andrews, Katherine T; Avery, Simon V; Avery, Vicky M; Ayong, Lawrence; Baker, Mark; Baker, Stephen; Ben Mamoun, Choukri; Bhatia, Sangeeta; Bickle, Quentin; Bounaadja, Lotfi; Bowling, Tana; Bosch, Jürgen; Boucher, Lauren E; Boyom, Fabrice F; Brea, Jose; Brennan, Marian; Burton, Audrey; Caffrey, Conor R; Camarda, Grazia; Carrasquilla, Manuela; Carter, Dee; Belen Cassera, Maria; Chih-Chien Cheng, Ken; Chindaudomsate, Worathad; Chubb, Anthony; Colon, Beatrice L; Colón-López, Daisy D; Corbett, Yolanda; Crowther, Gregory J; Cowan, Noemi; D'Alessandro, Sarah; Le Dang, Na; Delves, Michael; DeRisi, Joseph L; Du, Alan Y; Duffy, Sandra; Abd El-Salam El-Sayed, Shimaa; Ferdig, Michael T; Fernández Robledo, José A; Fidock, David A; Florent, Isabelle; Fokou, Patrick V T; Galstian, Ani; Gamo, Francisco Javier; Gokool, Suzanne; Gold, Ben; Golub, Todd; Goldgof, Gregory M; Guha, Rajarshi; Guiguemde, W Armand; Gural, Nil; Guy, R Kiplin; Hansen, Michael A E; Hanson, Kirsten K; Hemphill, Andrew; Hooft van Huijsduijnen, Rob; Horii, Takaaki; Horrocks, Paul; Hughes, Tyler B; Huston, Christopher; Igarashi, Ikuo; Ingram-Sieber, Katrin; Itoe, Maurice A; Jadhav, Ajit; Naranuntarat Jensen, Amornrat; Jensen, Laran T; Jiang, Rays H Y; Kaiser, Annette; Keiser, Jennifer; Ketas, Thomas; Kicka, Sebastien; Kim, Sunyoung; Kirk, Kiaran; Kumar, Vidya P; Kyle, Dennis E; Lafuente, Maria Jose; Landfear, Scott; Lee, Nathan; Lee, Sukjun; Lehane, Adele M; Li, Fengwu; Little, David; Liu, Liqiong; Llinás, Manuel; Loza, Maria I; Lubar, Aristea; Lucantoni, Leonardo; Lucet, Isabelle; Maes, Louis; Mancama, Dalu; Mansour, Nuha R; March, Sandra; McGowan, Sheena; Medina Vera, Iset; Meister, Stephan; Mercer, Luke; Mestres, Jordi; Mfopa, Alvine N; Misra, Raj N; Moon, Seunghyun; Moore, John P; Morais Rodrigues da Costa, Francielly; Müller, Joachim; Muriana, Arantza; Nakazawa Hewitt, Stephen; Nare, Bakela; Nathan, Carl; Narraidoo, Nathalie; Nawaratna, Sujeevi; Ojo, Kayode K; Ortiz, Diana; Panic, Gordana; Papadatos, George; Parapini, Silvia; Patra, Kailash; Pham, Ngoc; Prats, Sarah; Plouffe, David M; Poulsen, Sally-Ann; Pradhan, Anupam; Quevedo, Celia; Quinn, Ronald J; Rice, Christopher A; Abdo Rizk, Mohamed; Ruecker, Andrea; St Onge, Robert; Salgado Ferreira, Rafaela; Samra, Jasmeet; Robinett, Natalie G; Schlecht, Ulrich; Schmitt, Marjorie; Silva Villela, Filipe; Silvestrini, Francesco; Sinden, Robert; Smith, Dennis A; Soldati, Thierry; Spitzmüller, Andreas; Stamm, Serge Maximilian; Sullivan, David J; Sullivan, William; Suresh, Sundari; Suzuki, Brian M; Suzuki, Yo; Swamidass, S Joshua; Taramelli, Donatella; Tchokouaha, Lauve R Y; Theron, Anjo; Thomas, David; Tonissen, Kathryn F; Townson, Simon; Tripathi, Abhai K; Trofimov, Valentin; Udenze, Kenneth O; Ullah, Imran; Vallieres, Cindy; Vigil, Edgar; Vinetz, Joseph M; Voong Vinh, Phat; Vu, Hoan; Watanabe, Nao-Aki; Weatherby, Kate; White, Pamela M; Wilks, Andrew F; Winzeler, Elizabeth A; Wojcik, Edward; Wree, Melanie; Wu, Wesley; Yokoyama, Naoaki; Zollo, Paul H A; Abla, Nada; Blasco, Benjamin; Burrows, Jeremy; Laleu, Benoît; Leroy, Didier; Spangenberg, Thomas; Wells, Timothy; Willis, Paul A
    Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond
    In: PLoS Pathogens Jg. 12 (2016) Nr. 7, S. e1005763
    Online Volltext: dx.doi.org/ (Open Access)
  • Kaiser, Annette; Krüger, Mirko; Kersting, David; Przyborski, Jude; Langer, Barbara
    A Putative Non-Canonical Ras-Like GTPase from P. falciparum : Chemical Properties and Characterization of the Protein
    In: PLoS ONE Jg. 10 (2015) Nr. 11, S. e0140994
    Online Volltext: dx.doi.org/ (Open Access)
  • Koschitzky, Imke von; Gerhardt, Heike; Lämmerhofer, Michael; Kohout, Michal; Gehringer, Matthias; Laufer, Stefan; Pink, Mario; Schmitz-Spanke, Simone; Strube, Christina; Kaiser, Annette
    New insights into novel inhibitors against deoxyhypusine hydroxylase from plasmodium falciparum : compounds with an iron chelating potential
    In: Amino Acids Jg. 47 (2015) Nr. 6, S. 1155 - 1166
    Online Volltext: dx.doi.org/
  • Koschitzky, Imke von; Kaiser, Annette
    Erratum to: Chemical profiling of deoxyhypusine hydroxylase inhibitors for antimalarial therapy
    In: Amino Acids Jg. 46 (2014) Nr. 3, S. 643
    Online Volltext: dx.doi.org/
  • Mueller, Ann-Kristin; Hammerschmidt-Kamper, Christiane; Kaiser, Annette
    RNAi in Plasmodium
    In: Current Pharmaceutical Design Jg. 20 (2014) Nr. 2, S. 278 - 283
    Online Volltext: dx.doi.org/
  • Njuguna, James T.; Koschitzky, Imke von; Gerhardt, Heike; Lämmerhofer, Michael; Choucry, Ali; Pink, Mario; Schmitz-Spahnke, Simone; Bakheit, Mohammed A.; Strube, Christina; Kaiser, Annette
    Target evaluation of deoxyhypusine synthase from Theileria parva the neglected animal parasite and its relationship to Plasmodium
    In: Bioorganic and Medicinal Chemistry Jg. 22 (2014) Nr. 15, S. 4338 - 4346
    Online Volltext: dx.doi.org/
  • Niemand, Jandeli; Burger, Pieter; Verlinden, Bianca K.; Reader, Janette; Joubert, Annie M.; Kaiser, Annette; Louw, Abraham I.; Kirk, Kiaran; Phanstiel IV, Otto; Birkholtz, Lyn-Marie
    Anthracene-polyamine conjugates inhibit in vitro proliferation of intraerythrocytic plasmodium falciparum parasites
    In: Antimicrobial Agents and Chemotherapy Jg. 57 (2013) Nr. 6, S. 2874 - 2877
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • von Koschitzky, I.; Kaiser, Annette
    Chemical profiling of deoxyhypusine hydroxylase inhibitors for antimalarial therapy
    In: Amino Acids Jg. 45 (2013) Nr. 5, S. 1047 - 1053
    Online Volltext: dx.doi.org/
  • Atemnkeng, Veronika Anyigoh; Pink, Mario; Schmitz-Spanke, Simone; Wu, Xian-Jun; Dong, Liang-Liang; Zhao, Kai-Hong; May, Caroline; Laufer, Stefan; Langer, Barbara; Kaiser, Annette
    Deoxyhypusine Hydroxylase from Plasmodium vivax, the Neglected Human Malaria Parasite: Molecular Cloning, Expression and Specific Inhibition by the 5-LOX Inhibitor Zileuton
    In: PLoS ONE Jg. 8 (2013) Nr. 3, S. e58318
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Kaiser, Annette; Khomutov, A. R.; Simonian, A.; Agostinelli, E.
    A rapid and robust assay for the determination of the amino acid hypusine as a possible biomarker for a high-throughput screening of antimalarials and for the diagnosis and therapy of different diseases
    In: Amino Acids Jg. 42 (2012) Nr. 5, S. 1651 - 1659
    Online Volltext: dx.doi.org/
  • Schwentke, Andreas; Krepstakies, Marcel; Mueller, Ann-Kristin; Hammerschmidt-Kamper, Christiane; Motaal, Basma A.; Bernhard, Tina; Hauber, Joachim; Kaiser, Annette
    In vitro and in vivo silencing of plasmodial dhs and eIf-5a genes in a putative, non-canonical RNAi-related pathway
    In: BMC Microbiology Jg. 12 (2012) S. 107
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Bouchaud, O.; Mühlberger, N.; Parola, P.; Calleri, G.; Matteelli, A.; Peyerl-Hoffmann, G.; Méchaï, F.; Gautret, P.; Clerinx, J.; Kremsner, P. G.; Jelinek, T.; Kaiser, Annette; Beltrame, A.; Schmid, M. L.; Kern, P.; Probst, M.; Bartoloni, A.; Weinke, T.; Grobusch, M. P.
    Therapy of uncomplicated falciparum malaria in Europe : MALTHER - a prospective observational multicentre study
    In: Malaria Journal Jg. 11 (2012) S. 212
    Online Volltext: dx.doi.org/
  • Kaiser, Annette
    Translational control of eIF5A in various diseases
    In: Amino Acids Jg. 42 (2012) Nr. 2-3, S. 679 - 684
    Online Volltext: dx.doi.org/

    • Vorworte / Nachworte

  • Kaiser, Annette; Doerig, Christian
    Editorial: Heading Against Parasitic Resistance : A Screen for Next Generation Drugs Against Targets of cAMP- or cGMP-regulated Pathways
    In: Frontiers in Microbiology Jg. 12 (2021) 727978
    Online Volltext: dx.doi.org/ (Open Access)

    • Abstracts

  • Geismar, Dirk; Quamhiyeh, S.; Kaiser, Annette; Pottgen, C.; Farr, Jonathan; Stuschke, Martin;
    Protonentherapie bei der Bestrahlung von Patienten mit Prostatakarzinom unter Einschluss des pelvinen Lymphabflusses : eine Planvergleichsstudie
    17. Jahreskongress der Deutschen Gesellschaft für Radioonkologie Radioonkologie Wiesbaden, 2. bis 5. Juni 2011,
    In: Strahlentherapie und Onkologie Jg. 187 (2011) Nr. Suppl. 1, S. 61 - 62
    Online Volltext: dx.doi.org/