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Fakultät Biologie
Anschrift
Universitätsstr 2
45117 Essen
45117 Essen
Raum
S05 R02 H87
Telefon
Telefax
E-Mail
Funktionen
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Gruppe der Professorinnen und Professoren, Fakultätsrat Biologie
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Professor/in, Molekulare Genetik II
Aktuelle Veranstaltungen
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2024 WS
- Übungen zur Mikrobiologie und Genetik für medizinische Biologen
- Allgemeine Methoden (Bachelor Bio)
- Allgemeine Methoden in der Molekularbiologie
- Übungen zur Genetik (BSc Biologie, BSc Molekularbiologie, BSc AquaBio)
- Einführung in die Genetik
- Seminar zur Genetik
- Group Meeting
- Molekulare Genetik f. Molbio (VO u. PR)
Vergangene Veranstaltungen (max. 10)
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2024 SS
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2023 WS
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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TopBP1 utilises a bipartite GINS binding mode to support genome replicationIn: Nature Communications Jg. 15 (2024) Nr. 1, 1797Online Volltext: dx.doi.org/; Online Volltext: dx.doi.org/ (Open Access)
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Cell-type specificity of the human mutation landscape with respect to DNA replication dynamicsIn: Cell Genomics Jg. 3 (2023) Nr. 6, 100315Online Volltext: dx.doi.org/ (Open Access)
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Refining the domain architecture model of the replication origin firing factor Treslin/TICRRIn: Life Science Alliance Jg. 5 (2022) Nr. 5, e202101088Online Volltext: dx.doi.org/ (Open Access)
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The Role of MTBP as a Replication Origin Firing FactorIn: Biology Jg. 11 (2022) Nr. 6, 827Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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The TRESLIN-MTBP complex couples completion of DNA replication with S/G2 transitionIn: Molecular Cell Jg. 82 (2022) Nr. 18, S. 3350 - 3365.e7Online Volltext: dx.doi.org/ (Open Access)
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MTBP phosphorylation controls DNA replication origin firingIn: Scientific Reports Jg. 11 (2021) Nr. 1, 4242Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Origin firing regulations to control genome replication timingIn: Genes Jg. 10 (2019) Nr. 3, S. 199Online Volltext: dx.doi.org/ (Open Access)
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The Cdk8/19-cyclin C transcription regulator functions in genome replication through metazoan Sld7In: PLoS Biology Jg. 17 (2019) Nr. 1, e2006767Online Volltext: dx.doi.org/ (Open Access)
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BRCT domains of the DNA damage checkpoint proteins TOPBP1/Rad4 display distinct specificities for phosphopeptide ligandsIn: eLife Jg. 7 (2018) S. e39979Online Volltext: dx.doi.org/ (Open Access)
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Targeting of the Fun30 nucleosome remodeller by the Dpb11 scaffold facilitates cell cycle-regulated DNA end resectionIn: eLife (2017) Nr. 6, S. e21687Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Identification of a Heteromeric Complex That Promotes DNA Replication Origin Firing in Human CellsIn: Science Jg. 340 (2013) Nr. 6135, S. 981 - 984Online Volltext: dx.doi.org/
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Activation of the replicative DNA helicase : breaking up is hard to doIn: Current Opinion in Cell Biology Jg. 24 (2012) Nr. 3, S. 423 - 430Online Volltext: dx.doi.org/
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Cleavage of cohesin rings coordinates the separation of centrioles and chromatidsIn: Nature Cell Biology Jg. 13 (2011) Nr. 8, S. 966 - 972Online Volltext: dx.doi.org/
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Regulation of DNA Replication through Sld3-Dpb11 Interaction Is Conserved from Yeast to HumansIn: Current Biology Jg. 21 (2011) Nr. 13, S. 1152 - 1157Online Volltext: dx.doi.org/
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Phosphorylation-dependent Binding of Cyclin B1 to a Cdc6-like Domain of Human SeparaseIn: The Journal of Biological Chemistry (JBC) Jg. 283 (2008) Nr. 2, S. 816 - 823Online Volltext: dx.doi.org/
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Anaphase Topsy-Turvy : Cdk1 a Securin, Separase a CKIIn: Cell Cycle Jg. 5 (2006) Nr. 1, S. 11 - 13Online Volltext: dx.doi.org/
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Essential CDK1-inhibitory role for separase during meiosis I in vertebrate oocytesIn: Nature Cell Biology Jg. 8 (2006) Nr. 9, S. 1035 - 1037Online Volltext: dx.doi.org/
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Mutual inhibition of separase and Cdk1 by two-step complex formationIn: Molecular Cell Jg. 19 (2005) Nr. 1, S. 135 - 141Online Volltext: dx.doi.org/ (Open Access)
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Rephrasing anaphase : separase FEARs shugoshinIn: Chromosoma Jg. 113 (2005) Nr. 8, S. 409 - 417Online Volltext: dx.doi.org/
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Regulation of the Initiation of DNA Replication upon DNA Damage in EukaryotesIn: The Initiation of DNA Replication in Eukaryotes / Kaplan, Daniel L. (Hrsg.) 2016, S. 443 - 460Online Volltext: dx.doi.org/
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Roles of Sld2, Sld3, and Dpb11 in Replication InitiationIn: The Initiation of DNA Replication in Eukaryotes / Kaplan, Daniel L. (Hrsg.) 2016, S. 297 - 318Online Volltext: dx.doi.org/