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Universitätsstr. 2-5
45141 Essen
45141 Essen
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S03 S00 A35
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Funktionen
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Wiss. Mitarbeiterinnen/Mitarbeiter, Strukturelle und Medizinische Biochemie
Aktuelle Veranstaltungen
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2024 WS
- Struktur und Funktion der Zelle (LA Ba)
- MedBio Lab Rotation
- Grundlagen der Biotechnologie (LA Ba); Platzvergabe: 3 Präferenzen angeben
- Analytikmethoden zur Struktur von Molekülen
- Physik für Biologen (Bio B.Sc. und Aquatische Bio B.Sc., Molekularbiologie)
- VO Struktur und Funktion von Biopolymeren
- Biophysikalische Chemie
Vergangene Veranstaltungen (max. 10)
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2024 SS
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2023 WS
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2023 SS
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2022 WS
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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Functional Linkers Support Targeting of Multivalent Tweezers to Taspase1In: Chemistry - A European Journal Jg. 30 (2024) Nr. 56, e202401542Online Volltext: dx.doi.org/ (Open Access)
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High resolution analysis of proteolytic substrate processingIn: The Journal of Biological Chemistry (JBC) Jg. 300 (2024) Nr. 11, 107812Online Volltext: dx.doi.org/ (Open Access)
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Increased Cytotoxicity of Bimetallic Ultrasmall Silver–Platinum Nanoparticles (2 nm) on Cells and Bacteria in Comparison to Silver Nanoparticles of the Same SizeIn: Materials Jg. 17 (2024) Nr. 15, 3702Online Volltext: dx.doi.org/ (Open Access)
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Possibilities and limitations of solution-state NMR spectroscopy to analyze the ligand shell of ultrasmall metal nanoparticlesIn: Nanoscale Advances Jg. 6 (2024) Nr. 13, S. 3285 - 3298Online Volltext: dx.doi.org/ (Open Access)
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Rational correction of pathogenic conformational defects in HTRA1In: Nature Communications Jg. 15 (2024) Nr. 1, 5944Online Volltext: dx.doi.org/ (Open Access)
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The Molecular Footprint of Peptides on the Surface of Ultrasmall Gold Nanoparticles (2 nm) Is Governed by Steric DemandIn: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry Jg. 128 (2024) Nr. 17, S. 4266 - 4281Online Volltext: dx.doi.org/
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Multivalent Molecular Tweezers Disrupt the Essential NDC80 Interaction with MicrotubulesIn: Journal of the American Chemical Society: JACS Jg. 145 (2023) Nr. 28, S. 15251 - 15264Online Volltext: dx.doi.org/
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Potentiating Tweezer Affinity to a Protein Interface with Sequence-Defined Macromolecules on NanoparticlesIn: Biomacromolecules Jg. 24 (2023) Nr. 8, S. 3666 - 3679Online Volltext: dx.doi.org/
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The UBX domain in UBXD1 organizes ubiquitin binding at the C-terminus of the VCP/p97 AAA-ATPaseIn: Nature Communications Jg. 14 (2023) Nr. 1, 3258Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Ultrastructure and Surface Composition of Glutathione-Terminated Ultrasmall Silver, Gold, Platinum, and Alloyed Silver-Platinum Nanoparticles (2 nm)In: Inorganic Chemistry Jg. 62 (2023) Nr. 42, S. 17470 - 17485Online Volltext: dx.doi.org/
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Dual activity inhibition of threonine aspartase 1 by a single bisphosphate ligandIn: RSC Advances Jg. 12 (2022) Nr. 53, S. 34176 - 34184Online Volltext: dx.doi.org/ (Open Access)
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Recognition of a Flexible Protein Loop in Taspase 1 by Multivalent Supramolecular TweezersIn: Biomacromolecules Jg. 23 (2022) Nr. 11, S. 4504 - 4518Online Volltext: dx.doi.org/
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Water-Based Synthesis of Ultrasmall Nanoparticles of Platinum Group Metal Oxides (1.8 nm)In: Inorganic Chemistry Jg. 61 (2022) Nr. 12, S. 5133 - 5147Online Volltext: dx.doi.org/
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Metal-Ligand Interface and Internal Structure of Ultrasmall Silver Nanoparticles (2 nm)In: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry Jg. 125 (2021) Nr. 21, S. 5645 - 5659Online Volltext: dx.doi.org/
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New tools to probe the protein surface : Ultrasmall gold nanoparticles carry amino acid bindersIn: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry Jg. 125 (2021) Nr. 1, S. 115 - 127Online Volltext: dx.doi.org/ (Open Access)
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Peptide-Conjugated Ultrasmall Gold Nanoparticles (2 nm) for Selective Protein TargetingIn: ACS Applied Bio Materials Jg. 4 (2021) Nr. 1, S. 945 - 965Online Volltext: dx.doi.org/ (Open Access)
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Specific inhibition of the Survivin–CRM1 interaction by peptide-modified molecular tweezersIn: Nature Communications Jg. 12 (2021) Nr. 1, S. 1505Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Targeting the Surface of the Protein 14-3-3 by Ultrasmall (1.5 nm) Gold Nanoparticles Carrying the Specific Peptide CRafIn: ChemBioChem Jg. 22 (2021) Nr. 8, S. 1456 - 1463Online Volltext: dx.doi.org/ (Open Access)
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Functional Disruption of the Cancer-Relevant Interaction between Survivin and Histone H3 with a Guanidiniocarbonyl Pyrrole LigandIn: Angewandte Chemie International Edition Jg. 59 (2020) Nr. 14, S. 5567 - 5571Online Volltext: dx.doi.org/ (Open Access)
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NMR Spectroscopy of supramolecular chemistry on protein surfacesIn: Beilstein Journal of Organic Chemistry Jg. 16 (2020) S. 2505 - 2522Online Volltext: dx.doi.org/ (Open Access)
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Click chemistry on the surface of ultrasmall gold nanoparticles (2 nm) for covalent ligand attachment followed by nmr spectroscopyIn: Langmuir Jg. 35 (2019) Nr. 22, S. 7191 - 7204Online Volltext: dx.doi.org/
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Multivalent Ligands with Tailor-Made Anion Binding Motif as Stabilizers of Protein–Protein InteractionsIn: ChemBioChem Jg. 20 (2019) Nr. 23, S. 2921 - 2926Online Volltext: dx.doi.org/
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Solution NMR Spectroscopy with Isotope-Labeled Cysteine (¹³C and ¹⁵N) Reveals the Surface Structure of l -Cysteine-Coated Ultrasmall Gold Nanoparticles (1.8 nm)In: Langmuir Jg. 35 (2019) Nr. 3, S. 767 - 778Online Volltext: dx.doi.org/
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Structure of the PUB Domain from Ubiquitin Regulatory X Domain Protein 1 (UBXD1) and Its Interaction with the p97 AAA+ ATPaseIn: Biomolecules Jg. 9 (2019) Nr. 12, 876Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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An NMR Method To Pinpoint Supramolecular Ligand Binding to Basic Residues on ProteinsIn: Angewandte Chemie International Edition Jg. 56 (2017) Nr. 46, S. 14758 - 14762Online Volltext: dx.doi.org/
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Molecular tweezers target a protein-protein interface and thereby modulate complex formationIn: Chemical Communications: ChemComm Jg. 52 (2016) Nr. 98, S. 14141 - 14144Online Volltext: dx.doi.org/ (Open Access)
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Structural Characterization of the Loop at the Alpha-Subunit C-Terminus of the Mixed Lineage Leukemia Protein Activating Protease Taspase1In: PLoS ONE Jg. 11 (2016) Nr. 3, S. e0151431Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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The acidic domain is a unique structural feature of the splicing factor SYNCRIPIn: Protein Science Jg. 25 (2016) Nr. 8, S. 1545 - 1550Online Volltext: dx.doi.org/ (Open Access)
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Reversibly locked thionucleobase pairs in DNA to study base flipping enzymesIn: Beilstein Journal of Organic Chemistry Jg. 10 (2014) S. 2293 - 2306Online Volltext: dx.doi.org/ (Open Access)