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Klinik für Kinderheilkunde, AG Experimentelle perinatale Neurowissenschaften
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Essen
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Mitglied, Zentrum für Medizinische Biotechnologie
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Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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A report on the International Society for Cell & Gene Therapy 2022 Scientific Signature Series, “Therapeutic advances with native and engineered human extracellular vesicles”In: Cytotherapy Jg. 25 (2023) Nr. 8, S. 810 - 814Online Volltext: dx.doi.org/
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Extracellular vesicles from immortalized mesenchymal stromal cells protect against neonatal hypoxic-ischemic brain injuryIn: Inflammation and Regeneration Jg. 43 (2023) Nr. 1, 24Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Hypothermia combined with extracellular vesicles from clonally expanded immortalized mesenchymal stromal cells improves neurodevelopmental impairment in neonatal hypoxic-ischemic brain injuryIn: Journal of Neuroinflammation Jg. 20 (2023) Nr. 1, 280Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Neuropilin-1 identifies a subset of highly activated CD8⁺ T cells during parasitic and viral infectionsIn: PLoS Pathogens Jg. 19 (2023) Nr. 11, e1011837Online Volltext: dx.doi.org/ (Open Access)
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Perinatal Hyperoxia and Developmental Consequences on the Lung-Brain AxisIn: Oxidative Medicine and Cellular Longevity (2022) 5784146Online Volltext: dx.doi.org/ (Open Access)
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Peripheral immune cells and perinatal brain injury : A double-edged sword?In: Pediatric Research Jg. 91 (2022) Nr. 2, S. 392 - 403Online Volltext: dx.doi.org/ (Open Access)
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Postischemic Neuroprotection Associated With Anti-Inflammatory Effects by Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles in Aged MiceIn: Stroke Jg. 53 (2022) Nr. 1, S. E14 - E18Online Volltext: dx.doi.org/ (Open Access)
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Regulatory T Cells Contribute to Sexual Dimorphism in Neonatal Hypoxic-Ischemic Brain InjuryIn: Stroke Jg. 53 (2022) Nr. 2, S. 381 - 390Online Volltext: dx.doi.org/ (Open Access)
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Hypothermia modulates myeloid cell polarization in neonatal hypoxic–ischemic brain injuryIn: Journal of Neuroinflammation Jg. 18 (2021) Nr. 1, 266Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Neutrophil dynamics, plasticity and function in acute neurodegeneration following neonatal hypoxia-ischemiaIn: Brain, Behavior and Immunity Jg. 92 (2021) S. 234 - 244Online Volltext: dx.doi.org/ (Open Access)
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Involvement of CXCL1/CXCR2 During Microglia Activation Following Inflammation-Sensitized Hypoxic-Ischemic Brain Injury in Neonatal RatsIn: Frontiers in Neurology Jg. 11 (2020) S. 540878Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Mesenchymal Stromal Cell-Derived Extracellular Vesicles Reduce Neuroinflammation, Promote Neural Cell Proliferation and Improve Oligodendrocyte Maturation in Neonatal Hypoxic-Ischemic Brain InjuryIn: Frontiers in Cellular Neuroscience Jg. 14 (2020) S. 601176Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Repetitive Erythropoietin Treatment Improves Long-Term Neurocognitive Outcome by Attenuating Hyperoxia-Induced Hypomyelination in the Developing BrainIn: Frontiers in Neurology Jg. 11 (2020) S. 804Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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White Matter Brain Development after Exposure to Circulating Cell-Free Hemoglobin and Hyperoxia in a Rat Pup ModelIn: Developmental Neuroscience Jg. 41 (2020) Nr. 3-4, S. 234 - 246Online Volltext: dx.doi.org/ (Open Access)
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Adverse neuropsychiatric development following perinatal brain injury : from a preclinical perspectiveIn: Pediatric Research Jg. 85 (2019) Nr. 2, S. 198 - 215Online Volltext: dx.doi.org/ (Open Access)
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Detrimental Impact of Energy Drink Compounds on Developing Oligodendrocytes and NeuronsIn: Cells Jg. 8 (2019) Nr. 11, S. 1381Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Early pro-inflammatory microglia activation after inflammation-sensitized hypoxic-ischemic brain injury in neonatal ratsIn: Frontiers in Cellular Neuroscience Jg. 13 (2019) S. 237Online Volltext: dx.doi.org/ (Open Access)
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Zbtb20 Regulates Developmental Neurogenesis in the Olfactory Bulb and Gliogenesis After Adult Brain InjuryIn: Molecular Neurobiology Jg. 56 (2019) Nr. 1, S. 567 - 582Online Volltext: dx.doi.org/
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Interaction between hypothermia and delayed mesenchymal stem cell therapy in neonatal hypoxic-ischemic brain injuryIn: Brain, Behavior and Immunity Jg. 70 (2018) S. 118 - 130Online Volltext: dx.doi.org/ (Open Access)
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Peripheral T cell depletion by FTY720 exacerbates hypoxic-ischemic brain injury in neonatal miceIn: Frontiers in Immunology Jg. 9 (2018) S. 1696Online Volltext: dx.doi.org/ (Open Access)
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Protection of oligodendrocytes through neuronal overexpression of the small GTPase ras in hyperoxia-induced neonatal brain injuryIn: Frontiers in Neurology Jg. 9 (2018) S. 175Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Dendritic cells tip the balance towards induction of regulatory T cells upon priming in experimental autoimmune encephalomyelitisIn: Journal of Autoimmunity Jg. 76 (2017) S. 108 - 114Online Volltext: dx.doi.org/
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Effects of Poly(ADP-Ribose) Polymerase-1 Inhibition in a Neonatal Rodent Model of Hypoxic-Ischemic InjuryIn: BioMed Research International (2017) 2924848Online Volltext: dx.doi.org/ (Open Access)
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Mesenchymal stem cell-derived extracellular vesicles ameliorate inflammation-induced preterm brain injuryIn: Brain, Behavior and Immunity Jg. 60 (2017) S. 220 - 232Online Volltext: dx.doi.org/ (Open Access)
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Sildenafil Enhances Quantity of Immature Neurons and Promotes Functional Recovery in the Developing Ischemic Mouse BrainIn: Developmental Neuroscience Jg. 39 (2017) Nr. 1-4, S. 287 - 297Online Volltext: dx.doi.org/
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Endogenous hypothermic response to hypoxia reduces brain injury : Implications for modeling hypoxic-ischemic encephalopathy and therapeutic hypothermia in neonatal miceIn: Experimental Neurology Jg. 283, Part A (2016) S. 264 - 275Online Volltext: dx.doi.org/ (Open Access)
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Erythropoietin Restores Long-Term Neurocognitive Function Involving Mechanisms of Neuronal Plasticity in a Model of Hyperoxia-Induced Preterm Brain InjuryIn: Oxidative Medicine and Cellular Longevity (2016) S. 9247493Online Volltext: dx.doi.org/ (Open Access)
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Fingolimod protects against neonatal white matter damage and long-term cognitive deficits caused by hyperoxiaIn: Brain, Behavior and Immunity Jg. 52 (2016) S. 106 - 119Online Volltext: dx.doi.org/ (Open Access)
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Extracellular Vesicles Improve Post-Stroke Neuroregeneration and Prevent Postischemic ImmunosuppressionIn: Stem Cells Translational Medicine Jg. 4 (2015) Nr. 10, S. 1131 - 1143Online Volltext: dx.doi.org/ (Open Access)
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Role of Neutrophils in Exacerbation of Brain Injury After Focal Cerebral Ischemia in Hyperlipidemic MiceIn: Stroke Jg. 46 (2015) Nr. 10, S. 2916 - 2925Online Volltext: dx.doi.org/ (Open Access)
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Tracking CNS and systemic sources of oxidative stress during the course of chronic neuroinflammationIn: Acta Neuropathologica Jg. 130 (2015) Nr. 6, S. 799 - 814Online Volltext: dx.doi.org/ (Open Access)
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Very-late-antigen-4 (VLA-4)-mediated brain invasion by neutrophils leads to interactions with microglia, increased ischemic injury and impaired behavior in experimental strokeIn: Acta Neuropathologica Jg. 129 (2015) Nr. 2, S. 259 - 277Online Volltext: dx.doi.org/
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Exacerbation of ischemic brain injury in hypercholesterolemic mice is associated with pronounced changes in peripheral and cerebral immune responsesIn: Neurobiology of Disease Jg. 62 (2014) S. 456 - 468Online Volltext: dx.doi.org/
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Inhibition of Acetylcholinesterase Modulates NMDA Receptor Antagonist Mediated Alterations in the Developing BrainIn: International Journal of Molecular Sciences (IJMS) Jg. 15 (2014) Nr. 3, S. 3784 - 3798Online Volltext: dx.doi.org/ (Open Access)
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Modulation of Dendritic Cell Immunobiology via Inhibition of 3-Hydroxy-3-Methylglutaryl-CoA (HMG-CoA) ReductaseIn: PLoS ONE Jg. 9 (2014) Nr. 7, S. e100871Online Volltext: dx.doi.org/ (Open Access)
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Neuroprotection by blocking CXCR2 after cerebral ischemia in hypercholesterolemic miceIn: Journal of Neuroimmunology Jg. 275 (2014) Nr. 1-2, S. 152 - 153Online Volltext: dx.doi.org/
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Intravascular Perfusion of Carbon Black Ink Allows Reliable Visualization of Cerebral VesselsIn: JoVE (2013) Nr. 71, S. e4374Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Parallelized TCSPC for dynamic intravital fluorescence lifetime imaging : quantifying neuronal dysfunction in neuroinflammationIn: PLoS ONE Jg. 8 (2013) Nr. 4, S. e60100Online Volltext: dx.doi.org/ (Open Access)
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The role of CD8+T cells and their local interaction with CD4+T cells in myelin oligodendrocyte glycoprotein35-55-induced experimental autoimmune encephalomyelitisIn: The Journal of Immunology (JI) Jg. 191 (2013) Nr. 10, S. 4960 - 4968Online Volltext: dx.doi.org/
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Acute peripheral and CNS immune responses in hypercholesterolemic mice after mild brain ischemiaIn: Journal of Neuroimmunology Jg. 253 (2012) Nr. 1-2, S. 99
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Intracerebroventricularly delivered VEGF promotes contralesional corticorubral plasticity after focal cerebral ischemia via mechanisms involving anti-inflammatory actionsIn: Neurobiology of Disease Jg. 45 (2012) Nr. 3, S. 1077 - 1085Online Volltext: dx.doi.org/
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Intravascular perfusion of carbon black ink allows reliable visualization of cerebral vessels in miceIn: European Journal of Neurology Jg. 19 (2012) Nr. Suppl. 1, S. 185
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The novel proteasome inhibitor BSc2118 protects against cerebral ischaemia through HIF1A accumulation and enhanced angioneurogenesisIn: Brain: A Journal of Neurology Jg. 135 (2012) Nr. 11, S. 3282 - 3297Online Volltext: dx.doi.org/
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Transduction of neural precursor cells with TAT-heat shock protein 70 chaperone : Therapeutic potential against ischemic stroke after intrastriatal and systemic transplantationIn: Stem Cells Jg. 30 (2012) Nr. 6, S. 1297 - 1310Online Volltext: dx.doi.org/
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Visualization of macroscopic cerebral vessel anatomy—A new and reliable technique in miceIn: Journal of Neuroscience Methods Jg. 204 (2012) Nr. 2, S. 249 - 253Online Volltext: dx.doi.org/
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In vivo imaging of lymphocytes in the CNS reveals different behaviour of naïve T cells in health and autoimmunityIn: Journal of Neuroinflammation Jg. 8 (2011) S. 131Online Volltext: dx.doi.org/ (Open Access)
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Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous systemIn: Nature Medicine Jg. 15 (2009) Nr. 7, S. 788 - 793Online Volltext: dx.doi.org/
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Geranylgeranylation but not GTP loading determines rho migratory function in T cellsIn: The Journal of Immunology Jg. 179 (2007) Nr. 9, S. 6024 - 6032Online Volltext: dx.doi.org/
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Clonal immortalized mesenchymal stromal cells : An ideal cell source for a reproducible and standardized production of therapeutic extracellular vesiclesIn: Cytotherapy Jg. 26 (2024) Nr. 6, S. S83Online Volltext: dx.doi.org/
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Regulatory T cells contribute to sexual dimorphism in neonatal hypoxic-ischemic brain injury
4th Congress of Joint European Neonatal Societies: Brain, Development and Imaging; 14–18 September 2021; Virtual, Online,In: Pediatric Research Jg. 90 (2021) Nr. Suppl. 1, S. 3Online Volltext: dx.doi.org/ (Open Access) -
Catch me if you can! : Novel immune escape mechanisms in melanoma metastases of the brain
45th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF) ; March 7‐10, 2018, Zürich,In: Experimental Dermatology Jg. 27 (2018) Nr. 3, S. e15Online Volltext: dx.doi.org/ (Open Access) -
Exosomes reduce brain injury in a rodent stroke model via immunomodulatory actions and stimulation of post-ischemic neuroregeneration
Joint Congress of European Neurology 31 May–3 June 2014 Istanbul, Turkey,In: Journal of Neurology Jg. 261 (2014) Nr. Suppl. 1, S. 70Online Volltext: dx.doi.org/ -
Exosomes reduce brain injury in a rodent stroke model via immunomodulatory actions and stimulation of post-ischemic neuroregeneration
Joint Congress of European Neurology, Istanbul, Turkey, May 2014,In: European Journal of Neurology Jg. 21 (2014) Nr. Suppl. 1, S. 97Online Volltext: dx.doi.org/ -
Activation of kinin receptor B1 limits encephalitogenic T-lymphocyte recruitment to the central nervous systemIn: Multiple Sclerosis Journal Jg. 15 (2009) Nr. 9, Supplement, S. S75Online Volltext: dx.doi.org/
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Neuroinflammation in der ischämischen Hirnschädigung : Chancen und Herausforderungen in der prä-klinischen Evaluation protektiver TherapieansätzeDuisburg ; Essen (2018) 1 CD-ROM
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CLONAL IMMORTALIZED MESENCHYMAL STROMAL CELLS APPEAR AS AN IDEAL CELL SOURCE FOR THE PRODUCTION OF THERAPEUTIC EXTRACELLULAR VESICLES
28th Annual ISCT Meeting; 4-7 May 2022; San Francisco, USA,In: Cytotherapy Jg. 24 (2022) Nr. 5, Supplement, S. S87Online Volltext: dx.doi.org/