Group
Group Leader
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Dr. Christoph HirschhäuserChristoph has studied Chemistry in Cologne, where he received his PhD in the group of Professor Schmalz working on bio-metal-organic chemistry. After that he went to Bristol, where he worked as a postdoc in the group of Professor Gallagher on natural product synthesis and later for AstraZeneca. In 2012 he came to Essen where he became a permanent employee (Akad. Rat.) in 2014. Room: S07 S04 C49 |
Postdocs
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Dr. Kevin BojarynKevin is a veteran of our group, who was involved in several over the years. Most recently he is working on the synthesis of Antimycins. The chiral motif of these bioactive macrolactones provide an interesting challange for classical Matteson reactions and Kevin is probing new methods develloped in our group to crack this motif. Publications: "Differentially Protected Glycols from α-Halo Boronic Esters and Lithiated Benzoates" K. Bojaryn, C. Hirschhäuser* Eur J. Org. Chem. 2024, 27, e202300953. Highlighted on the Front Cover "Total Synthesis of Resveratrone and iso-Resveratrone” S. Fritsch, N. Aldemir, J. Balszuweit, K. Bojary, J. Voskuhl, C. Hirschhäuser* ChemistryOpen 2022, 11, e202200098. Highlighted in Chemistry Views "Transition Metal Catalyst Free Synthesis of Olefins from Organoboron Derivatives" K. Bojaryn, C. Hirschhäuser*, Chemistry a European Journal, 2022, 28, e202104125. Highlighted by Frontispiece "Iterative Synthesis of Alkenes by Insertion of Lithiated Epoxides into Boronic Esters"; K. Bojaryn, S. Fritsch, C. Hirschhäuser*, Organic Letters, 2019, doi:10.1021/acs.orglett.9b00517. "Ambient-Pressure Asymmetric Preparation of S,S-DICHED, a C2-Symmetrical Director for Matteson Reactions"; K. Bojaryn, C. Hoffmann, F. R. Struth, C. Hirschhäuser*, Synlett, 2018, 29, 1092-1094. Room: S07 S04 D25 |
PhD Students
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Haemo Lee (M. Sc.)Haemo received his Master´s degree in Chemistry from the University of Hannover. After that he started to pursue a PhD in our group. Since summer 2021 he is working on the devellopment of an epi-Matteson reaction, that delivers a complementary stereochemical outcome to the venerable Matteson reaction. Such a method will be very valuable for downstream applications in iterative synthesis. Room: S07 S04 C17 |
Bachelor Students
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Matthias WeckmannMatthias explores the application of boronate homologations for the stereoselective synthesis of disubstituted binaphthol-derivatives.
Room: S07 S04 D25 |
Alumni
Postdoctoral Projects
2021 Dr. Suman Kumar Maity: Cell Specific Anti-Cancer Agents
PhD Theses
2019-2024 N. Aldemir: GCP-Lysin Dendrimers as Transfectionsvektors
2018-2023 Dr. K. Bojaryn: Convergent Coupling of Chiral Boronic Esters
2019-2022 Dr. T. Dirksmeyer: Cellspecific Transfection
2017-2022 Dr. S. Kirupakaran: Synthesis of all Aldohexoses
2019 - 2021 P. Naschenweng: Towards a Supramolecular Cocktail Bar
Master Theses
2019 S. Fritsch: Synthesis of Resveratrone and Derivatives
2018 C. Hoffmann: Towards a Convergent Synthesis of Aldohexoses
2018 K. Bojaryn: New Routes to Tetrasubstituted Alkenes
Student Research Projects
2018 – 2019 S. Fritsch: Insertion of Lithiated Epoxides into Boronic Esters
2017 – 2018 K. Bojaryn: Iterative Synthesis of Trisubstituted Alkenes
2017 C. Hoffmann: Towards a Convergent Synthesis of Aldohexoses
2015 V. Terehina: Synthesis of a Dihydroxy Dihydro Benzoic Acid
2014 – 2015 I. Stratmann: Aminoboronic Acids with Basic Character
2013 – 2016 F. R. Struth: A Matteson bases Synthesis of Cytisine
Bachelor Theses
2023 T. Gatz: Towards Chiral Catenanes from meso-Precursors
2022 N. Heger: Haloboronates for epi-Matteson Reactions
2022 M. Grimberg: Synthesis of a GCP-Zwitterion-Nopol-Conjugate
2021 G. Arago: Synthesis of Vinyl-Metal-Reagents from CH2X2
2021 Z. Ren: Coupling of Chiral Boronates with Carbenoids
2020 – 2021 D. Köhler: Exploring B-Mg-Exchange Reactions
2019 C. Vonnemann: Iterative Synthesis of Unymmetrical Stilbenes
2018 K. Kostka: Exploring new Auxiliaries for Matteson Reactions
2017 S. Fritsch: Insertion of Styrenoxide into Boronic Esters
2017 K. Helbig: Exploring Masked Pyridines for Matteson Reactions
2016 K. Bojaryn: Olefins from Boronic Esters and Carbenoids
2015 J. Balszuweit: Exploring Cyclisation by 1,2-Rearrangement
2014 – 2015 S. Lazarevic: Extraction of Cytisine from Laburnum Seeds
Video Abstracts
Differentially Protected Glycols from α-Halo Boronic Esters and Lithiated Benzoates
Total Synthesis of Resveratrone and iso-Resveratrone
Transition Metal Catalyst Free Synthesis of Olefins from Organoboron Derivatives
Iterative Synthesis of Alkenes by Insertion of Lithiated Expoxides into Boronic Esters
A Modular Approach to the Asymmetric Synthesis of Cytisine
