Professional Experience

Principal Investigator

Institute for the Research on HIV and AIDS-associated Diseases

Jan 2024-present

Essen, Germany

Postdoctoral Fellow

Institute for the Research on HIV and AIDS-associated Diseases

March 2021-Dec 2023

Essen, Germany

Doctoral Student

Vitalant Research Institut, Pillai Lab, FU Berlin

June 2017-March 2021

San Francisco, CA

Research Assistant

Vitalant Research Institut, Pillai Lab

Feb 2017-May 2021

San Francisco, CA

Self-employed Image Analyst

Bionukleo UG

Aug 2016-Feb 2017

Berlin, Germany

Master's Student

Weizmann Institute of Science, Gerst Lab

Sep 2014-May 2016

Rehovot, Israel

Research Student

Humboldt University - Molecular Biophysics

Nov 2013-Sep 2014

Berlin, Germany

Bachelor Student

Humboldt University - Molecular Biophysics

Feb 2013-Nov 2013

Berlin, Germany

Tutor

Charité University Hospital, PC Pool

Oct 2010-Dec 2013

Berlin, Germany

Education and Degrees

Dr. rer. nat. 

FU Berlin

June 2017-Sep 2021

Berlin, Germany

Master in Molecular Life Sciences

Humboldt University

Oct 2013-Sep 2016

Berlin, Germany

Bachelor in Biology

Humboldt University                                                                                                  

Oct 2009- Nov 2013

Berlin, Germany

Publications

  1. Hannah S. Sperber, Kyle A. Raymond, Mohamed S. Bouzidi, Tongcui Ma, Silvana Valdebenito, Eliseo Eugenin, Nadia R. Roan, Steven G. Deeks, Sandra Winning, Joachim Fandrey, Roland Schwarzer, Satish K. Pillai. The Hypoxia-regulated Ectonucleotidase CD73 is a Host Determinant of HIV Latency. https://www.cell.com/cell-reports/fulltext/S2211-1247(23)01297-4, Cell Reports ‘Accepted’  LINK
  2. Menke L, Sperber HS, Aji AK, Chiantia S, Schwarzer R, Sieben C. Advances in fluorescence microscopy for orthohantavirus research. Microscopy (Oxf). 2023 Jun 8;72(3):191-203. doi: 10.1093/jmicro/dfac075. Erratum in: Microscopy (Oxf). 2023 Feb 11;: PMID: 36639937. LINK
  3. Sperber HS, Sutter K, Müller K, Müller P, Schwarzer R. The Bovine Seminal Plasma Protein PDC-109 Possesses Pan-Antiviral Activity. Viruses. 2022 Sep 13;14(9):2031. doi: 10.3390/v14092031. PMID: 36146836; PMCID: PMC9504757. LINK
  4. Khanna K, Raymond WW, Jin J, Charbit AR, Gitlin I, Tang M, Werts AD, Barrett EG, Cox JM, Birch SM, Martinelli R, Sperber HS, Franz S, Duff T, Hoffmann M, Healy AM, Oscarson S, Pöhlmann S, Pillai SK, Simmons G, Fahy JV. Exploring antiviral and anti-inflammatory effects of thiol drugs in COVID-19. Am J Physiol Lung Cell Mol Physiol. 2022 Sep 1;323(3):L372-L389. doi: 10.1152/ajplung.00136.2022. Epub 2022 Jun 28. PMID: 35762590; PMCID: PMC9448286. LINK
  5. Welke RW*, Sperber HS*, Bergmann R, Koikkarah A, Menke L, Sieben C, Krüger DH, Chiantia S, Herrmann A, Schwarzer R. Characterization of Hantavirus N Protein Intracellular Dynamics and Localization. Viruses. 2022 Feb 23;14(3):457. doi: 10.3390/v14030457. PMID: 35336863; PMCID: PMC8954124. LINK
  6. Nair RR, Zabezhinsky D, Gelin-Licht R, Haas BJ, Dyhr MC, Sperber HS, Nusbaum C, Gerst JE. Multiplexed mRNA assembly into ribonucleoprotein particles plays an operon-like role in the control of yeast cell physiology. Elife. 2021 May 4;10:e66050. doi: 10.7554/eLife.66050. PMID: 33942720; PMCID: PMC8137142. LINK
  7. Gramatica A, Schwarzer R, Brantley W, Varco-Merth B, Sperber HS, Hull PA, Montano M, Migueles SA, Rosenthal D, Hogan LE, Johnson JR, Packard TA, Grimmett ZW, Herzig E, Besnard E, Nekorchuk M, Hsiao F, Deeks SG, Snape M, Kiernan B, Roan NR, Lifson JD, Estes JD, Picker LJ, Verdin E, Krogan NJ, Henrich TJ, Connors M, Ott M, Pillai SK, Okoye AA, Greene WC. Evaluating a New Class of AKT/mTOR Activators for HIV Latency Reversing Activity <i>Ex Vivo and In Vivo</i>. J Virol. 2021 Mar 25;95(8):e02393-20. doi: 10.1128/JVI.02393-20. Epub 2021 Feb 3. PMID: 33536176; PMCID: PMC8103695. LINK
  8. Sperber HS*, Togarrati PP*, Raymond KA, Bouzidi MS, Gilfanova R, Gutierrez AG, Muench MO, Pillai SK. μ-Lat: A mouse model to evaluate human immunodeficiency virus eradication strategies. FASEB J. 2020 Nov;34(11):14615-14630. doi: 10.1096/fj.202001612RR. Epub 2020 Sep 9. PMID: 32901981; PMCID: PMC8787083. LINK
  9. Chavez LR, Reddy NR, Raymond KA, Bouzidi MS, Desai S, Dossani ZY, Sperber HS, Theiler J, Korber B, Pillai SK. Durable Control of HIV-1 Using a Staphylococcus aureus Cas9-Expressing Lentivirus Co-Targeting Viral Latency and Host Susceptibility. bioRxiv [Preprint]. 2020 Aug;2020.08.10.243329. LINK
  10. Bauherr S, Larsberg F, Petrich A, Sperber HS, Klose-Grzelka V, Luckner M, Azab W, Schade M, Höfer CT, Lehmann MJ, Witkowski PT, Krüger DH, Herrmann A, Schwarzer R. Macropinocytosis and Clathrin-Dependent Endocytosis Play Pivotal Roles for the Infectious Entry of Puumala Virus. J Virol. 2020 Jul 1;94(14):e00184-20. doi: 10.1128/JVI.00184-20. PMID: 32350075; PMCID:PMC7343216. LINK
  11. Sperber HS*, Welke RW*, Petazzi RA, Bergmann R, Schade M, Shai Y, Chiantia S, Herrmann A, Schwarzer R. Self-association and subcellular localization of Puumala hantavirus envelope proteins. Sci Rep. 2019 Jan 24;9(1):707. doi: 10.1038/s41598-018-36879-y. PMID: 30679542; PMCID: PMC6345964. LINK
  12. Zabezhinsky D, Sperber H, Gerst JE. Localizing mRNAs Encoding Mitochondrial Proteins in Yeast by Fluorescence Microscopy and Subcellular Fractionation. Methods Mol Biol. 2017;1567:197-216. LINK
  13. Schwarzer, R., Sperber, H. & Paulick, K. Automatische Bildanalyse für Histologie und Immunhistochemie. Biospektrum 22: 720. LINK