Dr. rer. nat. Hannah Sabeth Schwarzer-Sperber
Professional Experience
Principal InvestigatorInstitute for the Research on HIV and AIDS-associated Diseases |
Jan 2024-presentEssen, Germany |
Postdoctoral FellowInstitute for the Research on HIV and AIDS-associated Diseases |
March 2021-Dec 2023Essen, Germany |
Doctoral Student |
June 2017-March 2021San Francisco, CA |
Research Assistant |
Feb 2017-May 2021San Francisco, CA |
Self-employed Image Analyst |
Aug 2016-Feb 2017Berlin, Germany |
Master's Student |
Sep 2014-May 2016Rehovot, Israel |
Research Student |
Nov 2013-Sep 2014Berlin, Germany |
Bachelor Student |
Feb 2013-Nov 2013Berlin, Germany |
Tutor |
Oct 2010-Dec 2013Berlin, Germany |
Education and Degrees
Dr. rer. nat. |
June 2017-Sep 2021Berlin, Germany |
Master in Molecular Life Sciences |
Oct 2013-Sep 2016Berlin, Germany |
Bachelor in Biology |
Oct 2009- Nov 2013Berlin, Germany |
Publications
- Hannah S. Sperber, Kyle A. Raymond, Mohamed S. Bouzidi, Tongcui Ma, Silvana Valdebenito, Eliseo Eugenin, Nadia R. Roan, Steven G. Deeks, Sandra Winning, Joachim Fandrey, Roland Schwarzer, Satish K. Pillai. The Hypoxia-regulated Ectonucleotidase CD73 is a Host Determinant of HIV Latency. https://www.cell.com/cell-reports/fulltext/S2211-1247(23)01297-4, Cell Reports ‘Accepted’ LINK
- Menke L, Sperber HS, Aji AK, Chiantia S, Schwarzer R, Sieben C. Advances in fluorescence microscopy for orthohantavirus research. Microscopy (Oxf). 2023 Jun 8;72(3):191-203. doi: 10.1093/jmicro/dfac075. Erratum in: Microscopy (Oxf). 2023 Feb 11;: PMID: 36639937. LINK
- Sperber HS, Sutter K, Müller K, Müller P, Schwarzer R. The Bovine Seminal Plasma Protein PDC-109 Possesses Pan-Antiviral Activity. Viruses. 2022 Sep 13;14(9):2031. doi: 10.3390/v14092031. PMID: 36146836; PMCID: PMC9504757. LINK
- Khanna K, Raymond WW, Jin J, Charbit AR, Gitlin I, Tang M, Werts AD, Barrett EG, Cox JM, Birch SM, Martinelli R, Sperber HS, Franz S, Duff T, Hoffmann M, Healy AM, Oscarson S, Pöhlmann S, Pillai SK, Simmons G, Fahy JV. Exploring antiviral and anti-inflammatory effects of thiol drugs in COVID-19. Am J Physiol Lung Cell Mol Physiol. 2022 Sep 1;323(3):L372-L389. doi: 10.1152/ajplung.00136.2022. Epub 2022 Jun 28. PMID: 35762590; PMCID: PMC9448286. LINK
- Welke RW*, Sperber HS*, Bergmann R, Koikkarah A, Menke L, Sieben C, Krüger DH, Chiantia S, Herrmann A, Schwarzer R. Characterization of Hantavirus N Protein Intracellular Dynamics and Localization. Viruses. 2022 Feb 23;14(3):457. doi: 10.3390/v14030457. PMID: 35336863; PMCID: PMC8954124. LINK
- Nair RR, Zabezhinsky D, Gelin-Licht R, Haas BJ, Dyhr MC, Sperber HS, Nusbaum C, Gerst JE. Multiplexed mRNA assembly into ribonucleoprotein particles plays an operon-like role in the control of yeast cell physiology. Elife. 2021 May 4;10:e66050. doi: 10.7554/eLife.66050. PMID: 33942720; PMCID: PMC8137142. LINK
- Gramatica A, Schwarzer R, Brantley W, Varco-Merth B, Sperber HS, Hull PA, Montano M, Migueles SA, Rosenthal D, Hogan LE, Johnson JR, Packard TA, Grimmett ZW, Herzig E, Besnard E, Nekorchuk M, Hsiao F, Deeks SG, Snape M, Kiernan B, Roan NR, Lifson JD, Estes JD, Picker LJ, Verdin E, Krogan NJ, Henrich TJ, Connors M, Ott M, Pillai SK, Okoye AA, Greene WC. Evaluating a New Class of AKT/mTOR Activators for HIV Latency Reversing Activity <i>Ex Vivo and In Vivo</i>. J Virol. 2021 Mar 25;95(8):e02393-20. doi: 10.1128/JVI.02393-20. Epub 2021 Feb 3. PMID: 33536176; PMCID: PMC8103695. LINK
- Sperber HS*, Togarrati PP*, Raymond KA, Bouzidi MS, Gilfanova R, Gutierrez AG, Muench MO, Pillai SK. μ-Lat: A mouse model to evaluate human immunodeficiency virus eradication strategies. FASEB J. 2020 Nov;34(11):14615-14630. doi: 10.1096/fj.202001612RR. Epub 2020 Sep 9. PMID: 32901981; PMCID: PMC8787083. LINK
- Chavez LR, Reddy NR, Raymond KA, Bouzidi MS, Desai S, Dossani ZY, Sperber HS, Theiler J, Korber B, Pillai SK. Durable Control of HIV-1 Using a Staphylococcus aureus Cas9-Expressing Lentivirus Co-Targeting Viral Latency and Host Susceptibility. bioRxiv [Preprint]. 2020 Aug;2020.08.10.243329. LINK
- Bauherr S, Larsberg F, Petrich A, Sperber HS, Klose-Grzelka V, Luckner M, Azab W, Schade M, Höfer CT, Lehmann MJ, Witkowski PT, Krüger DH, Herrmann A, Schwarzer R. Macropinocytosis and Clathrin-Dependent Endocytosis Play Pivotal Roles for the Infectious Entry of Puumala Virus. J Virol. 2020 Jul 1;94(14):e00184-20. doi: 10.1128/JVI.00184-20. PMID: 32350075; PMCID:PMC7343216. LINK
- Sperber HS*, Welke RW*, Petazzi RA, Bergmann R, Schade M, Shai Y, Chiantia S, Herrmann A, Schwarzer R. Self-association and subcellular localization of Puumala hantavirus envelope proteins. Sci Rep. 2019 Jan 24;9(1):707. doi: 10.1038/s41598-018-36879-y. PMID: 30679542; PMCID: PMC6345964. LINK
- Zabezhinsky D, Sperber H, Gerst JE. Localizing mRNAs Encoding Mitochondrial Proteins in Yeast by Fluorescence Microscopy and Subcellular Fractionation. Methods Mol Biol. 2017;1567:197-216. LINK
- Schwarzer, R., Sperber, H. & Paulick, K. Automatische Bildanalyse für Histologie und Immunhistochemie. Biospektrum 22: 720. LINK