Alireza Doustmohammadi
PhD candidate in Computational Biomedicine
Affiliated with:
Farahpour Lab Department of Bioinformatics and Computational Biophysicsalireza.dostmohammadi[at]uni-due.de
Faculty of Biology, University of Duisburg-Essen, Universitätsstr. 2, 45141 Essen
+49 201 183 3092
Research Summary
Reciprocal interactions between the tumor microenvironment and the lesional microbiome Mycosis fungoides (MF), the most prevalent cutaneous T-cell lymphoma, is characterized by malignant T-cell proliferation within a chronic inflammatory environment with variable disease progression from indolent to aggressive forms. Our hypothesis is that the interaction between malignant and reactive T cells in MF lesions is influenced by the microbiome, thereby affecting disease progression. Our research aims to link these interactions with the microbiome to identify prognostic markers and develop novel therapies. Methods: Immune repertoire analysis, Microbial read detection, Microbial functional analysis, Cell-Cell communication. Funded by: DFG