Prof. Dr. Christian Johannes

Molecular Genetics I

Prof. Dr. Christian Johannes

© ZMB, Carola Schubert (2019)
Contact

Prof. Dr. Christian Johannes

Faculty of Biology
Center of Medical Biotechnology
University of Duisburg-Essen

  • +49 201 183 -2834
  • E-mail
  • S05 T04 B05
Publications

    Journal articles

  • Šumbera, R.; Uhrová, M.; Begall, Sabine; Caspar, Kai R.; Jerkovičová, D.; Van Daele, P.; Chitaukali, W.N.; Faulkes, C.G.; Bennett, N.C.; Johannes, Christian; Burda, H.; Mikula, O.
    The biology of an isolated Mashona mole-rat population from southern Malawi, with implications for the diversity and biogeography of the genus Fukomys
    In: Organisms Diversity and Evolution Vol. 23 (2023) Nr. 3, pp. 603 - 620
    Online Full Text: dx.doi.org/ (Open Access)
  • Schmidt, Nina; Irle, Inga; Ripkens, Kamilla; Lux, Vanda; Nelles, Jasmin; Johannes, Christian; Parry, Lee; Greenow, Kirsty; Amir, Sarah; Campioni, Mara; Baldi, Alfonso; Oka, Chio; Kawaichi, Masashi; Clarke, Alan R.; Ehrmann, Michael
    Epigenetic silencing of serine protease HTRA1 drives polyploidy
    In: BMC Cancer Vol. 16 (2016) Nr. 1,
    Online Full Text: dx.doi.org/ (Open Access)
  • Daschkey, Svenja; Bienemann, Kirsten; Schuster, Volker; Kreth, Hans Wolfgang; Linka, René Martin; Hönscheid, Andrea; Fritz, Gerhard; Johannes, Christian; Fleckenstein, Bernhard; Kempkes, Bettina; Gombert, Michael; Ginzel, Sebastian; Borkhardt, Arndt
    Fatal Lymphoproliferative Disease in Two Siblings Lacking Functional FAAP24
    In: Journal of Clinical Immunology Vol. 36 (2016) Nr. 7, pp. 684 - 692
    Online Full Text: dx.doi.org/
  • Ahlberg, Sebastian; Antonopulos, Alexandra; Diendorf, Jörg; Dringen, Ralf; Epple, Matthias; Flöck, Rebekka; Goedecke, Wolfgang; Graf, Christina; Haberl, Nadine; Helmlinger, Jens; Herzog, Fabian; Heuer, Frederike; Hirn, Stephanie; Johannes, Christian; Kittler, Stefanie; Köller, Manfred; Korn, Katrin; Kreyling, Wolfgang G.; Krombach, Fritz; Lademann, Jürgen; Loza, Kateryna; Luther, Eva M.; Malissek, Marcelina; Meinke, Martina C.; Nordmeyer, Daniel; Pailliart, Anne; Raabe, Jörg; Rancan, Fiorenza; Rothen-Rutishauser, Barbara; Rühl, Eckart; Schleh, Carsten; Seibel, Andreas; Sengstock, Christina; Treuel, Lennart; Vogt, Annika; Weber, Katrin; Zellner, Reinhard
    PVP-coated, negatively charged silver nanoparticles : A multi-center study of their physicochemical characteristics, cell culture and in vivo experiments
    In: Beilstein Journal of Nanotechnology Vol. 5 (2014) pp. 1944 - 1965
    Online Full Text: dx.doi.org/ (Open Access)
  • Johnen, Georg; Rozynek, Peter; Gathen, Yvonne von der; Bryk, Oleksandr; Zdrenka, Ricarda; Johannes, Christian; Weber, Daniel; Igwilo-Okuefuna, O'Brien; Raiko, Irina; Hippler, Jörg; Brüning, Thomas; Dopp, Elke
    Cross-contamination of a UROtsa stock with T24 cells : molecular comparison of different cell lines and stocks
    In: PLoS ONE Vol. 8 (2013) Nr. 5, pp. e64139
    Online Full Text: dx.doi.org/ (Open Access)
  • Wülling, Manuela; Pasdziernik, Markus; Moll, Carina; Thiesen, Andrea; Schneider, Sabine; Johannes, Christian; Vortkamp, Andrea
    The multi zinc-finger protein Trps1 acts as a regulator of histone deacetylation during mitosis
    In: Cell Cycle Vol. 12 (2013) Nr. 14, pp. 2219 - 2232
    Online Full Text: dx.doi.org/
  • Obe, Guenter; Johannes, Christian; Ritter, Sylvia
    The number and not the molecular structure of DNA double-strand breaks is more important for the formation of chromosomal aberrations : A hypothesis
    In: Mutation Research / Genetic Toxicology and Environmental Mutagenesis Vol. 701 (2010) Nr. 1, pp. 3 - 11
    Online Full Text: dx.doi.org/
  • Johannes, Christian; Dixius, Anne; Pust, Mareike; Hentschel, Reinhard; Buraczewska, Iwona; Staaf, Elina; Brehwens, Karl; Haghdoost, Siamak; Nievaart, Sander; Czub, Joanna; Braziewicz, Janusz; Wojcik, Andrzej
    The yield of radiation-induced micronuclei in early and late-arising binucleated cells depends on radiation quality
    In: Mutation Research / Genetic Toxicology and Environmental Mutagenesis Vol. 701 (2010) Nr. 1, pp. 80 - 85
    Online Full Text: dx.doi.org/
  • Horstmann, M.; Durante, M.; Johannes, Christian; Obe, G.
    Chromosomal intrachanges induced by swift iron ions
    In: Advances in Space Research Vol. 35 (2005) Nr. 2, pp. 276 - 279
    Online Full Text: dx.doi.org/
  • Müller, Wolfgang-Ulrich; Ciborovius, Jens; Bauch, Thomas; Johannes, Christian; Schunck, Christian; Mallek, Ulrike; Bocker, Wilfried; Obe, Günter; Streffer, Christian
    Analysis of the Action of the Restriction Endonuclease AluI Using Three Different Comet Assay Protocols
    In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Vol. 180 (2004) Nr. 10, pp. 655 - 664
    Online Full Text: dx.doi.org/
  • Johannes, Christian; Horstmann, M.; Durante, M.; Chudoba, I.; Obe, Günter
    Chromosome intrachanges and interchanges detected by multicolor banding in lymphocytes : searching for clastogen signatures in the human genome
    In: Radiation Research Vol. 161 (2004) Nr. 5, pp. 540 - 548
    Online Full Text: dx.doi.org/
  • Johannes, Christian; Horstmann, M.; Durante, Marco; Chudoba, Ilse; Obe, Günter
    Reply to “Comments on ‘Chromosome Intrachanges and Interchanges Detected by Multicolor Banding in Lymphocytes: Searching for Clastogen Signatures in the Human Genome’ by Johanneset al.(Radiat. Res.161, 540– 548, 2004),” by David J. Brenner
    In: Radiation Research Vol. 162 (2004) pp. 601 - 601
    Online Full Text: dx.doi.org/
  • Obe, Günter; Pfeiffer, P.; Savage, J.R.; Johannes, Christian; Goedecke, W.; Jeppesen, P.; Natarajan, A.T.; Martinez-Lopez, W.; Folle, G.A.; Drets, M.E.
    Chromosomal aberrations : Formation, identification and distribution
    In: Mutation Research / Fundamental and Molecular Mechanisms of Mutagenesis Vol. 504 (2002) Nr. 1-2, pp. 17 - 36
    Online Full Text: dx.doi.org/
  • Johannes, Christian; Chudoba, Ilse; Obe, Günter
    Analysis of X-ray induced aberrations in human chromosome 5 using high resolution multi-colour banding FISH (mBAND)
    In: Chromosome Research Vol. 7 (1999) Nr. 8, pp. 625 - 633
    Online Full Text: dx.doi.org/
  • Johannes, Christian; Schunck, Christian; Hüsing, Johannes; Obe, Günter
    Influence of sodium butyrate on the induction of radiation-induced chromosomal aberrations and sister chromatid exchanges in Chinese hamster ovary (CHO) cells
    In: Mutation Research / Fundamental and Molecular Mechanisms of Mutagenesis Vol. 429 (1999) Nr. 1, pp. 141 - 146
    Online Full Text: dx.doi.org/
  • Obe, Günter; Facius, R.; Reitz, G.; Johannes, I.; Johannes, Christian
    Manned missions to Mars and chromosome damage
    In: International Journal of Radiation Biology (RAB) Vol. 75 (1999) Nr. 4, pp. 429 - 433
    Online Full Text: dx.doi.org/
  • Obe, G.; Johannes, I.; Johannes, Christian; Hallmann, K.; Reitz, G.; Facius, R.
    Chromosomal aberrations in blood lymphocytes of astronauts after long-term space flights
    In: International Journal of Radiation Biology (RAB) Vol. 72 (1997) Nr. 6, pp. 727 - 734
    Online Full Text: dx.doi.org/
  • Obe, G.; Johannes, I.; Johannes, Christian; Heckeley, N.; Hallmann, K.; Reitz, G.
    Chromosomenaberrationen bei Astronauten
    In: Flugmagazin Vol. 30 (1997) Nr. 4, pp. 4 - 5
  • Haas, K.; Johannes, Christian; Blass Kampmann, S.; Schmidt, T.; Karsunky, H.; Obe, G.; Möröy, T.
    Cooperation of cyclin E and Ha-ras efficiently generates malignantly transformed and polyploid cells but depends on functional Myc and CDK4
    In: European Journal of Cell Biology (EJCB) Vol. 72 (1997) Nr. 1, pp. 15
  • Johannes, Christian; Heller, W.D.; Eke, P.; Obe, G.
    Frequencies of polycentric chromosomes following combinational treatments of Chinese hamster ovary cells with restriction endonucleases and X-ray, bleomycin or DNase I
    In: Mutation Research / Fundamental and Molecular Mechanisms of Mutagenesis Vol. 373 (1997) Nr. 2, pp. 237 - 244
    Online Full Text: dx.doi.org/
  • Haas, Kirsten; Johannes, Christian; Geisen, Christoph; Schmidt, Thorsten; Karsunky, Holger; Blass-Kampmann, Sabine; Obe, Günter; Möröy, Tarik
    Malignant transformation by cyclin E and Ha-Ras correlates with lower sensitivity towards induction of cell death but requires functional Myc and CDK4
    In: Oncogene Vol. 15 (1997) Nr. 21, pp. 2615 - 2623
    Online Full Text: dx.doi.org/
  • Johannes, Christian; Obe, Günter
    Ultrasound permeabilizes CHO cells for the endonucleases AluI and benzon nuclease
    In: Mutation Research / Fundamental and Molecular Mechanisms of Mutagenesis Vol. 374 (1997) Nr. 2, pp. 245 - 251
    Online Full Text: dx.doi.org/
  • Obe, Günter; Eke, Petra; Johannes, Christian
    Exposure of CHO cells to AluI : comparison of chromosomal aberrations and cell survival
    In: Mutation Research: Fundamental and Molecular Mechanisms of Mutagenesis Vol. 326 (1995) Nr. 2, pp. 171 - 174
    Online Full Text: dx.doi.org/
  • Johannes, Christian; Obe, Günter
    Combination treatments of Chinese hamster ovary cells with various restriction endonucleases results in chromosomal aberaations whose frequencies are additive or less than additive
    In: Mutation Research: Fundamental and Molecular Mechanisms of Mutagenesis Vol. 309 (1994) Nr. 2, pp. 211 - 217
    Online Full Text: dx.doi.org/
  • Johannes, Christian; Obe, Günter
    Induction of chromosomal aberrations with benzon nuclease in Chinese hamster ovary (CHO) cells
    In: Mutation Research Letters Vol. 325 (1994) pp. 113 - 116
    Online Full Text: dx.doi.org/
  • Obe, Günter; Schunck, Christian; Johannes, Christian
    Induction of sister-chromatid exchanges by AluI, DNase I, benzon nuclease and bleomycin in Chinese hamster ovary (CHO) cells
    In: Mutation Research: Fundamental and Molecular Mechanisms of Mutagenesis Vol. 307 (1994) Nr. 1, pp. 315 - 321
    Online Full Text: dx.doi.org/
  • Weissenborn, U.; Johannes, Christian; Raesfeld, C.; Obe, G.
    Potentiation of the cytogenetic effects of bleomycin in mammalian cells by membrane permeabilization
    In: Biologisches Zentralblatt Vol. 113 (1994) pp. 53 - 67
  • Obe, Günter; Johannes, Christian; Werthmann, Iris; Folle, Gustavo A.
    Chromatid-type aberrations induced by AluI in Chinese hamster ovary cells.
    In: Mutation Research: Genetic Toxology Vol. 299 (1993) Nr. 3-4, pp. 305 - 311
    Online Full Text: dx.doi.org/
  • Obe, G.; Johannes, Christian
    Chromosomal aberrations induced with endonucleases. Review Article.
    In: (Rev. Brasis. Genet.) Vol. 16 (1993) Nr. 3, pp. 849 - 855
  • Obe, G.; Johannes, Christian; Schulte-Frohlinde, D.
    DNA-double strand breaks induced by sparsely ionizing radiation and endonucleases as critical lesions for all death, chromosomal aberrations, mutations and oncogenic transformation
    In: Mutagenesis Vol. 7 (1992) Nr. 1, pp. 3 - 12
    Online Full Text: dx.doi.org/
  • Folle, G.A.; Johannes, Christian; Mechoso, B.H.; Medina, I.I.; Obe, G.
    The restriction endonuclease Alu I induces sister chromatid exchange in chinese hamster ovary cells
    In: Mutagenesis Vol. 7 (1992) Nr. 4, pp. 291 - 294
    Online Full Text: dx.doi.org/
  • Johannes, Christian; Boes, R.; Obe, G.
    Uptake of the restriction endonuclease AluI by Chinese hamster ovary cells measured by frequencies of induced chromosomal aberrations : effect of hypertonic concentrations of glycerol and sorbitol
    In: Mutagenesis Vol. 7 (1992) Nr. 3, pp. 225 - 232
    Online Full Text: dx.doi.org/
  • Johannes, Christian; Obe, G.
    Induction of Chromosomal Aberrations with the Restriction Endonuclease AluI in Chinese Hamster Ovary Cells : Comparison of Different Treatment Methods
    In: International Journal of Radiation Biology (RAB) Vol. 59 (1991) Nr. 6, pp. 1379 - 1393
    Online Full Text: dx.doi.org/
  • Folle, G.A.; Johannes, Christian; Obe, G.
    Induction of chromosomal aberrations by DNaseI.
    In: International Journal of Radiation Biology (RAB) Vol. 59 (1991) Nr. 6, pp. 1371 - 1378
    Online Full Text: dx.doi.org/
  • Johannes, Christian; Tuschy, S.; Lamprecht, I.; Obe, Günter
    The intercellular distributions of chromosomal aberrations induced by the restriction endonucleases Alu I and Bam HI in Chinese hamster ovary cells are overdispersed
    In: Biologisches Zentralblatt Vol. 108 (1989) pp. 445 - 451
  • Obe, Günter; Johannes, Christian
    Chromosomal aberrations induced by the restriction endonucleases Alu I and Bam HI : Comparison with X-rays
    In: Biologisches Zentralblatt Vol. 106 (1987) pp. 175 - 190
  • Obe, Günter; Johannes, Christian; Vasudev, Venkateshaiah; Kasper, P.; Lamprecht, Ingolf H. D.
    Induction of chromosomal aberrations in Chinese hamster ovary cells by the restriction endonuclease Dra I : dose-effect relationships and effect of substitution of chromosomal DNA with bromodeoxyuridine
    In: Mutation Research Letters Vol. 192 (1987) Nr. 4, pp. 263 - 269
    Online Full Text: dx.doi.org/
  • Gustavino, Bianca; Johannes, Christian; Obe, Günter
    Restriction endonuclease Bam H I induces chromosomal aberrations in Chinese hamster ovary (CHO) cells
    In: Mutation Research Letters Vol. 175 (1986) Nr. 2, pp. 91 - 95
    Online Full Text: dx.doi.org/