CRC1093 Member Jens Voskuhl
Prof. Jens Voskuhl
Phone: +49 201 183 2404
Email
Institut für Organische Chemie
Faculty of Chemistry
University of Duisburg-Essen
Biosupramolecular Chemistry Research
Aggregation induced emission (AIE) is a fluorescence phenomenon which occurs contrary to „normal“ fluorophores only in the solid or aggregated mode of an emitting molecule. Our approach is to modify a novel class of these emitters in that way that a fluorescence signal is obtained when a specific binding to a protein surface or pocket occurs. With this method it should be possible to find and evaluate novel binders and inhibitors for various proteins of interest.
Curriculum Vitae
Professional career
| 2015-today |
Juniorprofessor (W1) for Biosupramolecular Chemistry, University of Duisburg-Essen |
| 2015 | Postdoc, University of Münster, Bart Jan Ravoo |
| 2013-2015 |
Postdoc, University of Twente, the Netherlands, Pascal Jonkheijm |
| 2011-2013 | Postdoc, University of Leiden, the Netherlands, Alexander Kros |
Scientific education and degrees
| 2008-2011 | PhD, Chemistry, University of Münster, Bart Jan Ravoo |
| 2002-2008 | Study of Chemistry, University of Münster |
Selected Publications
H. Frisch, D. Spitzer, J. Voskuhl*, P. Besenius*, Probing the Self-Assembly and Stability of Oligohistidine based Rod-like Micelles by Aggregation Induced Luminescence, Org. Biomol. Chem, DOI: 10.1039/C6OB00292G (2016).
O. Roling, L. Stricker, J. Voskuhl, B. J. Ravoo, Surface immobilised polymer brushes as supramolecular glue, Chem. Commun. 52, 1964 (2016).
S. Sankaran, J. van Weerd, J. Voskuhl, M. Karperien, P. Jonkheijm, Photoresponsive Cucurbit[8]uril-Mediated Adhesion of Bacteria on Supported Lipid Bilayers, Small, 46, 6186 (2015).
J. Voskuhl, S. Sankaran, P. Jonkheijm, Optical control over bioactive ligands at supramolecular surfaces, Chem. Commun., 50, 15144 (2014).
C. Stoffelen, J. Voskuhl, P. Jonkheijm, J. Huskens, Dual stimuli responsive supramolecular nanoparticles, Angew. Chem. Int Ed., 53, 3400 (2014).
J. Voskuhl, J. Brinkmann, P. Jonkheijm, Advances in contact printing technologies of carbohydrate, protein and peptide arrays, Curr. Op. Chem. Biol., 18, 1 (2014).
F. Versluis, J. Voskuhl, B. van Kolck, H. R. Zope, M. Bremmer, T. Albregtse, A. Kros, In situ modification of plain liposomes with lipidated coiled coil forming peptides induces efficient membrane fusion, J. Am. Chem. Soc., 21, 8057 (2013).
C. Glotzbach, U. Kauscher, J. Voskuhl, N. S. Kehr, M. C. A. Stuart, R. Fröhlich, H. Galla, B. J. Ravoo, K. Nagura, S. Saito, S. Yamaguchi, E-U Würthwein, Fluorescent Modular Boron Systems based on NNN- and ONO-Tridentate Ligands: Self-Assembly and Cell Imaging, J. Org. Chem., 2013, 9, 4410 (2013).
J. Voskuhl, C. Wendeln, F. Versluis, E.-C. Fritz, O. Roling, H. Zope, C. Schulz, S. Rinnen, Heinrich F. Arlinghaus, B. Jan Ravoo, A. Kros, Immobilisation of Liposomes and Vesicles on Patterned Surfaces via a Peptide Coiled Coil Binding Motif, Angew. Chem. Int. Ed., 50, 12616 (2012).
K. M. Nalluri, J. Voskuhl, J. B. Bultema, E. J. Boekema, B. J. Ravoo, Light-Responsive Capture and Release of DNA in a Ternary Supramolecular Complex. Angew. Chem. Int. Ed., 50, 9747 (2011).
