CRC 1093 - People
Principal Investigators
Area A - Chemical Ligands and Methods
A1: Protein-recognition by supramolecular ligands from focused combinatorial libraries
Since August 2019 the project is supervised by
Prof. Dr. Jens Voskuhl and Prof. Dr. Thomas Schrader
Group of Prof. Dr. Carsten Schmuck †
Organic Chemistry
Faculty of Chemistry, University of Duisburg-Essen
A2: Natural products as starting structures for the development of supramolecular ligands
Prof. Dr. Markus Kaiser
Phone: +49 201 183 4980
Email
Centre for Medical Biotechnology (ZMB)
Faculty of Biology, University of Duisburg-Essen
A3: Designed copolymers and molecular tweezers for protein surface recognition
Prof. Dr. Thomas Schrader
Phone: +49 201 183 3081
Email
Faculty of Chemistry, University of Duisburg-Essen
A5: Protein-specific nanoparticles for cellular uptake
Prof. Dr. Matthias Epple
Phone: +49 201 183 2413
Email
Inorganic Chemistry
Faculty of Chemistry, University of Duisburg-Essen
A6: DNA-based nanocontainers for predesigned spatial confinement of proteins
Prof. Dr. Barbara Saccà
Phone: +49 201 183 3097
Email
Centre for Medical Biotechnology (ZMB)
Faculty of Biology, University of Duisburg-Essen
A7: Pareto-optimization of protein-surface targeting supramolecular binders with hetero-avidity
Prof. Dr. Daniel Hoffmann
Phone: +49 201 183 4391
Email
Centre for Medical Biotechnology (ZMB)
Faculty of Biology, University of Duisburg-Essen
A8: Exploring protein-recognition by supramolecular binders with MD an QM/MM methods
Prof. Dr. Elsa Sánchez-Garcia
Phone: +49 201 183 3839
Email
Centre for Medical Biotechnology (ZMB)
Faculty of Biology, University of Duisburg-Essen
A9: Raman spectroscopic monitoring of protein recognition by supramolecular ligands
Prof. Dr. Sebastian Schlücker
Phone: +49 201 183 6843
Email
Faculty of Chemistry, University of Duisburg-Essen
A10: Novel luminophores with aggregation induced emission properties for protein recognition
Prof. Dr. Jens Voskuhl
Phone: +49 201 183 2404
Email
Biosupramolecular Chemistry, University of Duisburg-Essen
A11: Precision macromolecules for the sequence-controlled presentation of supramolecular ligands
Area B - Biological Targets
B1: Supramolecular ligand modulate assembly and function of HtrA proteases
Prof. Dr. Michael Ehrmann
Phone: +49 201 183 2949
Email
Centre for Medical Biotechnology (ZMB)
Faculty of Biology, University of Duisburg-Essen
B2: Probing mechanisms of the Cdo48/p97 segregase with designed supramolecular ligands
Prof. Dr. Hemmo Meyer
Phone: +49 201 183 4217
Email
Centre for Medical Biotechnology (ZMB)
Faculty of Biology, University of Duisburg-Essen
B4: Modulation of 14-3-3 protein-protein interactions by supramolecular chemistry
This project has been finished in 2020.
Prof. Christian Ottmann
Email , Department of Biomedical Engineering, Eindhoven University of Technology
B5: Dissection and modulation of (patho)biological Survivin functions by supramolecular ligands
Prof. Dr. Shirley Knauer
Phone: +49 201 183 4987
Email
Centre for Medical Biotechnology (ZMB)
Faculty of Biology, University of Duisburg-Essen
B6: Targeting centromer recuitment of mitotic regulators by supramolecular ligands
Hon. Prof. Dr. Andrea Musacchio
Phone: +49 231 133-2101
Email
Department of Mechanistic Cell Biology
Max-Planck-Institut für molekulare Physiologie, Dortmund
B7: Manipulation of the kinetochore-microtubule interface by supramoleular ligands
Prof. Dr. Stefan Westermann
Phone: +49 201 183 2404
Email
Molecular Genetics, ZMB, Faculty of Biology, University of Duisburg-Essen
Area Z - Central Service
Z2: X-Ray Crystallography
Dr. Ingrid Vetter
Phone: +49 231 133-2737
Email
Homepage
Max-Planck-Institut für molekulare Physiologie, Dortmund
Z3: NMR Spectroscopy
Prof. Dr. Peter Bayer
Phone: +49 201 183 4677
Email
Structural and Medicinal Biochemistry
Centre for Medical Biotechnology (ZMB)
Faculty of Biology, University of Duisburg-Essen
Associated Members
AM2: Phosphoric acid based supramolecular ligands
Priv.-Doz. Dr. Jochen Niemeyer
Phone: +49 201 183 3148
Email
Supramolecular Organocatalysis and Chemosensing
AM4: A modular ligand design for protein surfaces – addressing the conformational dynamics of proteins via adaptive GCP-ligands
AM5: Supramolecular ligands for modulating protein interactions of the cytosolic enzyme NGLY1
Dr. Ulla Gerling-Driessen
Phone: +49 211 81-14788
Email
Subgroup Gerling-Driessen - Macromolecular Chemistry, HHU Düsseldorf
Principal Investigators Project Area A
(in alphabetical order)
Principal Investigators Project Area B
(in alphabetical order)
Principal Investigators Project Area Z
(in alphabetical order)