Fakultät für Biologie
Personenverzeichnis
Die Links zu den Personen führen zum zentralen Personenverzeichnis der UDE, das die Daten aus dem LSF ausliest. Persönliche Informationen können im LSF (nach Login mit der Uni-Kennung) selbst bearbeitet werden.
Anschrift
Universitätsstr. 1-5
45141 Essen
45141 Essen
Raum
S03 S01 A35
Telefon
Telefax
E-Mail
Webseite
Sprechzeiten
Termine im Sekretariat erhältlich
Funktionen
-
Vorsitzender, Prüfungsausschuss B.Sc./M.Sc.-Studiengänge Biologie mit Lehramtsoption
-
Universitätsprofessor/in, Strukturelle und Medizinische Biochemie
Aktuelle Veranstaltungen
-
2024 WS
- Biophysikalische Chemie
- Analytikmethoden zur Struktur von Molekülen
- Struktur und Funktion der Zelle (LA Ba)
- MedBio Lab Rotation
- Allgemeine Methoden (Bachelor Bio)
- Physik für Biologen (Bio B.Sc. und Aquatische Bio B.Sc., Molekularbiologie)
- Grundlagen der Biotechnologie (LA Ba); Platzvergabe: 3 Präferenzen angeben
- Physik für Biologen
- ZIA71044 Klausur Struktur/Funktion der Zelle
- Tutorium zur Veranstaltung Biophysik
- Vertiefungsarbeit LA alte LPO und Ba LA
- Allgemeine Methoden Praktikum (Bachelor Bio); Priorität für G1 oder G2
- VO Struktur und Funktion von Biopolymeren
Vergangene Veranstaltungen (max. 10)
-
2024 SS
- Bausteine des Lebens: Einführung in die Biochemie für Hauptstudium LA Chemie, Biotechnik und BSc Chemie Vorlesung/Klausur
- Physiologie für aquatische Biologen
- Struktur und Funktion
- Vertiefungsarbeit LA alte LPO und Ba LA
- ZJA40120 Physik für Biologen
- ZIA71044 Klausur Struktur/Funktion der Zelle
- Biophysik-Praktikum
- Struktur und Funktion (LA Ba) - Anmeldung mit mehreren Prioritäten
-
2023 WS
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
-
Functional Linkers Support Targeting of Multivalent Tweezers to Taspase1In: Chemistry - A European Journal Jg. 30 (2024) Nr. 56, e202401542Online Volltext: dx.doi.org/ (Open Access)
-
Increased Cytotoxicity of Bimetallic Ultrasmall Silver–Platinum Nanoparticles (2 nm) on Cells and Bacteria in Comparison to Silver Nanoparticles of the Same SizeIn: Materials Jg. 17 (2024) Nr. 15, 3702Online Volltext: dx.doi.org/ (Open Access)
-
The Molecular Footprint of Peptides on the Surface of Ultrasmall Gold Nanoparticles (2 nm) Is Governed by Steric DemandIn: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry Jg. 128 (2024) Nr. 17, S. 4266 - 4281Online Volltext: dx.doi.org/
-
Multivalent Molecular Tweezers Disrupt the Essential NDC80 Interaction with MicrotubulesIn: Journal of the American Chemical Society: JACS Jg. 145 (2023) Nr. 28, S. 15251 - 15264Online Volltext: dx.doi.org/
-
Potentiating Tweezer Affinity to a Protein Interface with Sequence-Defined Macromolecules on NanoparticlesIn: Biomacromolecules Jg. 24 (2023) Nr. 8, S. 3666 - 3679Online Volltext: dx.doi.org/
-
The UBX domain in UBXD1 organizes ubiquitin binding at the C-terminus of the VCP/p97 AAA-ATPaseIn: Nature Communications Jg. 14 (2023) Nr. 1, 3258Online Volltext: dx.doi.org/ Online Volltext (Open Access)
-
Ultrastructure and Surface Composition of Glutathione-Terminated Ultrasmall Silver, Gold, Platinum, and Alloyed Silver-Platinum Nanoparticles (2 nm)In: Inorganic Chemistry Jg. 62 (2023) Nr. 42, S. 17470 - 17485Online Volltext: dx.doi.org/
-
Binding Methylarginines and Methyllysines as Free Amino Acids : A Comparative Study of Multiple Host ClassesIn: ChemBioChem Jg. 23 (2022) Nr. 2, e202100502Online Volltext: dx.doi.org/ (Open Access)
-
Dual activity inhibition of threonine aspartase 1 by a single bisphosphate ligandIn: RSC Advances Jg. 12 (2022) Nr. 53, S. 34176 - 34184Online Volltext: dx.doi.org/ (Open Access)
-
Recognition of a Flexible Protein Loop in Taspase 1 by Multivalent Supramolecular TweezersIn: Biomacromolecules Jg. 23 (2022) Nr. 11, S. 4504 - 4518Online Volltext: dx.doi.org/
-
Water-Based Synthesis of Ultrasmall Nanoparticles of Platinum Group Metal Oxides (1.8 nm)In: Inorganic Chemistry Jg. 61 (2022) Nr. 12, S. 5133 - 5147Online Volltext: dx.doi.org/
-
Metal-Ligand Interface and Internal Structure of Ultrasmall Silver Nanoparticles (2 nm)In: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry Jg. 125 (2021) Nr. 21, S. 5645 - 5659Online Volltext: dx.doi.org/
-
New tools to probe the protein surface : Ultrasmall gold nanoparticles carry amino acid bindersIn: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry Jg. 125 (2021) Nr. 1, S. 115 - 127Online Volltext: dx.doi.org/ (Open Access)
-
Peptide-Conjugated Ultrasmall Gold Nanoparticles (2 nm) for Selective Protein TargetingIn: ACS Applied Bio Materials Jg. 4 (2021) Nr. 1, S. 945 - 965Online Volltext: dx.doi.org/ (Open Access)
-
Specific inhibition of the Survivin–CRM1 interaction by peptide-modified molecular tweezersIn: Nature Communications Jg. 12 (2021) Nr. 1, S. 1505Online Volltext: dx.doi.org/ Online Volltext (Open Access)
-
Targeting the Surface of the Protein 14-3-3 by Ultrasmall (1.5 nm) Gold Nanoparticles Carrying the Specific Peptide CRafIn: ChemBioChem Jg. 22 (2021) Nr. 8, S. 1456 - 1463Online Volltext: dx.doi.org/ (Open Access)
-
Auto-inhibition of Mif2/CENP-C ensures centromere-dependent kinetochore assembly in budding yeastIn: The EMBO Journal Jg. 39 (2020) Nr. 14, S. e102938Online Volltext: dx.doi.org/ Online Volltext (Open Access)
-
Functional Disruption of the Cancer-Relevant Interaction between Survivin and Histone H3 with a Guanidiniocarbonyl Pyrrole LigandIn: Angewandte Chemie International Edition Jg. 59 (2020) Nr. 14, S. 5567 - 5571Online Volltext: dx.doi.org/ (Open Access)
-
NMR Spectroscopy of supramolecular chemistry on protein surfacesIn: Beilstein Journal of Organic Chemistry Jg. 16 (2020) S. 2505 - 2522Online Volltext: dx.doi.org/ (Open Access)
-
Targeting of parvulin interactors by diazirine mediated cross-linking discloses a cellular role of human Par14/17 in actin polymerizationIn: Biological Chemistry Jg. 401 (2020) Nr. 8, S. 955 - 968Online Volltext: dx.doi.org/ (Open Access)
-
The other side of the corona : Nanoparticles inhibit the protease taspase1 in a size-dependent mannerIn: Nanoscale Jg. 12 (2020) Nr. 37, S. 19093 - 19103Online Volltext: dx.doi.org/
-
Backbone and side-chain chemical shift assignments of full-length, apo, human Pin1, a phosphoprotein regulator with interdomain allosteryIn: Biomolecular NMR Assignments Jg. 13 (2019) Nr. 1, S. 85 - 89Online Volltext: dx.doi.org/ Online Volltext (Open Access)
-
Click chemistry on the surface of ultrasmall gold nanoparticles (2 nm) for covalent ligand attachment followed by nmr spectroscopyIn: Langmuir Jg. 35 (2019) Nr. 22, S. 7191 - 7204Online Volltext: dx.doi.org/
-
Multivalent Ligands with Tailor-Made Anion Binding Motif as Stabilizers of Protein–Protein InteractionsIn: ChemBioChem Jg. 20 (2019) Nr. 23, S. 2921 - 2926Online Volltext: dx.doi.org/
-
Solution NMR Spectroscopy with Isotope-Labeled Cysteine (¹³C and ¹⁵N) Reveals the Surface Structure of l -Cysteine-Coated Ultrasmall Gold Nanoparticles (1.8 nm)In: Langmuir Jg. 35 (2019) Nr. 3, S. 767 - 778Online Volltext: dx.doi.org/
-
Structural Analysis of the 42 kDa Parvulin of Trypanosoma bruceiIn: Biomolecules Jg. 9 (2019) Nr. 3, 93Online Volltext: dx.doi.org/ Online Volltext (Open Access)
-
Structure of the PUB Domain from Ubiquitin Regulatory X Domain Protein 1 (UBXD1) and Its Interaction with the p97 AAA+ ATPaseIn: Biomolecules Jg. 9 (2019) Nr. 12, 876Online Volltext: dx.doi.org/ Online Volltext (Open Access)
-
Cell entry of a host-targeting protein of oomycetes requires gp96In: Nature Communications Jg. 9 (2018) Nr. 1, S. 2347Online Volltext: dx.doi.org/ (Open Access)
-
Structure and function of the human parvulins Pin1 and Par14/17In: Biological Chemistry Jg. 399 (2018) Nr. 2, S. 101 - 125Online Volltext: dx.doi.org/ (Open Access)
-
The RxLR motif of the host targeting effector AVR3a of phytophthora infestans is cleaved before secretionIn: The Plant Cell Jg. 29 (2017) Nr. 6, S. 1184 - 1195Online Volltext: dx.doi.org/ Online Volltext (Open Access)
-
Determinants of tyrosylprotein sulfation coding and substrate specificity of tyrosylprotein sulfotransferases in metazoansIn: Chemico-Biological Interactions Jg. 259 (2016) Nr. Part A, S. 17 - 22Online Volltext: dx.doi.org/
-
Molecular tweezers target a protein-protein interface and thereby modulate complex formationIn: Chemical Communications: ChemComm Jg. 52 (2016) Nr. 98, S. 14141 - 14144Online Volltext: dx.doi.org/ (Open Access)
-
NmPin from the marine thaumarchaeote Nitrosopumilus maritimus is an active membrane associated prolyl isomeraseIn: BMC Biology (incorporating Journal of Biology) Jg. 14 (2016) Nr. 1, S. 53Online Volltext: dx.doi.org/ Online Volltext (Open Access)
-
Structural Characterization of the Loop at the Alpha-Subunit C-Terminus of the Mixed Lineage Leukemia Protein Activating Protease Taspase1In: PLoS ONE Jg. 11 (2016) Nr. 3, S. e0151431Online Volltext: dx.doi.org/ Online Volltext (Open Access)
-
Heterodimers of Tyrosylprotein Sulfotransferases Suggest Existence of a Higher Organization Level of Transferases in the Membrane of the trans-Golgi ApparatusIn: Journal of Molecular Biology (JMB) Jg. 427 (2015) Nr. Issue 6, Part B, S. 1404 - 1412Online Volltext: dx.doi.org/
-
Human DNA-binding peptidyl-prolyl cis/trans isomerase Par14 is cell cycle dependently expressed and associates with chromatin in vivoIn: BMC Biochemistry Jg. 16 (2015) Nr. 1,Online Volltext: dx.doi.org/ Online Volltext (Open Access)
-
Structural model of the bilitranslocase transmembrane domain supported by NMR and FRET dataIn: PLoS ONE Jg. 10 (2015) Nr. 8, S. e0135455Online Volltext: dx.doi.org/ (Open Access)
-
The N-terminal region of the ubiquitin regulatory X (UBX) domain-containing protein 1 (UBXD1) modulates interdomain communication within the valosin-containing protein p97In: The Journal of Biological Chemistry (JBC) Jg. 290 (2015) Nr. 49, S. 29414 - 29427Online Volltext: dx.doi.org/ (Open Access)
-
Peptidyl succinimidyl peptides as taspase 1 inhibitorsIn: ChemBioChem Jg. 15 (2014) Nr. 15, S. 2233 - 2237Online Volltext: dx.doi.org/
-
Design of a Modular Protein-Based MRI Contrast Agent for Targeted ApplicationIn: PLoS ONE Jg. 8 (2013) Nr. 6, S. e65346Online Volltext: dx.doi.org/ Online Volltext (Open Access)
-
Identification and characterization of peptides that bind the PPIase domain of Parvulin17In: Journal of Peptide Science Jg. 19 (2013) Nr. 6, S. 362 - 369Online Volltext: dx.doi.org/
-
Transient domain interactions enhance the affinity of the mitotic regulator pin1 toward phosphorylated peptide ligandsIn: Structure Jg. 21 (2013) Nr. 10, S. 1769 - 1777Online Volltext: dx.doi.org/ (Open Access)
-
Document Human PAPS synthase isoforms are dynamically regulated enzymes with access to nucleus and cytoplasmIn: PLoS ONE Jg. 7 (2012) Nr. 1, S. e29559Online Volltext: dx.doi.org/ Online Volltext (Open Access)
-
Host-targeting protein 1 (SpHtp1) from the oomycete Saprolegnia parasitica translocates specifically into fish cells in a tyrosine-O-sulphate-dependent mannerIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 109 (2012) Nr. 6, S. 2096 - 2101Online Volltext: dx.doi.org/
-
Structure of the corrinoid : coenzyme M methyltransferase MtaA from Methanosarcina mazeiIn: Acta Crystallographica Section D: Biological Crystallography Jg. 68 (2012) Nr. 11, S. 1549 - 1557Online Volltext: dx.doi.org/
-
A potential transcriptional regulator is out-of-frame translated from the metallothionein 2A messenger RNAIn: Analytical Biochemistry Jg. 409 (2011) Nr. 1, S. 159 - 161Online Volltext: dx.doi.org/
-
Crystallographic Proof for an Extended Hydrogen Bonding Network in Small Prolyl IsomerasesIn: Journal of the American Chemical Society: JACS Jg. 133 (2011) Nr. 50, S. 20096 - 20099Online Volltext: dx.doi.org/ Online Volltext
-
Single-Domain Parvulins Constitute a Specific Marker for Recently Proposed Deep-Branching Archaeal SubgroupsIn: Evolutionary Bioinformatics Jg. 7 (2011) S. 135 - 148Online Volltext: dx.doi.org/ Online Volltext (Open Access)
-
Structure and Dynamics of the First Archaeal Parvulin Reveal a New Functionally Important Loop in Parvulin-type Prolyl IsomerasesIn: The Journal of Biological Chemistry (JBC) Jg. 286 (2011) S. 6554 - 6565Online Volltext: dx.doi.org/ (Open Access)
-
The solution structure of pGolemi, a high affinity Mena EVH1 binding miniature protein, suggests explanations for paralog-specific binding to Ena/VASP homology (EVH) 1 domainsIn: Biological Chemistry Jg. 390 (2009) Nr. 5-6, S. 417 - 426Online Volltext: dx.doi.org/
-
Wie Proteine sich erkennen ... : ... und man ihnen dabei zusehen kann!In: Unikate: Berichte aus Forschung und Lehre (2009) Nr. 36: Naturwissenschaften/Medizin : Kernmagnetische Resonanz, S. 28 - 35Online Volltext: dx.doi.org/ Online Volltext (Open Access)
-
Small family with key contacts : par14 and par17 parvulin proteins, relatives of pin1, now emerge in biomedical researchIn: Perspectives in Medicinal Chemistry Jg. 2 (2008) S. 11 - 20Online Volltext: dx.doi.org/ (Open Access)
-
15N magnetic relaxation study of backbone dynamics of the ribosomeassociated cold shock response protein Yfia of Escherichia coliIn: Acta Biochimica Polonica Jg. 54 (2007) Nr. 4, S. 769 - 775(Open Access)
-
The DNA binding parvulin Par17 is targeted to the mitochondrial matrix by a recently evolved prepeptide uniquely present in Hominidae.In: BMC Biology (incorporating Journal of Biology) Jg. 5 (2007) S. 37Online Volltext: dx.doi.org/
-
Characterization of novel elongated Parvulin isoforms that are ubiquitously expressed in human tissues and originate from alternative transcription initiation.In: BMC Molecular Biology Jg. 7 (2006) S. 9
-
GTP-Ras disrupts the intramolecular complex of C1 and RA domains of Nore1.In: Structure Jg. 14 (2006) S. 881 - 888Online Volltext: dx.doi.org/ (Open Access)
-
Human TPST1 Transmembrane Domain Triggers Enzyme Dimerisation and Localisation to the Golgi CompartmentIn: Journal of Molecular Biology (JMB) Jg. 361 (2006) Nr. 3, S. 436 - 449Online Volltext: dx.doi.org/
-
Isotopic labelling of recombinant proteins expressed in the protozoan host Leishmania tarentolae.In: Protein Expression & Purification Jg. 48 (2006) S. 167 - 172
-
Specification of SUMO1- and SUMO2-interacting motifsIn: The Journal of Biological Chemistry (JBC) Jg. 281 (2006) Nr. 23, S. 16117 - 16127Online Volltext: dx.doi.org/ (Open Access)
-
Identification of hPin1 inhibitors that induce apoptosis in a mammalian Ras transformed cell lineIn: Chemical Communications: ChemComm Jg. 4 (2005) S. 516 - 518Online Volltext: dx.doi.org/
-
The crystal structure of human PAPS synthetase 1 reveals asymmetry in substrate bindingIn: Journal of Molecular Biology (JMB) Jg. 347 (2005) Nr. 3, S. 623 - 635Online Volltext: dx.doi.org/
-
Expression, purification and crystallization of human 3′- phosphoadenosine-5′-phosphosulfate synthetase 1In: Acta Crystallographica Section D: Structural Biology Jg. 60 (2004) Nr. 2, S. 350 - 352Online Volltext: dx.doi.org/
-
Structure and function of the phenazine biosynthetic protein PhzF from Pseudomonas fluorescensIn: Proceedings of the National Academy of Sciences of the United States of America Jg. 101 (2004) Nr. 47, S. 16431 - 16436Online Volltext: dx.doi.org/ (Open Access)
-
Die Vorliebe für Physik und die StrukturbiologieIn: Nachrichten aus der Chemie Jg. 51 (2003) Nr. 9, S. 917 - 917Online Volltext: dx.doi.org/
-
Phosphorylation of the N-terminal domain regulates subcellular localization and DNA binding properties of the peptidyl-prolyl cis/trans isomerase hPar14In: Journal of Molecular Biology (JMB) Jg. 330 (2003) Nr. 5, S. 955 - 966Online Volltext: dx.doi.org/
-
Structural analysis of the mitotic regulator hPin1 in solution : insights into domain architecture and substrate bindingIn: The Journal of Biological Chemistry (JBC) Jg. 278 (2003) Nr. 28, S. 26183 - 26193Online Volltext: dx.doi.org/ (Open Access)
-
Induction of tyrosylprotein sulfotransferase isoform shift in human endothelial cellsIn: Circulation Jg. 106 (2002) Nr. Suppl. 2, S. 287
-
Letter to the Editor: ¹H, ¹³C and ¹⁵N resonance assignments of the ribosome-associated cold shock response protein Yfia of Escherichia coliIn: Journal of Biomolecular NMR Jg. 23 (2002) Nr. 4, S. 335 - 336Online Volltext: dx.doi.org/
-
Shear stress mediates tyrosylprotein sulfotransferase isoform shift in human endothelial cellsIn: Biochemical and Biophysical Research Communications (BBRC) Jg. 294 (2002) Nr. 3, S. 541 - 546Online Volltext: dx.doi.org/
-
Solution structure of the ribosome-associated cold shock response protein Yfia of Escherichia coliIn: Biochemical and Biophysical Research Communications (BBRC) Jg. 299 (2002) Nr. 5, S. 710 - 714Online Volltext: dx.doi.org/
-
Structural attributes in the conjugation of Ubiquitin, RUB and SUMO to protein substrates.In: Frontiers in Bioscience Jg. 7 (2002) S. 148 - 162
-
The N-terminal basic domain of human parvulin h Par14 is responsible for the entry to the nucleus and high-affinity DNA-bindingIn: Journal of Molecular Biology (JMB) Jg. 321 (2002) Nr. 2, S. 235 - 247Online Volltext: dx.doi.org/
-
Increased backbone flexibility in threonineIn: Biochemistry Jg. 40 (2001) Nr. 27, S. 7957 - 7963Online Volltext: dx.doi.org/
-
Structure prediction of protein complexes by an NMR-based protein docking algorithmIn: Journal of Biomolecular NMR Jg. 20 (2001) Nr. 1, S. 15 - 21Online Volltext: dx.doi.org/
-
NMR solution structure of hPar14 reveals similarity to the peptidyl prolyl cis/trans isomerase domain of the mitotic regulator hPin1 but indicates a different functionality of the proteinIn: Journal of Molecular Biology (JMB) Jg. 301 (2000) Nr. 4, S. 1003 - 1017Online Volltext: dx.doi.org/
-
Nuclear magnetic resonance methods to study RNA-protein complexesIn: Methods in Enzymology Jg. 317: RNA - Ligand Interactions, Part A (2000) S. 198 - 220Online Volltext: dx.doi.org/
-
Solution structures of human parathyroid hormone fragments hPTH(1-34) and hPTH(1-39) and bovine parathyroid hormone fragment bPTH(1-37)In: Biochemical and Biophysical Research Communications (BBRC) Jg. 267 (2000) Nr. 1, S. 213 - 220Online Volltext: dx.doi.org/
-
Book Review: Protein Structure: Determination, Analysis, and Applications for Drug Discovery. Edited by Daniel I. ChasmanIn: ChemBioChem Jg. 5 (2004) Nr. 4, S. 547 - 548Online Volltext: dx.doi.org/
-
A molecular handshakeIn: Trends in Biochemical Sciences Jg. 27 (2002) Nr. 10, S. 502 - 503Online Volltext: dx.doi.org/
-
ATP, a trigger for pain-signalingIn: Trends in Biochemical Sciences Jg. 26 (2001) Nr. 1, S. 12Online Volltext: dx.doi.org/
-
Delta: a mitogenic regulator of human hematopoesisIn: Trends in Biochemical Sciences Jg. 26 (2001) Nr. 5, S. 281Online Volltext: dx.doi.org/
-
Living in the cytosolIn: Trends in Biochemical Sciences Jg. 26 (2001) Nr. 12, S. 702Online Volltext: dx.doi.org/
-
TonB – a mediator of iron uptake in bacteriaIn: Trends in Biochemical Sciences Jg. 26 (2001) Nr. 8, S. 472Online Volltext: dx.doi.org/
-
A NMR-spectra based scoring function for protein dockingIn: Proceedings of the Fifth Annual International Conference on Computational Biology / RECOMB01: The Fifth Annual International Conference on Computational Molecular Biology, Montreal, Quebec, Canada, April 22 - 25, 2001 / Lengauer, Thomas (Hrsg.) 2001, S. 184 - 192Online Volltext: dx.doi.org/
-
HumanbiologieIn: UTB Stuttgart Jg. 4130 (2014) 446 Seiten
-
Rationally designed DNA-origami hosts for protein guest
Nantech2019, Nucleic Acid Nanotechnology: from algorithmic design to biochemical applications, Aalto University, Espoo, Finland May 27-29, 2019,(2019)