Molecular mechanisms linking repair of DNA double strand breaks by alternative end joining to growth factor signaling

Mechanisms of the p97- and ubiquitin-governed radiation response

Sensitization to radiotherapy and chemotherapy by inhibition of epigenetic modifiers in lung cancer cell lines with loss of function mutations in SWI/SNF chromatin remodeling genes, or overexpression of EZH2

Prof. Dr. med. Martin Stuschke
Dr. rer. nat. Ali Sak

Functions and regulations of the replication initiation regulator TopBP1 upon exposure to IR

An old passenger as a new driver: Defining Survivin’s role as a link between replication fork dynamics and radiation response

Role of the tyrosine kinase TrkA and TrkB in checkpoint activation and DSB repair

Identification of novel targets for rational chemoradiotherapy strategies in non-small-cell lung cancer

Elimination of the hypoxia-inducible factor-1α (HIF-1α) in murine tumor stroma: effects on tumor growth and sensitivity to ionizing radiation

Prof. Dr. rer. nat. Jens W. Fischer

Prof. Dr. med. Erich Gulbins
Dr. Alexander Carpinteiro

Importance of Caveolin-1 for modulating the radiation response in the context of tumor-stroma interactions