Publications

Publication Metrics
Patents

    Journal articles

  • Huang, Jing; Jaekel, Andreas; van den Boom, Johannes; Podlesainski, David; Elnaggar, M.; Heuer-Jungemann, A.; Kaiser, Markus; Meyer, Hemmo; Saccà, Barbara
    A modular DNA origami nanocompartment for engineering a cell-free, protein unfolding and degradation pathway
    In: Nature Nanotechnology Vol. 19 (2024) Nr. 10, pp. 1521 - 1531
    Online Full Text: dx.doi.org/ (Open Access)
  • Sueldo, Daniela J.; Godson, Alice; Kaschani, Farnusch; Krahn, Daniel; Kessenbrock, Till; Buscaill, Pierre; Schofield, Christopher J.; Kaiser, Markus; van der Hoorn, Renier A. L.
    Activity-based proteomics uncovers suppressed hydrolases and a neo-functionalised antibacterial enzyme at the plant–pathogen interface
    In: New Phytologist Vol. 241 (2024) Nr. 1, pp. 394 - 408
    Online Full Text: dx.doi.org/ (Open Access)
  • Präve, Leonard; Kuttenlochner, Wolfgang; Tabak, Werner W.A.; Langer, Chiara; Kaiser, Markus; Groll, Michael; Bode, Helge B.
    Bioengineering of syrbactin megasynthetases for immunoproteasome inhibitor production
    In: Chem (2024) in press
    Online Full Text: dx.doi.org/ (Open Access)
  • Kaplieva-Dudek, I.; Samak, Nadia A.; Bormann, Jenny; Kaschani, Farnusch; Kaiser, Markus; Meckenstock, Rainer U.
    Characterization of 2-phenanthroate : CoA ligase from the sulfate-reducing, phenanthrene-degrading enrichment culture TRIP
    In: Applied and Environmental Microbiology (2024) in press
    Online Full Text: dx.doi.org/ (Open Access)
  • Kaplieva-Dudek, I.; Samak, Nadia; Bormann, Jenny; Kaschani, Farnusch; Kaiser, Markus; Meckenstock, Rainer
    Characterization of 2-phenanthroate:CoA ligase from the sulfate-reducing, phenanthrene-degrading enrichment culture TRIP
    In: Applied and Environmental Microbiology Vol. 90 (2024) Nr. 10, pp. e0129624
    Online Full Text: dx.doi.org/ (Open Access)
  • Sowislok, Andrea; Busch, André; Kaschani, Farnusch; Kaiser, Markus; Jäger, Marcus
    Differences in the Synovial Fluid Proteome of Septic and Aseptic Implant Failure
    In: Antibiotics Vol. 13 (2024) Nr. 4, 346
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Font-Farre, Maria; Brown, Daniel; Toth, Reka; Mahadevan, Chidambareswaren; Brazier-Hicks, Melissa; Morimoto, Kyoko; Kaschani, Farnusch; Sinclair, John; Dale, Richard; Hall, Samantha; Morris, Melloney; Kaiser, Markus; Wright, Aaron T.; Burton, Jonathan; van der Hoorn, Renier A. L.
    Discovery of active mouse, plant and fungal cytochrome P450s in endogenous proteomes and upon expression in planta
    In: Scientific Reports Vol. 14 (2024) Nr. 1, 10091
    Online Full Text: dx.doi.org/ (Open Access)
  • Ninck, Sabrina; Klaus, Thomas; Kochetkova, Tatiana V.; Esser, Sarah P.; Sewald, Leonard; Kaschani, Farnusch; Bräsen, Christopher; Probst, Alexander J.; Kublanov, Ilya V.; Siebers, Bettina; Kaiser, Markus
    Environmental activity-based protein profiling for function-driven enzyme discovery from natural communities
    In: Environmental Microbiomes Vol. 19 (2024) Nr. 1, 36
    Online Full Text: dx.doi.org/ (Open Access)
  • Chen, Changlong; Buscaill, Pierre; Sanguankiattichai, Nattapong; Huang, Jie; Kaschani, Farnusch; Kaiser, Markus; van der Hoorn, Renier A. L.
    Extracellular plant subtilases dampen cold-shock peptide elicitor levels
    In: Nature Plants (2024) in press
    Online Full Text: dx.doi.org/ (Open Access)
  • Parsons, Jack D.; Cocker, Clare R.; East, Alison K.; Wheatley, Rachel M.; Ramachandran, Vinoy K.; Kaschani, Farnusch; Kaiser, Markus; Poole, Philip S.
    Factors governing attachment of Rhizobium leguminosarum to legume roots at acid, neutral, and alkaline pHs
    In: mSystems Vol. 9 (2024) Nr. 9, e0042224
    Online Full Text: dx.doi.org/ (Open Access)
  • Font Farre, Maria; Brown, Daniel; König, Maurice; Killinger, Brian J.; Kaschani, Farnusch; Kaiser, Markus; Wright, Aaron T.; Burton, Jonathan; van der Hoorn, Renier A.L.
    Glutathione Transferase Photoaffinity Labeling Displays GST Induction by Safeners and Pathogen Infection
    In: Plant and Cell Physiology Vol. 65 (2024) Nr. 1, pp. 128 - 141
    Online Full Text: dx.doi.org/ (Open Access)
  • Schillinger, Jasmin; Koci, Michelle; Bravo-Rodriguez, Kenny; Heilmann, Geronimo; Kaschani, Farnusch; Kaiser, Markus; Beuck, Christine; Luecke, Hartmut; Huber, Robert; Hellerschmied-Jelinek, Doris; Burston, Steven G.; Ehrmann, Michael
    High resolution analysis of proteolytic substrate processing
    In: The Journal of Biological Chemistry (JBC) Vol. 300 (2024) Nr. 11, 107812
    Online Full Text: dx.doi.org/ (Open Access)
  • Pol, Savina Abraham; Liljenberg, Sara; Barr, Jack; Simon, Gina; Wong-Dilworth, Luis; Paterson, Danielle L.; Berishvili, Vladimir P.; Bottanelli, Francesca; Kaschani, Farnusch; Kaiser, Markus; Pettersson, Mariell; Hellerschmied, Doris
    Induced degradation of SNAP-fusion proteins
    In: RSC Chemical Biology (2024) in press
    Online Full Text: dx.doi.org/; Online Full Text: dx.doi.org/ (Open Access)
  • Pleuger, Richard; Cozma, Christian; Hohoff, Simone; Denkhaus, Christian; Dudziak, Alexander; Kaschani, Farnusch; Kaiser, Markus; Musacchio, Andrea; Vetter, Ingrid R.; Westermann, Stefan
    Microtubule end-on attachment maturation regulates Mps1 association with its kinetochore receptor
    In: Current Biology Vol. 34 (2024) Nr. 11, pp. 2279 - 2293.e6
    Online Full Text: dx.doi.org/ (Open Access)
  • Beaufort, Nathalie; Ingendahl, Linda; Merdanovic, Melisa; Schmidt, Andree; Podlesainski, David; Richter, Tim; Neumann, Thorben; Kuszner, Michael; Vetter, Ingrid R.; Stege, Patricia; Burston, Steven G.; Filipovic, Anto; Ruiz-Blanco, Yasser B.; Bravo Rodriguez, Kenny; Mieres-Perez, Joel; Beuck, Christine; Uebel, Stephan; Zobawa, Monika; Schillinger, Jasmin; Malik, Rainer; Todorov-Völgyi, Katalin; Rey, Juliana; Roberti, Annabell; Hagemeier, Birte; Wefers, Benedikt; Müller, Stephan A.; Wurst, Wolfgang; Sanchez-Garcia, Elsa; Zimmermann, Alexander; Hu, Xiao-Yu; Clausen, Tim; Huber, Robert; Lichtenthaler, Stefan F.; Schmuck, Carsten; Giese, Michael; Kaiser, Markus; Ehrmann, Michael; Dichgans, Martin
    Rational correction of pathogenic conformational defects in HTRA1
    In: Nature Communications Vol. 15 (2024) Nr. 1, 5944
    Online Full Text: dx.doi.org/ (Open Access)
  • Podlesainski, David; Adeniyi, Emmanuel T.; Gröner, Yvonne; Schulz, Florian; Krisilia, Violetta; Rehberg, Nidja; Richter, Tim; Sehr, Daria; Xie, Huzhuyue; Simons, Viktor E.; Kiffe-Delf, Anna-Lene; Kaschani, Farnusch; Ioerger, Thomas R.; Kaiser, Markus; Kalscheuer, Rainer
    The anti-tubercular callyaerins target the Mycobacterium tuberculosis-specific non-essential membrane protein Rv2113
    In: Cell Chemical Biology Vol. 31 (2024) Nr. 10, pp. 1755 - 1771.e73
    Online Full Text: dx.doi.org/ (Open Access)
  • Zheng, Kaijie; Lyu, Joy C.; Thomas, Emma L.; Schuster, Mariana; Sanguankiattichai, Nattapong; Ninck, Sabrina; Kaschani, Farnusch; Kaiser, Markus; van der Hoorn, Renier A. L.
    The proteome of Nicotiana benthamiana is shaped by extensive protein processing
    In: New Phytologist Vol. 243 (2024) Nr. 3, pp. 1034 - 1049
    Online Full Text: dx.doi.org/ (Open Access)
  • Day, Matthew; Tetik, Bilal; Parlak, Milena; Almeida-Hernández, Yasser; Räschle, Markus; Kaschani, Farnusch; Siegert, Heike; Marko, Anika; Sanchez-Garcia, Elsa; Kaiser, Markus; Barker, Isabel A.; Pearl, Laurence H.; Oliver, Antony W.; Boos, Dominik
    TopBP1 utilises a bipartite GINS binding mode to support genome replication
    In: Nature Communications Vol. 15 (2024) Nr. 1, 1797
    Online Full Text: dx.doi.org/; Online Full Text: dx.doi.org/ (Open Access)
  • Merle, David A.; Sen, Merve; Armento, Angela; Stanton, Chloe M.; Thee, Eric F.; Meester-Smoor, Magda A.; Kaiser, Markus; Clark, Simon J.; Klaver, Caroline C.W.; Keane, Pearse A.; Wright, Alan F.; Ehrmann, Michael; Ueffing, Marius
    10q26 – The enigma in age-related macular degeneration
    In: Progress in Retinal and Eye Research Vol. 96 (2023) 101154
    Online Full Text: dx.doi.org/ (Open Access)
  • Ninck, Sabrina; Halder, Vivek; Krahn, Jan; Beisser, Daniela; Resch, Sarah; Dodds, Isobel; Scholtysik, René; Bormann, Jenny; Sewald, Leonard; Gupta, Mainak D.; Heilmann, Geronimo; Bhandari, Deepak D.; Morimoto, Kyoko; Buscaill, Pierre; Hause, Bettina; van der Hoorn, Renier A. L.; Kaschani, Farnusch; Kaiser, Markus
    Chemoproteomics Reveals the Pan-HER Kinase Inhibitor Neratinib To Target an Arabidopsis Epoxide Hydrolase Related to Phytohormone Signaling
    In: ACS Chemical Biology Vol. 18 (2023) Nr. 5, pp. 1076 - 1088
    Online Full Text: dx.doi.org/
  • Hoi, David M.; Junker, Sabryna; Junk, Lukas; Schwechel, Kristin; Fischel, Katharina; Podlesainski, David; Hawkins, Paige M.E.; van Geelen, Lasse; Kaschani, Farnusch; Leodolter, Julia; Morreale, Francesca Ester; Kleine, Stefan; Guha, Somraj; Rumpel, Klaus; Schmiedel, Volker M.; Weinstabl, Harald; Meinhart, Anton; Payne, Richard J.; Kaiser, Markus; Hartl, Markus; Boehmelt, Guido; Kazmaier, Uli; Kalscheuer, Rainer; Clausen, Tim
    Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival
    In: Cell Vol. 186 (2023) Nr. 10, pp. 2176 - 2192.e22
    Online Full Text: dx.doi.org/ (Open Access)
  • Schuster, Mariana; Eisele, Sophie; Armas-Egas, Liz; Kessenbrock, Till; Kourelis, Jiorgos; Kaiser, Markus; van der Hoorn, Renier A. L.
    Enhanced late blight resistance by engineering an EpiC2B-insensitive immune protease
    In: Plant Biotechnology Journal Vol. 22 (2023) Nr. 2, pp. 284 - 286
    Online Full Text: dx.doi.org/ (Open Access)
  • Fehr, Lorenz; Sewald, Leonard; Huber, Robert; Kaiser, Markus
    Facile Multicomponent Synthesis of Oxazolidinones from Primary Amines and Cesium (Hydrogen)Carbonate
    In: European Journal of Organic Chemistry Vol. 26 (2023) Nr. 27, e202300135
    Online Full Text: dx.doi.org/ (Open Access)
  • Andlovic, Blaž; Heilmann, Geronimo; Ninck, Sabrina; Andrei, Sebastian A.; Centorrino, Federica; Higuchi, Yusuke; Kato, Nobuo; Brunsveld, Luc; Arkin, Michelle; Menninger, Sascha; Choidas, Axel; Wolf, Alexander; Klebl, Bert; Kaschani, Farnusch; Kaiser, Markus; Eickhoff, Jan; Ottmann, Christian
    IFNα primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization
    In: Cell Chemical Biology Vol. 30 (2023) Nr. 6, pp. 573 - 590.e6
    Online Full Text: dx.doi.org/
  • Blüggel, Mike; Kröning, Alexander; Kracht, Matthias; van den Boom, Johannes; Dabisch, Matthias; Göhring, Anna; Kaschani, Farnusch; Kaiser, Markus; Bayer, Peter; Meyer, Hemmo; Beuck, Christine
    The UBX domain in UBXD1 organizes ubiquitin binding at the C-terminus of the VCP/p97 AAA-ATPase
    In: Nature Communications Vol. 14 (2023) Nr. 1, 3258
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Kiselev, Andrei; Camborde, Laurent; Carballo, Laura Ossorio; Kaschani, Farnusch; Kaiser, Markus; van der Hoorn, Renier A. L.; Gaulin, Elodie
    The root pathogen Aphanomyces euteiches secretes modular proteases in pea apoplast during host infection
    In: Frontiers in Plant Science (FPLS) Vol. 14 (2023) 1140101
    Online Full Text: dx.doi.org/ (Open Access)
  • Klaus, Thomas; Ninck, Sabrina; Albersmeier, Andreas; Busche, Tobias; Wibberg, Daniel; Jiang, Jianbing; Elcheninov, Alexander G.; Zayulina, Kseniya S.; Kaschani, Farnusch; Bräsen, Christopher; Overkleeft, Herman S.; Kalinowski, Jörn; Kublanov, Ilya V.; Kaiser, Markus; Siebers, Bettina
    Activity-Based Protein Profiling for the Identification of Novel Carbohydrate-Active Enzymes Involved in Xylan Degradation in the Hyperthermophilic Euryarchaeon Thermococcus sp. Strain 2319x1E
    In: Frontiers in Microbiology Vol. 12 (2022) 734039
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Morreale, Francesca E.; Kleine, Stefan; Leodolter, Julia; Junker, Sabryna; Hoi, David M.; Ovchinnikov, Stepan; Okun, Anastasia; Kley, Juliane; Kurzbauer, Robert; Junk, Lukas; Guha, Somraj; Podlesainski, David; Kazmaier, Uli; Boehmelt, Guido; Weinstabl, Harald; Rumpel, Klaus; Schmiedel, Volker M.; Hartl, Markus; Haselbach, David; Meinhart, Anton; Kaiser, Markus; Clausen, Tim
    BacPROTACs mediate targeted protein degradation in bacteria
    In: Cell Vol. 185 (2022) Nr. 13, pp. 2338 - 2353.e18
    Online Full Text: dx.doi.org/ (Open Access)
  • Carvalho, Luís A. R.; Ross, Breyan; Fehr, Lorenz; Bolgi, Oguz; Wöhrle, Svenja; Lum, Kenneth M.; Podlesainski, David; Vieira, Andreia C.; Kiefersauer, Reiner; Félix, Rita; Rodrigues, Tiago; Lucas, Susana D.; Groß, Olaf; Geiss‐Friedlander, Ruth; Cravatt, Benjamin F.; Huber, Robert; Kaiser, Markus; Moreira, Rui
    Chemoproteomics‐Enabled Identification of 4‐Oxo‐β‐Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9
    In: Angewandte Chemie International Edition Vol. 61 (2022) Nr. 47, e202210498
    Online Full Text: dx.doi.org/ (Open Access)
  • Schmerling, Christian; Sewald, Leonard; Heilmann, Geronimo; Witfeld, Frederick; Begerow, Dominik; Jensen, Kenneth; Bräsen, Christopher; Kaschani, Farnusch; Overkleeft, Herman S.; Siebers, Bettina; Kaiser, Markus
    Erratum: Author Correction: Identification of fungal lignocellulose-degrading biocatalysts secreted by Phanerochaete chrysosporium via activity-based protein profiling (Communications biology (2022) 5 1 (1254))
    In: Communications Biology Vol. 5 (2022) Nr. 1, pp. 1319
    Online Full Text: dx.doi.org/ (Open Access)
  • Schmerling, Christian; Sewald, Leonard; Heilmann, Geronimo; Witfeld, Frederick; Begerow, Dominik; Jensen, Kenneth; Bräsen, Christopher; Kaschani, Farnusch; Overkleeft, Herman S.; Siebers, Bettina; Kaiser, Markus
    Identification of fungal lignocellulose-degrading biocatalysts secreted by Phanerochaete chrysosporium via activity-based protein profiling
    In: Communications Biology Vol. 5 (2022) Nr. 1, 1254
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Chauvistré, Heike; Shannan, Batool; Daignault-Mill, Sheena M.; Ju, Robert J.; Picard, Daniel; Egetemaier, Stefanie; Váraljai, Renáta; Gibhardt, Christine S.; Sechi, Antonio; Kaschani, Farnusch; Keminer, Oliver; Stehbens, Samantha J.; Liu, Qin; Yin, Xiangfan; Jeyakumar, Kirujan; Vogel, Felix C. E.; Krepler, Clemens; Rebecca, Vito W.; Kubat, Linda; Lueong, Smiths S.; Forster, Jan; Horn, Susanne; Remke, Marc; Ehrmann, Michael; Paschen, Annette; Becker, Jürgen; Helfrich, Iris; Rauh, Daniel; Kaiser, Markus; Gul, Sheraz; Herlyn, Meenhard; Bogeski, Ivan; Rodríguez-López, José Neptuno; Haass, Nikolas K.; Schadendorf, Dirk; Rösch, Alexander;
    Persister state-directed transitioning and vulnerability in melanoma
    32. Deutscher Hautkrebskongress (ADO-Jahrestagung), 14.–17. September 2022, Hannover, Germany,
    In: Nature Communications Vol. 13 (2022) Nr. 1, pp. 35 - 36
    Online Full Text: dx.doi.org/; Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Abreha, Kibrom B.; Alexandersson, Erik; Resjö, Svante; Lankinen, Åsa; Sueldo, Daniela; Kaschani, Farnusch; Kaiser, Markus; van der Hoorn, Renier A. L.; Levander, Fredrik; Andreasson, Erik
    Article leaf apoplast of field-grown potato analyzed by quantitative proteomics and activity-based protein profiling
    In: International Journal of Molecular Sciences (IJMS) Vol. 22 (2021) Nr. 21, 12033
    Online Full Text: dx.doi.org/ (Open Access)
  • van Geelen, Lasse; Kaschani, Farnusch; Sazzadeh, Shabnam S.; Adeniyi, Emmanuel T.; Meier, Dieter; Proksch, Peter; Pfeffer, Klaus; Kaiser, Markus; Ioerger, Thomas R.; Kalscheuer, Rainer
    Correction to : Natural brominated phenoxyphenols kill persistent and biofilm-incorporated cells of MRSA and other pathogenic bacteria
    In: Applied Microbiology and Biotechnology Vol. 105 (2021) Nr. 14-15, pp. 6119 - 6119
    Online Full Text: dx.doi.org/ (Open Access)
  • Dorsch, Madeleine; Kowalczyk, Manuela; Planque, Mélanie; Heilmann, Geronimo; Urban, Sebastian; Dujardin, Philip; Forster, Jan; Ueffing, Kristina; Nothdurft, Silke; Oeck, Sebastian; Paul, Annika; Liffers, Sven T.; Kaschani, Farnusch; Kaiser, Markus; Schramm, Alexander; Siveke, Jens; Winslow, Monte M.; Fendt, Sarah-Maria; Nalbant, Perihan; Grüner, Barbara M.
    Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis
    In: Cell Reports Vol. 37 (2021) Nr. 8, 110056
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • van den Boom, Johannes; Kück, Anja; Kravic, Bojana; Müschenborn, Helen; Giesing, Maike; Pan, Dongqing; Kaschani, Farnusch; Kaiser, Markus; Musacchio, Andrea; Meyer, Hemmo
    Targeted substrate loop insertion by VCP/p97 during PP1 complex disassembly
    In: Nature Structural & Molecular Biology Vol. 28 (2021) Nr. 12, pp. 964 - 971
    Online Full Text: dx.doi.org/
  • van der Woude, Lennard; Piotrowski, Markus; Klaasse, Gruson; Paulus, Judith K.; Krahn, Daniel; Ninck, Sabrina; Kaschani, Farnusch; Kaiser, Markus; Novák, Ondřej; Ljung, Karin; Bulder, Suzanne; van Verk, Marcel; Snoek, Basten L.; Fiers, Martijn; Martin, Nathaniel I.; van der Hoorn, Renier A. L.; Robert, Stéphanie; Smeekens, Sjef; van Zanten, Martijn
    The chemical compound ‘Heatin’ stimulates hypocotyl elongation and interferes with the Arabidopsis NIT1-subfamily of nitrilases
    In: The Plant Journal Vol. 106 (2021) Nr. 6, pp. 1523 - 1540
    Online Full Text: dx.doi.org/ (Open Access)
  • Smolin, Daniel; Tötsch, Niklas; Grad, Jean-Noël; Linders, Jürgen; Kaschani, Farnusch; Kaiser, Markus; Kirsch, Michael; Hoffmann, Daniel; Schrader, Thomas
    Accelerated trypsin autolysis by affinity polymer templates
    In: RSC Advances Vol. 10 (2020) Nr. 48, pp. 28711 - 28719
    Online Full Text: dx.doi.org/ (Open Access)
  • Smolin, Daniel; Tötsch, Niklas; Grad, Jean-Noël; Linders, Jürgen; Kaschani, Farnusch; Kaiser, Markus; Kirsch, Michael; Hoffmann, Daniel; Schrader, Thomas
    Accelerated trypsin autolysis by affinity polymer templates
    In: RSC Advances Vol. 10 (2020) Nr. 48, pp. 28711 - 28719
    Online Full Text: dx.doi.org/ (Open Access)
  • Merdanovic, Melisa; Burston, Steven G.; Schmitz, Anna Laura; Köcher, Steffen; Knapp, Stefan; Clausen, Tim; Kaiser, Markus; Huber, Robert; Ehrmann, Michael
    Activation by substoichiometric inhibition
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 117 (2020) Nr. 3, pp. 1414 - 1418
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Bach-Pages, Marcel; Homma, Felix; Kourelis, Jiorgos; Kaschani, Farnusch; Mohammed, Shabaz; Kaiser, Markus; van der Hoorn, Renier A. L.; Castello, Alfredo; Preston, Gail M.
    Discovering the RNA-binding proteome of plant leaves with an improved RNA interactome capture method
    In: Biomolecules Vol. 10 (2020) Nr. 4, 661
    Online Full Text: dx.doi.org/ (Open Access)
  • Köcher, Steffen; Resch, Sarah; Kessenbrock, Till; Schrapp, Lukas; Ehrmann, Michael; Kaiser, Markus
    From dolastatin 13 to cyanopeptolins, micropeptins, and lyngbyastatins : the chemical biology of Ahp-cyclodepsipeptides
    In: Natural Product Reports Vol. 37 (2020) Nr. 2, pp. 163 - 174
    Online Full Text: dx.doi.org/
  • van Geelen, Lasse; Kaschani, Farnusch; Sazzadeh, Shabnam S.; Adeniyi, Emmanuel T.; Meier, Dieter; Proksch, Peter; Pfeffer, Klaus; Kaiser, Markus; Ioerger, Thomas R.; Kalscheuer, Rainer
    Natural brominated phenoxyphenols kill persistent and biofilm-incorporated cells of MRSA and other pathogenic bacteria
    In: Applied Microbiology and Biotechnology Vol. 104 (2020) Nr. 13, pp. 5985 - 5998
    Online Full Text: dx.doi.org/ (Open Access)
  • Kracht, Matthias; van den Boom, Johannes; Seiler, Jonas; Kröning, Alexander; Kaschani, Farnusch; Kaiser, Markus; Meyer, Hemmo
    Protein Phosphatase-1 Complex Disassembly by p97 is Initiated through Multivalent Recognition of Catalytic and Regulatory Subunits by the p97 SEP-domain Adapters
    In: Journal of Molecular Biology (JMB) Vol. 432 (2020) Nr. 23, pp. 6061 - 6074
    Online Full Text: dx.doi.org/
  • Sijbesma, Eline; Visser, Emira; Plitzko, Kathrin; Thiel, Philipp; Milroy, Lech-Gustav; Kaiser, Markus; Brunsveld, Luc; Ottmann, Christian
    Structure-based evolution of a promiscuous inhibitor to a selective stabilizer of protein–protein interactions
    In: Nature Communications Vol. 11 (2020) Nr. 1, pp. 3954
    Online Full Text: dx.doi.org/ (Open Access)
  • Göhring, Anna; Michin, Irina; Gerdes, Tina; Schulze, Nina; Blüggel, Mike; Rehic, Edisa; Kaschani, Farnusch; Kaiser, Markus; Bayer, Peter
    Targeting of parvulin interactors by diazirine mediated cross-linking discloses a cellular role of human Par14/17 in actin polymerization
    In: Biological Chemistry Vol. 401 (2020) Nr. 8, pp. 955 - 968
    Online Full Text: dx.doi.org/ (Open Access)
  • Azizan, Asma; Kaschani, Farnusch; Barinas, Hellen; Blaskowski, Svenja; Kaiser, Markus; Denecke, Martin
    Using proteomics for an insight into the performance of activated sludge in a lab-scale WWTP
    In: International Biodeterioration & Biodegradation Vol. 149 (2020) pp. 104934
    Online Full Text: dx.doi.org/
  • Krahn, Daniel; Heilmann, Geronimo; Vogel, Felix C. E.; Papadopoulos, Chrisovalantis; Zweerink, Susanne; Kaschani, Farnusch; Meyer, Hemmo; Rösch, Alexander; Kaiser, Markus
    Zelkovamycin is an OXPHOS Inhibitory Member of the Argyrin Natural Product Family
    In: Chemistry - A European Journal Vol. 26 (2020) Nr. 39, pp. 8524 - 8531
    Online Full Text: dx.doi.org/ (Open Access)
  • Kourelis, Jiorgos; Kaschani, Farnusch; Grosse-Holz, Friederike M.; Homma, Felix; Kaiser, Markus; van der Hoorn, Renier A. L.
    A homology-guided, genome-based proteome for improved proteomics in the alloploid Nicotiana benthamiana
    In: BMC Genomics Vol. 20 (2019) Nr. 1, pp. 722
    Online Full Text: dx.doi.org/ (Open Access)
  • Jutras, Philippe V.; Grosse-Holz, Friederike; Kaschani, Farnusch; Kaiser, Markus; Michaud, Dominique; Hoorn, Renier A. L. van der
    Activity-based proteomics reveals nine target proteases for the recombinant protein-stabilizing inhibitor S/CYS8 in Nicotiana benthamiana
    In: Plant Biotechnology Journal Vol. 17 (2019) Nr. 8, pp. 1670 - 1678
    Online Full Text: dx.doi.org/ (Open Access)
  • Weiss-Sadan, Tommy; Itzhak, Gal; Kaschani, Farnusch; Yu, Zhanru; Mahameed, Mohamed; Anaki, Adi; Ben-Nun, Yael; Merquiol, Emmanuelle; Tirosh, Boaz; Kessler, Benedikt; Kaiser, Markus; Blum, Galia
    Cathepsin L regulates metabolic networks controlling rapid cell growth and proliferation
    In: Molecular and Cellular Proteomics (MCP) Vol. 18 (2019) Nr. 7, pp. 1330 - 1344
    Online Full Text: dx.doi.org/ (Open Access)
  • Weiss-Sadan, Tommy; Maimoun, David; Oelschlagel, Diana; Kaschani, Farnusch; Misiak, Danny; Gaikwad, Hanmant; Ben-Nun, Yael; Merquiol, Emmanuelle; Anaki, Adi; Tsvirkun, Darya; Kaiser, Markus; Michl, Patrick; Gotsman, Israel; Blum, Galia
    Cathepsins Drive Anti-Inflammatory Activity by Regulating Autophagy and Mitochondrial Dynamics in Macrophage Foam Cells
    In: Cellular Physiology and Biochemistry Vol. 53 (2019) Nr. 3, pp. 550 - 572
    Online Full Text: dx.doi.org/ (Open Access)
  • Bongard, Jens; Schmitz, Anna Laura; Wolf, Alex; Zischinsky, Gunther; Pieren, Michel; Schellhorn, Birgit; Bravo-Rodriguez, Kenny; Schillinger, Jasmin; Koch, Uwe; Nussbaumer, Peter; Klebl, Bert; Steinmann, Jörg; Buer, Jan; Sánchez-García, Elsa; Ehrmann, Michael; Kaiser, Markus
    Chemical Validation of DegS As a Target for the Development of Antibiotics with a Novel Mode of Action
    In: ChemMedChem Vol. 14 (2019) Nr. 11, pp. 1074 - 1078
    Online Full Text: dx.doi.org/
  • Viñegra de la Torre, Natanael; Kaschani, Farnusch; Kaiser, Markus; van der Hoorn, Renier A L; Soppe, Wim J J; Misas Villamil, Johana C.
    Dynamic hydrolase labelling as a marker for seed quality in Arabidopsis seeds
    In: Biochemical Journal Vol. 476 (2019) Nr. 5, pp. 843 - 857
    Online Full Text: dx.doi.org/ (Open Access)
  • Buscaill, Pierre; Chandrasekar, Balakumaran; Sanguankiattichai, Nattapong; Kourelis, Jiorgos; Kaschani, Farnusch; Thomas, Emma L.; Morimoto, Kyoko; Kaiser, Markus; Preston, Gail M.; Ichinose, Yuki; Van Der Hoorn, Renier A.L.
    Glycosidase and glycan polymorphism control hydrolytic release of immunogenic flagellin peptides
    In: Science Vol. 364 (2019) Nr. 6436, eaav0748
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Kraiselburd, Ivana; Brüls, Thomas; Heilmann, Geronimo; Kaschani, Farnusch; Kaiser, Markus; Meckenstock, Rainer
    Metabolic reconstruction of the genome of candidate Desulfatiglans TRIP_1 and identification of key candidate enzymes for anaerobic phenanthrene degradation
    In: Environmental Microbiology Vol. 21 (2019) Nr. 4, pp. 1267 - 1286
    Online Full Text: dx.doi.org/ (Open Access)
  • Halder, Vivek; Suliman, Mohamed N S; Kaschani, Farnusch; Kaiser, Markus
    Plant chemical genetics reveals colistin sulphate as a SA and NPR1-independent PR1 inducer functioning via a p38-like kinase pathway
    In: Scientific Reports Vol. 9 (2019) Nr. 1, pp. 11196
    Online Full Text: dx.doi.org/ (Open Access)
  • Schulze Hüynck, Jan; Kaschani, Farnusch; van der Linde, Karina; Ziemann, Sebastian; Müller, André N.; Colby, Thomas; Kaiser, Markus; Misas Villamil, Johana C.; Doehlemann, Gunther
    Proteases underground : Analysis of the maize root apoplast identifies organ specific papain-like cysteine protease activity
    In: Frontiers in Plant Science (FPLS) Vol. 10 (2019)
    Online Full Text: dx.doi.org/ (Open Access)
  • Morimoto, Kyoko; Cole, Kyle S.; Kourelis, Jiorgos; Witt, Collin H.; Brown, Daniel; Krahn, Daniel; Stegmann, Monika; Kaschani, Farnusch; Kaiser, Markus; Burton, Jonathan; Mohammed, Shabaz; Yamaguchi-Shinozaki, Kazuko; Weerapana, Eranthie; van der Hoorn, Renier A. L.
    Triazine probes target ascorbate peroxidases in plants
    In: Plant Physiology Vol. 180 (2019) Nr. 4, pp. 1848 - 1859
    Online Full Text: dx.doi.org/ (Open Access)
  • Pöhler, Robert; Krahn, Jan; van den Boom, Johannes; Dobrynin, Grzegorz; Kaschani, Farnusch; Eggenweiler, Hans-Michael; Zenke, Frank T.; Kaiser, Markus; Meyer, Hemmo
    A Non-Competitive Inhibitor of VCP/p97 and VPS4 Reveals Conserved Allosteric Circuits in Type I and II AAA ATPases
    In: Angewandte Chemie International Edition Vol. 57 (2018) Nr. 6, pp. 1576 - 1580
    Online Full Text: dx.doi.org/
  • Ziemann, Sebastian; Van Der Linde, Karina; Lahrmann, Urs; Acar, Beyda; Kaschani, Farnusch; Colby, Tom; Kaiser, Markus; Ding, Yezhang; Schmelz, Eric; Huffaker, Alisa; Holton, Nicholas; Zipfel, Cyril; Doehlemann, Gunther
    An apoplastic peptide activates salicylic acid signalling in maize
    In: Nature Plants Vol. 4 (2018) Nr. 3, pp. 172 - 180
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Dong, Xiyang; Greening, Chris; Brüls, Thomas; Conrad, Ralf; Guo, Kun; Blaskowski, Svenja; Kaschani, Farnusch; Kaiser, Markus; Abu Laban, Nidal; Meckenstock, Rainer
    Fermentative Spirochaetes mediate necromass recycling in anoxic hydrocarbon-contaminated habitats
    In: ISME Journal Vol. 12 (2018) Nr. 8, pp. 2039 - 2050
    Online Full Text: dx.doi.org/ (Open Access)
  • Schillinger, Jasmin; Severin, Katharina; Kaschani, Farnusch; Kaiser, Markus; Ehrmann, Michael
    HTRA1-Dependent Cell Cycle Proteomics
    In: Journal of Proteome Research Vol. 17 (2018) Nr. 8, pp. 2679 - 2694
    Online Full Text: dx.doi.org/
  • Bongard, Jens; Lorenz, Marian; Vetter, Ingrid R.; Stege, Patricia; Porfetye, Arthur T.; Schmitz, Anna Laura; Kaschani, Farnusch; Wolf, Alex; Koch, Uwe; Nussbaumer, Peter; Klebl, Bert; Kaiser, Markus; Ehrmann, Michael
    Identification of Noncatalytic Lysine Residues from Allosteric Circuits via Covalent Probes
    In: ACS Chemical Biology Vol. 13 (2018) Nr. 5, pp. 1307 - 1312
    Online Full Text: dx.doi.org/
  • Halder, Vivek; Oeljeklaus, Julian; Heilmann, Geronimo; Krahn, Jan; Liu, Yanlin; Xiong, Yan; Schlicht, Markus; Schillinger, Jasmin; Kracher, Barbara; Ehrmann, Michael; Kombrink, Erich; Kaschani, Farnusch; Kaiser, Markus
    Identification of the Natural Product RotihibinA as a TOR Kinase Signaling Inhibitor by Unbiased Transcriptional Profiling
    In: Chemistry - A European Journal Vol. 24 (2018) Nr. 48, pp. 12500 - 12504
    Online Full Text: dx.doi.org/
  • Santos, Rita B.; Chandrasekar, Balakumaran; Mandal, Manoj K.; Kaschani, Farnusch; Kaiser, Markus; Both, Leonard; van der Hoorn, Renier A. L.; Schiermeyer, Andreas; Abranches, Rita
    Low Protease Content in Medicago truncatula Cell Cultures Facilitates Recombinant Protein Production
    In: Biotechnology Journal Vol. 13 (2018) Nr. 7, 1800050
    Online Full Text: dx.doi.org/
  • Yilmaz, Elvan; Bier, David; Guillory, Xavier; Briels, Jeroen; Ruiz-Blanco, Yasser B.; Sánchez-García, Elsa; Ottmann, Christian; Kaiser, Markus
    Mono- and Bivalent 14-3-3 Inhibitors for Characterizing Supramolecular “Lysine Wrapping” of Oligoethylene Glycol (OEG) Moieties in Proteins
    In: Chemistry - A European Journal (2018)
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Husaini, Amjad M; Morimoto, Kyoko; Chandrasekar, Balakumaran; Kelly, Steven; Kaschani, Farnusch; Palmero, Daniel; Jiang, Jianbing; Kaiser, Markus; Ahrazem, Oussama; Overkleeft, Hermen S; van der Hoorn, Renier A L
    Multiplex Fluorescent, Activity-Based Protein Profiling Identifies Active α-Glycosidases and Other Hydrolases in Plants
    In: Plant Physiology Vol. 177 (2018) Nr. 1, pp. 24 - 37
    Online Full Text: dx.doi.org/ (Open Access)
  • Planas-Marquès, Marc; Bernardo-Faura, Martí; Paulus, Judith; Kaschani, Farnusch; Kaiser, Markus; Valls, Marc; Van Der Hoorn, Renier A. L.; Coll, Núria S.
    Protease Activities Triggered by Ralstonia solanacearum Infection in Susceptible and Tolerant Tomato Lines
    In: Molecular and Cellular Proteomics (MCP) Vol. 17 (2018) Nr. 6, pp. 1112 - 1125
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Grosse-Holz, Friederike; Kelly, Steven; Blaskowski, Svenja; Kaschani, Farnusch; Kaiser, Markus; van der Hoorn, Renier A.L.
    The transcriptome, extracellular proteome and active secretome of agroinfiltrated Nicotiana benthamiana uncover a large, diverse protease repertoire
    In: Plant Biotechnology Journal Vol. 16 (2018) Nr. 5, pp. 1068 - 1084
    Online Full Text: dx.doi.org/ (Open Access)
  • Grosse-Holz, Friederike; Madeira, Luisa; Zahid, Muhammad Awais; Songer, Molly; Kourelis, Jiorgos; Fesenko, Mary; Ninck, Sabrina; Kaschani, Farnusch; Kaiser, Markus; van der Hoorn, Renier A.L.
    Three unrelated protease inhibitors enhance accumulation of pharmaceutical recombinant proteins in Nicotiana benthamiana
    In: Plant Biotechnology Journal Vol. 16 (2018) Nr. 10, pp. 1797 - 1810
    Online Full Text: dx.doi.org/ (Open Access)
  • Weith, Matthias; Seiler, Jonas; van den Boom, Johannes; Kracht, Matthias; Hülsmann, Julia; Primorac, Ivana; Del Pino Garcia, Javier; Kaschani, Farnusch; Kaiser, Markus; Musacchio, Andrea; Bollen, Mathieu; Meyer, Hemmo
    Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation
    In: Molecular Cell Vol. 72 (2018) Nr. 4, pp. 766 - 777
    Online Full Text: dx.doi.org/ (Open Access)
  • Bravo-Rodriguez, Kenny; Hagemeier, Birte; Drescher, Lea; Lorenz, Marian; Rey, Juliana; Meltzer, Michael; Kaschani, Farnusch; Kaiser, Markus; Ehrmann, Michael
    Utilities for Mass Spectrometry Analysis of Proteins (UMSAP) : Fast post-processing of mass spectrometry data
    In: Rapid Communications in Mass Spectrometry Vol. 32 (2018) Nr. 19, pp. 1659 - 1667
    Online Full Text: dx.doi.org/
  • Zweerink, Susanne; Kallnik, Verena; Ninck, Sabrina; Nickel, Sabrina; Verheyen, Julia; Blum, Marcel; Wagner, Alexander; Feldmann, Ingo; Sickmann, Albert; Albers, Sonja-Verena; Bräsen, Christopher; Kaschani, Farnusch; Siebers, Bettina; Kaiser, Markus
    Activity-based protein profiling as a robust method for enzyme identification and screening in extremophilic Archaea
    In: Nature Communications Vol. 8 (2017) pp. 15352
    Online Full Text: dx.doi.org/ (Open Access)
  • Klein, Diana; Steens, Jennifer; Wiesemann, Alina; Schulz, Florian; Kaschani, Farnusch; Röck, Katharina; Yamaguchi, Masahiro; Wirsdörfer, Florian; Kaiser, Markus; Fischer, Jens W.; Stuschke, Martin; Jendrossek, Verena
    Mesenchymal stem cell therapy protects lungs from radiation-induced endothelial cell loss by restoring superoxide dismutase 1 expression
    In: Antioxidants and Redox Signaling Vol. 26 (2017) Nr. 11, pp. 563 - 582
    Online Full Text: dx.doi.org/ (Open Access)
  • Kovács, Judit; Poór, Péter; Kaschani, Farnusch; Chandrasekar, Balakumaran; Hong, Tram N.; Misas-Villamil, Johana C.; Xin, Bo T.; Kaiser, Markus; Overkleeft, Herman S.; Tari, Irma; van der Hoorn, Renier A. L.
    Proteasome activity profiling uncovers alteration of catalytic β2 and β5 subunits of the stress-induced proteasome during salinity stress in tomato roots
    In: Frontiers in Plant Science (FPLS) Vol. 8 (2017) 107
    Online Full Text: dx.doi.org/ (Open Access)
  • Beisser, Daniela; Kaschani, Farnusch; Graupner, Nadine; Großmann, Lars; Jensen, Manfred; Ninck, Sabrina; Schulz, Florian; Rahmann, Sven; Boenigk, Jens; Kaiser, Markus
    Quantitative proteomics reveals ecophysiological effects of light and silver stress on the mixotrophic protist Poterioochromonas malhamensis
    In: PLoS ONE Vol. 12 (2017) Nr. 1, pp. e0168183
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Ehrmann, Michael; Kaiser, Markus
    Small Molecules from Deep within the Gut
    In: ChemBioChem Vol. 18 (2017) Nr. 11, pp. 967 - 968
    Online Full Text: dx.doi.org/
  • Misas-Villamil, Johana C.; van der Burgh, Aranka M.; Grosse-Holz, Friederike; Bach-Pages, Marcel; Kovács, Judit; Kaschani, Farnusch; Schilasky, Sören; Emon, Asif E.K.; Ruben, Mark; Kaiser, Markus; Overkleeft, Hermen S.; van der Hoorn, Renier A.L.
    Subunit-selective proteasome activity profiling uncovers uncoupled proteasome subunit activities during bacterial infections
    In: The Plant Journal Vol. 90 (2017) Nr. 2, pp. 418 - 430
    Online Full Text: dx.doi.org/
  • Köcher, Steffen; Rey, Juliana; Bongard, Jens; Tiaden, André N.; Meltzer, Michael; Richards, Peter J.; Ehrmann, Michael; Kaiser, Markus
    Tailored Ahp-cyclodepsipeptides as Potent Non-covalent Serine Protease Inhibitors
    In: Angewandte Chemie International Edition Vol. 56 (2017) Nr. 29, Special Issue: 100th Anniversary of the Royal Australian Chemical Institute, pp. 8555 - 8558
    Online Full Text: dx.doi.org/
  • De Montaigu, Amaury; Oeljeklaus, Julian; Krahn, Jan; Suliman, Mohamed N.S.; Halder, Vivek; De Ansorena, Elisa; Nickel, Sabrina; Schlicht, Markus; Plíhal, Ondřej; Kubiasová, Karolina; Radová, Lenka; Kracher, Barbara; Tóth, Réka; Kaschani, Farnusch; Coupland, George; Kombrink, Erich; Kaiser, Markus
    The Root Growth-Regulating Brevicompanine Natural Products Modulate the Plant Circadian Clock
    In: ACS Chemical Biology Vol. 12 (2017) Nr. 6, pp. 1466 - 1471
    Online Full Text: dx.doi.org/ (Open Access)
  • Krahn, Jan; Kaschani, Farnusch; Kaiser, Markus
    Turning-ON Proteasomes
    In: Cell Chemical Biology Vol. 24 (2017) Nr. 6, pp. 653 - 655
    Online Full Text: dx.doi.org/
  • Shaulov-Rotem, Yulia; Merquiol, Emmanuelle; Weiss-Sadan, Tommy; Moshel, Ofra; Salpeter, Seth; Shabat, Doron; Kaschani, Farnusch; Kaiser, Markus; Blum, Galia
    A novel quenched fluorescent activity-based probe reveals caspase-3 activity in the endoplasmic reticulum during apoptosis
    In: Chemical Science Vol. 7 (2016) pp. 1322 - 1337
    Online Full Text: dx.doi.org/ (Open Access)
  • Kaschani, Farnusch; Wei, Quing; Dingemans, Jozef; van der Hoorn, Renier A.L.; Cornelis, Pierre; Kaiser, Markus
    Capture of endogenously biotinylated proteins from Pseudomonas aeruginosa displays unexpected downregulation of LiuD upon iron nutrition
    In: Bioorganic and Medicinal Chemistry Vol. 24 (2016) Nr. 15, pp. 3330 - 3335
    Online Full Text: dx.doi.org/
  • van den Boom, Johannes; Wolf, Markus; Weimann, Lena; Schulze, Nina; Li, Fanghua; Kaschani, Farnusch; Riemer, Anne; Zierhut, Christian; Kaiser, Markus; Iliakis, George; Funabiki, Hironori; Meyer, Hemmo
    VCP/p97 Extracts Sterically Trapped Ku70/80 Rings from DNA in Double-Strand Break Repair
    In: Molecular Cell Vol. 64 (2016) Nr. 1, pp. 189 - 198
    Online Full Text: dx.doi.org/ (Open Access)
  • Ehrmann, Michael; Kaschani, Farnusch; Kaiser, Markus
    Chemical proteomics versus Leishmaniasis
    In: Chemistry and Biology Vol. 22 (2015) Nr. 3, pp. 309 - 310
    Online Full Text: dx.doi.org/ (Open Access)
  • Nickel, Sabrina; Serwa, Remigiusz A.; Kaschani, Farnusch; Ninck, Sabrina; Zweerink, Susanne; Tate, Edward W.; Kaiser, Markus
    Chemoproteomic Evaluation of the Polyacetylene Callyspongynic Acid
    In: Chemistry - A European Journal Vol. 21 (2015) Nr. 30, pp. 10721 - 10728
    Online Full Text: dx.doi.org/ (Open Access)
  • Poepsel, Simon; Sprengel, Andreas; Sacca, Barbara; Kaschani, Farnusch; Kaiser, Markus; Gatsogiannis, Christos; Raunser, Stefan; Clausen, Tim; Ehrmann, Michael
    Determinants of amyloid fibril degradation by the PDZ protease HTRA1
    In: Nature Chemical Biology Vol. 11 (2015) Nr. 11, pp. 862 - 869
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Ilyas, Muhammad; Hörger, Anja C.; Bozkurt, Tolga O.; Burg, Harrold A. van den; Kaschani, Farnusch; Kaiser, Markus; Belhaj, Khaoula; Smoker, Matthew; Joosten, Matthieu H. A. J.; Kamoun, Sophien; Hoorn, Renier A. L. van der
    Functional divergence of two secreted immune proteases of tomato
    In: Current Biology Vol. 25 (2015) Nr. 17, pp. 2300 - 2306
    Online Full Text: dx.doi.org/ (Open Access)
  • Kellermann, Guillaume; Kaiser, Markus; Dingli, Florent; Lahuna, Olivier; Naud-Martin, Delphine; Mahuteau-Betzer, Florence; Loew, Damarys; Ségal-Bendirdjian, Évelyne; Teulade-Fichou, Marie-Paule; Bombard, Sophie
    Identification of human telomerase assembly inhibitors enabled by a novel method to produce hTERT
    In: Nucleic Acids Research Vol. 43 (2015) Nr. 15, art. no. e99
    Online Full Text: dx.doi.org/ (Open Access)
  • Lu, Haibin; Chandrasekar, Balakumaran; Oeljeklaus, Julian; Misas-Villamil, Johana C.; Wang, Zheming; Shindo, Takayuki; Bogyo, Matthew; Kaiser, Markus; van der Hoorn, Renier A. L.
    Subfamily-specific fluorescent probes for cysteine proteases display dynamic protease activities during seed germination
    In: Plant Physiology Vol. 168 (2015) Nr. 4, pp. 1462 - 1475
    Online Full Text: dx.doi.org/
  • Nickel, Sabrina; Nickel, Philipp; Hellmert, Marco; Ernst, Silvia; Jewell, Robert; Pearce, Christopher A.; Jones, Geraint; Hamza, Daniel; Kaiser, Markus
    Synthesis of a hexahydropyrrolo indole (HPI) compound library
    In: Bioorganic and Medicinal Chemistry Vol. 23 (2015) Nr. 11, pp. 2636 - 2645
    Online Full Text: dx.doi.org/
  • Meesters, Christian; Mönig, Timon; Oeljeklaus, Julian; Krahn, Daniel; Westfall, Corey S.; Hause, Bettina; Jez, Joseph M; Kaiser, Markus; Kombrink, Erich
    A chemical inhibitor of jasmonate signaling targets JAR1 in Arabidopsis thaliana
    In: Nature Chemical Biology Vol. 10 (2014) Nr. 10, pp. 830 - 836
    Online Full Text: dx.doi.org/
  • Köhn, Maja; Meijler, Michael M.; Kaiser, Markus
    Building up a chemical proteomics network in Europe and beyond
    In: ACS Chemical Biology Vol. 9 (2014) Nr. 8, pp. 1647 - 1648
    Online Full Text: dx.doi.org/
  • van den Boom, Johannes; Mamic, Marija; Baccelliere, Daniele; Zweerink, Susanne; Kaschani, Farnusch; Knauer, Shirley; Bayer, Peter; Kaiser, Markus
    Peptidyl succinimidyl peptides as taspase 1 inhibitors
    In: ChemBioChem Vol. 15 (2014) Nr. 15, pp. 2233 - 2237
    Online Full Text: dx.doi.org/
  • Bruss, Hanna; Schuster, Hannah; Martinez, Rémi; Kaiser, Markus; Antonchick, Andrey P.; Waldmann, Herbert
    Synthesis of the B-seco limonoid core scaffold
    In: Beilstein Journal of Organic Chemistry Vol. 10 (2014) pp. 194 - 208
    Online Full Text: dx.doi.org/ (Open Access)
  • Lu, Haibin; Wang, Zheming; Shabab, Mohammed; Oeljeklaus, Julian; Verhelst, Steven H.; Kaschani, Farnusch; Kaiser, Markus; Bogyo, Matthew; Hoorn, Renier A. L. van der
    A substrate-inspired probe monitors translocation, activation, and subcellular targeting of bacterial type III effector protease AvrPphB
    In: Chemistry and Biology Vol. 20 (2013) Nr. 2, pp. 168 - 176
    Online Full Text: dx.doi.org/
  • Stolze, Sara C.; Meltzer, Michael; Ehrmann, Michael; Kaiser, Markus
    Ahp cyclodepsipeptides: The impact of the ahp residue on the "Canonical Inhibition" of S1 serine proteases
    In: ChemBioChem Vol. 14 (2013) Nr. 11, pp. 1301 - 1308
    Online Full Text: dx.doi.org/
  • Stolze, Sara C.; Kaiser, Markus
    Case studies of the synthesis of bioactive cyclodepsipeptide natural products
    In: Molecules: A Journal of Synthetic Chemistry and Natural Product Chemistry Vol. 18 (2013) Nr. 2, pp. 1337 - 1367
    Online Full Text: dx.doi.org/ (Open Access)
  • Gu, Christian; Shannon, D. Alexander; Colby, Tom; Wang, Zheming; Shabab, Mohammed; Kumari, Selva; Villamor, Joji Grace; McLaughlin, Christopher J.; Weerapana, Eranthie; Kaiser, Markus; Cravatt, Benjamin F.; Van Der Hoorn, Renier A.L.
    Chemical proteomics with sulfonyl fluoride probes reveals selective labeling of functional tyrosines in glutathione transferases
    In: Chemistry and Biology Vol. 20 (2013) Nr. 4, pp. 541 - 548
    Online Full Text: dx.doi.org/ (Open Access)
  • Merdanovic, Melisa; Mönig, Timon; Ehrmann, Michael; Kaiser, Markus
    Diversity of allosteric regulation in proteases
    In: ACS Chemical Biology Vol. 8 (2013) Nr. 1, pp. 19 - 26
    Online Full Text: dx.doi.org/
  • Villamor, Joji Grace; Kaschani, Farnusch; Colby, Tom; Oeljeklaus, Julian; Zhao, David; Kaiser, Markus; Patricelli, Matthew P.; Van Der Hoorn, Renier A. L.
    Profiling protein kinases and other ATP binding proteins in arabidopsis using acyl-ATP probes
    In: Molecular and Cellular Proteomics (MCP) Vol. 12 (2013) Nr. 9, pp. 2481 - 2496
    Online Full Text: dx.doi.org/
  • Misas-Villamil, Johana C.; Kolodziejek, Izabella; Crabill, Emerson; Kaschani, Farnusch; Niessen, Sherry; Shindo, Takayuki; Kaiser, Markus; Alfano, James R.; van der Hoorn, Renier A. L.
    Pseudomonas syringae pv. syringae Uses Proteasome Inhibitor Syringolin A to Colonize from Wound Infection Sites
    In: PLoS Pathogens Vol. 9 (2013) Nr. 3, pp. e1003281
    Online Full Text: dx.doi.org/ (Open Access)
  • Oeljeklaus, Julian; Kaschani, Farnusch; Kaiser, Markus
    Streamlining chemical probe discovery : libraries of "fully functionalized" small molecules for phenotypic screening
    In: Angewandte Chemie International Edition Vol. 52 (2013) Nr. 5, pp. 1368 - 1370
    Online Full Text: dx.doi.org/
  • Nickel, Sabrina; Kaschani, Farnusch; Colby, Tom; Van Der Hoorn, Renier A.L.; Kaiser, Markus
    A para-nitrophenol phosphonate probe labels distinct serine hydrolases of Arabidopsis
    In: Bioorganic and Medicinal Chemistry Vol. 20 (2012) Nr. 2, pp. 601 - 606
    Online Full Text: dx.doi.org/
  • Archer, Crystal R; Groll, Michael; Stein, Martin L; Schellenberg, Barbara; Clerc, Jérôme; Kaiser, Markus; Kondratyuk, Tamara P; Pezzuto, John M; Dudler, Robert; Bachmann, André S.
    Activity enhancement of the synthetic syrbactin proteasome inhibitor hybrid and biological evaluation in tumor cells
    In: Biochemistry Vol. 51 (2012) Nr. 34, pp. 6880 - 6888
    Online Full Text: dx.doi.org/
  • Bier, Carolin; Knauer, Shirley; Wünsch, Désirée; Kunst, Lena; Scheiding, Sabine; Kaiser, Markus; Ottmann, Christian; Krämer, Oliver H.; Stauber, Roland H.
    Allosteric inhibition of Taspase1's pathobiological activity by enforced dimerization in vivo
    In: The FASEB Journal Vol. 26 (2012) Nr. 8, pp. 3421 - 3429
    Online Full Text: dx.doi.org/
  • Stolze, Sara C.; Kaiser, Markus
    Challenges in the syntheses of peptidic natural products
    In: Synthesis: Journal of Synthetic Organic Chemistry Vol. 44 (2012) Nr. 12, pp. 1755 - 1777
    Online Full Text: dx.doi.org/
  • Weski, Juliane; Meltzer, Michael; Spaan, Lina; Mönig, Timon; Oeljeklaus, Julian; Hauske, Patrick; Vouilleme, Lars; Volkmer, Rudolf; Boisguerin, Prisca; Boyd, Dana; Huber, Robert; Kaiser, Markus; Ehrmann, Michael
    Chemical Biology Approaches Reveal Conserved Features of a C-Terminal Processing PDZ Protease
    In: ChemBioChem Vol. 13 (2012) Nr. 3, pp. 402 - 408
    Online Full Text: dx.doi.org/
  • Stolze, Sara Christina; Meltzer, Michael; Ehrmann, Michael; Kaiser, Markus
    Development of a Solid-Phase Approach to the Natural Product Class of Ahp-Containing Cyclodepsipeptides
    In: European Journal of Organic Chemistry (2012) Nr. 8, pp. 1616 - 1625
    Online Full Text: dx.doi.org/
  • Van Der Linden, Wouter A.; Willems, Lianne I.; Shabaneh, Tamer B.; Li, Nan; Ruben, Mark; Florea, Bogdan I.; Van Der Marel, Gijs A.; Kaiser, Markus; Kisselev, Alexei F.; Overkleeft, Herman S.
    Discovery of a potent and highly β1 specific proteasome inhibitor from a focused library of urea-containing peptide vinyl sulfones and peptide epoxyketones
    In: Organic and Biomolecular Chemistry Vol. 10 (2012) Nr. 1, pp. 181 - 194
    Online Full Text: dx.doi.org/
  • Lütticke, Christiane; Hauske, Patrick; Lewandrowski, Urs; Sickmann, Albert; Kaiser, Markus; Ehrmann, Michael
    E. coli LoiP (YggG), a metalloprotease hydrolyzing Phe–Phe bonds
    In: Molecular BioSystems Vol. 8 (2012) Nr. 6, pp. 1775 - 1782
    Online Full Text: dx.doi.org/ Online Full Text
  • Tennstaedt, Annette; Pöpsel, Simon; Trübestein, Linda; Hauske, Patrick; Brockmann, Anke; Schmidt, Nina; Irle, Inga; Sacca, Barbara; Niemeyer, Christof M.; Brandt, Roland; Ksiezak-Reding, Hanna; Tirniceriu, Anca Laura; Egensperger, Rupert; Baldi, Alfonso; Dehmelt, Leif; Kaiser, Markus; Huber, Robert; Clausen, Tim; Ehrmann, Michael
    Human high temperature requirement serine protease A1 (HTRA1) degrades tau protein aggregates
    In: The Journal of Biological Chemistry (JBC) Vol. 287 (2012) Nr. 25, pp. 20931 - 20941
    Online Full Text: dx.doi.org/
  • Kaschani, Farnusch; Clerc, Jérôme; Krahn, Daniel; Bier, David; Hong, Tram Ngoc; Ottmann, Christian; Niessen, Sherry; Colby, Tom; Van Der Hoorn, Renier A. L.; Kaiser, Markus; van der Hoorn, Renier A. L.
    Identification of a selective, activity-based probe for glyceraldehyde 3-phosphate dehydrogenases
    In: Angewandte Chemie International Edition Vol. 51 (2012) Nr. 21, pp. 5230 - 5233
    Online Full Text: dx.doi.org/
  • Kaiser, Markus; Ottmann, Christian
    In Silico Identification of an Interferon Inhibitor
    In: ChemMedChem Vol. 7 (2012) Nr. 4, pp. 555 - 557
    Online Full Text: dx.doi.org/
  • Stein, Martin L.; Beck, Philipp; Kaiser, Markus; Dudler, Robert; Becker, Christian F. W.; Groll, Michael
    One-shot NMR analysis of microbial secretions identifies highly potent proteasome inhibitor
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 109 (2012) Nr. 45, pp. 18367 - 18371
    Online Full Text: dx.doi.org/
  • van der Hoorn, Renier A. L.; Kaiser, Markus
    Probes for activity-based profiling of plant proteases
    In: Physiologia Plantarum Vol. 145 (2012) Nr. 1, Special Issue: Plant Proteases, pp. 18 - 27
    Online Full Text: dx.doi.org/
  • Kaschani, Farnusch; Nickel, Sabrina; Pandey, Bikram; Cravatt, Benjamin F.; Kaiser, Markus; Van Der Hoorn, Renier A.L.
    Selective inhibition of plant serine hydrolases by agrochemicals revealed by competitive ABPP
    In: Bioorganic and Medicinal Chemistry Vol. 20 (2012) Nr. 2, pp. 597 - 600
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Thiel, Philipp; Kaiser, Markus; Ottmann, Christian
    Small-molecule stabilization of protein-protein interactions : An underestimated concept in drug discovery?
    In: Angewandte Chemie International Edition Vol. 51 (2012) Nr. 9, pp. 2012 - 2018
    Online Full Text: dx.doi.org/
  • Shannon, D. Alexander; Gu, Christian; Mclaughlin, Christopher J.; Kaiser, Markus; van der Hoorn, Renier A. L.; Weerapana, Eranthie
    Sulfonyl Fluoride Analogues as Activity-Based Probes for Serine Proteases
    In: ChemBioChem Vol. 13 (2012) Nr. 16, pp. 2327 - 2330
    Online Full Text: dx.doi.org/
  • Stolze, Sara Christina; Deu, Edgar; Kaschani, Farnusch; Li, Nan; Florea, Bogdan I.; Richau, Kerstin H.; Colby, Tom; Van Der Hoorn, Renier A.L.; Overkleeft, Hermen S.; Bogyo, Matthew; Kaiser, Markus
    The antimalarial natural product symplostatin 4 is a nanomolar inhibitor of the food vacuole falcipains
    In: Chemistry and Biology Vol. 19 (2012) Nr. 12, pp. 1546 - 1555
    Online Full Text: dx.doi.org/
  • Ottmann, Christian; Van Der Hoorn, Renier A. L.; Kaiser, Markus
    The impact of plant-pathogen studies on medicinal drug discovery
    In: Chemical Society Reviews Vol. 41 (2012) Nr. 8, pp. 3168 - 3178
    Online Full Text: dx.doi.org/
  • Wuest, William M.; Krahn, Daniel; Kaiser, Markus; Walsh, Christopher T.
    Enzymatic timing and tailoring of macrolactamization in syringolin biosynthesis
    In: Organic Letters Vol. 13 (2011) Nr. 17, pp. 4518 - 4521
    Online Full Text: dx.doi.org/
  • Clausen, Tim; Kaiser, Markus; Huber, Robert; Ehrmann, Michael
    HTRA proteases : regulated proteolysis in protein quality control
    In: Nature Reviews Molecular Cell Biology Vol. 12 (2011) Nr. 3, pp. 152 - 162
    Online Full Text: dx.doi.org/
  • Krahn, D.; Ottmann, C.; Kaiser, Markus
    Macrocyclic Proteasome Inhibitors
    In: Current Medicinal Chemistry Vol. 18 (2011) Nr. 33, pp. 5052 - 5060
    Online Full Text: dx.doi.org/
  • Van der Hoorn, Renier A.L.; Colby, Tom; Nickel, Sabrina; Richau, Kerstin H.; Schmidt, Jürgen; Kaiser, Markus
    Mining the active proteome of Arabidopsis Thaliana
    In: Frontiers in Plant Science (FPLS) Vol. 2 (2011) 89
    Online Full Text: dx.doi.org/ (Open Access)
  • Kolodziejek, Izabella; Misas-Villamil, Johana C.; Kaschani, Farnusch; Clerc, Jérôme; Gu, Christian; Krahn, Daniel; Niessen, Sherry; Verdoes, Martijn; Willems, Lianne I.; Overkleeft, Hermen S.; Kaiser, Markus; van der Hoorn, Renier A. L.
    Proteasome activity imaging and profiling characterizes bacterial effector Syringolin A
    In: Plant Physiology Vol. 155 (2011) Nr. 1, pp. 477 - 489
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Merdanovic, Melisa; Clausen, Tim; Kaiser, Markus; Huber, Robert; Ehrmann, Michael
    Protein quality control in the bacterial periplasm
    In: Annual Review of Microbiology Vol. 65 (2011) pp. 149 - 168
    Online Full Text: dx.doi.org/
  • Trübestein, Linda; Tennstaedt, Annette; Mönig, Timon; Krojer, Tobias; Canellas, Flavia; Kaiser, Markus; Clausen, Tim; Ehrmann, Michael
    Substrate induced remodeling of the active site regulates human HtrA1 activity
    In: Nature Structural & Molecular Biology Vol. 18 (2011) pp. 386 - 388
    Online Full Text: dx.doi.org/
  • Schuster, Hannah; Martinez, Rémi; Bruss, Hanna; Antonchick, Andrey P.; Kaiser, Markus; Schürmann, Markus; Waldmann, Herbert
    Synthesis of the B-seco limonoid scaffold
    In: Chemical Communications: ChemComm Vol. 47 (2011) Nr. 23, pp. 6545 - 6547
    Online Full Text: dx.doi.org/
  • Krahn, Daniel; Ottmann, Christian; Kaiser, Markus
    The chemistry and biology of syringolins, glidobactins and cepafungins (syrbactins)
    In: Natural Product Reports Vol. 28 (2011) Nr. 11, pp. 1854 - 1867
    Online Full Text: dx.doi.org/
  • Clerc, Jérôme; Li, Nan; Krahn, Daniel; Groll, Michael; Bachmann, André S; Florea, Bogdan I; Overkleeft, Herman S; Kaiser, Markus
    The natural product hybrid of Syringolin A and Glidobactin A synergizes proteasome inhibition potency with subsite selectivity.
    In: Chemical Communications: ChemComm Vol. 47 (2011) Nr. 1, pp. 385 - 387
    Online Full Text: dx.doi.org/
  • Cottier, Stéphanie; Mönig, Timon; Wang, Zheming; Svoboda, Jiří; Boland, Wilhelm; Kaiser, Markus; Kombrink, Erich
    The yeast three-hybrid system as an experimental platform to identify proteins interacting with small signaling molecules in plant cells : Potential and limitations
    In: Frontiers in Plant Science (FPLS) Vol. 2 (2011) Nr. DEC, 101
    Online Full Text: dx.doi.org/ (Open Access)
  • Wetzel, Stefan; Wilk, Wolfram; Chammaa, Samy; Sperl, Bianca; Roth, Anke G.; Yektaoglu, Aybike; Renner, Steffen; Berg, Thorsten; Arenz, Christoph; Giannis, Athanassios; Oprea, Tudor I.; Rauh, Daniel; Kaiser, Markus; Waldmann, Herbert
    A Scaffold-Tree-Merging Strategy for Prospective Bioactivity Annotation of γ-Pyrones
    In: Angewandte Chemie International Edition Vol. 49 (2010) Nr. 21, pp. 3666 - 3670
    Online Full Text: dx.doi.org/
  • Ottmann, Christian; Hauske, Patrick; Kaiser, Markus
    Activation Instead of Inhibition : Targeting Proenzymes for Small-Molecule Intervention
    In: ChemBioChem Vol. 11 (2010) Nr. 5, pp. 637 - 639
    Online Full Text: dx.doi.org/ Online Full Text
  • Clerc, Jérôme; Schellenberg, Barbara; Groll, Michael; Bachmann, André S.; Huber, Robert; Dudler, Robert; Kaiser, Markus
    Convergent synthesis and biological evaluation of syringolin a and derivatives as eukaryotic 20S proteasome inhibitors
    In: European Journal of Organic Chemistry (2010) Nr. 21, pp. 3991 - 4003
    Online Full Text: dx.doi.org/
  • Hasenbein, Sonja; Meltzer, Michael; Hauske, Patrick; Kaiser, Markus; Huber, Robert; Clausen, Tim; Ehrmann, Michael
    Conversion of a regulatory into a degradative protease
    In: Journal of Molecular Biology (JMB) Vol. 397 (2010) Nr. 4, pp. 957 - 966
    Online Full Text: dx.doi.org/
  • Merdanovic, Melisa; Mamant, Nicolette; Meltzer, Michael; Poepsel, Simon; Auckenthaler, Alexandra; Melgaard, Rie; Hauske, Patrick; Nagel-Steger, Luitgard; Clarke, Anthony R.; Kaiser, Markus; Huber, Robert; Ehrmann, Michael
    Determinants of structural and functional plasticity of a widely conserved protease chaperone complex
    In: Nature Structural & Molecular Biology Vol. 17 (2010) Nr. 7, pp. 837 - 843
    Online Full Text: dx.doi.org/
  • Molzan, Manuela; Schumacher, Benjamin; Ottmann, Corinna; Baljuls, Angela; Polzien, Lisa; Weyand, Michael; Thiel, Philipp; Rose, Rolf; Rose, Micheline; Kuhenne, Philipp; Kaiser, Markus; Rapp, Ulf R.; Kuhlmann, Jürgen; Ottmann, Christian
    Impaired Binding of 14-3-3 to C-RAF in Noonan Syndrome Suggests New Approaches in Diseases with Increased Ras Signaling
    In: Molecular and Cellular Biology (MCB) Vol. 30 (2010) Nr. 19, pp. 4698 - 4711
    Online Full Text: dx.doi.org/
  • Kim, Sung Soo; Grienenberger, Etienne; Lallemand, Benjamin; Colpitts, Che C.; Kim, Sun Young; de Azevedo Souza, Clarice; Geoffroy, Pierrette; Heintz, Dimitri; Krahn, Daniel; Kaiser, Markus; Kombrink, Erich; Heitz, Thierry; Suh, Dae-Yeon; Legrand, Michel; Douglas, Carl J.
    LAP6/POLYKETIDE SYNTHASE A and LAP5/POLYKETIDE SYNTHASE B encode hydroxyalkyl α-pyrone synthases required for pollen development and sporopollenin biosynthesis in Arabidopsis thaliana
    In: The Plant Cell Vol. 22 (2010) Nr. 12, pp. 4045 - 4066
    Online Full Text: dx.doi.org/ (Open Access)
  • Imker, Heidi J.; Krahn, Daniel; Clerc, Jérôme; Kaiser, Markus; Walsh, Christopher T.
    N-Acylation during glidobactin biosynthesis by the tridomain nonribosomal peptide synthetase module GlbF
    In: Chemistry and Biology Vol. 17 (2010) Nr. 10, pp. 1077 - 1083
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Wilk, Wolfram; Zimmermann, Tobias J.; Kaiser, Markus; Waldmann, Herbert
    Principles, implementation, and application of biology-oriented synthesis (BIOS).
    In: Biological Chemistry Vol. 391 (2010) Nr. 5, pp. 491 - 497
    Online Full Text
  • Stolze, Sara Christina; Meltzer, Michael; Ehrmann, Michael; Kaiser, Markus
    Solid phase total synthesis of the 3-amino-6-hydroxy-2-piperidone (Ahp) cyclodepsipeptide and protease inhibitor Symplocamide A
    In: Chemical Communications: ChemComm (2010) Nr. 46, pp. 8857 - 8859
    Online Full Text: dx.doi.org/
  • Archer, Crystal R.; Koomoa, Dana-Lynn T.; Mitsunaga, Erin M.; Clerc, Jérôme; Shimizu, Mariko; Kaiser, Markus; Schellenberg, Barbara; Dudler, Robert; Bachmann, André S.
    Syrbactin class proteasome inhibitor-induced apoptosis and autophagy occurs in association with p53 accumulation and Akt/PKB activation in neuroblastoma
    In: Biochemical Pharmacology Vol. 80 (2010) Nr. 2, pp. 170 - 178
    Online Full Text: dx.doi.org/
  • Kaiser, Markus; Ottmann, Christian
    The first small-molecule inhibitor of 14-3-3s : Modulating the master regulator
    In: ChemBioChem Vol. 11 (2010) Nr. 15, pp. 2085 - 2087
    Online Full Text: dx.doi.org/
  • Wilk, Wolfram; Nören-Müller, Andrea; Kaiser, Markus; Waldmann, Herbert
    Biology-Oriented Combined Solid- and Solution-Phase Synthesis of a Macroline-Like Compound Collection
    In: Chemistry - A European Journal Vol. 15 (2009) Nr. 44, pp. 11976 - 11984
    Online Full Text: dx.doi.org/
  • Kaschani, Farnusch; Verhelst, Steven H. L.; van Swieten, Paul F.; Verdoes, Martijn; Wong, Chung-Sing; Wang, Zheming; Kaiser, Markus; Overkleeft, Herman S.; Bogyo, Matthew; van der Hoorn, Renier A.L.
    Minitags for small molecules: detecting targets of reactive small molecules in living plant tissues using ‘click chemistry’.
    In: The Plant Journal Vol. 57 (2009) Nr. 2, pp. 373 - 385
    Online Full Text
  • Hauske, Patrick; Mamant, Nicolette; Hasenbein, Sonja; Nickel, Sabrina; Ottmann, Christian; Clausen, Tim; Ehrmann, Michael; Kaiser, Markus
    Peptidic small molecule activators of the stress sensor DegS
    In: Molecular BioSystems Vol. 5 (2009) Nr. 9, pp. 980 - 985
    Online Full Text: dx.doi.org/
  • Rose, Rolf; Huttenlocher, Franziska; Cedzich, Anna; Kaiser, Markus; Schaller, Andreas; Ottmann, Christian
    Purification, crystallization and preliminary X-ray diffraction analysis of a plant subtilase.
    In: Acta crystallographica, Section F, Structural biology and crystallization communications online Vol. 65 (2009) Nr. 5, pp. 522 - 525
    Online Full Text
  • Hauske, Patrick; Meltzer, Michael; Ottmann, Christian; Krojer, Tobias; Clausen, Tim; Ehrmann, Michael; Kaiser, Markus
    Selectivity profiling of DegP substrates and inhibitors
    In: Bioorganic and Medicinal Chemistry Vol. 17 (2009) Nr. 7, pp. 2920 - 2924
    Online Full Text: dx.doi.org/
  • Ottmann, Christian; Rose, Rolf; Huttenlocher, Franziska; Cedzich, Anna; Hauske, Patrick; Kaiser, Markus; Huber, Robert; Schaller, Andreas
    Structural basis for Ca2+-independence and activation by homodimerization of tomato subtilase 3
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 106 (2009) Nr. 40, pp. 17223 - 17228
    Online Full Text: dx.doi.org/
  • Meltzer, Michael; Hasenbein, Sonja; Mamant, Nicolette; Merdanovic, Melisa; Poepsel, Simon; Hauske, Patrick; Kaiser, Markus; Huber, Robert; Krojer, Tobias; Clausen, Tim; Ehrmann, Michael
    Structure, function and regulation of the conserved serine proteases DegP and DegS of Escherichia coli
    In: Research in Microbiology Vol. 160 (2009) Nr. 9, pp. 660 - 666
    Online Full Text: dx.doi.org/
  • Clerc, Jérôme; Groll, Michael; Illich, Damir J.; Bachmann, André S.; Huber, Robert; Schellenberg, Barbara; Dudler, Robert; Kaiser, Markus
    Synthetic and structural studies on Syringolin A and B reveal critical determinants for selectivity and potency of proteasome inhibition
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 106 (2009) Nr. 16, pp. 6507 - 6512
    Online Full Text
  • Clerc, Jérôme; Florea, Bogdan I.; Kraus, Marianne; Groll, Michael; Huber, Robert; Bachmann, André S.; Dudler, Robert; Driessen, Christoph; Overkleeft, Herman S.; Kaiser, Markus
    Syringolin A selectively labels the 20S proteasome in murine EL4 and wildtype and bortezomib adapted leukemic cell lines
    In: ChemBioChem Vol. 10 (2009) Nr. 16, pp. 2638 - 2643
    Online Full Text: dx.doi.org/ Online Full Text
  • Knoth, Tanja; Warburg, Karin; Katzka, Catherine; Rai, Amrita; Wolf, Alexander; Brockmeyer, Andreas; Janning, Petra; Reubold, Thomas F.; Eschenburg, Susanne; Manstein, Dietmar J.; Hübel, Katja; Kaiser, Markus; Waldmann, Herbert; Manstein, Dietmar J.
    The ras pathway modulator melophlin a targets dynamins
    In: Angewandte Chemie International Edition Vol. 48 (2009) Nr. 39, pp. 7240 - 7245
    Online Full Text: dx.doi.org/; Online Full Text: dx.doi.org/
  • Yoshida, Masahito; Hedberg, Christian; Kaiser, Markus; Waldmann, Herbert
    Traceless solid phase synthesis of natural product inspired cis-1,2-dehydrodecalins
    In: Chemical Communications: ChemComm (2009) Nr. 20, pp. 2923 - 2925
    Online Full Text: dx.doi.org/
  • Wilk, Wolfram; Waldmann, Herbert; Kaiser, Markus
    γ-Pyrone natural products – a privileged compound class provided by nature.
    In: Bioorganic & medicinal chemistry : a Tetrahedron publication for the rapid dissemination of full original research papers and critical reviews on biomolecular chemistry, medicinal chemistry and related disciplines Vol. 17 (2009) Nr. 6, pp. 2304 - 2309
  • Groll, Michael; Schellenberg, Barbara; Bachmann, André S.; Archer, Crystal R.; Huber, Robert; Powell, Tracy K.; Lindow, Steven; Kaiser, Markus; Dudler, Robert
    A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism
    In: Nature Vol. 452 (2008) pp. 755 - 758
    Online Full Text
  • Meltzer, Michael; Hasenbein, Sonja; Hauske, Patrick; Kucz, Nicolette; Merdanovic, Melisa; Grau, Sandra; Beil, Alexandra; Jones, Dafydd; Krojer, Tobias; Clausen, Tim; Ehrmann, Michael; Kaiser, Markus
    Allosteric activation of HtrA protease DegP by stress signals during bacterial protein quality control
    In: Angewandte Chemie International Edition Vol. 47 (2008) Nr. 7, pp. 1332 - 1334
    Online Full Text: dx.doi.org/
  • Hauske, Patrick; Otmann, Christian; Meltzer, Michael; Ehrmann, Michael; Kaiser, Markus
    Allosteric regulation of proteases
    In: ChemBioChem Vol. 9 (2008) Nr. 18, pp. 2920 - 2928
    Online Full Text: dx.doi.org/ Online Full Text
  • Kaiser, Markus; Wetzel, Stefan; Kumar, K.; Waldmann, Herbert
    Biology-inspired synthesis of compound libraries
    In: Cellular and Molecular Life Sciences - CMLS Vol. 65 (2008) Nr. 7/8, pp. 1186 - 1201
    Online Full Text
  • Nören-Müller, Andrea; Wilk, Wolfram; Krishna, Saxena; Schwalbe, Harald; Kaiser, Markus; Waldmann, Herbert
    Discovery of a New Class of Inhibitors of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B by Biology-Oriented Synthesis
    In: Angewandte Chemie International Edition Vol. 47 (2008) Nr. 32, pp. 5973 - 5977
    Online Full Text: dx.doi.org/
  • Bachmann, André S.; Archer, Crystal R.; Schellenberg, Barbara; Kaiser, Markus; Groll, Michael; Dudler, Robert
    Identification and characterization of a novel proteasome inhibitor with apoptotic properties in neuroblastoma.
    In: Proceedings : annual meeting of the American Association for Cancer Research. Vol. 49 (2008) pp. 773
  • Amrane, Samir; De Cian, Anne; Rosu, Frédéric; Kaiser, Markus; De Pauw, Edwin; Teulade-Fichou, Marie-Paule; Mergny, Jean-Louis
    Identification of CNG trinucleotide repeat ligands with a FRET melting assay
    In: ChemBioChem Vol. 9 (2008) Nr. 8, pp. 1229 - 1234
    Online Full Text: dx.doi.org/ Online Full Text
  • Schneider, Katja; Wang, Zheming; Kaiser, Markus; Kombrink, Erich
    On the molecular mechanism of hormone action: Hunting the jasmonate target(s)
    In: Current topics in phytochemistry Vol. 9 (2008) pp. 1 - 16
  • Wang, Zheming; Gu, Christian; Colby, Tom; Shindo, Takayuki; Balamurugan, Rengarajan; Waldmann, Herbert; Kaiser, Markus; van der Hoorn, Renier A.L.
    β-lactone probes identify a papain-like peptide ligase in Arabidopsis thaliana.
    In: Nature Chemical Biology Vol. 4 (2008) Nr. 9, pp. 557 - 563
    Online Full Text
  • De Cian, Anne; Guittat, Lionel; Kaiser, Markus; Sacca, Barbara; Amrane, Samir; Bourdoncle, Anne; Alberti, Patrizia; Teulade-Fichou, Marie-Paule; Lacroix, Laurent; Mergny, Jean-Louis
    Fluorescence-based melting assays for studying quadruplex ligands
    In: Methods: A Companion to Methods in Enzymology Vol. 42 (2007) Nr. 2, pp. 183 - 195
    Online Full Text: dx.doi.org/
  • Corrêa, Ivan R.; Nören-Müller, Andrea; Ambrosi, Horst-Dieter; Jakupovic, Sven; Saxena, Krishna; Schwalbe, Harald; Kaiser, Markus; Waldmann, Herbert
    Identification of inhibitors for mycobacterial protein tyrosine phosphatase B (MptpB) by biology-oriented synthesis (BIOS).
    In: Chemistry: An Asian Journal Vol. 2 (2007) Nr. 9, pp. 1109 - 1126
    Online Full Text
  • Kaiser, Markus; Sainlos, Matthieu; Lehn, Jean-Marie; Bombard, Sophie; Teulade-Fichou, Marie-Paule
    Aminoglycoside-quinacridine conjugates : Towards recognition of the P6.1 element of Telomerase RNA.
    In: ChemBioChem Vol. 7 (2006) Nr. 2, pp. 321 - 329
    Online Full Text: dx.doi.org/ Online Full Text
  • Kaiser, Markus; De Cian, Anne; Sainlos, Matthieu; Renner, Christian; Mergny, Jean-Louis; Teulade-Fichou, Marie-Paule
    Neomycin-capped aromatic platforms : Quadruplex DNA recognition and telomerase inhibition
    In: Organic and Biomolecular Chemistry Vol. 4 (2006) Nr. 6, pp. 1049 - 1057
    Online Full Text: dx.doi.org/
  • Groll, Michael; Götz, Marion; Kaiser, Markus; Weyher, Elisabeth; Moroder, Luis
    TMC-95-Based Inhibitor Design Provides Evidence for the Catalytic Versatility of the Proteasome
    In: Chemistry and Biology Vol. 13 (2006) Nr. 6, pp. 607 - 614
    Online Full Text
  • Musiol, Hans-Jürgen; Dong, Shouliang; Kaiser, Markus; Bausinger, Ralf; Zumbusch, Andreas; Bertsch, Uwe; Moroder, Luis
    Toward Semisynthetic Lipoproteins by Convergent Strategies Based on Click and Ligation Chemistry
    In: ChemBioChem Vol. 6 (2005) Nr. 4, pp. 625 - 628
    Online Full Text: dx.doi.org/ Online Full Text
  • Kaiser, Markus; Groll, Michael; Siciliano, Carlo; Assfalg-Machleidt, Irmgard; Weyher, Elisabeth; Kohno, Jun; Milbradt, Alexander G.; Renner, Christian; Huber, Robert; Moroder, Luis
    Binding mode of TMC-95A analogues to eukaryotic 20S proteasome
    In: ChemBioChem Vol. 5 (2004) Nr. 9, pp. 1256 - 1266
    Online Full Text: dx.doi.org/
  • Kaiser, Markus; Milbradt, Alexander G.; Sicilianoa, Carlo; Assfalg-Machleidt, Irmgard; Machleidt, Werner; Groll, Michael; Renner, Christian; Moroder, Luis
    TMC-95A analogues with endocyclic biphenyl ether group as proteasome inhibitors.
    In: Chemistry & biodiversity : CB ; an official journal of the Center for the Study of Biological Complexity Vol. 1 (2004) Nr. 1, pp. 161 - 173
    Online Full Text
  • Kaiser, Markus; Siciliano, Carlo; Assfalg-Machleidt, Irmgard; Groll, Michael; Milbradt, Alexander G.; Moroder, Luis
    Synthesis of a TMC-95A ketomethylene analogue by cyclization via intramolecular Suzuki coupling.
    In: Organic Letters Vol. 5 (2003) Nr. 19, pp. 3435 - 3437
    Online Full Text
  • Kim, Jeong-Sun; Groll, Michael; Musiol, Hans-Jürgen; Behrendt, Raymond; Kaiser, Markus; Moroder, Luis; Huber, Robert; Brandstetter, Hans
    Navigation inside a protease: Substrate selection and product exit in the tricorn protease from Thermoplasma acidophilum
    In: Journal of Molecular Biology (JMB) Vol. 324 (2002) Nr. 5, pp. 1041 - 1050
    Online Full Text: dx.doi.org/
  • Ashcroft, Alison E.; Brinker, Achim; Coyle, Joseph E.; Weber, Frank; Kaiser, Markus; Moroder, Luis; Parsons, Mark R.; Jager, Joachim; Hartl, Ulrich F.; Hayer-Hartl, Manajit; Radford, Sheena E.
    Structural plasticity and non-covalent substrate binding in the GroEL apical domain: A study using electrospray ionisation mass spectrometry and fluorescence binding studies
    In: The Journal of Biological Chemistry (JBC) Vol. 277 (2002) Nr. 36, pp. 33115 - 33126
    Online Full Text
  • Kaiser, Markus; Milbradt, Alexander G.; Moroder, Luis
    Structure-based prediction of cyclization propensities of linear precursors
    In: International Journal of Peptide Research and Therapeutics Vol. 9 (2002) Nr. 2/3, pp. 65 - 70
    Online Full Text
  • Kaiser, Markus; Milbradt, Alexander G.; Moroder, Luis
    Synthesis of TMC-95A analogues. Structure-based prediction of cyclization propensities of linear precursors
    In: Letters in Peptide Science Vol. 9 (2002) Nr. 2-3, pp. 65 - 70
    Online Full Text: dx.doi.org/
  • Kaiser, Markus; Groll, Michael; Renner, Christian; Huber, Robert; Moroder, Luis
    The Core Structure of TMC-95A Is a Promising Lead for Reversible Proteasome Inhibition
    In: Angewandte Chemie International Edition Vol. 41 (2002) Nr. 5, pp. 780 - 783
    Online Full Text: dx.doi.org/
Patents

Groll M, Kaiser M, Huber R, Moroder L, Renner C, Kohno J. Crystals of a Proteasome-Inhibitor Complex. Patent WO02081501 (2002).

Kaiser M, Clerc J. Development of a synthesis of Syringolin A and B and derivatives thereof. Patent US 61/129,865 (2008).

Kaiser M, Clerc J. Derivatives of syringolin A. Patent EP09075018.3-2117 (2009).

*Please note: The data privacy settings related to this external link are subject to the respective third-party's privacy policies, terms and conditions: Elsevier.