Research
The Kaiser group develops and uses chemical biology approaches to investigate diverse aspects of regulated proteolysis and to study the molecular mechanisms behind bioactive small molecule action. Our interests are however not limited to basic research; rather, we aim to capitalize on our scientific findings for drug discovery or other medicinal applications.
Research Projects
EFRE/JTF Project ClearView: New strategies to fight AMD
The aim of the project is to profile inhibitors developed by the consortium for the protease HTRA1 in order to demonstrate target-mediated activity with patient samples and animal models of age-related macular degeneration and thus pave the way for application.
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DFG CRC 1430 Molecular Mechanisms on Cell State Transitions
B01: Developing chemical tools for investigating cell state transitions