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Ehrmann, Michael
The Periplasm
Washington, DC (2006) XVIII, 415 S., [11] Bl. : Ill., graph. Darst.
ISBN: 1-55581-398-4; 978-1-55581-398-7
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Activation by substoichiometric inhibitionIn: Proceedings of the National Academy of Sciences of the United States of America Vol. 117 (2020) Nr. 3, pp. 1414 - 1418
ISSN: 1091-6490; 0027-8424Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
Tailored Ahp-cyclodepsipeptides as Potent Non-covalent Serine Protease InhibitorsIn: Angewandte Chemie International Edition Vol. 56 (2017) Nr. 29, Special Issue: 100th Anniversary of the Royal Australian Chemical Institute, pp. 8555 - 8558
ISSN: 1521-3773; 1433-7851Online Full Text: dx.doi.org/ -
Determinants of amyloid fibril degradation by the PDZ protease HTRA1In: Nature Chemical Biology Vol. 11 (2015) Nr. 11, pp. 862 - 869
ISSN: 1552-4450; 1552-4469Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
Cerebral small vessel disease-related protease HtrA1 processes latent TGF-β binding protein 1 and facilitates TGF-β signalingIn: Proceedings of the National Academy of Sciences of the United States of America Vol. 111 (2014) Nr. 46, pp. 16496 - 16501
ISSN: 1091-6490; 0027-8424Online Full Text: dx.doi.org/ -
Newly folded substrates inside the molecular cage of the HtrA chaperone DegQIn: Nature Structural & Molecular Biology Vol. 19 (2012) Nr. 2, pp. 152 - 157
ISSN: 1545-9993Online Full Text: dx.doi.org/ -
HTRA proteases : regulated proteolysis in protein quality controlIn: Nature Reviews Molecular Cell Biology Vol. 12 (2011) Nr. 3, pp. 152 - 162
ISSN: 1471-0072Online Full Text: dx.doi.org/ -
Protein quality control in the bacterial periplasmIn: Annual Review of Microbiology Vol. 65 (2011) pp. 149 - 168
ISSN: 1545-3251; 0066-4227Online Full Text: dx.doi.org/ -
Structural adaptation of the plant protease Deg1 to repair photosystem II during light exposureIn: Nature Structural & Molecular Biology Vol. 18 (2011) Nr. 6, pp. 728 - 731
ISSN: 1545-9993Online Full Text: dx.doi.org/ -
Substrate induced remodeling of the active site regulates human HtrA1 activityIn: Nature Structural & Molecular Biology Vol. 18 (2011) pp. 386 - 388
ISSN: 1545-9993Online Full Text: dx.doi.org/ -
Determinants of structural and functional plasticity of a widely conserved protease chaperone complexIn: Nature Structural & Molecular Biology Vol. 17 (2010) Nr. 7, pp. 837 - 843
ISSN: 1545-9993; 1545-9985Online Full Text: dx.doi.org/ -
Allosteric activation of HtrA protease DegP by stress signals during bacterial protein quality controlIn: Angewandte Chemie International Edition Vol. 47 (2008) Nr. 7, pp. 1332 - 1334
ISSN: 0044-8249; 0932-2140Online Full Text: dx.doi.org/ -
Interplay of PDZ and protease domain of DegP ensures efficient elimination of misfolded proteinsIn: Proceedings of the National Academy of Sciences of the United States of America Vol. 22 (2008) pp. 7702 - 7707
ISSN: 1091-6490; 0027-8424 -
Structural basis for the regulated protease and chaperone function of DegP.In: Nature (2008) Nr. 453, pp. 885 - 890
ISSN: 0028-0836; 1476-4687 -
Regulation of the σE stress response by DegS: How the PDZ domain keeps the protease inactive in the resting state and allows integration of different OMP-derived stress signals upon folding stressIn: Genes and Development Vol. 21 (2007) Nr. 20, pp. 2659 - 2670
ISSN: 0890-9369; 1549-5477Online Full Text: dx.doi.org/ -
Implications of human HtrA1 in amyloid precursor protein processing.In: Proceedings of the National Academy of Sciences of the United States of America Vol. 102 (2005) Nr. 17, pp. 6021 - 6026
ISSN: 1091-6490; 0027-8424 -
Implications of the serine protease HtrA1 in amyloid precursor protein processingIn: Proceedings of the National Academy of Sciences of the United States of America Vol. 102 (2005) Nr. 17, pp. 6021 - 6026
ISSN: 1091-6490; 0027-8424 -
Target-directed proteolysis at the ribosome.In: Proceedings of the National Academy of Sciences of the United States of America Vol. 102 (2005) pp. 4246 - 4251
ISSN: 1091-6490; 0027-8424 -
Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a proteaseIn: Cell Vol. 117 (2004) Nr. 4, pp. 483 - 494
ISSN: 0092-8674 -
Proteolysis as a regulatory mechanismIn: Annual Review of Genetics Vol. 38 (2004) pp. 709 - 724
ISSN: 0066-4170; 0066-4197 -
SecA-dependent quality control of intracellular protein localizationIn: Proceedings of the National Academy of Sciences of the United States of America Vol. 100 (2003) Nr. 23, pp. 13231 - 13234
ISSN: 1091-6490; 0027-8424 -
Crystal structure of DegP (HtrA) reveals a new protease-chaperone machineIn: Nature Vol. 416 (2002) Nr. 6879, pp. 455 - 459
ISSN: 0028-0836; 1476-4687 -
The HtrA family of proteases: Implications for protein composition and cell fateIn: Molecular Cell Vol. 10 (2002) Nr. 3, pp. 443 - 455
ISSN: 1097-2765 -
A temperature-dependent switch from chaperone to protease in a widely conserved heat shock proteinIn: Cell Vol. 97 (1999) Nr. 3, pp. 339 - 347
ISSN: 0092-8674 -
TnTIN and TnTAP: Mini-transposons for site-specific proteolysis in vivoIn: Proceedings of the National Academy of Sciences of the United States of America Vol. 94 (1997) Nr. 24, pp. 13111 - 13115
ISSN: 1091-6490; 0027-8424 -
Genetic analysis of membrane protein topology by a sandwich gene fusion approach.In: Proceedings of the National Academy of Sciences of the United States of America Vol. 87 (1990) Nr. 19, pp. 7574 - 7578
ISSN: 1091-6490; 0027-8424
Journal articles
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High resolution analysis of proteolytic substrate processingIn: The Journal of Biological Chemistry (JBC) Vol. 300 (2024) Nr. 11, 107812Online Full Text: dx.doi.org/ (Open Access)
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Rational correction of pathogenic conformational defects in HTRA1In: Nature Communications Vol. 15 (2024) Nr. 1, 5944Online Full Text: dx.doi.org/ (Open Access)
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10q26 – The enigma in age-related macular degenerationIn: Progress in Retinal and Eye Research Vol. 96 (2023) 101154Online Full Text: dx.doi.org/ (Open Access)
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A Single Residue within the MCR-1 Protein Confers Anticipatory ResilienceIn: Microbiology Spectrum Vol. 11 (2023) Nr. 3, e03592-22Online Full Text: dx.doi.org/ (Open Access)
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An allosteric HTRA1-calpain 2 complex with restricted activation profileIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 119 (2022) Nr. 14, e2113520119Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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PPI-Affinity : A Web Tool for the Prediction and Optimization of Protein-Peptide and Protein-Protein Binding AffinityIn: Journal of Proteome Research Vol. 21 (2022) Nr. 8, pp. 1829 - 1841Online Full Text: dx.doi.org/ (Open Access)
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Persister state-directed transitioning and vulnerability in melanomaIn: Nature Communications Vol. 13 (2022) Nr. 1, 3055Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Whole-exome sequencing reveals a role of HTRA1 and EGFL8 in brain white matter hyperintensitiesIn: Brain: A Journal of Neurology Vol. 144 (2021) Nr. 9, pp. 2670 - 2682Online Full Text: dx.doi.org/ (Open Access)
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Activation by substoichiometric inhibitionIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 117 (2020) Nr. 3, pp. 1414 - 1418Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Adoption of a Turn Conformation Drives the Binding Affinity of p53 C-Terminal Domain Peptides to 14-3-3σIn: ACS Chemical Biology Vol. 15 (2020) Nr. 1, pp. 262 - 271Online Full Text: dx.doi.org/ (Open Access)
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From dolastatin 13 to cyanopeptolins, micropeptins, and lyngbyastatins : the chemical biology of Ahp-cyclodepsipeptidesIn: Natural Product Reports Vol. 37 (2020) Nr. 2, pp. 163 - 174Online Full Text: dx.doi.org/
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Supramolecular Mechanism of Viral Envelope Disruption by Molecular TweezersIn: Journal of the American Chemical Society: JACS Vol. 142 (2020) Nr. 40, pp. 17024 - 17038Online Full Text: dx.doi.org/ (Open Access)
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Chemical Validation of DegS As a Target for the Development of Antibiotics with a Novel Mode of ActionIn: ChemMedChem Vol. 14 (2019) Nr. 11, pp. 1074 - 1078Online Full Text: dx.doi.org/
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Native Top-Down Mass Spectrometry and Ion Mobility Spectrometry of the Interaction of Tau Protein with a Molecular Tweezer Assembly ModulatorIn: Journal of the American Society for Mass Spectrometry (JASMS) Vol. 30 (2019) Nr. 1, pp. 16 - 23Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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The ubiquitin-conjugating enzyme UBE2QL1 coordinates lysophagy in response to endolysosomal damageIn: EMBO Reports (2019) pp. e48014Online Full Text: dx.doi.org/ (Open Access)
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HTRA1-Dependent Cell Cycle ProteomicsIn: Journal of Proteome Research Vol. 17 (2018) Nr. 8, pp. 2679 - 2694Online Full Text: dx.doi.org/
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Identification of Noncatalytic Lysine Residues from Allosteric Circuits via Covalent ProbesIn: ACS Chemical Biology Vol. 13 (2018) Nr. 5, pp. 1307 - 1312Online Full Text: dx.doi.org/
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Identification of the Natural Product RotihibinA as a TOR Kinase Signaling Inhibitor by Unbiased Transcriptional ProfilingIn: Chemistry - A European Journal Vol. 24 (2018) Nr. 48, pp. 12500 - 12504Online Full Text: dx.doi.org/
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Inactivation of the serine protease HTRA1 inhibits tumor growth by deregulating angiogenesisIn: Oncogene Vol. 37 (2018) pp. 4260 - 4272Online Full Text: dx.doi.org/
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Utilities for Mass Spectrometry Analysis of Proteins (UMSAP) : Fast post-processing of mass spectrometry dataIn: Rapid Communications in Mass Spectrometry Vol. 32 (2018) Nr. 19, pp. 1659 - 1667Online Full Text: dx.doi.org/
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Small Molecules from Deep within the GutIn: ChemBioChem Vol. 18 (2017) Nr. 11, pp. 967 - 968Online Full Text: dx.doi.org/
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Tailored Ahp-cyclodepsipeptides as Potent Non-covalent Serine Protease InhibitorsIn: Angewandte Chemie International Edition Vol. 56 (2017) Nr. 29, Special Issue: 100th Anniversary of the Royal Australian Chemical Institute, pp. 8555 - 8558Online Full Text: dx.doi.org/
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Tailored protein encapsulation into a DNA host using geometrically organized supramolecular interactionsIn: Nature Communications Vol. 8 (2017) pp. 14472Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Uptake of the proteins HTRA1 and HTRA2 by cells mediated by calcium phosphate nanoparticlesIn: Beilstein Journal of Nanotechnology Vol. 8 (2017) Nr. 1, pp. 381 - 393Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagyIn: The EMBO Journal Vol. 36 (2017) Nr. 2, pp. 135 - 150Online Full Text: dx.doi.org/ (Open Access)
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Epigenetic silencing of serine protease HTRA1 drives polyploidyIn: BMC Cancer Vol. 16 (2016) Nr. 1,Online Full Text: dx.doi.org/ (Open Access)
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Chemical proteomics versus LeishmaniasisIn: Chemistry and Biology Vol. 22 (2015) Nr. 3, pp. 309 - 310Online Full Text: dx.doi.org/ (Open Access)
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Determinants of amyloid fibril degradation by the PDZ protease HTRA1In: Nature Chemical Biology Vol. 11 (2015) Nr. 11, pp. 862 - 869Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Reply to Liu et al. : Loss of TGF-β signaling in CARASIL pathogenesisIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 112 (2015) Nr. 14, pp. E1694Online Full Text: dx.doi.org/
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Cerebral small vessel disease-related protease HtrA1 processes latent TGF-β binding protein 1 and facilitates TGF-β signalingIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 111 (2014) Nr. 46, pp. 16496 - 16501Online Full Text: dx.doi.org/
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Substrate occupancy at the onset of oligomeric transitions of DegPIn: Structure Vol. 22 (2014) Nr. 2, pp. 281 - 290Online Full Text: dx.doi.org/ (Open Access)
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Ahp cyclodepsipeptides: The impact of the ahp residue on the "Canonical Inhibition" of S1 serine proteasesIn: ChemBioChem Vol. 14 (2013) Nr. 11, pp. 1301 - 1308Online Full Text: dx.doi.org/
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Diversity of allosteric regulation in proteasesIn: ACS Chemical Biology Vol. 8 (2013) Nr. 1, pp. 19 - 26Online Full Text: dx.doi.org/
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Identification of a serine protease inhibitor which causes inclusion vacuole reduction and is lethal to Chlamydia trachomatisIn: Molecular Microbiology Vol. 89 (2013) Nr. 4, pp. 676 - 689Online Full Text: dx.doi.org/
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XCtpB assembles a gated protease tunnel regulating cell-cell signaling during spore formation in bacillus subtilisIn: Cell Vol. 155 (2013) Nr. 3, pp. 647 - 658Online Full Text: dx.doi.org/
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Chemical Biology Approaches Reveal Conserved Features of a C-Terminal Processing PDZ ProteaseIn: ChemBioChem Vol. 13 (2012) Nr. 3, pp. 402 - 408Online Full Text: dx.doi.org/
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Detrimental role for human high temperature requirement serine protease A1 (HTRA1) in the pathogenesis of intervertebral disc (IVD) degenerationIn: The Journal of Biological Chemistry (JBC) Vol. 287 (2012) Nr. 25, pp. 21335 - 21345Online Full Text: dx.doi.org/
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Development of a Solid-Phase Approach to the Natural Product Class of Ahp-Containing CyclodepsipeptidesIn: European Journal of Organic Chemistry (2012) Nr. 8, pp. 1616 - 1625Online Full Text: dx.doi.org/
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E. coli LoiP (YggG), a metalloprotease hydrolyzing Phe–Phe bondsIn: Molecular BioSystems Vol. 8 (2012) Nr. 6, pp. 1775 - 1782Online Full Text: dx.doi.org/ Online Full Text
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Genetic analysis of 15 protein folding factors and proteases of the Escherichia coli cell envelopeIn: Journal of Bacteriology Vol. 194 (2012) Nr. 12, pp. 3225 - 3233Online Full Text: dx.doi.org/
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Human high temperature requirement serine protease A1 (HTRA1) degrades tau protein aggregatesIn: The Journal of Biological Chemistry (JBC) Vol. 287 (2012) Nr. 25, pp. 20931 - 20941Online Full Text: dx.doi.org/
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Human serine protease HTRA1 positively regulates osteogenesis of human bone marrow-derived mesenchymal stem cells and mineralization of differentiating bone-forming cells through the modulation of extracellular matrix proteinIn: Stem Cells Vol. 30 (2012) Nr. 10, pp. 2271 - 2282Online Full Text: dx.doi.org/ (Open Access)
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MiR-30e and miR-181d control Radial Glia cell proliferation via HtrA1 modulationIn: Cell Death and Disease Vol. 3 (2012) Nr. 8, e360Online Full Text: dx.doi.org/ (Open Access)
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Newly folded substrates inside the molecular cage of the HtrA chaperone DegQIn: Nature Structural & Molecular Biology Vol. 19 (2012) Nr. 2, pp. 152 - 157Online Full Text: dx.doi.org/
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HTRA proteases : regulated proteolysis in protein quality controlIn: Nature Reviews Molecular Cell Biology Vol. 12 (2011) Nr. 3, pp. 152 - 162Online Full Text: dx.doi.org/
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Lysine-specific molecular tweezers are broad-spectrum inhibitors of assembly and toxicity of amyloid proteinsIn: Journal of the American Chemical Society: JACS Vol. 133 (2011) Nr. 42, pp. 16958 - 16969Online Full Text: dx.doi.org/
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Molecular adaptation of the DegQ protease to exert protein quality control in the bacterial cell envelopeIn: The Journal of Biological Chemistry (JBC) Vol. 286 (2011) Nr. 35, pp. 30680 - 30690Online Full Text: dx.doi.org/
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Peptide Functionalized Polydiacetylene Liposomes Act as a Fluorescent Turn-On Sensor for Bacterial LipopolysaccharideIn: Journal of the American Chemical Society: JACS Vol. 133 (2011) Nr. 25, pp. 9720 - 9723Online Full Text: dx.doi.org/
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Protein quality control in the bacterial periplasmIn: Annual Review of Microbiology Vol. 65 (2011) pp. 149 - 168Online Full Text: dx.doi.org/
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Structural adaptation of the plant protease Deg1 to repair photosystem II during light exposureIn: Nature Structural & Molecular Biology Vol. 18 (2011) Nr. 6, pp. 728 - 731Online Full Text: dx.doi.org/
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Substrate induced remodeling of the active site regulates human HtrA1 activityIn: Nature Structural & Molecular Biology Vol. 18 (2011) pp. 386 - 388Online Full Text: dx.doi.org/
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Conversion of a regulatory into a degradative proteaseIn: Journal of Molecular Biology (JMB) Vol. 397 (2010) Nr. 4, pp. 957 - 966Online Full Text: dx.doi.org/
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Determinants of structural and functional plasticity of a widely conserved protease chaperone complexIn: Nature Structural & Molecular Biology Vol. 17 (2010) Nr. 7, pp. 837 - 843Online Full Text: dx.doi.org/
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Molecular transformers in the cell: lessons learned from the DegP protease-chaperoneIn: Current Opinion in Structural Biology Vol. 20 (2010) Nr. 2, pp. 253 - 258Online Full Text: dx.doi.org/
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Solid phase total synthesis of the 3-amino-6-hydroxy-2-piperidone (Ahp) cyclodepsipeptide and protease inhibitor Symplocamide AIn: Chemical Communications: ChemComm (2010) Nr. 46, pp. 8857 - 8859Online Full Text: dx.doi.org/
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The serine protease HtrA1 specifically interacts and degrades the tuberous sclerosis complex 2 proteinIn: Molecular Cancer Research Vol. 8 (2010) Nr. 9, pp. 1248 - 1260Online Full Text: dx.doi.org/
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Peptidic small molecule activators of the stress sensor DegSIn: Molecular BioSystems Vol. 5 (2009) Nr. 9, pp. 980 - 985Online Full Text: dx.doi.org/
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Selectivity profiling of DegP substrates and inhibitorsIn: Bioorganic and Medicinal Chemistry Vol. 17 (2009) Nr. 7, pp. 2920 - 2924Online Full Text: dx.doi.org/
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Structure, function and regulation of the conserved serine proteases DegP and DegS of Escherichia coliIn: Research in Microbiology Vol. 160 (2009) Nr. 9, pp. 660 - 666Online Full Text: dx.doi.org/
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Allosteric activation of HtrA protease DegP by stress signals during bacterial protein quality controlIn: Angewandte Chemie International Edition Vol. 47 (2008) Nr. 7, pp. 1332 - 1334Online Full Text: dx.doi.org/
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Allosteric regulation of proteasesIn: ChemBioChem Vol. 9 (2008) Nr. 18, pp. 2920 - 2928Online Full Text: dx.doi.org/ Online Full Text
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HtrA1-dependent proteolysis of TGF-β controls both neuronal maturation and developmental survivalIn: Cell Death and Differentiation Vol. 15 (2008) Nr. 9, pp. 1408 - 1416Online Full Text: dx.doi.org/ Online Full Text
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Interplay of PDZ and protease domain of DegP ensures efficient elimination of misfolded proteinsIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 22 (2008) pp. 7702 - 7707
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Structural basis for the regulated protease and chaperone function of DegP.In: Nature (2008) Nr. 453, pp. 885 - 890
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The serine protease HtrA1 is a novel prognostic factor for human mesotheliomaIn: Pharmacogenomics Vol. 9 (2008) Nr. 8, pp. 1069 - 1077
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Determinants of regulated proteolysis in signal transductionIn: Genes and Development Vol. 21 (2007) Nr. 1, pp. 6 - 10Online Full Text: dx.doi.org/
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Identification of Protein Disulfide Isomerase as a Cardiomyocyte Survival Factor in Ischemic CardiomyopathyIn: Journal of the American College of Cardiology (JACC) Vol. 50 (2007) Nr. 11, pp. 1029 - 1037Online Full Text: dx.doi.org/ (Open Access)
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Regulation of the σE stress response by DegS: How the PDZ domain keeps the protease inactive in the resting state and allows integration of different OMP-derived stress signals upon folding stressIn: Genes and Development Vol. 21 (2007) Nr. 20, pp. 2659 - 2670Online Full Text: dx.doi.org/
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Target directed proteolysis in vivo.In: Methods in Enzymology Vol. 421 (2007) pp. 68 - 83
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Functional characterization of a soluble gp130 isoform and its therapeutic capacity in an experimental model of inflammatory arthritisIn: Arthritis & Rheumatism Vol. 54 (2006) Nr. 5, pp. 1662 - 1672Online Full Text: dx.doi.org/
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Serine protease HtrA1 modulates chemotherapy-induced cytotoxicityIn: The Journal of Clinical Investigation (JCI) Vol. 116 (2006) Nr. 7, pp. 1994 - 2004Online Full Text: dx.doi.org/
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The role of human HtrA1 in arthritic disease.In: The Journal of Biological Chemistry (JBC) Vol. 281 (2006) Nr. 10, pp. 6124 - 6129
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Identification and structural characterisation of carboxy-terminal polypeptides and antibody epitopes of Alzheimer's amyloid precursor protein using high-resolution mass spectrometryIn: European Journal of Mass Spectrometry Vol. 11 (2005) Nr. 5, pp. 547 - 555
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Implications of human HtrA1 in amyloid precursor protein processing.In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 102 (2005) Nr. 17, pp. 6021 - 6026
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Implications of the serine protease HtrA1 in amyloid precursor protein processingIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 102 (2005) Nr. 17, pp. 6021 - 6026
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Target-directed proteolysis at the ribosome.In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 102 (2005) pp. 4246 - 4251
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Characterization of presenilin-amyloid precursor interaction using bacterial expression and two-hybrid systems for human membrane proteinsIn: Molecular Membrane Biology Vol. 21 (2004) Nr. 6, pp. 373 - 383Online Full Text: dx.doi.org/
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Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a proteaseIn: Cell Vol. 117 (2004) Nr. 4, pp. 483 - 494
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Proteolysis as a regulatory mechanismIn: Annual Review of Genetics Vol. 38 (2004) pp. 709 - 724Online Full Text: dx.doi.org/
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Context-dependent effects of charged residues in transmembrane segments of MalF-PhoA fusionsIn: Research in Microbiology Vol. 154 (2003) Nr. 9, pp. 654 - 657
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SecA-dependent quality control of intracellular protein localizationIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 100 (2003) Nr. 23, pp. 13231 - 13234
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Crystal structure of DegP (HtrA) reveals a new protease-chaperone machineIn: Nature Vol. 416 (2002) Nr. 6879, pp. 455 - 459
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The HtrA family of proteases : Implications for protein composition and cell fateIn: Molecular Cell Vol. 10 (2002) Nr. 3, pp. 443 - 455Online Full Text: dx.doi.org/
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A Novel Method to Determine the Topology of Peroxisomal Membrane Proteins in Vivo Using the Tobacco Etch Virus ProteaseIn: The Journal of Biological Chemistry (JBC) Vol. 276 (2001) Nr. 39, pp. 36501 - 36507
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Characterization of transmembrane segments 3, 4, and 5 of Ma1F by mutational analysisIn: Journal of Bacteriology Vol. 183 (2001) Nr. 1, pp. 375 - 381
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Evidence for coupling of membrane targeting and function of the signal recognition particle (SRP) receptor Fts YIn: EMBO Reports Vol. 2 (2001) Nr. 11, pp. 1040 - 1046
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Determinants of translocation and folding of TreF, a trehalase of Escherichia coliIn: The Journal of Biological Chemistry (JBC) Vol. 275 (2000) Nr. 31, pp. 23439 - 23445
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Synthesis of acyclic 6,7-dihaloquinolone nucleoside analogues as potential antibacterial and antiviral agents.In: Bioorganic & medicinal chemistry : a Tetrahedron publication for the rapid dissemination of full original research papers and critical reviews on biomolecular chemistry, medicinal chemistry and related disciplines Vol. 8 (2000) Nr. 6, pp. 1407 - 1413
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A temperature-dependent switch from chaperone to protease in a widely conserved heat shock proteinIn: Cell Vol. 97 (1999) Nr. 3, pp. 339 - 347
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Membrane topology of CadA homologous P-type ATPase of Helicobacter pylori as determined by expression of phoA fusions in Escherichia coli and the positive inside ruleIn: Research in Microbiology Vol. 150 (1999) Nr. 8, pp. 507 - 520
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Membrane topology of the xenobiotic-exporting subunit, MexB, of the MexA,B-OprM extrusion pump in Pseudomonas aeruginosaIn: The Journal of Biological Chemistry (JBC) Vol. 274 (1999) Nr. 15, pp. 10517 - 10522
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Eine hochspezifische Protease zur Struktur-und Funktionsanalyse von Proteinen in vivo und in vitro.In: Biospektrum: das Magazin für Biowissenschaften Vol. 3 (1998) pp. 53 - 56
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Polypeptide binding of Escherichia coil FtsH (HflB)In: Molecular Microbiology Vol. 28 (1998) Nr. 4, pp. 803 - 812
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Quinolone nucleosides: 6,7-dihalo-N-β- and α-glycosyl-1,4-dihydro-4- oxo-quinoline-3-carboxylic acids and derivatives. Synthesis, antimicrobial and antiviral activityIn: Nucleosides and Nucleotides Vol. 17 (1998) Nr. 12, pp. 2255 - 2266
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The ABC maltose transporterIn: Molecular Microbiology Vol. 29 (1998) Nr. 3, pp. 685 - 694
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The protein translocation apparatus contributes to determining the topology of an integral membrane protein in Escherichia coliIn: The Journal of Biological Chemistry (JBC) Vol. 273 (1998) Nr. 14, pp. 8419 - 8424
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Biochemical characterization and mass spectrometric disulfide bond mapping of periplasmic α-amylase mals of Escherichia coliIn: The Journal of Biological Chemistry (JBC) Vol. 272 (1997) Nr. 35, pp. 22125 - 22133
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Biogenese, Struktur und Funktion integraler Membranproteine: die Membrankomponenten des ABC-Maltosetransporters von Escherichia coli.In: Biospektrum: das Magazin für Biowissenschaften Vol. 2 (1997) pp. 46 - 47
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TnTIN and TnTAP: Mini-transposons for site-specific proteolysis in vivoIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 94 (1997) Nr. 24, pp. 13111 - 13115
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Characterization of a cytoplasmic trehalase of Escherichia coliIn: Journal of bacteriology : JB Vol. 178 (1996) Nr. 21, pp. 6250 - 6257
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Characterization of transmembrane domains 6, 7, and 8 of MalF by mutational analysisIn: Journal of bacteriology : JB Vol. 178 (1996) Nr. 8, pp. 2255 - 2262
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Site-specific proteolysis of the Escherichia coli SecA protein in vivoIn: Journal of bacteriology : JB Vol. 178 (1996) Nr. 10, pp. 2986 - 2988
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Targeting of signal sequenceless proteins for export in Escherichia coli with altered protein translocaseIn: The EMBO Journal Vol. 15 (1996) Nr. 19, pp. 5209 - 5217
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Synthetic competition between cytoplasmic folding and translocation of a soluble membrane protein domainIn: Research in Microbiology Vol. 146 (1995) Nr. 2, pp. 121 - 128
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Requirements for translocation of periplasmic domains in polytopic membrane proteinsIn: Journal of bacteriology : JB Vol. 176 (1994) Nr. 15, pp. 4565 - 4571
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Sec-independent translocation of a 100-residue periplasmic N-terminal tail in the E.coli inner membrane protein proWIn: The EMBO Journal Vol. 13 (1994) Nr. 19, pp. 4653 - 4661
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The Saccharomyces cerevisiae gene PPH3 encodes a protein phosphatase with properties different from PPX, PP1 and PP2AIn: Yeast Vol. 10 (1994) Nr. 5, pp. 567 - 578Online Full Text: dx.doi.org/
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Decoding signals for membrane protein assembly using alkaline phosphatase fusionsIn: The EMBO Journal Vol. 10 (1991) Nr. 10, pp. 2773 - 2782
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Proper insertion of a complex membrane protein in the absence of its amino-terminal export signalIn: The Journal of Biological Chemistry (JBC) Vol. 266 (1991) Nr. 25, pp. 16530 - 16533
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Genetic analysis of membrane protein topology by a sandwich gene fusion approach.In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 87 (1990) Nr. 19, pp. 7574 - 7578
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MalI, a novel protein involved in regulation of the maltose system of Escherichia coli, is highly homologous to the repressor proteins GalR, CytR, and LacI.In: Journal of bacteriology : JB Vol. 171 (1989) Nr. 9, pp. 4888 - 4899
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Convenient transfer of lacZ-gene fusions to phage M13 by in vivo recombination and their use for nucleotide sequencingIn: Gene : an international journal focusing on gene cloning and gene structure and function Vol. 71 (1988) Nr. 1, pp. 187 - 191
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Divergent transcription of the sn-glycerol-3-phosphate active transport (glpT) and anaerobic sn-glycerol-3-phosphate dehydrogenase (glpA glpC glpB) genes of Escherichia coli K-12In: Journal of Bacteriology Vol. 169 (1987) Nr. 2, pp. 526 - 532Online Full Text: dx.doi.org/
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Identification of endogenous inducers of the mal regulon in Escherichia coli.In: Journal of bacteriology : JB Vol. 169 (1987) Nr. 8, pp. 3539 - 3545
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Osmoregulation of the maltose regulon in Escherichia coli.In: Journal of bacteriology : JB Vol. 166 (1986) Nr. 3, pp. 884 - 891
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Periplasmic glycerophosphodiester phosphodiesterase of Escherichia coli, a new enzyme of the glp regulonIn: The Journal of Biological Chemistry (JBC) Vol. 258 (1983) Nr. 9, pp. 5428 - 5432
Journal articles
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