Publications

    Journal articles

  • Hommel, Katrin; Kauth, Alisa-Maite A.; Kirupakaran, Abbna; Theisen, Sebastian; Hayduk, Matthias; Niemeyer, Felix C.; Beuck, Christine; Zadmard, Reza; Bayer, Peter; Jan Ravoo, Bart; Voskuhl, Jens; Schrader, Thomas; Knauer, Shirley K.
    Functional Linkers Support Targeting of Multivalent Tweezers to Taspase1
    In: Chemistry - A European Journal Vol. 30 (2024) Nr. 56, e202401542
    Online Full Text: dx.doi.org/ (Open Access)
  • Balszuweit, Jan; Stahl, Paul; Cappellari, Victoria; Lorberg, Rick Y.; Wölper, Christoph; Niemeyer, Felix; Koch, Johannes; Prymak, Oleg; Knauer, Shirley; Strassert, Cristian A.; Voskuhl, Jens
    Merging of a Supramolecular Ligand with a Switchable Luminophore : Light-Responsiveness, Photophysics and Bioimaging
    In: Chemistry - A European Journal (2024) e202402578 in press
    Online Full Text: dx.doi.org/ (Open Access)
  • Zwiehoff, Sandra; Hensel, Astrid; Rishmawi, Ramin; Shakibaei, Parisa; Behrends, Carina; Hommel, Katrin; Bäumer, Christian; Knauer, Shirley Karin; Timmermann, Beate; Rehbock, Christoph; Barcikowski, Stephan
    Synergetic Enhancing Effects between Platinum Nanosensitizers and Clinically Approved Stabilizing Ligands in Proton Therapy, Causing High-Yield Double-Strand Breaks of Plasmid DNA at Relevant Dose
    In: Advanced NanoBiomed Research (2024) in press
    Online Full Text: dx.doi.org/ (Open Access)
  • Aldemir, Nazli; Vallet, Cecilia; Knauer, Shirley; Schmuck, Carsten; Hirschhäuser, Christoph
    A Fluorophore-Labeled Lysine Dendrimer with an Oxo-Anion-Binding Motif for Tracking Gene Transfection
    In: ChemBioChem Vol. 24 (2023) Nr. 15, e202300296
    Online Full Text: dx.doi.org/ (Open Access)
  • Dubbert, Justin; Höing, Alexander; Graupner, Nadine; Rajter, Lubomir; Dunthorn, Micah; Knauer, Shirley; Galstyan, Anzhela; Rizzo, Fabio; Voskuhl, Jens
    Cationic Solution and Solid‐state Emitters : Robust Imaging Agents for Cells, Bacteria and Protists
    In: Chemistry - A European Journal Vol. 29 (2023) Nr. 38, e202300334
    Online Full Text: dx.doi.org/ (Open Access)
  • Huber, Alexander; Koch, Johannes; Rudolph, Kevin; Höing, Alexander; Rizzo, Fabio; Knauer, Shirley; Voskuhl, Jens
    Deoxyestrone-based lipofection agents with solution- and solid-state emission properties
    In: Organic and Biomolecular Chemistry Vol. 21 (2023) pp. 5762 - 5767
    Online Full Text: dx.doi.org/ (Open Access)
  • Koll, Laura; Gül, Désirée; Elnouaem, Manal I.; Raslan, Hanaa; Ramadan, Omneya R.; Knauer, Shirley; Strieth, Sebastian; Hagemann, Jan; Stauber, Roland H.; Khamis, Aya
    Exploiting Vitamin D Receptor and Its Ligands to Target Squamous Cell Carcinomas of the Head and Neck
    In: International Journal of Molecular Sciences (IJMS) Vol. 24 (2023) Nr. 5, 4675
    Online Full Text: dx.doi.org/ (Open Access)
  • Jana, Poulami; Samanta, Krishnananda; Ehlers, Martin; Zellermann, Elio; Bäcker, Sandra; Stauber, Roland H.; Schmuck, Carsten; Knauer, Shirley
    Impact of Peptide Sequences on Their Structure and Function : Mimicking of Virus-Like Nanoparticles for Nucleic Acid Delivery
    In: ChemBioChem Vol. 24 (2023) Nr. 1, e202200519
    Online Full Text: dx.doi.org/ (Open Access)
  • Seiler, Theresa; Lennartz, Annika; Klein, Kai; Hommel, Katrin; Figueroa Bietti, Antonio; Hadrovic, Inesa; Kollenda, Sebastian; Sager, Jonas; Beuck, Christine; Chlosta, Emilia; Bayer, Peter; Juul-Madsen, Kristian; Vorup-Jensen, Thomas; Schrader, Thomas; Epple, Matthias; Knauer, Shirley; Hartmann, Laura
    Potentiating Tweezer Affinity to a Protein Interface with Sequence-Defined Macromolecules on Nanoparticles
    In: Biomacromolecules Vol. 24 (2023) Nr. 8, pp. 3666 - 3679
    Online Full Text: dx.doi.org/
  • Oelschläger, Lisa; Stahl, Paul; Kaschani, Farnusch; Stauber, Roland H.; Knauer, Shirley K.; Hensel, Astrid
    Taspase1 facilitates Topoisomerase IIβ-mediated DNA double-strand breaks driving estrogen-induced transcription
    In: Cells Vol. 2023 (2023) Nr. 12, 363
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Breder-Bonk, Christina; Docter, Dominic; Barz, Matthias; Strieth, Sebastian; Knauer, Shirley; Gül, Désirée; Stauber, Roland H.
    The Apoptosis Inhibitor Protein Survivin Is a Critical Cytoprotective Resistor against Silica-Based Nanotoxicity
    In: Nanomaterials Vol. 13 (2023) Nr. 18, 2546
    Online Full Text: dx.doi.org/ (Open Access)
  • Stahl, Paul; Kollenda, Sebastian; Sager, Jonas; Schmidt, Laura; Schroer, Martin; Stauber, Roland H.; Epple, Matthias; Knauer, Shirley
    Tuning Nanobodies’ Bioactivity : Coupling to Ultrasmall Gold Nanoparticles Allows the Intracellular Interference with Survivin
    In: Small Vol. 19 (2023) Nr. 33, 2300871 10.1002/smll.202300871
    Online Full Text: dx.doi.org/ (Open Access)
  • Höing, Alexander; Zimmermann, Alexander; Moews, Lisa; Killa, Matthias; Heimann, Marius; Hensel, Astrid; Voskuhl, Jens; Knauer, Shirley
    A Bivalent Supramolecular GCP Ligand Enables Blocking of the Taspase1/Importin α Interaction
    In: ChemMedChem Vol. 17 (2022) Nr. 1, e202100640
    Online Full Text: dx.doi.org/ (Open Access)
  • Dirksmeyer, Thies; Stahl, Paul; Vallet, Cecilia; Knauer, Shirley; Giese, Michael R. A.; Schmuck, Carsten; Hirschhäuser, Christoph
    Advances towards Cell‐Specific Gene Transfection : A Small‐Molecule Approach Allows Order‐of‐Magnitude Selectivity
    In: Chemistry - A European Journal Vol. 28 (2022) Nr. 43, e202202024
    Online Full Text: dx.doi.org/; Online Full Text: dx.doi.org/ (Open Access)
  • Rafieiolhosseini, Neda; Killa, Matthias; Neumann, Thorben; Tötsch, Niklas; Grad, Jean-Noël; Höing, Alexander; Dirksmeyer, Thies; Niemeyer, Jochen; Ottmann, Christian; Knauer, Shirley K; Giese, Michael; Voskuhl, Jens; Hoffmann, Daniel
    Computational model predicts protein binding sites of a luminescent ligand equipped with guanidiniocarbonyl-pyrrole groups
    In: Beilstein Journal of Organic Chemistry Vol. 18 (2022) pp. 1322 - 1331
    Online Full Text: dx.doi.org/ (Open Access)
  • Höing, Alexander; Struth, Robin; Beuck, Christine; Rafieiolhosseini, Neda; Hoffmann, Daniel; Stauber, Roland H.; Bayer, Peter; Niemeyer, Jochen; Knauer, Shirley
    Dual activity inhibition of threonine aspartase 1 by a single bisphosphate ligand
    In: RSC Advances Vol. 12 (2022) Nr. 53, pp. 34176 - 34184
    Online Full Text: dx.doi.org/ (Open Access)
  • Rick, Tim; Kreiling, Vanessa; Höing, Alexander; Fiedler, Svenja; Glatter, Timo; Steinchen, Wieland; Hochberg, Georg; Bähre, Heike; Seifert, Roland; Bange, Gert; Knauer, Shirley K.; Graumann, Peter L.; Thormann, Kai M.; Roland, Seifert
    GGDEF domain as spatial on-switch for a phosphodiesterase by interaction with landmark protein HubP
    In: npj Biofilms and Microbiomes Vol. 8 (2022) Nr. 1, 35
    Online Full Text: dx.doi.org/ (Open Access)
  • Gül, Désirée; Schweitzer, Andrea; Khamis, Aya; Knauer, Shirley; Ding, Guo-Bin; Freudelsperger, Laura; Karampinis, Ioannis; Strieth, Sebastian; Hagemann, Jan; Stauber, Roland H.
    Impact of Secretion-Active Osteoblast-Specific Factor 2 in Promoting Progression and Metastasis of Head and Neck Cancer
    In: Cancers Vol. 14 (2022) Nr. 9, 2337
    Online Full Text: dx.doi.org/ (Open Access)
  • Höing, Alexander; Kirupakaran, Abbna; Beuck, Christine; Pörschke, Marius; Niemeyer, Felix; Seiler, Theresa; Hartmann, Laura; Bayer, Peter; Schrader, Thomas; Knauer, Shirley
    Recognition of a Flexible Protein Loop in Taspase 1 by Multivalent Supramolecular Tweezers
    In: Biomacromolecules Vol. 23 (2022) Nr. 11, pp. 4504 - 4518
    Online Full Text: dx.doi.org/
  • Aschmann, Dennis; Vallet, Cecilia; Tripathi, Sunil K.; Ruiz-Blanco, Yasser B.; Brabender, Max; Schmuck, Carsten; Sánchez-García, Elsa; Knauer, Shirley; Giese, Michael
    Selective Disruption of Survivin's Protein-Protein Interactions : A Supramolecular Approach Based on Guanidiniocarbonylpyrrole
    In: ChemBioChem Vol. 23 (2022) Nr. 5, e202100618
    Online Full Text: dx.doi.org/ (Open Access)
  • Hensel, Astrid; Stahl, Paul; Moews, Lisa; König, Lena; Patwardhan, Rutuja; Höing, Alexander; Schulze, Nina; Nalbant, Perihan; Stauber, Roland H.; Knauer, Shirley
    The Taspase1/Myosin1f-axis regulates filopodia dynamics
    In: iScience Vol. 25 (2022) Nr. 6, 104355
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Khamis, Aya; Gül, Désirée; Wandrey, Madita; Lu, Qiang; Knauer, Shirley; Reinhardt, Christoph; Strieth, Sebastian; Hagemann, Jan; Stauber, Roland H.
    The Vitamin D Receptor–BIM Axis Overcomes Cisplatin Resistance in Head and Neck Cancer
    In: Cancers Vol. 14 (2022) Nr. 20, 5131
    Online Full Text: dx.doi.org/ (Open Access)
  • Marks, David; Heinen, Natalie; Bachmann, Lisa; Meermeyer, Sophia; Werner, Michelle; Gallego, Lucia; Hemmerich, Peter; Bader, Verian; Winklhofer, Konstanze F.; Schröder, Elisabeth; Knauer, Shirley; Müller, Thorsten
    Amyloid precursor protein elevates fusion of promyelocytic leukemia nuclear bodies in human hippocampal areas with high plaque load
    In: Acta Neuropathologica Communications Vol. 9 (2021) Nr. 1, pp. 66
    Online Full Text: dx.doi.org/ (Open Access)
  • Zimmermann, Alexander; Jaber, Qais Z.; Koch, Johannes; Riebe, Steffen; Vallet, Cecilia; Loza, Kateryna; Hayduk, Matthias; Steinbuch, Kfir B.; Knauer, Shirley; Fridman, Micha; Voskuhl, Jens
    Luminescent Amphiphilic Aminoglycoside Probes to Study Transfection
    In: ChemBioChem Vol. 22 (2021) Nr. 9, pp. 1563 - 1567
    Online Full Text: dx.doi.org/ (Open Access)
  • van der Meer, Selina Beatrice; Hadrovic, Inesa; Meiners, Annika; Loza, Kateryna; Heggen, Marc; Knauer, Shirley; Bayer, Peter; Schrader, Thomas; Beuck, Christine; Epple, Matthias
    New tools to probe the protein surface : Ultrasmall gold nanoparticles carry amino acid binders
    In: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry Vol. 125 (2021) Nr. 1, pp. 115 - 127
    Online Full Text: dx.doi.org/ (Open Access)
  • Pasch, Peter; Höing, Alexander; Ueclue, Serap; Killa, Matthias; Voskuhl, Jens; Knauer, Shirley; Hartmann, Laura
    PEGylated sequence-controlled macromolecules using supramolecular binding to target the Taspase1/Importin α interaction
    In: Chemical Communications: ChemComm Vol. 57 (2021) Nr. 25, pp. 3091 - 3094
    Online Full Text: dx.doi.org/ (Open Access)
  • Meiners, Annika; Bäcker, Sandra; Hadrovic, Inesa; Heid, Christian; Beuck, Christine; Ruiz-Blanco, Yasser B.; Mieres-Perez, Joel; Pörschke, Marius; Grad, Jean-Noël; Vallet, Cecilia; Hoffmann, Daniel; Bayer, Peter; Sánchez-García, Elsa; Schrader, Thomas; Knauer, Shirley
    Specific inhibition of the Survivin–CRM1 interaction by peptide-modified molecular tweezers
    In: Nature Communications Vol. 12 (2021) Nr. 1, pp. 1505
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Hussain, Timon; Gellrich, Donata; Siemer, Svenja; Reichel, Christoph A.; Eckrich, Jonas; Dietrich, Dimo; Knauer, Shirley; Stauber, Roland H.; Strieth, Sebastian
    TNF-α-Inhibition Improves the Biocompatibility of Porous Polyethylene Implants In Vivo
    In: Tissue Engineering and Regenerative Medicine Vol. 18 (2021) Nr. 2, pp. 297 - 303
    Online Full Text: dx.doi.org/ (Open Access)
  • Sowa, Andrea; Höing, Alexander; Dobrindt, Ulrich; Knauer, Shirley; Galstyan, Anzhela; Voskuhl, Jens
    Umbelliferone Decorated Water-soluble Zinc(II) Phthalocyanines : In Vitro Phototoxic Antimicrobial Anti-cancer Agents
    In: Chemistry - A European Journal Vol. 27 (2021) Nr. 59, pp. 14672 - 14680
    Online Full Text: dx.doi.org/ (Open Access)
  • Gigante, Alba; Sijbesma, Eline; Sánchez-Murcia, Pedro A.; Hu, Xiaoyu; Bier, David; Bäcker, Sandra; Knauer, Shirley; Gago, Federico; Ottmann, Christian; Schmuck, Carsten
    A Supramolecular Stabilizer of the 14-3-3ζ/ERα Protein-Protein Interaction with a Synergistic Mode of Action
    In: Angewandte Chemie International Edition Vol. 132 (2020) Nr. 13, pp. 5322 - 5325
    Online Full Text: dx.doi.org/ (Open Access)
  • Westmeier, Dana; Siemer, Svenja; Vallet, Cecilia; Steinmann, Jörg; Docter, Dominic; Buer, Jan; Knauer, Shirley; Stauber, Roland H.
    Boosting nanotoxicity to combat multidrug-resistant bacteria in pathophysiological environments
    In: Nanoscale Advances Vol. 2 (2020) Nr. 11, pp. 5428 - 5440
    Online Full Text: dx.doi.org/ (Open Access)
  • Maity, Suman Kumar; Stahl, Paul; Hensel, Astrid; Knauer, Shirley; Hirschhäuser, Christoph; Schmuck, Carsten
    Cancer-Cell-Specific Drug Delivery by a Tumor-Homing CPP-Gossypol Conjugate Employing a Tracelessly Cleavable Linker
    In: Chemistry - A European Journal Vol. 26 (2020) Nr. 14, pp. 3010 - 3015
    Online Full Text: dx.doi.org/ (Open Access)
  • Westmeier, Dana; Posselt, Gernot; Hahlbrock, Angelina; Bartfeld, Sina; Vallet, Cecilia; Abfalter, Carmen; Docter, Dominic; Knauer, Shirley; Wessler, Silja; Stauber, Roland H.
    Erratum : Nanoparticle binding attenuates the pathobiology of gastric cancer-associated: Helicobacter pylori
    In: Nanoscale Vol. 12 (2020) Nr. 3, pp. 2154 - 2155
    Online Full Text: dx.doi.org/ (Open Access)
  • Vallet, Cecilia; Aschmann, Dennis; Beuck, Christine; Killa, Matthias; Meiners, Annika; Mertel, Marcel; Ehlers, Martin; Bayer, Peter; Schmuck, Carsten; Giese, Michael R. A.; Knauer, Shirley
    Functional Disruption of the Cancer-Relevant Interaction between Survivin and Histone H3 with a Guanidiniocarbonyl Pyrrole Ligand
    In: Angewandte Chemie International Edition Vol. 59 (2020) Nr. 14, pp. 5567 - 5571
    Online Full Text: dx.doi.org/ (Open Access)
  • Riebe, Steffen; Zimmermann, Alexander; Koch, Johannes; Vallet, Cecilia; Knauer, Shirley; Sowa, Andrea; Wölper, Christoph; Voskuhl, Jens
    Lipofection with estrone-based luminophores featuring aggregation-induced emission properties
    In: RSC Advances Vol. 10 (2020) Nr. 33, pp. 19643 - 19647
    Online Full Text: dx.doi.org/ (Open Access)
  • Stauber, Roland H.; Westmeier, Dana; Wandrey, Madita; Becker, Sven; Docter, Dominic; Ding, Guo-Bin; Thines, Eckhard; Knauer, Shirley; Siemer, Svenja
    Mechanisms of nanotoxicity – biomolecule coronas protect pathological fungi against nanoparticle-based eradication
    In: Nanotoxicology Vol. 14 (2020) Nr. 9, pp. 1157 - 1174
    Online Full Text: dx.doi.org/
  • Saha, Subrata; Klein-Hitpaß, Marcel; Vallet, Cecilia; Knauer, Shirley; Schmuck, Carsten; Voskuhl, Jens; Giese, Michael R. A.
    Smart Glycopolymeric Nanoparticles for Multivalent Lectin Binding and Stimuli-Controlled Guest Release
    In: Biomacromolecules Vol. 21 (2020) Nr. 6, pp. 2356 - 2364
    Online Full Text: dx.doi.org/
  • Dubbert, Justin; Höing, Alexander; Riek, Nathalie; Knauer, Shirley; Voskuhl, Jens
    Supramolecular subphthalocyanine complexes-cellular uptake and phototoxicity
    In: Chemical Communications: ChemComm Vol. 56 (2020) Nr. 55, pp. 7653 - 7656
    Online Full Text: dx.doi.org/
  • van den Boom, Johannes; Hensel, Astrid; Trusch, Franziska; Matena, Anja; Siemer, Svenja; Guel, Désirée; Docter, Dominic; Höing, Alexander; Bayer, Peter; Stauber, Roland H.; Knauer, Shirley
    The other side of the corona : Nanoparticles inhibit the protease taspase1 in a size-dependent manner
    In: Nanoscale Vol. 12 (2020) Nr. 37, pp. 19093 - 19103
    Online Full Text: dx.doi.org/
  • Jiang, Hao; Hu, Xiao-Yu; Mosel, Stefanie; Knauer, Shirley; Hirschhäuser, Christoph; Schmuck, Carsten
    A Branched Tripeptide with an Anion-Binding Motif as a Novel Delivery Carrier for Efficient Gene Transfection
    In: ChemBioChem Vol. 20 (2019) Nr. 11, pp. 1410 - 1416
    Online Full Text: dx.doi.org/
  • Maity, Debabrata; Gigante, Alba; Sánchez-Murcia, Pedro A.; Sijbesma, Eline; Li, Mao; Bier, David; Mosel, Stefanie; Knauer, Shirley; Ottmann, Christian; Schmuck, Carsten
    Arginine mimetic appended peptide-based probes for fluorescence turn-on detection of 14-3-3 proteins
    In: Organic and Biomolecular Chemistry Vol. 17 (2019) Nr. 17, pp. 4359 - 4363
    Online Full Text: dx.doi.org/
  • Siemer, Svenja; Westmeier, Dana; Barz, Matthias; Eckrich, Jonas; Wünsch, Désirée; Seckert, Christof; Thyssen, Christian; Schilling, Oliver; Hasenberg, Mike; Pang, Chengfan; Docter, Dominic; Knauer, Shirley K.; Stauber, Roland H.; Strieth, Sebastian
    Biomolecule-corona formation confers resistance of bacteria to nanoparticle-induced killing : Implications for the design of improved nanoantibiotics
    In: Biomaterials Vol. 192 (2019) pp. 551 - 559
    Online Full Text: dx.doi.org/
  • Gribko, Alena; Künzel, Julian; Wünsch, Désirée; Lu, Qiang; Nagel, Sophie Madeleine; Knauer, Shirley; Stauber, Roland H.; Ding, Guo-Bin
    Is small smarter? Nanomaterial-based detection and elimination of circulating tumor cells : Current knowledge and perspectives
    In: International Journal of Nanomedicine Vol. 14 (2019) pp. 4187 - 4209
    Online Full Text: dx.doi.org/ (Open Access)
  • Gigante, Alba; Li, Mao; Junghänel, Sandra; Hirschhäuser, Christoph; Knauer, Shirley; Schmuck, Carsten
    Non-viral transfection vectors : Are hybrid materials the way forward?
    In: MedChemComm Vol. 10 (2019) Nr. 10, pp. 1692 - 1718
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Knauer, Shirley; Feis, Alessandro; Schlücker, Sebastian; Wissler, Jörg; Bäcker, Sandra
    Protein Dimerization Probed with Site-Specific Attached Single Nanoparticles
    In: Biophysical Journal Vol. 116 (2019) Nr. 3, Suppl. 1, pp. 284a
    Online Full Text: dx.doi.org/ (Open Access)
  • Siemer, Svenja; Westmeier, Dana; Vallet, Cecilia; Steinmann, Jörg; Buer, Jan; Stauber, Roland H.; Knauer, Shirley
    REMOVED: Breaking resistance to nanoantibiotics by overriding corona-dependent inhibition using a pH-switch
    In: Materials Today Vol. 26 (2019) pp. 19 - 29
    Online Full Text: dx.doi.org/ (Open Access)
  • Siemer, Svenja; Westmeier, Dana; Vallet, Cecilia; Becker, Sven; Voskuhl, Jens; Ding, Guo-Bin; Thines, Eckhard; Stauber, Roland H.; Knauer, Shirley
    Resistance to Nano-Based Antifungals Is Mediated by Biomolecule Coronas
    In: ACS Applied Materials & Interfaces Vol. 11 (2019) Nr. 1, pp. 104 - 114
    Online Full Text: dx.doi.org/
  • Li, Mao; Mosel, Stefanie; Knauer, Shirley; Schmuck, Carsten
    A dipeptide with enhanced anion binding affinity enables cell uptake and protein delivery
    In: Organic and Biomolecular Chemistry Vol. 16 (2018) Nr. 13, pp. 2312 - 2317
    Online Full Text: dx.doi.org/
  • Goesswein, Dorothee; Habtemichael, Negusse; Gerhold-Ay, Aslihan; Mazur, Johanna; Wünsch, Désirée; Knauer, Shirley; Künzel, Julian; Matthias, Christoph; Strieth, Sebastian; Stauber, Roland H
    Expressional analysis of disease-relevant signalling-pathways in primary tumours and metastasis of head and neck cancers.
    In: Scientific Reports Vol. 8 (2018) Nr. 1, pp. 7326
    Online Full Text: dx.doi.org/ (Open Access)
  • Hu, Xiao-Yu; Ehlers, Martin; Wang, Tingting; Zellermann, Elio; Mosel, Stefanie; Jiang, Hao; Ostwaldt, Jan-Erik; Knauer, Shirley; Wang, Leyong; Schmuck, Carsten
    Formation of Twisted β-Sheet Tapes from a Self-Complementary Peptide Based on Novel Pillararene-GCP Host–Guest Interaction with Gene Transfection Properties
    In: Chemistry - A European Journal Vol. 24 (2018) Nr. 39, pp. 9754 - 9759
    Online Full Text: dx.doi.org/
  • Hu, Xiao-Yu; Gao, Lei; Mosel, Stefanie; Ehlers, Martin; Zellermann, Elio; Jiang, Hao; Knauer, Shirley; Wang, Leyong; Schmuck, Carsten
    From Supramolecular Vesicles to Micelles : Controllable Construction of Tumor-Targeting Nanocarriers Based on Host–Guest Interaction between a Pillar[5]arene-Based Prodrug and a RGD-Sulfonate Guest
    In: Small Vol. 14 (2018) Nr. 52, pp. 1803952
    Online Full Text: dx.doi.org/
  • Müller, Jonathan W.; Idkowiak, Jan; Gesteira, Tarsis F.; Vallet, Cecilia; Hardman, Rebecca; van den Boom, Johannes; Dhir, Vivek; Knauer, Shirley; Rosta, Edina; Arlt, Wiebke
    Human DHEA sulfation requires direct interaction between PAPS synthase 2 and DHEA sulfotransferase SULT2A1
    In: The Journal of Biological Chemistry (JBC) Vol. 293 (2018) Nr. 25, pp. 9724 - 9735
    Online Full Text: dx.doi.org/ (Open Access)
  • Feuerecker, Benedikt; Stauber, Roland; Reichert, Maximilian; Schneeweis, Christian; Rad, Roland; Saur, Dieter; Hassan, Zonera; Schneider, Günter; Ceyhan, Güralp O; Knauer, Shirley; Wirth, Matthias; Schmid, Roland M; Dantes, Zahra; Arlt, Alexander; Krämer, Oliver H; Veltkamp, Christian; Weichert, Wilko
    MTOR inhibitor-based combination therapies for pancreatic cancer
    In: British Journal of Cancer (BJC) Vol. 118 (2018) pp. 366 - 377
    Online Full Text: dx.doi.org/ (Open Access)
  • Westmeier, Dana; Hahlbrock, Angelina; Reinhardt, Christoph; Fröhlich-Nowoisky, Janine; Wessler, Silja; Vallet, Cecilia; Pöschl, Ulrich; Knauer, Shirley; Stauber, Roland H.
    Nanomaterial-microbe cross-talk : physicochemical principles and (patho)biological consequences
    In: Chemical Society Reviews Vol. 47 (2018) Nr. 14, pp. 5312 - 5337
    Online Full Text: dx.doi.org/
  • Abfalter, Carmen; Docter, Dominic; Wessler, Silja; Vallet, Cecilia; Westmeier, Dana; Knauer, Shirley; Posselt, Gernot; Stauber, Roland H.; Hahlbrock, Angelina; Bartfeld, Sina
    Nanoparticle binding attenuates the pathobiology of gastric cancer-associated Helicobacter pylori
    In: Nanoscale Vol. 10 (2018) Nr. 3, pp. 1453 - 1463
    Online Full Text: dx.doi.org/
  • Westmeier, Dana; Solouk-Saran, Djamschid; Vallet, Cecilia; Siemer, Svenja; Docter, Dominic; Götz, Hermann; Männ, Linda; Hasenberg, Anja; Hahlbrock, Angelina; Erler, Kathrin; Reinhardt, Christoph; Schilling, Oliver; Becker, Sven; Gunzer, Matthias; Hasenberg, Mike; Knauer, Shirley; Stauber, Roland H.
    Nanoparticle decoration impacts airborne fungal pathobiology
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 115 (2018) Nr. 27, pp. 7087 - 7092
    Online Full Text: dx.doi.org/ (Open Access)
  • Voskuhl, Jens; Docter, Dominic; Vallet, Cecilia; Hahlbrock, Angelina; Stauber, Roland H.; Westmeier, Dana; McClements, David Julian; Wessler, Silja; Knauer, Shirley; Siemer, Svenja; Balszuweit, Jan
    Nanosized food additives impact beneficial and pathogenic bacteria in the human gut : a simulated gastrointestinal study
    In: npj Science of Food Vol. 2 (2018) pp. 22
    Online Full Text: dx.doi.org/ (Open Access)
  • Stelzer, Jacqueline; Vallet, Cecilia; Sowa, Andrea; Gonzalez-Abradelo, Dario; Riebe, Steffen; Daniliuc, Constantin G.; Ehlers, Martin; Strassert, Cristian. A.; Knauer, Shirley; Voskuhl, Jens
    On the influence of substitution patterns in thioether-based luminophores with aggregation-induced emission properties
    In: ChemistrySelect Vol. 3 (2018) Nr. 4, pp. 985 - 991
    Online Full Text: dx.doi.org/
  • Wissler, Jörg; Wehmeyer, Martin; Bäcker, Sandra; Knauer, Shirley; Schlücker, Sebastian
    Simultaneous Rayleigh/Mie and Raman/Fluorescence Characterization of Molecularly Functionalized Colloids by Correlative Single-Particle Real-Time Imaging in Suspension
    In: Analytical Chemistry Vol. 90 (2018) Nr. 1, pp. 723 - 728
    Online Full Text: dx.doi.org/
  • Stauber, Roland H.; Siemer, Svenja; Becker, Sven; Ding, Guo-Bin; Strieth, Sebastian; Knauer, Shirley
    Small Meets Smaller : Effects of Nanomaterials on Microbial Biology, Pathology, and Ecology
    In: ACS Nano Vol. 12 (2018) Nr. 7, pp. 6351 - 6359
    Online Full Text: dx.doi.org/
  • Rauch, Anke; Carlstedt, Annemarie; Emmerich, Claudia; Mustafa, Al-Hassan M.; Göder, Anja; Knauer, Shirley; Linnebacher, Michael; Heinzel, Thorsten; Krämer, Oliver H.
    Survivin antagonizes chemotherapy-induced cell death of colorectal cancer cells
    In: OncoTarget Vol. 9 (2018) Nr. 45, pp. 27835 - 27850
    Online Full Text: dx.doi.org/ (Open Access)
  • Schrenk, Christian; Fetz, Verena; Vallet, Cecilia; Heiselmayer, Christina; Schröder, Elisabeth; Hensel, Astrid; Hahlbrock, Angelina; Wünsch, Désirée; Goesswein, Dorothee; Bier, Carolin; Habtemichael, Negusse; Schneider, Günter; Stauber, Roland H.; Knauer, Shirley
    TFIIA transcriptional activity is controlled by a 'cleave-And-run' Exportin-1/Taspase 1-switch
    In: Journal of Molecular Cell Biology Vol. 10 (2018) Nr. 1, pp. 33 - 47
    Online Full Text: dx.doi.org/ (Open Access)
  • Junghänel, Sandra; Karczewski, Sarah; Bäcker, Sandra; Knauer, Shirley; Schmuck, Carsten
    A systematic structure–activity study of a new type of small peptidic transfection vector reveals the importance of a special oxo-anion-binding motif for gene delivery
    In: ChemBioChem Vol. 18 (2017) Nr. 22, pp. 2268 - 2279
    Online Full Text: dx.doi.org/
  • Riebe, Steffen; Vallet, Cecilia; van der Vight, Felix; Gonzalez-Abradelo, Dario; Wölper, Christoph; Strassert, Cristian A.; Jansen, Georg; Knauer, Shirley; Voskuhl, Jens
    Aromatic thioethers as novel luminophores with aggregation-induced fluorescence and phosphorescence
    In: Chemistry - A European Journal Vol. 23 (2017) Nr. 55, pp. 13660 - 13668
    Online Full Text: dx.doi.org/
  • Jana, Poulami; Samanta, Krishnananda; Bäcker, Sandra; Zellermann, Elio; Knauer, Shirley; Schmuck, Carsten
    Efficient Gene Transfection through Inhibition of β-Sheet (Amyloid Fiber) Formation of a Short Amphiphilic Peptide by Gold Nanoparticles
    In: Angewandte Chemie International Edition Vol. 56 (2017) Nr. 28, pp. 8083 - 8088
    Online Full Text: dx.doi.org/
  • Jiang, Hao; Hu, Xiao-Yu; Schlesiger, Stefanie; Li, Mao; Zellermann, Elio; Knauer, Shirley; Schmuck, Carsten
    Morphology-Dependent Cell Imaging by Using a Self-Assembled Diacetylene Peptide Amphiphile
    In: Angewandte Chemie International Edition Vol. 56 (2017) Nr. 46, pp. 14526 - 14530
    Online Full Text: dx.doi.org/
  • Wissler, Jörg; Bäcker, Sandra; Feis, Alessandro; Knauer, Shirley; Schlücker, Sebastian
    Site-Specific SERS Assay for Survivin Protein Dimer : From Ensemble Experiments to Correlative Single-Particle Imaging
    In: Small Vol. 13 (2017) Nr. 32, pp. 1700802
    Online Full Text: dx.doi.org/
  • Scheer, Alexandra; Knauer, Shirley; Verhaegh, Rabea
    Survivin expression pattern in the intestine of normoxic and ischemic rats
    In: BMC Gastroenterology Vol. 17 (2017) pp. 76
    Online Full Text: dx.doi.org/ (Open Access)
  • Unruhe-Knauf, Britta; Schröder, Elisabeth; Wünsch, Désirée; Knauer, Shirley
    An Old Flame Never Dies : Survivin in Cancer and Cellular Senescence
    In: Gerontology Vol. 62 (2016) Nr. 2, pp. 173 - 181
    Online Full Text: dx.doi.org/
  • Stauber, Roland H.; Hahlbrock, Angelina; Knauer, Shirley; Wünsch, Désirée
    Cleaving for growth : Threonine aspartase 1-a protease relevant for development and disease
    In: The FASEB Journal Vol. 30 (2016) Nr. 3, pp. 1012 - 1022
    Online Full Text: dx.doi.org/
  • Samanta, Krishnananda; Jana, Poulami; Bäcker, Sandra; Knauer, Shirley; Schmuck, Carsten
    Guanidiniocarbonyl pyrrole (GCP) conjugated PAMAM-G2, a highly efficient vector for gene delivery: The importance of DNA condensation
    In: Chemical Communications: ChemComm Vol. 52 (2016) Nr. 84, pp. 12446 - 12449
    Online Full Text: dx.doi.org/
  • Li, Mao; Ehlers, Martin; Schlesiger, Stefanie; Zellermann, Elio; Knauer, Shirley; Schmuck, Carsten
    Incorporation of a Non-Natural Arginine Analogue into a Cyclic Peptide Leads to Formation of Positively Charged Nanofibers Capable of Gene Transfection
    In: Angewandte Chemie International Edition Vol. 55 (2016) Nr. 2, pp. 598 - 601
    Online Full Text: dx.doi.org/
  • Li, Mao; Schlesiger, Stefanie; Knauer, Shirley; Schmuck, Carsten
    Introduction of a tailor made anion receptor into the side chain of small peptides allows fine-tuning the thermodynamic signature of peptide-DNA binding
    In: Organic and Biomolecular Chemistry Vol. 14 (2016) Nr. 37, pp. 8800 - 8803
    Online Full Text: dx.doi.org/
  • Bukhari, Hassan; Kolbe, Katharina; Leonhardt, Gregor; Loosse, Christina; Schröder, Elisabeth; Knauer, Shirley; Marcus, Katrin; Müller, Thorsten
    Membrane tethering of APP c-terminal fragments is a prerequisite for T668 phosphorylation preventing nuclear sphere generation
    In: Cellular Signalling Vol. 28 (2016) Nr. 11, pp. 1725 - 1734
    Online Full Text: dx.doi.org/
  • Schütze, Alexandra; Vogeley, Christian; Gorges, Tobias; Twarock, Sören; Butschan, Jonas; Babayan, Anna; Klein, Diana; Knauer, Shirley; Metzen, Eric; Müller, Volkmar; Jendrossek, Verena; Pantel, Klaus; Milde-Langosch, Karin; Fischer, Jens W.; Röck, Katharina
    RHAMM splice variants confer radiosensitivity in human breast cancer cell lines
    In: OncoTarget Vol. 7 (2016) Nr. 16, pp. 21428 - 21440
    Online Full Text: dx.doi.org/ (Open Access)
  • Wünsch, Désirée; Angelina, Hahlbrock; Jung, Sascha; Schirmeister, Tanja; van den Boom, Johannes; Schilling, Oliver; Knauer, Shirley; Stauber, Roland H.
    Taspase1 : a 'misunderstood' protease with translational cancer relevance
    In: Oncogene Vol. 35 (2016) Nr. 26, pp. 3351 - 3364
    Online Full Text: dx.doi.org/
  • Li, Mao; Schlesiger, Stefanie; Knauer, Shirley; Schmuck, Carsten
    A Tailor-Made Specific Anion-Binding Motif in the Side Chain Transforms a Tetrapeptide into an Efficient Vector for Gene Delivery
    In: Angewandte Chemie International Edition Vol. 54 (2015) Nr. 10, pp. 2941 - 2944
    Online Full Text: dx.doi.org/
  • Wünsch, Désirée; Hahlbrock, Angelina; Heiselmayer, Christina; Bäcker, Sandra; Schrenk, Christian; Benne, Franziska; Schilling, Oliver; Knauer, Shirley
    Evolutionary divergence of Threonine Aspartase1 leads to species-specific substrate recognition
    In: Biological Chemistry Vol. 396 (2015) Nr. 4, pp. 367 - 376
    Online Full Text: dx.doi.org/
  • Wünsch, Désirée; Hahlbrock, Angelina; Heiselmayer, Christina; Bäcker, Sandra; Heun, Patrick; Gösswein, Dorothee; Stöcker, Walter; Schirmeister, Tanja; Schneider, Günter; Krämer, Oliver H.; Knauer, Shirley; Stauber, Roland H.
    Fly versus man : Evolutionary impairment of nucleolar targeting affects the degradome of Drosophila's Taspase1
    In: The FASEB Journal Vol. 29 (2015) Nr. 5, pp. 1973 - 1985
    Online Full Text: dx.doi.org/
  • Docter, Dominic; Strieth, Sebastian; Westmeier, Dana; Hayden, Oliver; Gao, Mingyuan; Knauer, Shirley; Stauber, Roland H.
    No king without a crown – impact of the nanomaterial-protein corona on nanobiomedicine
    In: Nanomedicine: Nanotechnology, Biology, and Medicine Vol. 10 (2015) Nr. 3, pp. 503 - 519
    Online Full Text: dx.doi.org/
  • Wagner, Tobias; Kiweler, Nicole; Wolff, Katharina; Knauer, Shirley; Brandl, André; Hemmerich, Peter; Dannenberg, Jan-Hermen; Heinzel, Thorsten; Schneider, Günther; Krämer, Oliver H.
    Sumoylation of HDAC2 promotes NF-κB-dependent gene expression
    In: OncoTarget Vol. 6 (2015) Nr. 9, pp. 7123 - 7135
    Online Full Text: dx.doi.org/ (Open Access)
  • Knauer, Shirley; Mahendrarajah, Nisintha; Roos, Wynand P.; Krämer, Oliver H.
    The inducible E3 ubiquitin ligases SIAH1 and SIAH2 perform critical roles in breast and prostate cancers
    In: Cytokine & Growth Factor Reviews Vol. 26 (2015) Nr. 4, pp. 405 - 413
    Online Full Text: dx.doi.org/
  • Docter, Dominic; Westmeier, Dana; Markiewicz, Marta; Stolte, Stefan; Knauer, Shirley; Stauber, Roland H.
    The nanoparticle biomolecule corona : lessons learned – challenge accepted?
    In: Chemical Society Reviews Vol. 44 (2015) Nr. 17, pp. 6094 - 6121
    Online Full Text: dx.doi.org/ (Open Access)
  • Althoff, Kristina; Lindner, Sven; Odersky, Andrea; Mestdagh, Pieter; Beckers, Anneleen; Karczewski, Sarah; Molenaar, Jan J; Bohrer, Anna; Knauer, Shirley; Speleman, Frank; Epple, Matthias; Kozlova, Diana; Yoon, Sena; Baek, Kwanghee; Vandesompele, Jo; Eggert, Angelika; Schramm, Alexander; Schulte, Johannes
    miR-542-3p exerts tumor suppressive functions in neuroblastoma by downregulating Survivin
    In: International Journal of Cancer Vol. 136 (2015) Nr. 6, pp. 1308 - 1320
    Online Full Text: dx.doi.org/ (Open Access)
  • Dördelmann, Gregor; Kozlova, Diana; Karczewski, Sarah; Lizio, Rosario; Knauer, Shirley; Epple, Matthias
    Calcium phosphate increases the encapsulation efficiency of hydrophilic drugs (proteins, nucleic acids) into poly(D,L-lactide-co-glycolide acid) nanoparticles for intracellular delivery
    In: Journal of Materials Chemistry B: Materials for Biology and Medicine Vol. 2 (2014) Nr. 41, pp. 7250 - 7259
    Online Full Text: dx.doi.org/ (Open Access)
  • van den Boom, Johannes; Mamic, Marija; Baccelliere, Daniele; Zweerink, Susanne; Kaschani, Farnusch; Knauer, Shirley; Bayer, Peter; Kaiser, Markus
    Peptidyl succinimidyl peptides as taspase 1 inhibitors
    In: ChemBioChem Vol. 15 (2014) Nr. 15, pp. 2233 - 2237
    Online Full Text: dx.doi.org/
  • Docter, Dominic; Distler, Ute; Storck, Wiebke; Kuharev, Jörg; Wünsch, Desirée; Hahlbrock, Angelina; Knauer, Shirley K.; Tenzer, Stefan; Stauber, Roland H.
    Quantitative profiling of the protein coronas that form around nanoparticles
    In: Nature Protocols Vol. 9 (2014) Nr. 9, pp. 2030 - 2044
    Online Full Text: dx.doi.org/
  • Knauer, Shirley; Unruhe-Knauf, Britta; Karczewski, Sarah; Hecht, Rouven; Fetz, Verena; Bier, Carolin; Friedl, Sandra; Wollenberg, Barbara; Pries, Ralph; Habtemichael, Negusse; Heinrich, Ulf-Rüdiger; Stauber, Roland H.
    Functional Characterization of Novel Mutations Affecting Survivin (BIRC5)-Mediated Therapy Resistance in Head and Neck Cancer Patients
    In: Human Mutation Vol. 34 (2013) Nr. 2, pp. 395 - 404
    Online Full Text: dx.doi.org/
  • Tenzer, Stefan; Docter, Dominic; Kuharev, Jörg; Musyanovych, Anna; Fetz, Verena; Hecht, Rouven; Schlenk, Florian; Fischer, Dagmar; Kiouptsi, Klytaimnistra; Reinhardt, Christoph; Landfester, Katharina; Schild, Hansjörg; Maskos, Michael; Knauer, Shirley; Stauber, Roland H.
    Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology
    In: Nature Nanotechnology Vol. 8 (2013) Nr. 10, pp. 772 - 781
    Online Full Text: dx.doi.org/
  • Krämer, Oliver H.; Stauber, Roland H.; Bug, Gesine; Hartkamp, Jörg; Knauer, Shirley
    SIAH proteins : Critical roles in leukemogenesis
    In: Leukemia Vol. 27 (2013) Nr. 4, pp. 792 - 802
    Online Full Text: dx.doi.org/
  • Stauber, Roland H.; Knauer, Shirley
    Taspase1 : Lizenz zum Schneiden
    In: Biospektrum Vol. 19 (2013) Nr. 2, pp. 134 - 136
    Online Full Text: dx.doi.org/
  • Kuchelmeister, Hannes Y.; Karczewski, Sarah; Gutschmidt, Aljona; Knauer, Shirley; Schmuck, Carsten
    Utilizing Combinatorial Chemistry and Rational Design : Peptidic Tweezers with Nanomolar Affinity to DNA Can Be Transformed into Efficient Vectors for Gene Delivery by Addition of a Lipophilic Tail
    In: Angewandte Chemie International Edition Vol. 52 (2013) Nr. 52, pp. 14016 - 14020
    Online Full Text: dx.doi.org/
  • Stauber, Roland H.; Knauer, Shirley; Habtemichael, Negusse; Bier, Carolin; Unruhe-Knauf, Britta; Weisheit, Simona; Spange, Stephanie; Nonnenmacher, Frank; Fetz, Verena; Ginter, Torsten; Reichardt, Sigrid; Liebmann, Claus; Schneider, Günther; Krämer, Oliver H.
    A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancer
    In: OncoTarget Vol. 3 (2012) Nr. 1, pp. 31 - 43
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Bier, Carolin; Knauer, Shirley; Wünsch, Désirée; Kunst, Lena; Scheiding, Sabine; Kaiser, Markus; Ottmann, Christian; Krämer, Oliver H.; Stauber, Roland H.
    Allosteric inhibition of Taspase1's pathobiological activity by enforced dimerization in vivo
    In: The FASEB Journal Vol. 26 (2012) Nr. 8, pp. 3421 - 3429
    Online Full Text: dx.doi.org/
  • Wünsch, Désirée; Fetz, Verena; Heider, Dominik; Tenzer, Stefan; Bier, Carolin; Kunst, Lena; Knauer, Shirley; Stauber, Roland H.
    Chemico-genetic strategies to inhibit the leukemic potential of threonine aspartase-1
    In: Blood Cancer Journal Vol. 2 (2012) Nr. 6, pp. e77
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Pietschmann, Kristin; Buchwald, Marc; Müller, Sylvia; Knauer, Shirley; Kögl, Manfred; Heinzl, Thorsten; Krämer, Oliver H.
    Differential regulation of PML–RARα stability by the ubiquitin ligases SIAH1/SIAH2 and TRIAD1
    In: The International Journal of Biochemistry & Cell Biology Vol. 44 (2012) Nr. 1, pp. 132 - 138
    Online Full Text: dx.doi.org/
  • Schröder, Elisabeth; Gebel, Lena; Eremeev, Andrey A.; Morgner, Jessica; Grum, Daniel; Knauer, Shirley; Bayer, Peter; Müller, Jonathan W.
    Document Human PAPS synthase isoforms are dynamically regulated enzymes with access to nucleus and cytoplasm
    In: PLoS ONE Vol. 7 (2012) Nr. 1, pp. e29559
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Brandl, André; Wagner, Tobias; Uhlig, Katharina M.; Knauer, Shirley; Stauber, Roland H.; Melchior, Frauke; Schneider, Günther; Heinzel, Thorsten; Krämer, Oliver H.
    Dynamically regulated sumoylation of HDAC2 controls p53 deacetylation and restricts apoptosis following genotoxic stress
    In: Journal of Molecular Cell Biology Vol. 4 (2012) Nr. 5, pp. 284 - 293
    Online Full Text: dx.doi.org/ (Open Access)
  • Kuchelmeister, Hannes Y.; Gutschmidt, Aljona; Tillmann, Sarah; Knauer, Shirley; Schmuck, Carsten
    Efficient gene delivery into cells by a surprisingly small three-armed peptide ligand
    In: Chemical Science Vol. 3 (2012) Nr. 4, pp. 996 - 1002
    Online Full Text: dx.doi.org/
  • Ginter, Torsten; Bier, Carolin; Knauer, Shirley; Sughra, Kalsoom; Hildebrand, Dagmar; Münz, Tobias; Liebe, Theresa; Heller, Regine; Henke, Andreas; Stauber, Roland H.; Reichardt, Werner; Schmid, Johannes A.; Kubatzky, Katharina F.; Heinzel, Thorsten; Krämer, Oliver H.
    Histone deacetylase inhibitors block IFNγ-induced STAT1 phosphorylation
    In: Cellular Signalling Vol. 24 (2012) Nr. 7, pp. 1453 - 1460
    Online Full Text: dx.doi.org/
  • Gebauer, Julia Susanne; Malissek, Marcelina; Simon, Sonja; Knauer, Shirley; Maskos, Michael; Stauber, Roland H.; Peukert, Wolfgang; Treuel, Lennart
    Impact of the nanoparticle-protein corona on colloidal stability and protein structure
    In: Langmuir Vol. 28 (2012) Nr. 25, pp. 9673 - 9679
    Online Full Text: dx.doi.org/
  • Bier, Carolin; Hecht, Rouven; Kunst, Lena; Scheiding, Sabine; Wünsch, Désirée; Goesswein, Dorothée; Schneider, Günther; Krämer, Oliver H.; Knauer, Shirley; Stauber, Roland H.
    Overexpression of the Catalytically Impaired Taspase1T234V or Taspase1D233A Variants Does Not Have a Dominant Negative Effect in T(4;11) Leukemia Cells
    In: PLoS ONE Vol. 7 (2012) Nr. 5, pp. e34142
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Stauber, Roland H.; Bier, Carolin; Knauer, Shirley
    Targeting Taspase1 for Cancer Therapy—Letter
    In: Cancer Research Vol. 72 (2012) Nr. 11, pp. 2912
    Online Full Text: dx.doi.org/
  • Knauer, Shirley; Fetz, Verena; Rabenstein, Jens; Friedl, Sandra; Hofmann, Bettina; Sabiani, Samaneh; Schröder, Elisabeth; Kunst, Lena; Proschak, Eugen; Thines, Eckhard; Kindler, Thomas; Schneider, Gisbert; Marschalek, Rolf; Stauber, Roland; Bier, Carolin
    Bioassays to Monitor Taspase1 Function for the Identification of Pharmacogenetic Inhibitors.
    In: PLoS ONE Vol. 6 (2011) Nr. 5, pp. e18253
    Online Full Text: dx.doi.org/ (Open Access)
  • Bier, Carolin; Knauer, Shirley; Klapthor, Alexander; Schweitzer, Andrea; Rekik, Alexander; Krämer, Oliver; Marschalek, Rolf; Stauber, Roland
    Cell-based analysis of structure-function activity of threonine aspartase 1.
    In: The Journal of Biological Chemistry (JBC) Vol. 286 (2011) Nr. 4, pp. 3007 - 3017
    Online Full Text: dx.doi.org/
  • Tenzer, Stefan; Docter, Dominic; Rosfa, Susanne; Wlodarski, Alexandra; Kuharev, Jörg; Rekik, Alexander; Knauer, Shirley; Bantz, Christoph; Nawroth, Thomas; Bier, Carolin; Sirirattanapan, Jarinratn; Mann, Wolf; Treuel, Lennart; Zellner, Reinhard; Maskos, Michael; Schild, Hansjörg; Stauber, Roland H.
    Nanoparticle size is a critical physicochemical determinant of the human blood plasma corona : a comprehensive quantitative proteomic analysis
    In: ACS Nano Vol. 5 (2011) Nr. 9, pp. 7155 - 7167
    Online Full Text: dx.doi.org/
  • Bier, Carolin; Knauer, Shirley; Docter, Dominic; Schneider, Gisbert; Krämer, Oliver; Stauber, Roland
    The Importin-Alpha/Nucleophosmin Switch Controls Taspase1 Protease Function.
    In: Traffic: The International Journal of Intracellular Transport Vol. 12 (2011) Nr. 6, pp. 703 - 714
    Online Full Text: dx.doi.org/
  • Pless, Birgit; Oehm, Clarissa; Knauer, Shirley; Stauber, Roland; Dingermann, Theo; Marschalek, Rolf
    The heterodimerization domains of MLL-FYRN and FYRC-are potential target structures in t(4;11) leukemia.
    In: Leukemia Vol. 25 (2011) Nr. 4, pp. 663 - 670
    Online Full Text: dx.doi.org/
  • Knauer, Shirley; Heinrich, Ulf-Rüdiger; Bier, Carolin; Habtemichael, Negusse; Docter, Dominic; Helling, Kai; Mann, Wolf; Stauber, Roland
    An otoprotective role for the apoptosis inhibitor protein survivin
    In: Cell Death and Disease Vol. 1 (2010) Nr. 51, e51
    Online Full Text: dx.doi.org/ (Open Access)
  • Stauber, Roland H.; Wünsch, Desiree; Knauer, Shirley; Fetz, Verena
    An update on the pathobiological relevance of nuclear receptors for cancers of the head and neck
    In: Histology and Histopathology Vol. 25 (2010) Nr. 8, pp. 1093 - 1104
    Online Full Text: dx.doi.org/
  • Habtemichael, Negusse; Wünsch, Desiree; Bier, Carolin; Tillmann, Sarah; Unruhe-Knauf, Britta; Frauenknecht, Katrin; Heinrich, Ulf-Rüdiger; Mann, Wolf J.; Stauber, Roland H.; Knauer, Shirley
    Cloning and functional characterization of the guinea pig apoptosis inhibitor protein Survivin
    In: Gene Vol. 469 (2010) Nr. 1-2, pp. 9 - 17
    Online Full Text: dx.doi.org/
  • Habtemichael, Negusse; Heinrich, Ulf-Rüdiger; Knauer, Shirley; Schmidtmann, Irene; Bier, Carolin; Docter, Dominic; Brochhausen, Christoph; Helling, Kai; Brieger, Jürgen; Stauber, Roland H.; Mann, Wolf J.
    Expression analysis suggests a potential cytoprotective role of Birc5 in the inner ear
    In: Molecular and Cellular Neuroscience (MCN) Vol. 45 (2010) Nr. 3, pp. 297 - 305
    Online Full Text: dx.doi.org/
  • Schweitzer, Andrea; Knauer, Shirley; Stauber, Roland H.
    Nuclear receptors in head and neck cancer: current knowledge and perspectives.
    In: International Journal of Cancer Vol. 126 (2010) Nr. 4, pp. 801 - 809
    Online Full Text
  • Krämer, Oliver H.; Knauer, Shirley; Greiner, Georg; Jandt, Enrico; Reichardt, Sigrid; Gührs, Karl-Heinz; Stauber, Roland H.; Böhmer, Frank D.; Heinzel, Thorsten
    A phosphorylation-acetylation switch regulates STAT1 signaling.
    In: Genes & development : a journal of cellular and molecular biology Vol. 23 (2009) Nr. 2, pp. 223 - 235
    Online Full Text
  • Fetz, Verena; Bier, Carolin; Habtechmichel, Negusse; Schuon, Robert; Schweitzer, Andrea; Engels, Knut; Kovács, Adorjan F.; Schneider, Sandra; Mann, Wolf; Stauber, Roland H.; Knauer, Shirley
    Inducible NO synthase confers chemoresistance in head and neck cancer by modulating survivin
    In: International Journal of Cancer Vol. 124 (2009) Nr. 9, pp. 2033 - 2041
    Online Full Text
  • Knauer, Shirley
    Prognostic and therapeutic potential of nuclear receptors in head and neck squamous cell carcinomas.
    In: Journal of Oncology (2009) 349205
    Online Full Text: dx.doi.org/
  • Pautz, Andrea; Linker, Katrin; Altenhöfer, Sebastian; Heil, Sebastian; Schmidt, Nadine; Art, Julia; Knauer, Shirley; Stauber, Roland; Sadri, Navid; Pont, Adam; Schneider, Robert J.; Kleinert, Hartmut
    Similar regulation of human inducible nitric oxide synthase (iNOS) expression by different isoforms of the RNA binding protein AUF1
    In: The Journal of Biological Chemistry (JBC) Vol. 284 (2009) Nr. 5, pp. 2755 - 2766
    Online Full Text
  • Fetz, Verena; Knauer, Shirley; Bier, Carolin; Von Kries, Jens Peter; Stauber, Roland H.
    Translocation biosensors – cellular system integrators to dissect CRM1-dependent nuclear export by chemicogenomics.
    In: Sensors Vol. 9 (2009) Nr. 7, pp. 5423 - 5445
    Online Full Text: dx.doi.org/ (Open Access)
  • Krämer, Oliver H.; Zimmermann, D.; Knauer, Shirley; Stauber, Roland H.; Heinzel, Thorsten
    Histone deacetylase inhibitors and hydroxyurea modulate the cell cycle and cooperatively induce apoptosis.
    In: Oncogene : an international journal Vol. 27 (2008) Nr. 6, pp. 732 - 740
    Online Full Text
  • Engels, Knut; Knauer, Shirley; Loibl, Sibylle; Fetz, Verena; Harter, Philipp; Schweitzer, Andrea; Fisseler-Eckhoff, Annette; Kommoss, Friedrich; Hanker, Lars; Nekljudova, Valentina; Hermanns, Iris; Kleinert, Hartmut; Mann, Wolf; du Bois, Andreas; Stauber, Roland H.
    NO signaling confers cytoprotectivity through the survivin network in ovarian carcinomas
    In: Cancer Research Vol. 68 (2008) Nr. 13, pp. 5159 - 5166
    Online Full Text
  • Garzia, Livia; D'Angelo, Anna; Amoresano, Angela; Knauer, Shirley; Cirulli, Claudia; Campanella, Chiara; Stauber, Roland H.; Steegborn, Clemens; Iolascon, Achille; Zollo, Massimo
    Phosphorylation of nm23-H1 by CKI induces its complex formation with h-prune and promotes cell motility
    In: Oncogene Vol. 27 (2008) Nr. 13, pp. 1853 - 1864
    Online Full Text: dx.doi.org/
  • Schweitzer, Andrea; Knauer, Shirley; Stauber, Roland H.
    Therapeutic potential of nuclear receptors.
    In: Expert Opinion on Therapeutic Patents Vol. 18 (2008) Nr. 8, pp. 861 - 888
    Online Full Text
  • Engels, Knut; Knauer, Shirley; Metzler, D.; Sim, C.; Struschka, O.; Bier, Carolin; Mann, Wolf; Kovács, Adorjan F.; Stauber, Roland H.
    Dynamic Intracellular Survivin as an Early Prognostic Marker in Oral Squamous Cell Carcinomas : Underlying Molecular Mechanism and Potential
    In: The Journal of Pathology Vol. 211 (2007) Nr. 5, pp. 532 - 540
    Online Full Text
  • Lippert, Burkhard M.; Knauer, Shirley; Fetz, Verena; Mann, Wolf; Stauber, Roland H.
    Dynamic survivin in head and neck cancer: Molecular mechanism and therapeutic potential
    In: International Journal of Cancer Vol. 121 (2007) Nr. 6, pp. 1169 - 1174
    Online Full Text
  • Stauber, Roland H.; Mann, Wolf; Knauer, Shirley
    Nuclear and Cytoplasmic Survivin: Molecular Mechanism, Prognostic, and Therapeutic Potential.
    In: Cancer Research Vol. 67 (2007) Nr. 13, pp. 5999 - 6002
    Online Full Text
  • Knauer, Shirley; Krämer, Oliver H.; Knösel, Thomas; Engels, Knut; Rödel, Franz; Kovács, Adorján F.; Dietmaier, Wolfgang; Klein-Hitpaß, Ludger; Habtemichael, Negusse; Schweitzer, Andrea; Brieger, Jürgen; Rödel, Claus; Mann, Wolf; Petersen, Iver; Heinzel, Thorsten; Stauber, Roland H.
    Nuclear export is essential for the tumor-promoting activity of survivin
    In: The FASEB Journal: the official journal of the Federation of American Societies for Experimental Biology / Experimental Biology ; Transforming the future through science ; Chicago, April 22-26, 2017 Vol. 21 (2007) Nr. 1, pp. 207 - 216
    Online Full Text
  • Knauer, Shirley
    Survivin's Dual Role - An Export's View.
    In: Cell Cycle Vol. 6 (2007) Nr. 5, pp. 518 - 521
    Online Full Text
  • Capalbo, Gianni; Rödel, Claus; Stauber, Roland H.; Knauer, Shirley; Bache, Matthias; Kappler, Matthias; Rödel, Franz
    The Role of Survivin for Radiation Therapy : Prognostic and Predictive Factor and Therapeutic Target
    In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Vol. 183 (2007) Nr. 11, pp. 593 - 599
    Online Full Text: dx.doi.org/
  • Seil, Inka; Frei, Claudia; Sültmann, Holger; Knauer, Shirley; Engels, Knut; Jäger, Elke; Zatloukal, Kurt; Pfreundschuh, Michael; Knuth, Alexander; Tseng-Chen, Yao; Jungbluth, Achim A.; Stauber, Roland H.; Jäger, Dirk
    The differentiation antigen NY-BR-1 is a potential target for antibody based therapies in breast cancer.
    In: International Journal of Cancer Vol. 120 (2007) Nr. 12, pp. 2635 - 2642
    Online Full Text
  • Knauer, Shirley; Bier, Carolin; Schlag, Peter; Fritzmann, Johannes; Dietmaier, Wolfgang; Rödel, Franz; Klein-Hitpaß, Ludger; Kovács, Adoriàn F.; Döring, Claudia; Hansmann, Martin-Leo; Hofmann, Wolf-Karsten; Kunkel, Martin; Brochhausen, Christoph; Engels, Knut; Lippert, Burkhard M.; Mann, Wolf; Stauber, Roland H.
    The survivin splice variant survivin-3B is cytoprotective and can function as a chromosomal passenger complex protein
    In: Cell Cycle Vol. 6 (2007) Nr. 12, pp. 1502 - 1509
    Online Full Text: dx.doi.org/
  • Krämer, Oliver H.; Baus, Daniela; Knauer, Shirley; Stein, Stefan; Jäger, Elke; Stauber, Roland H.; Grez, Manuel; Pfitzner, Edith; Heinzel, Thorsten
    Acetylation of Stat1 modulates NF-kB activity
    In: Genes & development : a journal of cellular and molecular biology Vol. 20 (2006) Nr. 4, pp. 473 - 485
    Online Full Text
  • Stauber, Roland H.; Rabenhorst, Uta; Rekik, Alexander; Engels, Knut; Bier, Carolin; Knauer, Shirley
    Nucleocytoplasmic shuttling and the biological activity of mouse survivin are regulated by an active nuclear export signal
    In: Traffic: The International Journal of Intracellular Transport Vol. 7 (2006) Nr. 11, pp. 1461 - 1472
    Online Full Text: dx.doi.org/
  • Dälken, Benjamin; Giesübel, Ulrike; Knauer, Shirley; Wels, Winfried
    Targeted induction of apoptosis by chimeric granzyme B fusion proteins carrying antibody and growth factor domains for cell recognition.
    In: Cell death & differentiation : D & D ; cdd Vol. 13 (2006) Nr. 4, pp. 576 - 585
    Online Full Text
  • Knauer, Shirley; Bier, Carolin; Habtemichael, Negusse; Stauber, Roland H.
    The Survivin-Crm1 interaction is essential for chromosomal passenger complex localization and function.
    In: EMBO Reports Vol. 7 (2006) Nr. 12, pp. 1259 - 1265
    Online Full Text
  • Knauer, Shirley; Stauber, Roland H.
    Development of an autofluorescent translocation biosensor system to investigate protein-protein interactions in living cells
    In: Analytical Chemistry Vol. 77 (2005) Nr. 15, pp. 4815 - 4820
    Online Full Text: dx.doi.org/
  • Knauer, Shirley; Carra, Gert; Stauber, Roland H.
    Nuclear Export Is Evolutionarily Conserved in CVC Paired-Like Homeobox Proteins and Influences Protein Stability, Transcriptional Activation, and Extracellular Secretion.
    In: Molecular and Cellular Biology (MCB) Vol. 6 (2005) Nr. 7, pp. 594 - 606
    Online Full Text
  • Knauer, Shirley; Moodt, Sabrina; Berg, Thorsten; Liebel, Urban; Pepperkok, Rainer; Stauber, Roland H.
    Translocation Biosensors to Study Signal-Specific Nucleo-Cytoplasmic Transport, Protease Activity and Protein–Protein Interactions
    In: Traffic: The International Journal of Intracellular Transport Vol. 6 (2005) Nr. 7, pp. 594 - 606

    Book articles / Proceedings papers

  • Fetz, Verena; Stauber, Roland H.; Knauer, Shirley
    Translocation Biosensors—Versatile Tools to Probe Protein Functions in Living Cells
    In: High Content Screening 2018, pp. 195 - 210
    Online Full Text: dx.doi.org/
  • Unruhe-Knauf, Britta; Knauer, Shirley
    Analysis of HDACi-induced changes in chromosomal passenger complex localization
    In: HDAC/HAT Function Assessment and Inhibitor Development: Methods and Protocols / Krämer, Oliver H. (Eds.) 2017, pp. 47 - 59
    Online Full Text: dx.doi.org/
  • Knauer, Shirley; Westmeier, Dana; Stauber, Roland; Docter, Dominic
    Bio-Nano Interactions
    In: Adverse effects of engineered nanomaterials: exposure, toxicology, and impact on human health / Fadeel, Bengt; Pietroiusti, Antonio; Shvedova, Anna (Eds.) 2017, pp. 1 - 12
    Online Full Text: dx.doi.org/

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