Publications
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Functional Linkers Support Targeting of Multivalent Tweezers to Taspase1In: Chemistry - A European Journal Vol. 30 (2024) Nr. 56, e202401542Online Full Text: dx.doi.org/ (Open Access)
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Merging of a Supramolecular Ligand with a Switchable Luminophore : Light-Responsiveness, Photophysics and BioimagingIn: Chemistry - A European Journal (2024) e202402578 in pressOnline Full Text: dx.doi.org/ (Open Access)
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Old Passengers as New Drivers : Chromosomal Passenger Proteins Engage in Translesion SynthesisIn: Cells Vol. 13 (2024) Nr. 21, 1804Online Full Text: dx.doi.org/ (Open Access)
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Synergetic Enhancing Effects between Platinum Nanosensitizers and Clinically Approved Stabilizing Ligands in Proton Therapy, Causing High-Yield Double-Strand Breaks of Plasmid DNA at Relevant DoseIn: Advanced NanoBiomed Research (2024) in pressOnline Full Text: dx.doi.org/ (Open Access)
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A Fluorophore-Labeled Lysine Dendrimer with an Oxo-Anion-Binding Motif for Tracking Gene TransfectionIn: ChemBioChem Vol. 24 (2023) Nr. 15, e202300296Online Full Text: dx.doi.org/ (Open Access)
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Cationic Solution and Solid‐state Emitters : Robust Imaging Agents for Cells, Bacteria and ProtistsIn: Chemistry - A European Journal Vol. 29 (2023) Nr. 38, e202300334Online Full Text: dx.doi.org/ (Open Access)
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Deoxyestrone-based lipofection agents with solution- and solid-state emission propertiesIn: Organic and Biomolecular Chemistry Vol. 21 (2023) pp. 5762 - 5767Online Full Text: dx.doi.org/ (Open Access)
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Exploiting Vitamin D Receptor and Its Ligands to Target Squamous Cell Carcinomas of the Head and NeckIn: International Journal of Molecular Sciences (IJMS) Vol. 24 (2023) Nr. 5, 4675Online Full Text: dx.doi.org/ (Open Access)
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Impact of Peptide Sequences on Their Structure and Function : Mimicking of Virus-Like Nanoparticles for Nucleic Acid DeliveryIn: ChemBioChem Vol. 24 (2023) Nr. 1, e202200519Online Full Text: dx.doi.org/ (Open Access)
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Potentiating Tweezer Affinity to a Protein Interface with Sequence-Defined Macromolecules on NanoparticlesIn: Biomacromolecules Vol. 24 (2023) Nr. 8, pp. 3666 - 3679Online Full Text: dx.doi.org/
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Taspase1 facilitates Topoisomerase IIβ-mediated DNA double-strand breaks driving estrogen-induced transcriptionIn: Cells Vol. 2023 (2023) Nr. 12, 363Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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The Apoptosis Inhibitor Protein Survivin Is a Critical Cytoprotective Resistor against Silica-Based NanotoxicityIn: Nanomaterials Vol. 13 (2023) Nr. 18, 2546Online Full Text: dx.doi.org/ (Open Access)
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Tuning Nanobodies’ Bioactivity : Coupling to Ultrasmall Gold Nanoparticles Allows the Intracellular Interference with SurvivinIn: Small Vol. 19 (2023) Nr. 33, 2300871 10.1002/smll.202300871Online Full Text: dx.doi.org/ (Open Access)
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A Bivalent Supramolecular GCP Ligand Enables Blocking of the Taspase1/Importin α InteractionIn: ChemMedChem Vol. 17 (2022) Nr. 1, e202100640Online Full Text: dx.doi.org/ (Open Access)
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Advances towards Cell‐Specific Gene Transfection : A Small‐Molecule Approach Allows Order‐of‐Magnitude SelectivityIn: Chemistry - A European Journal Vol. 28 (2022) Nr. 43, e202202024Online Full Text: dx.doi.org/; Online Full Text: dx.doi.org/ (Open Access)
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Computational model predicts protein binding sites of a luminescent ligand equipped with guanidiniocarbonyl-pyrrole groupsIn: Beilstein Journal of Organic Chemistry Vol. 18 (2022) pp. 1322 - 1331Online Full Text: dx.doi.org/ (Open Access)
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Dual activity inhibition of threonine aspartase 1 by a single bisphosphate ligandIn: RSC Advances Vol. 12 (2022) Nr. 53, pp. 34176 - 34184Online Full Text: dx.doi.org/ (Open Access)
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GGDEF domain as spatial on-switch for a phosphodiesterase by interaction with landmark protein HubPIn: npj Biofilms and Microbiomes Vol. 8 (2022) Nr. 1, 35Online Full Text: dx.doi.org/ (Open Access)
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Impact of Secretion-Active Osteoblast-Specific Factor 2 in Promoting Progression and Metastasis of Head and Neck CancerIn: Cancers Vol. 14 (2022) Nr. 9, 2337Online Full Text: dx.doi.org/ (Open Access)
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Recognition of a Flexible Protein Loop in Taspase 1 by Multivalent Supramolecular TweezersIn: Biomacromolecules Vol. 23 (2022) Nr. 11, pp. 4504 - 4518Online Full Text: dx.doi.org/
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Selective Disruption of Survivin's Protein-Protein Interactions : A Supramolecular Approach Based on GuanidiniocarbonylpyrroleIn: ChemBioChem Vol. 23 (2022) Nr. 5, e202100618Online Full Text: dx.doi.org/ (Open Access)
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The Taspase1/Myosin1f-axis regulates filopodia dynamicsIn: iScience Vol. 25 (2022) Nr. 6, 104355Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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The Vitamin D Receptor–BIM Axis Overcomes Cisplatin Resistance in Head and Neck CancerIn: Cancers Vol. 14 (2022) Nr. 20, 5131Online Full Text: dx.doi.org/ (Open Access)
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Amyloid precursor protein elevates fusion of promyelocytic leukemia nuclear bodies in human hippocampal areas with high plaque loadIn: Acta Neuropathologica Communications Vol. 9 (2021) Nr. 1, pp. 66Online Full Text: dx.doi.org/ (Open Access)
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Luminescent Amphiphilic Aminoglycoside Probes to Study TransfectionIn: ChemBioChem Vol. 22 (2021) Nr. 9, pp. 1563 - 1567Online Full Text: dx.doi.org/ (Open Access)
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New tools to probe the protein surface : Ultrasmall gold nanoparticles carry amino acid bindersIn: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry Vol. 125 (2021) Nr. 1, pp. 115 - 127Online Full Text: dx.doi.org/ (Open Access)
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PEGylated sequence-controlled macromolecules using supramolecular binding to target the Taspase1/Importin α interactionIn: Chemical Communications: ChemComm Vol. 57 (2021) Nr. 25, pp. 3091 - 3094Online Full Text: dx.doi.org/ (Open Access)
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Specific inhibition of the Survivin–CRM1 interaction by peptide-modified molecular tweezersIn: Nature Communications Vol. 12 (2021) Nr. 1, pp. 1505Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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TNF-α-Inhibition Improves the Biocompatibility of Porous Polyethylene Implants In VivoIn: Tissue Engineering and Regenerative Medicine Vol. 18 (2021) Nr. 2, pp. 297 - 303Online Full Text: dx.doi.org/ (Open Access)
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Umbelliferone Decorated Water-soluble Zinc(II) Phthalocyanines : In Vitro Phototoxic Antimicrobial Anti-cancer AgentsIn: Chemistry - A European Journal Vol. 27 (2021) Nr. 59, pp. 14672 - 14680Online Full Text: dx.doi.org/ (Open Access)
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A Supramolecular Stabilizer of the 14-3-3ζ/ERα Protein-Protein Interaction with a Synergistic Mode of ActionIn: Angewandte Chemie International Edition Vol. 132 (2020) Nr. 13, pp. 5322 - 5325Online Full Text: dx.doi.org/ (Open Access)
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Boosting nanotoxicity to combat multidrug-resistant bacteria in pathophysiological environmentsIn: Nanoscale Advances Vol. 2 (2020) Nr. 11, pp. 5428 - 5440Online Full Text: dx.doi.org/ (Open Access)
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Cancer-Cell-Specific Drug Delivery by a Tumor-Homing CPP-Gossypol Conjugate Employing a Tracelessly Cleavable LinkerIn: Chemistry - A European Journal Vol. 26 (2020) Nr. 14, pp. 3010 - 3015Online Full Text: dx.doi.org/ (Open Access)
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Erratum : Nanoparticle binding attenuates the pathobiology of gastric cancer-associated: Helicobacter pyloriIn: Nanoscale Vol. 12 (2020) Nr. 3, pp. 2154 - 2155Online Full Text: dx.doi.org/ (Open Access)
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Functional Disruption of the Cancer-Relevant Interaction between Survivin and Histone H3 with a Guanidiniocarbonyl Pyrrole LigandIn: Angewandte Chemie International Edition Vol. 59 (2020) Nr. 14, pp. 5567 - 5571Online Full Text: dx.doi.org/ (Open Access)
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Lipofection with estrone-based luminophores featuring aggregation-induced emission propertiesIn: RSC Advances Vol. 10 (2020) Nr. 33, pp. 19643 - 19647Online Full Text: dx.doi.org/ (Open Access)
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Mechanisms of nanotoxicity – biomolecule coronas protect pathological fungi against nanoparticle-based eradicationIn: Nanotoxicology Vol. 14 (2020) Nr. 9, pp. 1157 - 1174Online Full Text: dx.doi.org/
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Smart Glycopolymeric Nanoparticles for Multivalent Lectin Binding and Stimuli-Controlled Guest ReleaseIn: Biomacromolecules Vol. 21 (2020) Nr. 6, pp. 2356 - 2364Online Full Text: dx.doi.org/
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Supramolecular subphthalocyanine complexes-cellular uptake and phototoxicityIn: Chemical Communications: ChemComm Vol. 56 (2020) Nr. 55, pp. 7653 - 7656Online Full Text: dx.doi.org/
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The other side of the corona : Nanoparticles inhibit the protease taspase1 in a size-dependent mannerIn: Nanoscale Vol. 12 (2020) Nr. 37, pp. 19093 - 19103Online Full Text: dx.doi.org/
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A Branched Tripeptide with an Anion-Binding Motif as a Novel Delivery Carrier for Efficient Gene TransfectionIn: ChemBioChem Vol. 20 (2019) Nr. 11, pp. 1410 - 1416Online Full Text: dx.doi.org/
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Arginine mimetic appended peptide-based probes for fluorescence turn-on detection of 14-3-3 proteinsIn: Organic and Biomolecular Chemistry Vol. 17 (2019) Nr. 17, pp. 4359 - 4363Online Full Text: dx.doi.org/
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Biomolecule-corona formation confers resistance of bacteria to nanoparticle-induced killing : Implications for the design of improved nanoantibioticsIn: Biomaterials Vol. 192 (2019) pp. 551 - 559Online Full Text: dx.doi.org/
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Is small smarter? Nanomaterial-based detection and elimination of circulating tumor cells : Current knowledge and perspectivesIn: International Journal of Nanomedicine Vol. 14 (2019) pp. 4187 - 4209Online Full Text: dx.doi.org/ (Open Access)
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Non-viral transfection vectors : Are hybrid materials the way forward?In: MedChemComm Vol. 10 (2019) Nr. 10, pp. 1692 - 1718Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Protein Dimerization Probed with Site-Specific Attached Single NanoparticlesIn: Biophysical Journal Vol. 116 (2019) Nr. 3, Suppl. 1, pp. 284aOnline Full Text: dx.doi.org/ (Open Access)
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REMOVED: Breaking resistance to nanoantibiotics by overriding corona-dependent inhibition using a pH-switchIn: Materials Today Vol. 26 (2019) pp. 19 - 29Online Full Text: dx.doi.org/ (Open Access)
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Resistance to Nano-Based Antifungals Is Mediated by Biomolecule CoronasIn: ACS Applied Materials & Interfaces Vol. 11 (2019) Nr. 1, pp. 104 - 114Online Full Text: dx.doi.org/
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A dipeptide with enhanced anion binding affinity enables cell uptake and protein deliveryIn: Organic and Biomolecular Chemistry Vol. 16 (2018) Nr. 13, pp. 2312 - 2317Online Full Text: dx.doi.org/
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Expressional analysis of disease-relevant signalling-pathways in primary tumours and metastasis of head and neck cancers.In: Scientific Reports Vol. 8 (2018) Nr. 1, pp. 7326Online Full Text: dx.doi.org/ (Open Access)
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Formation of Twisted β-Sheet Tapes from a Self-Complementary Peptide Based on Novel Pillararene-GCP Host–Guest Interaction with Gene Transfection PropertiesIn: Chemistry - A European Journal Vol. 24 (2018) Nr. 39, pp. 9754 - 9759Online Full Text: dx.doi.org/
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From Supramolecular Vesicles to Micelles : Controllable Construction of Tumor-Targeting Nanocarriers Based on Host–Guest Interaction between a Pillar[5]arene-Based Prodrug and a RGD-Sulfonate GuestIn: Small Vol. 14 (2018) Nr. 52, pp. 1803952Online Full Text: dx.doi.org/
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Human DHEA sulfation requires direct interaction between PAPS synthase 2 and DHEA sulfotransferase SULT2A1In: The Journal of Biological Chemistry (JBC) Vol. 293 (2018) Nr. 25, pp. 9724 - 9735Online Full Text: dx.doi.org/ (Open Access)
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MTOR inhibitor-based combination therapies for pancreatic cancerIn: British Journal of Cancer (BJC) Vol. 118 (2018) pp. 366 - 377Online Full Text: dx.doi.org/ (Open Access)
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Nanomaterial-microbe cross-talk : physicochemical principles and (patho)biological consequencesIn: Chemical Society Reviews Vol. 47 (2018) Nr. 14, pp. 5312 - 5337Online Full Text: dx.doi.org/
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Nanoparticle binding attenuates the pathobiology of gastric cancer-associated Helicobacter pyloriIn: Nanoscale Vol. 10 (2018) Nr. 3, pp. 1453 - 1463Online Full Text: dx.doi.org/
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Nanoparticle decoration impacts airborne fungal pathobiologyIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 115 (2018) Nr. 27, pp. 7087 - 7092Online Full Text: dx.doi.org/ (Open Access)
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Nanosized food additives impact beneficial and pathogenic bacteria in the human gut : a simulated gastrointestinal studyIn: npj Science of Food Vol. 2 (2018) pp. 22Online Full Text: dx.doi.org/ (Open Access)
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On the influence of substitution patterns in thioether-based luminophores with aggregation-induced emission propertiesIn: ChemistrySelect Vol. 3 (2018) Nr. 4, pp. 985 - 991Online Full Text: dx.doi.org/
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Simultaneous Rayleigh/Mie and Raman/Fluorescence Characterization of Molecularly Functionalized Colloids by Correlative Single-Particle Real-Time Imaging in SuspensionIn: Analytical Chemistry Vol. 90 (2018) Nr. 1, pp. 723 - 728Online Full Text: dx.doi.org/
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Small Meets Smaller : Effects of Nanomaterials on Microbial Biology, Pathology, and EcologyIn: ACS Nano Vol. 12 (2018) Nr. 7, pp. 6351 - 6359Online Full Text: dx.doi.org/
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Survivin antagonizes chemotherapy-induced cell death of colorectal cancer cellsIn: OncoTarget Vol. 9 (2018) Nr. 45, pp. 27835 - 27850Online Full Text: dx.doi.org/ (Open Access)
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TFIIA transcriptional activity is controlled by a 'cleave-And-run' Exportin-1/Taspase 1-switchIn: Journal of Molecular Cell Biology Vol. 10 (2018) Nr. 1, pp. 33 - 47Online Full Text: dx.doi.org/ (Open Access)
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A systematic structure–activity study of a new type of small peptidic transfection vector reveals the importance of a special oxo-anion-binding motif for gene deliveryIn: ChemBioChem Vol. 18 (2017) Nr. 22, pp. 2268 - 2279Online Full Text: dx.doi.org/
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Aromatic thioethers as novel luminophores with aggregation-induced fluorescence and phosphorescenceIn: Chemistry - A European Journal Vol. 23 (2017) Nr. 55, pp. 13660 - 13668Online Full Text: dx.doi.org/
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Efficient Gene Transfection through Inhibition of β-Sheet (Amyloid Fiber) Formation of a Short Amphiphilic Peptide by Gold NanoparticlesIn: Angewandte Chemie International Edition Vol. 56 (2017) Nr. 28, pp. 8083 - 8088Online Full Text: dx.doi.org/
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Morphology-Dependent Cell Imaging by Using a Self-Assembled Diacetylene Peptide AmphiphileIn: Angewandte Chemie International Edition Vol. 56 (2017) Nr. 46, pp. 14526 - 14530Online Full Text: dx.doi.org/
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Site-Specific SERS Assay for Survivin Protein Dimer : From Ensemble Experiments to Correlative Single-Particle ImagingIn: Small Vol. 13 (2017) Nr. 32, pp. 1700802Online Full Text: dx.doi.org/
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Survivin expression pattern in the intestine of normoxic and ischemic ratsIn: BMC Gastroenterology Vol. 17 (2017) pp. 76Online Full Text: dx.doi.org/ (Open Access)
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An Old Flame Never Dies : Survivin in Cancer and Cellular SenescenceIn: Gerontology Vol. 62 (2016) Nr. 2, pp. 173 - 181Online Full Text: dx.doi.org/
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Cleaving for growth : Threonine aspartase 1-a protease relevant for development and diseaseIn: The FASEB Journal Vol. 30 (2016) Nr. 3, pp. 1012 - 1022Online Full Text: dx.doi.org/
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Guanidiniocarbonyl pyrrole (GCP) conjugated PAMAM-G2, a highly efficient vector for gene delivery: The importance of DNA condensationIn: Chemical Communications: ChemComm Vol. 52 (2016) Nr. 84, pp. 12446 - 12449Online Full Text: dx.doi.org/
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Incorporation of a Non-Natural Arginine Analogue into a Cyclic Peptide Leads to Formation of Positively Charged Nanofibers Capable of Gene TransfectionIn: Angewandte Chemie International Edition Vol. 55 (2016) Nr. 2, pp. 598 - 601Online Full Text: dx.doi.org/
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Introduction of a tailor made anion receptor into the side chain of small peptides allows fine-tuning the thermodynamic signature of peptide-DNA bindingIn: Organic and Biomolecular Chemistry Vol. 14 (2016) Nr. 37, pp. 8800 - 8803Online Full Text: dx.doi.org/
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Membrane tethering of APP c-terminal fragments is a prerequisite for T668 phosphorylation preventing nuclear sphere generationIn: Cellular Signalling Vol. 28 (2016) Nr. 11, pp. 1725 - 1734Online Full Text: dx.doi.org/
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RHAMM splice variants confer radiosensitivity in human breast cancer cell linesIn: OncoTarget Vol. 7 (2016) Nr. 16, pp. 21428 - 21440Online Full Text: dx.doi.org/ (Open Access)
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Taspase1 : a 'misunderstood' protease with translational cancer relevanceIn: Oncogene Vol. 35 (2016) Nr. 26, pp. 3351 - 3364Online Full Text: dx.doi.org/
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A Tailor-Made Specific Anion-Binding Motif in the Side Chain Transforms a Tetrapeptide into an Efficient Vector for Gene DeliveryIn: Angewandte Chemie International Edition Vol. 54 (2015) Nr. 10, pp. 2941 - 2944Online Full Text: dx.doi.org/
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Evolutionary divergence of Threonine Aspartase1 leads to species-specific substrate recognitionIn: Biological Chemistry Vol. 396 (2015) Nr. 4, pp. 367 - 376Online Full Text: dx.doi.org/
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Fly versus man : Evolutionary impairment of nucleolar targeting affects the degradome of Drosophila's Taspase1In: The FASEB Journal Vol. 29 (2015) Nr. 5, pp. 1973 - 1985Online Full Text: dx.doi.org/
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No king without a crown – impact of the nanomaterial-protein corona on nanobiomedicineIn: Nanomedicine: Nanotechnology, Biology, and Medicine Vol. 10 (2015) Nr. 3, pp. 503 - 519Online Full Text: dx.doi.org/
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Sumoylation of HDAC2 promotes NF-κB-dependent gene expressionIn: OncoTarget Vol. 6 (2015) Nr. 9, pp. 7123 - 7135Online Full Text: dx.doi.org/ (Open Access)
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The inducible E3 ubiquitin ligases SIAH1 and SIAH2 perform critical roles in breast and prostate cancersIn: Cytokine & Growth Factor Reviews Vol. 26 (2015) Nr. 4, pp. 405 - 413Online Full Text: dx.doi.org/
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The nanoparticle biomolecule corona : lessons learned – challenge accepted?In: Chemical Society Reviews Vol. 44 (2015) Nr. 17, pp. 6094 - 6121Online Full Text: dx.doi.org/ (Open Access)
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miR-542-3p exerts tumor suppressive functions in neuroblastoma by downregulating SurvivinIn: International Journal of Cancer Vol. 136 (2015) Nr. 6, pp. 1308 - 1320Online Full Text: dx.doi.org/ (Open Access)
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Calcium phosphate increases the encapsulation efficiency of hydrophilic drugs (proteins, nucleic acids) into poly(D,L-lactide-co-glycolide acid) nanoparticles for intracellular deliveryIn: Journal of Materials Chemistry B: Materials for Biology and Medicine Vol. 2 (2014) Nr. 41, pp. 7250 - 7259Online Full Text: dx.doi.org/ (Open Access)
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Peptidyl succinimidyl peptides as taspase 1 inhibitorsIn: ChemBioChem Vol. 15 (2014) Nr. 15, pp. 2233 - 2237Online Full Text: dx.doi.org/
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Quantitative profiling of the protein coronas that form around nanoparticlesIn: Nature Protocols Vol. 9 (2014) Nr. 9, pp. 2030 - 2044Online Full Text: dx.doi.org/
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Functional Characterization of Novel Mutations Affecting Survivin (BIRC5)-Mediated Therapy Resistance in Head and Neck Cancer PatientsIn: Human Mutation Vol. 34 (2013) Nr. 2, pp. 395 - 404Online Full Text: dx.doi.org/
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Rapid formation of plasma protein corona critically affects nanoparticle pathophysiologyIn: Nature Nanotechnology Vol. 8 (2013) Nr. 10, pp. 772 - 781Online Full Text: dx.doi.org/
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SIAH proteins : Critical roles in leukemogenesisIn: Leukemia Vol. 27 (2013) Nr. 4, pp. 792 - 802Online Full Text: dx.doi.org/
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Taspase1 : Lizenz zum SchneidenIn: Biospektrum Vol. 19 (2013) Nr. 2, pp. 134 - 136Online Full Text: dx.doi.org/
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Utilizing Combinatorial Chemistry and Rational Design : Peptidic Tweezers with Nanomolar Affinity to DNA Can Be Transformed into Efficient Vectors for Gene Delivery by Addition of a Lipophilic TailIn: Angewandte Chemie International Edition Vol. 52 (2013) Nr. 52, pp. 14016 - 14020Online Full Text: dx.doi.org/
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A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancerIn: OncoTarget Vol. 3 (2012) Nr. 1, pp. 31 - 43Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Allosteric inhibition of Taspase1's pathobiological activity by enforced dimerization in vivoIn: The FASEB Journal Vol. 26 (2012) Nr. 8, pp. 3421 - 3429Online Full Text: dx.doi.org/
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Chemico-genetic strategies to inhibit the leukemic potential of threonine aspartase-1In: Blood Cancer Journal Vol. 2 (2012) Nr. 6, pp. e77Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Differential regulation of PML–RARα stability by the ubiquitin ligases SIAH1/SIAH2 and TRIAD1In: The International Journal of Biochemistry & Cell Biology Vol. 44 (2012) Nr. 1, pp. 132 - 138Online Full Text: dx.doi.org/
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Document Human PAPS synthase isoforms are dynamically regulated enzymes with access to nucleus and cytoplasmIn: PLoS ONE Vol. 7 (2012) Nr. 1, pp. e29559Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Dynamically regulated sumoylation of HDAC2 controls p53 deacetylation and restricts apoptosis following genotoxic stressIn: Journal of Molecular Cell Biology Vol. 4 (2012) Nr. 5, pp. 284 - 293Online Full Text: dx.doi.org/ (Open Access)
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Efficient gene delivery into cells by a surprisingly small three-armed peptide ligandIn: Chemical Science Vol. 3 (2012) Nr. 4, pp. 996 - 1002Online Full Text: dx.doi.org/
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Histone deacetylase inhibitors block IFNγ-induced STAT1 phosphorylationIn: Cellular Signalling Vol. 24 (2012) Nr. 7, pp. 1453 - 1460Online Full Text: dx.doi.org/
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Impact of the nanoparticle-protein corona on colloidal stability and protein structureIn: Langmuir Vol. 28 (2012) Nr. 25, pp. 9673 - 9679Online Full Text: dx.doi.org/
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Overexpression of the Catalytically Impaired Taspase1T234V or Taspase1D233A Variants Does Not Have a Dominant Negative Effect in T(4;11) Leukemia CellsIn: PLoS ONE Vol. 7 (2012) Nr. 5, pp. e34142Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Targeting Taspase1 for Cancer Therapy—LetterIn: Cancer Research Vol. 72 (2012) Nr. 11, pp. 2912Online Full Text: dx.doi.org/
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Bioassays to Monitor Taspase1 Function for the Identification of Pharmacogenetic Inhibitors.In: PLoS ONE Vol. 6 (2011) Nr. 5, pp. e18253Online Full Text: dx.doi.org/ (Open Access)
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Cell-based analysis of structure-function activity of threonine aspartase 1.In: The Journal of Biological Chemistry (JBC) Vol. 286 (2011) Nr. 4, pp. 3007 - 3017Online Full Text: dx.doi.org/
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Nanoparticle size is a critical physicochemical determinant of the human blood plasma corona : a comprehensive quantitative proteomic analysisIn: ACS Nano Vol. 5 (2011) Nr. 9, pp. 7155 - 7167Online Full Text: dx.doi.org/
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The Importin-Alpha/Nucleophosmin Switch Controls Taspase1 Protease Function.In: Traffic: The International Journal of Intracellular Transport Vol. 12 (2011) Nr. 6, pp. 703 - 714Online Full Text: dx.doi.org/
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The heterodimerization domains of MLL-FYRN and FYRC-are potential target structures in t(4;11) leukemia.In: Leukemia Vol. 25 (2011) Nr. 4, pp. 663 - 670Online Full Text: dx.doi.org/
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An otoprotective role for the apoptosis inhibitor protein survivinIn: Cell Death and Disease Vol. 1 (2010) Nr. 51, e51Online Full Text: dx.doi.org/ (Open Access)
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An update on the pathobiological relevance of nuclear receptors for cancers of the head and neckIn: Histology and Histopathology Vol. 25 (2010) Nr. 8, pp. 1093 - 1104Online Full Text: dx.doi.org/
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Cloning and functional characterization of the guinea pig apoptosis inhibitor protein SurvivinIn: Gene Vol. 469 (2010) Nr. 1-2, pp. 9 - 17Online Full Text: dx.doi.org/
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Expression analysis suggests a potential cytoprotective role of Birc5 in the inner earIn: Molecular and Cellular Neuroscience (MCN) Vol. 45 (2010) Nr. 3, pp. 297 - 305Online Full Text: dx.doi.org/
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Nuclear receptors in head and neck cancer: current knowledge and perspectives.In: International Journal of Cancer Vol. 126 (2010) Nr. 4, pp. 801 - 809
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A phosphorylation-acetylation switch regulates STAT1 signaling.In: Genes & development : a journal of cellular and molecular biology Vol. 23 (2009) Nr. 2, pp. 223 - 235
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Inducible NO synthase confers chemoresistance in head and neck cancer by modulating survivinIn: International Journal of Cancer Vol. 124 (2009) Nr. 9, pp. 2033 - 2041
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Prognostic and therapeutic potential of nuclear receptors in head and neck squamous cell carcinomas.In: Journal of Oncology (2009) 349205Online Full Text: dx.doi.org/
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Similar regulation of human inducible nitric oxide synthase (iNOS) expression by different isoforms of the RNA binding protein AUF1In: The Journal of Biological Chemistry (JBC) Vol. 284 (2009) Nr. 5, pp. 2755 - 2766
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Translocation biosensors – cellular system integrators to dissect CRM1-dependent nuclear export by chemicogenomics.In: Sensors Vol. 9 (2009) Nr. 7, pp. 5423 - 5445Online Full Text: dx.doi.org/ (Open Access)
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Histone deacetylase inhibitors and hydroxyurea modulate the cell cycle and cooperatively induce apoptosis.In: Oncogene : an international journal Vol. 27 (2008) Nr. 6, pp. 732 - 740
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NO signaling confers cytoprotectivity through the survivin network in ovarian carcinomasIn: Cancer Research Vol. 68 (2008) Nr. 13, pp. 5159 - 5166
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Phosphorylation of nm23-H1 by CKI induces its complex formation with h-prune and promotes cell motilityIn: Oncogene Vol. 27 (2008) Nr. 13, pp. 1853 - 1864Online Full Text: dx.doi.org/
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Therapeutic potential of nuclear receptors.In: Expert Opinion on Therapeutic Patents Vol. 18 (2008) Nr. 8, pp. 861 - 888
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Dynamic Intracellular Survivin as an Early Prognostic Marker in Oral Squamous Cell Carcinomas : Underlying Molecular Mechanism and PotentialIn: The Journal of Pathology Vol. 211 (2007) Nr. 5, pp. 532 - 540
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Dynamic survivin in head and neck cancer: Molecular mechanism and therapeutic potentialIn: International Journal of Cancer Vol. 121 (2007) Nr. 6, pp. 1169 - 1174
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Nuclear and Cytoplasmic Survivin: Molecular Mechanism, Prognostic, and Therapeutic Potential.In: Cancer Research Vol. 67 (2007) Nr. 13, pp. 5999 - 6002
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Nuclear export is essential for the tumor-promoting activity of survivinIn: The FASEB Journal: the official journal of the Federation of American Societies for Experimental Biology / Experimental Biology ; Transforming the future through science ; Chicago, April 22-26, 2017 Vol. 21 (2007) Nr. 1, pp. 207 - 216
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Survivin's Dual Role - An Export's View.In: Cell Cycle Vol. 6 (2007) Nr. 5, pp. 518 - 521
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The Role of Survivin for Radiation Therapy : Prognostic and Predictive Factor and Therapeutic TargetIn: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Vol. 183 (2007) Nr. 11, pp. 593 - 599Online Full Text: dx.doi.org/
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The differentiation antigen NY-BR-1 is a potential target for antibody based therapies in breast cancer.In: International Journal of Cancer Vol. 120 (2007) Nr. 12, pp. 2635 - 2642
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The survivin splice variant survivin-3B is cytoprotective and can function as a chromosomal passenger complex proteinIn: Cell Cycle Vol. 6 (2007) Nr. 12, pp. 1502 - 1509Online Full Text: dx.doi.org/
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Acetylation of Stat1 modulates NF-kB activityIn: Genes & development : a journal of cellular and molecular biology Vol. 20 (2006) Nr. 4, pp. 473 - 485
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Nucleocytoplasmic shuttling and the biological activity of mouse survivin are regulated by an active nuclear export signalIn: Traffic: The International Journal of Intracellular Transport Vol. 7 (2006) Nr. 11, pp. 1461 - 1472Online Full Text: dx.doi.org/
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Targeted induction of apoptosis by chimeric granzyme B fusion proteins carrying antibody and growth factor domains for cell recognition.In: Cell death & differentiation : D & D ; cdd Vol. 13 (2006) Nr. 4, pp. 576 - 585
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The Survivin-Crm1 interaction is essential for chromosomal passenger complex localization and function.In: EMBO Reports Vol. 7 (2006) Nr. 12, pp. 1259 - 1265
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Development of an autofluorescent translocation biosensor system to investigate protein-protein interactions in living cellsIn: Analytical Chemistry Vol. 77 (2005) Nr. 15, pp. 4815 - 4820Online Full Text: dx.doi.org/
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Nuclear Export Is Evolutionarily Conserved in CVC Paired-Like Homeobox Proteins and Influences Protein Stability, Transcriptional Activation, and Extracellular Secretion.In: Molecular and Cellular Biology (MCB) Vol. 6 (2005) Nr. 7, pp. 594 - 606
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Translocation Biosensors to Study Signal-Specific Nucleo-Cytoplasmic Transport, Protease Activity and Protein–Protein InteractionsIn: Traffic: The International Journal of Intracellular Transport Vol. 6 (2005) Nr. 7, pp. 594 - 606
Journal articles
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Translocation Biosensors—Versatile Tools to Probe Protein Functions in Living CellsIn: High Content Screening 2018, pp. 195 - 210Online Full Text: dx.doi.org/
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Analysis of HDACi-induced changes in chromosomal passenger complex localizationIn: HDAC/HAT Function Assessment and Inhibitor Development: Methods and Protocols / Krämer, Oliver H. (Eds.) 2017, pp. 47 - 59Online Full Text: dx.doi.org/
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Bio-Nano InteractionsIn: Adverse effects of engineered nanomaterials: exposure, toxicology, and impact on human health / Fadeel, Bengt; Pietroiusti, Antonio; Shvedova, Anna (Eds.) 2017, pp. 1 - 12Online Full Text: dx.doi.org/
Book articles / Proceedings papers
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