Publications 2024
https://pubmed.ncbi.nlm.nih.gov/39344516/
Delayed DNase-I Administration but Not Gasdermin-D Inhibition Induces Hemorrhagic Transformation After Transient Focal Cerebral Ischemia in Mice
Stroke
2024-11-06
55(11):e297-e299. doi: 10.1161/STROKEAHA.124.047862. Epub 2024 Sep 30
https://www.ahajournals.org/doi/10.1161/STROKEAHA.124.047862?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
Yin D, Wang C, Singh V, Tuz AA, Doeppner TR, Gunzer M, Hermann DM.
https://pubmed.ncbi.nlm.nih.gov/39395581/
Proteomic Characterization of 1000 Human and Murine Neutrophils Freshly Isolated From Blood and Sites of Sterile Inflammation
Mol Cell Proteomics
2024-10-11
23(11):100858. doi: 10.1016/j.mcpro.2024.100858
https://www.sciencedirect.com/science/article/pii/S1535947624001488?via%3Dihub
Ghosh S, Tuz AA, Stenzel M, Singh V, Richter M, Soehnlein O, Lange E, Heyer R, Cibir Z, Beer A, Jung M, Nagel D, Hermann DM, Hasenberg A, Grüneboom A, Sickmann A, Gunzer M.
https://pubmed.ncbi.nlm.nih.gov/39315830/
Stroke of Consistency: Streamlining Multicenter Protocols for Enhanced Reproducibility of Infarct Volumes in Preclinical Stroke Research
Stroke
2024-10-09
55(10):2522-2527. doi: 10.1161/STROKEAHA.124.047232. Epub 2024 Sep 24.
https://www.ahajournals.org/doi/10.1161/STROKEAHA.124.047232?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
Llovera G, Langhauser F, Isla Cainzos S, Hoppen M, Abberger H, Mohamud Yusuf A, Mencl S, Heindl S, Ricci A, Haupeltshofer S, Kuchenbecker-Pöls L, Gunzer M, Hansen W, Hermann DM, Gelderblom M, Schmidt-Pogoda A, Minnerup J, Kleinschnitz C, Magnus T, Liesz A.
https://pubmed.ncbi.nlm.nih.gov/39113408/
Arterial specification precedes microvascular restitution in the peri-infarct cortex that is driven by small microvessels.
J Cereb Blood Flow Metab
2024-08-07
271678X241270407. doi: 10.1177/0271678X241270407.
https://journals.sagepub.com/doi/full/10.1177/0271678X241270407?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org
Hagemann N, Qi Y, Mohamud Yusuf A, Li A, Zhang X, Spangenberg P, Squire A, Doeppner TR, Jin F, Zhao S, Chen J, Mosig A, Gunzer M, Hermann DM.
https://pubmed.ncbi.nlm.nih.gov/39085419/
Cranioencephalic functional lymphoid units in glioblastoma.
Nat Med.
2024-07-31
doi: 10.1038/s41591-024-03152-x
https://www.nature.com/articles/s41591-024-03152-x
Dobersalske C, Rauschenbach L, Hua Y, Berliner C, Steinbach A, Grüneboom A, Kokkaliaris KD, Heiland DH, Berger P, Langer S, Tan CL, Stenzel M, Landolsi S, Weber F, Darkwah Oppong M, Werner RA, Gull H, Schröder T, Linsenmann T, Buck AK, Gunzer M, Stuschke M, Keyvani K, Forsting M, Glas M, Kipnis J, Steindler DA, Reinhardt HC, Green EW, Platten M, Tasdogan A, Herrmann K, Rambow F, Cima I, Sure U, Scheffler B.
https://pubmed.ncbi.nlm.nih.gov/38862851/
Multisensory Extended Reality Applications Offer Benefits for Volumetric Biomedical Image Analysis in Research and Medicine.
J Imaging Inform Med.
2024-06-11
doi: 10.1007/s10278-024-01094-x.
Krieger K, Egger J, Kleesiek J, Gunzer M, Chen J.
https://pubmed.ncbi.nlm.nih.gov/39195931/
Stroke and myocardial infarction induce neutrophil extracellular trap release disrupting lymphoid organ structure and immunoglobulin secretion
Nat Cardiovasc Res.
2024-05-03
doi: 10.1038/s44161-024-00462-8.
Tuz AA, Ghosh S, Karsch L, Ttoouli D, Sata SP, Ulusoy Ö, Kraus A, Hoerenbaum N, Wolf JN, Lohmann S, Zwirnlein F, Kaygusuz V, Lakovic V, Tummes HL, Beer A, Gallert M, Thiebes S, Qefalia A, Cibir Z, Antler M, Korste S, Haj Yehia E, Michel L, Rassaf T, Kaltwasser B, Abdelrahman H, Mohamud Yusuf A, Wang C, Yin D, Haeusler L, Lueong S, Richter M, Engel DR, Stenzel M, Soehnlein O, Frank B, Solo-Nomenjanahary M, Ho-Tin-Noé B, Siveke JT, Totzeck M, Hoffmann D, Grüneboom A, Hagemann N, Hasenberg A, Desilles JP, Mazighi M, Sickmann A, Chen J, Hermann DM, Gunzer M, Singh V.
https://pubmed.ncbi.nlm.nih.gov/?term=Matthias+Gunzer&filter=years.2024-2024&sort=pubdate
PD-1 knockout on cytotoxic primary murine CD8+ T cells improves their motility in retrovirus infected mice
Front Immunol.
2024-04-29
10.3389/fimmu.2024.1338218. eCollection 2024
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1338218/full
Mittermüller D, Otto L, Kilian AL, Schnormeier AK, Littwitz-Salomon E, Hasenberg A, Dittmer U, Gunzer M.
https://pubmed.ncbi.nlm.nih.gov/38387309/
Neutrophils are indispensable for adverse cardiac remodeling in heart failure
J Mol Cell Cardiol
2024-04-26
189:1-11. doi: 10.1016/j.yjmcc.2024.02.005. Epub 2024 Feb 22.
Antipenko S, Mayfield N, Jinno M, Gunzer M, Ismahil MA, Hamid T, Prabhu SD, Rokosh G.
https://pubmed.ncbi.nlm.nih.gov/38357819/
Microvascular Network Remodeling in the Ischemic Mouse Brain Defined by Light Sheet Microscopy
Arterioscler Thromb Vasc Biol.
2024-04-25
44(4):915-929. doi: 10.1161/ATVBAHA.123.320339.
https://www.ahajournals.org/doi/10.1161/ATVBAHA.123.320339?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
Hagemann N, Qi Y, Mohamud Yusuf A, Li A, Squire A, Tertel T, Giebel B, Ludewig P, Spangenberg P, Chen J, Mosig A, Gunzer M, Hermann DM.
https://pubmed.ncbi.nlm.nih.gov/38396254/
ComplexEye: a multi-lens array microscope for high-throughput cell migration analysis.
Nat Rev Immunol.
2024-04-24
24(4):233. doi: 10.1038/s41577-024-01009-5.
https://www.nature.com/articles/s41577-024-01009-5
Zülal Cibir, Matthias Gunzer
https://www.uni-due.de/2024-04-23-immunodeficiency-after-a-heart-attack-or-stroke
Stroke and myocardial infarction induce neutrophil extracellular trap release disrupting lymphoid organ structure and immunoglobulin secretion
Nat.Cardiovasc. Res.
2024-04-23
https://www.nature.com/articles/s44161-024-00462-8
Ali A. Tuz, Susmita Ghosh, Laura Karsch, Dimitris Ttoouli, Sai P. Sata, Özgür Ulusoy, Andreas Kraus, Nils Hoerenbaum, Jan-Niklas Wolf, Sabrina Lohmann, Franziska Zwirnlein, Viola Kaygusuz, Vivian Lakovic, Hannah-Lea Tummes, Alexander Beer, Markus Gallert, Stephanie Thiebes, Altea Qefalia, Zülal Cibir, Medina Antler, Sebastian Korste, Elias Haj Yehia, Lars Michel, Tienush Rassaf, Britta Kaltwasser, Hossam Abdelrahman, Ayan Mohamud Yusuf, Chen Wang, Dongpei Yin, Lars Haeusler, Smiths Lueong, Mathis Richter, Daniel R. Engel, Martin Stenzel, Oliver Soehnlein, Benedikt Frank, Mialitiana Solo-Nomenjanahary, Benoît Ho-Tin-Noé, Jens T. Siveke, Matthias Totzeck, Daniel Hoffmann, Anika Grüneboom, Nina Hagemann, Anja Hasenberg, Jean-Philippe Desilles, Mikael Mazighi, Albert Sickmann, Jianxu Chen, Dirk M. Hermann,Matthias Gunzer & Vikramjeet Singh
https://pubmed.ncbi.nlm.nih.gov/38301333/
In-vivo tracking of deuterium metabolism in mouse organs using LC-MS/MS
J Chromatogr A
2024-01-28
1717:464691. doi: 10.1016j.chroma.2024.464691.
Kasarla SS, Flocke V, Saw NMT, Fecke A, Sickmann A,Gunzer M, Flögel U, Phapale P.
Delayed DNase-I Administration but Not Gasdermin-D Inhibition Induces Hemorrhagic Transformation After Transient Focal Cerebral Ischemia in Mice
Stroke
2024-11-06
55(11):e297-e299. doi: 10.1161/STROKEAHA.124.047862. Epub 2024 Sep 30
https://www.ahajournals.org/doi/10.1161/STROKEAHA.124.047862?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
Yin D, Wang C, Singh V, Tuz AA, Doeppner TR, Gunzer M, Hermann DM.
https://pubmed.ncbi.nlm.nih.gov/39395581/
Proteomic Characterization of 1000 Human and Murine Neutrophils Freshly Isolated From Blood and Sites of Sterile Inflammation
Mol Cell Proteomics
2024-10-11
23(11):100858. doi: 10.1016/j.mcpro.2024.100858
https://www.sciencedirect.com/science/article/pii/S1535947624001488?via%3Dihub
Ghosh S, Tuz AA, Stenzel M, Singh V, Richter M, Soehnlein O, Lange E, Heyer R, Cibir Z, Beer A, Jung M, Nagel D, Hermann DM, Hasenberg A, Grüneboom A, Sickmann A, Gunzer M.
https://pubmed.ncbi.nlm.nih.gov/39315830/
Stroke of Consistency: Streamlining Multicenter Protocols for Enhanced Reproducibility of Infarct Volumes in Preclinical Stroke Research
Stroke
2024-10-09
55(10):2522-2527. doi: 10.1161/STROKEAHA.124.047232. Epub 2024 Sep 24.
https://www.ahajournals.org/doi/10.1161/STROKEAHA.124.047232?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
Llovera G, Langhauser F, Isla Cainzos S, Hoppen M, Abberger H, Mohamud Yusuf A, Mencl S, Heindl S, Ricci A, Haupeltshofer S, Kuchenbecker-Pöls L, Gunzer M, Hansen W, Hermann DM, Gelderblom M, Schmidt-Pogoda A, Minnerup J, Kleinschnitz C, Magnus T, Liesz A.
https://pubmed.ncbi.nlm.nih.gov/39113408/
Arterial specification precedes microvascular restitution in the peri-infarct cortex that is driven by small microvessels.
J Cereb Blood Flow Metab
2024-08-07
271678X241270407. doi: 10.1177/0271678X241270407.
https://journals.sagepub.com/doi/full/10.1177/0271678X241270407?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org
Hagemann N, Qi Y, Mohamud Yusuf A, Li A, Zhang X, Spangenberg P, Squire A, Doeppner TR, Jin F, Zhao S, Chen J, Mosig A, Gunzer M, Hermann DM.
https://pubmed.ncbi.nlm.nih.gov/39085419/
Cranioencephalic functional lymphoid units in glioblastoma.
Nat Med.
2024-07-31
doi: 10.1038/s41591-024-03152-x
https://www.nature.com/articles/s41591-024-03152-x
Dobersalske C, Rauschenbach L, Hua Y, Berliner C, Steinbach A, Grüneboom A, Kokkaliaris KD, Heiland DH, Berger P, Langer S, Tan CL, Stenzel M, Landolsi S, Weber F, Darkwah Oppong M, Werner RA, Gull H, Schröder T, Linsenmann T, Buck AK, Gunzer M, Stuschke M, Keyvani K, Forsting M, Glas M, Kipnis J, Steindler DA, Reinhardt HC, Green EW, Platten M, Tasdogan A, Herrmann K, Rambow F, Cima I, Sure U, Scheffler B.
https://pubmed.ncbi.nlm.nih.gov/38862851/
Multisensory Extended Reality Applications Offer Benefits for Volumetric Biomedical Image Analysis in Research and Medicine.
J Imaging Inform Med.
2024-06-11
doi: 10.1007/s10278-024-01094-x.
Krieger K, Egger J, Kleesiek J, Gunzer M, Chen J.
https://pubmed.ncbi.nlm.nih.gov/39195931/
Stroke and myocardial infarction induce neutrophil extracellular trap release disrupting lymphoid organ structure and immunoglobulin secretion
Nat Cardiovasc Res.
2024-05-03
doi: 10.1038/s44161-024-00462-8.
Tuz AA, Ghosh S, Karsch L, Ttoouli D, Sata SP, Ulusoy Ö, Kraus A, Hoerenbaum N, Wolf JN, Lohmann S, Zwirnlein F, Kaygusuz V, Lakovic V, Tummes HL, Beer A, Gallert M, Thiebes S, Qefalia A, Cibir Z, Antler M, Korste S, Haj Yehia E, Michel L, Rassaf T, Kaltwasser B, Abdelrahman H, Mohamud Yusuf A, Wang C, Yin D, Haeusler L, Lueong S, Richter M, Engel DR, Stenzel M, Soehnlein O, Frank B, Solo-Nomenjanahary M, Ho-Tin-Noé B, Siveke JT, Totzeck M, Hoffmann D, Grüneboom A, Hagemann N, Hasenberg A, Desilles JP, Mazighi M, Sickmann A, Chen J, Hermann DM, Gunzer M, Singh V.
https://pubmed.ncbi.nlm.nih.gov/?term=Matthias+Gunzer&filter=years.2024-2024&sort=pubdate
PD-1 knockout on cytotoxic primary murine CD8+ T cells improves their motility in retrovirus infected mice
Front Immunol.
2024-04-29
10.3389/fimmu.2024.1338218. eCollection 2024
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1338218/full
Mittermüller D, Otto L, Kilian AL, Schnormeier AK, Littwitz-Salomon E, Hasenberg A, Dittmer U, Gunzer M.
https://pubmed.ncbi.nlm.nih.gov/38387309/
Neutrophils are indispensable for adverse cardiac remodeling in heart failure
J Mol Cell Cardiol
2024-04-26
189:1-11. doi: 10.1016/j.yjmcc.2024.02.005. Epub 2024 Feb 22.
Antipenko S, Mayfield N, Jinno M, Gunzer M, Ismahil MA, Hamid T, Prabhu SD, Rokosh G.
https://pubmed.ncbi.nlm.nih.gov/38357819/
Microvascular Network Remodeling in the Ischemic Mouse Brain Defined by Light Sheet Microscopy
Arterioscler Thromb Vasc Biol.
2024-04-25
44(4):915-929. doi: 10.1161/ATVBAHA.123.320339.
https://www.ahajournals.org/doi/10.1161/ATVBAHA.123.320339?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
Hagemann N, Qi Y, Mohamud Yusuf A, Li A, Squire A, Tertel T, Giebel B, Ludewig P, Spangenberg P, Chen J, Mosig A, Gunzer M, Hermann DM.
https://pubmed.ncbi.nlm.nih.gov/38396254/
ComplexEye: a multi-lens array microscope for high-throughput cell migration analysis.
Nat Rev Immunol.
2024-04-24
24(4):233. doi: 10.1038/s41577-024-01009-5.
https://www.nature.com/articles/s41577-024-01009-5
Zülal Cibir, Matthias Gunzer
https://www.uni-due.de/2024-04-23-immunodeficiency-after-a-heart-attack-or-stroke
Stroke and myocardial infarction induce neutrophil extracellular trap release disrupting lymphoid organ structure and immunoglobulin secretion
Nat.Cardiovasc. Res.
2024-04-23
https://www.nature.com/articles/s44161-024-00462-8
Ali A. Tuz, Susmita Ghosh, Laura Karsch, Dimitris Ttoouli, Sai P. Sata, Özgür Ulusoy, Andreas Kraus, Nils Hoerenbaum, Jan-Niklas Wolf, Sabrina Lohmann, Franziska Zwirnlein, Viola Kaygusuz, Vivian Lakovic, Hannah-Lea Tummes, Alexander Beer, Markus Gallert, Stephanie Thiebes, Altea Qefalia, Zülal Cibir, Medina Antler, Sebastian Korste, Elias Haj Yehia, Lars Michel, Tienush Rassaf, Britta Kaltwasser, Hossam Abdelrahman, Ayan Mohamud Yusuf, Chen Wang, Dongpei Yin, Lars Haeusler, Smiths Lueong, Mathis Richter, Daniel R. Engel, Martin Stenzel, Oliver Soehnlein, Benedikt Frank, Mialitiana Solo-Nomenjanahary, Benoît Ho-Tin-Noé, Jens T. Siveke, Matthias Totzeck, Daniel Hoffmann, Anika Grüneboom, Nina Hagemann, Anja Hasenberg, Jean-Philippe Desilles, Mikael Mazighi, Albert Sickmann, Jianxu Chen, Dirk M. Hermann,Matthias Gunzer & Vikramjeet Singh
https://pubmed.ncbi.nlm.nih.gov/38301333/
In-vivo tracking of deuterium metabolism in mouse organs using LC-MS/MS
J Chromatogr A
2024-01-28
1717:464691. doi: 10.1016j.chroma.2024.464691.
Kasarla SS, Flocke V, Saw NMT, Fecke A, Sickmann A,Gunzer M, Flögel U, Phapale P.