The Department Gunzer is focused on disease models of fungal and bacterial lung infection as well as sterile inflammation during stroke or tumor growth.

We investigate the function of immune cells in the context of an intact animal organism. We employe advanced methods of optical imaging and innovative experimental systems, and analyze how defined populations of immune cells behave under physiological and pathological conditions.

The underlying molecular mechanisms are elucidated.

More details on you can read in the projects of the AG Gunzer.

The IMaging Center ESsen (IMCES) is the core facility for microscopy of the Institute for Experimental Immunology and Imaging at the Faculty of Medicine, Universitätsklinikum Essen and Universität Duisburg-Essen.

The facility brings together state-of-the-art equipment and expertise in light and electron microscopy, in vivo and intravital imaging, and image analysis. The IMCES laboratories and microscopy rooms have permission for working at the S1 and S2 biological safety level.

More details on you can read here.

The Department Immunodynamics investigates immunological mechanisms that underlie diseases such as persistent infections and cancer. State of the art approaches are used, such as imaging mass spectrometry, bioinformatics and microscopy to understand the mechanisms that spatially regulate leukocyte migration and function. We develop interdisciplinary co-registration algorithms that combine multimodal imaging approaches, such as immunohistochemistry (IHC), matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) and liquid chromatography with tandem mass spectrometry (LC-MS/MS). Our overall aim is to decode immunological landscapes to develop novel therapeutic approaches to treat diseases.

More details on you can read here.