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Principal Investigators
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Titles of research projects
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L
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Role of molecular heterogeneity of NSCLC in RT outcome
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L1
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Grüner
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Role of molecular heterogeneity for radiation resistance and metastatic ability in NSCLC
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L2
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Matschke
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Subtype-specific vulnerabilities of KRAS-driven NSCLC cells with intrinsic or adaptive radiation resistance
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L3
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Schramm
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Impact of somatic Lamin mutations on radiation response in lung cancer
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L4
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Stuschke
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Interplay of exosomal miRNAs and genomic alteration in radiation response modulation and use as prognostic factors in NSCLC
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P
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Role of spatial heterogeneity of PDAC in RT outcome
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P1
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Siveke/Matschke/Timmermann
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Effect of KRAS gene dosage and molecular subtype on radiosensitivity in PDAC
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P2
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Siveke
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Radiotherapy-induced tumor and stromal cell state regulation in PDAC
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P3
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Lückerath
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Exploring radioimmunotherapy (RIT) as an immunomodulatory therapy in quasi-mesenchymal (QM) versus classic PDAC
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T
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Role of host-specific immune repertoires in RT-induced toxicity
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T1
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Guberina/Jendrossek
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Biomarkers of pneumonitis and lung fibrosis upon thoracic RT/RCTx with or without concomitant anti-PD-L1 antibody therapy
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T2
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Jendrossek/Westendorf
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Role of the host microbiota for radiation-induced lung toxicity
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T3
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Rassaf
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Modulation of stroma-immune interaction to prevent RT-induced cardiac injury
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M
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Computational Modeling
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M1
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Hoffmann
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Development of modular computational modeling pipelines for reproducible radiation oncology research
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M2
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Farahpour
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Mathematical modeling of radiotherapy-induced immune responses
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