AG Melanie Fiedler

Virusinfektionen unter Immunsuppression

Forschungsschwerpunkte

  • Hepatitis E-Virusinfektion bei Immunsuppression
  • Immunität gegen Masern, Mumps und Röteln

Projekt

Bei Patienten mit immunsuppressiver Therapie verläuft die Hepatitis E-Virus (HEV)-Infektion häufig chronisch. In Zusammenarbeit mit der Klinik für Nephrologie untersuchen wir die Häufigkeit der HEV-Infektion bei Patienten nach Nierentransplantation und den Erfolg einer frühen Ribavirintherapie. In Kooperation mit dem Konsiliarlabor für HEV, Institut für Klinische Mikrobiologie und Hygiene, Universitätsklinikum Regensburg, werden Sequenzanalysen durchgeführt.

Die Bestimmung der Immunität gegen Masern, Mumps und Röteln (MMR) ist wichtig bei Kindern nach Nierentransplantation und unter Immunsuppression. Die chronische Erkrankung dieser Kinder vor Transplantation kann zu einem schlechteren Ansprechen auf die Impfungen gegen diese Erreger führen. Die Immunität wird in der Regel mit IgG-Testungen überprüft, die allerdings nur eine begrenzte Aussagekraft zur Immunitätslage haben. Wir überprüfen die Funktionalität der Antikörper mittels Plaqueassays/Neutralisationstesten in Zusammenarbeit mit dem Nationalen Referenzzentrum für MMR und vergleichen die Aussagekraft verschiedener Teste miteinander.

Arbeitsgruppe

Dr. med. Melanie Fiedler
Tel.: +49 (0)201 723 85457
E-Mail: melanie.fiedler@uni-due.de

Publikationen

    2023

    Artikel in Zeitschriften

  • Lodde, Georg; Krefting, Frederik; Placke, Jan-Malte; Schneider, Lea; Fiedler, Melanie; Dittmer, Ulf; Becker, Jürgen; Hölsken, Stefanie; Schadendorf, Dirk; Ugurel, Selma; Sondermann, Wiebke
    COVID-19 vaccination in psoriasis patients receiving systemic treatment : A prospective single-center study
    In: Frontiers in Immunology Jg. 14 (2023) S. 1107438
    Online Volltext: dx.doi.org/ (Open Access)

    • 2022

    Artikel in Zeitschriften

  • Lodde, Georg; Fiedler, Melanie; Dittmer, Ulf; Placke, Jan-Malte; Jansen, Philipp; Becker, Jürgen; Zimmer, Lisa; Livingstone, Elisabeth; Schadendorf, Dirk; Sondermann, Wiebke; Ugurel, Selma
    COVID-19 vaccination in advanced skin cancer patients receiving systemic anticancer treatment : A prospective singlecenter study investigating seroconversion rates
    In: Frontiers in Oncology Jg. 12 (2022) 879876
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Dehnen, Dorothea; Dehnen, Katja; Trilling, Mirko; Fiedler, Melanie; Drexler, Julia; Goralski, Marcel; Le-Trilling, Vu Thuy Khanh; Schöler, Lara; Jöckel, Karl-Heinz; Heßbrügge, Martina
    Discrepancy between frequent occurrence of COVID-19-like symptoms and low seroconversion rates among healthcare workers
    In: Journal of Medical Virology Jg. 94 (2022) Nr. 3: Special Issue on New coronavirus (2019‐nCoV or SARS‐CoV‐2) and the outbreak of the respiratory illness (COVID‐19): Part‐XVIII, S. 951 - 957
    Online Volltext: dx.doi.org/ (Open Access)
  • Schöler, Lara; Le-Trilling, Vu Thuy Khanh; Dittmer, Ulf; Fiedler, Melanie; Trilling, Mirko
    Establishment and clinical validation of an in-cell-ELISA-based assay for the rapid quantification of Rabies virus neutralizing antibodies
    In: PLoS Neglected Tropical Diseases Jg. 16 (2022) Nr. 5, e0010425
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Holtkamp, Caroline; Fiedler, Melanie; Dittmer, Ulf; Anastasiou, Olympia E.
    The Course of Anti-HBc Antibodies over Time in Immunocompromised Hosts
    In: Vaccines Jg. 10 (2022) Nr. 2, 137
    Online Volltext: dx.doi.org/ (Open Access)

    • 2021

    Artikel in Zeitschriften

  • Anastasiou, Olympia E.; Theodoropoulos, Fotis; Taube, Christian; Fiedler, Melanie; Dittmer, Ulf
    Common respiratory viral infections : Bilateral versus unilateral bronchoalveolar lavage versus endotracheal aspiration
    In: Journal of Medical Virology Jg. 93 (2021) Nr. 6, S. 3955 - 3959
    Online Volltext: dx.doi.org/
  • Gliga, Smaranda; Fiedler, Melanie; Dornieden, Theresa; Achterfeld, Anne; Paul, Andreas; Horn, Peter; Herzer, Kerstin; Lindemann, Monika
    Comparison of three cellular assays to predict the course of CMV infection in liver transplant recipients
    In: Vaccines Jg. 9 (2021) Nr. 2, S. 88
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Gäckler, Anja; Struve, Christoph; Mülling, Nils; Eisenberger, Ute; Korth, Johannes; Babel, Nina; Kribben, Andreas; Fiedler, Melanie; Witzke, Oliver; Rohn, Hana
    Norovirus Infections in Kidney Transplant Recipients
    In: Transplantation Jg. 105 (2021) Nr. 12, S. 2655 - 2660
    Online Volltext: dx.doi.org/
  • Fleischer, Michael; Köhrmann, Martin; Dolff, Sebastian; Szepanowski, Fabian; Schmidt, Karsten; Herbstreit, Frank; Güngör, Cansu; Stolte, Benjamin; Steiner, Katharina Marie; Stadtler, Christine; Riße, Joachim; Fiedler, Melanie; Meyer zu Hörste, Gerd; Mausberg, Anne-K.; Kill, Clemens; Forsting, Michael; Sure, Ulrich; Dittmer, Ulf; Witzke, Oliver; Brenner, Thorsten; Kleinschnitz, Christoph; Stettner, Mark
    Observational cohort study of neurological involvement among patients with SARS-CoV-2 infection
    In: Therapeutic Advances in Neurological Disorders Jg. 14 (2021)
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Fiedler, Melanie; Holtkamp, Caroline; Dittmer, Ulf; Anastasiou, Olympia E.
    Performance of the LIAISON® SARS-CoV-2 Antigen Assay vs. SARS-CoV-2-RT-PCR
    In: Pathogens Jg. 10 (2021) Nr. 6, 658
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Dietrich, Maximilian; Märtens, M.; von der Forst, M.; Bruckner, T.; Uhle, F.; Fiedler, Melanie; Weiterer, S.; Hackert, T.; Brenner, Thorsten; Weigand, M.A.
    Vitamin C und Thiamin im Septischen Schock – Eine retrospektive Vorher-Nachher-Studie an chirurgischen Patienten
    In: Anästhesiologie & Intensivmedizin Jg. 62 (2021) Nr. 2, S. 63 - 69
    Online Volltext: dx.doi.org/

    • 2019

    Artikel in Zeitschriften

  • Friebus-Kardash, Justa; Eisenberger, Ute; Ackermann, Jessica; Kribben, Andreas; Witzke, Oliver; Wenzel, Jürgen; Rohn, Hana; Fiedler, Melanie
    Prevalence of active hepatitis E virus infection and efficacy of ribavirin treatment in renal allograft recipients
    In: Transplant Infectious Disease Jg. 21 (2019) Nr. 3, e13088
    Online Volltext: dx.doi.org/

    • 2018

    Artikel in Zeitschriften

  • Lindemann, Monika; Eiz-Vesper, Britta; Steckel, Nina Kristin; Tischer, Sabine; Fiedler, Melanie; Heinold, Andreas; Klisanin, Vesna; Maecker-Kolhoff, Britta; Blasczyk, Rainer; Horn, Peter; Beelen, Dietrich; Koldehoff, Michael
    Adoptive transfer of cellular immunity against cytomegalovirus by virus-specific lymphocytes from a third-party family donor
    In: Bone Marrow Transplantation Jg. 53 (2018) Nr. 10, S. 1351 - 1355
    Online Volltext: dx.doi.org/ (Open Access)
  • Karimzadeh, Hadi; Kiraithe, Muthamia M.; Kosinska, Anna D.; Glaser, Manuel; Fiedler, Melanie; Oberhardt, Valerie; Alizei, Elahe Salimi; Hofmann, Maike; Mok, Juk Yee; Nguyen, Melanie; van Esch, Wim J.E.; Budeus, Bettina; Grabowski, Jan; Homs, Maria; Olivero, Antonella; Keyvani, Hossein; Rodríguez-Frías, Francisco; Tabernero, David; Buti, Maria; Heinold, Andreas; Alavian, Seyed Moayed; Bauer, Tanja; Wiesch, Julian Schulze zur; Raziorrouh, Bijan; Hoffmann, Daniel; Smedile, Antonina; Rizzetto, Mario; Wedemeyer, Heiner; Timm, Jörg; Antes, Iris; Neumann-Haefelin, Christoph; Protzer, Ulrike; Roggendorf, Michael
    Amino acid substitutions within HLA-B*27- restricted T cell epitopes prevent recognition by hepatitis delta virus-specific CD8⁺ T cells
    In: Journal of Virology Jg. 92 (2018) Nr. 13, e01891-17
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Krawczyk, Adalbert; Ackermann, Jessica; Goitowski, Birgit; Trenschel, Rudolf; Ditschkowski, Markus; Timm, Jörg; Ottinger, Hellmut; Beelen, Dietrich; Grüner, Nico; Fiedler, Melanie
    Assessing the risk of CMV reactivation and reconstitution of antiviral immune response post bone marrow transplantation by the QuantiFERON-CMV-assay and real time PCR
    In: Journal of Clinical Virology Jg. 99-100 (2018) S. 61 - 66
    Online Volltext: dx.doi.org/ (Open Access)
  • Wohlfarth, Philipp; Turki, Amin T.; Steinmann, Jörg; Fiedler, Melanie; Steckel, Nina Kristin; Beelen, Dietrich; Liebregts, Tobias
    Microbiologic Diagnostic Workup of Acute Respiratory Failure with Pulmonary Infiltrates after Allogeneic Hematopoietic Stem Cell Transplantation : Findings in the Era of Molecular- and Biomarker-Based Assays
    In: Biology of Blood and Marrow Transplantation Jg. 24 (2018) Nr. 8, S. 1707 - 1714
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Gliga, Smaranda; Korth, Johannes; Krawczyk, Adalbert; Wilde, Benjamin; Horn, Peter; Witzke, Oliver; Lindemann, Monika; Fiedler, Melanie
    T-Track-CMV and QuantiFERON-CMV assays for prediction of protection from CMV reactivation in kidney transplant recipients
    In: Journal of Clinical Virology Jg. 105 (2018) S. 91 - 96
    Online Volltext: dx.doi.org/

    • Abstracts

  • Turki, Amin T.; Tsachakis-Mück, Nikolaos; Leserer, Saskia; Yi, Ji-Hee; Bayraktar, Evren; Bogdanov, Rashit; Liebregts, Tobias; Steckel, Nina Kristin; Fiedler, Melanie; Beelen, Dietrich;
    Early Cytomegalovirus Reactivation and Donor Constellation Reduce Early and Late Relapse Incidence of Acute Myeloid Leukemia in a Long-Term Study
    60th ASH Annual Meeting; December 1-4, 2018; San Diego, USA,
    In: Blood Jg. 132 (2018) Nr. Supplement 1, S. 3413 - 3413
    Online Volltext: dx.doi.org/ (Open Access)
  • Friebus-Kardash, J.; Eisenberger, Ute; Ackermann, J.; Kribben, Andreas; Witzke, Oliver; Wenzel, J.; Rohn, Hana; Fiedler, Melanie;
    Efficacy of Ribavirin Treatment for Active Hepatitis E Infection in Renal Allograft Recipients
    27th Annual Meeting of the German Transplantation Society, Berlin, Germany, 7–10 November 2018,
    In: Transplant International Jg. 31 (2018) Nr. S5, S. 30
    Online Volltext: dx.doi.org/ (Open Access)

    • 2017

    Artikel in Zeitschriften

  • Gliga, S.; Fiedler, Melanie; Herzer, Kerstin; Witzke, Oliver; Krawczyk, Adalbert; Korth, Johannes; Horn, Peter; Dittmer, Ulf; Lindemann, Monika
    CMV elispot assays are superior to the quantiferon CMV assay to predict protection from CMV reactivation in kidney ans liver transplant recipients
    In: HLA: Immune Response Genetics (Human Leukocyte Antigens) Jg. 89 (2017) Nr. 6, S. 375
    Online Volltext: dx.doi.org/
  • Franklin, Cindy; Rooms, Isabelle; Fiedler, Melanie; Reis, Henning; Milsch, Laura; Herz, Saskia; Livingstone, Elisabeth; Zimmer, Lisa; Schmid, Kurt Werner; Dittmer, Ulf; Schadendorf, Dirk; Schilling, Bastian
    Cytomegalovirus reactivation in patients with refractory checkpoint inhibitor-induced colitis
    In: European Journal of Cancer (EJC) Jg. 86 (2017) S. 248 - 256
    Online Volltext: dx.doi.org/
  • Koldehoff, Michael; Steckel, Nina Kristin; Riebschlager, S.; Fiedler, Melanie; Dührsen, Ulrich; Dittmer, Ulf; Beelen, Dietrich; Elmaagacli, Ahmet Hayri
    Early CMV replication after allogeneic stem cell transplantation is associated with a reduced relapse risk in acute myeloid leukemia : results of a prospective non-interventional trial
    In: Oncology Research and Treatment Jg. 40 (2017) Nr. Suppl. 3, Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, Stuttgart, 29. September-3. Oktober 2017: Abstracts, S. 101
    Online Volltext: dx.doi.org/
  • Stock, Ann-Kathrin; Dajkic, Danica; Köhling, Hedda; Heintschel von Heinegg, Evelyn; Fiedler, Melanie; Beste, Christian
    Humans with latent toxoplasmosis display altered reward modulation of cognitive control
    In: Scientific Reports Jg. 7 (2017) Nr. 1, S. 10170
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Lindemann, Monika; Zaslavskaya, M.; Fiedler, Melanie; Wilde, Benjamin; Heinemann, Falko M.; Heinold, Andreas; Horn, Peter; Witzke, Oliver
    Humoral and Cellular Responses to a Single Dose of Fendrix in Renal Transplant Recipients with Non-response to Previous Hepatitis B Vaccination
    In: Scandinavian Journal of Immunology Jg. 85 (2017) Nr. 1, S. 51 - 57
    Online Volltext: dx.doi.org/ (Open Access)
  • Nowak, Knut Michael; Witzke, Oliver; Sotiropoulos, Georgios; Benkö, Tamas; Fiedler, Melanie; Timm, Jörg; Kribben, Andreas; Wilde, Benjamin; Saner, Fuat; Paul, Andreas; Treckmann, Jürgen-Walter
    Transplantation of Renal Allografts From Organ Donors Reactive for HCV Antibodies to HCV-Negative Recipients: Safety and Clinical Outcome
    In: Kidney International Reports Jg. 2 (2017) Nr. 1, S. 53 - 59
    Online Volltext: dx.doi.org/ (Open Access)

    • 2016

    Artikel in Zeitschriften

  • Lindemann, Monika; Beelen, Dietrich; Horn, Peter; Roggendorf, Michael; Heinemann, M.; Ottinger, Hellmut; Schumann, A.; Fiedler, Melanie; Koldehoff, Michael
    Control of hepatitis B virus infection in hematopoietic stem cell recipients after receiving grafts from vaccinated donors
    In: Bone Marrow Transplantation Jg. 51 (2016) Nr. 3, S. 428 - 431
    Online Volltext: dx.doi.org/

    • Abstracts

  • Beelen, Dietrich; Bujor, L. V.; Stempelmann, K.; Fiedler, Melanie; Crivello, P.; Trilling, Mirko; Dittmer, Ulf; Ditschkowski, Markus; Fleischhauer, Katharina
    Early Replication of Human Cytomegalovirus (HCMV) is associated with a reduced risk of hematologic relapse in myeloid neoplasias after matched Unrelated Stem Cell Transplantation (HSCT) in an anti-thymocyte-globuline dependent manner
    In: Oncology Research and Treatment Jg. 39 (2016) Nr. Suppl. 3, S. 312 - 313
    Online Volltext: dx.doi.org/
  • Zaslavskaya, M.; Fiedler, Melanie; Wilde, Benjamin; Heinemann, Falko M.; Heinold, Andreas; Horn, Peter; Witzke, Oliver; Lindemann, Monika
    Humoral and cellular responses to a single dose of fendrix in kidney transplant recipients with non-response to conventional Hepatitis B vaccines
    In: Transplant International Jg. 29 Suppl. 3 (2016) S. 16 V107
    Online Volltext: dx.doi.org/

    • 2015

    Artikel in Zeitschriften

  • Schumann, Alexandra; Fiedler, Melanie; Beckebaum, Susanne; Cicinnati, Vito; Herzer, Kerstin; Lenz, Veronika; Witzke, Oliver; Paul, Andreas; Roggendorf, Michael; Horn, Peter; Lindemann, Monika
    Donor- and recipient-derived immunity in ABO incompatible living-related liver transplantation
    In: Human Immunology Jg. 76 (2015) Nr. 9, S. 631 - 635
    Online Volltext: dx.doi.org/

    • 2014

    Artikel in Zeitschriften

  • Krawczyk, Adalbert; Hintze, Christian; Ackermann, Jessica; Goitowski, Birgit; Trippler, Martin; Grüner, Nico; Neumann-Fraune, Maria; Verheyen, Jens; Fiedler, Melanie
    Clinical performance of the novel DiaSorin LIAISON® XL murex : HBsAg Quant, HCV-Ab, HIV-Ab/Ag assays
    In: Journal of Clinical Virology Jg. 59 (2014) Nr. 1, S. 44 - 49
    Online Volltext: dx.doi.org/
  • Lange, Milena; Fiedler, Melanie; Bankwitz, Dorothea; Osburn, William; Viazov, Sergey; Brovko, Olena; Zekri, Abdel-Rahman; Khudyakov, Yury; Nassal, Michael; Pumpens, Paul; Pietschmann, Thomas; Timm, Jörg; Roggendorf, Michael; Walker, Andreas
    Hepatitis C virus hypervariable region 1 variants presented on hepatitis B virus capsid-like particles induce cross-neutralizing antibodies
    In: PLoS ONE Jg. 9 (2014) Nr. 7, S. e102235
    Online Volltext: dx.doi.org/ (Open Access)
  • Krawczyk, Adalbert; Ludwig, Charlotte; Jochum, Christoph; Fiedler, Melanie; Heinemann, Falko M.; Shouval, Daniel; Roggendorf, Michael; Roggendorf, Hedwig; Lindemann, Monika
    Induction of a robust T- and B-cell immune response in non- and low-responders to conventional vaccination against hepatitis B by using a third generation PreS/S vaccine
    In: Vaccine Jg. 32 (2014) Nr. 39, S. 5077 - 5082
    Online Volltext: dx.doi.org/
  • Jiang, M; Bröring, Ruth; Trippler, M; Poggenpohl, L; Fiedler, Melanie; Gerken, Guido; Lu, Mengji; Schlaak, Jörg Friedrich
    Toll-like receptor-mediated immune responses are attenuated in the presence of high levels of hepatitis B virus surface antigen
    In: Journal of Viral Hepatitis Jg. 21 (2014) Nr. 12, S. 860 - 872
    Online Volltext: dx.doi.org/

    • 2013

    Artikel in Zeitschriften

  • Kosinska, Anna D.; Zhang, Ejuan; Johrden, Lena; Liu, Jia; Seiz, Pia L.; Zhang, Xiaoyong; Ma, Zhiyong; Kemper, Thekla; Fiedler, Melanie; Glebe, Dieter; Wildner, Oliver; Dittmer, Ulf; Lu, Mengji; Roggendorf, Michael
    Combination of DNA Prime - Adenovirus Boost Immunization with Entecavir Elicits Sustained Control of Chronic Hepatitis B in the Woodchuck Model
    In: PLoS Pathogens Jg. 9 (2013) Nr. 6, S. e100339
    Online Volltext: dx.doi.org/ (Open Access)
  • Olivero, A.; Hoffmann, D.; Buti, M.; Frías, F. Rodríguez; Alavian, S.M.; Wedemeyer, Heiner; Timm, Jörg; Karimzadeh, H.; Rizzetto, M.; Keyvani, H.; Budeus, B.; Kosinska, A.; Roggendorf, Michael; Smedile, A.; Homs, M.; Fiedler, Melanie
    Immune ecasion of hepatitis delta from CD8+ t cell immune response
    In: Journal of Hepatology Jg. 58 (2013) Nr. Suppl. 1, S. S20
    Online Volltext: dx.doi.org/
  • Gabriel, Martin; Emmerich, Petra; Frank, Christina; Fiedler, Melanie; Rashidi-Alavijeh, Jassin; Jochum, Christoph; Günther, Stephan; Auerhammer, Katherina; Rupprecht, Hans-Jürgen; Blank, Ralf-Thomas; Sacher, Nadine; Pertzborn, Lisa; Stark, Klaus; Schrauzer, Thomas; Schmidt-Chanasit, Jonas
    Increase in West Nile virus infections imported to Germany in 2012
    In: Journal of Clinical Virology Jg. 58 (2013) Nr. 3, S. 587 - 589
    Online Volltext: dx.doi.org/
  • Yang, Yinke; Zhang, Xiaoyong; Zhang, Chunyan; Tao, Yuanqing; Fan, Wei; Wang, Zhongdong; Wang, Hu; Lu, Mengji; Yang, Dongliang; Fiedler, Melanie; Wang, Baoju
    Molecular characterization of woodchuck CD4 (wCD4) and production of a depletion monoclonal antibody against wCD4
    In: Molecular Immunology Jg. 56 (2013) Nr. 1/2, S. 64 - 71
    Online Volltext: dx.doi.org/
  • Fiedler, Melanie; Kosinska, Anna; Schumann, Alexandra; Brovko, Olena; Walker, Andreas; Lu, Mengji; Johrden, Lena; Mayer, Anja; Wildner, Oliver; Roggendorf, Michael
    Prime/boost immunization with DNA and adenoviral vectors protects from hepatitis D virus (HDV) infection after simultaneous infection with HDV and woodchuck hepatitis virus
    In: Journal of Virology Jg. 87 (2013) Nr. 13, S. 7708 - 7716
    Online Volltext: dx.doi.org/

    • 2012

    Artikel in Zeitschriften

  • Kosinska, Anna D.; Johrden, Lena; Zhang, Ejuan; Fiedler, Melanie; Mayer, Anja; Wildner, Oliver; Lu, Mengji; Roggendorf, Michael
    DNA Prime-adenovirus boost immunization induces a vigorous and multifunctional T-cell response against hepadnaviral proteins in the mouse and woodchuck model
    In: Journal of Virology Jg. 86 (2012) Nr. 17, S. 9297 - 9310
    Online Volltext: dx.doi.org/
  • Ross, Birgit; Witzke, Oliver; Kribben, Andreas; Heintschel von Heinegg, Evelyn; Buer, Jan; Gerken, Guido; Fiedler, Melanie; Popp, Walter
    Krankenhaushygiene : Umgang mit einem EHEC-Ausbruch
    In: Deutsche Medizinische Wochenschrift - DMW Jg. 137 (2012) Nr. 18, S. 933 - 936
    Online Volltext: dx.doi.org/
  • Hörning, Andre; Hegen, Bianca; Wingen, Anne-Margret; Cetiner, Metin; Lainka, Elke; Kathemann, Simone; Fiedler, Melanie; Timm, Jörg; Wenzel, Jürgen J.; Hoyer, Peter Friedrich; Gerner, Patrick
    Prevalence of hepatitis e virus infection in pediatric solid organ transplant recipients : a single-center experience
    In: Pediatric Transplantation Jg. 16 (2012) Nr. 7, S. 742 - 747
    Online Volltext: dx.doi.org/

    • 2011

    Artikel in Zeitschriften

  • Lindemann, Monika; Schumann, A.; Fiedler, Melanie; Beckebaum, Susanne; Cicinnati, Vito; Witzke, Oliver; Lenz, V.; Roggendorf, Michael; Horn, Peter
    Donor- and recipient-derived immunity in ABO incompatible living donor liver transplantation
    In: Tissue Antigens Jg. 77 (2011) Nr. 5, S. 439
    Online Volltext: dx.doi.org/
  • Dohna-Schwake, Christian; Fiedler, Melanie; Gierenz, N.; Gerner, Patrick; Ballauff, Antje; Breddemann, A.; Läer, S.; Baba, Hideo Andreas; Hoyer, Peter Friedrich
    Primary HHV 6 infection after liver transplantation with acute graft rejection and multi-organ failure: Successful treatment with a 2.5-fold dose of cidofovir and reduction of immunosuppression
    In: Pediatric Transplantation Jg. 15 (2011) Nr. 6, S. E126 - E129
    Online Volltext: dx.doi.org/

    • Abstracts

  • Janson, D.; Fiedler, Melanie; Horacek, Michael; Katsounas, Antonios; Roggendorf, Michael; Dührsen, Ulrich; Röth, Alexander;
    Outbreak - pandemic 2009 influenza A (H1N1) infections in a hematology ward : Clinical presentation and outcome
    Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Basel, 30.09.–04.10. 2011,
    In: Onkologie Jg. 34 (2011) Nr. Suppl. 6, S. 43
    Online Volltext: dx.doi.org/
  • Fiedler, Melanie; Schumann, A.; Kosinska, A.; Lu, Mengji; Johrden, L.; Wildner, O.; Roggendorf, Michael
    Prime/boost immunization with DNA and adenoviral vectors protects woodchucks from hepatitis D virus infection
    In: Journal of Hepatology Jg. 54 (2011) Nr. Suppl. 1, S. S439
    Online Volltext: dx.doi.org/

    • 2010

    Artikel in Zeitschriften

  • Vernadakis, S.; Adamzik, Michael; Heuer, Matthias; Antoch, Gerald; Baba, Hideo Andreas; Fiedler, Melanie; Buer, Jan; Paul, Andreas; Kaiser, Gernot Maximil
    Hemikolektomie bei Kolonischämie : Fallbericht von Schweinegrippe mit letalem Verlauf
    In: Der Chirurg Jg. 81 (2010) Nr. 9, S. 841 - 845
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Dohna-Schwake, Christian; Schweiger, Brunhilde; Felderhoff-Müser, Ursula; Fiedler, Melanie; Kaiser, Gernot Maximil; Paul, Andreas; Gerner, Patrick; Lainka, Elke; Hoyer, Peter Friedrich
    Severe H1N1 infection in a pediatric liver transplant recipient treated with intravenous zanamivir : efficiency and complications : Letters to the Editor
    In: Transplantation Jg. 90 (2010) Nr. 2, S. 223 - 224
    Online Volltext: dx.doi.org/ (Open Access)

    • Abstracts

  • Lindemann, Monika; Fiedler, Melanie; Elmaagacli, Ahmet Hayri; Schumann, Alexandra; Roggendorf, Michael; Horn, Peter; Beelen, Dietrich;
    Clinical outcome of hepatitis B virus infection in patients receiving hematopoietic stem cell grafts from immunized donors
    19th Annual Congress of the German Transplantation Society, Hamburg, Germany, 7‐9 October 2010,
    In: Transplant International Jg. 23 (2010) Nr. Suppl. 2, S. 29
    Online Volltext: dx.doi.org/
  • Schumann, Alexandra; Fiedler, Melanie; Beckebaum, Susanne; Cicinnati, Vito; Knop, Dietmar; Horn, Peter; Roggendorf, Michael; Lindemann, Monika;
    Hepatitis B Virus specific immune transfer in abo incompatible living donor liver transplantation
    19th Annual Congress of the German Transplantation Society, Hamburg, Germany, 7‐9 October 2010,
    In: Transplant International Jg. 23 (2010) Nr. Suppl. 2, S. 29
    Online Volltext: dx.doi.org/

    • 2006

    Artikel in Zeitschriften

  • Wallot, Michael; Dohna-Schwake, Christian; Auth, Marcus Karl-Heinz; Nadalin, Silvio; Fiedler, Melanie; Malagó, M.; Broelsch, C.; Voit, Thomas
    Disseminated adenovirus infection with respiratory failure in pediatric liver transplant recipients : Impact of intravenous cidofovir and inhaled nitric oxide
    In: Pediatric Transplantation Jg. 10 (2006) Nr. 1, S. 121 - 127
    Online Volltext: dx.doi.org/
  • Lindemann, Monika; Schumann, Alexandra; Fiedler, Melanie
    Immuntransfer durch Transplantation : Impfungen der Spender können auch die Empfänger schützen
    In: Essener Unikate: Berichte aus Forschung und Lehre (2006) Nr. 27 : Medizin – Immunologie, S. 74 - 81
    Online Volltext (Open Access)

    • 2004

    Artikel in Zeitschriften

  • Wallot, Michael; Metzger-Boddien, Christoph; Auth, Marcus Karl-Heinz; Kehle, Johannes; Enders, Gisela; Dirsch, Olaf; Fiedler, Melanie; Voit, Thomas
    Acute liver failure associated with Coxsackie virus B2 infection in a neonate
    In: European Journal of Pediatrics Jg. 163 (2004) Nr. 2, S. 116 - 117
    Online Volltext: dx.doi.org/
  • Dahmen, Uta; Dirsch, Olaf; Li, Jun; Fiedler, Melanie; Lu, Mengji; Rispeter, Kai; Picucci, Martha; Broelsch, Christoph E.; Roggendorf, Michael
    Adoptive transfer of immunity : A new strategy to interfere with severe hepatitis virus reinfection after woodchuck liver transplantation
    In: Transplantation Jg. 77 (2004) Nr. 7, S. 965 - 972
    Online Volltext: dx.doi.org/
  • Fiedler, Melanie; Rödicker, Florian; Salucci, Valentina; Lu, Mengji; Aurisicchio, Luigi; Dahmen, Uta; Jun, Li; Dirsch, Olaf; Pützer, Brigitte M.; Palombo, Fabio; Roggendorf, Michael
    Helper-dependent adenoviral vector-mediated delivery of woodchuck-specific genes for alpha interferon (IFN-α) and IFN-γ : IFN-α but not IFN-γ reduces woodchuck hepatitis virus replication in chronic infection in vivo
    In: Journal of Virology Jg. 78 (2004) Nr. 18, S. 10111 - 10121
    Online Volltext: dx.doi.org/ (Open Access)

    • 2003

    Artikel in Zeitschriften

  • Viazov, Sergey; Ratjen, F.; Scheidhauer, R.; Fiedler, Melanie; Roggendorf, Michael
    High prevalence of human metapneumovirus infection in young children and genetic heterogeneity of the viral isolates
    In: Journal of Clinical Microbiology Jg. 41 (2003) Nr. 7, S. 3043 - 3045
    Online Volltext: dx.doi.org/

    • 2002

    Artikel in Zeitschriften

  • Dahmen, Uta; Li, Jun; Dirsch, Olaf; Fiedler, Melanie; Lu, Mengji; Roggendorf, Michael; Broelsch, Christoph Erich
    A new model of hepatitis B virus reinfection : Liver transplantation in the woodchuck
    In: Transplantation Jg. 74 (2002) Nr. 3, S. 373 - 380
    Online Volltext: dx.doi.org/
  • Dahmen, Uta; Li, J.; Dirsch, O.; Fiedler, Melanie; Roggendorf, Michael; Broelsch, C.E.
    Establishment of liver transplantation in woodchuck
    In: Transplantation Proceedings Jg. 34 (2002) Nr. 6, S. 2314 - 2315
    Online Volltext: dx.doi.org/
  • Li, Jun; Dahmen, Uta; Dirsch, Olaf R.; Gu, YanLi; Polywka, Susanne; Fiedler, Melanie; Doebel, Lothar; Roggendorf, Michael; Broelsch, Christoph Erich
    The potential role of bone marrow transplantation in augmenting donor-derived immunity to hepatitis B after rat liver transplantation
    In: Liver Transplantation Jg. 8 (2002) Nr. 4, S. 397 - 404
    Online Volltext: dx.doi.org/ (Open Access)

    • 2001

    Artikel in Zeitschriften

  • Pützer, Brigitte M.; Stiewe, Thorsten; Rödicker, Florian; Schildgen, Oliver; Rühm, Stefan; Dirsch, Olaf; Fiedler, Melanie; Damen, Uta; Tennant, Bud; Scherer, Caren; Graham, Frank L.; Roggendorf, Michael
    Large nontransplanted hepatocellular carcinoma in woodchucks : Treatment with adenovirus-mediated delivery of interleukin 12/B7.1 genes
    In: Journal of the National Cancer Institute Jg. 93 (2001) Nr. 6, S. 472 - 479
    Online Volltext: dx.doi.org/ (Open Access)

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