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ZMB Member Alexander Probst

ZMB Member
Alexander Probst

Next ZMB-Member
Alexander Probst portrait
© UDE

Prof. Dr. Alexander Probst

Research Center One Health Ruhr
University Alliance Ruhr
Faculty of Chemistry
University of Duisburg-Essen
Universitätsstr. 2
45141 Essen

Research Overview

Alexander Probst ist a highly interdisciplinary researcher. As a trained microbiologist, whose research is dominated by bioinformatics, he is an appointed W3 professor at the Faculty of Chemistry. His research entangles primarily the One Health and Ecosystem Health aspect, addresses fundamental questions in ecophysiology of microorganisms and viruses, deals with deep groundwater and the deep biosphere in general, and focuses on aspects of biodiversity and global dispersal of microbes across aquatic ecosystems.

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Press Releases

Selected Publications

    Journal articles

  • Valentin-Alvarado, Luis E.; Fakra, Sirine C.; Probst, Alexander J.; Giska, Jonathan R.; Jaffe, Alexander L.; Oltrogge, Luke M.; West-Roberts, Jacob; Rowland, Joel; Manga, Michael; Savage, David F.; Greening, Chris; Baker, Brett J.; Banfield, Jillian F.
    Autotrophic biofilms sustained by deeply sourced groundwater host diverse bacteria implicated in sulfur and hydrogen metabolism
    In: Microbiome Vol. 12 (2024) Nr. 1, 15
  • Shah, Manan; Bornemann, Till; Nuy, Julia; Hahn, Martin W.; Probst, Alexander J.; Beisser, Daniela; Boenigk, Jens.
    Genome-resolved metagenomics reveals the effect of nutrient availability on bacterial genomic properties across 44 European freshwater lakes
    In: Environmental Microbiology Vol. 26 (2024) Nr. 6, e16634
  • Lezcano, María Ángeles; Bornemann, Till; Sánchez-García, Laura; Carrizo, Daniel; Adam, Panagiotis; Esser, Sarah P.; Cabrol, Nathalie A.; Probst, Alexander J.; Parro, Víctor.
    Hyperexpansion of genetic diversity and metabolic capacity of extremophilic bacteria and archaea in ancient Andean lake sediments
    In: Microbiome Vol. 12 (2024) Nr. 1, 176
  • Figueroa-Gonzalez, Perla Abigail; Bornemann, Till L. V.; Hinzke, Tjorven; Maaß, Sandra; Trautwein-Schult, Anke; Starke, Joern; Moore, Carrie J.; Esser, Sarah P.; Plewka, Julia; Hesse, Tobias; Schmidt, Torsten C.; Schreiber, Ulrich; Bor, Batbileg; Becher, D et al.
    Metaproteogenomics resolution of a high-CO₂ aquifer community reveals a complex cellular adaptation of groundwater Gracilibacteria to a host-dependent lifestyle
    In: Microbiome Vol. 12 (2024) Nr. 1, 194
  • Lee, Kang Soo; Landry, Zachary; Athar, Awais; Alcolombri, Uria; Pramoj Na Ayutthaya, Pratchaya; Berry, David; de Bettignies, Philippe; Cheng, Ji-Xin; Csucs, Gabor; Cui, Li; Deckert, Volker; Dieing, Thomas; Dionne, Jennifer; Doskocil, Ondrej; D’Souza, Glen; et al.
    MicrobioRaman : an open-access web repository for microbiological Raman spectroscopy data
    In: Nature Microbiology (2024) Nr. 9, pp. 1152 - 1156
  • Wirbel, Jakob; Bhatt, Ami S.; Probst, Alexander J.
    The journey to understand previously unknown microbial genes
    In: Nature Vol. 626 (2024) Nr. 7998, pp. 267 - 269
  • Esser, Sarah P.; Rahlff, Janina; Zhao, Weishu; Predl, Michael; Plewka, Julia; Sures, Katharina; Wimmer, Franziska; Lee, Janey; Adam, Panagiotis; McGonigle, Julia; Turzynski, Victoria; Banas, Indra; Schwank, Katrin; Krupovic, Mart; Bornemann, Till L. V.; Fi et al.
    A predicted CRISPR-mediated symbiosis between uncultivated archaea
    In: Nature Microbiology Vol. 8 (2023) Nr. 9, pp. 1619 - 1633
  • Simon, Sophie A.; Schmidt, Katharina; Griesdorn, Lea; Soares, André R.; Bornemann, Till L. V.; Probst, Alexander J.
    Dancing the Nanopore limbo – Nanopore metagenomics from small DNA quantities for bacterial genome reconstruction
    In: BMC Genomics Vol. 24 (2023) Nr. 1, 727
  • Rahlff, Janina; Esser, Sarah P.; Plewka, Julia; Heinrichs, Mara Elena; Soares, André; Scarchilli, Claudio; Grigioni, Paolo; Wex, Heike; Giebel, Helge-Ansgar; Probst, Alexander J.
    Marine viruses disperse bidirectionally along the natural water cycle
    In: Nature Communications Vol. 14 (2023) Nr. 1, 6354
  • Banas, Indra; Esser, Sarah P.; Turzynski, Victoria; Soares, André; Novikova, Polina; May, Patrick; Moraru, Cristina; Hasenberg, Mike; Rahlff, Janina; Wilmes, Paul; Klingl, Andreas; Probst, Alexander J.
    Spatio-functional organization in virocells of small uncultivated archaea from the deep biosphere
    In: ISME Journal Vol. 17 (2023) Nr. 10, pp. 1789 - 1792
  • Stach, Tom L.; Sieber, Guido; Shah, Manan; Simon, Sophie A.; Soares, André; Bornemann, Till L. V.; Plewka, Julia; Künkel, Julian; Becker, Christian; Meyer, Folker; Boenigk, Jens; Probst, Alexander J.
    Temporal disturbance of a model stream ecosystem by high microbial diversity from treated wastewater
    In: MicrobiologyOpen Vol. 12 (2023) Nr. 2, e1347
  • Turzynski, Victoria; Griesdorn, Lea; Moraru, Cristina; Soares, André; Simon, Sophie A.; Stach, Tom L.; Rahlff, Janina; Esser, Sarah P.; Probst, Alexander J.
    Virus-Host Dynamics in Archaeal Groundwater Biofilms and the Associated Bacterial Community Composition
    In: Viruses Vol. 15 (2023) Nr. 4, 910
  • Bornemann, Till L. V.; Esser, Sarah P.; Stach, Tom L.; Burg, Tim; Probst, Alexander J.
    uBin : A manual refining tool for genomes from metagenomes
    In: Environmental Microbiology Vol. 25 (2023) Nr. 6, pp. 1077 - 1083
  • Neri, Uri; Wolf, Yuri I.; Roux, Simon; Camargo, Antonio Pedro; Lee, Benjamin; Kazlauskas, Darius; Chen, I. Min; Ivanova, Natalia; Zeigler Allen, Lisa; Paez-Espino, David; Bryant, Donald A.; Bhaya, Devaki; Narrowe, Adrienne B.; Probst, Alexander J.; Sczyrba et al.
    Expansion of the global RNA virome reveals diverse clades of bacteriophages
    In: Cell Vol. 185 (2022) Nr. 21, pp. 4023 - 4037.e18
  • Bornemann, Till L. V.; Adam, Panagiotis; Turzynski, Victoria; Schreiber, Ulrich; Figueroa-Gonzalez, Perla Abigail; Rahlff, Janina; Köster, Daniel; Schmidt, Torsten Claus; Schunk, Ralf; Krauthausen, Bernhard; Probst, Alexander J.
    Genetic diversity in terrestrial subsurface ecosystems impacted by geological degassing
    In: Nature Communications Vol. 13 (2022) Nr. 1, 284
  • Hedlund, Brian P; Chuvochina, Maria; Hugenholtz, Philip; Konstantinidis, Konstantinos T; Murray, Alison E; Palmer, Marike; Parks, Donovan H; Probst, Alexander J.; Reysenbach, Anna-Louise; Rodriguez-R, Luis M; Rossello-Mora, Ramon; Sutcliffe, Iain C; Venter et al.
    SeqCode : A nomenclatural code for prokaryotes described from sequence data
    In: Nature Microbiology Vol. 7 (2022) Nr. 10, pp. 1702 - 1708
  • Hwang, Yunha; Schulze-Makuch, Dirk; Arens, Felix L.; Saenz, Johan S.; Adam, Panagiotis; Sager, Christof; Bornemann, Till L. V.; Zhao, Weishu; Zhang, Ying; Airo, Alessandro; Schloter, Michael; Probst, Alexander J.
    Leave no stone unturned : individually adapted xerotolerant Thaumarchaeota sheltered below the boulders of the Atacama Desert hyperarid core
    In: Microbiome Vol. 9 (2021) Nr. 1, 234
  • Rahlff, Janina; Turzynski, Victoria; Esser, Sarah P.; Monsees, Indra; Bornemann, Till L. V.; Figueroa-Gonzalez, Perla Abigail; Schulz, Frederik; Woyke, Tanja; Klingl, Andreas; Moraru, Cristina; Probst, Alexander J.
    Lytic archaeal viruses infect abundant primary producers in Earth’s crust
    In: Nature Communications Vol. 12 (2021) Nr. 1, 4642
  • Al-Shayeb, Basem; Sachdeva, Rohan; Chen, Lin-Xing; Ward, Fred; Munk, Patrick; Devoto, Audra; Castelle, Cindy J.; Olm, Matthew R.; Bouma-Gregson, Keith; Amano, Yuki; He, Christine; Méheust, Raphaël; Brooks, Brandon; Thomas, Alex; Lavy, Adi; Matheus-Carneval et al.
    Clades of huge phages from across Earth’s ecosystems
    In: Nature Vol. 578 (2020) Nr. 7795, pp. 425 - 431
  • Geesink, Patricia; Wegner, Carl-Eric; Probst, Alexander J.; Herrmann, Martina; Dam, Hang T.; Kaster, Anne-Kristin; Küsel, Kirsten.
    Genome-inferred spatio-temporal resolution of an uncultivated Roizmanbacterium reveals its ecological preferences in groundwater
    In: Environmental Microbiology Vol. 22 (2020) Nr. 2, pp. 726 - 737
  • Müller, Hubert; Marozava, Sviatlana; Probst, Alexander J.; Meckenstock, Rainer.
    Groundwater cable bacteria conserve energy by sulfur disproportionation
    In: ISME Journal Vol. 14 (2020) Nr. 2, pp. 623 - 634
  • Probst, Alexander J.; Elling, Felix J.; Castelle, Cindy J.; Zhu, Qingzeng; Elvert, Marcus; Birarda, Giovanni; Holman, Hoi-Ying N.; Lane, Katherine R.; Ladd, Bethany; Ryan, M. Cathryn; Woyke, Tanja; Hinrichs, Kai-Uwe; Banfield, Jillian F.
    Lipid analysis of CO₂-rich subsurface aquifers suggests an autotrophy-based deep biosphere with lysolipids enriched in CPR bacteria
    In: ISME Journal Vol. 14 (2020) pp. 1547 - 1560
  • Murray, Alison E.; Freudenstein, John; Gribaldo, Simonetta; Hatzenpichler, Roland; Hugenholtz, Philip; Kämpfer, Peter; Konstantinidis, Konstantinos T.; Lane, Christopher E.; Papke, R. Thane; Parks, Donovan H.; Rossello-Mora, Ramon; Stott, Matthew B.; Sutcl et al.
    Roadmap for naming uncultivated Archaea and Bacteria
    In: Nature Microbiology Vol. 5 (2020) Nr. 8, pp. 987 - 994
  • Figueroa-Gonzalez, Perla Abigail; Bornemann, Till L. V.; Adam, Panagiotis; Plewka, Julia; Révész, Fruzsina; von Hagen, Christian A.; Táncsics, András; Probst, Alexander J.
    Saccharibacteria as Organic Carbon Sinks in Hydrocarbon-Fueled Communities
    In: Frontiers in Microbiology Vol. 11 (2020) pp. 587782