ZMB Members
ZMB Members
Member list
The ZMB currently comprises approx. 80 research groups from the Faculties of Biology, Medicine, and Chemistry at the Essen Campus and the University Hospital Essen, as well as groups from the Max Planck Institute of Molecular Physiology in Dortmund. If you are interested in participating in the ZMB network, please do not hesitate to contact us!
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member(s)
Prof. Dr.Stephan Barcikowski
Group: Technical Chemistry
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Peter Bayer
Group: Structural and Medicinal Biochemistry
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr. Dr.Jürgen Becker
Group: Translational Skin Cancer Research
ZMB Research Program: Oncology
MoreProf. Dr.Ivo Bendix
Group: Experimental Perinatal Neuroscience
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Dominik Boos
Group: Molecular Genetics II
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Jan Buer
Director of: Institute of Medical Microbiology
ZMB Research Program: Immunology, Infectious Diseases and Transplantation
MoreProf. Dr.Elke Cario
Group: Experimental Gastroenterology
ZMB Research Program: Immunology, Infectious Diseases and Transplantation
MoreProf. Dr.Ulf Dittmer
Director of: Institute of Virology
ZMB Research Program: Immunology, Infectious Diseases and Transplantation
MoreProf. Dr.Nicole Dünker
Group: Neuroanatomy
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Michael Ehrmann
Group: Microbiology
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Matthias Epple
Group: Inorganic Chemistry
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Kai Exner
Group: Theoretical Inorganic Chemistry
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Joachim Fandrey
Director of: Institute of Physiology
ZMB Research Program: Molecular and Chemical Cell Biology
MoreDr.Farnoush Farahpour
Group: Bioinformatics and Computational Biophysics
ZMB Research Program: Oncology
MoreJun.-Prof. Dr.Katja Ferenz
Group: Institute of Physiology
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Katharina Fleischhauer
Director of: Institute for Experimental Cellular Therapy
ZMB Research Program: Immunology, Infectious Diseases and Transplantation
MoreProf. Dr.Stefanie Flohé
Group: Immunology Sepsis/Trauma
ZMB Research Program: Immunology, Infectious Diseases and Transplantation
MoreProf. Dr.Dagmar Führer-Sakel
Director of: Clinic for Endocrinology, Diabetology and Metabolism
ZMB Research Program: Oncology
MoreProf. Dr.Anzhela Galstyan
Group: Photoactive Nanomaterials
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Bernd Giebel
Group: Giebel Lab
ZMB Research Program: Immunology, Infectious Diseases and Transplantation
MoreProf. Dr.Barbara Grünwald
Group: Tumor Heterogeneity and Translational Systems Biology
ZMB Research Program: Oncology
MoreProf. Dr.Erich Gulbins
Director of: Department of Molecular Biology
ZMB Research Program: Oncology
MoreProf. Dr.Matthias Gunzer
Director of: Institute of Experimental Immunology & Imaging
ZMB Research Program: Immunology, Infectious Diseases and Transplantation
MoreProf. Dr.Wiebke Hansen
Group: Molecular Infection Immunology
ZMB Research Program: Immunology, Infectious Diseases and Transplantation
MoreProf. Dr.Sven Heiles
Group: Lipidomics
ISAS e.V., Dortmund
ZMB Research Program: Immunology, Infectious Diseases and Transplantation
MoreProf. Dr.Doris Hellerschmied-Jelinek
Group: Mechanistic Cell Biology
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Ulrike Hendgen-Cotta
Manager of: Cardio Science Labs
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Dirk M. Hermann
Group: Vascular Neurology, Dementia and Age Research
ZMB Research Program: Molecular and Chemical Cell Biology
MorePD Dr.Josephine Herz
Group: Experimental Perinatal Neuroscience
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Heike Heuer
Group: Molecular Thyroidology
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Anke Hinney
Group: LVR Clinic for Psychiatry Essen
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Daniel Hoffmann
Group: Bioinformatics and Computational Biophysics
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Peter Horn
Director of: Institute for Transfusion Medicine
ZMB Research Program: Immunology, Infectious Diseases and Transplantation
MoreProf. Dr. Dr. h.c. mult.Robert Huber
Group: Structure Research
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Hans Werner Ingensiep
Group: Institute of Philosophy
Faculty of Humanities
University of Duisburg-Essen
More
Prof. Dr.Christian Johannes
Group: Molecular Genetics I
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Markus Kaiser
Group: Chemical Biology
ZMB Research Program: Molecular and Chemical Cell Biology
MoreDr.Farnusch Kaschani
Manager of: Analytics Core Facility Essen (ACE)
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Carsten Kirschning
Group: Regulation of Pathogen-specific Immunity
ZMB Research Program: Immunology, Infectious Diseases and Transplantation
MoreProf. Dr.Diana Klein
Group: Vascular Remodeling & Normal Tissue Protection
ZMB Research Program: Oncology
MoreProf. Dr.Christoph Kleinschnitz
Director of: Clinic for Neurology
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Shirley Knauer
Group: Molecular Biology II
ZMB Research Program: Molecular and Chemical Cell Biology
MorePD Dr.Adalbert Krawczyk
Group: Clinic for Infectious Diseases
ZMB Research Program: Immunology, Infectious Diseases and Transplantation
MoreProf. Dr.Ralf Küppers
Director of: Institute of Cell Biology (Tumor Research)
ZMB Research Program: Oncology
MoreProf. Dr.Karl Sebastian Lang
Director of: Institute of Immunology
ZMB Research Program: Immunology, Infectious Diseases and Transplantation
MoreJun.-Prof. Dr.Elisabeth Littwitz-Salomon
Group: Immune Metabolism in Infection and Cancer
ZMB Research Program: Immunology, Infectious Diseases and Transplantation
MoreProf. Dr.Dietmar Lohmann
Group: Ophthalmic Oncology and Genetics
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Katharina Lückerath
Group: Preclinical Theranostics in Nuclear Medicine
ZMB Research Program: Oncology
MoreProf. Dr.Hemmo Meyer
Group: Molecular Biology I
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Andrea Musacchio
Group: Mechanistic Cell Biology
Max Planck Institute of Molecular Physiology
Dortmund
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Perihan Nalbant
Group: Molecular Cell Biology
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Jochen Niemeyer
Group: Supramolecular Organocatalysis and Chemosensing
ZMB Research Program: Molecular and Chemical Cell Biology
MoreDr.Samuel Peña-Llopis
Junior Group: Translational Genomics in Solid Tumors
ZMB Research Program: Oncology
MoreProf. Dr.Alexander Probst
Group: Environmental Metagenomics
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Tienush Rassaf
Director of: Clinic for Cardiology and Vascular Medicine
ZMB Research Program: Oncology
MoreProf. Dr.Stefan Raunser
Group: Structural Biochemistry
Max Planck Institute of Molecular Physiology
Dortmund
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Christian Reinhardt
Director of: Clinic for Hematology and Stem Cell Transplantation
ZMB Research Program: Oncology
MoreProf. Dr.Alexander Roesch
Group: Tumor Heterogeneity & Plasticity
ZMB Research Program: Oncology
MoreProf. Dr.Barbara Saccà
Group: Bionanotechnology
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Sebastian Schlücker
Group: Molecular Biophotonics and Nanodiagnostics
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Thomas Schrader
Group: Biosupramolecular Chemistry
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Martin Schuler
Director of: Department of Medical Oncology
ZMB Research Program: Oncology
MoreDr.Nina Schulze
Manager of: Imaging Center Essen (ICCE)
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf Dr.Bettina Siebers
Group: Molecular Enzyme Technology
ZMB Research Program: Immunology, Infectious Diseases and Transplantation
MoreProf. Dr.Winfried Siffert
Director of: Institute of Pharmacogenetics
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr. Dr.Jens Siveke
Group: Bridge Institute for Experimental Tumor Therapy
ZMB Research Program: Oncology
MorePD Dr.Kathrin Sutter
TRR60 Junior Research Group: Interferone-alpha Subtypes
ZMB Research Program: Immunology, Infectious Diseases and Transplantation
MoreProf. Dr.Kathrin Thedieck
Group: Metabolism, Senescence and Autophagy
ZMB Research Program: Molecular and Chemical Cell Biology
MoreDr.Silvia Vega-Rubín-de-Celis
Junior Research Group: Autophagy in Cancer
ZMB Research Program: Oncology
MoreProf. Dr.Andrea Vortkamp
Group: Developmental Biology
ZMB Research Program: Molecular and Chemical Cell Biology
MorePD Dr.Jens Voskuhl
Group: Biosupramolecular Chemistry
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Gunther Wennemuth
Director of: Institute of Anatomy
ZMB Research Program: Molecular and Chemical Cell Biology
MoreProf. Dr.Astrid Westendorf
Group: Infection Immunology
ZMB Research Program: Immunology, Infectious Diseases and Transplantation
MoreProf. Dr.Stefan Westermann
Group: Molecular Genetics I
ZMB Research Program: Molecular and Chemical Cell Biology
MoreDr.Manuela Wülling
Group: Developmental Biology
ZMB Research Program: Molecular and Chemical Cell Biology
MoreCurrent Selected Publications
Biology
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A modular DNA origami nanocompartment for engineering a cell-free, protein unfolding and degradation pathwayIn: Nature Nanotechnology Vol. 19 (2024) Nr. 10, pp. 1521 - 1531Online Full Text: dx.doi.org/ (Open Access)
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A validation strategy to assess the role of phase separation as a determinant of macromolecular localizationIn: Molecular Cell Vol. 84 (2024) Nr. 9, pp. 1783 - 1801.e7Online Full Text: dx.doi.org/ (Open Access)
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Alternating binding and p97-mediated dissociation of SDS22 and I3 recycles active PP1 between holophosphatasesIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 121 (2024) Nr. 36, e2408787121Online Full Text: dx.doi.org/ (Open Access)
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HBV shows different levels of adaptation to HLA class I-associated selection pressure correlating with markers of replicationIn: Journal of Hepatology (2024) in pressOnline Full Text: dx.doi.org/ (Open Access)
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Lysosomal damage sensing and lysophagy initiation by SPG20-ITCHIn: Molecular Cell (2024) pp. 1556 - 1569.e10Online Full Text: dx.doi.org/ (Open Access)
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Microtubule end-on attachment maturation regulates Mps1 association with its kinetochore receptorIn: Current Biology Vol. 34 (2024) Nr. 11, pp. 2279 - 2293.e6Online Full Text: dx.doi.org/ (Open Access)
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Rational correction of pathogenic conformational defects in HTRA1In: Nature Communications Vol. 15 (2024) Nr. 1, 5944Online Full Text: dx.doi.org/ (Open Access)
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Regulation of minimal spindle midzone organization by mitotic kinasesIn: Nature Communications Vol. 15 (2024) Nr. 1, 9213Online Full Text: dx.doi.org/ (Open Access)
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Role of protein kinase PLK1 in the epigenetic maintenance of centromeresIn: Science Vol. 385 (2024) Nr. 6713, pp. 1091 - 1097Online Full Text: dx.doi.org/
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Structure of the human KMN complex and implications for regulation of its assemblyIn: Nature Structural & Molecular Biology Vol. 31 (2024) Nr. 6, pp. 861 - 873Online Full Text: dx.doi.org/ (Open Access)
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Subtilase SBT5.2 inactivates flagellin immunogenicity in the plant apoplastIn: Nature Communications Vol. 15 (2024) Nr. 1, 10431Online Full Text: dx.doi.org/ (Open Access)
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The Endo-Lysosomal Damage ResponseIn: Annual Review of Biochemistry Vol. 93 (2024) Nr. 1, pp. 367 - 387Online Full Text: dx.doi.org/ (Open Access)
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Thirty years of structural changesIn: Nature Structural & Molecular Biology Vol. 31 (2024) Nr. 1, pp. 4 - 5Online Full Text: dx.doi.org/
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TopBP1 utilises a bipartite GINS binding mode to support genome replicationIn: Nature Communications Vol. 15 (2024) Nr. 1, 1797Online Full Text: dx.doi.org/; Online Full Text: dx.doi.org/ (Open Access)
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VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substratesIn: Nature Communications Vol. 15 (2024) Nr. 1, 2459Online Full Text: dx.doi.org/ (Open Access)
Journal articles
Current Selected Publications
Chemistry
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CCooperative Active Sites on Ag2Pt3TiS6 for Enhanced Low-Temperature Ammonia Fuel Cell ElectrocatalysisIn: Angewandte Chemie International Edition (2024) e202418691 in pressOnline Full Text: dx.doi.org/ (Open Access)
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Convergence of Surface-Enhanced Raman Scattering with Molecular Diagnostics: A Perspective on Future DirectionsIn: ACS Nano Vol. 18 (2024) Nr. 8, pp. 5998 - 6007Online Full Text: dx.doi.org/
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Günter Wulff (1935 –2023) : Father of Molecular ImprintingIn: Angewandte Chemie International Edition Vol. 63 (2024) Nr. 12, e202402244Online Full Text: dx.doi.org/ (Open Access)
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Impact of Surface Enhanced Raman Spectroscopy in CatalysisIn: ACS Nano (2024) in pressOnline Full Text: dx.doi.org/ (Open Access)
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In situ Cyclization of Aromatic Thioethers in Emissive Materials to Generate Phosphorescent DibenzothiophenesIn: Angewandte Chemie International Edition (2024) in pressOnline Full Text: dx.doi.org/ (Open Access)
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The journey to understand previously unknown microbial genesIn: Nature Vol. 626 (2024) Nr. 7998, pp. 267 - 269Online Full Text: dx.doi.org/ (Open Access)
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iSERS : From nanotag design to protein assays and ex vivo imagingIn: Chemical Society Reviews Vol. 53 (2024) Nr. 13, pp. 6675 - 6693Online Full Text: dx.doi.org/ (Open Access)
Journal articles
Current Selected Publications
Medicine
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A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanomaIn: Cell Vol. 187 (2024) Nr. 1, pp. 166 - 183.e25Online Full Text: dx.doi.org/ (Open Access)
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Adjuvant pembrolizumab versus placebo in resected stage III melanoma (EORTC 1325-MG/KEYNOTE-054) : Long-term, health-related quality-of-life results from a double-blind, randomised, controlled, phase 3 trialIn: The Lancet Oncology Vol. 25 (2024) Nr. 9, pp. 1202 - 1212Online Full Text: dx.doi.org/
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Alteration of LARGE1 abundance in patients and a mouse model of 5q-associated spinal muscular atrophyIn: Acta Neuropathologica Vol. 147 (2024) Nr. 1, 53Online Full Text: dx.doi.org/ (Open Access)
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Amivantamab plus lazertinib versus osimertinib in first-line EGFR-mutant advanced non-small-cell lung cancer with biomarkers of high-risk disease : a secondary analysis from MARIPOSAIn: Annals of Oncology Vol. 35 (2024) Nr. 9, pp. 805 - 816Online Full Text: dx.doi.org/ (Open Access)
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An atlas of cells in the human tonsilIn: Immunity Vol. 57 (2024) Nr. 2, pp. 379 - 399.e18Online Full Text: dx.doi.org/ (Open Access)
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Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRAIn: Nature Communications Vol. 15 (2024) Nr. 1, 63Online Full Text: dx.doi.org/ (Open Access)
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BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathwayIn: Science Advances Vol. 10 (2024) Nr. 36, eadn9361Online Full Text: dx.doi.org/ (Open Access)
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Cardiac wasting and cancerIn: European Heart Journal Vol. 45 (2024) Nr. 34, pp. 3135 - 3137Online Full Text: dx.doi.org/ (Open Access)
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Cell-mediated cytotoxicity within CSF and brain parenchyma in spinal muscular atrophy unaltered by nusinersen treatmentIn: Nature Communications Vol. 15 (2024) Nr. 1, 4120Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Clinical Benefit of Avapritinib in KIT-Mutant Gastrointestinal Stromal Tumors : A Post Hoc Analysis of the Phase I NAVIGATOR and Phase I/II CS3007-001 StudiesIn: Clinical Cancer Research Vol. 30 (2024) Nr. 4, pp. 719 - 728Online Full Text: dx.doi.org/
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Combining PSMA-PET and PROMISE to re-define disease stage and risk in patients with prostate cancer : A multicentre retrospective studyIn: The Lancet Oncology Vol. 25 (2024) Nr. 9, pp. 1188 - 1201Online Full Text: dx.doi.org/ (Open Access)
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Comparison of pulsed field ablation versus cryoballon and radiofrequency ablation for pulmonary vein isolation in atrial fibrillation patients with heart failureIn: European Heart Journal Vol. 45 (2024) Nr. Supplement_1,Online Full Text: dx.doi.org/
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Correction to: Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identificationIn: Nature Communications Vol. 15 (2024) Nr. 1, 2364Online Full Text: dx.doi.org/ (Open Access)
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Cranioencephalic functional lymphoid units in glioblastomaIn: Nature Medicine (2024) in pressOnline Full Text: dx.doi.org/ (Open Access)
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Differential activity of MAPK signalling defines fibroblast subtypes in pancreatic cancerIn: Nature Communications Vol. 15 (2024) Nr. 1, 10534Online Full Text: dx.doi.org/ (Open Access)
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Directionality of HLA-DP permissive mismatches improves risk prediction in HCT for acute leukemia and MDSIn: Blood Vol. 144 (2024) Nr. 16, pp. 1747 - 1751Online Full Text: dx.doi.org/
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Entirely noninvasive outcome prediction in central nervous system lymphomas using circulating tumor DNAIn: Blood Vol. 143 (2024) Nr. 6, pp. 522 - 534Online Full Text: dx.doi.org/
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Epigenetic alterations in patients with anorexia nervosa : A systematic reviewIn: Molecular Psychiatry (2024) in pressOnline Full Text: dx.doi.org/ (Open Access)
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Evolutionary trajectories of small cell lung cancer under therapyIn: Nature Vol. 627 (2024) Nr. 8005, pp. 880 - 889Online Full Text: dx.doi.org/ (Open Access)
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Final Results for Adjuvant Dabrafenib plus Trametinib in Stage III MelanomaIn: The New England Journal of Medicine (2024) in pressOnline Full Text: dx.doi.org/
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Genetic and functional analyses of CTBP2 in anorexia nervosa and body weight regulationIn: Molecular Psychiatry (2024) in pressOnline Full Text: dx.doi.org/ (Open Access)
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Genomic heterogeneity and ploidy identify patients with intrinsic resistance to PD-1 blockade in metastatic melanomaIn: Science Advances Vol. 10 (2024) Nr. 48, eadp4670Online Full Text: dx.doi.org/ (Open Access)
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HBV shows different levels of adaptation to HLA class I-associated selection pressure correlating with markers of replicationIn: Journal of Hepatology (2024) in pressOnline Full Text: dx.doi.org/ (Open Access)
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Neoadjuvant nivolumab with or without relatlimab in resectable non-small-cell lung cancer : A randomized phase 2 trialIn: Nature Medicine Vol. 30 (2024) Nr. 6, pp. 1602 - 1611Online Full Text: dx.doi.org/ (Open Access)
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Pathogenic mitochondrial DNA mutations inhibit melanoma metastasisIn: Science Advances Vol. 10 (2024) Nr. 44, eadk8801Online Full Text: dx.doi.org/ (Open Access)
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Retrotransposons are co-opted to activate hematopoietic stem cells and erythropoiesisIn: Science Vol. 386 (2024) Nr. 6722, pp. eado6836Online Full Text: dx.doi.org/
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Ripretinib versus sunitinib in gastrointestinal stromal tumor : ctDNA biomarker analysis of the phase 3 INTRIGUE trialIn: Nature Medicine Vol. 30 (2024) Nr. 2, pp. 498 - 506Online Full Text: dx.doi.org/ (Open Access)
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Routine extracorporeal life support in infarct-related cardiogenic shock : 1-year results of the ECLS-SHOCK trialIn: European Heart Journal Vol. 45 (2024) Nr. 39, pp. 4200 - 4203Online Full Text: dx.doi.org/ (Open Access)
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Scrutinizing the Role of Venoarterial Extracorporeal Membrane Oxygenation : Has Clinical Practice Outpaced the Evidence?In: Circulation Vol. 149 (2024) Nr. 13, pp. 1033 - 1052Online Full Text: dx.doi.org/
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Structure-based discovery of first inhibitors targeting the helicase activity of human PIF1In: Nucleic Acids Research Vol. 52 (2024) Nr. 20, pp. 12616 - 12632Online Full Text: dx.doi.org/ (Open Access)
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T lymphocyte recruitment to melanoma brain tumors depends on distinct venous vesselsIn: Immunity (2024) in pressOnline Full Text: dx.doi.org/ (Open Access)
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Vimseltinib versus placebo for tenosynovial giant cell tumour (MOTION) : a multicentre, randomised, double-blind, placebo-controlled, phase 3 trialIn: Lancet Vol. 403 (2024) Nr. 10445, pp. 2709 - 2719Online Full Text: dx.doi.org/
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XPO1-Mediated mRNA Export of Genome Maintenance Regulators Drives Chemotherapy Resistance in Aggressive LymphomaIn: Cancer Research Vol. 84 (2024) Nr. 1, pp. 3 - 5Online Full Text: dx.doi.org/
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[¹⁷⁷Lu]Lu-DOTA-TATE plus long-acting octreotide versus high‑dose long-acting octreotide for the treatment of newly diagnosed, advanced grade 2–3, well-differentiated, gastroenteropancreatic neuroendocrine tumours (NETTER-2) : an open-label, randomised, phase 3 studyIn: Lancet Vol. 403 (2024) Nr. 10446, pp. 2807 - 2817Online Full Text: dx.doi.org/