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ZMB Member Peter Bayer

ZMB Member
Peter Bayer

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portrait photo of ZMB member Peter Bayer
© UDE/P.Bayer

Prof. Dr. Peter Bayer

Group

Structural and Medicinal Biochemistry

Faculty of Biology
University of Duisburg-Essen
Universitätsstr. 2
45141 Essen

Research Overview

The department Structural and Medicinal Biochemistry focuses on the elucidation of protein-protein and protein-ligand interactions using biochemical and biophysical strategies in addition to NMR as the main tool for the structure determination of biomolecules. Our research is geared towards predominantly human enzymes/proteins and their macromolecular complexes involved in posttranslational modification processes.

  1. Protein Structure Determination
  2. Biochemical Characterisation of Parvulins
  3. Biophysical studies on the interaction of synthetic supramolecular ligands and proteins
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Press Releases

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uni-due.de | Presse release

DFG fördert Studie zu Schilddrüsenhormonen Neue Therapien vermutet

[10.04.2024] Die Deutsche Forschungsgemeinschaft (DFG) fördert ein Wissenschaftsteam der Medizinischen Fakultät der Universität Duisburg-Essen (UDE) bei der Forschung an neuen therapeutischen Anwendungsgebieten für Schilddrüsenhormone. Dr. Sebastian Hönes von der Klinik für Endokrinologie, Diabetologie und Stoffwechsel des Universitätsklinikums Essen (UK Essen) leitet die klinische Studie. Die Erkenntnisse sollen potenziell zu neuen Behandlungsmethoden führen, beispielsweise bei Herzinfarkt, Schlaganfall oder Stoffwechsel-Erkrankungen. Für sein Vorhaben erhält Dr. Hönes von der DFG eine Förderung von knapp 300.000 Euro über einen Zeitraum von drei Jahren.

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Selected Publications

    Journal articles

  • Sternberg, Anna; Borger, Jennifer Lynne; Thies, Mathilda; Matena, Anja; Blüggel, Mike; Kamba, Bianca; Beuck, Christine; Kaschani, Farnusch; Kaiser, Markus; Bayer, Peter.
    The Actin‐Binding Prolyl‐Isomerase Par17 Sustains Its Substrate Selectivity by Interdomain Allostery
    In: Proteins: Structure, Function and Genetics (2025) in press
    Online Full Text: dx.doi.org/ (Open Access)
  • Hommel, Katrin; Kauth, Alisa-Maite A.; Kirupakaran, Abbna; Theisen, Sebastian; Hayduk, Matthias; Niemeyer, Felix C.; Beuck, Christine; Zadmard, Reza; Bayer, Peter; Jan Ravoo, Bart; Voskuhl, Jens; Schrader, Thomas; Knauer, Shirley K.
    Functional Linkers Support Targeting of Multivalent Tweezers to Taspase1
    In: Chemistry - A European Journal Vol. 30 (2024) Nr. 56, e202401542
    Online Full Text: dx.doi.org/ (Open Access)
  • Wolff, Natalie; Białas, Nataniel; Loza, Kateryna; Heggen, Marc; Schaller, Torsten; Niemeyer, Felix; Weidenthaler, Claudia; Beuck, Christine; Bayer, Peter; Prymak, Oleg; Oliveira, Cristiano L. P.; Epple, Matthias.
    Increased Cytotoxicity of Bimetallic Ultrasmall Silver–Platinum Nanoparticles (2 nm) on Cells and Bacteria in Comparison to Silver Nanoparticles of the Same Size
    In: Materials Vol. 17 (2024) Nr. 15, 3702
    Online Full Text: dx.doi.org/ (Open Access)
  • Wagner, Lisa-Sofie; Prymak, Oleg; Schaller, Torsten; Beuck, Christine; Loza, Kateryna; Niemeyer, Felix; Gumbiowski, Nina; Kostka, Kathrin; Bayer, Peter; Heggen, Marc; Oliveira, Cristiano L. P.; Epple, Matthias.
    The Molecular Footprint of Peptides on the Surface of Ultrasmall Gold Nanoparticles (2 nm) Is Governed by Steric Demand
    In: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry Vol. 128 (2024) Nr. 17, pp. 4266 - 4281
    Online Full Text: dx.doi.org/
  • Neblik, Jonas; Kirupakaran, Abbna; Beuck, Christine; Mieres-Perez, Joel; Niemeyer, Felix; Le, My-Hue; Telgheder, Ursula; Schmuck, Jessica Felice; Dudziak, Alexander; Bayer, Peter; Sanchez-Garcia, Elsa; Westermann, Stefan; Schrader, Thomas.
    Multivalent Molecular Tweezers Disrupt the Essential NDC80 Interaction with Microtubules
    In: Journal of the American Chemical Society: JACS Vol. 145 (2023) Nr. 28, pp. 15251 - 15264
    Online Full Text: dx.doi.org/
  • Seiler, Theresa; Lennartz, Annika; Klein, Kai; Hommel, Katrin; Figueroa Bietti, Antonio; Hadrovic, Inesa; Kollenda, Sebastian; Sager, Jonas; Beuck, Christine; Chlosta, Emilia; Bayer, Peter; Juul-Madsen, Kristian; Vorup-Jensen, Thomas; Schrader, Thomas; Epp et al.
    Potentiating Tweezer Affinity to a Protein Interface with Sequence-Defined Macromolecules on Nanoparticles
    In: Biomacromolecules Vol. 24 (2023) Nr. 8, pp. 3666 - 3679
    Online Full Text: dx.doi.org/
  • Blüggel, Mike; Kröning, Alexander; Kracht, Matthias; van den Boom, Johannes; Dabisch, Matthias; Göhring, Anna; Kaschani, Farnusch; Kaiser, Markus; Bayer, Peter; Meyer, Hemmo; Beuck, Christine.
    The UBX domain in UBXD1 organizes ubiquitin binding at the C-terminus of the VCP/p97 AAA-ATPase
    In: Nature Communications Vol. 14 (2023) Nr. 1, 3258
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Wolff, Natalie; Loza, Kateryna; Heggen, Marc; Schaller, Torsten; Niemeyer, Felix; Bayer, Peter; Beuck, Christine; Oliveira, Cristiano L P; Prymak, Oleg; Weidenthaler, Claudia; Epple, Matthias.
    Ultrastructure and Surface Composition of Glutathione-Terminated Ultrasmall Silver, Gold, Platinum, and Alloyed Silver-Platinum Nanoparticles (2 nm)
    In: Inorganic Chemistry Vol. 62 (2023) Nr. 42, pp. 17470 - 17485
    Online Full Text: dx.doi.org/
  • Warmerdam, Zoey; Kamba, Bianca; Le, My-Hue; Schrader, Thomas; Isaacs, Lyle; Bayer, Peter; Hof, Fraser.
    Binding Methylarginines and Methyllysines as Free Amino Acids : A Comparative Study of Multiple Host Classes
    In: ChemBioChem Vol. 23 (2022) Nr. 2, e202100502
    Online Full Text: dx.doi.org/ (Open Access)
  • Höing, Alexander; Struth, Robin; Beuck, Christine; Rafieiolhosseini, Neda; Hoffmann, Daniel; Stauber, Roland H.; Bayer, Peter; Niemeyer, Jochen; Knauer, Shirley.
    Dual activity inhibition of threonine aspartase 1 by a single bisphosphate ligand
    In: RSC Advances Vol. 12 (2022) Nr. 53, pp. 34176 - 34184
    Online Full Text: dx.doi.org/ (Open Access)
  • Höing, Alexander; Kirupakaran, Abbna; Beuck, Christine; Pörschke, Marius; Niemeyer, Felix; Seiler, Theresa; Hartmann, Laura; Bayer, Peter; Schrader, Thomas; Knauer, Shirley.
    Recognition of a Flexible Protein Loop in Taspase 1 by Multivalent Supramolecular Tweezers
    In: Biomacromolecules Vol. 23 (2022) Nr. 11, pp. 4504 - 4518
    Online Full Text: dx.doi.org/
  • Wetzel, Oliver; Prymak, Oleg; Loza, Kateryna; Gumbiowski, Nina; Heggen, Marc; Bayer, Peter; Beuck, Christine; Weidenthaler, Claudia; Epple, Matthias.
    Water-Based Synthesis of Ultrasmall Nanoparticles of Platinum Group Metal Oxides (1.8 nm)
    In: Inorganic Chemistry Vol. 61 (2022) Nr. 12, pp. 5133 - 5147
    Online Full Text: dx.doi.org/
  • Wetzel, Oliver; Hosseini, Shabnam; Loza, Kateryna; Heggen, Marc; Prymak, Oleg; Bayer, Peter; Beuck, Christine; Schaller, Torsten; Niemeyer, Felix; Weidenthaler, Claudia; Epple, Matthias.
    Metal-Ligand Interface and Internal Structure of Ultrasmall Silver Nanoparticles (2 nm)
    In: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry Vol. 125 (2021) Nr. 21, pp. 5645 - 5659
    Online Full Text: dx.doi.org/
  • van der Meer, Selina Beatrice; Hadrovic, Inesa; Meiners, Annika; Loza, Kateryna; Heggen, Marc; Knauer, Shirley; Bayer, Peter; Schrader, Thomas; Beuck, Christine; Epple, Matthias.
    New tools to probe the protein surface : Ultrasmall gold nanoparticles carry amino acid binders
    In: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry Vol. 125 (2021) Nr. 1, pp. 115 - 127
    Online Full Text: dx.doi.org/ (Open Access)
  • Ruks, Tatjana; Loza, Kateryna; Heggen, Marc; Prymak, Oleg; Sehnem, Andre Luiz; Oliveira, Cristiano L. P.; Bayer, Peter; Beuck, Christine; Epple, Matthias.
    Peptide-Conjugated Ultrasmall Gold Nanoparticles (2 nm) for Selective Protein Targeting
    In: ACS Applied Bio Materials Vol. 4 (2021) Nr. 1, pp. 945 - 965
    Online Full Text: dx.doi.org/ (Open Access)
  • Meiners, Annika; Bäcker, Sandra; Hadrovic, Inesa; Heid, Christian; Beuck, Christine; Ruiz-Blanco, Yasser B.; Mieres-Perez, Joel; Pörschke, Marius; Grad, Jean-Noël; Vallet, Cecilia; Hoffmann, Daniel; Bayer, Peter; Sánchez-García, Elsa; Schrader, Thomas; Kna et al.
    Specific inhibition of the Survivin–CRM1 interaction by peptide-modified molecular tweezers
    In: Nature Communications Vol. 12 (2021) Nr. 1, pp. 1505
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Ruks, Tatjana; Loza, Kateryna; Heggen, Marc; Ottmann, Christian; Bayer, Peter; Beuck, Christine; Epple, Matthias.
    Targeting the Surface of the Protein 14-3-3 by Ultrasmall (1.5 nm) Gold Nanoparticles Carrying the Specific Peptide CRaf
    In: ChemBioChem Vol. 22 (2021) Nr. 8, pp. 1456 - 1463
    Online Full Text: dx.doi.org/ (Open Access)
  • Killinger, Kerstin; Böhm, Miriam; Steinbach, Philine; Hagemann, Götz; Blüggel, Mike; Jänen, Karolin; Hohoff, Simone; Bayer, Peter; Herzog, Franz; Westermann, Stefan.
    Auto-inhibition of Mif2/CENP-C ensures centromere-dependent kinetochore assembly in budding yeast
    In: The EMBO Journal Vol. 39 (2020) Nr. 14, pp. e102938
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Vallet, Cecilia; Aschmann, Dennis; Beuck, Christine; Killa, Matthias; Meiners, Annika; Mertel, Marcel; Ehlers, Martin; Bayer, Peter; Schmuck, Carsten; Giese, Michael R. A.; Knauer, Shirley.
    Functional Disruption of the Cancer-Relevant Interaction between Survivin and Histone H3 with a Guanidiniocarbonyl Pyrrole Ligand
    In: Angewandte Chemie International Edition Vol. 59 (2020) Nr. 14, pp. 5567 - 5571
    Online Full Text: dx.doi.org/ (Open Access)
  • Bayer, Peter; Matena, Anja; Beuck, Christine.
    NMR Spectroscopy of supramolecular chemistry on protein surfaces
    In: Beilstein Journal of Organic Chemistry Vol. 16 (2020) pp. 2505 - 2522
    Online Full Text: dx.doi.org/ (Open Access)
  • Göhring, Anna; Michin, Irina; Gerdes, Tina; Schulze, Nina; Blüggel, Mike; Rehic, Edisa; Kaschani, Farnusch; Kaiser, Markus; Bayer, Peter.
    Targeting of parvulin interactors by diazirine mediated cross-linking discloses a cellular role of human Par14/17 in actin polymerization
    In: Biological Chemistry Vol. 401 (2020) Nr. 8, pp. 955 - 968
    Online Full Text: dx.doi.org/ (Open Access)
  • van den Boom, Johannes; Hensel, Astrid; Trusch, Franziska; Matena, Anja; Siemer, Svenja; Guel, Désirée; Docter, Dominic; Höing, Alexander; Bayer, Peter; Stauber, Roland H.; Knauer, Shirley.
    The other side of the corona : Nanoparticles inhibit the protease taspase1 in a size-dependent manner
    In: Nanoscale Vol. 12 (2020) Nr. 37, pp. 19093 - 19103
    Online Full Text: dx.doi.org/
  • Born, Alexandra; Nichols, Parker J.; Henen, Morkos A.; Chi, Celestine N.; Strotz, Dean; Bayer, Peter; Tate, Shin-Ichi; Peng, Jeffrey W.; Vögeli, Beat.
    Backbone and side-chain chemical shift assignments of full-length, apo, human Pin1, a phosphoprotein regulator with interdomain allostery
    In: Biomolecular NMR Assignments Vol. 13 (2019) Nr. 1, pp. 85 - 89
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • van der Meer, Selina; Loza, Kateryna; Wey, Karolin; Heggen, Marc; Beuck, Christine; Bayer, Peter; Epple, Matthias.
    Click chemistry on the surface of ultrasmall gold nanoparticles (2 nm) for covalent ligand attachment followed by nmr spectroscopy
    In: Langmuir Vol. 35 (2019) Nr. 22, pp. 7191 - 7204
    Online Full Text: dx.doi.org/
  • Bartsch, Lina; Bartel, Maria; Gigante, Alba; Iglesias-Fernández, Javier; Ruiz-Blanco, Yasser B.; Beuck, Christine; Briels, Jeroen; Tötsch, Niklas; Bayer, Peter; Sánchez-García, Elsa; Ottmann, Christian; Schmuck, Carsten.
    Multivalent Ligands with Tailor-Made Anion Binding Motif as Stabilizers of Protein–Protein Interactions
    In: ChemBioChem Vol. 20 (2019) Nr. 23, pp. 2921 - 2926
    Online Full Text: dx.doi.org/
  • Ruks, Tatjana; Beuck, Christine; Schaller, Torsten; Niemeyer, Felix; Zähres, Manfred; Loza, Kateryna; Heggen, Marc; Hagemann, Ulrich; Mayer, Christian; Bayer, Peter; Epple, Matthias.
    Solution NMR Spectroscopy with Isotope-Labeled Cysteine (¹³C and ¹⁵N) Reveals the Surface Structure of l -Cysteine-Coated Ultrasmall Gold Nanoparticles (1.8 nm)
    In: Langmuir Vol. 35 (2019) Nr. 3, pp. 767 - 778
    Online Full Text: dx.doi.org/
  • Rehic, Edisa; Hönig, Dana; Kamba, Bianca; Göhring, Anna; Hofmann, Eckhard; Gasper, Raphael; Matena, Anja; Bayer, Peter.
    Structural Analysis of the 42 kDa Parvulin of Trypanosoma brucei
    In: Biomolecules Vol. 9 (2019) Nr. 3, 93
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Blüggel, Mike; van den Boom, Johannes; Meyer, Hemmo; Bayer, Peter; Beuck, Christine.
    Structure of the PUB Domain from Ubiquitin Regulatory X Domain Protein 1 (UBXD1) and Its Interaction with the p97 AAA+ ATPase
    In: Biomolecules Vol. 9 (2019) Nr. 12, 876
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Trusch, Franziska; Loebach, Lars; Wawra, Stephan; Durward, Elaine; Wuensch, Andreas; Iberahim, Nurul Aqilah; De Bruijn, Irene; MacKenzie, Kevin; Willems, Ariane; Toloczko, Aleksandra; Diéguez-Uribeondo, Javier; Rasmussen, Tim; Schrader, Thomas; Bayer, Pete et al.
    Cell entry of a host-targeting protein of oomycetes requires gp96
    In: Nature Communications Vol. 9 (2018) Nr. 1, pp. 2347
    Online Full Text: dx.doi.org/ (Open Access)
  • Matena, Anja; Rehic, Edisa; Hönig, Dana; Kamba, Bianca; Bayer, Peter.
    Structure and function of the human parvulins Pin1 and Par14/17
    In: Biological Chemistry Vol. 399 (2018) Nr. 2, pp. 101 - 125
    Online Full Text: dx.doi.org/ (Open Access)
  • Wawra, Stephan; Trusch, Franziska; Matena, Anja; Apostolakis, Kostis; Linne, Uwe; Zhukov, Igor; Stanek, Jan; Koźmiński, Wiktor; Davidson, Ian; Secombes, Chris J.; Bayer, Peter; van West, Pieter.
    The RxLR motif of the host targeting effector AVR3a of phytophthora infestans is cleaved before secretion
    In: The Plant Cell Vol. 29 (2017) Nr. 6, pp. 1184 - 1195
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Hartmann-Fatu, Cristina; Bayer, Peter.
    Determinants of tyrosylprotein sulfation coding and substrate specificity of tyrosylprotein sulfotransferases in metazoans
    In: Chemico-Biological Interactions Vol. 259 (2016) Nr. Part A, pp. 17 - 22
    Online Full Text: dx.doi.org/
  • Trusch, Franziska; Kowski, Klaus; Bravo-Rodriguez, Kenny; Beuck, Christine; Sowislok, Andrea; Wettig, Burkhard; Matena, Anja; Sánchez-García, Elsa; Meyer, Hemmo; Schrader, Thomas; Bayer, Peter.
    Molecular tweezers target a protein-protein interface and thereby modulate complex formation
    In: Chemical Communications: ChemComm Vol. 52 (2016) Nr. 98, pp. 14141 - 14144
    Online Full Text: dx.doi.org/ (Open Access)
  • Hoppstock, Lukas; Trusch, Franziska; Lederer, Christoph; van West, Pieter; Koenneke, Martin; Bayer, Peter.
    NmPin from the marine thaumarchaeote Nitrosopumilus maritimus is an active membrane associated prolyl isomerase
    In: BMC Biology (incorporating Journal of Biology) Vol. 14 (2016) Nr. 1, pp. 53
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • van den Boom, Johannes; Trusch, Franziska; Hoppstock, Lukas; Beuck, Christine; Bayer, Peter.
    Structural Characterization of the Loop at the Alpha-Subunit C-Terminus of the Mixed Lineage Leukemia Protein Activating Protease Taspase1
    In: PLoS ONE Vol. 11 (2016) Nr. 3, pp. e0151431
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Hartmann-Fatu, Cristina; Trusch, Franziska; Moll, Carina; Michin, Irina; Hassinen, Antti; Kellokumpu, Sakari; Bayer, Peter.
    Heterodimers of Tyrosylprotein Sulfotransferases Suggest Existence of a Higher Organization Level of Transferases in the Membrane of the trans-Golgi Apparatus
    In: Journal of Molecular Biology (JMB) Vol. 427 (2015) Nr. Issue 6, Part B, pp. 1404 - 1412
    Online Full Text: dx.doi.org/
  • Saningong, Akuma D.; Bayer, Peter.
    Human DNA-binding peptidyl-prolyl cis/trans isomerase Par14 is cell cycle dependently expressed and associates with chromatin in vivo
    In: BMC Biochemistry Vol. 16 (2015) Nr. 1,
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Roy Choudhury, Amrita; Sikorska, Emilia; van den Boom, Johannes; Bayer, Peter; Popenda, Lukasz; Szutkowski, Kosma; Jurga, Stefan; Bonomi, Massimiliano; Sali, Andrej; Zhukov, Igor; Passamonti, Sabina; Novič, Marjana.
    Structural model of the bilitranslocase transmembrane domain supported by NMR and FRET data
    In: PLoS ONE Vol. 10 (2015) Nr. 8, pp. e0135455
    Online Full Text: dx.doi.org/ (Open Access)
  • Trusch, Franziska; Matena, Anja; Vuk, Maja; Körver, Lisa; Knævelsrud, Helene; Freemont, Paul S.; Meyer, Hemmo; Bayer, Peter.
    The N-terminal region of the ubiquitin regulatory X (UBX) domain-containing protein 1 (UBXD1) modulates interdomain communication within the valosin-containing protein p97
    In: The Journal of Biological Chemistry (JBC) Vol. 290 (2015) Nr. 49, pp. 29414 - 29427
    Online Full Text: dx.doi.org/ (Open Access)
  • van den Boom, Johannes; Mamic, Marija; Baccelliere, Daniele; Zweerink, Susanne; Kaschani, Farnusch; Knauer, Shirley; Bayer, Peter; Kaiser, Markus.
    Peptidyl succinimidyl peptides as taspase 1 inhibitors
    In: ChemBioChem Vol. 15 (2014) Nr. 15, pp. 2233 - 2237
    Online Full Text: dx.doi.org/
  • Grum, Daniel; Franke, Stefan; Kraff, Oliver; Heider, Dominik; Schramm, Alexander; Hoffmann, Daniel; Bayer, Peter.
    Design of a Modular Protein-Based MRI Contrast Agent for Targeted Application
    In: PLoS ONE Vol. 8 (2013) Nr. 6, pp. e65346
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Elfaki, Imadeldin; Knitsch, Andre; Matena, Anja; Bayer, Peter.
    Identification and characterization of peptides that bind the PPIase domain of Parvulin17
    In: Journal of Peptide Science Vol. 19 (2013) Nr. 6, pp. 362 - 369
    Online Full Text: dx.doi.org/
  • Matena, Anja; Sinnen, Christian; van den Boom, Johannes; Wilms, Christoph; Dybowski, Jan Nikolaj; Maltaner, Ricarda; Müller, Jonathan W.; Link, Nina M.; Hoffmann, Daniel; Bayer, Peter.
    Transient domain interactions enhance the affinity of the mitotic regulator pin1 toward phosphorylated peptide ligands
    In: Structure Vol. 21 (2013) Nr. 10, pp. 1769 - 1777
    Online Full Text: dx.doi.org/ (Open Access)
  • Schröder, Elisabeth; Gebel, Lena; Eremeev, Andrey A.; Morgner, Jessica; Grum, Daniel; Knauer, Shirley; Bayer, Peter; Müller, Jonathan W.
    Document Human PAPS synthase isoforms are dynamically regulated enzymes with access to nucleus and cytoplasm
    In: PLoS ONE Vol. 7 (2012) Nr. 1, pp. e29559
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Wawra, Stephan; Bain, Judith; Durward, Elaine; De Bruijn, Irene; Minor, Kirsty L.; Matena, Anja; Löbach, Lars; Whisson, Stephen C.; Bayer, Peter; Porter, Andrew J.; Birch, Paul R. J.; Secombes, Chris J.; Van West, Pieter.
    Host-targeting protein 1 (SpHtp1) from the oomycete Saprolegnia parasitica translocates specifically into fish cells in a tyrosine-O-sulphate-dependent manner
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 109 (2012) Nr. 6, pp. 2096 - 2101
    Online Full Text: dx.doi.org/
  • Hoeppner, Astrid; Thomas, Frank; Rueppel, Alma; Hensel, Reinhard; Blankenfeldt, Wulf; Bayer, Peter; Faust, Annette.
    Structure of the corrinoid : coenzyme M methyltransferase MtaA from Methanosarcina mazei
    In: Acta Crystallographica Section D: Biological Crystallography Vol. 68 (2012) Nr. 11, pp. 1549 - 1557
    Online Full Text: dx.doi.org/
  • Elfaki, Imadeldin; Bayer, Peter; Müller, Jonathan W.
    A potential transcriptional regulator is out-of-frame translated from the metallothionein 2A messenger RNA
    In: Analytical Biochemistry Vol. 409 (2011) Nr. 1, pp. 159 - 161
    Online Full Text: dx.doi.org/
  • Müller, Jonathan W.; Link, Nina C; Matena, Anja; Hoppstock, Lukas; Rüppel, Alma; Bayer, Peter; Blankenfeldt, Wulf.
    Crystallographic Proof for an Extended Hydrogen Bonding Network in Small Prolyl Isomerases
    In: Journal of the American Chemical Society: JACS Vol. 133 (2011) Nr. 50, pp. 20096 - 20099
    Online Full Text: dx.doi.org/ Online Full Text
  • Lederer, Christoph; Heider, Dominik; van den Boom, Johannes; Hoffmann, Daniel; Müller, Jonathan W.; Bayer, Peter.
    Single-Domain Parvulins Constitute a Specific Marker for Recently Proposed Deep-Branching Archaeal Subgroups
    In: Evolutionary Bioinformatics Vol. 7 (2011) pp. 135 - 148
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Jaremko, Lukasz; Jaremko, Mariusz; Elfaki, Imadeldin; Müller, Jonathan W.; Ejchart, Andrzej; Bayer, Peter; Zhukov, Igor.
    Structure and Dynamics of the First Archaeal Parvulin Reveal a New Functionally Important Loop in Parvulin-type Prolyl Isomerases
    In: The Journal of Biological Chemistry (JBC) Vol. 286 (2011) pp. 6554 - 6565
    Online Full Text: dx.doi.org/ (Open Access)
  • Link, Nina M.; Hunke, Cornelia; Müller, Jonathan W.; Eichler, Jutta; Bayer, Peter.
    The solution structure of pGolemi, a high affinity Mena EVH1 binding miniature protein, suggests explanations for paralog-specific binding to Ena/VASP homology (EVH) 1 domains
    In: Biological Chemistry Vol. 390 (2009) Nr. 5-6, pp. 417 - 426
    Online Full Text: dx.doi.org/
  • Müller, Jonathan W.; Bayer, Peter.
    Small family with key contacts : par14 and par17 parvulin proteins, relatives of pin1, now emerge in biomedical research
    In: Perspectives in Medicinal Chemistry Vol. 2 (2008) pp. 11 - 20
    Online Full Text: dx.doi.org/ (Open Access)
  • Zhukov, Igor; Bayer, Peter; Schölermann, Beate; Ejchart, Andrzej.
    15N magnetic relaxation study of backbone dynamics of the ribosomeassociated cold shock response protein Yfia of Escherichia coli
    In: Acta Biochimica Polonica Vol. 54 (2007) Nr. 4, pp. 769 - 775
    (Open Access)
  • Kessler, Daniel; Papatheodorou, Panagiotis; Stratmann, Tina; Dian, Elke Andrea; Hartmann-Fatu, Cristina; Rassow, Joachim; Bayer, Peter; Müller, Jonathan W.
    The DNA binding parvulin Par17 is targeted to the mitochondrial matrix by a recently evolved prepeptide uniquely present in Hominidae
    In: BMC Biology (incorporating Journal of Biology) Vol. 5 (2007) 37
    Online Full Text: dx.doi.org/
  • Mueller, Jonathan Wolf; Kessler, Daniel; Neumann, Daniel; Stratmann, Tina; Papatheodorou, Panagiotis; Hartmann-Fatu, Cristina; Bayer, Peter.
    Characterization of novel elongated Parvulin isoforms that are ubiquitously expressed in human tissues and originate from alternative transcription initiation
    In: BMC Molecular Biology Vol. 7 (2006) 9
    Online Full Text: dx.doi.org/
  • Harjes, E.; Harjes, S.; Wohlgemuth, S.; Mueller, K.H.; Krieger, E.; Herrmann, C.; Bayer, Peter.
    GTP-Ras disrupts the intramolecular complex of C1 and RA domains of Nore1.
    In: Structure Vol. 14 (2006) pp. 881 - 888
    Online Full Text: dx.doi.org/ (Open Access)
  • Goettsch, Sandra; Badea, Rodica A.; Müller, Jonathan W.; Wotzlaw, Christoph; Schoelermann, Beate; Schulz, Lars; Rabiller, Matthias; Bayer, Peter; Hartmann-Fatu, Cristina.
    Human TPST1 Transmembrane Domain Triggers Enzyme Dimerisation and Localisation to the Golgi Compartment
    In: Journal of Molecular Biology (JMB) Vol. 361 (2006) Nr. 3, pp. 436 - 449
    Online Full Text: dx.doi.org/
  • Niculae, A.; Gruen, M.; Bayer, Peter; Breitling, R.; Alexandrov, K.
    Isotopic labelling of recombinant proteins expressed in the protozoan host Leishmania tarentolae.
    In: Protein Expression & Purification Vol. 48 (2006) pp. 167 - 172
  • Hecker, Christina-Maria; Rabiller, Matthias; Haglund, Kaisa; Bayer, Peter; Dikic, Ivan.
    Specification of SUMO1- and SUMO2-interacting motifs
    In: The Journal of Biological Chemistry (JBC) Vol. 281 (2006) Nr. 23, pp. 16117 - 16127
    Online Full Text: dx.doi.org/ (Open Access)
  • Bayer, E.; Thutewohl, M.; Christner, C.; Waldmann, H.; Bayer, Peter.
    Identification of hPin1 inhibitors that induce apoptosis in a mammalian Ras transformed cell line
    In: Chemical Communications: ChemComm Vol. 4 (2005) pp. 516 - 518
    Online Full Text: dx.doi.org/
  • Harjes, Stefan; Bayer, Peter; Scheidig, Axel J.
    The crystal structure of human PAPS synthetase 1 reveals asymmetry in substrate binding
    In: Journal of Molecular Biology (JMB) Vol. 347 (2005) Nr. 3, pp. 623 - 635
    Online Full Text: dx.doi.org/
  • Harjes, Stefan; Scheidig, Axel; Bayer, Peter.
    Expression, purification and crystallization of human 3′- phosphoadenosine-5′-phosphosulfate synthetase 1
    In: Acta Crystallographica Section D: Structural Biology Vol. 60 (2004) Nr. 2, pp. 350 - 352
    Online Full Text: dx.doi.org/
  • Blankenfeldt, Wulf; Kuzin, Alexandre P.; Skarina, Tatiana; Korniyenko, Yuriy; Tong, Liang; Bayer, Peter; Janning, Petra; Thomashow, Linda S.; Mavrodi, Dmitri V.
    Structure and function of the phenazine biosynthetic protein PhzF from Pseudomonas fluorescens
    In: Proceedings of the National Academy of Sciences of the United States of America Vol. 101 (2004) Nr. 47, pp. 16431 - 16436
    Online Full Text: dx.doi.org/ (Open Access)
  • Reimer, Tatiana; Weiwad, Matthias; Schierhorn, Angelika; Ruecknagel, Peter-Karl; Rahfeld, Jens-Ulrich; Bayer, Peter; Fischer, Gunter.
    Phosphorylation of the N-terminal domain regulates subcellular localization and DNA binding properties of the peptidyl-prolyl cis/trans isomerase hPar14
    In: Journal of Molecular Biology (JMB) Vol. 330 (2003) Nr. 5, pp. 955 - 966
    Online Full Text: dx.doi.org/
  • Bayer, Elena; Goettsch, Sandra; Müller, Jonathan W.; Griewel, Bernhard; Guiberman, Elena; Mayr, Lorenz M.; Bayer, Peter.
    Structural analysis of the mitotic regulator hPin1 in solution : insights into domain architecture and substrate binding
    In: The Journal of Biological Chemistry (JBC) Vol. 278 (2003) Nr. 28, pp. 26183 - 26193
    Online Full Text: dx.doi.org/ (Open Access)
  • Goettsch, S.; Goettsch, W.; Morawietz, H.; Bayer, Peter.
    Induction of tyrosylprotein sulfotransferase isoform shift in human endothelial cells
    In: Circulation Vol. 106 (2002) Nr. Suppl. 2, pp. 287
  • Kalinin, Alexander; Rak, Alexej; Shcherbakov, Dmitry; Bayer, Peter.
    Letter to the Editor: ¹H, ¹³C and ¹⁵N resonance assignments of the ribosome-associated cold shock response protein Yfia of Escherichia coli
    In: Journal of Biomolecular NMR Vol. 23 (2002) Nr. 4, pp. 335 - 336
    Online Full Text: dx.doi.org/
  • Goettsch, Sandra; Goettsch, Winfried; Morawietz, Henning; Bayer, Peter.
    Shear stress mediates tyrosylprotein sulfotransferase isoform shift in human endothelial cells
    In: Biochemical and Biophysical Research Communications (BBRC) Vol. 294 (2002) Nr. 3, pp. 541 - 546
    Online Full Text: dx.doi.org/
  • Rak, Alexey; Kalinin, Alexander; Shcherbakov, Dmitry; Bayer, Peter.
    Solution structure of the ribosome-associated cold shock response protein Yfia of Escherichia coli
    In: Biochemical and Biophysical Research Communications (BBRC) Vol. 299 (2002) Nr. 5, pp. 710 - 714
    Online Full Text: dx.doi.org/
  • Goettsch, S.; Bayer, Peter.
    Structural attributes in the conjugation of Ubiquitin, RUB and SUMO to protein substrates.
    In: Frontiers in Bioscience Vol. 7 (2002) pp. 148 - 162
  • Surmacz, Tatiana Anna; Bayer, Elena; Rahfeld, Jens-Ulrich; Fischer, Gunter; Bayer, Peter.
    The N-terminal basic domain of human parvulin h Par14 is responsible for the entry to the nucleus and high-affinity DNA-binding
    In: Journal of Molecular Biology (JMB) Vol. 321 (2002) Nr. 2, pp. 235 - 247
    Online Full Text: dx.doi.org/
  • Kipping, M.; Zarnt, T.; Kiessig, S.; Reimer, U.; Fischer, G.; Bayer, Peter.
    Increased backbone flexibility in threonine
    In: Biochemistry Vol. 40 (2001) Nr. 27, pp. 7957 - 7963
    Online Full Text: dx.doi.org/
  • Kohlbacher, Oliver; Burchardt, Andreas; Moll, Andreas; Hildebrandt, Andreas; Bayer, Peter; Lenhof, Hans-Peter.
    Structure prediction of protein complexes by an NMR-based protein docking algorithm
    In: Journal of Biomolecular NMR Vol. 20 (2001) Nr. 1, pp. 15 - 21
    Online Full Text: dx.doi.org/
  • Sekerina, E; Rahfeld, J U; Müller, J; Fanghänel, J; Rascher, C; Fischer, G; Bayer, Peter.
    NMR solution structure of hPar14 reveals similarity to the peptidyl prolyl cis/trans isomerase domain of the mitotic regulator hPin1 but indicates a different functionality of the protein
    In: Journal of Molecular Biology (JMB) Vol. 301 (2000) Nr. 4, pp. 1003 - 1017
    Online Full Text: dx.doi.org/
  • Bayer, Peter; Varani, Luca; Varani, Gabriele.
    Nuclear magnetic resonance methods to study RNA-protein complexes
    In: Methods in Enzymology Vol. 317: RNA - Ligand Interactions, Part A (2000) pp. 198 - 220
    Online Full Text: dx.doi.org/
  • Marx, Ute Charlotte; Adermann, Knut; Bayer, Peter; Forssmann, Wolf-Georg; Rösch, Paul.
    Solution structures of human parathyroid hormone fragments hPTH(1-34) and hPTH(1-39) and bovine parathyroid hormone fragment bPTH(1-37)
    In: Biochemical and Biophysical Research Communications (BBRC) Vol. 267 (2000) Nr. 1, pp. 213 - 220
    Online Full Text: dx.doi.org/
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