ZMB Member Astrid Westendorf
ZMB Member
Astrid Westendorf
Next ZMB-Member
Prof. Dr. Astrid Westendorf
Group
Infection ImmunologyInstitute of Medical Microbiology
University Hospital Essen
Hufelandstr. 55
45147 Essen
- +49 201 723 1826
- Website
- Selected Publications
- Publication Metrics
- ZMB Research Program
Immunology, Infectious Diseases and Transplantation
Research Overview
- Role of interleukin-33 during intestinal Citrobacter rodentium infection
- Modulation of the mucosal immune system for the treatment of chronic inflammatory bowel diseases
- Importance of immune cells in the induction and rejection of colitis-mediated colon cancer
- Influence of helminth infection on the course of colitis-related colon cancer
- Role of sphingolipids in inflammatory bowel disease
- Development of new nanoparticle-based strategies for modulating the immune system
Selected Publications
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Barium sulphate microparticles are taken up by three different cell types: HeLa, THP-1, and hMSCIn: Acta Biomaterialia Vol. 164 (2023) pp. 577 - 587Online Full Text: dx.doi.org/
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GPR15 facilitates recruitment of regulatory T cells to promote colorectal cancerIn: Cancer Research Vol. 81 (2021) Nr. 11, pp. 2970 - 2982Online Full Text: dx.doi.org/; Online Full Text: dx.doi.org/ (Open Access)
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Depletion of Foxp3⁺ regulatory T cells is accompanied by an increase in the relative abundance of Firmicutes in the murine gut microbiomeIn: Immunology Vol. 159 (2020) Nr. 3, pp. 344 - 353Online Full Text: dx.doi.org/ (Open Access)
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In vivo biodistribution of calcium phosphate nanoparticles after intravascular, intramuscular, intratumoral, and soft tissue administration in mice investigated by small animal PET/CTIn: Acta Biomaterialia Vol. 109 (2020) pp. 244 - 253Online Full Text: dx.doi.org/
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A network of trans-cortical capillaries as mainstay for blood circulation in long bonesIn: Nature Metabolism Vol. 1 (2019) Nr. 2, pp. 236 - 250Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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A systematic electron microscopic study on the uptake of barium sulphate nano-, submicro-, microparticles by bone marrow-derived phagocytosing cellsIn: Acta Biomaterialia Vol. 80 (2018) pp. 352 - 363Online Full Text: dx.doi.org/
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CEACAM1 promotes CD8⁺ T cell responses and improves control of a chronic viral infectionIn: Nature Communications Vol. 9 (2018) 2561Online Full Text: dx.doi.org/ (Open Access)
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Acquired IFNγ 3 resistance impairs anti-Tumor immunity and gives rise to T-cell-resistant melanoma lesionsIn: Nature Communications Vol. 8 (2017) 15440Online Full Text: dx.doi.org/ (Open Access)
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Avidin-conjugated calcium phosphate nanoparticles as a modular targeting system for the attachment of biotinylated molecules in vitro and in vivoIn: Acta Biomaterialia Vol. 57 (2017) pp. 414 - 425Online Full Text: dx.doi.org/
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Delivery of the TLR ligand poly(I:C) to liver cells in vitro and in vivo by calcium phosphate nanoparticles leads to a pronounced immunostimulationIn: Acta Biomaterialia Vol. 64 (2017) pp. 401 - 410Online Full Text: dx.doi.org/
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Extracellular Adenosine Production by ecto-5'-Nucleotidase (CD73) Enhances Radiation-Induced Lung FibrosisIn: Cancer Research Vol. 76 (2016) Nr. 10, pp. 3045 - 3056Online Full Text: dx.doi.org/ (Open Access)
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Plasmodium yoelii infection of BALB/c mice results in expansion rather than induction of CD4+ Foxp3+ regulatory T cellsIn: Immunology Vol. 148 (2016) Nr. 2, pp. 197 - 205Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Relevance of Foxp3+ regulatory T cells for early and late phases of murine sepsisIn: Immunology Vol. 146 (2015) Nr. 1, pp. 144 - 156Online Full Text: dx.doi.org/ (Open Access)
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Transient ablation of regulatory T cells improves antitumor immunity in colitis-associated colon cancerIn: Cancer Research Vol. 74 (2014) Nr. 16, pp. 4258 - 4269Online Full Text: dx.doi.org/
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Mechanism of the uptake of cationic and anionic calcium phosphate nanoparticles by cellsIn: Acta Biomaterialia Vol. 9 (2013) Nr. 7, pp. 7527 - 7535Online Full Text: dx.doi.org/
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Generation and function of immunosuppressive human and murine CD8⁺ T cells by transforming growth factor-β and retinoic acidIn: Immunology Vol. 134 (2011) Nr. 1, pp. 82 - 92Online Full Text: dx.doi.org/ (Open Access)
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Quantitative determination of the composition of multi-shell calcium phosphate-oligonucleotide nanoparticles and their application for the activation of dendritic cellsIn: Acta Biomaterialia Vol. 7 (2011) Nr. 11, pp. 4029 - 4036Online Full Text: dx.doi.org/
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The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxinsIn: Nature Vol. 453 (2008) Nr. 7191, pp. 106 - 109Online Full Text: dx.doi.org/ Online Full Text (Open Access)