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ZMB Member Ken Herrmann

ZMB Member
Ken Herrmann

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Ken Herrmann portrait
© UDE

Prof. Dr. Ken Herrmann

Group

Clinic for Nuclear Medicine

University Hospital Essen
Hufelandstr. 55
45122 Essen

Research Overview

  • Development, application of new radiopharmaceuticals
  • Diagnosis and therapy of thyroid carcinoma
  • Diagnostics and therapy of endocrine tumors
  • Diagnostics and therapy of prostate cancer
  • Clinical use, optimization of PET, PET / CT

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Press Releases

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uni-due.de | Presse release

Tumorforschung bei Prostatakrebs Neue Bildgebung sagt Behandlungserfolg voraus

[30.10.2024] Ein internationales Konsortium untersucht im Zuge des Projektes ILLUMINATE, wie ein neues bildgebendes Verfahren den Behandlungserfolg für Menschen mit Prostatakrebs in fortgeschrittenem Stadium vorhersagen kann. Im Fokus steht die metabolische Magnetresonanztomographie, die chemische Prozesse im Körper besonders deutlich sichtbar macht. Dem Konsortium gehören Vertreter:innen von 15 Institutionen an, darunter Teams um Prof. Dr. Ken Herrmann und Prof. Dr. Tom Scheenen, Forscher an der Medizinischen Fakultät der Universität Duisburg-Essen. Gefördert wird ILLUMINATE von der „Innovative Health Initiative“ der Europäischen Union (EU IHI) mit rund 19 Millionen Euro, von denen 648.400 Euro nach Essen fließen. Das Projekt startet im November 2024 und läuft 54 Monate.

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Selected Publications

    Journal articles

  • Hricak, Hedvig; Mayerhoefer, Marius E; Herrmann, Ken; Lewis, Jason S; Pomper, Martin G; Hess, Christopher P; Riklund, Katrine; Scott, Andrew M; Weissleder, Ralph.
    Advances and challenges in precision imaging
    In: The Lancet Oncology Vol. 26 (2025) Nr. 1, pp. e34 - e45
    Online Full Text: dx.doi.org/
  • Karpinski, Madeleine J; Hüsing, Johannes; Claassen, Kevin; Möller, Lennart; Kajüter, Hiltraud; Oesterling, Florian; Grünwald, Viktor; Umutlu, Lale; Kleesiek, Jens; Telli, Tugce; Merkel-Jens, Anja; Hüsing, Anika; Kesch, Claudia; Herrmann, Ken; Eiber, Matthi et al.
    Combining PSMA-PET and PROMISE to re-define disease stage and risk in patients with prostate cancer : A multicentre retrospective study
    In: The Lancet Oncology Vol. 25 (2024) Nr. 9, pp. 1188 - 1201
    Online Full Text: dx.doi.org/ (Open Access)
  • Pasquier, David; Bidaut, Luc; Oprea-Lager, Daniela Elena; deSouza, Nandita M; Krug, David; Collette, Laurence; Kunz, Wolfgang; Belkacemi, Yazid; Bau, Maria Grazia; Caramella, Caroline; De Geus-Oei, Lioe-Fee; De Caluwé, Alex; Deroose, Christophe; Gheysens, et al.
    Designing clinical trials based on modern imaging and metastasis-directed treatments in patients with oligometastatic breast cancer : a consensus recommendation from the EORTC Imaging and Breast Cancer Groups
    In: The Lancet Oncology Vol. 24 (2023) Nr. 8, pp. e331 - e343
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Fizazi, Karim; Herrmann, Ken; Krause, Bernd J; Rahbar, Kambiz; Chi, Kim N; Morris, Michael J; Sartor, Oliver; Tagawa, Scott T; Kendi, Ayse T; Vogelzang, Nicholas; Calais, Jeremie; Nagarajah, James; Wei, Xiao X; Koshkin, Vadim S; Beauregard, Jean-Mathieu; C et al.
    Health-related quality of life and pain outcomes with [¹⁷⁷Lu]Lu-PSMA-617 plus standard of care versus standard of care in patients with metastatic castration-resistant prostate cancer (VISION) : a multicentre, open-label, randomised, phase 3 trial
    In: The Lancet Oncology Vol. 24 (2023) Nr. 6, pp. 597 - 610
    Online Full Text: dx.doi.org/
  • Weber, Manuel; Kersting, David; Riemann, Burkhard; Brandenburg, Tim; Führer, Dagmar; Grünwald, Frank; Kreissl, Michael C.; Dralle, Henning; Weber, Frank; Schmid, Kurt Werner; Herrmann, Ken; Jentzen, Walter; Grafe, Hong; Rischpler, Christoph; Theurer, Sarah et al.
    Enhancing Radioiodine Incorporation into Radioiodine-Refractory Thyroid Cancer with MAPK Inhibition (ERRITI) : A Single-Center Prospective Two-Arm Study
    In: Clinical Cancer Research Vol. 28 (2022) Nr. 19, pp. 4194 - 4202
    Online Full Text: dx.doi.org/ (Open Access)
  • Seifert, Robert; Kersting, David; Rischpler, Christoph; Sandach, Patrick; Ferdinandus, Justin; Fendler, Wolfgang; Rahbar, Kambiz; Weckesser, Matthias; Umutlu, Lale; Hanoun, Christine; Hüttmann, Andreas; Reinhardt, Hans Christian; von Tresckow, Bastian; Her et al.
    Interim FDG-PET analysis to identify patients with aggressive non-Hodgkin lymphoma who benefit from treatment intensification : A post-hoc analysis of the PETAL trial
    In: Leukemia Vol. 36 (2022) Nr. 12, pp. 2845 - 2852
    Online Full Text: dx.doi.org/ (Open Access)
  • Bodei, Lisa; Herrmann, Ken; Schöder, Heiko; Scott, Andrew M.; Lewis, Jason S.
    Radiotheranostics in oncology : current challenges and emerging opportunities
    In: Nature Reviews Clinical Oncology Vol. 19 (2022) Nr. 8, pp. 534 - 550
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Fendler, Wolfgang; Pabst, Kim M.; Kessler, Lukas; Fragoso Costa, Pedro; Ferdinandus, Justin; Weber, Manuel; Lippert, Maria; Lückerath, Katharina; Umutlu, Lale; Kostbade, Karina; Mavroeidi, Ilektra A.; Schuler, Martin; Ahrens, Marit; Rischpler, Christoph; B et al.
    Safety and Efficacy of 90Y-FAPI-46 Radioligand Therapy in Patients with Advanced Sarcoma and Other Cancer Entities
    In: Clinical Cancer Research Vol. 28 (2022) Nr. 19, pp. 4346 - 4353
    Online Full Text: dx.doi.org/ (Open Access)
  • Hope, Thomas A.; Eiber, Matthias; Armstrong, Wesley R.; Juarez, Roxanna; Murthy, Vishnu; Lawhn-Heath, Courtney; Behr, Spencer C.; Zhang, Li; Barbato, Francesco; Ceci, Francesco; Farolfi, Andrea; Schwarzenböck, Sarah M.; Unterrainer, Marcus; Zacho, Helle D. et al.
    Diagnostic Accuracy of ⁶⁸Ga-PSMA-11 PET for Pelvic Nodal Metastasis Detection Prior to Radical Prostatectomy and Pelvic Lymph Node Dissection : A Multicenter Prospective Phase 3 Imaging Trial
    In: JAMA Oncology Vol. 7 (2021) Nr. 11, pp. 1635 - 1642
    Online Full Text: dx.doi.org/
  • Gafita, Andrei; Calais, Jeremie; Grogan, Tristan R.; Hadaschik, Boris; Wang, Hui; Weber, Manuel; Sandhu, Shahneen; Kratochwil, Clemens; Esfandiari, Rouzbeh; Tauber, Robert; Zeldin, Anna; Rathke, Hendrik; Armstrong, Wesley R.; Robertson, Andrew; Thin, Pan; et al.
    Nomograms to predict outcomes after ¹⁷⁷Lu-PSMA therapy in men with metastatic castration-resistant prostate cancer : An international, multicentre, retrospective study
    In: The Lancet Oncology Vol. 22 (2021) Nr. 8, pp. 1115 - 1125
    Online Full Text: dx.doi.org/ (Open Access)
  • Herrmann, Ken; Kraus, Bernd Joachim; Hadaschik, Boris; Kunikowska, Jolanta; van Poppel, Hendrik; N'Dow, James; Sartor, Oliver; Oyen, Wim J. G.
    Nuclear medicine theranostics comes of age
    In: The Lancet Oncology Vol. 22 (2021) Nr. 11, pp. 1497 - 1498
    Online Full Text: dx.doi.org/
  • Kollenda, Sebastian; Klose, Jasmin; Knuschke, Torben; Sokolova, Viktoriya; Schmitz, Jochen; Staniszewska, Magdalena; Costa, Pedro Fragoso; Herrmann, Ken; Westendorf, Astrid; Fendler, Wolfgang; Epple, Matthias.
    In vivo biodistribution of calcium phosphate nanoparticles after intravascular, intramuscular, intratumoral, and soft tissue administration in mice investigated by small animal PET/CT
    In: Acta Biomaterialia Vol. 109 (2020) pp. 244 - 253
    Online Full Text: dx.doi.org/
  • Bodei, Lisa; Schöder, Heiko; Baum, Richard P; Herrmann, Ken; Strosberg, Jonathan; Caplin, Martyn; Öberg, Kjell; Modlin, Irvin M.
    Molecular profiling of neuroendocrine tumours to predict response and toxicity to peptide receptor radionuclide therapy
    In: The Lancet Oncology Vol. 21 (2020) Nr. 9, pp. e431 - e443
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Herrmann, Ken; Schwaiger, Markus; Lewis, Jason S.; Solomon, Stephen B.; McNeil, Barbara J.; Baumann, Michael; Gambhir, Sanjiv S.; Hricak, Hedvig; Weissleder, Ralph.
    Radiotheranostics : A roadmap for future development
    In: The Lancet Oncology Vol. 21 (2020) Nr. 3, pp. e146 - e156
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Fendler, Wolfgang P.; Calais, Jeremie; Eiber, Matthias; Flavell, Robert R.; Mishoe, Ashley; Feng, Felix Y.; Nguyen, Hao G.; Reiter, Robert E.; Rettig, Matthew B.; Okamoto, Shozo; Emmett, Louise; Zacho, Helle D.; Ilhan, Harun; Wetter, Axel; Rischpler, Chris et al.
    Assessment of ⁶⁸Ga-PSMA-11 PET Accuracy in Localizing Recurrent Prostate Cancer : A Prospective Single-Arm Clinical Trial
    In: JAMA Oncology Vol. 5 (2019) Nr. 6, pp. 856 - 863
    Online Full Text: dx.doi.org/ (Open Access)
  • Schotten, Clemens; Bechmann, Lars Peter; Manka, Paul; Theysohn, Jens; Dechene, Alexander; El Fouly, Amr; Barbato, Francesco; Neumann, Ursula; Radünz, Sonia; Sydor, Svenja; Heider, Dominik; Venerito, Marino; Canbay, Aliekber; Gerken, Guido; Herrmann, Ken; W et al.
    NAFLD-Associated Comorbidities in Advanced Stage HCC Do Not Alter the Safety and Efficacy of Yttrium-90 Radioembolization
    In: Liver Cancer Vol. 8 (2019) Nr. 6, pp. 491 - 504
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Fendler, Wolfgang P.; Weber, Manuel; Iravani, Amir; Hofman, Michael S.; Calais, Jeremie; Czernin, Johannes; Ilhan, Harun; Saad, Fred; Small, Eric J.; Smith, Matthew R.; Perez, Paola M.; Hope, Thomas A.; Rauscher, Isabel; Londhe, Anil; Lopez-Gitlitz, Angela et al.
    Prostate-specific membrane antigen ligand positron emission tomography in men with nonmetastatic castration-resistant prostate cancer
    In: Clinical Cancer Research Vol. 25 (2019) Nr. 24, pp. 7448 - 7454
    Online Full Text: dx.doi.org/ (Open Access)
  • Gerwing, Mirjam; Herrmann, Ken; Helfen, Anne; Schliemann, Christoph; Berdel, Wolfgang E.; Eisenblätter, Michel; Wildgruber, Moritz.
    The beginning of the end for conventional RECIST — novel therapies require novel imaging approaches
    In: Nature Reviews Clinical Oncology Vol. 16 (2019) Nr. 7, pp. 442 - 458
    Online Full Text: dx.doi.org/
  • Fanti, Stefano; Minozzi, Silvia; Antoch, Gerald; Banks, Ian; Briganti, Alberto; Carrio, Ignasi; Chiti, Arturo; Clarke, Noel; Eiber, Matthias; De Bono, Johann; Fizazi, Karim; Gillessen, Silke; Gledhill, Sam; Haberkorn, Uwe; Herrmann, Ken; Hicks, Rodney J.; et al.
    Consensus on molecular imaging and theranostics in prostate cancer
    In: The Lancet Oncology Vol. 19 (2018) Nr. 12, pp. e696 - e708
    Online Full Text: dx.doi.org/
  • Schotten, C.; Bechmann, Lars Peter; Manka, Paul; Theysohn, Jens; Dechene, Alexander; El Fouly, A.; Muller, S.; Schulze, Maren; Neumann, U.; Radunz, S.; Heider, Dominik; Canbay, Aliekber; Gerken, Guido; Herrmann, Ken; Wedemeyer, Heiner; Best, Jan.
    Extrahepatic Comorbidities Do Not Alter the Safety and Efficacy of Radioembolization of NAFLD-Associated HCC
    In: Hepatology Vol. 68 (2018) Nr. Suppl. 1, pp. 852A - 853A
  • Lecouvet, Frédéric E.; Oprea-Lager, Daniela E.; Liu, Yan; Ost, Piet; Bidaut, Luc; Collette, Laurence; Deroose, Christophe M.; Goffin, Karolien; Herrmann, Ken; Hoekstra, Otto S.; Kramer, Gem; Lievens, Yolande; Lopci, Egesta; Pasquier, David; Petersen, Lars et al.
    Use of modern imaging methods to facilitate trials of metastasis-directed therapy for oligometastatic disease in prostate cancer : a consensus recommendation from the EORTC Imaging Group
    In: The Lancet Oncology Vol. 19 (2018) Nr. 10, pp. e534 - e545
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Caldarelli, Antonio; Müller, Jörg P.; Paskowski-Rogacz, M.; Herrmann, Ken; Bauer, Reinhard F.; Koch, Sina; Heninger, Anne Kristin; Krastev, Dragomir Blazhev; Ding, Li; Kasper, Stefan; Fischer, Thomas A.; Brodhun, Michael; Böhmer, Frank Dietmar; Buchholz, F et al.
    A genome-wide RNAi screen identifies proteins modulating aberrant FLT3-ITD signaling
    In: Leukemia Vol. 27 (2013) Nr. 12, pp. 2301 - 2310
    Online Full Text: dx.doi.org/
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