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ZMB Member Anke Hinney

ZMB Member
Anke Hinney

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Anke Hinney portrait
© UDE

Prof. Dr. Anke Hinney

Group

Clinic for Psychiatry, Psychosomatics and Psychotherapy of Children and Adolescents

Wickenburgstraße 21
45147 Essen

Research Overview

Molecular genetic investigations of

  • early-onset obesity
  • eating disorders
  • attention deficit hyperactivity disorder (ADHD)

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Selected Publications

    Journal articles

  • Käver, Larissa; Hinney, Anke; Rajcsanyi, Luisa Sophie; Maier, Hannah Benedictine; Frieling, Helge; Steiger, Howard; Voelz, Clara; Beyer, Cordian; Trinh, Stefanie; Seitz, Jochen.
    Epigenetic alterations in patients with anorexia nervosa : A systematic review
    In: Molecular Psychiatry Vol. 29 (2024) Nr. 12, pp. 3900 - 3914
    Online Full Text: dx.doi.org/ (Open Access)
  • Giuranna, Johanna; Zheng, Yiran; Brandt, Matthäus; Jall, Sigrid; Mukherjee, Amrita; Shankhwar, Soni; Renner, Simone; Kurapati, Nirup Kumar; May, Caroline; Peters, Triinu; Herpertz-Dahlmann, Beate; Seitz, Jochen; de Zwaan, Martina; Herzog, Wolfgang; Ehrlich et al.
    Genetic and functional analyses of CTBP2 in anorexia nervosa and body weight regulation
    In: Molecular Psychiatry (2024) in press
    Online Full Text: dx.doi.org/ (Open Access)
  • Berger, Marc; Brenner, Thorsten; Hinney, Anke; Witzke, Oliver; Konik, Margarethe; The COVID-19 Host Genetics Initiative.
    A second update on mapping the human genetic architecture of COVID-19
    In: Nature Vol. 621 (2023) pp. E7 - E26
    Online Full Text: dx.doi.org/ (Open Access)
  • Berger, Marc; Brenner, Thorsten; Hinney, Anke; Witzke, Oliver.
    Mapping the human genetic architecture of COVID-19
    In: Nature Vol. 600 (2021) pp. 472 - 477
    Online Full Text: dx.doi.org/ (Open Access)
  • Watson, Hunna J.; Hinney, Anke; Giuranna, Johanna; Hebebrand, Johannes.
    Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa
    In: Nature Genetics Vol. 51 (2019) Nr. 8, pp. 1207 - 1214
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Huckins, L.M.; Hatzikotoulas, K.; Southam, L.; Thornton, L.M.; Steinberg, J.; Aguilera-McKay, F.; Treasure, J.; Schmidt, U.; Gunasinghe, C.; Romero, A.; Curtis, C.; Rhodes, D.; Moens, J.; Kalsi, G.; Dempster, D.; Leung, R.; Keohane, A.; Burghardt, R.; Ehrl et al.
    Correction: Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa
    In: Molecular Psychiatry Vol. 23 (2018) Nr. 9, pp. 1
    Online Full Text: dx.doi.org/ (Open Access)
  • Huckins, L.M.; Hatzikotoulas, K.; Southam, L.; Thornton, L.M.; Steinberg, J.; Aguilera-Mckay, F.; Treasure, J.; Schmidt, U.; Gunasinghe, C.; Romero, A.; Curtis, C.; Rhodes, D.; Moens, J.; Kalsi, G.; Dempster, D.; Leung, R.; Keohane, A.; Burghardt, R.; Ehrl et al.
    Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa
    In: Molecular Psychiatry Vol. 23 (2018) Nr. 5, pp. 1169 - 1180
    Online Full Text: dx.doi.org/ (Open Access)
  • Hinney, Anke; Kesselmeier, Miriam; Jall, Sigrid; Volckmar, Anna Lena; Föcker, Manuel; Antel, Jochen; Heid, Iris M.; Winkler, Thomas W.; Grant, Struan F. A.; Guo, Y.; Bergen, Andrew W.; Kaye, Walter H.; Berrettini, W. H.; Hakonarson, Hakon; Herpertz-Dahlman et al.
    Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index
    In: Molecular Psychiatry Vol. 22 (2017) pp. 192 - 201
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Kühnen, Peter; Handke, Daniela; Waterland, Robert A; Hennig, Branwen J; Silver, Matt; Fulford, Anthony J; Dominguez-Salas, Paula; Moore, Sophie E; Prentice, Andrew M; Spranger, Joachim; Hinney, Anke; Hebebrand, Johannes; Heppner, Frank L; Walzer, Lena; Grö et al.
    Interindividual Variation in DNA Methylation at a Putative POMC Metastable Epiallele Is Associated with Obesity
    In: Cell Metabolism Vol. 24 (2016) Nr. 3, pp. 502 - 509
    Online Full Text: dx.doi.org/ (Open Access)
  • Boraska, V; Franklin, C S; Floyd, J A B; Thornton, L M; Huckins, L M; Southam, L; Rayner, N W; Tachmazidou, I; Klump, K L; Treasure, J; Lewis, C M; Schmidt, U; Tozzi, F; Kiezebrink, K; Hebebrand, Johannes; Gorwood, P; Adan, R A H; Kas, M J H; Favaro, A; Sa et al.
    A genome-wide association study of anorexia nervosa
    In: Molecular Psychiatry Vol. 19 (2014) Nr. 10, pp. 1085 - 1094
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Jarick, I.; Volckmar, A.-L.; Pütter, Carolin; Pechlivanis, Sonali; Nguyen. T. T.; Dauvermann, R.; Beck, S.; Albayrak, Özgür; Scherag, S.; Gilsbach, S.; Cichon, S.; Hoffmann, P.; Degenhardt, F.; Nöthen, M. M.; Schreiber, S.; Wichmann, H.-E.; Jöckel, Karl-He et al.
    Genome-wide analysis of rare copy number variations reveals PARK2 as a candidate gene for attention-deficit/hyperactivity disorder
    In: Molecular Psychiatry Vol. 19 (2014) Nr. 1, pp. 115 - 121
    Online Full Text: dx.doi.org/ (Open Access)
  • Berndt, Sonja; Gustafsson, Stefan; Magi, Reedik; Ganna, Andrea; Wheeler, Eleanor; Feitosa, Mary; Justice, Anne; Monda, Keri; Croteau-Chonka, Damien; Day, Felix; Pechlivanis, Sonali; Hebebrand, Johannes; Pütter, Carolin; Hinney, Anke; Jöckel, Karl-Heinz; Sc et al.
    Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
    In: Nature Genetics Vol. 45 (2013) Nr. 5, pp. 501 - 512
    Online Full Text: dx.doi.org/
  • Bradfield, Jonathan P.; Taal, H. Rob; Timpson, Nicholas J.; Scherag, Andre; Lecoeur, Cecile; Warrington, Nicole M.; Hypponen, Elina; Holst, Claus; Valcarcel, Beatriz; Thiering, Elisabeth; Salem, Rany M.; Schumacher, Fredrick R.; Cousminer, Diana L.; Sleima et al.
    A genome-wide association meta-analysis identifies new childhood obesity loci
    In: Nature Genetics Vol. 44 (2012) Nr. 5, pp. 526 - 531
    Online Full Text: dx.doi.org/
  • Rob Taal, H.; St Pourcain, Beate; Thiering, Elisabeth; Das, Shikta; Mook-Kanamori, Dennis O.; Warrington, Nicole M.; Kaakinen, Marika; Kreiner-Møller, Eskil; Bradfield, Jonathan P.; Freathy, Rachel M.; Geller, Frank; Guxens, Mònica; Cousminer, Diana L.; Ke et al.
    Common variants at 12q15 and 12q24 are associated with infant head circumference
    In: Nature Genetics Vol. 44 (2012) Nr. 5, pp. 532 - 538
    Online Full Text: dx.doi.org/
  • Ikram, M. Arfan; Fornage, Myriam; Smith, Albert V.; Seshadri, Sudha; Schmidt, Reinhold; Debette, Stéphanie; Vrooman, Henri A.; Sigurdsson, Sigurdur; Ropele, Stefan; Taal, H. Rob; Mook-Kanamori, Dennis O.; Coker, Laura H.; Longstreth, W.T.; Niessen, Wiro J. et al.
    Common variants at 6q22 and 17q21 are associated with intracranial volume
    In: Nature Genetics Vol. 44 (2012) Nr. 5, pp. 539 - 544
    Online Full Text: dx.doi.org/
  • Ichimura, Atsuhiko; Hirasawa, Akira; Poulain-Godefroy, Odile; Bonnefond, Amélie; Hara, Takafumi; Yengo, Loïc; Kimura, Ikuo; Leloire, Audrey; Liu, Ning; Iida, Keiko; Choquet, Hélène; Besnard, Philippe; Lecoeur, Cécile; Vivequin, Sidonie; Ayukawa, Kumiko; Ta et al.
    Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human
    In: Nature Vol. 483 (2012) Nr. 7389, pp. 350 - 354
    Online Full Text: dx.doi.org/
  • Wojciechowski, P.; Lipowska, A.; Rys, P.; Ewens, K. G.; Franks, S.; Tan, Susanne; Lerchbaum, E.; Vcelak, J.; Attaoua, R.; Straczkowski, M.; Azziz, R.; Barber, T. M.; Hinney, Anke; Obermayer-Pietsch, B.; Lukasova, P.; Bendlova, B.; Grigorescu, F.; Kowalska, et al.
    Erratum to: Impact of FTO genotypes on BMI and weight in polycystic ovary syndrome : a systematic review and meta-analysis
    In: Diabetologia Vol. 55 (2012) Nr. 10, pp. 2858 - 2859
    Online Full Text: dx.doi.org/
  • Wojciechowski, Piotr; Lipowska, Anna M.; Rys, Przemysław M.; Ewens, Kathryn G.; Franks, Stephen J.; Tan, Susanne; Lerchbaum, Elisabeth; Vcelak, Josef; Attaoua, Redha; Straczkowski, Marek; Azziz, Ricardo; Barber, Thomas M.; Hinney, Anke; Obermayer-Pietsch, et al.
    Impact of FTO genotypes on BMI and weight in polycystic ovary syndrome : A systematic review and meta-analysis
    In: Diabetologia Vol. 55 (2012) Nr. 10, pp. 2636 - 2645
    Online Full Text: dx.doi.org/ (Open Access)
  • Scherag, Andre; Boes, Tanja; Hinney, Anke; Scherag, Susann; Vogel, Carla I.; Hebebrand, Johannes.
    Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
    In: Nature Genetics Vol. 42 (2010) Nr. 11, pp. 937 - 948
    Online Full Text: dx.doi.org/
  • Speliotes, Elizabeth K.; Willer, Cristen J.; Berndt, Sonja I.; Monda, Keri L.; Thorleifsson, Gudmar; Jackson, Anne U.; Allen, Hana Lango; Lindgren, Cecilia M.; Luan, Jian'an; Mägi, Reedik; Randall, Joshua C.; Vedantam, Sailaja; Winkler, Thomas W.; Qi, Lu; et al.
    Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
    In: Nature Genetics Vol. 42 (2010) Nr. 11, pp. 937 - 948
    Online Full Text: dx.doi.org/ (Open Access)
  • Le Hellard, S.; Theisen, F.M.; Haberhausen, M.; Raeder, M.B.; Fernø, J.; Gebhardt, S.; Hinney, Anke; Remschmidt, H.; Krieg, J.C.; Mehler-Wex, C.; Nöthen, M.M.; Hebebrand, Johannes; Steen, V.M.
    Association between the insulin-induced gene 2 (INSIG2) and weight gain in a German sample of antipsychotic-treated schizophrenic patients : Perturbation of SREBP-controlled lipogenesis in drug-related metabolic adverse effects?
    In: Molecular Psychiatry Vol. 14 (2009) Nr. 3, pp. 308 - 317
    Online Full Text: dx.doi.org/ (Open Access)
  • Loos, Ruth J. F.; Lindgren, Cecilia M; Li, Shengxu; Wheeler, Eleanor; Hua Zhao, Jing; Prokopenko, Inga; Inouye, Michael; Freathy, Rachel M; Attwood, Antony P; Beckmann, Jacques S; Berndt, Sonja I; Bergmann, Sven; Bennett, Amanda J; Bingham, Sheila A; Bochu et al.
    Common variants near MC4R are associated with fat mass, weight and risk of obesity
    In: Nature Genetics Vol. 40 (2008) Nr. 6, pp. 768 - 775
    Online Full Text: dx.doi.org/
  • Friedel, S.; Saar, K.; Sauer, S.; Dempfle, A.; Walitza, S.; Renner, T.; Romanos, M.; Freitag, C.; Seitz, C.; Palmason, H.; Scherag, A.; Windemuth-Kieselbach, C.; von Schimmelmann, Benno; Wewetzer, C.; Meyer, J.; Warnke, A.; Lesch, K.P.; Reinhardt, R.; Herp et al.
    Association and linkage of allelic variants of the dopamine transporter gene in ADHD
    In: Molecular Psychiatry Vol. 12 (2007) Nr. 10, pp. 923 - 933
    Online Full Text: dx.doi.org/ (Open Access)
  • Helgason, Agnar; Pálsson, Snæbjörn; Thorleifsson, Gudmar; Grant, Struan F. A.; Emilsson, Valur; Gunnarsdottir, Steinunn; Adeyemo, Adebowale; Chen, Yuanxiu; Chen, Guanjie; Reynisdottir, Inga; Benediktsson, Rafn; Hinney, Anke; Hansen, Torben; Andersen, Gitte et al.
    Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution
    In: Nature Genetics Vol. 39 (2007) Nr. 2, pp. 218 - 225
    Online Full Text: dx.doi.org/
  • Hebebrand, Johannes; Dempfle, A.; Saar, K.; Thiele, H.; Herpertz-Dahlmann, B.; Linder, M.; Kiefl, H.; Remschmidt, H.; Hemminger, U.; Warnke, A.; Knölker, U.; Heiser, P.; Friedel, S.; Hinney, Anke; Schäfer, H.; Nürnberg, P.; Konrad, K.
    A genome-wide scan for attention-deficit/hyperactivity disorder in 155 German sib-pairs
    In: Molecular Psychiatry Vol. 11 (2006) Nr. 2, pp. 196 - 205
    Online Full Text: dx.doi.org/ (Open Access)
  • Biebermann, Heike; Castañeda, Tamara R.; van Landeghem, Frank; von Deimling, Andreas; Escher, Frederike; Brabant, Georg; Hebebrand, Johannes; Hinney, Anke; Tschöp, Matthias H.; Grüters, Annette; Krude, Heiko.
    A role for β-melanocyte-stimulating hormone in human body-weight regulation
    In: Cell Metabolism Vol. 3 (2006) Nr. 2, pp. 141 - 146
    Online Full Text: dx.doi.org/ (Open Access)
  • Hebebrand, Johannes; Geller, F.; Dempfle, A.; Heinzel-Gutenbrunner, M.; Raab, M.; Gerber, G.; Wermter, A.-K.; Horro, F.F.; Blundell, J.; Schäfer, H.; Remschmidt, H.; Herpertz, S.; Hinney, Anke.
    Binge-eating episodes are not characteristic of carriers of melanocortin-4 receptor gene mutations
    In: Molecular Psychiatry Vol. 9 (2004) Nr. 8, pp. 796 - 800
    Online Full Text: dx.doi.org/ (Open Access)
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