ZMB Member Alpaslan Tasdogan

ZMB Member
Alpaslan Tasdogan

Next ZMB-Member
Alpaslan Tasdogan portrait
© Dave Kittel/UK Essen

Prof. Dr. Dr. Alpaslan Tasdogan

Group

Tumor Metabolism

Clinic for Dermatology
University Hospital Essen
Hufelandstraße 55
45147 Essen

Research Overview

  1. Better understanding the molecular regulators of cancer metastasis
  2. Developing novel metabolic tools to study cancer metabolism in vivo
  3. Applying state-of-the art metabolic technologies to study melanoma metabolism in patient
  4. Discovering new metabolic vulnerabilities in melanoma metastasis

Publications

    Journal articles

  • Krueger, Oskar; Eisenburger, Robin; Tasdogan, Alpaslan; Zimmer, Lisa; Livingstone, Elisabeth; Hadaschik, Eva; Theurer, Sarah; Brodin, Berthold; Schadendorf, Dirk; Ugurel, Selma
    Case report: : Durable complete response of a mucosal melanoma of the rectum after neoadjuvant immunotherapy with ipilimumab plus nivolumab
    In: Frontiers in Immunology Vol. 15 (2024) 1369190
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Krefting, Frederik; Moelleken, Maurice; Hölsken, Stefanie; Placke, Jan-Malte; Eisenburger, Robin Tamara; Albrecht, Jessica Lea; Tasdogan, Alpaslan; Schadendorf, Dirk; Ugurel, Selma; Dissemond, Joachim; Sondermann, Wiebke
    Comparison of visual diagnostic accuracy of dermatologists practicing in Germany in patients with light skin and skin of color
    In: Scientific Reports Vol. 14 (2024) Nr. 1, 8740
    Online Full Text: dx.doi.org/ (Open Access)
  • Dobersalske, Celia; Rauschenbach, Laurèl; Hua, Yichao; Berliner, Christoph; Steinbach, Anita; Grüneboom, Anika; Kokkaliaris, Konstantinos D.; Heiland, Dieter H.; Berger, Pia; Langer, Sarah; Tan, Chin L.; Stenzel, Martin; Landolsi, Somaya; Weber, Flora; Darkwah Oppong, Marvin; Werner, Rudolf A.; Gull, Hanah; Schröder, Thomas; Linsenmann, Thomas; Buck, Andreas K.; Gunzer, Matthias; Stuschke, Martin; Keyvani, Kathy; Forsting, Michael; Glas, Martin; Kipnis, Jonathan; Steindler, Dennis A.; Reinhardt, Hans Christian; Green, Edward W.; Platten, Michael; Tasdogan, Alpaslan; Herrmann, Ken; Rambow, Florian; Cima, Igor; Sure, Ulrich; Scheffler, Björn
    Cranioencephalic functional lymphoid units in glioblastoma
    In: Nature Medicine (2024) in press
    Online Full Text: dx.doi.org/ (Open Access)
  • Tran, Diem H.; Kim, Dohun; Kesavan, Rushendhiran; Brown, Harrison; Dey, Trishna; Soflaee, Mona Hoseini; Vu, Hieu S.; Tasdogan, Alpaslan; Guo, Jason; Bezwada, Divya; Al Saad, Houssam; Cai, Feng; Solmonson, Ashley; Rion, Halie; Chabatya, Rawand; Merchant, Salma; Manales, Nathan J.; Tcheuyap, Vanina T.; Mulkey, Megan; Mathews, Thomas P.; Brugarolas, James; Morrison, Sean J.; Zhu, Hao; DeBerardinis, Ralph J.; Hoxhaj, Gerta
    De novo and salvage purine synthesis pathways across tissues and tumors
    In: Cell Vol. 187 (2024) Nr. 14, pp. 3602 - 3618.e20
    Online Full Text: dx.doi.org/
  • Leven, Anna-Sophia; Eisenburger, Robin Tamara; Espelage, Lena; Tasdogan, Alpaslan
    Diätetische Ansätze in der Tumortherapie
    In: TumorDiagnostik & Therapie Vol. 45 (2024) Nr. 3, pp. 186 - 194
    Online Full Text: dx.doi.org/
  • Lodde, Georg; Zhao, Fang; Herbst, Rudolf; Terheyden, Patrick; Utikal, Jochen; Pföhler, Claudia; Ulrich, Jens; Kreuter, Alexander; Mohr, Peter; Gutzmer, Ralf; Meier, Friedegund; Dippel, Edgar; Weichenthal, Michael; Jansen, Philipp; Kowall, Bernd; Galetzka, Wolfgang; Hörst, Fabian; Kleesiek, Jens; Hellwig, Birte; Rahnenführer, Jörg; Rajcsanyi, Luisa; Peters, Triinu; Hinney, Anke; Placke, Jan-Malte; Sucker, Antje; Paschen, Annette; Becker, Jürgen; Livingstone, Elisabeth; Zimmer, Lisa; Tasdogan, Alpaslan; Rösch, Alexander; Hadaschik, Eva; Schadendorf, Dirk; Griewank, Klaus; Ugurel, Selma
    Early versus late response to PD-1-based immunotherapy in metastatic melanoma
    In: European Journal of Cancer (EJC) Vol. 210 (2024) 114295
    Online Full Text: dx.doi.org/ (Open Access)
  • Rogava, Meri; Aprati, Tyler J.; Chi, Wei-Yu; Melms, Johannes C.; Hug, Clemens; Davis, Stephanie H.; Earlie, Ethan M.; Chung, Charlie; Deshmukh, Sachin K.; Wu, Sharon; Sledge, George; Tang, Stephen; Ho, Patricia; Amin, Amit Dipak; Caprio, Lindsay; Gurjao, Carino; Tagore, Somnath; Ngo, Bryan; Lee, Michael J.; Zanetti, Giorgia; Wang, Yiping; Chen, Sean; Ge, William; Melo, Luiza Martins Nascentes; Allies, Gabriele; Rösler, Jonas; Gibney, Goeffrey T.; Schmitz, Oliver J.; Sykes, Megan; Creusot, Rémi J.; Tüting, Thomas; Schadendorf, Dirk; Röcken, Martin; Eigentler, Thomas K.; Molotkov, Andrei; Mintz, Akiva; Bakhoum, Samuel F.; Beyaz, Semir; Cantley, Lewis C.; Sorger, Peter K.; Meckelmann, Sven; Tasdogan, Alpaslan; Liu, David; Laughney, Ashley M.; Izar, Benjamin
    Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation
    In: Nature Cancer Vol. 5 (2024) Nr. 3, pp. 433 - 447
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Tasdogan, Alpaslan; Dissemond, Joachim
    Multilokuläres Pyoderma gangraenosum durch Levamisol-gestrecktes Kokain
    In: Die Dermatologie Vol. 75 (2024) Nr. 8, pp. 640
    Online Full Text: dx.doi.org/ (Open Access)
  • Shelton, Spencer D.; House, Sara; Martins Nascentes Melo, Luiza; Ramesh, Vijayashree; Chen, Zhenkang; Wei, Tao; Wang, Xun; Llamas, Claire B.; Venigalla, Siva Sai Krishna; Menezes, Cameron J.; Allies, Gabriele; Krystkiewicz, Jonathan; Rösler, Jonas; Meckelmann, Sven W.; Zhao, Peihua; Rambow, Florian; Schadendorf, Dirk; Zhao, Zhiyu; Gill, Jennifer G.; DeBerardinis, Ralph J.; Morrison, Sean J.; Tasdogan, Alpaslan; Mishra, Prashant
    Pathogenic mitochondrial DNA mutations inhibit melanoma metastasis
    In: Science Advances Vol. 10 (2024) Nr. 44, eadk8801
    Online Full Text: dx.doi.org/ (Open Access)
  • Phan, Julia; Chen, Brandon; Zhao, Zhiyu; Allies, Gabriele; Iannaccone, Antonella; Paul, Animesh; Cansiz, Feyza; Spina, Alberto; Leven, Anna-Sophia; Gellhaus, Alexandra; Schadendorf, Dirk; Kimmig, Rainer; Mettlen, Marcel; Tasdogan, Alpaslan; Morrison, Sean J.
    Retrotransposons are co-opted to activate hematopoietic stem cells and erythropoiesis
    In: Science Vol. 386 (2024) Nr. 6722, pp. eado6836
    Online Full Text: dx.doi.org/
  • Imada, Shinya; Khawaled, Saleh; Shin, Heaji; Meckelmann, Sven W.; Whittaker, Charles A.; Corrêa, Renan Oliveira; Alquati, Chiara; Lu, Yixin; Tie, Guodong; Pradhan, Dikshant; Calibasi-Kocal, Gizem; Nascentes Melo, Luiza Martins; Allies, Gabriele; Rösler, Jonas; Wittenhofer, Pia; Krystkiewicz, Jonathan; Schmitz, Oliver J.; Roper, Jatin; Vinolo, Marco Aurelio Ramirez; Ricciardiello, Luigi; Lien, Evan C.; Vander Heiden, Matthew G.; Shivdasani, Ramesh A.; Cheng, Chia-Wei; Tasdogan, Alpaslan; Yilmaz, Ömer H.
    Short-term post-fast refeeding enhances intestinal stemness via polyamines
    In: Nature (2024) in press
    Online Full Text: dx.doi.org/
  • Espelage, Lena; Wagner, Natalie; Placke, Jan-Malte; Ugurel, Selma; Tasdogan, Alpaslan
    The Interplay between Metabolic Adaptations and Diet in Cancer Immunotherapy
    In: Clinical Cancer Research Vol. 30 (2024) Nr. 15, pp. 3117 - 3127
    Online Full Text: dx.doi.org/
  • Nascentes Melo, Luiza Martins; Kumar, Suresh; Riess, Valeria; Szylo, Krystina J.; Eisenburger, Robin; Schadendorf, Dirk; Ubellacker, Jessalyn M.; Tasdogan, Alpaslan
    Advancements in melanoma cancer metastasis models
    In: Pigment Cell and Melanoma Research Vol. 36 (2023) Nr. 2, pp. 206 - 223
    Online Full Text: dx.doi.org/ (Open Access)
  • Lodde, Georg C.; Jansen, Philipp; Herbst, Rudolf; Terheyden, Patrick; Utikal, Jochen; Pföhler, Claudia; Ulrich, Jens; Kreuter, Alexander; Mohr, Peter; Gutzmer, Ralf; Meier, Friedegund; Dippel, Edgar; Weichenthal, Michael; Sucker, Antje; Placke, Jan-Malte; Zaremba, Anne; Albrecht, Lea Jessica; Kowall, Bernd; Galetzka, Wolfgang; Becker, Jürgen C.; Tasdogan, Alpaslan; Zimmer, Lisa; Livingstone, Elisabeth; Hadaschik, Eva; Schadendorf, Dirk; Ugurel, Selma; Griewank, Klaus
    Characterisation and outcome of RAC1 mutated melanoma
    In: European Journal of Cancer (EJC) Vol. 183 (2023) pp. 1 - 10
    Online Full Text: dx.doi.org/
  • Leven, Anna-Sophia; Becker, Jürgen C.; Pöttgen, Christoph; Schadendorf, Dirk; Ugurel, Selma; Tasdogan, Alpaslan
    Combined immunotherapy with ipilimumab plus nivolumab in metastatic PD-1/PD-L1-refractory Merkel cell carcinoma : a case report
    In: International Journal of Dermatology Vol. 63 (2023) Nr. 2, pp. e69 - e71
    Online Full Text: dx.doi.org/
  • Placke, Jan-Malte; Kimmig, Mona; Griewank, Klaus; Herbst, Rudolf; Terheyden, Patrick; Utikal, Jochen; Pföhler, Claudia; Ulrich, Jens; Kreuter, Alexander; Mohr, Peter; Gutzmer, Ralf; Meier, Friedegund; Dippel, Edgar; Welzel, Julia; Engel, Daniel Robert; Kreft, Sophia; Sucker, Antje; Lodde, Georg; Krefting, Frederik; Stoffels, Ingo; Klode, Joachim; Rösch, Alexander; Zimmer, Lisa; Livingstone, Elisabeth; Hadaschik, Eva; Becker, Jürgen; Weichenthal, Michael; Tasdogan, Alpaslan; Schadendorf, Dirk; Ugurel, Selma
    Correlation of tumor PD-L1 expression in different tissue types and outcome of PD-1-based immunotherapy in metastatic melanoma ADOREG/TRIM : Analysis of the DeCOG prospective multicenter cohort study
    In: EBioMedicine Vol. 96 (2023) 104774
    Online Full Text: dx.doi.org/ (Open Access)
  • Leven, Anna-Sophia; Eisenburger, Robin Tamara; Espelage, Lena; Tasdogan, Alpaslan
    Diätetische Ansätze in der Tumortherapie
    In: Aktuelle Dermatologie Vol. 49 (2023) Nr. 12, pp. 556 - 564
    Online Full Text: dx.doi.org/
  • Tasdogan, Alpaslan; Moelleken, Maurice; Dissemond, Joachim
    Ekzeme der Wundumgebung : Genese, Diagnostik und Therapie
    In: Zeitschrift für Gerontologie und Geriatrie Vol. 56 (2023) Nr. 6, pp. 505 - 515
    Online Full Text: dx.doi.org/
  • Gao, Xiang; Murphy, Malea M.; Peyer, James G.; Ni, Yuehan; Yang, Min; Zhang, Yixuan; Guo, Jiaming; Kara, Nergis; Embree, Claire; Tasdogan, Alpaslan; Ubellacker, Jessalyn M.; Crane, Genevieve M.; Fang, Shentong; Zhao, Zhiyu; Shen, Bo; Morrison, Sean J.
    Leptin receptor⁺ cells promote bone marrow innervation and regeneration by synthesizing nerve growth factor
    In: Nature Cell Biology Vol. 25 (2023) Nr. 12, pp. 1746 - 1757
    Online Full Text: dx.doi.org/ (Open Access)
  • Solari, Fiorella A.; Krahn, Daniel; Swieringa, Frauke; Verhelst, Steven; Rassaf, Tienush; Tasdogan, Alpaslan; Zahedi, Rene P.; Lorenz, Kristina; Renné, Thomas; Heemskerk, Johan W.M.; Sickmann, Albert
    Multi-omics approaches to study platelet mechanisms
    In: Current Opinion in Chemical Biology Vol. 73 (2023) 102253
    Online Full Text: dx.doi.org/ (Open Access)
  • Placke, Jan-Malte; Mertens, Delphine; Tasdogan, Alpaslan; Chorti, Eleftheria; Schadendorf, Dirk; Ugurel, Selma; Rösch, Alexander; Stoffels, Ingo; Klode, Joachim
    Multispectral optoacoustic tomography to differentiate between lymph node metastases and coronavirus-19 vaccine-associated lymphadenopathy
    In: Journal of the European Academy of Dermatology and Venereology Vol. 37 (2023) Nr. 5: Special issue on melanoma: Immune check point and BRAF‐MEK inhibitors in melanoma, pp. 907 - 913
    Online Full Text: dx.doi.org/ (Open Access)
  • Placke, Jan-Malte; Zahn, Maximilian; Zillikens, Hannah; Krefting, Frederik; Lodde, Georg; Zimmer, Lisa; Livingstone, Elisabeth; Hadaschik, Eva; Sucker, Antje; Roesch, Alexander; Tasdogan, Alpaslan; Srinivas, Nalini K.; Schadendorf, Dirk; Becker, Jürgen C.; Ugurel, Selma
    Prognostic factors in the primary care of patients with Merkel cell carcinoma : A monocentric cohort study of 108 patients from a tertiary referral centre
    In: JEADV Clinical Practice Vol. 2 (2023) Nr. 4, pp. 810 - 818
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Solmonson, Ashley; Faubert, Brandon; Gu, Wen; Rao, Aparna; Cowdin, Mitzy A.; Menendez-Montes, Ivan; Kelekar, Sherwin; Rogers, Thomas J.; Pan, Chunxiao; Guevara, Gerardo; Tarangelo, Amy; Zacharias, Lauren G.; Martin-Sandoval, Misty S.; Do, Duyen; Pachnis, Panayotis; Dumesnil, Dennis; Mathews, Thomas P.; Tasdogan, Alpaslan; Pham, An; Cai, Ling; Zhao, Zhiyu; Ni, Min; Cleaver, Ondine; Sadek, Hesham A.; Morrison, Sean J.; DeBerardinis, Ralph J.
    Compartmentalized metabolism supports midgestation mammalian development
    In: Nature Vol. 604 (2022) Nr. 7905, pp. 349 - 353
    Online Full Text: dx.doi.org/ (Open Access)
  • Nascentes Melo, Luiza Martins; Lesner, Nicholas P.; Sabatier, Marie; Ubellacker, Jessalyn M.; Tasdogan, Alpaslan
    Emerging metabolomic tools to study cancer metastasis
    In: Trends in Cancer Vol. 8 (2022) Nr. 12, pp. 988 - 1001
    Online Full Text: dx.doi.org/ (Open Access)
  • Pachnis, Panayotis; Wu, Zheng; Faubert, Brandon; Tasdogan, Alpaslan; Gu, Wen; Shelton, Spencer; Solmonson, Ashley; Rao, Aparna D.; Kaushik, Akash K.; Rogers, Thomas J.; Ubellacker, Jessalyn M.; LaVigne, Collette A.; Yang, Chendong; Ko, Bookyung; Ramesh, Vijayashree; Sudderth, Jessica; Zacharias, Lauren G.; Martin-Sandoval, Misty S.; Do, Duyen; Mathews, Thomas P.; Zhao, Zhiyu; Mishra, Prashant; Morrison, Sean J.; DeBerardinis, Ralph J.
    In vivo isotope tracing reveals a requirement for the electron transport chain in glucose and glutamine metabolism by tumors
    In: Science Advances Vol. 8 (2022) Nr. 35, eabn9550
    Online Full Text: dx.doi.org/ (Open Access)
  • Shen, Bo; Vardy, Kristy; Hughes, Payton; Tasdogan, Alpaslan; Zhao, Zhiyu; Yue, Rui; Crane, Genevieve M.; Morrison, Sean J.
    Integrin alpha11 is an Osteolectin receptor and is required for the maintenance of adult skeletal bone mass
    In: eLife Vol. 8 (2022) pp. e42274
    Online Full Text: dx.doi.org/ (Open Access)
  • Aurora, Arin B.; Khivansara, Vishal; Leach, Ashley; Gill, Jennifer G.; Martin-Sandoval, Misty; Yang, Chendong; Kasitinon, Stacy Y.; Bezwada, Divya; Tasdogan, Alpaslan; Gu, Wen; Mathews, Thomas P.; Zhao, Zhiyu; DeBerardinis, Ralph J.; Morrison, Sean J.
    Loss of glucose 6-phosphate dehydrogenase function increases oxidative stress and glutaminolysis in metastasizing melanoma cells
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 119 (2022) Nr. 6, e2120617119
    Online Full Text: dx.doi.org/ (Open Access)
  • Soflaee, Mona Hoseini; Kesavan, Rushendhiran; Sahu, Umakant; Tasdogan, Alpaslan; Villa, Elodie; Djabari, Zied; Cai, Feng; Tran, Diem H.; Vu, Hieu S.; Ali, Eunus S.; Rion, Halie; O’Hara, Brendan P.; Kelekar, Sherwin; Hallett, James Hughes; Martin, Misty; Mathews, Thomas P.; Gao, Peng; Asara, John M.; Manning, Brendan D.; Ben-Sahra, Issam; Hoxhaj, Gerta
    Purine nucleotide depletion prompts cell migration by stimulating the serine synthesis pathway
    In: Nature Communications Vol. 13 (2022) Nr. 1, 2698
    Online Full Text: dx.doi.org/ (Open Access)
  • Shen, Bo; Tasdogan, Alpaslan; Ubellacker, Jessalyn M.; Zhang, Jingzhu; Nosyreva, Elena D.; Du, Liming; Murphy, Malea M.; Hu, Shuiqing; Yi, Yating; Kara, Nergis; Liu, Xin; Guela, Shay; Jia, Yuemeng; Ramesh, Vijayashree; Embree, Claire; Mitchell, Evann C.; Zhao, Yunduo C.; Ju, Lining A.; Hu, Zhao; Crane, Genevieve M.; Zhao, Zhiyu; Syeda, Ruhma; Morrison, Sean J.
    A mechanosensitive peri-arteriolar niche for osteogenesis and lymphopoiesis
    In: Nature Vol. 591 (2021) Nr. 7850, pp. 438 - 444
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Johnston, Kendra; Pachnis, Panayotis; Tasdogan, Alpaslan; Faubert, Brandon; Zacharias, Lauren G.; Vu, Hieu Sy; Rodgers-Augustyniak, Laurie; Johnson, Allison; Huang, Fang; Ricciardo, Sean; Zhao, Zhiyu; Mathews, Thomas P.; Watt, Tanya; Leavey, Patrick; DeBerardinis, Ralph J.
    Isotope tracing reveals glycolysis and oxidative metabolism in childhood tumors of multiple histologies
    In: Med Vol. 2 (2021) Nr. 4, pp. 395 - 410.e4
    Online Full Text: dx.doi.org/ (Open Access)
  • Devilbiss, Andrew W.; Zhao, Zhiyu; Martin-Sandoval, Misty S.; Ubellacker, Jessalyn M.; Tasdogan, Alpaslan; Agathocleous, Michalis; Mathews, Thomas P.; Morrison, Sean J.
    Metabolomic profiling of rare cell populations isolated by flow cytometry from tissues
    In: eLife Vol. 10 (2021) e61980
    Online Full Text: dx.doi.org/ (Open Access)
  • Tasdogan, Alpaslan; Ubellacker, Jessalyn M.; Morrison, Sean J.
    Redox regulation in cancer cells during metastasis
    In: Cancer Discovery Vol. 11 (2021) Nr. 11, pp. 2682 - 2692
    Online Full Text: dx.doi.org/ (Open Access)
  • Faubert, Brandon; Tasdogan, Alpaslan; Morrison, Sean J.; Mathews, Thomas P.; DeBerardinis, Ralph J.
    Stable isotope tracing to assess tumor metabolism in vivo
    In: Nature Protocols Vol. 16 (2021) Nr. 11, pp. 5123 - 5145
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Zhang, Jingzhu; Cohen, Adi; Shen, Bo; Du, Liming; Tasdogan, Alpaslan; Zhao, Zhiyu; Shane, Elizabeth J.; Morrison, Sean J.
    The effect of parathyroid hormone on osteogenesis is mediated partly by osteolectin
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 118 (2021) Nr. 25, e2026176118
    Online Full Text: dx.doi.org/ (Open Access)
  • Schmid, Teresa; Maier, Julia; Martin, Melanie; Tasdogan, Alpaslan; Tausch, Eugen; Barth, Thomas F.E.; Stilgenbauer, Stephan; Bloehdorn, Johannes; Möller, Peter; Mellert, Kevin
    U-RT1 : A new model for Richter transformation
    In: Neoplasia: An International Journal for Oncology Research Vol. 23 (2021) Nr. 1, pp. 140 - 148
    Online Full Text: dx.doi.org/ (Open Access)
  • Ubellacker, Jessalyn M.; Tasdogan, Alpaslan; Ramesh, Vijayashree; Shen, Bo; Mitchell, Evann C.; Martin-Sandoval, Misty S.; Gu, Zhimin; McCormick, Michael L.; Durham, Alison B.; Spitz, Douglas R.; Zhao, Zhiyu; Mathews, Thomas P.; Morrison, Sean J.
    Lymph protects metastasizing melanoma cells from ferroptosis
    In: Nature Vol. 585 (2020) Nr. 7823, pp. 113 - 118
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Tasdogan, Alpaslan; Faubert, Brandon; Ramesh, Vijayashree; Ubellacker, Jessalyn M.; Shen, Bo; Solmonson, Ashley; Murphy, Malea M.; Gu, Zhimin; Gu, Wen; Martin, Misty; Kasitinon, Stacy Y.; Vandergriff, Travis; Mathews, Thomas P.; Zhao, Zhiyu; Schadendorf, Dirk; DeBerardinis, Ralph J.; Morrison, Sean J.
    Metabolic heterogeneity confers differences in melanoma metastatic potential
    In: Nature Vol. 577 (2020) Nr. 7788, pp. 115 - 120
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Tasdogan, Alpaslan; McFadden, David G.; Mishra, Prashant
    Mitochondrial DNA Haplotypes as Genetic Modifiers of Cancer
    In: Trends in Cancer Vol. 6 (2020) Nr. 12, pp. 1044 - 1058
    Online Full Text: dx.doi.org/
  • Gu, Zhimin; Liu, Yuxuan; Cai, Feng; Patrick, McKenzie; Zmajkovic, Jakub; Cao, Hui; Zhang, Yuannyu; Tasdogan, Alpaslan; Chen, Mingyi; Qi, Le; Liu, Xin; Li, Kailong; Lyu, Junhua; Dickerson, Kathryn E.; Chen, Weina; Ni, Min; Merritt, Matthew E.; Morrison, Sean J.; Skoda, Radek C.; Deberardinis, Ralph J.; Xu, Jian
    Loss of EZH2 reprograms BCAA metabolism to drive leukemic transformation
    In: Cancer Discovery Vol. 9 (2019) Nr. 9, pp. 1228 - 1247
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Kasitinon, Stacy Y.; Eskiocak, Ugur; Martin, M.; Bezwada, D.; Khivansara, Vishal; Tasdogan, Alpaslan; Zhao, Z.; Mathews, Thomas; Aurora, Arin B.; Morrison, Sean J.
    TRPML1 Promotes Protein Homeostasis in Melanoma Cells by Negatively Regulating MAPK and mTORC1 Signaling
    In: Cell Reports Vol. 28 (2019) Nr. 9, pp. 2293 - 2305.e9
    Online Full Text: dx.doi.org/ (Open Access)
  • Kraus, Lea-Franziska; Scheurmann, Natalie; Frenzel, Denis F.; Tasdogan, Alpaslan; Weiss, Johannes M.
    9-cis-Retinoic acid induces a distinct regulatory dendritic cell phenotype that modulates murine delayed-type allergy
    In: Contact Dermatitis Vol. 78 (2018) Nr. 1, pp. 41 - 54
    Online Full Text: dx.doi.org/
  • Ouali Alami, Najwa; Schurr, Christine; Olde Heuvel, Florian; Tang, Linyun; Li, Qian; Tasdogan, Alpaslan; Kimbara, Atsushi; Nettekoven, Matthias; Ottaviani, Giorgio; Raposo, Catarina; Röver, Stephan; Rogers-Evans, Mark; Rothenhäusler, Benno; Ullmer, Christoph; Fingerle, Jürgen; Grether, Uwe; Knuesel, Irene; Boeckers, Tobias M.; Ludolph, Albert; Wirth, Thomas; Roselli, Francesco; Baumann, Bernd
    NF-κB activation in astrocytes drives a stage-specific beneficial neuroimmunological response in ALS
    In: The EMBO Journal Vol. 37 (2018) Nr. 16, e98697
    Online Full Text: dx.doi.org/ (Open Access)
  • Schmidt, Kerstin; Zhang, Qinyu; Tasdogan, Alpaslan; Petzold, Andreas; Dahl, Andreas; Arneth, Borros M.; Slany, Robert; Fehling, Hans Jörg; Kranz, Andrea; Stewart, Adrian Francis; Anastassiadis, Konstantinos
    The H3K4 methyltransferase setd1b is essential for hematopoietic stem and progenitor cell homeostasis in mice
    In: eLife Vol. 7 (2018) e27157
    Online Full Text: dx.doi.org/ (Open Access)

    • Abstracts

  • Placke, Jan-Malte; Kimmig, M.; Griewank, Klaus; Herbst, R.; Terheyden, P.; Utikal, J. S.; Pföhler, C.; Ulrich, J.; Kreuter, A.; Mohr, P.; Gutzmer, R.; Meier, F.; Dippel, E.; Welzel, J.; Engel, Daniel Robert; Kreft, S.; Sucker, A.; Krefting, F.; Lodde, Georg C.; Stoffels, Ingo; Klode, Joachim; Rösch, Alexander; Zimmer, Lisa; Livingstone, Elisabeth; Hadaschik, Eva; Becker, Jürgen C.; Weichenthal, M.; Tasdogan, Alpaslan; Schadendorf, Dirk; Ugurel, Selma;
    Die PD-L1-Expression im Tumor prognostiziert je nach Art des untersuchten Gewebes das Outcome einer Anti-PD-1-basierten Immuntherapie bei metastasiertem Melanom
    33. Deutscher Hautkrebskongress (ADO-Jahrestagung) ; 06.–09. September 2023, Hamburg, Germany,
    In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Vol. 21 (2023) Nr. S4, Special Issue: Abstractband anlässlich des 33. Deutschen Hautkrebskongresses (ADO‐Jahrestagung) 06.–09. September 2023 Hamburg, pp. 27 - 28
    Online Full Text: dx.doi.org/ (Open Access)
  • Placke, Jan-Malte; Mohr, Peter; Bluhm, Leonie; Tasdogan, Alpaslan; Schadendorf, Dirk; Ugurel, Selma;
    Predictors of long-term survival of Stage IV melanoma patients: a multicenter DeCOG study on 395 patients from the prospective skin cancer registry ADOREG
    52. Tagung der Deutschen Dermatologischen Gesellschaft, Vereinigung Deutschsprachiger Dermatologen e. V., 26.-29.04.2023, Berlin,
    In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Vol. 21 (2023) Nr. S1, Special Issue: Abstractband anlässlich der 52. Tagung der Deutschen Dermatologischen Gesellschaft, Vereinigung Deutschsprachiger Dermatologen e. V. 26. bis 29. April 2023, Berlin, pp. 9 - 27
    Online Full Text: dx.doi.org/ (Open Access)
  • Placke, Jan-Malte; Mohr, P.; Bluhm, L.; Engel, Daniel Robert; Franklin, Cindy; Zaremba, Anne; Krefting, F.; Lodde, Georg; Zimmer, Lisa; Livingstone, Elisabeth; Becker, Jürgen C.; Tasdogan, Alpaslan; Rösch, Alexander; Schadendorf, Dirk; Ugurel, Selma; et al.;
    Predictors of long-term survival of stage IV melanoma patients : a multicenter DeCOG study on 539 patients from the prospective skin cancer registry ADOREG
    32. Deutscher Hautkrebskongress (ADO-Jahrestagung), 14.–17. September 2022, Hannover, Germany,
    In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Vol. 20 (2022) Nr. S3, pp. 16 - 17
    Online Full Text: dx.doi.org/

    • Posters / Proceedings posters

  • Placke, Jan-Malte; Kimmig, M.; Griewank, Klaus; Hadaschik, Eva; Herbst, R.; Terheyden, P.; Utikal, J.; Pfoehler, C.; Ulrich, J.; Kreuter, A.; Mohr, P.; Gutzmer, R.; Meier, F.; Dippel, E.; Welzel, J.; Becker, Jürgen C.; Weichenthal, M.; Tasdogan, Alpaslan; Schadendorf, Dirk; Ugurel-Becker, Selma;
    Tumor PD-L1 predicts the outcome of PD-1-based immunotherapy in metastatic melanoma depending on the type of tissue examined
    ESMO Congress 2023 ; 20 - 24 October 2023, Madrid, Spain,
    In: Annals of Oncology Vol. 34 (2023) Nr. Supplement 2: Abstract Book of the ESMO Congress 2023, 20 - 24 October 2023, pp. S695
    Online Full Text: dx.doi.org/