ZMB Member Dietmar Lohmann
ZMB Member
Dietmar Lohmann
Next Member
Prof. Dr. Dietmar Lohmann
Institute of Human Genetics
University Hospital Essen
Hufelandstr. 55
45122 Essen
- +49 201 723 4562
- Website
- Selected Publications
- Publication Metrics
- ZMB Research Program
Molecular and Chemical Cell Biology
Research Overview
Retinoblastoma
- Determining the genetic architecture underlying predisposition to retinoblastoma
- Identification of risk factors for development of extraocular neoplasms in patients with retinoblastoma
- Analysis of changes of the genetic landscape during retinoblastoma progression
Uveal Melanoma
- Identification of heritable genetic alterations that alter the risk for uveal melanoma
- Development of prognostic and predictive biomarkers
- Determining somatic genetic alterations linked to metastasizing uveal melanoma
Selected Publications
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Comparing efficacy and side effects of two systemic chemotherapy regimens for eye-preserving therapy in children with retinoblastomaIn: Pediatric Blood and Cancer Vol. 69 (2022) Nr. 2, e29362Online Full Text: dx.doi.org/ (Open Access)
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RB1-Negative Retinal Organoids Display Proliferation of Cone Photoreceptors and Loss of Retinal DifferentiationIn: Cancers Vol. 14 (2022) Nr. 9, 2166Online Full Text: dx.doi.org/ (Open Access)
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TFF1 in Aqueous Humor : A Potential New Biomarker for RetinoblastomaIn: Cancers Vol. 14 (2022) Nr. 3, 677Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Eye tumors in childhood as first sign of tumor predisposition syndromes : Insights from an observational study conducted in Germany and AustriaIn: Cancers Vol. 13 (2021) Nr. 8, pp. 1876Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Introduction of a variant classification system for analysis of genotype-phenotype relationships in heritable retinoblastomaIn: Cancers Vol. 13 (2021) Nr. 7, pp. 1605Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterationsIn: Acta Neuropathologica Vol. 139 (2020) Nr. 2, pp. 243 - 257Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Ectopic intracranial retinoblastoma in a 3.5-month-old infant without eye involvement and without evidence of heritabilityIn: Pediatric Blood and Cancer Vol. 66 (2019) Nr. 5, e27599Online Full Text: dx.doi.org/
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GNAQ Q209R Mutations Are Highly Specific for Circumscribed Choroidal HemangiomaIn: Cancers Vol. 11 (2019) Nr. 7, pp. 1031Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Retinoblastoma with late metastatic spread : a case reportIn: Pediatric Blood and Cancer Vol. 66 (2019) Nr. 6, e27656Online Full Text: dx.doi.org/
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Author Correction : The landscape of genomic alterations across childhood cancersIn: Nature Vol. 559 (2018) Nr. 7714, pp. E10Online Full Text: dx.doi.org/ (Open Access)
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DNA methylation-based classification of central nervous system tumoursIn: Nature Vol. 555 (2018) Nr. 7697, pp. 469 - 474Online Full Text: dx.doi.org/ (Open Access)
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The landscape of genomic alterations across childhood cancersIn: Nature Vol. 555 (2018) Nr. 7696, pp. 321 - 327Online Full Text: dx.doi.org/ (Open Access)
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Incidence of second cancers after radiotherapy and systemic chemotherapy in heritable retinoblastoma survivors : a report from the German reference centerIn: Pediatric Blood and Cancer Vol. 64 (2017) Nr. 1, pp. 71 - 80Online Full Text: dx.doi.org/
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Pediatric second primary malignancies after retinoblastoma treatmentIn: Pediatric Blood and Cancer Vol. 62 (2015) Nr. 10, pp. 1799 - 1804Online Full Text: dx.doi.org/ (Open Access)
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Characterisation of retinoblastomas without RB1 mutations: Genomic, gene expression, and clinical studiesIn: The Lancet Oncology Vol. 14 (2013) Nr. 4, pp. 327 - 334Online Full Text: dx.doi.org/
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Exome sequencing identifies recurrent somatic mutations in EIF1AX and SF3B1 in uveal melanoma with disomy 3In: Nature Genetics Vol. 45 (2013) Nr. 8, pp. 933 - 936Online Full Text: dx.doi.org/
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Sporadic unilateral retinoblastoma or first sign of bilateral disease?
44th Congress of the International Society of Paediatric Oncology (SIOP) 2012, 5th–8th October, 2012, London, UK,In: Pediatric Blood and Cancer Vol. 59 (2012) Nr. 6, pp. 1064 - 1064Online Full Text: dx.doi.org/ -
Anthropogenic greenhouse gas contribution to flood risk in England and Wales in autumn 2000In: Nature Vol. 470 (2011) Nr. 7334, pp. 382 - 385Online Full Text: dx.doi.org/
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Mutations in genes encoding subunits of RNA polymerases I and III cause Treacher Collins syndromeIn: Nature Genetics Vol. 43 (2011) Nr. 1, pp. 20 - 22Online Full Text: dx.doi.org/
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A variant allele of Growth Factor Independence 1 (GFI1) is associated with acute myeloid leukemiaIn: Blood Vol. 115 (2010) Nr. 12, pp. 2462 - 2472Online Full Text: dx.doi.org/
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Neurotrophin receptor expression in human primary retinoblastomas and retinoblastoma cell linesIn: Pediatric Blood and Cancer Vol. 50 (2008) Nr. 2, pp. 218 - 222Online Full Text: dx.doi.org/