As part of our CRC 1430 seminar series, we are delighted to present our next guest speaker Dr. Florian Rambow from the UK Essen, Germany. His talk is entitled "Lessons from the melanoma ecosystem".

Over the last years, cancer research has shifted gears with the advent of single-cell technologies. Recent advances in molecular biology, microfluidics, and nanotechnology make it now possible to measure genomic, epigenomic, and proteomic changes in single (cancer) cells even in a spatially resolved fashion. These techniques have already granted groundbreaking insights into cancer biology by revealing the complex and so far underestimated heterogeneity of a single tumor (millions of cells), which is a major obstacle to successful anti-cancer therapy. My research makes use of these cutting-edge single-cell approaches to create high-resolution tumor maps for melanoma, the most lethal form of skin cancer.