Publications 2022
https://pubmed.ncbi.nlm.nih.gov/36038749/
Acid sphingomyelinase deactivation post-ischemia promotes brain angiogenesis and remodeling by small extracellular vesicles
Basic Res Cardiol; 2022-12-15; 117(1): ; doi:10.1007/s00395-022-00950-7
https://link.springer.com/article/10.1007/s00395-022-00950-7
Mohamud Yusuf A, Hagemann N, Zhang X, Zafar M, Hussner T, Bromkamp C, Martiny C, Tertel T, Börger V, Schumacher F, Solari FA, Hasenberg M, Kleinschnitz C, Doeppner TR, Kleuser B, Sickmann A, Gunzer M, Giebel B, Kolesnick R, Gulbins E, Hermann DM
https://pubmed.ncbi.nlm.nih.gov/36494632/
Biofilm infection of a central venous port-catheter caused by Mycobacterium avium complex in an immunocompetent child with cystic fibrosis.
BMC Infectious Diseases; 2022-12-09; 22(1): ; doi:10.1186/s12879-022-07899-x
https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-022-07899-x
Kavvalou A, Stehling F, Tschiedel E, Kehrmann J, Walkenfort B, Hasenberg M, Olivier M, Steindor M
https://pubmed.ncbi.nlm.nih.gov/36477465/
Macrophage-Orbital Fibroblast Interaction and Hypoxia Promote Inflammation and Adipogenesis in Graves’ Orbitopathy.
Endocrinology; 2022-12-07; 164(2): ; doi:10.1210/endocr/bqac203
https://academic.oup.com/endo/article-abstract/164/2/bqac203/6881427?redirectedFrom=fulltext&login=false
Görtz GE, Philipp S, Bruderek K, Jesenek C, Horstmann M, Henning Y, Oeverhaus M, Daser A, Bechrakis NE, Eckstein A, Brandau S, Berchner-Pfannschmidt U
https://pubmed.ncbi.nlm.nih.gov/36383102/
A switchable DNA origami/plasmonic hybrid device with a precisely tuneable DNA-free interparticle gap
Chemical Communications; 2022-12-06; 58(97): 13479-13482; doi:10.1039/d2cc05324a
https://pubs.rsc.org/en/content/articlelanding/2022/CC/D2CC05324A
Erkelenz M, Kosinski R, Giesler H, Sritharan O, Jose J, Saccà B, Schlücker S
https://pubmed.ncbi.nlm.nih.gov/36524111/
Three-dimensional analyses of vascular network morphology in a murine lymph node by X-ray phase-contrast tomography with a 2D Talbot array
Frontiers in Immunology; 2022-11-29; 13(): ; doi:10.3389/fimmu.2022.947961
https://www.frontiersin.org/articles/10.3389/fimmu.2022.947961/full
Schwarzenberg FL, Schütz P, Hammel JU, Riedel M, Bartl J, Bordbari S, Frank SC, Walkenfort B, Busse M, Herzen J, Lohr C, Wülfing C, Henne S
https://pubmed.ncbi.nlm.nih.gov/36327970/
Growth Rate and Thermal Properties of DNA Origami Filaments.
Nano Letters; 2022-11-23; 22(22): 8818-8826; doi:10.1021/acs.nanolett.2c02255
https://pubs.acs.org/doi/10.1021/acs.nanolett.2c02255
Stenke LJ, Saccà B
https://pubmed.ncbi.nlm.nih.gov/36376973/
Epigenome-wide analysis of T-cell large granular lymphocytic leukemia identifies BCL11B as a potential biomarker.
Clinical Epigenetics; 2022-11-14; 14(148): ; doi:10.1186/s13148-022-01362-z
https://clinicalepigeneticsjournal.biomedcentral.com/articles/10.1186/s13148-022-01362-z
Johansson P, Laguna T, Ossowski J, Pancaldi V, Brauser M, Dührsen U, Keuneke L, Queiros A, Richter J, Martín-Subero JI, Siebert R, Schlegelberger B, Küppers R, Dürig J, Murga Penas EM, Carillo-de Santa Pau E, Bergmann AK
https://pubmed.ncbi.nlm.nih.gov/35977505/
During early stages of cancer, neutrophils initiate anti-tumor immune responses in tumor-draining lymph nodes.
Cell Reports; 2022-08-16; 40(7): ; doi:10.1016/j.celrep.2022.111171
https://www.sciencedirect.com/science/article/pii/S2211124722009846?via%3Dihub
Pylaeva E, Korschunow G, Spyra I, Bordbari S, Siakaeva E, Ozel I, Domnich M, Squire A, Hasenberg A, Thangavelu K, Hussain T, Goetz M, Lang KS, Gunzer M, Hansen W, Buer J, Bankfalvi A, Lang S, Jablonska J
https://pubmed.ncbi.nlm.nih.gov/35928516/
Platelet depletion does not alter long-term functional outcome after cerebral ischaemia in mice
Brain Behav Immun Health; 2022-07-21; 24(): ; doi:10.1016/j.bbih.2022.100493
https://www.sciencedirect.com/science/article/pii/S2666354622000837?via%3Dihub
Steubing RD, Szepanowski F, David C, Mohamud Yusuf A, Mencl S, Mausberg AK, Langer HF, Sauter M, Deuschl C, Forsting M, Fender AC, Hermann DM, Casas AI, Langhauser F, Kleinschnitz C
https://pubmed.ncbi.nlm.nih.gov/35723257/
ERG activity is regulated by endothelial FAK coupling with TRIM25/USP9x in vascular patterning..
Development; 2022-07-01; 149(13): ; doi:https://doi.org/10.1242/dev.200528
https://journals.biologists.com/dev/article/149/13/dev200528/275974/ERG-activity-is-regulated-by-endothelial-FAK
D'Amico G, Fernandez I, Gómez-Escudero J, Kim H, Maniati E, Azman MS, Mardakheh FK, Serrels B, Serrels A, Parsons M, Squire A, Birdsey GM, Randi AM, Bolado-Carrancio A, Gangeswaran R, Reynolds LE, Bodrug N, Wang Y, Wang J, Meier P, Hodivala-Dilke KM
https://pubmed.ncbi.nlm.nih.gov/35890282/
Design and Functional Characterization of HIV-1 Envelope Protein-Coupled T Helper Liposomes.
Pharmaceutics; 2022-06-30; 14(7): 1385; doi:10.3390/pharmaceutics14071385
https://www.mdpi.com/1999-4923/14/7/1385
Damm D, Suleiman E, Theobald H, Wagner JT, Batzoni M, Ahlfeld Née Kohlhauser B, Walkenfort B, Albrecht JC, Ingale J, Yang L, Hasenberg M, Wyatt RT, Vorauer-Uhl K, Überla K, Temchura V
IFNAR1 Deficiency Impairs Immunostimulatory Properties of Neutrophils in Tumor-Draining Lymph Nodes.
Frontiers in Immunology; 2022-06-27; 13(): ; doi:10.3389/fimmu.2022.878959
https://www.frontiersin.org/articles/10.3389/fimmu.2022.878959/full
Hussain T, Domnich M, Bordbari S, Pylaeva E, Siakaeva E, Spyra I, Ozel I, Droege F, Squire A, Lienenklaus S, Sutter K, Hasenberg A, Gunzer M, Lang S, Jablonska J
https://pubmed.ncbi.nlm.nih.gov/35737452/
Gold Nanorods Induce Endoplasmic Reticulum Stress and Autocrine Inflammatory Activation in Human Neutrophils.
ACS Nano; 2022-06-23; 16(4): ; doi:10.1021/acschembio.0c00757
https://pubs.acs.org/doi/10.1021/acsnano.2c03586
Schirrmann R, Erkelenz M, Lamers K, Sritharan O, Nachev M, Sures B, Schlücker S, Brandau S
Bacteria (E. coli ) take up ultrasmall gold nanoparticles (2 nm) as shown by different optical microscopic techniques (CLSM, SIM, STORM).
Nano Select; 2022-06-14; (): ; doi:10.1002/nano.202200049
https://onlinelibrary.wiley.com/doi/full/10.1002/nano.202200049
Bia?as N, Sokolova V, van der Meer SB, Knuschke T, Ruks T, Klein K, Westendorf AM, Epple M
https://pubmed.ncbi.nlm.nih.gov/35697379/
Innate immune receptor signaling induces transient melanoma dedifferentiation while preserving immunogenicity.
Journal for ImmunoTherapy of Cancer; 2022-06-10; 6(): ; doi:10.1136/jitc-2021-003863
https://jitc.bmj.com/content/10/6/e003863.long
Thier B, Zhao F, Stupia S, Brüggemann A, Koch J, Schulze N, Horn S, Coch C, Hartmann G, Sucker A, Schadendorf D, Paschen A
https://pubmed.ncbi.nlm.nih.gov/35650266/
Persister state-directed transitioning and vulnerability in melanoma.
Nature Communications; 2022-06-01; 13(1): 3055; doi:https://doi.org/10.1038/s41467-022-30641-9
https://doi.org/10.1038/s41467-022-30641-9
Chauvistré H, Shannan B, Daignault-Mill SM, Ju RJ, Picard D, Egetemaier S, Váraljai R, Gibhardt CS, Sechi A, Kaschani F, Keminer O, Stehbens SJ, Liu Q, Yin X, Jeyakumar K, Vogel FCE, Krepler C, Rebecca VW, Kubat L, Lueong SS, Forster J, Horn S, Remke M, Ehrmann M, Paschen A, Becker JC, Helfrich I, Rauh D, Kaiser M, Gul S, Herlyn M, Bogeski I, Rodríguez-López JN, Haass NK, Schadendorf D, Roesch A.
https://pubmed.ncbi.nlm.nih.gov/35609021/
Long-term treatment with chloroquine increases lifespan in middle-aged male mice possibly via autophagy modulation, proteasome inhibition and glycogen metabolism.
Aging; 2022-05-23; 14(): ; doi:10.18632/aging.204069
https://www.aging-us.com/article/204069/text
Doeppner TR, Coman C, Burdusel D, Ancuta DL, Brockmeier U, Pirici DN, Yaoyun K, Hermann DM, Popa-Wagner A
https://pubmed.ncbi.nlm.nih.gov/35565295/
RB1-Negative Retinal Organoids Display Proliferation of Cone Photoreceptors and Loss of Retinal Differentiation
Cancers; 2022-04-26; 14(9): 2166; doi:10.3390/cancers14092166
Kanber D, Woesfeld J, Döpper H, Bozet M, Brenzel A, Altmüller J, Kilpert D, Pommerenke C, Steenpass L
https://pubmed.ncbi.nlm.nih.gov/34530440/
Sublamina-Specific Dynamics and Ultrastructural Heterogeneity of Layer 6 Excitatory Synaptic Boutons in the Adult Human Temporal Lobe Neocortex.
Cerebral Cortex; 2022-04-20; 32(9): 1840-1865; doi: https://doi.org/10.1093/cercor/bhab315
https://academic.oup.com/cercor/advance-article/doi/10.1093/cercor/bhab315/6371350
Schmuhl-Giesen S, Rollenhagen A, Walkenfort B, Yakoubi R, Sätzler K, Miller D, von Lehe M, Hasenberg M, Lübke JHR
Efficient Small Extracellular Vesicles (EV) Isolation Method and Evaluation of EV-Associated DNA Role in Cell–Cell Communication in Cancer
Cancers; 2022-04-20; 14(9): 2068; doi:https://doi.org/10.3390/cancers14092068
https://doi.org/10.3390/cancers14092068
Chetty VK, Ghanam J, Anchan S, Reinhardt K, Brenzel A, Gelléri M, Cremer C, Grueso-Navarro E, Schneider M, von Neuhoff N, Reinhardt D, Jablonska J, Nazarenko I, Thakur BK
https://pubmed.ncbi.nlm.nih.gov/34751438/
SIRT1-mediated deacetylation of FOXO3a transcription factor supports pro-angiogenic activity of interferon-deficient tumor-associated neutrophils
International Journal of cancer; 2022-04-01; 150(7): 1198-1211; doi:10.1002/ijc.33871
https://onlinelibrary.wiley.com/doi/10.1002/ijc.33871
Bordbari S, Mörchen B, Pylaeva E, Siakaeva E, Spyra I, Domnich M, Droege F, Kanaan O, Lang KS, Schadendorf D, Lang S, Helfrich I, Jablonska J
Free flow electrophoresis allows quick and reproducible preparation of extracellular vesicles from conditioned cell culture media
Extracellular Vesicles and Circulating Nucleic Acids; 2022-03-22; 3(): 31-48; doi:
https://evcna.com/article/view/4702
Staubach S, Tertel T, Walkenfort B, Buschmann D, Pfaffl MW, Weber G, Giebel B
https://pubmed.ncbi.nlm.nih.gov/35289361/
Inhibition of azole-resistant Aspergillus fumigatus biofilm at various formation stages by antifungal drugs, including olorofim
Journal of Antimicrobial Chemotherapy; 2022-03-15; (): ; doi:10.1093/jac/dkac062
https://academic.oup.com/jac/advance-article/doi/10.1093/jac/dkac062/6548677
Kirchhoff L, Dittmer S, Furnica DT, Buer J, Steinmann E, Rath PM, Steinmann J
https://pubmed.ncbi.nlm.nih.gov/34779257/
An Early Wave of Macrophage Infiltration Intertwined with Antigen-Specific Proinflammatory T Cells and Browning of Adipose Tissue Characterizes the Onset of Orbital Inflammation in a Mouse Model of Graves' Orbitopathy.
Thyroid; 2022-03-01; 32(3): 283-293; doi:10.1089/thy.2021.0464
https://www.liebertpub.com/doi/10.1089/thy.2021.0464?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed
Philipp S, Horstmann M, Hose M, Daser A, Görtz GA, Jesenek C, Flögel U, Hansen W, Bechrakis N, Banga JPS, Eckstein A, Berchner-Pfannschmidt U
https://pubmed.ncbi.nlm.nih.gov/35251021/
Reactivity of NK Cells Against Ovarian Cancer Cells Is Maintained in the Presence of Calcium Phosphate Nanoparticles
Frontiers in Immunology; 2022-02-18; 13(830938): ; doi:https://doi.org/10.3389/fimmu.2022.830938
https://www.frontiersin.org/articles/10.3389/fimmu.2022.830938/full
Hrvat A, Schmidt M, Obholzer M, Benders S, Kollenda S, Horn PA, Epple M, Brandau S, Mallmann-Gottschalk N
https://pubmed.ncbi.nlm.nih.gov/35159369/
Induction of Survival of Motor Neuron (SMN) Protein Deficiency in Spinal Astrocytes by Small Interfering RNA as an In Vitro Model of Spinal Muscular Atrophy
Cells; 2022-02-05; 11(3): 558; doi:10.3390/cells11030558
https://www.mdpi.com/2073-4409/11/3/558/htm
Leo M, Schmitt LI, Fleischer M, Steffen R, Osswald C, Kleinschnitz C, Hagenacker T
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834272/
Distinct Actions of the Thyroid Hormone Transporters Mct8 and Oatp1c1 in Murine Adult Hippocampal Neurogenesis
Cells; 2022-02-02; 11(3): 524; doi:https://doi.org/10.3390/cells11030524
https://www.mdpi.com/2073-4409/11/3/524/htm
Mayerl S, Alcaide Martin A, Bauer R, Schwaninger M, Heuer H, Ffrench-Constant C
https://pubmed.ncbi.nlm.nih.gov/34848338/
Post-ischemic protein restriction induces sustained neuroprotection, neurological recovery, brain remodeling, and gut microbiota rebalancing.
Brain, Behavior, and Immunity; 2022-02-01; 100(): 134-144; doi: 10.1016/j.bbi.2021.11.016
https://www.sciencedirect.com/science/article/pii/S0889159121006127
de Carvalho TS, Singh V, Yusuf AM, Wang J, Schultz Moreira AR, Sanchez-Mendoza EH, Sardardi M, Nascentes Melo LM, Doeppner TR, Kehrmann J, Scholtysik R, Hitpass L, Gunzer M, Hermann DM
https://pubmed.ncbi.nlm.nih.gov/34389849/
Targeting early stages of cardiotoxicity from anti-PD1 immune checkpoint inhibitor therapy.
European Heart Journal; 2022-01-31; (): ; doi: 10.1093/eurheartj/ehab430
https://academic.oup.com/eurheartj/advance-article-abstract/doi/10.1093/eurheartj/ehab430/6352226?redirectedFrom=fulltext
Michel L, Helfrich I, Hendgen-Cotta UB, Mincu RI, Korste S, Mrotzek SM, Spomer A, Odersky A, Rischpler C, Herrmann K, Umutlu L, Coman C, Ahrends R, Sickmann A, Löffek S, Livingstone E, Ugurel S, Zimmer L, Gunzer M, Schadendorf D, Totzeck M, Rassaf T
https://pubmed.ncbi.nlm.nih.gov/35100966/
Characterisation of cold-induced mitochondrial fission in porcine aortic endothelial cells.
Journal of Molecular Medicine; 2022-01-31; 28(1): ; doi:10.1186/s10020-021-00430-z
https://molmed.biomedcentral.com/articles/10.1186/s10020-021-00430-z
Quiring L, Walter B, Lohaus N, Schwan D, Rech A, Dlugos A, Rauen U
https://pubmed.ncbi.nlm.nih.gov/35154145/
The Splenic Marginal Zone in Children Is Characterized by a Subpopulation of CD27-Negative, Lowly IGHV-Mutated B Cells
Frontiers in Immunology; 2022-01-27; 13(): ; doi:10.3389/fimmu.2022.825619
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.825619/full
Kibler A, Budeus B, Küppers R, Seifert M
https://pubmed.ncbi.nlm.nih.gov/35038735/
Canonical Thyroid Hormone Receptor ? Action Stimulates Hepatocyte Proliferation in Male Mice
Endocrinology; 2022-01-17; 163(3): ; doi:10.1210/endocr/bqac003
https://academic.oup.com/endo/article/163/3/bqac003/6509895?login=true#330181598
Hönes GS, Kerp H, Hoppe C, Kowalczyk M, Zwanziger D, Baba HA, Führer D, Moeller LC
https://pubmed.ncbi.nlm.nih.gov/34339499/
Thyroid Hormone Transporter Deficiency in Mice Impacts Multiple Stages of GABAergic Interneuron Development.
Cerebral Cortex; 2022-01-10; 32(2): 329-341; doi:10.1093/cercor/bhab211
https://academic.oup.com/cercor/article/32/2/329/6333075?login=false
Mayerl S, Chen J, Salveridou E, Boelen A, Darras VM, Heuer H
https://pubmed.ncbi.nlm.nih.gov/35013174/
Progranulin mediates immune evasion of pancreatic ductal adenocarcinoma through regulation of MHCI expression.
Nature communications; 2022-01-10; 13(1): 156; doi:https://doi.org/10.1038/s41467-021-27088-9
https://www.nature.com/articles/s41467-021-27088-9
Cheung PF, Yang J, Fang R, Borgers A, Krengel K, Stoffel A, Althoff K, Yip CW, Siu EHL, Ng LWC, Lang KS, Cham LB, Engel DR, Soun C, Cima I, Scheffler B, Striefler JK, Sinn M, Bahra M, Pelzer U, Oettle H, Markus P, Smeets EMM, Aarntzen EHJG, Savvatakis K, Liffers ST, Lueong SS, Neander C, Bazarna A, Zhang X, Paschen A, Crawford HC, Chan AWH, Cheung ST, Siveke JT.
https://pubmed.ncbi.nlm.nih.gov/34985948/
The role of DNA nanostructures in the catalytic properties of an allosterically regulated protease.
Science Advances; 2022-01-07; 8(1): ; doi:10.1126/sciadv.abk0425
https://www.science.org/doi/10.1126/sciadv.abk0425?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
Kosinski R, Perez JM, Schöneweiß EC, Ruiz-Blanco YB, Ponzo I, Bravo-Rodriguez K, Erkelenz M, Schlücker S, Uhlenbrock G, Sanchez-Garcia E, Saccà B
https://pubmed.ncbi.nlm.nih.gov/34847707/
Postischemic Neuroprotection Associated With Anti-Inflammatory Effects by Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles in Aged Mice.
Stroke; 2022-01-01; 53(1): ; doi:10.1161/STROKEAHA.121.035821
https://www.ahajournals.org/doi/full/10.1161/STROKEAHA.121.035821?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org
Wang C, Börger V, Mohamud Yusuf A, Tertel T, Stambouli O, Murke F, Freund N, Kleinschnitz C, Herz J, Gunzer M, Popa-Wagner A, Doeppner TR, Giebel B, Hermann DM
Fine structure of Nucleophaga striatae (Rozellomycota) developing within the nucleus of the free-living amoeba Thecamoeba foliovenanda
Endocytobiosis and Cell Research; 2021-09-09; 31(1): 1-4; doi:
https://zs.thulb.uni-jena.de/receive/jportal_jparticle_01026785
Michel R, Jastrow H , Corsaro D, Walochnik J, Mosel F, Müller, KD
https://pubmed.ncbi.nlm.nih.gov/35969658/
Deciphering the Emulsification Process to Create an Albumin-Perfluorocarbon-(o/w) Nanoemulsion with High Shelf Life and Bioresistivity.
Langmuir; 2021-08-30; 38(34): ; doi:10.1021/acs.langmuir.1c03388
https://pubs.acs.org/doi/10.1021/acs.langmuir.1c03388
Jaegers J, Haferkamp S, Arnolds O, Moog D, Wrobeln A, Nocke F, Cantore M, Pütz S, Hartwig A, Franzkoch R, Psathaki OE, Jastrow H, Schauerte C, Stoll R, Kirsch M, Ferenz KB
Acid sphingomyelinase deactivation post-ischemia promotes brain angiogenesis and remodeling by small extracellular vesicles
Basic Res Cardiol; 2022-12-15; 117(1): ; doi:10.1007/s00395-022-00950-7
https://link.springer.com/article/10.1007/s00395-022-00950-7
Mohamud Yusuf A, Hagemann N, Zhang X, Zafar M, Hussner T, Bromkamp C, Martiny C, Tertel T, Börger V, Schumacher F, Solari FA, Hasenberg M, Kleinschnitz C, Doeppner TR, Kleuser B, Sickmann A, Gunzer M, Giebel B, Kolesnick R, Gulbins E, Hermann DM
https://pubmed.ncbi.nlm.nih.gov/36494632/
Biofilm infection of a central venous port-catheter caused by Mycobacterium avium complex in an immunocompetent child with cystic fibrosis.
BMC Infectious Diseases; 2022-12-09; 22(1): ; doi:10.1186/s12879-022-07899-x
https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-022-07899-x
Kavvalou A, Stehling F, Tschiedel E, Kehrmann J, Walkenfort B, Hasenberg M, Olivier M, Steindor M
https://pubmed.ncbi.nlm.nih.gov/36477465/
Macrophage-Orbital Fibroblast Interaction and Hypoxia Promote Inflammation and Adipogenesis in Graves’ Orbitopathy.
Endocrinology; 2022-12-07; 164(2): ; doi:10.1210/endocr/bqac203
https://academic.oup.com/endo/article-abstract/164/2/bqac203/6881427?redirectedFrom=fulltext&login=false
Görtz GE, Philipp S, Bruderek K, Jesenek C, Horstmann M, Henning Y, Oeverhaus M, Daser A, Bechrakis NE, Eckstein A, Brandau S, Berchner-Pfannschmidt U
https://pubmed.ncbi.nlm.nih.gov/36383102/
A switchable DNA origami/plasmonic hybrid device with a precisely tuneable DNA-free interparticle gap
Chemical Communications; 2022-12-06; 58(97): 13479-13482; doi:10.1039/d2cc05324a
https://pubs.rsc.org/en/content/articlelanding/2022/CC/D2CC05324A
Erkelenz M, Kosinski R, Giesler H, Sritharan O, Jose J, Saccà B, Schlücker S
https://pubmed.ncbi.nlm.nih.gov/36524111/
Three-dimensional analyses of vascular network morphology in a murine lymph node by X-ray phase-contrast tomography with a 2D Talbot array
Frontiers in Immunology; 2022-11-29; 13(): ; doi:10.3389/fimmu.2022.947961
https://www.frontiersin.org/articles/10.3389/fimmu.2022.947961/full
Schwarzenberg FL, Schütz P, Hammel JU, Riedel M, Bartl J, Bordbari S, Frank SC, Walkenfort B, Busse M, Herzen J, Lohr C, Wülfing C, Henne S
https://pubmed.ncbi.nlm.nih.gov/36327970/
Growth Rate and Thermal Properties of DNA Origami Filaments.
Nano Letters; 2022-11-23; 22(22): 8818-8826; doi:10.1021/acs.nanolett.2c02255
https://pubs.acs.org/doi/10.1021/acs.nanolett.2c02255
Stenke LJ, Saccà B
https://pubmed.ncbi.nlm.nih.gov/36376973/
Epigenome-wide analysis of T-cell large granular lymphocytic leukemia identifies BCL11B as a potential biomarker.
Clinical Epigenetics; 2022-11-14; 14(148): ; doi:10.1186/s13148-022-01362-z
https://clinicalepigeneticsjournal.biomedcentral.com/articles/10.1186/s13148-022-01362-z
Johansson P, Laguna T, Ossowski J, Pancaldi V, Brauser M, Dührsen U, Keuneke L, Queiros A, Richter J, Martín-Subero JI, Siebert R, Schlegelberger B, Küppers R, Dürig J, Murga Penas EM, Carillo-de Santa Pau E, Bergmann AK
https://pubmed.ncbi.nlm.nih.gov/35977505/
During early stages of cancer, neutrophils initiate anti-tumor immune responses in tumor-draining lymph nodes.
Cell Reports; 2022-08-16; 40(7): ; doi:10.1016/j.celrep.2022.111171
https://www.sciencedirect.com/science/article/pii/S2211124722009846?via%3Dihub
Pylaeva E, Korschunow G, Spyra I, Bordbari S, Siakaeva E, Ozel I, Domnich M, Squire A, Hasenberg A, Thangavelu K, Hussain T, Goetz M, Lang KS, Gunzer M, Hansen W, Buer J, Bankfalvi A, Lang S, Jablonska J
https://pubmed.ncbi.nlm.nih.gov/35928516/
Platelet depletion does not alter long-term functional outcome after cerebral ischaemia in mice
Brain Behav Immun Health; 2022-07-21; 24(): ; doi:10.1016/j.bbih.2022.100493
https://www.sciencedirect.com/science/article/pii/S2666354622000837?via%3Dihub
Steubing RD, Szepanowski F, David C, Mohamud Yusuf A, Mencl S, Mausberg AK, Langer HF, Sauter M, Deuschl C, Forsting M, Fender AC, Hermann DM, Casas AI, Langhauser F, Kleinschnitz C
https://pubmed.ncbi.nlm.nih.gov/35723257/
ERG activity is regulated by endothelial FAK coupling with TRIM25/USP9x in vascular patterning..
Development; 2022-07-01; 149(13): ; doi:https://doi.org/10.1242/dev.200528
https://journals.biologists.com/dev/article/149/13/dev200528/275974/ERG-activity-is-regulated-by-endothelial-FAK
D'Amico G, Fernandez I, Gómez-Escudero J, Kim H, Maniati E, Azman MS, Mardakheh FK, Serrels B, Serrels A, Parsons M, Squire A, Birdsey GM, Randi AM, Bolado-Carrancio A, Gangeswaran R, Reynolds LE, Bodrug N, Wang Y, Wang J, Meier P, Hodivala-Dilke KM
https://pubmed.ncbi.nlm.nih.gov/35890282/
Design and Functional Characterization of HIV-1 Envelope Protein-Coupled T Helper Liposomes.
Pharmaceutics; 2022-06-30; 14(7): 1385; doi:10.3390/pharmaceutics14071385
https://www.mdpi.com/1999-4923/14/7/1385
Damm D, Suleiman E, Theobald H, Wagner JT, Batzoni M, Ahlfeld Née Kohlhauser B, Walkenfort B, Albrecht JC, Ingale J, Yang L, Hasenberg M, Wyatt RT, Vorauer-Uhl K, Überla K, Temchura V
IFNAR1 Deficiency Impairs Immunostimulatory Properties of Neutrophils in Tumor-Draining Lymph Nodes.
Frontiers in Immunology; 2022-06-27; 13(): ; doi:10.3389/fimmu.2022.878959
https://www.frontiersin.org/articles/10.3389/fimmu.2022.878959/full
Hussain T, Domnich M, Bordbari S, Pylaeva E, Siakaeva E, Spyra I, Ozel I, Droege F, Squire A, Lienenklaus S, Sutter K, Hasenberg A, Gunzer M, Lang S, Jablonska J
https://pubmed.ncbi.nlm.nih.gov/35737452/
Gold Nanorods Induce Endoplasmic Reticulum Stress and Autocrine Inflammatory Activation in Human Neutrophils.
ACS Nano; 2022-06-23; 16(4): ; doi:10.1021/acschembio.0c00757
https://pubs.acs.org/doi/10.1021/acsnano.2c03586
Schirrmann R, Erkelenz M, Lamers K, Sritharan O, Nachev M, Sures B, Schlücker S, Brandau S
Bacteria (E. coli ) take up ultrasmall gold nanoparticles (2 nm) as shown by different optical microscopic techniques (CLSM, SIM, STORM).
Nano Select; 2022-06-14; (): ; doi:10.1002/nano.202200049
https://onlinelibrary.wiley.com/doi/full/10.1002/nano.202200049
Bia?as N, Sokolova V, van der Meer SB, Knuschke T, Ruks T, Klein K, Westendorf AM, Epple M
https://pubmed.ncbi.nlm.nih.gov/35697379/
Innate immune receptor signaling induces transient melanoma dedifferentiation while preserving immunogenicity.
Journal for ImmunoTherapy of Cancer; 2022-06-10; 6(): ; doi:10.1136/jitc-2021-003863
https://jitc.bmj.com/content/10/6/e003863.long
Thier B, Zhao F, Stupia S, Brüggemann A, Koch J, Schulze N, Horn S, Coch C, Hartmann G, Sucker A, Schadendorf D, Paschen A
https://pubmed.ncbi.nlm.nih.gov/35650266/
Persister state-directed transitioning and vulnerability in melanoma.
Nature Communications; 2022-06-01; 13(1): 3055; doi:https://doi.org/10.1038/s41467-022-30641-9
https://doi.org/10.1038/s41467-022-30641-9
Chauvistré H, Shannan B, Daignault-Mill SM, Ju RJ, Picard D, Egetemaier S, Váraljai R, Gibhardt CS, Sechi A, Kaschani F, Keminer O, Stehbens SJ, Liu Q, Yin X, Jeyakumar K, Vogel FCE, Krepler C, Rebecca VW, Kubat L, Lueong SS, Forster J, Horn S, Remke M, Ehrmann M, Paschen A, Becker JC, Helfrich I, Rauh D, Kaiser M, Gul S, Herlyn M, Bogeski I, Rodríguez-López JN, Haass NK, Schadendorf D, Roesch A.
https://pubmed.ncbi.nlm.nih.gov/35609021/
Long-term treatment with chloroquine increases lifespan in middle-aged male mice possibly via autophagy modulation, proteasome inhibition and glycogen metabolism.
Aging; 2022-05-23; 14(): ; doi:10.18632/aging.204069
https://www.aging-us.com/article/204069/text
Doeppner TR, Coman C, Burdusel D, Ancuta DL, Brockmeier U, Pirici DN, Yaoyun K, Hermann DM, Popa-Wagner A
https://pubmed.ncbi.nlm.nih.gov/35565295/
RB1-Negative Retinal Organoids Display Proliferation of Cone Photoreceptors and Loss of Retinal Differentiation
Cancers; 2022-04-26; 14(9): 2166; doi:10.3390/cancers14092166
Kanber D, Woesfeld J, Döpper H, Bozet M, Brenzel A, Altmüller J, Kilpert D, Pommerenke C, Steenpass L
https://pubmed.ncbi.nlm.nih.gov/34530440/
Sublamina-Specific Dynamics and Ultrastructural Heterogeneity of Layer 6 Excitatory Synaptic Boutons in the Adult Human Temporal Lobe Neocortex.
Cerebral Cortex; 2022-04-20; 32(9): 1840-1865; doi: https://doi.org/10.1093/cercor/bhab315
https://academic.oup.com/cercor/advance-article/doi/10.1093/cercor/bhab315/6371350
Schmuhl-Giesen S, Rollenhagen A, Walkenfort B, Yakoubi R, Sätzler K, Miller D, von Lehe M, Hasenberg M, Lübke JHR
Efficient Small Extracellular Vesicles (EV) Isolation Method and Evaluation of EV-Associated DNA Role in Cell–Cell Communication in Cancer
Cancers; 2022-04-20; 14(9): 2068; doi:https://doi.org/10.3390/cancers14092068
https://doi.org/10.3390/cancers14092068
Chetty VK, Ghanam J, Anchan S, Reinhardt K, Brenzel A, Gelléri M, Cremer C, Grueso-Navarro E, Schneider M, von Neuhoff N, Reinhardt D, Jablonska J, Nazarenko I, Thakur BK
https://pubmed.ncbi.nlm.nih.gov/34751438/
SIRT1-mediated deacetylation of FOXO3a transcription factor supports pro-angiogenic activity of interferon-deficient tumor-associated neutrophils
International Journal of cancer; 2022-04-01; 150(7): 1198-1211; doi:10.1002/ijc.33871
https://onlinelibrary.wiley.com/doi/10.1002/ijc.33871
Bordbari S, Mörchen B, Pylaeva E, Siakaeva E, Spyra I, Domnich M, Droege F, Kanaan O, Lang KS, Schadendorf D, Lang S, Helfrich I, Jablonska J
Free flow electrophoresis allows quick and reproducible preparation of extracellular vesicles from conditioned cell culture media
Extracellular Vesicles and Circulating Nucleic Acids; 2022-03-22; 3(): 31-48; doi:
https://evcna.com/article/view/4702
Staubach S, Tertel T, Walkenfort B, Buschmann D, Pfaffl MW, Weber G, Giebel B
https://pubmed.ncbi.nlm.nih.gov/35289361/
Inhibition of azole-resistant Aspergillus fumigatus biofilm at various formation stages by antifungal drugs, including olorofim
Journal of Antimicrobial Chemotherapy; 2022-03-15; (): ; doi:10.1093/jac/dkac062
https://academic.oup.com/jac/advance-article/doi/10.1093/jac/dkac062/6548677
Kirchhoff L, Dittmer S, Furnica DT, Buer J, Steinmann E, Rath PM, Steinmann J
https://pubmed.ncbi.nlm.nih.gov/34779257/
An Early Wave of Macrophage Infiltration Intertwined with Antigen-Specific Proinflammatory T Cells and Browning of Adipose Tissue Characterizes the Onset of Orbital Inflammation in a Mouse Model of Graves' Orbitopathy.
Thyroid; 2022-03-01; 32(3): 283-293; doi:10.1089/thy.2021.0464
https://www.liebertpub.com/doi/10.1089/thy.2021.0464?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed
Philipp S, Horstmann M, Hose M, Daser A, Görtz GA, Jesenek C, Flögel U, Hansen W, Bechrakis N, Banga JPS, Eckstein A, Berchner-Pfannschmidt U
https://pubmed.ncbi.nlm.nih.gov/35251021/
Reactivity of NK Cells Against Ovarian Cancer Cells Is Maintained in the Presence of Calcium Phosphate Nanoparticles
Frontiers in Immunology; 2022-02-18; 13(830938): ; doi:https://doi.org/10.3389/fimmu.2022.830938
https://www.frontiersin.org/articles/10.3389/fimmu.2022.830938/full
Hrvat A, Schmidt M, Obholzer M, Benders S, Kollenda S, Horn PA, Epple M, Brandau S, Mallmann-Gottschalk N
https://pubmed.ncbi.nlm.nih.gov/35159369/
Induction of Survival of Motor Neuron (SMN) Protein Deficiency in Spinal Astrocytes by Small Interfering RNA as an In Vitro Model of Spinal Muscular Atrophy
Cells; 2022-02-05; 11(3): 558; doi:10.3390/cells11030558
https://www.mdpi.com/2073-4409/11/3/558/htm
Leo M, Schmitt LI, Fleischer M, Steffen R, Osswald C, Kleinschnitz C, Hagenacker T
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834272/
Distinct Actions of the Thyroid Hormone Transporters Mct8 and Oatp1c1 in Murine Adult Hippocampal Neurogenesis
Cells; 2022-02-02; 11(3): 524; doi:https://doi.org/10.3390/cells11030524
https://www.mdpi.com/2073-4409/11/3/524/htm
Mayerl S, Alcaide Martin A, Bauer R, Schwaninger M, Heuer H, Ffrench-Constant C
https://pubmed.ncbi.nlm.nih.gov/34848338/
Post-ischemic protein restriction induces sustained neuroprotection, neurological recovery, brain remodeling, and gut microbiota rebalancing.
Brain, Behavior, and Immunity; 2022-02-01; 100(): 134-144; doi: 10.1016/j.bbi.2021.11.016
https://www.sciencedirect.com/science/article/pii/S0889159121006127
de Carvalho TS, Singh V, Yusuf AM, Wang J, Schultz Moreira AR, Sanchez-Mendoza EH, Sardardi M, Nascentes Melo LM, Doeppner TR, Kehrmann J, Scholtysik R, Hitpass L, Gunzer M, Hermann DM
https://pubmed.ncbi.nlm.nih.gov/34389849/
Targeting early stages of cardiotoxicity from anti-PD1 immune checkpoint inhibitor therapy.
European Heart Journal; 2022-01-31; (): ; doi: 10.1093/eurheartj/ehab430
https://academic.oup.com/eurheartj/advance-article-abstract/doi/10.1093/eurheartj/ehab430/6352226?redirectedFrom=fulltext
Michel L, Helfrich I, Hendgen-Cotta UB, Mincu RI, Korste S, Mrotzek SM, Spomer A, Odersky A, Rischpler C, Herrmann K, Umutlu L, Coman C, Ahrends R, Sickmann A, Löffek S, Livingstone E, Ugurel S, Zimmer L, Gunzer M, Schadendorf D, Totzeck M, Rassaf T
https://pubmed.ncbi.nlm.nih.gov/35100966/
Characterisation of cold-induced mitochondrial fission in porcine aortic endothelial cells.
Journal of Molecular Medicine; 2022-01-31; 28(1): ; doi:10.1186/s10020-021-00430-z
https://molmed.biomedcentral.com/articles/10.1186/s10020-021-00430-z
Quiring L, Walter B, Lohaus N, Schwan D, Rech A, Dlugos A, Rauen U
https://pubmed.ncbi.nlm.nih.gov/35154145/
The Splenic Marginal Zone in Children Is Characterized by a Subpopulation of CD27-Negative, Lowly IGHV-Mutated B Cells
Frontiers in Immunology; 2022-01-27; 13(): ; doi:10.3389/fimmu.2022.825619
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.825619/full
Kibler A, Budeus B, Küppers R, Seifert M
https://pubmed.ncbi.nlm.nih.gov/35038735/
Canonical Thyroid Hormone Receptor ? Action Stimulates Hepatocyte Proliferation in Male Mice
Endocrinology; 2022-01-17; 163(3): ; doi:10.1210/endocr/bqac003
https://academic.oup.com/endo/article/163/3/bqac003/6509895?login=true#330181598
Hönes GS, Kerp H, Hoppe C, Kowalczyk M, Zwanziger D, Baba HA, Führer D, Moeller LC
https://pubmed.ncbi.nlm.nih.gov/34339499/
Thyroid Hormone Transporter Deficiency in Mice Impacts Multiple Stages of GABAergic Interneuron Development.
Cerebral Cortex; 2022-01-10; 32(2): 329-341; doi:10.1093/cercor/bhab211
https://academic.oup.com/cercor/article/32/2/329/6333075?login=false
Mayerl S, Chen J, Salveridou E, Boelen A, Darras VM, Heuer H
https://pubmed.ncbi.nlm.nih.gov/35013174/
Progranulin mediates immune evasion of pancreatic ductal adenocarcinoma through regulation of MHCI expression.
Nature communications; 2022-01-10; 13(1): 156; doi:https://doi.org/10.1038/s41467-021-27088-9
https://www.nature.com/articles/s41467-021-27088-9
Cheung PF, Yang J, Fang R, Borgers A, Krengel K, Stoffel A, Althoff K, Yip CW, Siu EHL, Ng LWC, Lang KS, Cham LB, Engel DR, Soun C, Cima I, Scheffler B, Striefler JK, Sinn M, Bahra M, Pelzer U, Oettle H, Markus P, Smeets EMM, Aarntzen EHJG, Savvatakis K, Liffers ST, Lueong SS, Neander C, Bazarna A, Zhang X, Paschen A, Crawford HC, Chan AWH, Cheung ST, Siveke JT.
https://pubmed.ncbi.nlm.nih.gov/34985948/
The role of DNA nanostructures in the catalytic properties of an allosterically regulated protease.
Science Advances; 2022-01-07; 8(1): ; doi:10.1126/sciadv.abk0425
https://www.science.org/doi/10.1126/sciadv.abk0425?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
Kosinski R, Perez JM, Schöneweiß EC, Ruiz-Blanco YB, Ponzo I, Bravo-Rodriguez K, Erkelenz M, Schlücker S, Uhlenbrock G, Sanchez-Garcia E, Saccà B
https://pubmed.ncbi.nlm.nih.gov/34847707/
Postischemic Neuroprotection Associated With Anti-Inflammatory Effects by Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles in Aged Mice.
Stroke; 2022-01-01; 53(1): ; doi:10.1161/STROKEAHA.121.035821
https://www.ahajournals.org/doi/full/10.1161/STROKEAHA.121.035821?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org
Wang C, Börger V, Mohamud Yusuf A, Tertel T, Stambouli O, Murke F, Freund N, Kleinschnitz C, Herz J, Gunzer M, Popa-Wagner A, Doeppner TR, Giebel B, Hermann DM
Fine structure of Nucleophaga striatae (Rozellomycota) developing within the nucleus of the free-living amoeba Thecamoeba foliovenanda
Endocytobiosis and Cell Research; 2021-09-09; 31(1): 1-4; doi:
https://zs.thulb.uni-jena.de/receive/jportal_jparticle_01026785
Michel R, Jastrow H , Corsaro D, Walochnik J, Mosel F, Müller, KD
https://pubmed.ncbi.nlm.nih.gov/35969658/
Deciphering the Emulsification Process to Create an Albumin-Perfluorocarbon-(o/w) Nanoemulsion with High Shelf Life and Bioresistivity.
Langmuir; 2021-08-30; 38(34): ; doi:10.1021/acs.langmuir.1c03388
https://pubs.acs.org/doi/10.1021/acs.langmuir.1c03388
Jaegers J, Haferkamp S, Arnolds O, Moog D, Wrobeln A, Nocke F, Cantore M, Pütz S, Hartwig A, Franzkoch R, Psathaki OE, Jastrow H, Schauerte C, Stoll R, Kirsch M, Ferenz KB