Publications 2023
https://pubmed.ncbi.nlm.nih.gov/37958857/
Surgical Site-Released Tissue Is Potent to Generate Bone onto TCP and PCL-TCP Scaffolds In Vitro
Int J Mol Sci; 2024-11-01; 24(21): 15877; doi:10.3390/ijms242115877
https://www.mdpi.com/1422-0067/24/21/15877
Rehage E, Sowislok A, Busch A, Papaeleftheriou E, Jansen M, Jäger M
https://pubmed.ncbi.nlm.nih.gov/38129531/
Tg1.4HBV-s-rec mice, a crossbred hepatitis B virus-transgenic model, develop mild hepatitis
Scientific Reports; 2023-12-20; 13(1): ; doi:10.1038/s41598-023-50090-8
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10739827/pdf/41598_2023_Article_50090.pdf
Schefczyk S, Luo X, Liang Y, Hasenberg M, Walkenfort B, Trippler M, Schuhenn J, Sutter K, Lu M, Wedemeyer H, Schmidt HH, Broering R
https://pubmed.ncbi.nlm.nih.gov/38081825/
ComplexEye: a multi-lens array microscope for high-throughput embedded immune cell migration analysis
Nature Communications; 2023-12-11; 14(1): ; doi:
https://www.nature.com/articles/s41467-023-43765-3#Ack1
Cibir Z, Hassel J, Sonneck J, Kowitz L, Beer A, Kraus A, Hallekamp G, Rosenkranz M, Raffelberg P, Olfen S, Smilowski K, Burkard R, Helfrich I, Tuz AA, Singh V, Ghosh S, Sickmann A, Klebl AK, Eickhoff JE, Klebl B, Seidl K, Chen J, Grabmaier A, Viga R, Gunzer M
https://pubmed.ncbi.nlm.nih.gov/38019346/
HPV-associated head and neck cancer is characterized by distinct profiles of CD8+ T cells and myeloid-derived suppressor cells
Cancer Immunology, Immunotherapy; 2023-11-29; (): ; doi:10.1007/s00262-023-03571-8
https://link.springer.com/article/10.1007/s00262-023-03571-8
Benjamin A. Kansy, Tim P. Wehrs, Kirsten Bruderek, Yu Si, Sonja Ludwig, Freya Droege, Pia Hasskamp, Uta Henkel, Nina Dominas, Thomas K. Hoffmann, Peter A. Horn, Martin Schuler, Thomas C. Gauler, Monika Lindemann, Stephan Lang, Agnes Bankfalvi & Sven Brandau
https://pubmed.ncbi.nlm.nih.gov/37887331/
Proteome Analysis of Thyroid Hormone Transporter Mct8/Oatp1c1-Deficient Mice Reveals Novel Dysregulated Target Molecules Involved in Locomotor Function
Cells; 2023-10-12; 12(20): ; doi:10.3390/cells12202487
https://www.mdpi.com/2073-4409/12/20/2487
Siemes D, Vancamp P, Markova B, Spangenberg P, Shevchuk O, Siebels B, Schlüter H, Mayerl S, Heuer H, Engel D R
https://pubmed.ncbi.nlm.nih.gov/37797679/
Modulation of Immune Responses to Liposomal Vaccines by Intrastructural Help
European Journal of Pharmaceutics and Biopharmaceutics; 2023-10-03; 192(): ; doi:10.1016/j.ejpb.2023.10.003
https://www.sciencedirect.com/science/article/pii/S0939641123002631?via%3Dihub
Damm D, Suleiman E, Wagner J T, Klessing St, Pfister F, Elsayed H, Walkenfort B, Stobrawe J, Mayer J, Lehner E, Müller-Schmucker S M, Hasenberg M, Wyatt R T , Vorauer-Uhl K, Temchura V, Überla K
https://pubmed.ncbi.nlm.nih.gov/37715288/
Neural precursor cell delivery induces acute post-ischemic cerebroprotection, but fails to promote long-term stroke recovery in hyperlipidemic mice due to mechanisms that include pro-inflammatory responses associated with brain hemorrhages
J Neuroinflammation; 2023-09-15; 20(): ; doi:10.1186/s12974-023-02894-8
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504699/pdf/12974_2023_Article_2894.pdf
Yin D, Wang C, Qi Y, Wang Y-C, Hagemann N, Mohamud Yusuf A, Dzyubenko E, Kaltwasser B, Tertel T, Giebel B, Gunzer M, Popa-Wagner A, Doeppner T R & Hermann D M
https://pubmed.ncbi.nlm.nih.gov/37731517/
CD47 blockade enhances phagocytosis of cardiac cell debris by neutrophils
IJC Heart & Vasculature; 2023-09-09; 48(): ; doi:10.1016/j.ijcha.2023.101269
https://www.sciencedirect.com/science/article/pii/S2352906723001008#s0010
Haj-Yehia E, Korste S, Jochem R, Lusha A, Roth A, Diezel N, Niroomand J, Stock P, Westendorf A M, Buer J, Hendgen-Cotta U B, Rassaf T, Totzeck M
https://pubmed.ncbi.nlm.nih.gov/37684704/
Electrolyte imbalance causes suppression of NK and T cell effector function in malignant ascites
Journal of Experimental & Clinical Cancer Research; 2023-09-08; 42(1): ; doi:10.1186/s13046-023-02798-8
https://jeccr.biomedcentral.com/articles/10.1186/s13046-023-02798-8
Hrvat A, Schmidt M, Wagner B, Zwanziger D, Kimmig R, Volbracht L, Brandau S & Mallmann-Gottschalk N
https://pubmed.ncbi.nlm.nih.gov/37561177/
On predatory fungi feeding on free-living amoebae harbouring yeast-like endoparasites
Parasitology Research; 2023-08-10; 122(10): 2385-2392; doi:10.1007/s00436-023-07940-1
https://link.springer.com/article/10.1007/s00436-023-07940-1
Corsaro D, Müller K-D, Mosel F, Jastrow H, Walochnik J, Michel R
https://pubmed.ncbi.nlm.nih.gov/37307933/
Thyroid hormone transporter Mct8/Oatp1c1 deficiency compromises proper oligodendrocyte maturation in the mouse CNS
Neurobiology of Disease; 2023-08-01; 184(): ; doi:10.1016/j.nbd.2023.106195
https://www.sciencedirect.com/science/article/pii/S0969996123002103?via%3Dihub
Mayerl St, Heuer H
https://pubmed.ncbi.nlm.nih.gov/37525015/
Interleukin 17 signaling supports clinical benefit of dual CTLA-4 and PD-1 checkpoint inhibition in melanoma.
Nature Cancer; 2023-07-31; (): ; doi:10.1038/s43018-023-00610-2
https://www.nature.com/articles/s43018-023-00610-2#Sec9
Váraljai R, Zimmer L, Al-Matary Y, Kaptein P, Albrecht LJ, Shannan B, Brase JC, Gusenleitner D, Amaral T, Wyss N, Utikal J, Flatz L, Rambow F, Reinhardt HC, Dick J, Engel DR, Horn S, Ugurel S, Sondermann W, Livingstone E, Sucker A, Paschen A, Zhao F, Placke JM, Klose JM, Fendler WP, Thommen DS, Helfrich I, Schadendorf D, Roesch A
https://pubmed.ncbi.nlm.nih.gov/37468677/
Spatio-functional organization in virocells of small uncultivated archaea from the deep biosphere.
ISME J; 2023-07-19; (): ; doi:10.1038/s41396-023-01474-1
https://www.nature.com/articles/s41396-023-01474-1
Banas I, Esser SP, Turzynski V, Soares A, Novikova P, May P, Moraru C, Hasenberg M, Rahlff J, Wilmes P, Klingl A, Probst AJ
https://pubmed.ncbi.nlm.nih.gov/37260026/
Fc N-glycosylation of autoreactive A? antibodies as a blood-based biomarker for Alzheimer's disease
Alzheimers. Dement.; 2023-06-01; (): ; doi:10.1002/alz.13124
https://alz-journals.onlinelibrary.wiley.com/doi/epdf/10.1002/alz.13124
Kronimus Y, Albus A, Hasenberg M, Walkenfort B, Seifert M, Budeus B, Gronewold J, Hermann DM, Ross JA, Lochnit G, Galuska SP, Marcus K, Sitek B, Klotsche J, Mengel D, Neumann S, Dodel R
https://pubmed.ncbi.nlm.nih.gov/37055321/
Independent human mesenchymal stromal cell–derived extracellular vesicle preparations differentially attenuate symptoms in an advanced murine graft-versus-host disease model.
Cytotherapy; 2023-04-12; 25(8): 821-836; doi:10.1016/j.jcyt.2023.03.008
https://www.isct-cytotherapy.org/article/S1465-3249(23)00070-1/fulltext
Madel RJ, Börger V, Dittrich R, Bremer M, Tertel T, Phuong NNT, Baba HA, Kordelas L, Staubach S, Stein F, Haberkant P, Hackl M, Grillari R, Grillari J, Buer J, Horn PA, Westendorf AM, Brandau S, Kirschning CJ, Giebel B
https://pubmed.ncbi.nlm.nih.gov/37028818/
Glucocorticoid activation by HSD11B1 limits T cell-driven interferon signaling and response to PD-1 blockade in melanoma
Journal for Immunotherapie of Cancer; 2023-04-11; 11(4): ; doi:10.1136/jitc-2021-004150
https://jitc.bmj.com/content/11/4/e004150.long
Martins Nascentes Melo L, Herrera-Rios D, Hinze D, Löffek S, Oezel I, Turiello R, Klein J, Leonardelli S, Westedt IV, Al-Matary Y, Egea-Rodriguez S, Brenzel A, Bau M, Sucker A, Hadaschik E, Wirsdörfer F, Hanenberg H, Uhlenbrock N, Rauh D, Po?niak J, Rambow F, Marine JC, Effern M, Glodde N, Schadendorf D, Jablonska J, Hölzel M, Helfrich I
https://pubmed.ncbi.nlm.nih.gov/37017567/
In Vitro and In Vivo Effect of the Imidazole Luliconazole against Lomentospora prolificans and Scedosporium spp.
Microbiol. Spectr.; 2023-04-05; 11(3): ; doi:10.1128/spectrum.05130-22
https://journals.asm.org/doi/pdf/10.1128/spectrum.05130-22
Furnica DT, Dittmer S, Scharmann U, Meis JF, Steinmann J, Rath PM, Kirchhoff L
https://pubmed.ncbi.nlm.nih.gov/37047026/
Anthracycline Therapy Modifies Immune Checkpoint Signaling in the Heart.
International Journal of Molecular Sciences; 2023-03-23; 24(7): ; doi:10.3390/ijms24076052
https://www.mdpi.com/1422-0067/24/7/6052
Korste S, Settelmeier S, Michel L, Odersky A, Stock P, Reyes F, Haj-Yehia E, Anker MS, Grüneboom A, Hendgen-Cotta UB, Rassaf T, Totzeck M
https://pubmed.ncbi.nlm.nih.gov/36982966/
Blockade of ß-Adrenergic Receptors by Nebivolol Enables Tumor Control Potential for Uveal Melanoma in 3D Tumor Spheroids and 2D Cultures.
International Journal of Molecular Sciences; 2023-03-20; 24(6): ; doi:10.3390/ijms24065894
https://www.mdpi.com/1422-0067/24/6/5894
Farhoumand LS, Liu H, Tsimpaki T, Hendgen-Cotta UB, Rassaf T, Bechrakis NE, Fiorentzis M, Berchner-Pfannschmidt U
Rapid and fully automated blood vasculature analysis in 3D light-sheet image volumes of different organs
Cell Reports Methods; 2023-03-17; 3(3): ; doi:10.1101/2022.09.14.507895
https://www.cell.com/cell-reports-methods/pdf/S2667-2375(23)00051-6.pdf
Spangenberg P, Hagemann N, Squire A, Förster N, Krauß SD, Qi Y, Yusuf AM, Wang J, Grüneboom A, Kowitz L, Korste S, Totzeck M, Cibir Z, Tuz AA, Singh V, Siemes D, Struensee L, Engel DR, Ludewig P, Melo LMN, Helfrich I, Chen J, Gunzer M, Hermann DM, Mosig A
Surgical Site-Released Tissue Is Potent to Generate Bone onto TCP and PCL-TCP Scaffolds In Vitro
Int J Mol Sci; 2024-11-01; 24(21): 15877; doi:10.3390/ijms242115877
https://www.mdpi.com/1422-0067/24/21/15877
Rehage E, Sowislok A, Busch A, Papaeleftheriou E, Jansen M, Jäger M
https://pubmed.ncbi.nlm.nih.gov/38129531/
Tg1.4HBV-s-rec mice, a crossbred hepatitis B virus-transgenic model, develop mild hepatitis
Scientific Reports; 2023-12-20; 13(1): ; doi:10.1038/s41598-023-50090-8
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10739827/pdf/41598_2023_Article_50090.pdf
Schefczyk S, Luo X, Liang Y, Hasenberg M, Walkenfort B, Trippler M, Schuhenn J, Sutter K, Lu M, Wedemeyer H, Schmidt HH, Broering R
https://pubmed.ncbi.nlm.nih.gov/38081825/
ComplexEye: a multi-lens array microscope for high-throughput embedded immune cell migration analysis
Nature Communications; 2023-12-11; 14(1): ; doi:
https://www.nature.com/articles/s41467-023-43765-3#Ack1
Cibir Z, Hassel J, Sonneck J, Kowitz L, Beer A, Kraus A, Hallekamp G, Rosenkranz M, Raffelberg P, Olfen S, Smilowski K, Burkard R, Helfrich I, Tuz AA, Singh V, Ghosh S, Sickmann A, Klebl AK, Eickhoff JE, Klebl B, Seidl K, Chen J, Grabmaier A, Viga R, Gunzer M
https://pubmed.ncbi.nlm.nih.gov/38019346/
HPV-associated head and neck cancer is characterized by distinct profiles of CD8+ T cells and myeloid-derived suppressor cells
Cancer Immunology, Immunotherapy; 2023-11-29; (): ; doi:10.1007/s00262-023-03571-8
https://link.springer.com/article/10.1007/s00262-023-03571-8
Benjamin A. Kansy, Tim P. Wehrs, Kirsten Bruderek, Yu Si, Sonja Ludwig, Freya Droege, Pia Hasskamp, Uta Henkel, Nina Dominas, Thomas K. Hoffmann, Peter A. Horn, Martin Schuler, Thomas C. Gauler, Monika Lindemann, Stephan Lang, Agnes Bankfalvi & Sven Brandau
https://pubmed.ncbi.nlm.nih.gov/37887331/
Proteome Analysis of Thyroid Hormone Transporter Mct8/Oatp1c1-Deficient Mice Reveals Novel Dysregulated Target Molecules Involved in Locomotor Function
Cells; 2023-10-12; 12(20): ; doi:10.3390/cells12202487
https://www.mdpi.com/2073-4409/12/20/2487
Siemes D, Vancamp P, Markova B, Spangenberg P, Shevchuk O, Siebels B, Schlüter H, Mayerl S, Heuer H, Engel D R
https://pubmed.ncbi.nlm.nih.gov/37797679/
Modulation of Immune Responses to Liposomal Vaccines by Intrastructural Help
European Journal of Pharmaceutics and Biopharmaceutics; 2023-10-03; 192(): ; doi:10.1016/j.ejpb.2023.10.003
https://www.sciencedirect.com/science/article/pii/S0939641123002631?via%3Dihub
Damm D, Suleiman E, Wagner J T, Klessing St, Pfister F, Elsayed H, Walkenfort B, Stobrawe J, Mayer J, Lehner E, Müller-Schmucker S M, Hasenberg M, Wyatt R T , Vorauer-Uhl K, Temchura V, Überla K
https://pubmed.ncbi.nlm.nih.gov/37715288/
Neural precursor cell delivery induces acute post-ischemic cerebroprotection, but fails to promote long-term stroke recovery in hyperlipidemic mice due to mechanisms that include pro-inflammatory responses associated with brain hemorrhages
J Neuroinflammation; 2023-09-15; 20(): ; doi:10.1186/s12974-023-02894-8
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504699/pdf/12974_2023_Article_2894.pdf
Yin D, Wang C, Qi Y, Wang Y-C, Hagemann N, Mohamud Yusuf A, Dzyubenko E, Kaltwasser B, Tertel T, Giebel B, Gunzer M, Popa-Wagner A, Doeppner T R & Hermann D M
https://pubmed.ncbi.nlm.nih.gov/37731517/
CD47 blockade enhances phagocytosis of cardiac cell debris by neutrophils
IJC Heart & Vasculature; 2023-09-09; 48(): ; doi:10.1016/j.ijcha.2023.101269
https://www.sciencedirect.com/science/article/pii/S2352906723001008#s0010
Haj-Yehia E, Korste S, Jochem R, Lusha A, Roth A, Diezel N, Niroomand J, Stock P, Westendorf A M, Buer J, Hendgen-Cotta U B, Rassaf T, Totzeck M
https://pubmed.ncbi.nlm.nih.gov/37684704/
Electrolyte imbalance causes suppression of NK and T cell effector function in malignant ascites
Journal of Experimental & Clinical Cancer Research; 2023-09-08; 42(1): ; doi:10.1186/s13046-023-02798-8
https://jeccr.biomedcentral.com/articles/10.1186/s13046-023-02798-8
Hrvat A, Schmidt M, Wagner B, Zwanziger D, Kimmig R, Volbracht L, Brandau S & Mallmann-Gottschalk N
https://pubmed.ncbi.nlm.nih.gov/37561177/
On predatory fungi feeding on free-living amoebae harbouring yeast-like endoparasites
Parasitology Research; 2023-08-10; 122(10): 2385-2392; doi:10.1007/s00436-023-07940-1
https://link.springer.com/article/10.1007/s00436-023-07940-1
Corsaro D, Müller K-D, Mosel F, Jastrow H, Walochnik J, Michel R
https://pubmed.ncbi.nlm.nih.gov/37307933/
Thyroid hormone transporter Mct8/Oatp1c1 deficiency compromises proper oligodendrocyte maturation in the mouse CNS
Neurobiology of Disease; 2023-08-01; 184(): ; doi:10.1016/j.nbd.2023.106195
https://www.sciencedirect.com/science/article/pii/S0969996123002103?via%3Dihub
Mayerl St, Heuer H
https://pubmed.ncbi.nlm.nih.gov/37525015/
Interleukin 17 signaling supports clinical benefit of dual CTLA-4 and PD-1 checkpoint inhibition in melanoma.
Nature Cancer; 2023-07-31; (): ; doi:10.1038/s43018-023-00610-2
https://www.nature.com/articles/s43018-023-00610-2#Sec9
Váraljai R, Zimmer L, Al-Matary Y, Kaptein P, Albrecht LJ, Shannan B, Brase JC, Gusenleitner D, Amaral T, Wyss N, Utikal J, Flatz L, Rambow F, Reinhardt HC, Dick J, Engel DR, Horn S, Ugurel S, Sondermann W, Livingstone E, Sucker A, Paschen A, Zhao F, Placke JM, Klose JM, Fendler WP, Thommen DS, Helfrich I, Schadendorf D, Roesch A
https://pubmed.ncbi.nlm.nih.gov/37468677/
Spatio-functional organization in virocells of small uncultivated archaea from the deep biosphere.
ISME J; 2023-07-19; (): ; doi:10.1038/s41396-023-01474-1
https://www.nature.com/articles/s41396-023-01474-1
Banas I, Esser SP, Turzynski V, Soares A, Novikova P, May P, Moraru C, Hasenberg M, Rahlff J, Wilmes P, Klingl A, Probst AJ
https://pubmed.ncbi.nlm.nih.gov/37260026/
Fc N-glycosylation of autoreactive A? antibodies as a blood-based biomarker for Alzheimer's disease
Alzheimers. Dement.; 2023-06-01; (): ; doi:10.1002/alz.13124
https://alz-journals.onlinelibrary.wiley.com/doi/epdf/10.1002/alz.13124
Kronimus Y, Albus A, Hasenberg M, Walkenfort B, Seifert M, Budeus B, Gronewold J, Hermann DM, Ross JA, Lochnit G, Galuska SP, Marcus K, Sitek B, Klotsche J, Mengel D, Neumann S, Dodel R
https://pubmed.ncbi.nlm.nih.gov/37055321/
Independent human mesenchymal stromal cell–derived extracellular vesicle preparations differentially attenuate symptoms in an advanced murine graft-versus-host disease model.
Cytotherapy; 2023-04-12; 25(8): 821-836; doi:10.1016/j.jcyt.2023.03.008
https://www.isct-cytotherapy.org/article/S1465-3249(23)00070-1/fulltext
Madel RJ, Börger V, Dittrich R, Bremer M, Tertel T, Phuong NNT, Baba HA, Kordelas L, Staubach S, Stein F, Haberkant P, Hackl M, Grillari R, Grillari J, Buer J, Horn PA, Westendorf AM, Brandau S, Kirschning CJ, Giebel B
https://pubmed.ncbi.nlm.nih.gov/37028818/
Glucocorticoid activation by HSD11B1 limits T cell-driven interferon signaling and response to PD-1 blockade in melanoma
Journal for Immunotherapie of Cancer; 2023-04-11; 11(4): ; doi:10.1136/jitc-2021-004150
https://jitc.bmj.com/content/11/4/e004150.long
Martins Nascentes Melo L, Herrera-Rios D, Hinze D, Löffek S, Oezel I, Turiello R, Klein J, Leonardelli S, Westedt IV, Al-Matary Y, Egea-Rodriguez S, Brenzel A, Bau M, Sucker A, Hadaschik E, Wirsdörfer F, Hanenberg H, Uhlenbrock N, Rauh D, Po?niak J, Rambow F, Marine JC, Effern M, Glodde N, Schadendorf D, Jablonska J, Hölzel M, Helfrich I
https://pubmed.ncbi.nlm.nih.gov/37017567/
In Vitro and In Vivo Effect of the Imidazole Luliconazole against Lomentospora prolificans and Scedosporium spp.
Microbiol. Spectr.; 2023-04-05; 11(3): ; doi:10.1128/spectrum.05130-22
https://journals.asm.org/doi/pdf/10.1128/spectrum.05130-22
Furnica DT, Dittmer S, Scharmann U, Meis JF, Steinmann J, Rath PM, Kirchhoff L
https://pubmed.ncbi.nlm.nih.gov/37047026/
Anthracycline Therapy Modifies Immune Checkpoint Signaling in the Heart.
International Journal of Molecular Sciences; 2023-03-23; 24(7): ; doi:10.3390/ijms24076052
https://www.mdpi.com/1422-0067/24/7/6052
Korste S, Settelmeier S, Michel L, Odersky A, Stock P, Reyes F, Haj-Yehia E, Anker MS, Grüneboom A, Hendgen-Cotta UB, Rassaf T, Totzeck M
https://pubmed.ncbi.nlm.nih.gov/36982966/
Blockade of ß-Adrenergic Receptors by Nebivolol Enables Tumor Control Potential for Uveal Melanoma in 3D Tumor Spheroids and 2D Cultures.
International Journal of Molecular Sciences; 2023-03-20; 24(6): ; doi:10.3390/ijms24065894
https://www.mdpi.com/1422-0067/24/6/5894
Farhoumand LS, Liu H, Tsimpaki T, Hendgen-Cotta UB, Rassaf T, Bechrakis NE, Fiorentzis M, Berchner-Pfannschmidt U
Rapid and fully automated blood vasculature analysis in 3D light-sheet image volumes of different organs
Cell Reports Methods; 2023-03-17; 3(3): ; doi:10.1101/2022.09.14.507895
https://www.cell.com/cell-reports-methods/pdf/S2667-2375(23)00051-6.pdf
Spangenberg P, Hagemann N, Squire A, Förster N, Krauß SD, Qi Y, Yusuf AM, Wang J, Grüneboom A, Kowitz L, Korste S, Totzeck M, Cibir Z, Tuz AA, Singh V, Siemes D, Struensee L, Engel DR, Ludewig P, Melo LMN, Helfrich I, Chen J, Gunzer M, Hermann DM, Mosig A