ZMB Member Elke Cario
ZMB Member
Elke Cario
Next ZMB-Member
Prof. Dr. Elke Cario
Clinic for Gastroenterology and Hepatology
University Hospital Essen
Hufelandstr. 55
45147 Essen
- +49 201 723 4527
- Website
- Publications
- Publication Metrics
- ZMB Research Program
Molecular and Chemical Cell Biology
Research Overview
- Elucidation of innate immune checkpoints to maintain gut homeostasis
- Role and regulation of the intestinal epithelium in health and disease
- Regulatory mechanisms of xenobiotic-host metabolism mediated by gut microbiota and their consequences for cancer therapy
Publications
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Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathologyIn: PLoS Pathogens Vol. 16 (2020) Nr. 3, e1008340Online Full Text: dx.doi.org/ (Open Access)
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TRIM58 Restrains Intestinal Mucosal Inflammation by Negatively Regulating TLR2 in Myeloid CellsIn: The Journal of Immunology (JI) Vol. 203 (2019) Nr. 6, pp. 1636 - 1649Online Full Text: dx.doi.org/ (Open Access)
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MDR1A deficiency restrains tumor growth in murine colitis-associated carcinogenesisIn: PLoS ONE Vol. 12 (2017) Nr. 7, pp. e0180834Online Full Text: dx.doi.org/ (Open Access)
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P-glycoprotein multidrug transporter in inflammatory bowel diseases : More questions than answersIn: World Journal of Gastroenterology Vol. 23 (2017) Nr. 9, pp. 1513 - 1520Online Full Text: dx.doi.org/ (Open Access)
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Proteomics/phosphoproteomics of left ventricular biopsies from patients with surgical coronary revascularization and pigs with coronary occlusion/reperfusion : Remote ischemic preconditioningIn: Scientific Reports Vol. 7 (2017) Nr. 1,Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Assessing DNA methylation in the developing human intestinal epithelium : potential link to inflammatory bowel diseaseIn: Mucosal Immunology Vol. 9 (2016) Nr. 3, pp. 647 - 658Online Full Text: dx.doi.org/ (Open Access)
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Characterization of pancreatic glucagon-producing tumors and pituitary gland tumors in transgenic mice overexpressing MYCN in hGFAP-positive cellsIn: OncoTarget Vol. 7 (2016) Nr. 46, pp. 74415 - 74426Online Full Text: dx.doi.org/ (Open Access)
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MiR-205 and MiR-373 Are Associated with Aggressive Human Mucinous Colorectal CancerIn: PLoS ONE Vol. 11 (2016) Nr. 6, pp. e0156871Online Full Text: dx.doi.org/ (Open Access)
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Toll-like receptors in the pathogenesis of chemotherapy-induced gastrointestinal toxicityIn: Current Opinion in Supportive and Palliative Care Vol. 10 (2016) Nr. 2, pp. 157 - 164Online Full Text: dx.doi.org/
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TLR Signaling Modulates Side Effects of Anticancer Therapy in the Small IntestineIn: The Journal of Immunology (JI) Vol. 194 (2015) Nr. 4, pp. 1983 - 1995Online Full Text: dx.doi.org/ (Open Access)
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microRNA expression and its potential role in cardioprotection by ischemic postconditioning in pigsIn: Pflügers Archiv: European Journal of Physiology Vol. 466 (2014) Nr. 10, pp. 1953 - 1961Online Full Text: dx.doi.org/
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Loss of TLR2 worsens spontaneous colitis in MDR1A deficiency through commensally induced pyroptosisIn: The Journal of Immunology (JI) Vol. 190 (2013) Nr. 11, pp. 5676 - 5688Online Full Text: dx.doi.org/
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Microbiota and innate immunity in intestinal inflammation and neoplasiaIn: Current Opinion in Gastroenterology Vol. 29 (2013) Nr. 1, pp. 85 - 91Online Full Text: dx.doi.org/
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The human TLR4 variant D299G mediates inflammation-associated cancer progression in the intestinal epitheliumIn: OncoImmunology Vol. 2 (2013) Nr. 7, e24890Online Full Text: dx.doi.org/
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Commensal-Innate Immune Miscommunication in IBD PathogenesisIn: Digestive Diseases Vol. 30 (2012) Nr. 4, pp. 334 - 340Online Full Text: dx.doi.org/
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Nanotechnology-based drug delivery in mucosal immune diseases : hype or hope?In: Mucosal Immunology Vol. 5 (2012) Nr. 1, pp. 2 - 3
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IL-IR/MyD88 Signalling Mediates Severity of UC-Like Pancolitis in TLR2/MDRIA Double Deficient MiceIn: Gastroenterology Vol. 140 (2011) Nr. 5 Suppl. 1, pp. S143 - S144Online Full Text: dx.doi.org/
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Spontaneous bacterial keratitis in CD36 knockout miceIn: Investigative Ophthalmology & Visual Science, IOVS Vol. 52 (2011) Nr. 1, pp. 256 - 263Online Full Text: dx.doi.org/
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The Toll-like receptor (TLR) 4 variant D299G promotes inflammation-associated colon cancer progression in the intestinal epitheliumIn: Inflammatory Bowel Diseases Vol. 17 (2011) Nr. Suppl. 2, pp. S84Online Full Text: dx.doi.org/
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Toll-like Receptor 4 Variant D299G Induces Features of Neoplastic Progression in Caco-2 Intestinal Cells and Is Associated With Advanced Human Colon CancerIn: Gastroenterology Vol. 141 (2011) Nr. 6, pp. 2154 - 2165Online Full Text: dx.doi.org/
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Heads up! How the intestinal epithelium safeguards mucosal barrier immunity through the inflammasome and beyondIn: Current Opinion in Gastroenterology Vol. 26 (2010) Nr. 6, pp. 583 - 590Online Full Text: dx.doi.org/
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Toll-like receptors in inflammatory bowel diseases: A decade laterIn: Inflammatory Bowel Diseases Vol. 16 (2010) Nr. 9, pp. 1583 - 1597Online Full Text: dx.doi.org/ Online Full Text (Open Access)