ZMB Member Henning Reis
ZMB Member
Henning Reis
Next ZMB-Member
PD Dr. Henning Reis
Group
Uro-OncologyInstitute of Pathology
University Hospital Essen
Hufelandstraße 55
45147 Essen
- +49 201 723 3310
- Website
- Publications
- Publication Metrics
- ZMB Research Program
Oncology
Research Overview
Our research group is focused on translational and basic research in genito-urinary oncology. The group consists of physicians and basic scientists from the Institute of Pathology and Clinic of Urology. It therefore provides the optimal platform for cross-liking basic science and clinical-translational research. The working group has access to all modern analytical methods and is connected with national and international partner scientists and labs.
Our focus is not only on bladder and prostate cancer but also on renal and testicular cancer. In addition, we put emphasis on urachal cancer which is a rare cancer with particular expertise at our site. We aim to better understand its (molecular) backgrounds to foster (targeted) therapy in parallel to concepts in related tumor entities. We built up the largest cohort of urachal cancer cases yet in cooperation with national and international partners and established the urach cancer network (urachalcancer.org).
Publications
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Beyond driver mutations : Exploring the landscape of mutational signatures in adenocarcinomas of the bladderIn: The Journal of Pathology Vol. 263 (2024) Nr. 4-5, pp. 400 - 402Online Full Text: dx.doi.org/ (Open Access)
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Clinical sequencing identifies potential actionable alterations in a high rate of urachal and primary bladder adenocarcinomasIn: Cancer Medicine Vol. 12 (2023) Nr. 7, pp. 9041 CA Szarvas - 9054Online Full Text: dx.doi.org/ (Open Access)
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Detection of Clinically Significant Prostate Cancer Using Targeted Biopsy with Four Cores Versus Target Saturation Biopsy with Nine Cores in Transperineal Prostate Fusion Biopsy : A Prospective Randomized TrialIn: European Urology Oncology Vol. 6 (2023) Nr. 1, pp. 49 - 55Online Full Text: dx.doi.org/
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Discrepancy between German S3 Guideline Recommendations and Daily Urologic Practice in the Management of Nonmuscle Invasive Bladder Cancer : Results of a Binational SurveyIn: Urologia Internationalis Vol. 107 (2023) Nr. 1, pp. 35 - 45Online Full Text: dx.doi.org/
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Identification of a new prognostic score for patients with high-grade metastatic GEP-NEN treated with palliative chemotherapyIn: Journal of Cancer Research and Clinical Oncology Vol. 149 (2023) Nr. 8, pp. 4315 - 4325Online Full Text: dx.doi.org/ (Open Access)
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Immune-Checkpoint-Inhibitor Therapy : Principles and Relevance of Biomarkers for Pathologists and OncologistsIn: Advances in Anatomic Pathology Vol. 30 (2023) Nr. 3, pp. 160 - 166Online Full Text: dx.doi.org/
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Intraoperative Molecular Positron Emission Tomography Imaging for Intraoperative Assessment of Radical Prostatectomy SpecimensIn: European Urology Open Science Vol. 54 (2023) pp. 28 - 32Online Full Text: dx.doi.org/ (Open Access)
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Optimizing identification of consensus molecular subtypes in muscle-invasive bladder cancer : a comparison of two sequencing methods and gene sets using FFPE specimensIn: BMC Cancer Vol. 23 (2023) Nr. 1, 504Online Full Text: dx.doi.org/ (Open Access)
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Predictive value of molecular subtypes and APOBEC3G for adjuvant chemotherapy in urothelial bladder cancerIn: Cancer Medicine Vol. 12 (2023) Nr. 5, pp. 5222 - 5232Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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A quantitative polymerase chain reaction based method for molecular subtype classification of urinary bladder cancer : Stromal gene expressions show higher prognostic values than intrinsic tumor genesIn: International Journal of Cancer Vol. 150 (2022) Nr. 5, pp. 856 - 867Online Full Text: dx.doi.org/ (Open Access)
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Clinical outcome and quality of life in octogenarian patients with muscle-invasive urothelial carcinoma of the bladder treated with radical cystectomy or transurethral resection of the bladder tumor : a retrospective analysis of 143 patientsIn: International Urology and Nephrology Vol. 54 (2022) Nr. 1, pp. 71 - 79Online Full Text: dx.doi.org/ (Open Access)
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Commentary: Treatment Outcome of Different Chemotherapy in Patients With Relapsed or Metastatic Malignant Urachal TumorIn: Frontiers in Oncology Vol. 12 (2022) 864708Online Full Text: dx.doi.org/ (Open Access)
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Digital gene expression analysis of NSCLC-patients reveals strong immune pressure, resulting in an immune escape under immunotherapyIn: BMC Cancer Vol. 22 (2022) Nr. 1, 46Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Glycosaminoglycan Analysis of FFPE Tissues from Prostate Cancer and Benign Prostate Hyperplasia Patients Reveals Altered Regulatory Functions and Independent Markers for SurvivalIn: Cancers Vol. 14 (2022) Nr. 19, 4867Online Full Text: dx.doi.org/ (Open Access)
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Proteasomal Processing Immune Escape Mechanisms in Platinum-Treated Advanced Bladder CancerIn: Genes Vol. 13 (2022) Nr. 3, 422Online Full Text: dx.doi.org/ (Open Access)
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Rebiopsy in advanced non-small cell lung cancer, clinical relevance and prognostic implicationsIn: Lung Cancer Vol. 168 (2022) pp. 10 - 20Online Full Text: dx.doi.org/
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Retrograde Pyelography in the Presence of Urothelial Bladder Cancer Does Not Affect the Risk of Upper Tract Urothelial Cancer : A Retrospective Analysis of a Single-Centre CohortIn: Urologia Internationalis Vol. 106 (2022) pp. 638 - 643Online Full Text: dx.doi.org/ (Open Access)
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Strukturierte Befundung am Beispiel des Prostatakarzinoms : Selbstentwicklung einer digitalen Lösung für ProstatastanzbiopsienIn: Die Pathologie Vol. 43 (2022) Nr. Suppl. 1, pp. 94 - 100Online Full Text: dx.doi.org/
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The Prognostic Value of Cytokeratin and Extracellular Collagen Expression in Urinary Bladder CancerIn: Current Molecular Medicine Vol. 22 (2022) Nr. 10, pp. 941 - 949Online Full Text: dx.doi.org/
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Three-dimensional Magnetic Resonance Imaging-based Printed Models of Prostate Anatomy and Targeted Biopsy-proven Index Tumor to Facilitate Patient-tailored Radical Prostatectomy : A Feasibility StudyIn: European Urology Oncology Vol. 5 (2022) Nr. 3, pp. 357 - 361Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Treatment outcome of atypical EGFR mutations in the German National Network Genomic Medicine Lung Cancer (nNGM)In: Annals of Oncology Vol. 33 (2022) Nr. 6, pp. 602 - 615Online Full Text: dx.doi.org/ (Open Access)
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A new technological approach in diagnostic pathology : Mass spectrometry imaging-based metabolomics for biomarker detection in urachal cancerIn: Laboratory Investigation Vol. 101 (2021) Nr. 9, pp. 1281 - 1288Online Full Text: dx.doi.org/ (Open Access)
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Antitumor immune response is associated with favorable survival in GEP-NEN G3In: Endocrine-Related Cancer Vol. 28 (2021) Nr. 10, pp. 683 - 693Online Full Text: dx.doi.org/
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Apoptotic Gastritis in Melanoma Patients Treated With PD-1-Based Immune Checkpoint Inhibition : Clinical and Histopathological Findings Including the Diagnostic Value of Anti-Caspase-3 ImmunohistochemistryIn: Frontiers in Oncology Vol. 11 (2021) 725549Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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BRAF mutations and BRAF mutation functional class have no negative impact on the clinical outcome of advanced NSCLC and associate with susceptibility to immunotherapyIn: European Journal of Cancer (EJC) Vol. 149 (2021) pp. 211 - 221Online Full Text: dx.doi.org/
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Coronavirus disease 2019 vaccine mimics lymph node metastases in patients undergoing skin cancer follow-up : A monocentre studyIn: European Journal of Cancer (EJC) Vol. 154 (2021) pp. 167 - 174Online Full Text: dx.doi.org/ (Open Access)
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Correction to: : A new technological approach in diagnostic pathology: mass spectrometry imaging-based metabolomics for biomarker detection in urachal cancerIn: Laboratory Investigation Vol. 101 (2021) Nr. 10, pp. 1414Online Full Text: dx.doi.org/ (Open Access)
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Detection of Significant Prostate Cancer Using Target Saturation in Transperineal Magnetic Resonance Imaging/Transrectal Ultrasonography–fusion BiopsyIn: European Urology Focus Vol. 7 (2021) Nr. 6, pp. 1300 - 1307Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Enzalutamide enhances psma expression of psma-low prostate cancerIn: International Journal of Molecular Sciences (IJMS) Vol. 22 (2021) Nr. 14, 7431Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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High serum pd-l1 levels are associated with poor survival in urothelial cancer patients treated with chemotherapy and immune checkpoint inhibitor therapyIn: Cancers Vol. 13 (2021) Nr. 11, 2548Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Increased expression of akt3 in neuroendocrine differentiated prostate cancer cells alters the response towards anti‐androgen treatmentIn: Cancers Vol. 13 (2021) Nr. 3, pp. 578Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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MMP-7 Serum and Tissue Levels Are Associated with Poor Survival in Platinum-Treated Bladder Cancer PatientsIn: Diagnostics Vol. 11 (2021) Nr. 1, 48Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Molecular characterization of muellerian tumors of the urinary tractIn: Genes Vol. 12 (2021) Nr. 6, 880Online Full Text: dx.doi.org/ (Open Access)
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Multiple Hepatic and Pulmonary Tumors Combined with Bilateral Adrenal Masses in a Young Woman with von Hippel–Lindau DiseaseIn: Gastroenterology Vol. 161 (2021) Nr. 4, pp. e1 - e4Online Full Text: dx.doi.org/ (Open Access)
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Nodulärer Tumor eines Ductus deferens mit epithelialen VerbändenIn: Der Pathologe Vol. 42 (2021) Nr. 6, pp. 598 - 601Online Full Text: dx.doi.org/
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Prostate specific membrane antigen-radio guided surgery using Cerenkov luminescence imaging : Utilization of a short-pass filter to reduce technical pitfallsIn: Translational Andrology and Urology Vol. 10 (2021) Nr. 10, pp. 3972 - 3985Online Full Text: dx.doi.org/ (Open Access)
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Sitzungsbericht der Arbeitsgemeinschaft Uropathologie der Deutschen Gesellschaft für Pathologie 2021In: Der Pathologe Vol. 42 (2021) pp. 203 - 204Online Full Text: dx.doi.org/ (Open Access)
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The Biomarker Potential of Caveolin-1 in Penile CancerIn: Frontiers in Oncology Vol. 11 (2021) pp. 606122Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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The Genitourinary Pathology Society Update on Classification and Grading of Flat and Papillary Urothelial Neoplasia With New Reporting Recommendations and Approach to Lesions With Mixed and Early Patterns of NeoplasiaIn: Advances in Anatomic Pathology Vol. 28 (2021) Nr. 4, pp. 179 - 195Online Full Text: dx.doi.org/
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The Genitourinary Pathology Society Update on Classification of Variant Histologies, T1 Substaging, Molecular Taxonomy, and Immunotherapy and PD-L1 Testing Implications of Urothelial CancersIn: Advances in Anatomic Pathology Vol. 28 (2021) Nr. 4, pp. 196 - 208Online Full Text: dx.doi.org/
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The detection of isochromosome i(12p) in malignant germ cell tumours and tumours with somatic malignant transformation by the use of quantitative real-time polymerase chain reactionIn: Histopathology Vol. 78 (2021) Nr. 4, pp. 593 - 606Online Full Text: dx.doi.org/ (Open Access)
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Zystisches Nephrom bei einem 15 Monate alten Patienten mit DICER1-MutationIn: Der Urologe Vol. 60 (2021) Nr. 6, pp. 776 - 779Online Full Text: dx.doi.org/
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Angiomyolipom der Leber : Ein Fallbericht in Zusammenschau mit der LiteraturIn: Der Pathologe Vol. 41 (2020) Nr. 6, pp. 643 - 648Online Full Text: dx.doi.org/
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Biweekly Cetuximab Plus FOLFOX6 as First-Line Therapy in Patients With RAS Wild-Type Metastatic Colorectal Cancer : The CEBIFOX TrialIn: Clinical Colorectal Cancer Vol. 19 (2020) Nr. 4, pp. 236 - 247.e6Online Full Text: dx.doi.org/
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Caveolin-1 regulates the ASMase/ceramide-mediated radiation response of endothelial cells in the context of tumor–stroma interactionsIn: Cell Death and Disease Vol. 11 (2020) Nr. 4, 228Online Full Text: dx.doi.org/ (Open Access)
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Clinical response to crizotinib and emergence of resistance in lung adenocarcinoma harboring a MET c-Cbl binding site mutationIn: Lung Cancer Vol. 139 (2020) pp. 165 - 168Online Full Text: dx.doi.org/
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Comparative genomic profiling of glandular bladder tumoursIn: Virchows Archiv (2020)Online Full Text: dx.doi.org/ (Open Access)
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ERK phosphorylation as a marker of RAS activity and its prognostic value in non-small cell lung cancerIn: Lung Cancer Vol. 149 (2020) pp. 10 - 16Online Full Text: dx.doi.org/
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Editorial Comment from Dr Szarvas and Dr Reis to Clinicopathological features of malignant urachal tumor : A hospital-based cancer registry data in JapanIn: International Journal of Urology Vol. 27 (2020) Nr. 2, pp. 163 - 164Online Full Text: dx.doi.org/
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Ektopes Schilddrüsengewebe in der Nebenniere : Ein Fallbericht in Zusammenschau mit der LiteraturIn: Der Pathologe Vol. 41 (2020) Nr. 2, pp. 177 - 180Online Full Text: dx.doi.org/
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First-in-man intraoperative Cerenkov luminescence imaging for oligometastatic prostate cancer using ⁶⁸Ga-PSMA-11In: European Journal of Nuclear Medicine and Molecular Imaging Vol. 47 (2020) Nr. 13, pp. 3194 - 3195Online Full Text: dx.doi.org/
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GNAQ and GNA11 mutant nonuveal melanoma : A subtype distinct from both cutaneous and uveal melanomaIn: British Journal of Dermatology: BJD Vol. 183 (2020) Nr. 5, pp. 928 - 939Online Full Text: dx.doi.org/ (Open Access)
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Intraoperative 68Gallium-PSMA Cerenkov Luminescence Imaging for surgical margins in radical prostatectomy : A feasibility studyIn: Journal of Nuclear Medicine (JNM) Vol. 61 (2020) Nr. 10, pp. 1500 - 1506Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Machine learning reveals a PD-L1–independent prediction of response to immunotherapy of non-small cell lung cancer by gene expression contextIn: European Journal of Cancer (EJC) Vol. 140 (2020) pp. 76 - 85Online Full Text: dx.doi.org/
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Nuclear Localization of Robo is Associated with Better Survival in Bladder CancerIn: Pathology & Oncology Research Vol. 26 (2020) Nr. 1, pp. 253 - 261Online Full Text: dx.doi.org/
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Plasma next generation sequencing and droplet digital-qpcr-based quantification of circulating cell-free rna for noninvasive early detection of cancerIn: Cancers Vol. 12 (2020) Nr. 2, pp. 353Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Prevalence of APC and PTEN Alterations in Urachal CancerIn: Pathology & Oncology Research Vol. 26 (2020) Nr. 4, pp. 2773 - 2781Online Full Text: dx.doi.org/ (Open Access)
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STIP1 Tissue Expression Is Associated with Survival in Chemotherapy-Treated Bladder Cancer PatientsIn: Pathology & Oncology Research Vol. 26 (2020) Nr. 2, pp. 1243 - 1249Online Full Text: dx.doi.org/
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Serum and tissue syndecan-1 levels in renal cell carcinomaIn: Translational Andrology and Urology Vol. 9 (2020) Nr. 3, pp. 1167 - 1176Online Full Text: dx.doi.org/ (Open Access)
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Soluble syndecan-1 levels are associated with survival in platinum-treated bladder cancer patientsIn: Diagnostics Vol. 10 (2020) Nr. 11, 864Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Status der Verfügbarkeit und Anwendung von „next generation sequencing“ (NGS) beim Harnblasenkarzinom – eine Umfrage in der Arbeitsgemeinschaft UropathologieIn: Der Urologe Vol. 59 (2020) Nr. 3, pp. 318 - 325Online Full Text: dx.doi.org/
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Urachal cancer in Germany and the USA : An RKI/SEER population-based comparison studyIn: Urologia Internationalis Vol. 104 (2020) Nr. 9-10, pp. 803 - 809Online Full Text: dx.doi.org/
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Circulating and tissue IMP3 levels are correlated with poor survival in renal cell carcinomaIn: International Journal of Cancer Vol. 145 (2019) Nr. 2, pp. 531 - 539Online Full Text: dx.doi.org/ (Open Access)
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Classic bladder exstrophy and adenocarcinoma of the bladder : Methylome analysis provide no evidence for underlying disease-mechanisms of this associationIn: Cancer Genetics Vol. 235-236 (2019) pp. 18 - 20Online Full Text: dx.doi.org/
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Das Urachuskarzinom : Ein Update aktueller molekularer ErgebnisseIn: Der Pathologe Vol. 40 (2019) Nr. Suppl. 3, pp. 239 - 243Online Full Text: dx.doi.org/
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High soluble CGA levels are associated with poor survival in bladder cancerIn: Endocrine Connections Vol. 8 (2019) Nr. 5, pp. 625 - 633Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Impact of RAS mutation subtype on clinical outcome : A cross-entity comparison of patients with advanced non-small cell lung cancer and colorectal cancerIn: Oncogene Vol. 38 (2019) Nr. 16, pp. 2953 - 2966Online Full Text: dx.doi.org/
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Long-term Survival after resection for perihilar cholangiocarcinoma : Impact of UICC staging and surgical procedureIn: The Turkish Journal of Gastroenterology Vol. 30 (2019) Nr. 5, pp. 454 - 460Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Machine learning-based predictors for immune checkpoint inhibitor therapy of non-small-cell lung cancerIn: Annals of Oncology Vol. 30 (2019) Nr. 4, pp. 655 - 657Online Full Text: dx.doi.org/ (Open Access)
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Neoadjuvant cisplatin-based chemotherapy in “primary” and “secondary” muscle-invasive bladder cancer—is it a surrogate for molecular subtypes?In: Translational Cancer Research Vol. 8 (2019) Nr. Suppl. 2, pp. 176 - S179Online Full Text: dx.doi.org/ (Open Access)
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PD-L1 Expression in Urothelial Carcinoma with Predominant or Pure Variant Histology : Concordance among 3 Commonly Used and Commercially Available AntibodiesIn: The American Journal of Surgical Pathology Vol. 43 (2019) Nr. 7, pp. 920 - 927Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Programmed Death Ligand 1 (PD-L1) Status and Tumor-Infiltrating Lymphocytes in Hot Spots of Primary and Liver Metastases in Prostate Cancer With Neuroendocrine DifferentiationIn: Clinical Genitourinary Cancer Vol. 17 (2019) Nr. 2, pp. 145 - 153.e5Online Full Text: dx.doi.org/
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Progression-Related Loss of Stromal Caveolin 1 Levels Mediates Radiation Resistance in Prostate Carcinoma via the Apoptosis Inhibitor TRIAP1In: Journal of Clinical Medicine (JCM) Vol. 8 (2019) Nr. 3, 348Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Prospective comparison of ¹⁸F-FDG PET/MRI and ¹⁸F-FDG PET/CT for thoracic staging of non-small cell lung cancerIn: European Journal of Nuclear Medicine and Molecular Imaging Vol. 46 (2019) Nr. 2, pp. 437 - 445Online Full Text: dx.doi.org/
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Prädiktive Biomarker in der onkologischen UropathologieIn: Der Pathologe Vol. 40 (2019) Nr. 3, pp. 264 - 275Online Full Text: dx.doi.org/
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TRIM58 Restrains Intestinal Mucosal Inflammation by Negatively Regulating TLR2 in Myeloid CellsIn: The Journal of Immunology (JI) Vol. 203 (2019) Nr. 6, pp. 1636 - 1649Online Full Text: dx.doi.org/ (Open Access)
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Therapieprädiktive Biomarker des HarnblasenkarzinomsIn: Der Pathologe Vol. 40 (2019) Nr. Suppl. 3, pp. 331 - 338Online Full Text: dx.doi.org/
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Urachal cancer : current concepts of a rare cancerIn: Der Pathologe Vol. 40 (2019) Nr. Suppl. 1, pp. 31 - 39Online Full Text: dx.doi.org/
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Validation of survivin and HMGA2 as biomarkers for cisplatin resistance in bladder cancerIn: Urologic Oncology: Seminars and Original Investigations Vol. 37 (2019) Nr. 11, pp. 810.e7 - 810.e15Online Full Text: dx.doi.org/
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Biomarkers in Urachal Cancer and Adenocarcinomas in the Bladder : A Comprehensive Review Supplemented by Own DataIn: Disease Markers (2018) 7308168Online Full Text: dx.doi.org/ (Open Access)
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CA19-9 beim intrahepatischen Cholangiokarzinom : Ein diagnostisches und prognostisches Armamentarium?In: Der Chirurg Vol. 89 (2018) Nr. 6, pp. 466 - 471Online Full Text: dx.doi.org/
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Circulating syndecan-1 is associated with chemotherapy-resistance in castration-resistant prostate cancerIn: Urologic Oncology: Seminars and Original Investigations Vol. 36 (2018) Nr. 6, pp. 312.e9 - 312.e15Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Comparison of the sixth and the seventh editions of the UICC classification for intrahepatic cholangiocarcinomaIn: European Journal of Medical Research Vol. 23 (2018) Nr. 1, pp. 29Online Full Text: dx.doi.org/ (Open Access)
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Das Urachuskarzinom : aktuelle Konzepte einer seltenen TumorerkrankungIn: Der Pathologe Vol. 39 (2018) Nr. Supplement 2, pp. 291 - 300Online Full Text: dx.doi.org/
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MET Expression in Advanced Non–Small-Cell Lung Cancer : Effect on Clinical Outcomes of Chemotherapy, Targeted Therapy, and ImmunotherapyIn: Clinical Lung Cancer Vol. 19 (2018) Nr. 4, pp. e441 - e463Online Full Text: dx.doi.org/
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NF1 mutations in conjunctival melanomaIn: British Journal of Cancer (BJC) Vol. 118 (2018) Nr. 9, pp. 1243 - 1247Online Full Text: dx.doi.org/ (Open Access)
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Pathogenic and targetable genetic alterations in 70 urachal adenocarcinomasIn: International Journal of Cancer Vol. 143 (2018) Nr. 7, pp. 1764 - 1773Online Full Text: dx.doi.org/ (Open Access)
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Phosphorylation of p70 Ribosomal Protein S6 Kinase β-1 is an Independent Prognostic Parameter in Metastatic Colorectal CancerIn: Clinical Colorectal Cancer Vol. 17 (2018) Nr. 2, pp. e331 - e352Online Full Text: dx.doi.org/
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The Role of YKL-40 in Predicting Resistance to Docetaxel Chemotherapy in Prostate CancerIn: Urologia Internationalis Vol. 101 (2018) Nr. 1, pp. 65 - 73Online Full Text: dx.doi.org/
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Annexin A10 optimally differentiates between intrahepatic cholangiocarcinoma and hepatic metastases of pancreatic ductal adenocarcinoma : a comparative study of immunohistochemical markers and panelsIn: Virchows Archiv Vol. 470 (2017) Nr. 5, pp. 537 - 543Online Full Text: dx.doi.org/
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Cytomegalovirus reactivation in patients with refractory checkpoint inhibitor-induced colitisIn: European Journal of Cancer (EJC) Vol. 86 (2017) pp. 248 - 256Online Full Text: dx.doi.org/
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Eukaryotic elongation factor 2 is a prognostic marker and its kinase a potential therapeutic target in HCC.In: OncoTarget Vol. 8 (2017) Nr. 7, pp. 11950 - 11962Online Full Text: dx.doi.org/ (Open Access)
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Frequent GNAQ, GNA11, and EIF1AX Mutations in Iris MelanomaIn: Investigative Ophthalmology & Visual Science, IOVS Vol. 58 (2017) Nr. 9, pp. 3464 - 3470Online Full Text: dx.doi.org/ (Open Access)
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High Prevalence of Concomitant Oncogene Mutations in Prospectively Identified Patients with ROS1-Positive Metastatic Lung CancerIn: Journal of Thoracic Oncology Vol. 12 (2017) Nr. 1, pp. 54 - 64Online Full Text: dx.doi.org/ (Open Access)
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Impact of BCL2 polymorphisms on survival in transitional cell carcinoma of the bladderIn: Journal of Cancer Research and Clinical Oncology Vol. 143 (2017) Nr. 9, pp. 1659 - 1670Online Full Text: dx.doi.org/
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Liver steatosis in pre-transplant liver biopsies can be quantified rapidly and accurately by nuclear magnetic resonance analysisIn: Virchows Archiv Vol. 470 (2017) Nr. 2, pp. 197 - 204Online Full Text: dx.doi.org/
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MDR1A deficiency restrains tumor growth in murine colitis-associated carcinogenesisIn: PLoS ONE Vol. 12 (2017) Nr. 7, pp. e0180834Online Full Text: dx.doi.org/ (Open Access)
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Markers of Hippo-Pathway Activity in Tumor Forming Liver LesionsIn: Pathology & Oncology Research Vol. 23 (2017) Nr. 1, pp. 33 - 39Online Full Text: dx.doi.org/
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Molecular dissection of effector mechanisms of RAS-mediated resistance to anti-EGFR antibody therapyIn: OncoTarget Vol. 8 (2017) Nr. 28, pp. 45898 - 45917Online Full Text: dx.doi.org/ (Open Access)
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Progression-related loss of stromal Caveolin 1 levels fosters the growth of human PC3 xenografts and mediates radiation resistanceIn: Scientific Reports Vol. 7 (2017) pp. 41138Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Response to: Absence of GNAS and BRAF mutations but presence of KRAS mutation in urachal adenocarcinomaIn: Pathology Vol. 49 (2017) Nr. 5, pp. 561 - 562Online Full Text: dx.doi.org/
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SF3B1 and BAP1 mutations in blue nevus-like melanomaIn: Modern Pathology Vol. 30 (2017) Nr. 7, pp. 928 - 939Online Full Text: dx.doi.org/ Online Full Text (Open Access)
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Serum Chromogranin A as a Complementary Marker for the Prediction of Prostate Cancer-Specific SurvivalIn: Pathology & Oncology Research Vol. 23 (2017) Nr. 3, pp. 643 - 650Online Full Text: dx.doi.org/
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Telomerase reverse transcriptase (TERT) promoter mutations are rare in urachal cancerIn: Pathology International Vol. 67 (2017) Nr. 12, pp. 597 - 601Online Full Text: dx.doi.org/
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The role of beta-catenin mutation and SOX9 expression in sex cord-stromal tumours of the testisIn: Virchows Archiv Vol. 470 (2017) Nr. 4, pp. 421 - 428Online Full Text: dx.doi.org/
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Characterization of pancreatic glucagon-producing tumors and pituitary gland tumors in transgenic mice overexpressing MYCN in hGFAP-positive cellsIn: OncoTarget Vol. 7 (2016) Nr. 46, pp. 74415 - 74426Online Full Text: dx.doi.org/ (Open Access)
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Circulating U2 small nuclear RNA fragments as a diagnostic and prognostic biomarker in lung cancer patientsIn: Journal of Cancer Research and Clinical Oncology Vol. 142 (2016) Nr. 4, pp. 795 - 805Online Full Text: dx.doi.org/
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Circulating and Tissue Expression Levels of YKL-40 in Renal Cell CancerIn: The Journal of Urology Vol. 195 (2016) Nr. 4, pp. 1120 - 1125Online Full Text: dx.doi.org/
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Clinical Sequencing-guided Therapy of Urachal Carcinoma : New Perspective for a Rare CancerIn: European Urology Vol. 70 (2016) Nr. 5, pp. 776 - 777Online Full Text: dx.doi.org/
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Clinical, prognostic, and therapeutic aspects of urachal carcinoma—A comprehensive review with meta-analysis of 1,010 casesIn: Urologic Oncology: Seminars and Original Investigations Vol. 34 (2016) Nr. 9, pp. 388 - 398Online Full Text: dx.doi.org/
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End-ischemic reconditioning of liver allografts : Controlling the rewarmingIn: Liver Transplantation Vol. 22 (2016) Nr. 9, pp. 1223 - 1230Online Full Text: dx.doi.org/
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MiR-205 and MiR-373 Are Associated with Aggressive Human Mucinous Colorectal CancerIn: PLoS ONE Vol. 11 (2016) Nr. 6, pp. e0156871Online Full Text: dx.doi.org/ (Open Access)
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Mutations of KRAS, NRAS, BRAF, EGFR, and PIK3CA genes in urachal carcinoma : Occurence and prognostic significanceIn: OncoTarget Vol. 7 (2016) Nr. 26, pp. 39293 - 39301Online Full Text: dx.doi.org/ (Open Access)
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Novel immunohistochemical markers differentiate intrahepatic cholangiocarcinoma from benign bile duct lesionsIn: Journal of Clinical Pathology: JCP Online Vol. 69 (2016) Nr. 7, pp. 619 - 626Online Full Text: dx.doi.org/
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Oncogene status as a diagnostic tool in ocular and cutaneous melanomaIn: European Journal of Cancer (EJC) Vol. 57 (2016) pp. 112 - 117Online Full Text: dx.doi.org/
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Quantitative proteome analysis reveals the correlation between endocytosis-associated proteins and hepatocellular carcinoma dedifferentiationIn: Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics Vol. 1864 (2016) Nr. 11, pp. 1579 - 1585Online Full Text: dx.doi.org/
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Soluble syndecan-1 (SDC1) serum level as an independent pre-operative predictor of cancer-specific survival in prostate cancerIn: The Prostate Vol. 76 (2016) Nr. 11, pp. 977 - 985Online Full Text: dx.doi.org/
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Urachal Carcinoma of the Bladder: Impact of Clinical and Immunohistochemical Parameters on PrognosisIn: The Journal of Urology Vol. 195 (2016) Nr. 6, pp. 1690 - 1695Online Full Text: dx.doi.org/
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Validation of the diagnostic and prognostic relevance of serum MMP-7 levels in renal cell cancer by using a novel automated fluorescent immunoassay methodIn: International Urology and Nephrology Vol. 48 (2016) Nr. 3, pp. 355 - 361Online Full Text: dx.doi.org/
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(Cleaved) CK18 serum and tissue expression levels differentiate acute HCV reinfection from acute rejection in liver allograftsIn: Liver International Vol. 35 (2015) Nr. 3, pp. 905 - 913Online Full Text: dx.doi.org/
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A structured proteomic approach identifies 14-3-3Sigma as a novel and reliable protein biomarker in panel based differential diagnostics of liver tumorsIn: Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics Vol. 1854 (2015) Nr. 6, pp. 641 - 650Online Full Text: dx.doi.org/
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Analysis of SDHD promoter mutations in various types of melanomaIn: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Vol. 13 (2015) Nr. Suppl. 2, pp. 11Online Full Text: dx.doi.org/
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Analysis of SDHD promoter mutations in various types of melanomaIn: OncoTarget Vol. 6 (2015) Nr. 28, pp. 25868 - 25882Online Full Text: dx.doi.org/ (Open Access)
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Correlation of the apparent diffusion coefficient (ADC) with the standardized uptake value (SUV) in lymph node metastases of non-small cell lung cancer (NSCLC) patients using hybrid 18F-FDG PET/MRIIn: PLoS ONE Vol. 10 (2015) Nr. 1, e0116277Online Full Text: dx.doi.org/ (Open Access)
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Endothelial Caveolin-1 regulates the radiation response of epithelial prostate tumorsIn: Oncogenesis Vol. 4 (2015) pp. e148Online Full Text: dx.doi.org/ (Open Access)
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Frequent TERT Promoter Mutations in Ocular Surface Squamous NeoplasiaIn: Investigative Ophthalmology & Visual Science, IOVS Vol. 56 (2015) Nr. 10, pp. 5854 - 5861Online Full Text: dx.doi.org/ (Open Access)
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HER2 expression and markers of phosphoinositide-3-kinase pathway activation define a favorable subgroup of metastatic pulmonary adenocarcinomasIn: Lung Cancer Vol. 88 (2015) Nr. 1, pp. 34 - 41Online Full Text: dx.doi.org/
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Thoracic staging of non-small-cell lung cancer using integrated ¹⁸F-FDG PET/MR imaging : diagnostic value of different MR sequencesIn: European Journal of Nuclear Medicine and Molecular Imaging Vol. 42 (2015) Nr. 8, pp. 1257 - 1267Online Full Text: dx.doi.org/
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Enhanced stromal syndecan-1 expression is an independent risk factor for poor survival in bladder cancerIn: Human Pathology Vol. 45 (2014) Nr. 4, pp. 674 - 682Online Full Text: dx.doi.org/
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Identification of novel biomarker candidates for the immunohistochemical diagnosis of cholangiocellular carcinomaIn: Molecular and Cellular Proteomics (MCP) Vol. 13 (2014) Nr. 10, pp. 2661 - 2672Online Full Text: dx.doi.org/
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Infektiöse LungenerkrankungenIn: Der Pathologe Vol. 35 (2014) Nr. 6, pp. 606 - 611Online Full Text: dx.doi.org/
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Prognostic effect of serum and tissue YKL-40 levels in bladder cancerIn: Urologic Oncology: Seminars and Original Investigations Vol. 32 (2014) Nr. 5, pp. 663 - 669Online Full Text: dx.doi.org/
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Prognostic value of tissue and circulating levels of IMP3 in prostate cancerIn: International Journal of Cancer Vol. 135 (2014) Nr. 7, pp. 1596 - 1604Online Full Text: dx.doi.org/ (Open Access)
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Re: Association of Oncofetal Protein Expression with Clinical Outcomes in Patients with Urothelial Carcinoma of the BladderIn: The Journal of Urology Vol. 192 (2014) Nr. 2, pp. 617 - 618Online Full Text: dx.doi.org/
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Thoracic staging in lung cancer : prospective comparison of 18F-FDG PET/MR imaging and 18F-FDG PET/CTIn: Journal of Nuclear Medicine (JNM) Vol. 55 (2014) Nr. 3, pp. 373 - 378Online Full Text: dx.doi.org/ (Open Access)
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A new anastomotic leakage model in circular double stapled colorectal anastomosis after low anterior rectum resection in pigsIn: Journal of Investigative Surgery Vol. 26 (2013) Nr. 6, pp. 364 - 372Online Full Text: dx.doi.org/
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Comparison of the Sixth and the Seventh Editions of the UICC Classification for Perihilar CholangiocarcinomaIn: Annals of Surgical Oncology Vol. 20 (2013) Nr. 1, pp. 277 - 284Online Full Text: dx.doi.org/
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Feasibility of preemptive biomarker profiling for personalised early clinical drug development at a Comprehensive Cancer CenterIn: European Journal of Cancer (EJC) Vol. 49 (2013) Nr. 15, pp. 3076 - 3082Online Full Text: dx.doi.org/
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Inhibitory role of the small leucine-rich proteoglycan biglycan in bladder cancerIn: PLoS ONE Vol. 8 (2013) Nr. 11, pp. e80084Online Full Text: dx.doi.org/ (Open Access)
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Mammalian target of rapamycin pathway activity in alveolar soft part sarcomaIn: Human Pathology Vol. 44 (2013) Nr. 10, pp. 2266 - 2274Online Full Text: dx.doi.org/
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Oncogenic RAS simultaneously protects against anti-EGFR antibody-dependent cellular cytotoxicity and EGFR signaling blockadeIn: Oncogene Vol. 32 (2013) Nr. 23, pp. 2873 - 2881Online Full Text: dx.doi.org/
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Preemptive tumor profiling for biomarker-stratified early clinical drug development in metastatic breast cancer patientsIn: Breast Cancer Research and Treatment Vol. 142 (2013) Nr. 1, pp. 81 - 88Online Full Text: dx.doi.org/
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Talgdrüsenheterotopie im Ösophagus : Fallbericht in Zusammenschau mit der LiteraturIn: Der Pathologe Vol. 34 (2013) Nr. 2, pp. 162 - 164Online Full Text: dx.doi.org/
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High insulin-like growth factor mRNA-binding protein 3 (IMP3) protein expression is associated with poor survival in muscle-invasive bladder cancerIn: BJU International (BJUI) Vol. 110 (2012) Nr. 6B, pp. E308 - E317Online Full Text: dx.doi.org/ (Open Access)
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Serum endostatin levels correlate with enhanced extracellular matrix degradation and poor patients' prognosis in bladder cancerIn: International Journal of Cancer Vol. 130 (2012) Nr. 12, pp. 2922 - 2929Online Full Text: dx.doi.org/
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Targeting the anti-apoptotic protein BCL-XL to overcome RAS mediated resistance to anti-EGFR antibody therapy in colorectal cancerIn: Onkologie Vol. 35 (2012) Nr. Suppl. 6, pp. 253
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The Action of Small GTPases Rab11 and Rab25 in Vesicle Trafficking During Cell MigrationIn: Cellular Physiology and Biochemistry Vol. 29 (2012) Nr. 5-6, pp. 647 - 656Online Full Text: dx.doi.org/
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Tissue MMP-7 expression predicts survival in bladder cancer patients treated with cisplatin-based chemotherapyIn: Journal of Urology Vol. 187 (2012) Nr. Suppl. 4, pp. E575 - E575Online Full Text: dx.doi.org/
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Tumor vessel stabilization and remodeling by anti-angiogenic therapy with bevacizumabIn: Histochemistry and Cell Biology Vol. 137 (2012) Nr. 3, pp. 391 - 401Online Full Text: dx.doi.org/
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Elevated serum matrix metalloproteinase 7 levels predict poor prognosis after radical prostatectomyIn: International Journal of Cancer Vol. 128 (2011) Nr. 6, pp. 1486 - 1492Online Full Text: dx.doi.org/
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Expression of GLUT1 is associated with increasing grade of malignancy in non-invasive and invasive urothelial carcinomas of the bladderIn: Oncology Letters Vol. 2 (2011) Nr. 6, pp. 1149 - 1153Online Full Text: dx.doi.org/ (Open Access)
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Fulminant septic shock due to Clostridium perfringens skin and soft tissue infection eight years after liver transplantationIn: Annals of Transplantation Vol. 16 (2011) Nr. 3, pp. 143 - 146Online Full Text: dx.doi.org/
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Klatskin-mimicking lesions : Still a diagnostical and therapeutical dilemma?In: Hepatogastroenterology Journal Vol. 58 (2011) Nr. 106, pp. 265 - 269
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Lack of Association of the Genotype in the GNAS Fok I Polymorphism and Prostate CancerIn: Urologia Internationalis Vol. 87 (2011) Nr. 1, pp. 80 - 86Online Full Text: dx.doi.org/
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Rektale Magenschleimhautheterotopie : Ein Fallbericht in Zusammenschau mit der LiteraturIn: Der Pathologe Vol. 32 (2011) Nr. 6, pp. 521 - 524Online Full Text: dx.doi.org/
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TTF-1- (Klon 8G7G3/1) positives Kolonkarzinom : Diagnostische ImplikationenIn: Der Pathologe Vol. 32 (2011) Nr. 4, pp. 349 - 351Online Full Text: dx.doi.org/
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The Toll-like receptor (TLR) 4 variant D299G promotes inflammation-associated colon cancer progression in the intestinal epitheliumIn: Inflammatory Bowel Diseases Vol. 17 (2011) Nr. Suppl. 2, pp. S84Online Full Text: dx.doi.org/
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Toll-like Receptor 4 Variant D299G Induces Features of Neoplastic Progression in Caco-2 Intestinal Cells and Is Associated With Advanced Human Colon CancerIn: Gastroenterology Vol. 141 (2011) Nr. 6, pp. 2154 - 2165Online Full Text: dx.doi.org/
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Tumor markers as a diagnostic key for hilar cholangiocarcinomaIn: European Journal of Medical Research Vol. 15 (2010) Nr. 8, pp. 357 - 361Online Full Text: dx.doi.org/ (Open Access)
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Combined analysis of hypoxia-inducible factor 1 alpha and metallothionein indicates an aggressive subtype of colorectal carcinomaIn: International Journal of Colorectal Disease Vol. 24 (2009) Nr. 11, pp. 1287 - 1296Online Full Text: dx.doi.org/
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Activation of the ERK and AKT signalling pathway predicts poor prognosis in hepatocellular carcinoma and ERK activation in cancer tissue is associated with hepatitis C virus infectionIn: Journal of Hepatology Vol. 48 (2008) Nr. 1, pp. 83 - 90Online Full Text: dx.doi.org/
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AKT and ERK1/2 signaling in intrahepatic cholangiocarcinomaIn: World Journal of Gastroenterology Vol. 13 (2007) Nr. 48, pp. 6470Online Full Text: dx.doi.org/
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Elevated expression of cyclooxygenase-2 is a negative prognostic factor for overall survival in intrahepatic cholangiocarcinomaIn: Virchows Archiv Vol. 450 (2007) Nr. 2, pp. 135 - 141Online Full Text: dx.doi.org/ (Open Access)
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GNAS1 T393C polymorphism is associated with clinical course in patients with intrahepatic cholangiocarcinomaIn: Neoplasia: An International Journal for Oncology Research Vol. 9 (2007) Nr. 2, pp. 159 - 165Online Full Text: dx.doi.org/ (Open Access)